current user: public

If you have questions about the server, please let us know.

Query: gi|15923009|ref|NP_370543.1| two-component sensor histidine kinase (SAV0019) [Staphylococcus aureus subsp. aureus Mu50], from S.aureus

Results of FFAS03 search in SCOP207
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
    .   10    .   20    .   30    .   40    .   50    .   60    .   70    .   80    .   90    .  100    .  110    .  120    .  130    .  140    .  150    .  160    .  170    .  180    .  190    .  200    .  210    .  220    .  230    .  240    .  250    .  260    .  270    .  280    .  290    .  300    .  310    .  320    .  330    .  340    .  350    .  360    .  370    .  380    .  390    .  400    .  410    .  420    .  430    .  440    .  450    .  460    .  470    .  480    .  490    .  500    .  510    .  520    .  530    .  540    .  550    .  560    .  570    .  580    .  590    .  600    .
# Score Template Links and tools%idFirst MKWLKQLQSLHTKLVIVYVLLIIIGMQIIGLYFTNNLEKELLDNFKKNITQYAKQLEISIEKVYDEKGSVNAQKDIQNLLSEYANRQEIGEIRFIDKDQIIIATTKQSNRSLINQKANDSSVQKALSLGQSNDHLILKDYGGGKDRVWVYNIPVKVDKKVIGNIYIESKINDVYNQLNNINQIFIVGTAISLLITVILGFFIARTITKPITDMRNQTVEMSRGNYTQRVKIYGNDEIGELALAFNNLSKRVQEAQANTESEKRRLDSVITHMSDGIIATDRRGRIRIVNDMALKMLGMAKEDIIGYYMLSVLSLEDEFKLEEIQENNDSFLLDLNEEEGLIARVNFSTIVQETGFVTGYIAVLHDVTEQQQVERERREFVANVSHELRTPLTSMNSYIEALEEGAWKDEELAPQFLSVTREETERMIRLVNDLLQLSKMDNESDQINKEIIDFNMFINKIINRHEMSAKDTTFIRDIPKKTIFTEFDPDKMTQVFDNVITNAMKYSRGDKRVEFHVKQNPLYNRMTIRIKDNGIGIPINKVDKIFDRFYRVDKARTRKMGGTGLGLAISKEIVEAHNGRIWANSVEGQGTSIFITLPCEVIEDGDWDELast
1 -55.000d2c2aa2 d.122.1.3 (A:321-481) Sensor histidine kinase TM0853 {Thermotoga maritima [TaxId: 2336]}  ali model 3D-neighbors follow..  36  1............................................................................................................................................................................................................................................................................................................................................................................................................................................................QINREKVDLCDLVESAVNAIKEFASSHNVNVLFESNPVEAYIDPTRIRQVLLNLLNNGVKYSKKDADKYVKVILDEKDGGVLIIVEDNGIGIPDHAKDRIFEQFYRVDSSLTYEVPGTGLGLAITKEIVELHGGRIWVESEVGKGSRFFVWIPKDRA....... 161
2 -47.200d1bxda_ d.122.1.3 (A:) Histidine kinase domain of the osmosensor EnvZ {Escherichia coli [TaxId: 562]}  ali model 3D-neighbors follow..  27  4............................................................................................................................................................................................................................................................................................................................................................................................................................................................EMPMEMADLNAVLGEVIAAESGYERE--IETALYPGSIEVKMHPLSIKRAVANMVVNAARYG--NGWIKVSSGTE--PNRAWFQVEDDGPGIAPEQRKHLFQPFVRGDSARTI--SGTGLGLAIVQRIVDNHNGMLELGTSERGGLSIRAWLPVPVTRAQGTTK 159
3 -46.400d1ysra_ d.122.1.3 (A:) automated matches {Mycobacterium tuberculosis [TaxId: 1773]}  ali model 3D-neighbors follow..  21  2..............................................................................................................................................................................................................................................................................................................................................................................................................................................................DHVPVDITDLLDRAAHDAARIYPDLDVSLVPSPT-CIIVGLPAGLRLAVDNAIANAVKHGGAT---LVQLSAVSSRAGVEIAIDDNGSGVPEGERQVVFERFSRGSTASH---SGSGLGLALVAQQAQLHGGTASLENSPLGGARLVLRLPGPS........ 148
4 -45.200d1id0a_ d.122.1.3 (A:) Histidine kinase PhoQ domain {Escherichia coli [TaxId: 562]}  ali model 3D-neighbors follow..  24  2................................................................................................................................................................................................................................................................................................................................................................................................................................................................ELHPVAPLLDNLTSALNKVYQRKGVNISLDSPEISFVGEQNDFVEVMGNVLDNACKYCLE----FVEISARQTDEHLYIVVEDDGPGIPLSKREVIFDRGQRVDTLRP----GQGVGLAVAREITEQYEGKIVAGESMLGGARMEVIFGRQH........ 146
5 -40.900d2c2aa1 a.30.2.1 (A:232-320) Sensor histidine kinase TM0853 {Thermotoga maritima [TaxId: 2336]}  ali model 3D-neighbors follow..  29  2.....................................................................................................................................................................................................................................................................................................................................................................ENVTESKELERLKRIDRMKTEFIANISHELRTPLTAIKAYAETIYNSLGEDLSTLKEFLEVIIDQSNHLENLLNELLDFSRLERKSL.................................................................................................................................................................... 89
