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Query: gi|7839146|ref|NP_058136.1| Putative protein of unknown function; YAL064C-A is not an essential gene; Yal064c-ap (YAL064C-A) [Saccharomyces cerevisiae], from S.cerevisiae

Results of FFAS03 search in COG1018
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MTGYFLPPQTSSYTFRFAKVDDSAILSVGGDVAFGCCAQEQPPITSTNFTINGIKPWQGRLPDNIAGTVYMYAGFYCPMKIVYSNAVSWHTLPVSVELPDVTTVSDDFAGHVYSFDDDLTAQLYYPLast
1 -8.760[S] COG4402 Uncharacterized protein conserved in bacteria  ali follow..  12  153........NVGEYDIVVLSAKESGGLWLNRNGYKIPRGAKQLLKPYIRSSMKFFVAKVNLDKFEQSGYQFLSSKFMLPIRLGMINATTEQDLIVYVLSPKGQAEITNYRTVKIPSN.......... 270
2 -7.400[T] KOG2397 Protein kinase C substrate, 80 KD protein, heavy chain  ali follow..  394LKDKCFDRNVQQYTYQFCPFGQNTQ---YSGTSLGSFKEWSGPEGNKYSKMHFGDGQQCWNGPKRSTDITIECGE----ELVEVTEPAKCEYLFTFRTP........................... 492
3 -7.270[S] COG4719 Uncharacterized protein conserved in bacteria  ali follow..  1.....MFPGGTTVKTHLTLTALALTSVSFAAQAAPAATSPIKLSGATYSVAQVTENGKTTERLVDASGKGALPGSLLQMTQKVQNVSARSVNGLRLNMDPATIYQSATCD................ 107
4 -6.880[R] COG3943 Virulence protein  ali follow..  11  1MSIILYTANDGTAQFALQEFGGQ--LWLTQADMAELYQTTKQNISKHIKTILAEQELEEKATVNFQLTVQNENGRKVNRKIAHYSLPMIIAVGYRVRSARGIQFRQWATERLDEY........... 113
5 -6.380[S] KOG4806 Uncharacterized conserved protein  ali follow..  433IQWIRAHDSHVKYCVYRRREHSNFLEHLVSLADNLCEGGLSSSVLVGCYTHSPTSSEDDAQSLIETTIGGLLPASTYRLDLLATPLDRPNAQALPFRT............................ 530
6 -6.270[Q] KOG1263 Multicopper oxidases  ali follow..  10  139GFGGLRVNSRLLIPVPYADPEDDYTILINDKSHTQLKKFLDSGRTIGRPDGILINGKSGKTDGSDKPLFTLKPGKTYRVRIC--NVGLKASLNFRIQNHKMKLVEME................... 246
7 -6.160[UO] KOG4434 Molecular chaperone SEC63, endoplasmic reticulum translocon component  ali follow..  10  441...FPAPGKPGNYQYTVFLRSDS---YMGLDQIKPLKLEVHEAKPVPENHPQWDTAIEGDEDQEDSEGFEDSFEE................................................... 509
8 -5.890[J] COG0089 Ribosomal protein L23  ali follow..  12  19.KATMSAEKSNTIVFKVAKDATKKEIKAAVEKLFE-VEVKSVNTLIIKGKTKRQGLRQGRRSDVKKAYVTLNEGQDLDF............................................... 95
9 -5.830[R] COG3541 Predicted nucleotidyltransferase  ali follow..  11....ILIGLAGSYGLNRPDSDDFRGVFIAPKRYYLGFDHIEQKDAGWDEPGIFPLLDGNKDTVIYELRKILQGANPNVLELLWLN-------EYPVLTDVGQYLINHRKLFLSK............ 119
10 -5.810[S] COG4676 Uncharacterized protein conserved in bacteria  ali follow..  19  180TTGYTPTPQKGPYLVYVN--------YFGGGYGSSEDGAEQAAQDLTTARITLVTEEGTPNEKQETFLVPMRKGELTLV--------------KRFSYP........................... 263

FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Sikora S, Godzik A. Combination of multiple alignment analysis and surface mapping paves a way for a detailed pathway reconstruction--the case of VHL (von Hippel-Lindau) protein and angiogenesis regulatory pathway. Protein Sci. 2004 Mar;13(3):786-96. Epub 2004 Feb 06.