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Query: gi|15923009|ref|NP_370543.1| two-component sensor histidine kinase (SAV0019) [Staphylococcus aureus subsp. aureus Mu50], from S.aureus

Results of FFAS03 search in H.sapiens
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MKWLKQLQSLHTKLVIVYVLLIIIGMQIIGLYFTNNLEKELLDNFKKNITQYAKQLEISIEKVYDEKGSVNAQKDIQNLLSEYANRQEIGEIRFIDKDQIIIATTKQSNRSLINQKANDSSVQKALSLGQSNDHLILKDYGGGKDRVWVYNIPVKVDKKVIGNIYIESKINDVYNQLNNINQIFIVGTAISLLITVILGFFIARTITKPITDMRNQTVEMSRGNYTQRVKIYGNDEIGELALAFNNLSKRVQEAQANTESEKRRLDSVITHMSDGIIATDRRGRIRIVNDMALKMLGMAKEDIIGYYMLSVLSLEDEFKLEEIQENNDSFLLDLNEEEGLIARVNFSTIVQETGFVTGYIAVLHDVTEQQQVERERREFVANVSHELRTPLTSMNSYIEALEEGAWKDEELAPQFLSVTREETERMIRLVNDLLQLSKMDNESDQINKEIIDFNMFINKIINRHEMSAKDTTFIRDIPKKTIFTEFDPDKMTQVFDNVITNAMKYSRGDKRVEFHVKQNPLYNRMTIRIKDNGIGIPINKVDKIFDRFYRVDKARTRKMGGTGLGLAISKEIVEAHNGRIWANSVEGQGTSIFITLPCEVIEDGDWDELast
1 -32.900sp|O14874|BCKD_HUMAN [3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial OS=Homo sapiens GN=BCKDK PE=1 SV=2  ali follow..  18  133..........................................................................................................................................................................................................................................................................................................................................................................FQKLTDFPPIKDQADQLVRQLLDDHKDVVTLLEGLRESRKH--IEDEKLVRYFLDKTLTSRLGIRMLATHHLALHEDKPDFVGIICTRLSPKKIIEKWVDFARRLCEHKRVRIN-GHVAARFPFIPMPLDYILPELLKNAMRATMESHLDTVVITIANNDVDLIIRISDRGGGIAHKDLDRVMDYHFTTAEASTQDMHGFGFGLPTSRAYAEYLGGSLQLQSLQGIGTDVYLRLRHIDGREES... 409
2 -32.900sp|Q16654|PDK4_HUMAN [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 4, mitochondrial OS=Homo sapiens GN=PDK4 PE=1 SV=1  ali follow..  19  108...........................................................................................................................................................................................................................................................................................................................................................................DDQKALSDFVDTLIKVRNRHHNVVPTMAQGIIEYKDACTVDPVTNQNL-QYFLDRFYMNRISTRMLMNQHILIFSDSQTGNPSHIGSIDPNCDVVAVVQDAFECSRMTQVNGKFPDQPIHIVYVPSHLHHMLFELFKNAMRATVEHQENQIEVIVVLGKEDLTIKISDRGGGVPLRIIDRLFSYTYVMDNSRNAPLAGFGYGLPISRLYAKYFQGDLNLYSLSGYGTDAIIYLKALSSESIE... 373
3 -32.000sp|Q15119|PDK2_HUMAN(removed signalp:1-16) [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 2, mitochondrial OS=Homo sapiens GN=PDK2 PE=1 SV=2  ali follow..  15  88...........................................................................................................................................................................................................................................................................................................................................................................EDHRTLSQFTDALVTIRNRHNDVVPTMAQGVLEYKDTYGDDPVSNQNI-QYFLDRFYLSRISIRMLINQHTLIFDGSTNPAHPKHPNCNVSEVVKDAYDMAKLLCDKQEINAANSKQPIHMVYVPSHLYHMLFELFKNAMRATVESHESSIKVMVALGEEDLSIKMSDRGGGVPLRKIERLFSYMYSTAPTPQPGTGGFGYGLPISRLYAKYFQGDLQLFSMEGFGTDAVIYLKALSTDSVE... 353
