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Query: gi|6319279|ref|NP_009362.1| Pyruvate kinase, functions as a homotetramer in glycolysis to convert phosphoenolpyruvate to pyruvate, the input for aerobic (TCA cycle) or anaerobic (glucose fermentation) respiration; Cdc19p (YAL038W) [Saccharomyces cerevisiae], from S.cerevisiae

Results of FFAS03 search in H.sapiens
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MSRLERLTSLNVVAGSDLRRTSIIGTIGPKTNNPETLVALRKAGLNIVRMNFSHGSYEYHKSVIDNARKSEELYPGRPLAIALDTKGPEIRTGTTTNDVDYPIPPNHEMIFTTDDKYAKACDDKIMYVDYKNITKVISAGRIIYVDDGVLSFQVLEVVDDKTLKVKALNAGKICSHKGVNLPGTDVDLPALSEKDKEDLRFGVKNGVHMVFASFIRTANDVLTIREVLGEQGKDVKIIVKIENQQGVNNFDEILKVTDGVMVARGDLGIEIPAPEVLAVQKKLIAKSNLAGKPVICATQMLESMTYNPRPTRAEVSDVGNAILDGADCVMLSGETAKGNYPINAVTTMAETAVIAEQAIAYLPNYDDMRNCTPKPTSTTETVAASAVAAVFEQKAKAIIVLSTSGTTPRLVSKYRPNCPIILVTRCPRAARFSHLYRGVFPFVFEKEPVSDWTDDVEARINFGIEKAKEFGILKKGDTYVSIQGFKAGAGHSNTLQVSTVLast
1 -132.000sp|P14618|KPYM_HUMAN Pyruvate kinase isozymes M1/M2 OS=Homo sapiens GN=PKM2 PE=1 SV=4  ali follow..  50  25.TFLEHMCRLDIDSPPTARNTGIICTIGPASRSVETLKEMIKSGMNVARLNFSHGTHEYHAETIKNVRTATESFAYRPVAVALDTKGPEIRTGLIKGSAEVELKKGATLKITLDNAYMEKCDENILWLDYKNICKVVEVGSKIYVDDGLISLQVKQK-GADFLVTEVENGGSLGSKKGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMVFASFIRKASDVHEVRKVLGEKGKNIKIISKIENHEGVRRFDEILEASDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNRAGKPVICATQMLESMIKKPRPTRAEGSDVANAVLDGADCIMLSGETAKGDYPLEAVRMQHLIAREAEAAIYHLQLFEELRRLAPITSDPTEATAVGAVEASFKCCSGAIIVLTKSGRSAHQVARYRPRAPIIAVTRNPQTARQAHLYRGIFPVLCKDPVQEAWAEDVDLRVNFAMNVGKARGFFKKGDVVIVLTGWRPGSGFTNTMRVVPV 530
2 -126.000sp|P30613|KPYR_HUMAN Pyruvate kinase isozymes R/L OS=Homo sapiens GN=PKLR PE=1 SV=2  ali follow..  49  68.TFLEHLCLLDIDSEPAARSTSIIATIGPASRSVERLKEMIKAGMNIARLNFSHGSHEYHAESIANVREAVESFSYRPVAIALDTKGPEIRTGILQGGSEVELVKGSQVLVTVDPAFRTRGNANTVWVDYPNIVRVVPVGGRIYIDDGLISLVVQKI-GPEGLVTQVENGGVLGSRKGVNLPGAQVDLPGLSEQDVRDLRFGVEHGVDIVFASFVRKASDVAAVRAALGPEGHGIKIISKIENHEGVKRFDEILEVSDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNLAGKPVVCATQMLESMITKPRPTRAETSDVANAVLDGADCIMLSGETAKGNFPVEAVKMQHAIAREAEAAVYHRQLFEELRRAAPLSRDPTEVTAIGAVEAAFKCCAAAIIVLTTTGRSAQLLSRYRPRAAVIAVTRSAQAARQVHLCRGVFPLLYREPPEAIWADDVDRRVQFGIESGKLRGFLRVGDLVIVVTGWRPGSGYTNIMRVLSI 573
3 -7.470sp|Q8N0X4|CLYBL_HUMAN(removed signalp:1-26) Citrate lyase subunit beta-like protein, mitochondrial OS=Homo sapiens GN=CLYBL PE=2 SV=2  ali follow..  13  33....................................................................................................................................IKKIPSLNVDCAVLDCEDGVAANKKNEARLRIVKTLEDIDLGPTE------KCVRVNSVSGLAEEDLETLLQSRPSSLMLPKVESPEEIQWFADKFSFHEQPMNLIPFVETAMGLLNFKAVCEETDAVVFGGEDFRASIGATDILYARQKIVVIAKAFG---LQAIDLVYIDFRDGAGLLRQSREGAAMGFTGKQVI----------HPNQ-IAVVQEQFSPSPEKIKWAEELIAAFKEHQQLGKGAFTFQGSMIDMPLLKQAQNTVTLATS................................................................................................ 310
4 -7.230sp|Q8IWV2|CNTN4_HUMAN Contactin-4 OS=Homo sapiens GN=CNTN4 PE=1 SV=1  ali   11  2............................................................................................GKNVARGQLTFYAQPNWIQKINDIHVAMEENVFWTYKWLKNGEPLLTRDRIQIEQGTLNITIVNLSDAGMYQCLAENKGVIFSNAELSVIAVGPDFSRTLLKRVTLVKVGGEVVIECKPYTWKKGRDILKENERITISEDGNLRIINVTKSDAGATNHFGTASSTGNLVVKDPTRVMVPPSSMDVTVGESIVLPCQVTHDHSIVFTWSFNGHLIDFDRDGDHFERVGGQDSAGDLMIRNIQLKHAGKYVCMVQTSVDRLSAAADLIV............................................................................................................................................. 293