6 -39.900d2e0aa2 d.122.1.0 (A:188-386) automated matches {Human (Homo sapiens) [TaxId: 9606]}  ali model 3D-neighbors follow..  19  2........................................................................................................................................................................................................................................................................................................................................................................................................................................SHIGSIDPNCDVVAVVQ----------DAFECSRMLCDQYYLSSPELKLTQKFPDQPIHIVYVPSHLHHMLFELFKNAMRATVEHQENQIEVIVVLGKEDLTIKISDRGGGVPLRIIDRLFSYTYSMDNSRNAPLAGFGYGLPISRLYAKYFQGDLNLYSLSGYGTDAIIYLKALSSESIE... 186
7 -35.400d1r62a_ d.122.1.3 (A:) Nitrogen regulation protein NtrB, C-terminal domain {Escherichia coli [TaxId: 562]}  ali model 3D-neighbors follow..  24  1...............................................................................................................................................................................................................................................................................................................................................................................................................................................................RVTESIHKVAERVVTLVSMELPDNRLIRDYDPSLPELAHDPDQIEQVLLNIVRNALQLGPEGGEIILRTRTERYRLAARIDVEDNGPGIPPHLQDTLFYPMV------SGREGGTGLGLSIARNLIDQHSGKIEFTSWPG-HTEFSVYLPIRK........ 156
8 -32.700d4e01a2 d.122.1.4 (A:186-375) Branched-chain alpha-ketoacid dehydrogenase kinase (BCK) {Norway rat (Rattus norvegicus) [TaxId: 10116]}  ali model 3D-neighbors follow..  20  9.................................................................................................................................................................................................................................................................................................................................................................................................................................................................RLSPKKIIEKWVDFARRLCEHKAPRVRINGHAARFPFIPMPLDYILPELLKNAMRATMESHLDTVVITIANNDVDLIIRISDRGGGIAHKDLDRVMDYHFTTSGGQSGPMHGFGFGLPTSRAYAEYLGGSLQLQSLQGIGTDVYLRLR........... 186
9 -27.700d2hkja3 d.122.1.2 (A:10-228) Topoisomerase VI-B subunit {Sulfolobus shibatae [TaxId: 2286]}  ali model 3D-neighbors follow..  16  7..........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................FKRNPELAGFPNPARALYQTVRELIENSLDATDVHGNIKITIDLDDARQIYKVNVVDNGIGIPPQEVPNAFGRVLYSSKYVNRQTGMYGLGVKAAVLYSQMHQDKIEIETSPNSKRIYTFKLKIDINKNE.... 143
10 -22.700d1th8a1 d.122.1.3 (A:1-136) Anti-sigma factor spoIIab {Bacillus stearothermophilus [TaxId: 1422]}  ali model 3D-neighbors follow..  17  36......................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................ELTEIKTVVSEAVTNAIIHGDPNGIVSISVIIED--GVVHLTVRDEGVGIP--DIEEARQPLF----TTKPELERSGMGFTIMENFM----DEVIVESEVNKGTTVYLK............. 135
11 -18.100d1i58a_ d.122.1.3 (A:) Histidine kinase CheA {Thermotoga maritima [TaxId: 2336]}  ali model 3D-neighbors follow..  20  2...............................................................................................................................................................................................................................................................................................................................................................................................................................................................SHMVPISFVFNRFPRMVRDLAKKMNKEVNFIMRGEDTELDRTFVEEILLHLLRNAIDHKPPIGTLILSARHE--GNNVVIEVEDDGRGIDKEKIIRLFVPGFSTKEKVS-EVSGRGVGMDVVKNVVESLNGSISIESEKDKGTKVTIRLPLT......... 189
12 -14.800d1ixma_ d.123.1.1 (A:) Sporulation response regulatory protein Spo0B {Bacillus subtilis [TaxId: 1423]}  ali model 3D-neighbors follow..  1..............................................................................................................................................................................................................................................................................................................................................................................SDTALTNEL--HLLGHSRHDWMNKLQLIKGNLSL--------------------QKYDRVFEMIEEMVIDAKHESKLSNLKTPH------LAFDFLTFNWKTHYMTLEYEVLGEIKDLSAYDQKLAKLMRKLFHLFDQAVSSENHLTVSLQTDHPDRQLILYLDFHGAFADPSAFDDIRQNGYEDVDIMRFEITSHECLIEI........................................ 177
13 -13.800d1nwza_ d.110.3.1 (A:) Photoactive yellow protein, PYP {Methylophilus methylotrophus, strain w3a1 [TaxId: 17]}  ali model 3D-neighbors follow..  11  1......................................................................................................................................................................................................................................................MEHVAFGSEDIENTLAKMDDGQLDGLAFGAIQLDGDGNILQYNAAEGDITGRDPKQVIGKNFFKDVAPCTDSPEFYGKFKENTMFEYTFDYQMTPTKVKVHMKKALSGD--SYWVFVKRV.................................................................................................................................................................................................................................................. 125
