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Query: gi|6319259|ref|NP_009342.1| Protein of unknown function, localized in the nucleoplasm and the nucleolus, genetically interacts with MTR2 in 60S ribosomal protein subunit export; Ecm1p (YAL059W) [Saccharomyces cerevisiae], from S.cerevisiae

Results of FFAS03 search in COG1018
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MWEQRRQKVVFSLTILVRYRLKQSMAKKISKNSRAARQSDALEPEVKDLSELPRAEKTDLTNILIRTAAKNEALLEAKISKKANKSKRGKKLNKKALEDKLDNSISSMDRDRLVKALNFTNRLDGKIAKSISRAKYIQNTRKAGWDSTNETIKKELAFLNGGLSVQAKSASEGNAEKEDEEIPEVFDSLAEDNTVQKTPTNRFGVLPDDVEELast
1 -7.050[S] KOG2890 Predicted membrane protein  ali follow..  14  293..ERRRQKALKELNDLNKTRTAEVASYGNWDDGDDDEPTEVTVVAPPPVSNVHSSKPAMDKESM.................................................................................................................................................... 355
2 -6.980[K] KOG3119 Basic region leucine zipper transcription factor  ali follow..  14  243.WDRRR------------------RNNEAAKRSREKRRYNDMVLEQRVIE----TKENHVLKAQLDAIRDKFNISGEN...................................................................................................................................... 298
3 -6.830[R] KOG3187 Protein tyrosine phosphatase-like protein PTPLA (contains Pro instead of catalytic Arg)  ali follow..  10  202MIGQRKKI----LGGGSKKKQLIATNQNSTLFINYSPKTKRQWKCFSAEFVDILCSPFGIFVIVIREESWKSNI.......................................................................................................................................... 271
4 -6.090[A] KOG3322 Ribonucleases P/MRP protein subunit  ali follow..  15  45..ESRSFEI--ALQDAMKRSKESSAQRAFQALPRCLRRRAASHNIKRIPKGLRDRALYEMQLSSSSTLPIAPSRQRLKRFIKRLRRKLAKSGETKAIDSTGSLVTDNSTDDSRIPSLAAVKLIRGKFAGRQLRKVWLPT-----WVC................................................................. 185
5 -6.010[R] KOG0274 Cdc4 and related F-box and WD-40 proteins  ali follow..  412VVNTRTEDIYLNEVAMV-VGSASGYCGVYDTVTGNFLKKIASARNAARREPINCILLDSNPLSLKGVITMSKHVKSWSYTIPKPFVNKRSKVLPLRPSVTHDNLSKSSDYSKNEVEREIMLGLDQIAQERREKMEARQKFEQHF-EIIAYVTMLSQEEEAKRMVQLSMDVDKIEEDFKENDEQATSSLNALSSNHEPPQEQANVAELNEQEQ 650
6 -5.980[S] COG5291 Predicted membrane protein  ali follow..  202.....................................................................STPCWVKKLFNEHPSSCCKARKGITIREGRERHERNMGYSNASTTSGDSMASLTDMADTKSSTENSAVTEESQCCAESFKDSSVVSSQKSMAVSTVVGSSTEAKNNYLDFTEALCDKEVVAEQNPESQSNEEWDEKWGDSDNE 344
7 -5.930[P] COG0619 ABC-type cobalt transport system, permease component CbiQ and related transporters  ali follow..  131....RSASILSLGLLMCWTTDSRDMLNGLVGLKVPYSAAFMVVTAVRFLPIIITEVLTVVTVQRLRGFNPKRFGS--------------------GIVKTSLNILTPTLSNCVRRTGTLAVSIQSRAFRANPDRTYLKKLKFSEFDKA................................................................ 254
8 -5.910[S] COG4905 Predicted membrane protein  ali follow..  10  90LWDYSTLPLFWGVGCIILIKLVNPP--------------------VQNWIHDFNELTHSWGVILILIIFLADLVSTFIFTISTKKEVLAMIDDSDKENAAIKEFCLKHLFANHETAANRIKVLELLKNKPLKLKHYNLRRILKNYPNMNLTKKR.......................................................... 235
9 -5.800[S] KOG4811 Uncharacterized conserved protein  ali follow..  15  1...............MAKSLRSKWKRK------RAEKRKKNAPKEASRLKSI................................................................................................................................................................ 32
10 -5.780[PT] KOG3676 Ca2+-permeable cation channel OSM-9 and related channels (OTRPC family)  ali follow..  11  697IWKLQRAITIL---DTEKSFLKCMRKAFRSGKLLQVGYTPDGKDDYRWCFRVDEVNWTTWNTGIINEDPGNCEGVKRTLSFSLRSSRVSGRHWKNFALVPLLREASARDRQSAQPEEVYLRQFSGSLKAEVFKSPAASGEK....................................................................... 839

FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Sikora S, Godzik A. Combination of multiple alignment analysis and surface mapping paves a way for a detailed pathway reconstruction--the case of VHL (von Hippel-Lindau) protein and angiogenesis regulatory pathway. Protein Sci. 2004 Mar;13(3):786-96. Epub 2004 Feb 06.