5 -6.920sp|Q9UQ52|CNTN6_HUMAN(removed signalp:1-19) Contactin-6 OS=Homo sapiens GN=CNTN6 PE=1 SV=1  ali   12  2..............................................................................................EQKIQNTHLSIYDNLLWECKAS-----GKPNPWYTWLKNGERLNPEERIQIENGTLIITMLNVSDSGVYQCAAENKQIIYANAELRVLASAPDFSKSPVKKKSFVQVGGDIVIGCKPISWKRGTETLRQSKRIFLLEDGSLKIYNITRSDAGATNQFGTAKNTGSLIVKERTVITVPPSKMDVTVGESIVLPCQVSHDPSIEVVDVIDLKKGVAHFERIGGESVGDLMIRNIQ------LHHSGKYLCTVQTTLESLSAVADIIV............................................................................................................................................. 275
6 -6.700sp|Q9P232|CNTN3_HUMAN(removed signalp:1-19) Contactin-3 OS=Homo sapiens GN=CNTN3 PE=1 SV=3  ali   12  2..............................................................................................VQLIKDVEIAVEDSLYWEC-----RASGKPKPSYRWLKNGAALVLEERTQIENGALTISNLSVTDSGMFQCIAENKGLVYSSAELKVVASAPDFSKNPMKKLVQVQVGSLVSLDCKPSSWKKGDVSVQEHERISLLNDGGLKIANVTKADAGAENQFGKANGTTHLVVTEPTRITLAPSNMDVSVGESVILPCQVQHDPLLDIIALADFKKDGSHFEKVGGSSSGDLMIRNIQ------LKHSGKYVCMVQTGVDSVSSAADLIV............................................................................................................................................. 275
7 -6.450sp|Q02246|CNTN2_HUMAN(removed signalp:1-30) Contactin-2 OS=Homo sapiens GN=CNTN2 PE=1 SV=1  ali   12  4..................................................................................................SDTEADIGSNLRWGCAAA-----GKPRPTVRWLRNGEPLASQNRVEVLAGDLRFSKLSLEDSGMYQCVAENKGTIYASAELAVQALAPDFRLNPVRRLIPAARGGEILIPCQPVLWSKGTEILVNSSRVTVTPDGTL-IIRNISRSDEAENFMGKANSTGILSVRDATKITLAPSSADINLGDNLTLQCHASHDPTLTFTWTLDDFPIDFDKPGGHYRRTNVKETIGDLTILNAQLRHGGKYTCMAQTVVDSASKEAT................................................................................................................................................ 271
8 -6.360sp|Q9UPX0|TUTLB_HUMAN(removed signalp:1-20) Protein turtle homolog B OS=Homo sapiens GN=IGSF9B PE=2 SV=2  ali   9  4.......................................................................................HGL----REEPEFVTARAGESVVLRCDVIHPVTGQPPPYVVEWFKFGVPIPIGRASLHDKASLRLEQVRSEDQGWYECKVLMQQYDTFHNGSWVHLTINAPPTFTETPPQYIEAKEGGSITM-IVTWLKEGTLLGASGKYQVSDGS---TVTSVSREDRAYSIQGEAVHTTHLLVQGPPFIVSPPENITVNISQDALLTCRAEAYPGNLTYTWYWQ--DENVYFQNDLKLRVRILIDGTLIIFRVKPEDSGKYTCVPSNSLGRSPSAS................................................................................................................................................. 296
9 -6.360sp|Q9HCK4|ROBO2_HUMAN(removed signalp:1-21) Roundabout homolog 2 OS=Homo sapiens GN=ROBO2 PE=1 SV=2  ali   10  7...........................................................................................................................................EERISIRGGKLMISNTRKSDAGMYTCVGTNMVGERDSDPAELPTFLRRPINQVVLEEEAVEFRCQQGDPQPTVRWKKDDADLPRGRYDIKDDYT---RIKKTMSTDEAENRVGKMEASATLTVRAPPQFVVRPRDQIVAQGRTVTFPCETKGNPQPAVFWQKEGSQNLLFPNQPQQPNSRCSVSPTGDLTITNIQRSAGYYICQALTVAGSILAKAQLEV-----------TDVLTDRPPPIILQGPANQTLAVDGTALLKCKATGDPLPVISWLKEGFTFPGRDPRATIQEQ.................................................................... 299
10 -6.330sp|P19113|DCHS_HUMAN Histidine decarboxylase OS=Homo sapiens GN=HDC PE=2 SV=2  ali   16  1............................................................................................................................................................................FNPSKWMMVH---FDCTGFWVKDKYKLQQTFSVNPIYLRHANSGVATDFMHWQIPLSRRFRSVKLWFVI-RSFGVKNLQAHVRHGTEMIPAKRHLGL-FRLKGPNCLTENVLKEIAKAGRLFLIPATIIRFTVTSQFTTRDDILRDWNLIRDAATLILSQHCTS.................................................................................................................................................................... 181
FFAS is supported by the NIH grant R01-GM087218-01
1 4 8 3 1 9   jobs submitted since Jan 1, 2011
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Ye Y, Godzik A. Multiple flexible structure alignment using partial order graphs. Bioinformatics. 2005 Mar 3;