14 -11.700d5b1na_ a.30.2.1 (A:) automated matches {Escherichia coli [TaxId: 562]}  ali model 3D-neighbors follow..  25  4.......................................................................................................................................................................................................................................................................................................................................................................................RTLLMAGVSHDLRTPLTRIRLATEMM-------SEQDGYLAESINKDIEECNAIIEQFIDYLR.......................................................................................................................................................................... 59
15 -10.100d1v9ya_ d.110.3.2 (A:) Direct oxygen sensor protein, DOS {Escherichia coli [TaxId: 562]}  ali model 3D-neighbors follow..  15  1......................................................................................................................................................................................................................................................................GIFFPALEQNMMGAVLINENDEVMFFNPAAEKLWGYKREEVIGNNIDMLIPRDHNREGGKARVEGMSRELQLEKKDGSKIWTRFALSKVSAEGKVYYLALVRD................................................................................................................................................................................................................................................... 113
16 -10.000d3sw1a_ d.110.3.0 (A:) automated matches {Pseudomonas putida [TaxId: 160488]}  ali model 3D-neighbors follow..  16  3....................................................................................................................................................................................................................................................................NAQLLQSMVDASNDGIVVAEDDTILIYVNAAFEYLTGYSRDEILYQDCRFLRDQLGRARIRKAMAEGRPCREVLRNYRK---ELSITPVKSDFDQRTYFIGIQKDVSRQVELERELAELRA................................................................................................................................................................................................................................... 134
17 -10.000d2gj3a_ d.110.3.0 (A:) automated matches {Azotobacter vinelandii [TaxId: 354]}  ali model 3D-neighbors follow..  13  2....................................................................................................................................................................................................................................................................LPEIFRQTVEHAPIAISITDLKANILYANRAFRTITGYGSEEVLGKNESILSNGTTPRLVYQALWGRGVLVNRRKDKTLYLAELTVAPVLNEAGETIYYLGMHRDTSELH.............................................................................................................................................................................................................................................. 119
18 -9.150d2vv6a_ d.110.3.2 (A:) Histidine kinase FixL heme domain {Bradyrhizobium japonicum [TaxId: 375]}  ali model 3D-neighbors follow..  14  1...............................................................................................................................................................................................................................................................................IPDAMIVIDGHGIIQLFSTAAERLFGWSELEAIGQNVNILMPEPRYRTTSDPHIIGIGRIVTGKRRDGTTFPMHLSIGEMQSGGEPYFTGFVRDLT................................................................................................................................................................................................................................................. 106
19 -9.090d1ll8a1 d.110.3.5 (A:8-114) N-terminal PAS domain of Pas kinase {Human (Homo sapiens) [TaxId: 9606]}  ali model 3D-neighbors follow..  17  1................................................................................................................................................................................................................................................................................NKAIFTVDAKTEILVANDKACGLLGYSSQDLIGQKLTQFFLRSEHMEADGHAAVVFGTVVDIISRSGEKIPVSVWMKRMRQERRLCCVVVLEPVER................................................................................................................................................................................................................................................ 107

FFAS is supported by the NIH grant R01-GM087218-01
1 4 5 8 9 5   jobs submitted since Jan 1, 2011
Comments and questions to: webmaster

Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Slabinski L, Jaroszewski L, Rychlewski L, Wilson IA, Lesley SA, Godzik A. XtalPred: a web server for prediction of protein crystallizability. Bioinformatics. 2007 Dec 15;23(24):3403-5. Epub 2007 Oct 5.