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Query: PF00834.19; RPE_SYNY3/6-205; Ribulose-phosphate 3 epimerase family, from PfamA32U

Results of FFAS03 search in VFDB
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst VVAPSILSADFSRLGEEIKAVDEAGADWIHVDVMDGRFVPNITIGPLIVDAIRPLTKKTLDVHLMIVEPEKYVEDFAKAGADIISVHVEHNASPHLHRTLCQIRELGKKAGAVLNPSTPLDFLEYVLPVCDLILIMSVNPGFGGQSFIPEVLPKIRALRQMCDERGLDPWIEVDGGLKPNNTWQVLEAGANAIVAGSAVFLast
1 -90.900[G] COG0036 Pentose-5-phosphate-3-epimerase  ali follow..  53  5LIAPSILSADFARLGEDTAKALAAGADVVHFDVMDNHYVPNLTIGPMVLKSLRNYITAPIDVHLMVKPVDRIVPDFAAAGASIITFHPEASE--HVDRTLQLIKENGCKAGLVFNPATPLSYLDYVMDKLDVILLMSVNPGFGGQSFIPQTLDKLREVRRRIDESGFDIRLEVDGGVKVNNIGEIAAAGADMFVAGSAIF 203
2 -87.300[G] KOG3111 D-ribulose-5-phosphate 3-epimerase  ali follow..  40  6FVCPSILNADLASLASECKKLLAAGADWLHLDVMDGHFVPNLTFGHPVVESLRKSAEPFFDVHLMVSNPGQWVEPMAKAGASQFTFHYEAVDGDAVSELIEKIRKSGMKVGLSVKPGTSVEHILKHANHLDNALIMTVEPGFGGQKFMENMMEKVRTIR----SKYPNLTIQVDGGVTPENIEISAQAGANAIVSGTGII 204
3 -31.200[G] COG0269 3-hexulose-6-phosphate synthase and related proteins  ali follow..  13  4..PMLQVALDNQTMDSAYETTRLIAE---EVDIIEVGTILCVGEGVRAVRDLKALPHKIVLADAKIADGKILSRMCFEANADWVTVICCADINT-AKGALDVAKEFNGDVQIELTGYWTWEQAQQWRDA-QVVYHRSRDAQAAGVAWGEADITAIKRLS------DMGFKVTVTGGLALEDLPLFKGIPIHVFIAGRSIR 195
4 -12.400[G] COG3010 Putative N-acetylmannosamine-6-phosphate epimerase  ali follow..  18  35.............VAAMAQASVIGGAAGLRIEGIENLKATRNVVNVPIIGIVKRDL---PDSPVRISPFLQDIEELAAAGADIIAFDGTDRVRPTREAIIKRIKELGCLAMADCSNFEEGMYCHNL---VEII-------GSTMSGYTGGEIPAEPDYQLVKDLNAAGCRVMAEGRYTPELAKTAIEIGAYSVTVGSAL. 210
5 -11.400[E] COG0159 Tryptophan synthase alpha chain  ali follow..  17  40.........SAEATFGIVKALVNGGADIIELGFADGPTIQALAAGMDIEHYFELVRGLGVEVPLVCMT-DKFVEHAADAGISGLII----IPVEEAADLKSSCEKYGLDLIFLVAPTTTDARIRKILERGSGFIYLVSRLGVTGAR------DVSGSTKELLSRVKTDIPKAVGFGISGKQAAEVRKAGADAVIVGSVF. 243
6 -11.300[E] KOG4175 Tryptophan synthase alpha chain  ali follow..  18  30.........TVKDTVPILKGFQDGGVDIIELGMADGPTIQLSN--PQTLEMVSQARNEGVTVPIILMG-ERFIQDAAKAGANGFII----LPPEEALKVRNYINDNGLSLIPLVAPSTTDERLELLSHIADSFVYVVSRMGTTGVQ--SSVASDLDELISRVRKYTKDTPLAVGFGVSTREHFQSVGSVADGVVIGSKI. 238
7 -10.600[R] COG1646 Predicted phosphate-binding enzymes, TIM-barrel fold  ali follow..  15  23LIDPEEQTPE--EAVEIARAAIRGGTDGIML----GGSTTDSSELDNTARALRENIDVPI-FMSLLNSTNPYWIIGAQALGAATVKKMGIEALPMGYLVVEPGGTVGWVGDTKPVPRNKPDIAAAYAMAAEFLGMRLFYLEAGSGAPEHVPEEMIALVKRCT-----DQILIVGGGISGEDAARVAGAGADVVVTGTVVE 229
8 -10.200[E] COG0135 Phosphoribosylanthranilate isomerase  ali follow..  12  15...............QDLQLAADSQADYLGFIFAESYRKVSPQDVKKWLSQVCVEKQV---AGVFVNESIETMSRIAELNLDVIQLHGD--EEPADADALRMLTDCEIWKALHHHENTTQE-IARFKDDVDGFVIDSSVKGGTGVAFSWDCVPEYQ-------QAAIGKRCFIAGGVNPDTITDLMKYQPAGIDLASGI. 189
9 -10.000[F] COG0516 IMP dehydrogenase/GMP reductase  ali follow..  23  26..................................................................NDTFVRVEKLIEAGVDAIVIDTAHGHSAGVINKISEIRQTFKDVVIVAGNVATAEGARALFEVGVDIVKVGIGPG---RVVAGVGVPQITAIYDCATAREFGKTIIADGGIYSGDIVKALAAGGNAVMLGSML. 162
10 -9.610[E] COG0106 Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase  ali follow..  17  34...............AQARAFEEQGFEWLHVVDLNGAF-AGETVNGAAVDAILKATKNPVQLGGGIRTLEH-IENWLSRGLKRVILGTVAVRDPALVIEACRKFPGRVAVGIDAKGGKVAVEGWAEASELGVVELARKFEGAGVAAIIYTDIDRWASTLELADA--VSIPVIASGGLASRRMTEPDAQKLEGAISGRALY 226
11 -9.170[R] COG0434 Predicted TIM-barrel enzyme  ali follow..  10  28...............DEVIDRAISDAAKYQEAGFDAIILENVSAFSVVANEVKREIALPLGINVLRNDCIAAYSIAYSIKADFIRVNV-AELRTRLPSRIDVLADVHVKHATHFSNFENALLDTIERGGADAVIVTGSRTG------SEVDIQELITAKRIS-----PVPVLVGSGVNPRNIKLFWRY-SDGFIVGTWV. 231
12 -9.130[S] COG3749 Uncharacterized protein conserved in bacteria  ali follow..  14  14.............................................SKIIKLQDGTPQIVADEWTVLRAPEG--SEVDAAARAIVPLAYWQANREALAS-----RARAGTLAVWLAPDDEPSALADDLASLPLVAV----PVFRGRGY--------STAFLLRQRLGFARELRAIGDVLRDQLDFMRRCGFDAFAVRAD.. 155
FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Jaroszewski L, Slabinski L, Wooley J, Deacon AM, Lesley SA, Wilson IA, Godzik A. Genome pool strategy for structural coverage of protein families. Structure. 2008 Nov 12;16(11):1659-67.