current user: public
If you have questions about the server, please let us know.

Query: gi|6319279|ref|NP_009362.1| Pyruvate kinase, functions as a homotetramer in glycolysis to convert phosphoenolpyruvate to pyruvate, the input for aerobic (TCA cycle) or anaerobic (glucose fermentation) respiration; Cdc19p (YAL038W) [Saccharomyces cerevisiae], from S.cerevisiae

Results of FFAS03 search in HGM_OVER
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
    .   10    .   20    .   30    .   40    .   50    .   60    .   70    .   80    .   90    .  100    .  110    .  120    .  130    .  140    .  150    .  160    .  170    .  180    .  190    .  200    .  210    .  220    .  230    .  240    .  250    .  260    .  270    .  280    .  290    .  300    .  310    .  320    .  330    .  340    .  350    .  360    .  370    .  380    .  390    .  400    .  410    .  420    .  430    .  440    .  450    .  460    .  470    .  480    .  490    .  500
# Score Template Links and tools%idFirst MSRLERLTSLNVVAGSDLRRTSIIGTIGPKTNNPETLVALRKAGLNIVRMNFSHGSYEYHKSVIDNARKSEELYPGRPLAIALDTKGPEIRTGTTTNDVDYPIPPNHEMIFTTDDKYAKACDDKIMYVDYKNITKVISAGRIIYVDDGVLSFQVLEVVDDKTLKVKALNAGKICSHKGVNLPGTDVDLPALSEKDKEDLRFGVKNGVHMVFASFIRTANDVLTIREVLGEQGKDVKIIVKIENQQGVNNFDEILKVTDGVMVARGDLGIEIPAPEVLAVQKKLIAKSNLAGKPVICATQMLESMTYNPRPTRAEVSDVGNAILDGADCVMLSGETAKGNYPINAVTTMAETAVIAEQAIAYLPNYDDMRNCTPKPTSTTETVAASAVAAVFEQKAKAIIVLSTSGTTPRLVSKYRPNCPIILVTRCPRAARFSHLYRGVFPFVFEKEPVSDWTDDVEARINFGIEKAKEFGILKKGDTYVSIQGFKAGAGHSNTLQVSTVLast
1 -3.050HGC00522 gi|163636101|dbj|BABG01000172.1|3.0 TMP00580;  ali follow..  10  1.................................................................................................................................................................................................................LQTNYKRQRMNIFDIAKQNQEKAWQ--VIKNTNIIQIWEDAGAKINLVGGLLMKHRDIDFHIYSSPLNLTD----------------SFQAMARLAENPSIKRIECANLLHTAEACMDMIHIREGSRYDGYFEKVAQRISEIMTDEIRETILRLKYETPETEKIIGVEYYQAVIRDGVRDYSGF........................................................................................................... 186
2 -2.460PB031792 gi|154174791|ref|YP_001409041.1| flavodoxin family protein [Campylobacter curvus 525.92]gi|112804021|gb|EAU01365.1| flavodoxin family protein [Campylobacter curvus 525.92]  ali follow..  11  2.....................................................................................................................................................................................................................YIDKGGPEAHFKRYIKEKGKKTGLFITLGADPAGEHGESMLKVGRELLNEGGN---------------EILAEFICQGAIDPKVIEEMKEMAAKMHPDENDLKNARKAF.................................................................................................................................................................................. 118
3 -1.900PB001934 Q6PSL5_CHLRE/821-1150 PB001934; Pfam-B_1934;  ali follow..  13  64..............................................................................MVIPMDAETPGGRL-EAIRHWATVLSVRLDLDAARGKLGPEACEMERQRFDGVIAMMERNDGPTLVVTDSQAIDVVHPWTLDRSAMAYQQNGGRLDP-EGLE------ALETLQDGDRVLISEACNHNRITSACNDIGMVQIPNKLEAALGGKKLQIEHAFGREFPELESG--KLAIHCGGCMIDAQKMGVPVTNYGVFFSWAAWPDALRRALEPWGVEPPVGTPATPAAAPATAASG........................................................................................................................................................................................ 330
4 -1.820PB044863 Q5LB69_BACFN/1-105 PB044863; Pfam-B_44863;  ali follow..  19  8......................................................................................................................................................................................................................................................................PSGTRSMEISEENLVTIEKYSLFQ-HLIDSNGIVDEAVLEKLKLNIRSLIASQEEDSKDLLD-IDVIYHNNMKAFGLQQLIKL........................................................................................................................................................... 90
