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Query: gi|6319256|ref|NP_009339.1| NADP(+)-dependent glutamate dehydrogenase, synthesizes glutamate from ammonia and alpha-ketoglutarate; rate of alpha-ketoglutarate utilization differs from Gdh1p; expression regulated by nitrogen and carbon sources; Gdh3p (YAL062W) [Saccharomyces cerevisiae], from S.cerevisiae

Results of FFAS03 search in CSGID
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MTSEPEFQQAYDEIVSSVEDSKIFEKFPQYKKVLPIVSVPERIIQFRVTWENDNGEQEVAQGYRVQFNSAKGPYKGGLRFHPSVNLSILKFLGFEQIFKNALTGLDMGGGKGGLCVDLKGKSDNEIRRICYAFMRELSRHIGKDTDVPAGDIGVGGREIGYLFGAYRSYKNSWEGVLTGKGLNWGGSLIRPEATGFGLVYYTQAMIDYATNGKESFEGKRVTISGSGNVAQYAALKVIELGGIVVSLSDSKGCIISETGITSEQIHDIASAKIRFKSLEEIVDEYSTFSESKMKYVAGARPWTHVSNVDIALPCATQNEVSGDEAKALVASGVKFVAEGANMGSTPEAISVFETARSTATNAKDAVWFGPPKAANLGGVAVSGLEMAQNSQKVTWTAERVDQELKKIMINCFNDCIQAAQEYSTEKNTNTLPSLVKGANIASFVMVADAMLDQGDVFLast
1 -110.000IDP02649 putative glutamic dehyrogenase-like protein [Salmonella typhimurium LT2] STM1795 [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]  ali follow..  28  26.DSSTSAWNTYLQQIERV-----APYLGELSPWVDTLRHPKRALIVDIPVQMDDGTIRHFEGYRVQHNLSRGPGKGGVRYHPDVDLNEVMALSAWMTIKCAALNLPYGGAKGGIRVDPFSLSEGELERLTRRYTSEIGIIIGPQKDIPAPDVGTNGKVMAWMMDTYSMNHGTVTGVVTGKPIHLGGSLGREKATGRGVFVSGLEAARR---ANIAVEGARVAVQGFGNVGSEAARLFAGAGARVVAIQDHTATLFNATGIDMKALTAWQTEHKQIAGFPG--------------AETIASDAFWRLEMDILIPAALEGQITRQRAEALTCKLV---LEGANGPTYPDADDVLA---------SRGILVVPDVVCNAGGVTVSYFEWVQDMASFFWSEEEINARMDKIMTDAIVHVWEKAAEKS--------CSLRTAAYIVACERILLARKDRGIY. 439
2 -106.000IDP92108 NADP-specific glutamate dehydrogenase, putative [Toxoplasma gondii ME49] TGME49_093180 [Toxoplasma gondii ME49]  ali follow..  51  57.RFQPEFLQAFHEVFDSV--RPVLCSNPKYLRAFKVIVEPERCITFRVPWVDDQGKQHVSRGYRVQYSSAAGPYKGGLRFHPSVTLSVMKFLGFEQIFKNSLTGLSIGGAKGGSDFDPKGRSDNEVMRFCQAFMTELSRYIGPNRDVPAGDIGVGAREIGYLFGQYKLLKAQFEGALTGKDKNWGGSAMRPEATGYGCVYFVLELLKAQN--KEGIKGMRCAISGSGNVALYAGEKLATLGAKVMTFSDSSGYIVNEKGFPLGQIQRLKEMKETRSSTR-----VSEFAAKYSTVKFVPDKRAWEVPCDIAFPCATQNEISEEDAQLLIDNGCRIVAEGANMPTTRDAIRLFK---------QHGVILCPGKAANAGGVAVSGLEMSQNAMRIEWTREVVDEKLRQIMASIFSKCRSYAAKFG-----ENEFDLVTGANVAGFVKVADCVIDQGYI. 489
