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Query: gi|6319256|ref|NP_009339.1| NADP(+)-dependent glutamate dehydrogenase, synthesizes glutamate from ammonia and alpha-ketoglutarate; rate of alpha-ketoglutarate utilization differs from Gdh1p; expression regulated by nitrogen and carbon sources; Gdh3p (YAL062W) [Saccharomyces cerevisiae], from S.cerevisiae

Results of FFAS03 search in PfamA32U
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MTSEPEFQQAYDEIVSSVEDSKIFEKFPQYKKVLPIVSVPERIIQFRVTWENDNGEQEVAQGYRVQFNSAKGPYKGGLRFHPSVNLSILKFLGFEQIFKNALTGLDMGGGKGGLCVDLKGKSDNEIRRICYAFMRELSRHIGKDTDVPAGDIGVGGREIGYLFGAYRSYKNSWEGVLTGKGLNWGGSLIRPEATGFGLVYYTQAMIDYATNGKESFEGKRVTISGSGNVAQYAALKVIELGGIVVSLSDSKGCIISETGITSEQIHDIASAKIRFKSLEEIVDEYSTFSESKMKYVAGARPWTHVSNVDIALPCATQNEVSGDEAKALVASGVKFVAEGANMGSTPEAISVFETARSTATNAKDAVWFGPPKAANLGGVAVSGLEMAQNSQKVTWTAERVDQELKKIMINCFNDCIQAAQEYSTEKNTNTLPSLVKGANIASFVMVADAMLDQGDVFLast
1 -73.700PF02812.18; R6WCN3_9CLOT/34-162; Glu/Leu/Phe/Val dehydrogenase, dimerisation domain  ali follow..  31  1.......................................PERELKVALPVRMDDGSLKVFEGFRIQHSTLRGPAKGGVRYHQNVNVDEVRALSAWMTFKCAVAAIPYGGGKGGIVCRPREMSKGELERLTRTYIDKISAIISPNTDIPAPDVGTNAQTMDWMVDEYSK................................................................................................................................................................................................................................................................................................. 129
2 -72.400PF00208.21; DHE3_ORYSJ/176-408; Glutamate/Leucine/Phenylalanine/Valine dehydrogenase  ali follow..  32  1........................................................................................................................................................................................GGSLGRDAATGRGVMYATEALLTEY---SESISGSTFVIQGLGNVGSWAAKLIHQKGGKIVAVGDVTGAIRNKSGIDIPALLKHRSEGGSLEDFYG--------------AEVMDAAELLVHECDVLVPCALGGVLNRENAAEVKARFI---IEGANHPTDTEADEILA---------KKGVIVLPDIYANSGGVVVSYFEWVQNIQGFMWDEEKVNRELQKYMKNAFQNIKDMCKSQN--------CNLRMGAFTLGVNRVAKATLLRG... 233
3 -22.600PF05088.12; A4XWG7_PSEMY/77-1608; Bacterial NAD-glutamate dehydrogenase  ali follow..  13  640..TAEDLEDKQQKLEQAILAALDNVAVLNEDRILRRYLD-KATLRTNFFQADASGAAKSYFSFKLSHLRFGDVARGGLRWSDREERTEVLGLVKAQQVKNAV--IVPMGAKGGFVPRKRDEVMAEGIACYRIFISGLLDITDNLKEVVAADKGTAT------FSDIANGIAAEYGFWLGDAFASGGSAGGMGITAKGGWVSVQRHFRERGI---DVQKDNVTVIGIGDMAGDVFGMLLSDKLQLVAAFNHMHIFIDPNPDAAKSFAERKRLFDLLRSAKSITITPQMKARFDIAADKLAPTELLNAGIGTYVKSSKENDALRVDGRELRAKVV---GEGGNLGMTQLG-----------EFGLHGGASNTDFIDNAGGVDCSDHEVNIKLGEIVSGGDMTEKQRNKLLAEMTDDVSELVLGNNYKQTQALSLAERRARERVGYKRLMNALESAG... 1172
4 -11.300PF00670.21; SAHH_DICDI/191-351; S-adenosyl-L-homocysteine hydrolase, NAD binding domain  ali follow..  10  4................................................................................................................................................................................................GCRESLIDGIKRAT------DVMIAGKVAVVAGYGDVGKGCAQSLSKMGARVLVTE---------------------------------IDPINALQACMDGYQIVTMETAAPLSNIFVTTTGCRDIVRGEHFAVMKEDAI--VCNIGHFDCEIDVAWLNANAKKDTVKPQVDRYTLANILLAEGRLV............................................................................. 154