5 -1.740PB202086 Q8G498_BIFLO/2-200 PB202086; Pfam-B_202086;  ali follow..  14  97.................................................................................................................................................................................................................VKAEQVKDSKTVESLGKELKASAPEYEGCVAENAQGLDAAAVKLNEQADWYETHEKSLSKAVRAVVESKAAKRLDDAKTNLTAKLDEASKLLAD-------SDGKVADNA..................................................................................................................................................................................... 199
6 -1.730PB050904 Q64SA2_BACFR/1-230 PB050904; Pfam-B_50904;  ali follow..  10  50.......................................................................................................................................................................................................................KQIKGQTQTALLQNSIATEFNQIHKWEKQSYLKTASGYASSLKACT------HLYNDGVRIFLTLGKLGKAIQNNPQGIVASMNMNNLYIETATELVSVFTLLNDAVAKGSNENMLTGA--------ERSKTLWALNDQLSD............................................................................................................................................... 179
7 -1.640HGC00024 gi|162813637|dbj|BABA01031072.1|2.0 TMP01508;  ali follow..  9  117....................................................................................................................................................................................................................................................TQIAKYNTFLENITDCPMEE-SKKEQWSAEVKCLRAYFFLNLAFYYTDPMPLKTLSVDEANSISQTPQTEV-----------SQVEKDLKTAIDLLPVHYLRGIWRLPGGG................................................................................................................................................. 217
8 -1.540PB019388 gi|83589066|ref|YP_429075.1| Radical SAM [Moorella thermoacetica ATCC 39073]gi|83571980|gb|ABC18532.1| Radical SAM [Moorella thermoacetica ATCC 39073]  ali follow..  8  1................................................................................................................................................................................................RADEFGYLFLDRPPYQVLASSAI-TYEEMLRLHAIYGNSHLADHAFAYLAATAFDGSYFAIYEALAAWWEARGLLRRGHSQRDLFNHLASFAIHLARGIATRVTVPPLPGYHDSILEINSHGDTPASGAEHSGCARNLTPAQLDR-KFDCLCRDRSRNFPGWMPPSPLTEEERSNWMARITTPRSMEKYMPGLVKESPANLRRHGFI..................................................................................................... 216
9 -1.530PB177066 Q891G9_CLOTE/1-159 PB177066; Pfam-B_177066;  ali follow..  10  13..............................................................................................................................................................................................MNDTQKNDLFYVCCL-IEFIGRKTKNRRSII--VQKLGKKELIRQLDIAEANHCLSFEQVSD--EIIEYFNIQEGDFHVESCKYNVPVYHRLIISIISEQDNLVDVLFEVFNSFISD------EISDFNSSVY................................................................................................................................................................................. 142
10 -1.510PB012771 _Gut.Meta.Jp.0094636_ gi|162817068|dbj|BABA01027641.1||1 (+ 249:636~0 complete)  ali follow..  11  1..........................................................................................................................................................................................................................................MKTTTTNELPAEIMENGIHYTLVGDYYFPTCMLGDKSPNGKWASLYERYLQEKHPHEYVRLIWADELAALLES---VQRECEEREAVLVREMAEAEGVNEEMKGNEQMAWVQRMEMICGRVEEVV............................................................................................................................................. 122
FFAS is supported by the NIH grant R01-GM087218-01
1 4 8 3 1 6   jobs submitted since Jan 1, 2011
Comments and questions to: webmaster
Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Dunbrack RL Jr, Dunker K, Godzik A. Protein structure prediction in biology and medicine. Pac Symp Biocomput. 2000;(12):93-4.