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Query: gi|6319260|ref|NP_009343.1|(removed signalp:1-19) Calnexin; integral membrane ER chaperone involved in folding and quality control of glycoproteins; chaperone activity is inhibited by Mpd1p, with which Cne1p interacts; 24% identical to mammalian calnexin; Ca+ binding not yet shown in yeast; Cne1p (YAL058W) [Saccharomyces cerevisiae], from S.cerevisiae

Results of FFAS03 search in CSGID
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst TSLLSNVTLAEDSFWEHFQAYTNTKHLNQEWITSEAVNNEGSKIYGAQWRLSQGRLQGSAWDKGIAVRTGNAAAMIGHLLETPINVSETDTLVVQYEIKLDNSLTCGGAFIKLMSGFMNVEALKHYAPDTEGVELVFGPDYCAPEINGVQFAINKVDKITHESKLRYLQEMPLSKLTDTSQSHLYTLIIDESAQSFQILIDGKTVMVREHIEDKKKVNFEPPITPPLMIPDVSVAKPHDWDDRIRIPDPEAVKLSDRDERDPLMIPHPDGTEPPEWNSSIPEYILDPNAQKPSWWKELEHGEWIPPMIKNPLCTAERGCGQQIPGLINNAKYKGPGELNEIINPNYMGEWHPPEIENPLYYEEQHPLRIENVISGVILEFWSGSPNMLISNIYVGKNVTEAQIIGNKTWLMRDRAFRGSDGPTERKFMNSRLGNLQTTFHNERESPNPFDRIIDRILEQPLKFVLTAAVVLLTTSVLCCVVFTLast
1 -6.100IDP91976 hypothetical protein HMPREF0837_10616 [Streptococcus pneumoniae TCH8431/19A] HMPREF0837_10616 [Streptococcus pneumoniae TCH8431/19A]  ali follow..  12  44EVQYQQRDTKNLVENGDFGQTEDGSS-AQGW---------SAWVDQKNSSADASTRVIEAKDGAITISSPEKL---RAAVHRMVPIEAKKKYKLRFKIKTDN----GIAKVRIIEGK.............................................................................................................................................................................................................................................................................................................................................................................. 151
2 -4.730IDP01021 gene: yaaY; putative cytoplasmic protein STM0044 [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]  ali follow..  16  1.............................................................................................MQHSLRSD-----GAGFYQLACCEYSLSMRKIALSGG------FWGGVCRMAMKSIFFMFHQGNRR.................................................................................................................................................................................................................................................................................................................................... 55
3 -4.440IDP06413 gene: vIRF-2; vIRF-2 [Human herpesvirus 8] YP_001129414 [Human herpesvirus 8]  ali follow..  10  6...........................ESEWLTDFIIDALDSGRFWGGW---------LDEQKRITVPGRNRRERMPEGFDD-FYEAFLEERRRHGLPEIPETETGLGCFGRLLRTA-------NRARQERPFTIYKGKMKCLVYLTQEP-ALFGIYPHDDKHREKALRRSLRKKAQREAARKQAAAVATPTTSSAAEVSSRSQSEDTESSDSENELWVGAQGFVGRDMHSLFFEEPEP-GQSSSLLAPDSPRPSTSQVQGPLHVHTPTDLCLPTGGLPSPVIFPHETQGLLA----PPAGQSQTPFSPEGPVPSHVSGLDDCLPMVDHIE........................................................................................................................................................ 317
4 -4.180IDP00202 putative membrane protein YPO2731 [Yersinia pestis CO92]  ali follow..  5  44.................................GLIRAYEHILSFDTHARFDADGSMEMRENIKVLSLGKQISRGIFRTLPLTWNRQDGKFFSVEYQI------------KNVLRDGVAEPFSVTKEGET--LMVRIGRADHILKPGIYNYVIQYQVSNHFSRFPDW--------------DELYWNVT---GNGWEYPISKASFH----------------LELPASEAFLNSEKDTRLSTIDVYTGRLGEKEQNAKILADGSVQTSQPLKQGEGLT-PRTILANAPAPETSSLLVYLLLPTVQTSVTAIGLKMPPIVPLYALPATLSPGYLRYVTQRKYDAIAFSS--------------------DLLNLVAQRVAIKTKKSKNKSPWVLNSRDEQWLSL--QSDGNQLDIHDKQLLHTLFSSNRKNINLSKPHQRPMQKALKFLEKRCEDQQEKLFSQWLGPIWRGIFIMLLVPVICGL 450
