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Query: PF02424.15; C5BM31_TERTT/32-314; ApbE family, from PfamA32U

Results of FFAS03 search in VFDB
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MGTEVSITFWHDDPAQAQQLLADGMAEMRRLDRELSPWIESSELATLNRLAAKAPQKISSEMLFLVDKSLYFSHLTHGAFDITFASVGWFYDYREKKQPSEAQRSALLPAINYRWLKLDKTAGTLAYAHDNVRIDLGGIAKGYAVDRVAQLLENAGVRNATISAGGDSQIVGDKRGKPWIIGIKNPRDGGKEEAEAAILLPLENTAISTSGDYERYFIDQKTGERVHHIINPRTGKSVEGVVSVTILGPRGSDTDPMSTSVFVLGVEKGLALVNSLANFECIILast
1 -87.400[H] COG1477 Membrane-associated lipoprotein involved in thiamine biosynthesis  ali follow..  27  41MGTTYTVKYLSNNRDSPAEIQKRIDDALKEVNRQMSTYQPDSEISRFNQHTAGKPLRISSDFAHVTAEAVRLNRLTHGALDVTVGPLVNLWGFGPDREPSPEQIKQAASYTGIDKIILKQGKDYLSKTHPKAYLDLSSIAKGFGVDKVAGELEKYGIQNYLVEIGGELHGKGNARGEPWRIGIEQPNIVQG--GNTQIIVPLNNRSLATSGDYRIFHV-DKNGKRLSHIINPNNKRPISHLASISVVADSAMTADGLSTGLFVLGETEALKLAER-EKLAVFL 330
2 -35.300[S] COG2122 Uncharacterized conserved protein  ali follow..  11  10..................................................................ETIVTILTENEEFYKTAVKAILEARSEIEDYILHNPDFFTSYEPIECSGGEI---INRMCNAAKIAGVGPMAAVAGTIAAYAVEKMIDAGAKLAVVDNGGDIVIHS---DRELLVGIYPS-----------------KLAFKVPPVDYLAIC--TSSGKIGHSVSFGKAD------AATVVARDASVADALATALGNLIGDFGKKELEKTVSEFY.. 193
3 -5.790[R] COG1752 Predicted esterase of the alpha-beta hydrolase superfamily  ali follow..  18  36...............................................................................................................................VKPRIALALGG-ARGWAHIGVLKALDEEGIEVGMI-AGTSI---GALVGGCYLAGKLDELEAFARSLTVRRIAGLLDFAIGGGGRLTKRMQEHLQNLSIEDLDRPFVAVATEVYSGHEVWIEKGSLITAIRASYALPG.................. 175
4 -5.550[S] KOG0281 Beta-TrCP (transducin repeats containing)/Slimb proteins  ali follow..  9  227.....SIKIWDKTSLECLKVLTGHTGSVLCLQRVIVTGSSDSTVRVWDVNTGEVLNTLIHHNEAVLHLRFSNGLMVTCSKDRSI----AVWDMASA---TDITLRRVLVGHRAAVNVVDFDDKYIVSASGDRTIKVWSTSTC----EFVRTLNGHKRGIACLQYRDRLVVSGSSDNT-WDIECGACLRVLEGHEELVRCIRFDNKRIVSGAYDGKIKVWDLQAALDPR--APASTLCLRTLVE----HSGRVFRLQFDEFQIISSSHDDTILIWDFLNVPPS. 491
5 -5.530[E] COG0006 Xaa-Pro aminopeptidase  ali follow..  13  117...........................QSLVAEKLRCVKSTEEIQKMTRAAEIGSAGYDFVLAALLVRMLHVFWANLGIEKVSFPPIIAF-AAFPHAIPTNRSLKK----------------------GDVVLIDIGVCYEGYCSDMTRTVAFGATPEQQLLDGYVAVAEAQRAAIEFCRAGVP------------CRDVHKEAVRILRAHGMEKAFI---------HGLGHGVGREVHEYPRLSPFSDATLQLNMAVTV-TIMIGVNENLNLTNRKVSSEII 354
6 -5.430[F] COG0504 CTP synthase (UTP-ammonia lyase)  ali follow..  16  13.......................................................................................................................................VSSLGKGITAASLGRLLKNRGMKVTIQKFDPYINV---------DPGTMSPYQHGE-----VFVTDDGAETDLDLGHYERFIDINLNGKIYSSVLKKELGGTVQVIPHVTIKERVFRAGRETNADVVITEIGGTVGDIESLPFLEAI. 159
7 -5.350[F] KOG2387 CTP synthase (UTP-ammonia lyase)  ali follow..  21  11.......................................................................................................................................ISGIGKGVLASSTGMLLKTLGLKVTSIKIDPYMNI---------DAGTMSPLEHGE-----CFVLDDGGETDLDLGNYERYLGITTTGKIYSHVISRERGKTVQIVPHLT-VSKIPVDDTGLEPDVCIIELGGTVGDIESAPFVEAL. 163
8 -5.270[S] KOG0316 Conserved WD40 repeat-containing protein  ali follow..  10  37.GKDRTIRLWNPHRGILIKTYKSHGREVRDVNAKFCSCGGDRQVYYWDVSTGRVIRKFRGHDGEV--NAVKFNDSSSVVVSAGFDRSLRVWDCRSHSVEPVQIIDTFLDTV----MSVVLTKTEIIGGSVDGTVRTFDMRIG----REMSDNLGQPVNCISISNDGNCVLAGCLDST---LRLLDRTTGELLQVYKGHISKSFKTDCCLTNSDAHVIGGSEDGL---FFWDLVDAKVLSKFRAHDLVNSIDVDFYLRLLKFFVAGDKRELPPEGRLYV..... 303
9 -5.260[H] KOG1324 Dihydrofolate reductase  ali follow..  12  2............................................................................................................................................................LRFNLIVAVCENFGIGIRGDLPWRI----KSELKYFSRTTKRTSDPTKQNAVVMG------------KTYFGV--PESKRPLPDRLNI-VLSTTLQESDLPKGVLLCPNLETAMKILEEQNEVENIW 110
10 -5.190[S] COG5373 Predicted membrane protein  ali follow..  10  16...................AFLGGRRSAERLDREIES---KAEIARLAKEGMGEPGPDLATGRPSEAGVPSVAGTEATADGPWSRAREGAGTSHDESAAGRESGDGAIDGPVAPSAAAARAESLESRIGGRWPVWVGGLALALGG-----FLVQYSIEAGLLSFGLALGVAGE---------IRRRDVPAIADRFRNAMIP----GVLTAAGAVTLFGVVYAAYGIYDFIGTGAAFVLLALVSLATVGLSLLHGQALAGLGLLASLLTPLFVSSGEPRPWVLF 271
FFAS is supported by the NIH grant R01-GM087218-01
1 4 8 1 0 5   jobs submitted since Jan 1, 2011
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Li W, Godzik A. cd-hit: a fast program for clustering and comparing large sets of protein or nucleotide sequences. Bioinformatics. 2006 May 26;