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Query: gi|6319256|ref|NP_009339.1| NADP(+)-dependent glutamate dehydrogenase, synthesizes glutamate from ammonia and alpha-ketoglutarate; rate of alpha-ketoglutarate utilization differs from Gdh1p; expression regulated by nitrogen and carbon sources; Gdh3p (YAL062W) [Saccharomyces cerevisiae], from S.cerevisiae

Results of FFAS03 search in H.sapiens
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MTSEPEFQQAYDEIVSSVEDSKIFEKFPQYKKVLPIVSVPERIIQFRVTWENDNGEQEVAQGYRVQFNSAKGPYKGGLRFHPSVNLSILKFLGFEQIFKNALTGLDMGGGKGGLCVDLKGKSDNEIRRICYAFMRELSRHIGKDTDVPAGDIGVGGREIGYLFGAYRSYKNSWEGVLTGKGLNWGGSLIRPEATGFGLVYYTQAMIDYATNGKESFEGKRVTISGSGNVAQYAALKVIELGGIVVSLSDSKGCIISETGITSEQIHDIASAKIRFKSLEEIVDEYSTFSESKMKYVAGARPWTHVSNVDIALPCATQNEVSGDEAKALVASGVKFVAEGANMGSTPEAISVFETARSTATNAKDAVWFGPPKAANLGGVAVSGLEMAQNSQKVTWTAERVDQELKKIMINCFNDCIQAAQEYSTEKNTNTLPSLVKGANIASFVMVADAMLDQGDVFLast
1 -95.600sp|P49448|DHE4_HUMAN Glutamate dehydrogenase 2, mitochondrial OS=Homo sapiens GN=GLUD2 PE=1 SV=2  ali follow..  23  61.EDDPNFFKMVEGFFDRGASISEEQKRNRVRGILRIIKPCNHVLSLSFPIRRDDGSWEVIEGYRAQHSQHRTPCKGGIRYSTDVSVDEVKALASLMTYKCAVVDVPFGGAKAGVKINPKNYTENELEKITRRFTMELAKFIGPGVDVPAPDMNTGEREMSWIADTYASTIGHAHACVTGKPISQGGIHGRISATGRGVFHGIENFINEASYMTPGFRDKTFVVQGFGNVGLHSMRYLHRFGAKCIAVGESDGSIWNPDGIDPKELEDFKLQHGSILGFPK---------------AKPYEGSILEVDCDILIPAATEKQLTKSNAPRVKAKII---AEGANGPTTPEADKIFL---------ERNILVIPDLYLNAGGVTVSYFEWLKNLNHVSYGRLTFKYERDSNYHLLLSVQESLERKFGTAMKYNLGLDLRTAAYVNAIEKVFKVYSEAGVTF 557
2 -95.400sp|P00367|DHE3_HUMAN Glutamate dehydrogenase 1, mitochondrial OS=Homo sapiens GN=GLUD1 PE=1 SV=2  ali follow..  23  61.EDDPNFFKMVEGFFDRGASISEEQKRNRVRGILRIIKPCNHVLSLSFPIRRDDGSWEVIEGYRAQHSQHRTPCKGGIRYSTDVSVDEVKALASLMTYKCAVVDVPFGGAKAGVKINPKNYTDNELEKITRRFTMELAKFIGPGIDVPAPDMSTGEREMSWIADTYASTIGHAHACVTGKPISQGGIHGRISATGRGVFHGIENFINEASYMTPGFGDKTFVVQGFGNVGLHSMRYLHRFGAKCIAVGESDGSIWNPDGIDPKELEDFKLQHGSILGFP---------------KAKPYEGSILEADCDILIPAASEKQLTKSNAPRVKAKII---AEGANGPTTPEADKIFL---------ERNIMVIPDLYLNAGGVTVSYFEWLKNLNHVSYGRLTVHSGLAYTMERSARQIMRTAMKYNL------GLDLRTAAYVNAIEKVFKVYNEAGVTF 557
