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Query: gi|6319258|ref|NP_009341.1| NAD-dependent (R,R)-butanediol dehydrogenase, catalyzes oxidation of (R,R)-2,3-butanediol to (3R)-acetoin, oxidation of meso-butanediol to (3S)-acetoin, and reduction of acetoin; enhances use of 2,3-butanediol as an aerobic carbon source; Bdh1p (YAL060W) [Saccharomyces cerevisiae], from S.cerevisiae

Results of FFAS03 search in HGM_OVER
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MRALAYFKKGDIHFTNDIPRPEIQTDDEVIIDVSWCGICGSDLHEYLDGPIFMPKDGECHKLSNAALPLAMGHEMSGIVSKVGPKVTKVKVGDHVVVDAASSCADLHCWPHSKFYNSKPCDACQRGSENLCTHAGFVGLGVISGGFAEQVVVSQHHIIPVPKEIPLDVAALVEPLSVTWHAVKISGFKKGSSALVLGAGPIGLCTILVLKGMGASKIVVSEIAERRIEMAKKLGVEVFNPSKHGHKSIEILRGLTKSHDGFDYSYDCSGIQVTFETSLKALTFKGTATNIAVWGPKPVPFQPMDVTLQEKVMTGSIGYVVEAFEEVVRAIHNGDIAMEDCKQLITGKQRIEDGWEKGFQELMDHKESNVKILLTPNNHGEMKLast
1 -5.120HGC00991 gi|163600283|dbj|BABF01000984.1|3.0 TMP01348;  ali follow..  1...........MQVDTKLINLKLWGYITMKKMIAYCGLCEK---------DAYIATINDNQELRKKTAKLWAELNNAPILPEHINCQGCRVDGIKTVFCDNMCGIRQCALEKGV---ATCGDCLD--LERCPTVGEI..................................................................................................................................................................................................................................................... 114
2 -3.290HGC00522 gi|163636101|dbj|BABG01000172.1|3.0 TMP00580;  ali follow..  1.................................................................................................................................................LQTNYKRQRMNIFDIAKQNQEKAWQVIKNTNII---------DAGAKINLVGSLRTGLLMKH-----------------------RDIDFHIYSSPLNLTDSFQAMARLAENPSIKRIECLLHTAEACIEWHAWYQNEENELWQMDMIHIREGSRYDGYFEKVAQRISEIMT---DEIRETILRLKYETPETEKIIGVEYYQAVIRDGVRDYSGFKEWRKQHPVTGVVE........ 200
3 -2.890PB015954 Q6WBB3_BIFBR/1-225 PB015954; Pfam-B_15954;  ali follow..  1..........................................................................................................................................................................METSSIELWHGIKHPEYGMGKPNNDYGRGFYCTRSIELAKEWACAGLDDGFANRYTLTTDGLTFLDLSQPPYTILNWLALLVENRRFQPTTAVAAQGIPDISQADVIVGYRADDSYFSFARTFVNNAISLDQLADAMRLGELGKQIVLISSRAFAALQFQDCEIARASTYHVLRNERDVTAREAYRRKSAEADIDGLFMRDIIREKTNDDPR 225
4 -2.840PB033130 gi|160880323|ref|YP_001559291.1| transglutaminase domain protein [Clostridium phytofermentans ISDg]gi|160428989|gb|ABX42552.1| transglutaminase domain protein [Clostridium phytofermentans ISDg]  ali follow..  10  2...........................................................................................................................................................................VCGAKVSLEILNYAEFASGCVSITIGLGDI-HIRAVKDGFFAEAMGHVRTQEEITLILNDNLLSKDWVTDSWEMCEVEAPKDSVKYQFNLTREQQATNRSKLREAK-------------LLRENRIESYYDEALAENVPDAKEILHLAKGNFMEIYRFLTVDGNNVDSNQDRLLKTLKVKDYKDVTASVLEDHLKVRES............ 197
5 -2.720PB007843 JCVI_PEP_1096682172521 /source_dna_id=JCVI_ORF_1096682172520 /offset=0 /translation_table=11 /length=152 /full_length=152  ali follow..  13  4.................................................................................................................................................................................................IISISGRPGLFEVHTQTRTG---VVATSLVDGKRINASLLSEINIYGLEKEVPLQEVLTMIHTKEEGKQCSVKPKSPADELEA----------------------------------------------FFDVFQDYDEERVYPSDIKKIIQWYNILAEKVPQVFKAETAEEESQEEVAVKEETSSD.. 148
6 -2.270PB010473 Q8A4J5_BACTN/121-234 PB010473; Pfam-B_10473;  ali follow..  12  2.........................................................................................................................................................................AFLLPLEAMEYEINKGAGNPSQYLFIFAGGLVALLVVVILYIAGVNQWICIPFG---FRLNARYGEHGLMKLLSGKRHPRYLI.................................................................................................................................. 100
7 -2.210PB155142 _HOMD.0127537_ bfor_c_1_1790 Tannerella forsythia ATCC 43037 [677748 - 680894] ORF  ali follow..  15  14................................................................................................................................................................PEDIE-SQTILKDAAATALYGSRGAN---GVVLITTKSGRRGKTHIAFTAEYGTSDFATPHALD.............................................................................................................................................................. 73
8 -2.170HGC00711 gi|162743779|dbj|BAAZ01020484.1|1.0 TMP00907;  ali follow..  21  31....................................................................................................................................................................................................GAGTVGVIAVLLAAALGVSGLIQAQAAAGRSRAAADLGATALSSIVAPGDPCEAASRVARANGAEVTTCSVTGEDVVVEVSVEA...................................................................................................... 121
9 -1.900HGC00164 gi|163636082|dbj|BABG01000191.1|4.0 TMP00833;  ali follow..  74...............................................................................................................................................................FADSLPDTFGNQIINEWFASKGLSGEEITPLDRLCYVGKRGMGALEFEPSSPINGMNESSVLHIEELTELAKSVFTDRMAFQVQLRQEGRNILDILKVGT........................................................................................................................... 173
10 -1.690PB003645 Q65HI2_BACLD/1-230 PB003645; Pfam-B_3645;  ali follow..  106...........................................................................................................................................................................................................LKDILETIIGVEDVSIVVNVDATSLKIFEKNRKTQETSTNETDKQGGKRTVSEMSSDEEIVIKNGDKETPVVVQTKKPDIRGVLVVAQGVDNVQIKKTIIEAVTRVLDV...................................................................... 215

FFAS is supported by the NIH grant R01-GM087218-01
1 3 7 7 9 2   jobs submitted since Jan 1, 2011
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Sikora S, Godzik A. Combination of multiple alignment analysis and surface mapping paves a way for a detailed pathway reconstruction--the case of VHL (von Hippel-Lindau) protein and angiogenesis regulatory pathway. Protein Sci. 2004 Mar;13(3):786-96. Epub 2004 Feb 06.