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Query: PF00483.23; GLGC_SYNY3/15-285; Nucleotidyl transferase, from PfamA32U

Results of FFAS03 search in VFDB
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst LAIILGGGAGTRLYPLTKLRAKPAVPLAGKYRLIDIPVSNCINSEIVKIYVLTQFNSASLNRHISRAYNFSGFQEGFVEVLAAQQTKDNPDWFQGTADAVRQYLWLFREWDVDEYLILSGDHLYRMDYAQFVKRHRETNADITLSVVPVDDRKAPELGLMKIDAQGRITDFSEKPQGEALRAMQVDTSVLGLSAEKAKLNPYIASMGIYVFKKEVLHNLLEKYEGATDFGKEIIPDSASDHNLQAYLFDDYWEDIGTIEAFYEANLALTKQLast
1 -89.200[M] KOG1322 GDP-mannose pyrophosphorylase/mannose-1-phosphate guanylyltransferase  ali follow..  61  86ASIILGGGAGTRLFPLTSKRAKPAVPIGGCYRLIDIPMSNCINSGIRKIFILTQFNSFSLNRHLSRTYNFGNGVNFEVLAATQTSGDAGKKWFQGTADAVRQFIWVFKTKNVEHVLILSGDHLYRMDYMNFVQKHIESNADITVSCLPMDESRASDFGLLKIDQSGKIIQFSEKPKGDDLKAMQVDTSILGLPPKEAAESPYIASMGVYVFRKEVLLKLLRSSPTSNDFGSEIIPLAVGEHNVQAFLFNDYWEDIGTIGSFFDANLALTEQ 365
2 -80.000[G] COG0448 ADP-glucose pyrophosphorylase  ali follow..  37  23LVLILAGGRGSRLYELTDKRAKPALYFGGNRRIIDFALSNCLNSGLNRIGVVTQYAAHSLLRHLQNGWSFLPARGEFIDMLPARQQIDDSTWYRGTADAVYQNMAIIRDHCPKYILILAGDHIYKQDYSQMLLDHIHSGAKCTVGCIEVEREKATEFGVMAVNENLKVKSFVEKPKDPPA--------------MVGKPNTSLASMGIYVFDADYLYDVLERPYTSHDFGKDILPKALEEGVLYAHPFEIYWRDVGTLDSFWQSNIDLVCE 296
3 -63.900[MJ] COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon)  ali follow..  26  3.AVLMAGGSGTRLRPLTCDLPKPMVPILNRP-IAEHIINLLKRHHITEVIATLHYLPDVLRDYFQDGGDFGVQMTYAVE----------EDQPLGTAGCVKNIAELLD----ETFLVISGDSITDFDLGEAIAFHKQKQSKATLILTRV--PNPIEFGVVITDEAGKIKRFLEKPSTSEIFS-------------------DTVNTGTYILEPEVLEYLPSN--TECDFSKDLFPLLLAKDPMYGYVAEGYWCDVGHLDAYREAQYDGLDR 235
4 -63.000[GMO] KOG1460 GDP-mannose pyrophosphorylase  ali follow..  19  11.AVIMVGGKGTRFRPLSLNIPKPLFPIAGQP-MVHHPISACKRIPLAQIYLVGFYEEREFALYVSASNELKVPVRYLR-----------EDKPHGSAGGLYHFRNLIMEDSPSHIFLLNCDVCCSFPLPKMLEAHRGYGGIGTLLVIKVSPESASQFGELVADVTNELLHYTEKPE---------------------TFVSDRINCGVYVFTPEIFNAIGDVSTDFVRLDQDILSPLAGKKRLYTYETMDFWEQIKSPGMSLRCSGLYLSQ 277
5 -59.900[M] COG1209 dTDP-glucose pyrophosphorylase  ali follow..  21  6.GIILAGGSGTRLYPVTMAVSKQLLPIYDKP-MIYYPLSTLMLAGIRDILIISTPDTPRFQQLLGDGSQWGLNLQYKV-----------QPSPDGLAQAFIIGEEFIGG--DDCALVLGDNIFYGHDLPKLMEAAVNKESGATVFAYHV--NDPERYGVVEFDKNGTAISLEEKPL---------------------EPKSNYAVTGLYFYDNDVVQMAKNLKPSARG--TDINRIYLEQGRSVAMMGRGYWLDTGTHQSLIEASNFIAT. 242
6 -53.400[M] COG1210 UDP-glucose pyrophosphorylase  ali follow..  20  8.AVIPAAGLGTRFLPATKAQPKEMLPIVDKP-AIQYIVEEAAESGIEDILIITGRNKRSIEDHFDRSAELEFNLREKGKT-LANIHYIRQKEPLGLGHAVLCAEHFIGD---EPFAVLLGDDIMVSELRQLMDVYDVYGTEV-VGVQSVLPEDVSKYGIINTSGSQEVNDLVEKPSPEEAPS-------------------EIAVMGRYVLNSSIFSVLKTIGRGAGN--TDALREVCRKEPIHARLLEGNRYDIGDKLGCFKASTEIGLM 272