3 -8.250sp|Q16798|MAON_HUMAN NADP-dependent malic enzyme, mitochondrial OS=Homo sapiens GN=ME3 PE=2 SV=2  ali   14  5.............................PRGLFITIHDKGHLATMLNSWPEDNIKAVVVTGERILGLGDLGCYGMGI---PVGKLALYTACGGVNPQQCLPVLLDVGTNNEELLRDPQRVHGKAYDDLLDEFMQAVTDKFGINCLIQFEDFANAN-----LLNKYRNKYCMFNDDIQGT-----------------ASVAVAGILAALRITKNKLSNHVFVFQGAGEAAMGIAHLLKAEATRKIWMVDSKGLIVKGRSHLNHEKEMFAQDHPEVNSLEEVVRLVK--------------------PTAIIGVAAIAGAFTEQILRDMASFHERPIIFALSNPTS................................................................................................................ 296
4 -7.590sp|P48163|MAOX_HUMAN NADP-dependent malic enzyme OS=Homo sapiens GN=ME1 PE=1 SV=1  ali follow..  14  120.............................PRGLFITIHDRGHIASVLNAWPEDVIKAIVVTGERILGLGDLGCNGMGI---PVGKLALYTACGGMNPQECLPVILDVGTENEELLKDPRRVRGSEYDDFLDEFMEAVSSKYGMNCLIQFEDFANVN-----LLNKYRNQYCTFNDDIQGT-----------------ASVAVAGLLAALRITKNKLSDQTILFQGAGEAALGIAHLIVMALEK-IWLVDSKGLIVKGRASLTQEKEKFAHEHEEMKNLEAIVQEIK--------------------PTALIGVAAIGGAFSEQILKDMAAFNERPIIFALSNPTSPFDPVTLPNGQTLYPGQGNNSYVFPGVAL---GVVACGLRQITD----------------NIFLTTAEVIAQQVSDKHLEEGRPPLNTIRDVSLKIAE-KIVKDAYQEKT.. 526
5 -7.420sp|Q13423|NNTM_HUMAN NAD(P) transhydrogenase, mitochondrial OS=Homo sapiens GN=NNT PE=1 SV=3  ali   10  46..............................................................................................................................................................................................ANIAGYKAVVLAANHFGRQITAAGKVPPAKILIVGGGVAGLASAGAAKSMGAIVRGFDTRAAALEQFKSLGAEPLEVDLKESGEGQGGYAKEMSKEFIEAEMKLFAQ------QCKEVDILISTAL---------------------------IPGKKAPVLFNKEMIESMKEGSVVV--DLAAEAGGNFETTKPLYIHKGITHIGYTDLPSRMATQASTLYSNNITKLLKAISPDKDNFYFDVKDDFDFGTMGHVIRVVMKDGKV. 284
6 -7.000sp|P23368|MAOM_HUMAN NAD-dependent malic enzyme, mitochondrial OS=Homo sapiens GN=ME2 PE=1 SV=1  ali follow..  10  130.............................PKGLFISISDRGHVRSIVDNWPENHVKAVVVTGERILGLGDLGVYGMGI---PVGKLCLYTACAGIRPDRCLPVCIDVGTDNIALLKDPKRDRTQQYDDLIDEFMKAITDRYGRNTLIQFEDFGNHN-----FLRKYREKYCTFNDDIQGT-----------------AAVALAGLLAAQKVISKPISEHKILFLGAGEAALGIANLIVMSMVE-IWMFDKYGLLVKGRKAKIDSYQEPFTHSAPESIPDTFEDAVNILK-----------------PSTIIGVAGAGRLFTPDVIRAMASINERPVIFALSNPTSPFGPVKLTDGRVFTPGQGNNVYIFPGVAL---AVILCNTRHIS----------------DSVFLEAAKALTSQLTDEELAQGRPPLANIQEVSINIAI-KVTEYLYANKM.. 539
