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Query: gi|6319260|ref|NP_009343.1|(removed signalp:1-19) Calnexin; integral membrane ER chaperone involved in folding and quality control of glycoproteins; chaperone activity is inhibited by Mpd1p, with which Cne1p interacts; 24% identical to mammalian calnexin; Ca+ binding not yet shown in yeast; Cne1p (YAL058W) [Saccharomyces cerevisiae], from S.cerevisiae

Results of FFAS03 search in NEW_HUMAN_DOMAINS
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst TSLLSNVTLAEDSFWEHFQAYTNTKHLNQEWITSEAVNNEGSKIYGAQWRLSQGRLQGSAWDKGIAVRTGNAAAMIGHLLETPINVSETDTLVVQYEIKLDNSLTCGGAFIKLMSGFMNVEALKHYAPDTEGVELVFGPDYCAPEINGVQFAINKVDKITHESKLRYLQEMPLSKLTDTSQSHLYTLIIDESAQSFQILIDGKTVMVREHIEDKKKVNFEPPITPPLMIPDVSVAKPHDWDDRIRIPDPEAVKLSDRDERDPLMIPHPDGTEPPEWNSSIPEYILDPNAQKPSWWKELEHGEWIPPMIKNPLCTAERGCGQQIPGLINNAKYKGPGELNEIINPNYMGEWHPPEIENPLYYEEQHPLRIENVISGVILEFWSGSPNMLISNIYVGKNVTEAQIIGNKTWLMRDRAFRGSDGPTERKFMNSRLGNLQTTFHNERESPNPFDRIIDRILEQPLKFVLTAAVVLLTTSVLCCVVFTLast
1 -5.670sp|Q99932|SPAG8_HUMAN Sperm-associated antigen 8 OS=Homo sapiens GN=SPAG8 PE=1 SV=2  ali   15  12...............................................................................................................................................................................................................................................................................................................IPPGFRNLVADRVPNYTSWSQHCPWEPQKQPPWEFLQVLEPGARGLWKPPDIK-----GKLMVCYETLPRGQCLLYNWEEERAT-LDQVPSMQDGSESFFFRH............................................................................. 110
2 -5.420sp|P00533|EGFR_HUMAN Epidermal growth factor receptor OS=Homo sapiens GN=EGFR PE=1 SV=2  ali   15  3............................................................................................................................................................................................................................................................................TAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGS---HQISLDNPDYQQDKPNGIFKGSTAENAEYLR..................................................................................................................................................... 71
3 -5.260sp|Q12836|ZP4_HUMAN Zona pellucida sperm-binding protein 4 OS=Homo sapiens GN=ZP4 PE=2 SV=1  ali   10....................................................................................................SSVLHCGPWSFQFANQEATSPPVLIAWDNQGLLHELQNDSDCGTWIRK-SVVLE---------------------------ATYSSCYVTEWDSHYIMPVGVEGAGAAEHKVVTERKLLKCPMDLLA................................................................................................................................................................................................................................................................ 115
4 -5.260sp|P60852|ZP1_HUMAN Zona pellucida sperm-binding protein 1 OS=Homo sapiens GN=ZP1 PE=2 SV=1  ali   13  7..................................................................................................GLRHSYDCGIKGMQLVFPRPGQTLRFKVVDEFGNRFDVNNCSICYHWVTSAVFSADYRG-----------------------------CHVLEKDGRFHLRVFMEAVLPNGRVDVAQDATLICPKPDPSRTLDSQLAPPA..................................................................................................................................................................................................................................................... 123
5 -5.030sp|Q9H1A4|APC1_HUMAN Anaphase-promoting complex subunit 1 OS=Homo sapiens GN=ANAPC1 PE=1 SV=1  ali   5..........................................................................PNASVTGPHNLETCLSVVLLSLAM-----VMAGSGVLQLCRFLHMKTGGEMNYGFHLAHHMALGLLFLGGGRYSLSTSNSSIAALLCALYPHFPAHSTDNRYHLQALRHLYVLAAEP---RLLVPVDVDTNTPCYALLEVTYKGTQWYEQTKEELMAPTLLPELHLLKQIKVKGPRYWELLIDLSKGTQHLKSILSKDGVLYVKLRASYKEDPMG.................................................................................................................................................................................................. 217
6 -5.000sp|O60393|NOBOX_HUMAN Homeobox protein NOBOX OS=Homo sapiens GN=NOBOX PE=1 SV=4  ali   11  13.......................................................................................................................................................................................................................................................................................EDSLFMFPCGPSGGTSQGYCPGASSGQILMQPPA-GNIGTASWSDPCLPELPFPGPFCPQALGHPPGGDGYFPDLFPTP............................................................................................................................. 90
7 -4.980sp|Q96CC6|RHDF1_HUMAN Inactive rhomboid protein 1 OS=Homo sapiens GN=RHBDF1 PE=1 SV=2  ali   2...........................................RPYGLGMVGRLTNRTYRKRIDSFVKRQIEDMDDHRPF--TYWLTFVHSLVTILAVCIYGIAPVGFSQHETVDSVLRNRGVYENVKYVQQENFWIGP----SSEALIHLCMRQDPQVHSFIRSAREREKHSACCVRNDRSGCVQTSEEECSSTLAVWVKWPIHPSAPELAGHKRQFGSVCHQDPRVCDEPSSEDPHEWPE-DITKWPICTKNSAGNHTNHPHMDCVITGRP----------TKGRCEITSREYCDFMRGYFEATLCSQVHCMDDV-CG................................................................................................................................................................... 273
8 -4.860tr|F5H5C0|F5H5C0_HUMAN Uncharacterized protein OS=Homo sapiens GN=PEX5 PE=4 SV=1  ali   13  2..........................................................................................................................................................................................................QTFKMDDLLAEMQQIEQSNFRQAPQRAPGADLALSENWAQEDAVDVTQDYNETDWSQEFISEVTDPLSVSPARWAEEEKLWLGEPEGTATDRWYDEYHPE..................................................................................................................................................................................... 113
9 -4.820sp|A0PJX8|TMM82_HUMAN Transmembrane protein 82 OS=Homo sapiens GN=TMEM82 PE=2 SV=2  ali   13  1................................................................LEFSLRAVSTLLSLGKGSQGAAERLQLYLLQYSL----GLTCGLSFLQ-LATLLGLGARRLHRHVCRLYELHSSQRYCGV-GRALAIAFAVGDLAAVALINQDFLTTSEAMRFWTPLTICYTLLVQRQHPGLQSQVQTVLVRMGGLF................................................................................................................................................................................................................................................................................ 180
10 -4.550sp|Q5SQN1|SNP47_HUMAN Synaptosomal-associated protein 47 OS=Homo sapiens GN=SNAP47 PE=2 SV=3  ali   1.........................................................................................DVCIHTWPCTYYLEPK-GQLSL-------------------TSLSLRFMTDSTG----EILVSFPLSSIVEIKKEASHFIFSSITILEKGHAKHWFSSLRPSRNVVFSII............................................................................................................................................................................................................................................................................................ 91

FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Ye Y, Godzik A. Comparative analysis of protein domain organization. Genome Res. 2004 Mar;14(3):343-53.