4 -31.100sp|Q15120|PDK3_HUMAN [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 3, mitochondrial OS=Homo sapiens GN=PDK3 PE=1 SV=1  ali follow..  18  100...........................................................................................................................................................................................................................................................................................................................................................................EDPQVLDNFLQVLIKVRNRHNDVVPTMAQGVIEYKEKFGFDPFISTNI-QYFLDRFYTNRISFRMLINQHTLLFGGDTNPVHPKHPTCNVADVVKDAYETAKMLCEQEEFNAKAPDKPIQVVYVPSHLFHMLFELFKNSMRATVELYEDRVKTLVTLGKEDLSIKISDLGGGVPLRKIDRLFNYMYSLEPTRAAPLAGFGYGLPISRLYARYFQGDLKLYSMEGVGTDAVIYLKALSSESFE... 367
5 -30.700sp|Q15118|PDK1_HUMAN [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 1, mitochondrial OS=Homo sapiens GN=PDK1 PE=1 SV=1  ali follow..  18  118..........................................................................................................................................................................................................................................................................................................................................................................LQELLDFKDKSAEDAKAIYDFTDTVIRIRNRHNDVIPTMAQGVIETSQNVQYFLDRFYMSRISIRMLLNQHSLLFGGKGKGSPSHRKHIDGYENARRLCDLYYINSPELELEELNPGQPIQVVYVPSHLYHMVFELFKNAMRATMEHHANRIQVHVTLGNEDLTVKMSDRGGGVPLRKIDRLFNYMYRVETSRAVPLAGFGYGLPISRLYAQYFQGDLKLYSLEGYGTDAVIYIKALSTDSIE... 398
6 -18.400sp|O60658|PDE8A_HUMAN High affinity cAMP-specific and IBMX-insensitive 3`,5`-cyclic phosphodiesterase 8A OS=Homo sapiens GN=PDE8A PE=1 SV=2  ali   12  35..........................................................................................................................................................................................................................................VENPNIMACYNELLQLEFGEVRSQLKLRNSVFTALENSEDAIEITSEDRFIQYANPAFETTMGYQSGELIGKELGEVPINEKKADLLDTINSC-QGIYYAKKKNGDNINVKIIPVIGQGGKIRHYVSIIRVCNGNNKAEKIHSSMARIHSMTIEAPITKVINIINAAQESS--------------PMPVTEALDRVLEILRTTELYSPQFGAKDDDPHANDLVGGLMS.................................................................................................................................................. 300
7 -14.700sp|Q15751|HERC1_HUMAN Probable E3 ubiquitin-protein ligase HERC1 OS=Homo sapiens GN=HERC1 PE=1 SV=2  ali   11  6................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................TLGEQAAALANPHDRVVA----------LRRVTAAAQVLLARTMVMRALSLLSVSGSSCSLAAGLESLGLTDIRTLVRL-AGRAGLSTSPSAMASTSERSRGGHSKANK... 108
8 -14.600sp|O95263|PDE8B_HUMAN High affinity cAMP-specific and IBMX-insensitive 3`,5`-cyclic phosphodiesterase 8B OS=Homo sapiens GN=PDE8B PE=1 SV=2  ali   108...........................................................................................................................................................................................................................................................EVRSQFKLRACNSVFTALDHCHEAIEITSDDHVIQYVNPAFERMMGYHKGELLGKELADLPKSDKLDTINTCIKKGKEWQGVYYARRKS-QHVKITPVIGQGGKIRHFVSLKKLCCTTDNNKQIHKIHRDSGDNSQTEPHSFR---YKNRRKESIDVKSISSRGSDAPSLQNRRYPSM-ARIHSMT-IE........................................................................................................................................................................ 300