7 -6.210sp|Q16798|MAON_HUMAN NADP-dependent malic enzyme, mitochondrial OS=Homo sapiens GN=ME3 PE=2 SV=2  ali   10  2.............................................................................................................................................................................................NDDIQGTASV-AVAGILAALRITKNKLSNHVFVFQGAGEAAMGIAHLLVMALEK-IWMVDSKGLIVKGRSHLNHEKEMFAQDHPEVNSLEEVVRLVK--------------------PTAIIGVAAIAGAFTEQILRDMASFHERPIIFALSNPTSCTAEKCYRVTEGRGIFASNNAYVFPGVAGGIRHIPDEIFLLTAEQIAQEVSEQHLSQTIRDVSLRIAIKVLDYAYKHNLASYYPEPKDKEA..................... 273
8 -6.170sp|Q9UDR5|AASS_HUMAN Alpha-aminoadipic semialdehyde synthase, mitochondrial OS=Homo sapiens GN=AASS PE=1 SV=1  ali   63......................................................................................................................................................................................................................SIGPLTFVFTGTGNVSKGAQAIFNELPCEYVEPHELKEVSQTG---DLRKVYGTVLSRHHHLVRKTDAVYDPAEYDKHPERYISRFNTDIAPYTTCLINGIY----EQNTPRLLTRQDAQSLLAPGKFSPAGVEGCPALPHK---------LVAICDISADTGG-----IEFMTECTTIEHPFCMYDADQHIIHDSVEGSGILMCSIDNLPAQLPIEATECFGDMLYPY.............. 272
9 -6.150sp|O60774|FMO6_HUMAN(removed signalp:1-17) Putative dimethylaniline monooxygenase [N-oxide-forming] 6 OS=Homo sapiens GN=FMO6P PE=5 SV=1  ali follow..  10  21...........................................................................GGLKFSDHTEEGRASIYQSVFT-MMCFPDFPYPDD-------PNYIHHSKLQEYIKTYAQKLLRYIQFETLVSGIKKCPSFLVTGQWVVVTEKDGKQESTIFDAVMICSGVYPNLPTDSFPGLDQFRGNYLHSRDYKNPEFKGKRVLVIGLGNSGSDIAVELSRLATQVIISTRSASWVMSRDGYPWDMMYVTRFASFLRNVLPSFISDWLYVQKMNTWFKHEN-RKEPVFNDELPSRILCGTLSIKPSVKEFTETSAVF----EDGTMFEAIDSVIFATGYDYSYEKPTLAVI---LVQSLGAAIPTADLQAWWAAKVFANSCTLPTTNEMMDDTDEKMGKKLKCMFSSFFMFGQSQTLQTDYITYVDELGSFI....... 431
10 -5.990sp|A0AVT1|UBA6_HUMAN Ubiquitin-like modifier-activating enzyme 6 OS=Homo sapiens GN=UBA6 PE=1 SV=1  ali   2.........................................................................................................................................................EGSEPVAAHQGEEASCSSWGTGSTNKNLPIMSTASVEIDDALYS-----RQRYVLGDTAMQKMAKSHVFLSGMGGLGLEIAKNLVLAGIKAVTIHDTE--KCQAWDLGTNFFLS------------------EDDVVNKRNRAEAVLKHIAELNPYVHV-TSSSVPFNETTDLSFLDKYQCVVLTEMKLPLQKKINDFCR---------SQCPPIKFISADVHGIWSRLFCDFGDEFEVLDTTGEEPKEIFISNITQANPGIVTCLENHPHKLETGQFLTFREINGMTGLNGSIQQITVIS... 267

FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Li W, Wooley JC, Godzik A. Probing metagenomics by rapid cluster analysis of very large datasets. PLoS ONE. 2008;3(10):e3375. Epub 2008 Oct 10.