3 -105.000IDP02337 gene: gdhA; glutamate dehydrogenase [Bacillus anthracis str. `Ames Ancestor`] GBAA1511 [Bacillus anthracis str. `Ames Ancestor`]  ali follow..  27  12QQQREQHFELLNSTQIVISEAL--EKLGYPNEVYELLKEPIRMMTVKIPVRMDDGTVKIFTGYRAQHNDAVGPTKGGIRFHPNVTENEVKALSIWMSLKCGIVDLPYGGGKGGIICDPREMSFRELERLSRGYVRAISQIVGPTKDIPAPDVFTNSQIMAWMMDEYSRIDENSPGFITGKPLVLGGSHGRETATAKGVTICIREAAKK---RDIDIKGARVVVQGFGNAGSFLAKFMHDAGAKVIAISDAYGALHDPNGLDIDYLLDRRDSFGTVTKL---------------FNNTISNKELLELDCDILVPAAIENQITEENANDIKAKIV---VEAANGPTTLEATKILT---------DRGILLVPDVLASAGGVTVSYFEWVQNNQGYYWTEEEVEQRLEKVMVRSFDSIYETAQVRK--------VNMRLAAYMVGVRKMAEASRFRGWV. 428
4 -33.900IDP91367 NAD-specific glutamate dehydrogenase [Vibrio vulnificus CMCP6] VV1_2638 [Vibrio vulnificus CMCP6]  ali follow..  12  1........................................................................................MLGLVKAQQVKNT--VIVPVGAKGGFVCKRQHTMTAEGQRCYKRFIRALLDVSDNIIE-DPYLVVAADKGTATFSDLANSVSAEYDAFASGGSN--GYDHKAMGITAKGGWESVKRHFREMGI---DCQTTDFTAIGVGDMAGDVFGMLLSKHIRLQAAFNHLHIFIDPNPDSASSWEERDRLTPEIQKMLGTKKTSLAPNELIKMILKMDVDLLWNGGIGTYVKASSENDVLRIDGRDLNAKVV---GEGGNLGMTQKGRIEYA---------LKGGRVNTDFVDNVGGVDCSDNEVNIKIFLNGLTVKQRNKILESMQDEVGDIVLDDAYRQSESISVT---EQQGVSVVKEQIRFIHTMEKAGYL. 420
5 -8.940IDP02330 gene: ilvC-1; ketol-acid reductoisomerase [Bacillus anthracis str. `Ames Ancestor`] GBAA1419 [Bacillus anthracis str. `Ames Ancestor`]  ali follow..  15  1.........................................................................................................................................................................................................MAKVYYEKDVTVNVLKEKKVAIIGYGSQGHAHAQNLRDNGFDVVVRKGKSWDKAKEDGFSVYTVAEAAK------------------------------------QADVVMILLQPEVYEEEIAPNLQAGNSLVFAHGFN--KPPVNVDVFLVAPKGPGHLVRRTFS-------EGGAVPALFAVYQDATG---VATEKALSYADGIGATRAGVLETTFKEETETDLFGEQAVLCGGVTALVKAGFETLVDAGY.. 218
6 -8.230IDP02524 gene: ilvC-2; ketol-acid reductoisomerase [Bacillus anthracis str. `Ames Ancestor`] GBAA1852 [Bacillus anthracis str. `Ames Ancestor`]  ali follow..  13  2...........................................................................................................................................................................................................KTYYEQDANVGLLQGKTVAVIGYGSQGHAQAQNLRDSGVEVVVRPGKSFEVAKADGFEVMSVSEAVR------------------------------------TAQVVQMLQQAHVYKAEVEENLREGQMLLFSHGFN--NPPSYVDVAMVAPKSPGHLVRRVFQ-------EGNGVPALVAVHQDATG---TALHVALAYAKGVGCTRAGVIETTFQEETETDLFGEQAVLCGGVTALVKAGFETLTEGGY.. 217