7 -42.100[J] KOG1462 Translation initiation factor 2B, gamma subunit (eIF-2Bgamma/GCD1)  ali follow..  14  41.AVVFAGF-GNSLYPLTGSDPKALLPIGNKP-MLHYPLYWLEAAGFTSAILICMEEAEAHINAWLRSGYEGHMRIHVEAPTILDDS-------KSSADALRAVSHLIKSQKQNDFVCLSCDSIVGLPPIYGLDKFRLDNPSALAVYSPVQSKEIDAKQLIGIEEKTSRLLYAKSSADVGSDFTFRMSLLWKHPRV--TLNTNLSDAHIFVFKHWVI-DLIREKESISSIRGDLIPYLVKCQQKSFTVRENIQRFLSSPNNIDNYDGGLSSQ 315
8 -41.600[M] COG1213 Predicted sugar nucleotidyltransferases  ali follow..  17  3.AVILAAGFGSRLGHHTREIPKALLKIGKRP-LIYYTVQTLMENGIRDVVVVTGHKGYVLREYLSQFD------------LNFKFVHNSLYKKTNNIYSLYLAMDHVS----KGFYILNSDVLFHPGI--FRELHSSTKENLILSVDTF--KELGEEEMKVKIEDGVVKRISKQLNPSEADG---------------------EYIGIARVEENIIDDLYNERKGRRVFYEEAFQSMMDDGAVYYETTKGLWIEIDTPADLMKARYEIYPK 238
9 -40.500[M] COG4750 CTP:phosphocholine cytidylyltransferase involved in choline phosphorylation for cell surface LPS epitopes  ali follow..  12  3.AIILAAGLGTRLRPMTENTPKALVQVNQKP-LIEYQIEFLKEKGINDIIIIVGYLKEQFDYLKEK--------------YGVRLVFNDKYADYNNFYSLYLVKEELA----NSYVIDADNYLFKNMFRNDLTRS---------TYFSVYREDCTNEWFLVYGDDYKVQDIIVDSK------------------------AGRILSGVSFWDAPTAEKIVSFIDKAYVYWDNMVKDNIKELDVYVEELEGSIYEIDSVQDYRKLEEILKNE 228
10 -40.400[J] KOG1461 Translation initiation factor 2B, epsilon subunit (eIF-2Bepsilon/GCD6)  ali follow..  13  27.AILLADSFATKLLPLTLERPNVLLPLVNIP-MIDYTLAWLESAGIEEVFVFCSMQVIDYLNNSDWYSHKDFTVKTIES--------PQNSTSAGDALRYIYEQQIETSQIQGDFVLVNGCIVSNMPLTQLIQEHRDRKKKDEKAIMTMVIRNPLTKQLLYYDEDNICFSLLDRNPSVLLCSD-------------------MQDCYIDICSLEVLSLFVDNQHMRCDFVEGVLADDIIGYKIFTHEISCYASRIENFRSYDMVSKDIIQR 287
11 -22.500[M] COG1207 N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains)  ali follow..  17  8.IVILAAGKGTRMY---SKMPKVLHEIGGET-MLGRVIDTAAALNPQNICVVVGHGKEQVLDTVKRDVVW-----------------VEQTEQLGTGHAVKTALPHLAA--EGRTLVLYGDVIDVETLETLLEAAGNEVGLLTDVP-----ADPSGLGRIIRDSSGSVTAIVEEKD-----------------ADAAQKAVKEINTGILVLPNAKLEAWLNSLSSNNAQGEYYLTDLIDGIKIHPVQVRSSHLAAGVNNKLQLAELERIFQ 239
12 -22.400[M] COG0836 Mannose-1-phosphate guanylyltransferase  ali follow..  16  9TPVLLAGGAGSRLWPVSRDLPKQFQPLVGNLSTYQQTLKRVGDSLYSEPLVITNEDFRFF-------------ARRQAEEIDLPATVVLEPARRDSAAAMAAAAVLAERREPGCLVALAADHVVL-KFSEAVKLGAKAADQGNIVVFGLVPTEPTSYGYIKPGDA-TVDAFVEKPDVTTAIS----------------EKGYLWNSGNFLFRSDVMIAELKAPKNSIDYA-----VIEKTKRMAVVHGHFRWSDIGSWDAIWEI....... 286
13 -18.100[M] COG1212 CMP-2-keto-3-deoxyoctulosonic acid synthetase  ali follow..  14  5TVIIPARYASTRL-------GKPLAEIAGKP-MIAHVFEKAMQSGAKRVIVATD----------------HEQVATVARGFGAEVCMTSETHQSGT-ERLAEVVEKLGIAEDEIIVNIQGDEIPPAIVRQVAENLAKYQVKMASLAVNITDPEELF---VLTDHAGYVLYFSRAPIPWHRDQFASLPKEKSTRGQLVLSDHYLRHIGIYAYRAGFIKQYIQWQPSVLEQIESLLRVLWYGEKIHVELAREV-VGVDTAEDLEKVRSILEK. 258