5 -4.160IDP90586 gene: cls; cardiolipin synthetase [Yersinia pestis CO92] YPO2188 [Yersinia pestis CO92]  ali follow..  8  119............................................................NQLQLLTTTDDTLKALVRDIELA-----RHNIEMVFYIWQPGGL--VDQVAESLMAAARRGVHCR---------LLL--DSAGSQFFRSPYPAMMRNAGIEVVEALKVNVFRMFLRRMDLRQHRKIVL-----------IDNYVAYTGSM-----------------NMVDPRDAGVGQWIDMMRMEGPVATT-CDWEIETGKRILPPPPDANIMPFEEETGHTIQVIASGPGFPEEMIHQALLT-AVYAAR----------EQLIMTTPYFPSDDLLHAICTAAQRGVDVSIIVPNDSMMVRWASRAFFTELLNAGVKIYQFEGGLLHSKSVLVDGQ--TVNLDMRSLWLNFEITLVIDDDGFGADLAQVQDDYIARSALLDGERWNKRPLWHRVTERLFYFFSPLL............... 486
6 -4.110IDP05039 conserved domain protein [Bacillus anthracis str. Ames] BA_2214 [Bacillus anthracis str. Ames]  ali follow..  10  36...........................................................................................................................................................EKQIQSIVSEQYPGKIKSMKLINKEEQDFYKVNLLNEQGSYEIIVDAK---NGEVKRAKEKSLKSNTITKEKAEEMALQKVQGEIKYTILEKRNEIEVFV--NDKQSKVVEIEKTTGQIQLLEKPMTKVTEEQAKD-----QQVPGN-----EKGIRLEQKNEKNIYVIEIEKNANENVIVEIEETTGAFIGTSQIQKVITEEQAKE---ALQKVQGGFIEKVSIVDINGTATYQIIIKKQTETVDVRVHTITGEIISTTSVNNTIQQKESSQQQDDDHQEESDDDQDDDDE.................................... 318
7 -4.100IDP05117 putative collagen-binding protein [Clostridium difficile 630] CD2831 [Peptoclostridium difficile 630]  ali follow..  11  3................................................................................................................................................................................KGNRKALLISLILSMVVSTIYPTVSYASELGENSQIQSGSTNSSTGEEKESDNKKPEQTPEKDKATDNKKPEQTPEEEKPTDNKKPEQTPEEDKSTDNKKPEQTPEGEKPIDNKKPEQIPEEDKSTDNKKSEQALE........................................................................................................................................................................... 140
8 -4.060IDP91497 hypothetical protein VP1683 [Vibrio parahaemolyticus RIMD 2210633] VP1683 [Vibrio parahaemolyticus RIMD 2210633]  ali follow..  12  200......................................................................................................................GNAPQLSTLQNIAKYVQNAKAGCCTTFAFAAAAEMIQGMSGT---PENQPKVEVVAFKKGHSGTHLYVLVGRQ--------------------------------------EGSDIKDPSTWNKDVKIVDP-------WAASA.............................................................................................................................................................................................................................. 294
9 -3.890IDP00404 gene: virG; needle complex outer membrane lipoprotein precursor YPCD1.48 [Yersinia pestis CO92]  ali follow..  14  13...............................LVGCATPPMPAQRIVGEVRMSRPLSRIAHIDVSMFGLYEGKVREVQRT--------ETGNLPLFFSIKLNP-AQRGEGELYLFPERGVQAVAQQKLTGKNKVVLQMIPKTCYPNCQ................................................................................................................................................................................................................................................................................................................................................ 126
10 -3.880IDP91733 P88946_HHV8 [Human herpesvirus 8 type M]  ali follow..  9  1...............................................................................................................................................................................................................................MDPGQRPNPFGAPGAIPKK----PCLSQGSPGTSGSGAPCDEPSRSESPGEGPSGTGGSAAAGDITRQAVVAAITEWSRTRQLRISTGASEGKASIKDWIVCQVNSGKFPGEWEDE--ERTRFRIPVTPLADPCFEWRRDGEL-----------GVVYIRERG----NMPVDASFKGTRGRRRMLAALRRTRGLQEIGKGISQDGHH..................................................... 187
FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Pawlowski K, Jaroszewski L, Rychlewski L, Godzik A. Sensitive sequence comparison as protein function predictor. Pac Symp Biocomput. 2000;:42-53.