9 -12.000sp|Q12809|KCNH2_HUMAN Potassium voltage-gated channel subfamily H member 2 OS=Homo sapiens GN=KCNH2 PE=1 SV=1  ali   10  5...........................................................................................................................................................................................................................................................RGHVAPQNTFLDTIIRKFEGQSRKFIIANARVEVIYCNDGFCELCGYSRAEVMQRP--PRTQRRAAAQIAQALLGAEERKVEIAFYRK---LVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGA-VDLTPAAPSSESLALDEVTAMDN.......................................................................................................................................................................... 220
10 -11.600sp|Q8TE76|MORC4_HUMAN MORC family CW-type zinc finger protein 4 OS=Homo sapiens GN=MORC4 PE=1 SV=2  ali   15  50..........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................PFSAIAELLDNAV--DPDVSARTVFIDVEEVKNKSCLTFTDDGCGMTPHKLHRML-SFGFTDKVIKKPIGVFGNGF---KSGSMRLGKDALVFTKN-GGTLTVGLLSQTYLECVQAQA 163
11 -11.200sp|Q14149|MORC3_HUMAN MORC family CW-type zinc finger protein 3 OS=Homo sapiens GN=MORC3 PE=1 SV=3  ali   15  29..........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................PFSAVAELIDNAY--DPDVNAKQIWIDKTVINDHICLTFTDNGNGMTSDKLHKMLS---KVTMNGHVPVGLYGNGF---KSGSMRLGKDAIVFTKNGESMSVGL.............. 129
12 -11.100sp|O95263|PDE8B_HUMAN High affinity cAMP-specific and IBMX-insensitive 3`,5`-cyclic phosphodiesterase 8B OS=Homo sapiens GN=PDE8B PE=1 SV=2  ali   1......................................................................................................................................................................................................................................................................................................MMGYHKGELLGKELADLPKSDKLDTINTCIKKGKEWQGVYYARRKS-QHVKITPVIGQGGKIRHFVSLKKLCCTTDNNKQIHKIHRDKESIDVKSISSRGSDAPSTIEAPITKVINIINAAQENSPVTVAEALDRVLEILRTTELYSPQLGTKDEDPHTSDLVGGLMTDGLRRLSGNEYNVHQSHSHLAMPITINDVPPCISQLLDNEESWD-ELEAITHKRPLVYLGLKVRFGVCEF-LNCSETTLRA................................................................. 299
13 -10.900sp|Q9NS40|KCNH7_HUMAN Potassium voltage-gated channel subfamily H member 7 OS=Homo sapiens GN=KCNH7 PE=1 SV=2  ali   5...........................................................................................................................................................................................................................................................RGHVAPQNTFLGTIIRKFEGQNKKFIIANARVQIIYCNDGFCEMTGFSRPDVMQKPC-PETKRHDIAQIAQALLGSEERKVEVTYYHKN--NTHIIPVKNQEGVAMMFIINFEYVTDNENAARVNPILPIKTVNRKFPGLRVLTYRKQSLPQEDPDVVVIDSSKHSDDSVAMKHFKSPTKESCSPSEADDTKALIQPSKCSPLVNISGPLDHSSPKRQWDRLYPDMLQSS-------SQLSHSRSRESLCSIRRASSVHDIEGFGVHPKNIFRDRHASEDNG........................................................................... 300
14 -10.300sp|Q86VD1|MORC1_HUMAN MORC family CW-type zinc finger protein 1 OS=Homo sapiens GN=MORC1 PE=2 SV=2  ali   16  28..........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................LFGALAELLDNARDAGAERLDVFS-VDNEKLQGGFMLCFLDDGCGMSPEEASDIIYFGRSKKRLSTLKIGQYGNGL---KSGSMRIGKDFILFTKKE-ETMTCVFFSQTFCEEESLSE 141
15 -10.200sp|Q9Y6X9|MORC2_HUMAN MORC family CW-type zinc finger protein 2 OS=Homo sapiens GN=MORC2 PE=1 SV=2  ali   12  29..........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................LFGALAELVDNAR--DADATRIDIYAEREDLRGGFMLCFLDDGAGMDPSDAASVIQFGKSAKRTPESQIGQYGNGL---KSGSMRIGKDFILFTKKEDTMT................. 126
