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Query: gi|6319278|ref|NP_009361.1| Cytochrome c heme lyase (holocytochrome c synthase), attaches heme to apo-cytochrome c (Cyc1p or Cyc7p) in the mitochondrial intermembrane space; human ortholog may have a role in microphthalmia with linear skin defects (MLS); Cyc3p (YAL039C) [Saccharomyces cerevisiae], from S.cerevisiae

Results of FFAS03 search in CSGID
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MGWFWADQKTTGKDIGGAAVSSMSGCPVMHESSSSSPPSSECPVMQGDNDRINPLNNMPELAASKQPGQKMDLPVDRTISSIPKSPDSNEFWEYPSPQQMYNAMVRKGKIGGSGEVAEDAVESMVQVHNFLNEGCWQEVLEWEKPHTDESHVQPKLLKFMGKPGVLSPRARWMHLCGLLFPSHFSQELPFDRHDWIVLRGERKAEQQPPTFKEVRYVLDFYGGPDDENGMPTFHVDVRPALDSLDNAKDRMTRFLDRMISGPSSSSSAPLast
1 -6.790CPX_91722_91684 Complex of ROA1_HUMAN with Q19QW0_CVHSA [Undefined organism]  ali follow..  18  545...FYAEGSRGGSQASSRSSSRSRG---NSRNSTPGSSRGNSPARMASGDRLNQLESKVSGKGQQQQGQTVTKKSAAEASKKPRQKRTATK-QYNVTQAF-----RRGPEQTQGNFGDQDL-----IRQGTDYKHWPQIAQF----------APSASAFFGMSREVTPSGTWLTYHGAI---KLDDKDPLNKH---IDAYKTFPPTEPKKDKKKK---EAQPLPQRQKKQPTVTL---PAAD-----MDDFSRQLQNSMSGASADST.. 793
2 -6.500IDP92122 DNA-directed RNA polymerase alpha chain, putative [Toxoplasma gondii ME49] TGME49_049560 [Toxoplasma gondii ME49]  ali follow..  16  658......AAGSAASDGGMEKDAKPSVWPVPGRGLGNEIFVASSP-QEEEMMRGDTLREKKEAAARTLDLEQTRLQQHIPEGLGPRSGPTYGLSERDLDERLLD-----------EEEEEERIVNTSAIIRKEREEAWKDKQR-ENEPLKQLGDGKGLVRYPPDTKPMM-------------------EAP----EWVME--------------------DPM-GQRKPIGFSEFNDD................................. 836
3 -5.940IDP90641 gene: birA; biotin--protein ligase [Campylobacter jejuni subsp. jejuni NCTC 11168] Cj0099 [Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819]  ali follow..  7  17....................................................STHLFLCKQIRNGKIDENFAIYALEQING---VGSRENSWQSSKGNLHLSFCIKEEDLPKDLPLASVSIYFAYLLKEVLQEKGSKIWLKWPN............................................................................................................................. 105
4 -5.710IDP90115 kelch-like protein [Monkeypox virus] MPXV_ZAI1979_005_024 [Monkeypox virus]  ali follow..  12  30........................................................................IKNSDYIFTITHYSPRTEYWTINTDRQFYDANVLHNCLYIIGGMINNRHVYSVSRVDLKTKK-WKTV--------------TNMSSLKSEVSTCVNDGKLYVIGGLEFSISTGIAEYLKTSKWLPNLITPRYSGASVFVNDDIYVMGGVYTTMRN.......................................... 175
5 -5.670IDP02804 hypothetical protein lmo2181 [Listeria monocytogenes EGD-e] lmo2181 [Listeria monocytogenes EGD-e]  ali follow..  9  32..............................................ENKHNQTILDDAKAVYTKDAATTNVNGEVRDELRDLQKLNKDMVGWLYPKDNDYYLHHNYKNFKDYRNTNEFLDKNTIIYGHNMKDGSMFADLRKYLDKDFLVAHPTFSYESGLTNYEEFPETTDFEDYLQKVKQSVYTSNVKVSGKDRIIT----STCDTEKDYEKGRMVI................................................... 239
6 -5.670IDP91521 C2 domain-containing protein [Toxoplasma gondii ME49] TGME49_040910 [Toxoplasma gondii ME49]  ali follow..  10 1841.....AAMERQQRLQKMVSGVKAAYRRLEEENTRLAATRRRDDKLQRQVEAERERAVELLKEATRRAKEEKDLIARQPPPARDWSDTVVLSTPQIFVNS--QAACAPFADSGRDEGGRDEWYEVSDACSRRAESS-------ESRTTAGAKLRQQQLDLAGRT.......................................................................................................... 1990
7 -5.310IDP01784 gene: ttrA; tetrathionate reductase complex subunit A [Salmonella typhimurium LT2] STM1383 [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]  ali follow..  11  65.....WQQNPQQTIAMTQCFGCWTQCGIRARVNADGK------VIRIAGNPYHPLSQEHPIDSSVPFSEAMEQLAGESGLDCARGATLLES-LY-SPLRLLEPMKRVGKR---------------------GEGKWQRI-SFEQLIEEVVEGGDLFGEGHVDGPSFGPKTFALNSFGAGSGALMGDKPDWENVEFAL---GTSASARLRENFQY-VVVA-LPLSTVLADPRGRWQPVMPGSDS.......................... 348
8 -5.060IDP05264 putative polysaccharide deacetylase [Clostridium difficile 630] CD3257 [Peptoclostridium difficile 630]  ali follow..  10  25..............TGTLLEEKINNVPVENISSKGENTLELLSQSNTLGEIIYKASQEETKGPGATSEKVAYITTNALLDILKENDVKATFFMLNQNMKNHKEEVRRVLEEENS----------IGFHSVSHEVTVGEFNTCNNTLQEITGQSSKLIRLPYGSKPYMPEGSYNKL----------MANDYLIWDWNLD-------TQDWKSSTSQIVSNILYYGRKRDELVVLIHEKEQSLNALNNIIRILKE................ 253
9 -5.020IDP05613 putative polysaccharide deacetylase [Bacillus anthracis str. Ames] BA_5436 [Bacillus anthracis str. Ames]  ali follow..  8  20...........................................SPHAGATTIPPAEHHPNTETTSSTKKIAYLTTTQILNILKEKNGKATFFVIGGKVPHYKKTMQRLIKDGHYIGLHSMSHDVKRLYTGDPSALITEMEQTQNIVQQVTELNTHLVRVPYGSMPYLKKNYRDAL----------VSAQYKMWDWTID------TYDWKSYDNPSAILERVRNQSDEQVEVILMHDSSVTVQILPQVIDYLQS................ 221
10 -4.990IDP04094 gene: astE; succinylglutamate desuccinylase [Yersinia pestis CO92] YPO1966 [Yersinia pestis CO92]  ali follow..  13  38................................................................................................................PHRSYTQSVVISAGIHG--NETAPIEILN-TDLLAGQLPLSVRLLVLLGNPPAIRKGKRY--------------SNDINR--FGGRYQHYTPSDETRRASTLEQRVMAFFQASHTS--ERLHYDLHTAIRG.......................... 152
FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Dunbrack RL Jr, Dunker K, Godzik A. Protein structure prediction in biology and medicine. Pac Symp Biocomput. 2000;(12):93-4.