5 -7.220PF03949.15; MAO3_BACSU/274-535; Malic enzyme, NAD binding domain  ali follow..  11  3..................................................................................................................................................................................................GTGAV-SLAAVLSCAKASKVPLRDHRVVIFGAGTAGIGIAEQLREALVR-FWCIDRNGLLTDDMDQLLDFQKPYARSADEVKDYQRNGDGGGIDLL----------EVVRQAKPTILI-STVSGAFTEEIVKEMASHVKRPAILPMSNPTTTEGRALITTGSPFPPVEYNGVTYHIGQANNA-GLGLGTIV----------KSKLITDGMFEACARAIAGMVN--VGVPGAPMLPKVEDLRTVSATVAVEVAKTAM....... 262
6 -6.920PF01488.20; HEM1_PSEAE/169-304; Shikimate / quinate 5-dehydrogenase  ali follow..  12  9......................................................................................................................................................................................................................DLHRSQALLIGAGETITLVARHLFEQGVKRIVVANRTAEQFGAHAVLLSEIPEELANSDIVISSTASQLPILGKGAVERALKQRKHKPMF---VDIAVPRDIEPEVGE....................................................................................................................................... 121
7 -6.910PF02558.16; Q9K9R6_BACHD/6-154; Ketopantoate reductase PanE/ApbA  ali follow..  7  1............................................................................................................................................................................................................................VAVIGSGSIGLLLYAYLKLANWPALLVRPEQADHLNKEGLTFVA---------------------KSGEHQPISVTATPLSSFSAEEAEVGF-ITVKSFAVKALLPQLQRKKWDGLVFFQNGMTHLEILRQIPARAICCGIVEIGAKREDVRVQHTG................................................................................ 138
8 -6.240PF03446.15; Q8FTI1_COREF/15-184; NAD binding domain of 6-phosphogluconate dehydrogenase  ali follow..  10  1...........................................................................................................................................................................................................................QIGVVGLAVMGSNLARNFARNGHTVA--------VYNRSTDKTDKLISDYATDGNFIPTKTVEDFVAALEKPRRAIVMVQAGAATDAVINQLADAMEEGDI---------------IIDGGN-------ALYTDTVCREKEMAARGRHFVG--AGISGGEEGA----LNGPSIMPGGPKESWEALGPLLESIAAKV.......................................... 160
9 -6.150PF01262.21; Q9S227_STRCO/141-353; Alanine dehydrogenase/PNT, C-terminal domain  ali follow..  14  1....................................................................................................................................................................................APQVGAYHLMAANGGRGVLPGG-----------PGVLAGRAVVIGGGVSGWNAAQIAIGLGFHVTLLDKDITKLREADKIFGTKIQTVVSNAFELEKACL--------------------------EADLVIGAVLPKLVTNELVSRMKPGSVLVDIAIDQGGCFEDSHP---TTHAEPTFPVHNSVFMPGAVPNTSTYALT........................................................................... 174
10 -5.820PF00411.19; W0L7X1_9GAMM/19-128; Ribosomal protein S11  ali follow..  11  11...................................................................................................................................................................NTIVTITDRQGNALGWATAGGSGFRGSRKSTPFAAQVAAERCADAVK--EYGIKNLEVMVKGPGPGRESTIRALNAAGFRITNITDVT.............................................................................................................................................................................................................. 96
FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Jaroszewski L, Rychlewski L, Zhang B, Godzik A. Fold prediction by a hierarchy of sequence, threading, and modeling methods. Protein Sci. 1998 Jun;7(6):1431-40.