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Query: PF14117.6; D0J295_COMT2/9-67; Domain of unknown function (DUF4287 topsan), from PfamA32U

Results of FFAS03 search in VFDB
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
    .   10    .   20    .   30    .   40    .   50    .
# Score Template Links and tools%idFirst GPASYFPSIEKAYGKPVTHWLKILDELRDKKHMEQVAHLKLEHGIGHGHANALVAYHRALast
1 -5.860[J] KOG1071 Mitochondrial translation elongation factor EF-Tsmt, catalyzes nucleotide exchange on EF-Tumt  ali follow..  17  27..KEALMALRKKTGYSYVNCRKALIQFGENDMDSAVKWLKEA................. 66
2 -5.510[J] COG2167 Ribosomal protein L39E  ali follow..  12  16.........AMKQNRRVPVWVIVKTNRRVLTHPKRRHWRRTK................. 48
3 -5.170[S] KOG4481 Uncharacterized conserved protein  ali follow..  19  111.............GKTVVEALTLLNNHKLSPETWTAEKIAQEYHLELEDVNSLLKYFVT 157
4 -4.690[R] KOG2802 Membrane protein HUEL (cation efflux superfamily)  ali follow..  15  262GSASMFSEAIHSLSDTCNQGLLALGISKSVQTPD------PSHPYGFSNMRYISSLISG 314
5 -4.460[OU] COG0740 Protease subunit of ATP-dependent Clp proteases  ali follow..  11  148..HTLNDRLAFHTGQGIERIEKDTDRD---------NFMSAEEAQAYGLVDEVLV.... 191
6 -4.370[J] KOG0002 60s ribosomal protein L39  ali follow..  11  163.........KQKQNRPIPQWIWM-KTGNKIRYNSKRTLEKNQAG............... 196
7 -4.280[P] COG1930 ABC-type cobalt transport system, periplasmic component  ali follow..  17  29GSDGEAESQIQAIAPQYKPWFQPLYEPASGEIESLLFTLQGSLGAA............. 74
8 -4.130[S] COG2862 Predicted membrane protein  ali follow..  20  77GYENFVSQLDISENKEKLNWLGKMDATSLK............................. 106
9 -3.930[S] KOG2706 Predicted membrane protein  ali follow..  22  319.RCWTFREGMKHWNVCVQYWLAVYKLFPSKKYRTGATLLCSAHGFRPGHYFCIMG.... 376
10 -3.810[S] COG4377 Predicted membrane protein  ali follow..  15  81.YGCLMAGIFEECGRYLM--MRFFMKRHHTWADGLA------FGAGHGGLEAIL..... 125
FFAS is supported by the NIH grant R01-GM087218-01
1 4 8 0 6 7   jobs submitted since Jan 1, 2011
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Pawlowski K, Pio F, Chu Z, Reed JC, Godzik A. PAAD - a new protein domain associated with apoptosis, cancer and autoimmune diseases. Trends Biochem Sci. 2001 Feb;26(2):85-7.