14 -15.600[H] COG2266 GTP:adenosylcobinamide-phosphate guanylyltransferase  ali follow..  14  2LTLLMCGGKGTRLG----RGEKPLFEVCGMK-LIDHSLLQYKDF---DVIAITSPHTPATESYLAE-----------------KGVEVYRAAGKGYIEDYSEACRELAI--NEPVIVASADIIRDIAFDIVDAYMKTIKPALTVVM............................................................................................................................. 122
15 -12.800[R] COG2068 Uncharacterized MobA-related protein  ali follow..  16  13.IVLLAAGRSSRM-----GGPNKLLALFDGKPLVRRTAERALGSKASGTIVVTGHQRERVRAALSG---------------LDVTFADNPDFANGLSTSLKAGIAYLPE-DTAGAMIVLGDMVVSGDLDRLIDAFRKAGGNSVVR.............................................................................................................................. 137
16 -12.400[G] KOG2638 UDP-glucose pyrophosphorylase  ali follow..  11  110.VVKLNGGLGTSMG----KGPKSLIGVRNENTFLDLTVQQIENTDVPLVLMNSFNTDEDTKKILQKYNHCRVKIYTFNQSRYPRINKESAWYPPGHGDSFYNSLDTFIGEGKEYIFVSNIDNLGAT-LNHLINPPNGKRCEFVMEVTNKTRADVKGGTLTQYEGKLRLVEIAQVPKA-------------HVDEFKSVSKFKIFNTNNLWISLAAVKRLQEQNA............................................... 347
17 -10.600[G] COG4284 UDP-glucose pyrophosphorylase  ali follow..  12  106.VILMAGGQGTRLG---SSQPKGCYDIGSKKSLFQIQAEKLIKVEIPWYIMTSGPTRAATEAYFQEHNYFGLNKEQITFFNQGTLPAFDLTSPDGNGGAIKENNEDFDRRGIKHVYMYCVDNLSKIADPVFIGFAIKHGFELATKAVRKRDAHESVGLIATKNEKPCVIEYSEISN-----------ELAEAKDKDGLLKLRAGNIVNHYYLVDLLKRDLDQWCEN-------MPYHIAKKKI............................ 357
18 -10.400[I] COG1211 4-diphosphocytidyl-2-methyl-D-erithritol synthase  ali follow..  12  14.AVVPAAGIGSRMQ---MDKPKQYLHIHGKT-ILEHTLSVLLGYPIEKIILAVAANDPYISTCPLLTHP------------KIQLVEGGSSRADSVLNGLNAVKSAVQNSEDFWVMVHDAPCLTHQDLDKLVQVEDQNGAILAIPATDT---------IKRALHNQQIHYTEDRSQ............................................................................................... 166
19 -9.650[M] COG1083 CMP-N-acetylneuraminic acid synthetase  ali follow..  14  8IAIIPARAGSKGI--------KNLQLVGGVS-LVGRAILAAQESGFDQIVVTSD-----------GENILKEATKYGAKPVARPESLAQSD--TRTIDAILHCLETLNISQGTAALLQPTSPLRNADIRNAMEIFLGGKYKSVVSACECEHHPYKSFTL----EGTEVQPIHELTDF--------------ESPRQKLPKSYRANGAIYINDIQSLFE------EKRFFIAPMRFYLMPTYRSI---------DIDSTLDLQLAESLISKE 227
20 -9.060[H] COG0746 Molybdopterin-guanine dinucleotide biosynthesis protein A  ali follow..  18  5.NVLLAGGASRRF-----GEPKAFVKWKGRM-LYECAKEALGE----QTVIISRPEFIDRFQENGE---------------NEVYQDAEPFQGMGPLAGIYTA---FKKTDGDLYTVLSCDTLIQRRTMLELKRLMIAGADAVVPISDYHKRIMPVLYDQLSEKRLRISDLLGR................................................................................................. 159
FFAS is supported by the NIH grant R01-GM087218-01
1 4 7 6 9 1   jobs submitted since Jan 1, 2011
Comments and questions to: webmaster
Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Jaroszewski L, Rychlewski L, Godzik A. Improving the quality of twilight-zone alignments. Protein Sci. 2000 Aug;9(8):1487-96.