16 -9.830sp|A6NHR9|SMHD1_HUMAN Structural maintenance of chromosomes flexible hinge domain-containing protein 1 OS=Homo sapiens GN=SMCHD1 PE=1 SV=2  ali   11  32.....................................................................................................................................................................................................................................................................................................................................................................................DRREKESELGDRPLQVG-SDYAGFRACVCQGISPEEKFVITTTSRKEITCDNFDETVKDGVTLYLLQSVNQLLLTATKERIDFLPHY-----------DTLVKSGMYEYYASEGQNPLPFALAELIDNSLSATSRN-RIQIKLLFDETQGKPAVAVIDNGRGMTSKQLNNWAVRPVPVPRSLNSDISYFGVGG---KQAVFFVGQSARMISKPDSQDVHELVLSKEDFEKKEKNK 279
17 -9.670sp|Q9ULD8|KCNH3_HUMAN Potassium voltage-gated channel subfamily H member 3 OS=Homo sapiens GN=KCNH3 PE=2 SV=2  ali   5...........................................................................................................................................................................................................................................................RGLLAPQNTFLDTIATRFDGTHSNFVLGNAQVAVVYCSDGFCDLTGFSRAEVMQRGC-PDTSELVRQQIRKALDEHKEFKAELILYRKS-CLLDVIPIKNEKGEVALFLVSHKDISETKNRGGKGFNANRRRSRAVLYHLSGHLQKQPKGKHKLNKGVFGEKPNLPEYKVAAIRKSPFILLHCGALRATWDGFILLATLYVAVTVPYSVCVSTAREPSAARGPPSVCDLAVEVLFILDIVLNFRTTFVSKSGQVVFAPKSICL.............................................................................................. 300
18 -9.240sp|Q96RG2|PASK_HUMAN PAS domain-containing serine/threonine-protein kinase OS=Homo sapiens GN=PASK PE=1 SV=3  ali   13  115................................................................................................................................................................................................................................................................SSGWSSPLLPAPVCNPNKAIFTVDAKTEILVANDKACGLLGYSSQDLIGQKLTQFFLREEHMEADGHAAVVFGTVVDIISRSGEKIPVSVWMKRMRQERRLCCVVVLEPVERVSTWVAFQSD-VTSCDSLF----AHLHGYVSG--------EDVAGQHITDLIPSVQL-GQHIPKNLKIQRS......................................................................................................................................................................... 299
19 -9.010sp|O95744|PM2L2_HUMAN Putative postmeiotic segregation increased 2-like protein 2 OS=Homo sapiens GN=PMS2L2 PE=5 SV=1  ali follow..  10  7...................................................................................................................................................................................................................................................................................................................................................................................................KPPTPTPEGPTVSVKQLFSTLPVRHKEFQRNIKKKRACFPFAFCRDQFLEGSPAMLPVQPAKLTEPAKAIKPIDRKSVHQICSGPVV--------------LSLSTAVKKIVGNSL----DAGATNIDLKLKDYGMDL-IEVSGNGCGVEEENFEGLSLSALK-DLTRVETFGFQGKALSSLCALSDVHDGKIIKKTPYPRGTTVSVKLPVRHK....... 236

FFAS is supported by the NIH grant R01-GM087218-01
1 4 6 1 4 9   jobs submitted since Jan 1, 2011
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Friedberg I, Nika K, Tautz L, Saito K, Cerignoli F, Friedberg I, Godzik A, Mustelin T. Identification and characterization of DUSP27, a novel dual-specific protein phosphatase. FEBS Lett. 2007 May 29;581(13):2527-33. Epub 2007 Apr 30.