7 -7.700IDP90757 gene: ilvC; ketol-acid reductoisomerase [Campylobacter jejuni subsp. jejuni NCTC 11168] Cj0632 [Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819]  ali follow..  12  4...........................................................................................................................................................................................................TVYYDKDCDLNLIKSKKVAIIGFGSQGHAHAMNLRDNGVNVTIGLSVSAVKAKNAGFEVVSVSEASK------------------------------------IADVIMILIQADIFNVEIKPNLSEGKAIAFAHGFN----------IHYGQIVVPKGVDVIMIAPK-EFTLGGGTPCLIAIHQDESK---NAKNLALSYASAIGGGRTGIIETTFKAETETDLFGEQAVLCGGLSALIQAGFETLVEAGY.. 220
8 -7.510IDP01873 gene: maeA; malate dehydrogenase [Francisella tularensis subsp. tularensis SCHU S4] FTT0917 [Francisella tularensis subsp. tularensis SCHU S4]  ali follow..  8  132.............................QSGLFISISHKKHIARILERYEYNSIDLVLVTGEAVLGIGDQGIGGMNI---SIGKIMVYVAASGIDPARVLPVQLDMGTNNDALLNAPGYLGVRLPRVSGETYDEFIEEFV-PNVFLHWEDLGRDN-----ILEKYKDKLCTFNDDIEGTGVATANCIAGVKTASTIR---INAGEITVEEALSGICDIKVVIFGAGSAGCGIARQLADVIADRAGVSIEKARLVDRYGLVCDRLRAKRITPEQKLFVKTREEIDKWKVEDFNYITLE--ETVKNTKCDILIGTSQPGSFTKEIIKTMAKNNNYPIIMPLSNPTSTNGKALIAAGSPFPDVTYNGRDYRISQGNNA-GLGLGSVA----------HARVLTKGMIRAASYRLSELSPMVINEDITQPLLARITDLVDVTKEITKAVAKQAILEGV.. 566
9 -6.860IDP02522 gene: hemA; glutamyl-tRNA reductase [Coxiella burnetii RSA 493] CBU_1966 [Coxiella burnetii RSA 493]  ali follow..  12  8................................................................INHQSAPLTVREKLVFTPERTPLALQSLLAEKAVNEALLLSTCNRTEIYTTVDEAATILRWLSKQPQLSGIDLRSFCGLDSMVLGEPQILGQMKQAYLLARRIGAVGSELGRLFPAVFAATKRIRSETAIGANPVSIAYAVVQLAKRIFSHLNQCQILLIGAGETIELVFSHLYNQGARHFFIANRTAEPYHAQAIRLSDIPTYLPKVDIVISATMSQLPLVGKGAVESALRQRKRRPLF---ADLALPRDIEPETAQEDVYLYNIDDLQTLIAQTREAAAKQAEAMVEMQAIHYMRQLQVHKAGDTIRRFRERVEMLRDQELEKALAHFQRTNDPKAVIAHFAHNLTNKILH........................................ 386
10 -6.860IDP02777 gene: hemA; glutamyl-tRNA reductase [Bacillus anthracis str. `Ames Ancestor`] GBAA4698 [Bacillus anthracis str. `Ames Ancestor`]  ali follow..  11  8................................................................VNYRTAPVEFREKLTFQAAELERAMTTLQNQKSVLENVIVSTCNRTEIYAVVDQLHTGRYYIKKFLADWFGAIDHLFRVTCGLDSMVVG-ETQILGQIKDSFLEAQGTIFNELFKQVITLAKRAHSETTIGESAMSVSYAAVELGKKIFGELTDCHVLILGAGKMGELALQNLYGSGARKVTVMNRTAEKYMGHAKPLSELQCALLEADILISSTGASDYVITKEMMTKVEKMRSGRPLF---VDIAVPRDIDPAIDEEGSFLYDIDDLQGVVEAERLKEAEKIQFMIEEEIVLFKTWLSTLGVVPLISARDKALAIQSETMESLERKIPNLSDRERKVISKHTKSIINQLLK........................................ 391
FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Rychlewski L, Zhang B, Godzik A. Functional insights from structural predictions: analysis of the Escherichia coli genome. Protein Sci. 1999 Mar;8(3):614-24.