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Query: gi|6319259|ref|NP_009342.1| Protein of unknown function, localized in the nucleoplasm and the nucleolus, genetically interacts with MTR2 in 60S ribosomal protein subunit export; Ecm1p (YAL059W) [Saccharomyces cerevisiae], from S.cerevisiae

Results of FFAS03 search in PfamA32U
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MWEQRRQKVVFSLTILVRYRLKQSMAKKISKNSRAARQSDALEPEVKDLSELPRAEKTDLTNILIRTAAKNEALLEAKISKKANKSKRGKKLNKKALEDKLDNSISSMDRDRLVKALNFTNRLDGKIAKSISRAKYIQNTRKAGWDSTNETIKKELAFLNGGLSVQAKSASEGNAEKEDEEIPEVFDSLAEDNTVQKTPTNRFGVLPDDVEELast
1 -61.400PF09135.11; Q6CLT8_KLULA/8-125; Alb1  ali follow..  52  1..............................KHSRAARRSEAAEPEAKALETLPRTEKTDFAASLIRTANKNEQLLEAKLNKRGPRN----KKKSLGRVGKQQLDDSSLTSSKVMRVLNVNNRLDGKRERAIHRAKYVQSARKAGWDSTNAKI............................................................ 118
2 -6.830PF17671.1; G1QCS6_MYOLU/11-162; Family of unknown function (DUF5531 topsan)  ali follow..  13  53.....................................................................................QQEKTEKRKIPEAEPNCNAMSTREVERLHACFALQDKILERLMFSEMKLKVLENQMFIVWNKMNHHKRSSGQQ...................................................... 125
3 -6.510PF02516.14; STT3_SCHPO/23-509; Oligosaccharyl transferase STT3 subunit  ali follow..  13  365..ELRNEHVFIIIYSVLGTYFCGVMVRLVLTLTPCV---------------------------CIAAAVAISTLLDTYMGPEVEEDKVSEEAASAKSKNKKGIFSILSFFTSGSKNIGIYSLLSRVLVISSTAYFLIMFVYHSSWVTSNA.............................................................. 485
4 -6.450PF14963.6; H3DF96_TETNG/13-269; Calcium signal-modulating cyclophilin ligand  ali follow..  10  8..EIRRRKLL------SEERMNRIVGCTTNSSENHEPRFHLDLDRTEPVSSSSSPKRSSAHGSRSHSATPER............................................................................................................................................ 73
5 -6.360PF15048.6; H0X2K8_OTOGA/3-123; Organic solute transporter subunit beta protein  ali follow..  20  23LWFYRVEDFVISIALLRRSIQANRKQKMQPPEKETPEVLYLGEARIKDHNKLTNPSET.......................................................................................................................................................... 95
6 -6.280PF15142.6; G5BW93_HETGA/1-178; INCA1  ali follow..  10  3.............................LRCSRVVLRSPPASLPSQGLRLTPNRYGDITQRPSRVWMEEQYIPSMLRATGCSQLGSCPPPEGLPPPEMLCRRRRRPRLDRMQQGPGGIPARVRAHLEDLRRRQRTINEIKKAQW................................................................... 126
7 -6.100PF14023.6; B7FP83_PHATC/152-366; Protein of unknown function (DUF4239 topsan)  ali follow..  7........VLFAT--LTSTTISTLRMRQVEVLRAINMEAGELRVLESIVAVFPDGDLKDRCRNYLIQ----SRIIAESQPHS---GFVGDDFSSINPRRGMDSELNGFLQQLNLFTPDISSHLAEESYAALARLREQRYNR....................................................................... 132
8 -5.940PF01770.18; A0A1D5PVR1_CHICK/32-445; Reduced folate carrier  ali follow..  94VLAMQLMEFFYGVTMAARIAVAPSRYQRMASYSRSS---TLGSVSFLILNYVSLGFVTFGLFLTLFLERPKRSLFFNRAEAACNGAAPAELDKMAGGDKMDSGDKTDGGKVMGGWRQAVLCRMLREVCTVAKQSRLVLYYVQILWNDIYPARDNQR........................................................ 286
9 -5.830PF17534.2; Y028_MYCGE/1-186; Family of unknown function (DUF5453 topsan)  ali follow..  10  129LWSTTGTSIVLSLISIGMSKTAHFFIDIEILKAKKGEPTDPNKTDNRAV................................................................................................................................................................... 177
10 -5.750PF15352.6; G3SSS4_LOXAF/62-1039; Susceptibility to monomelic amyotrophy  ali follow..  10  1..QQRKQKF---------TERFQRAHIPLSQRKRAVFKKTVPPLE-EALKQI---QGSNLKSELNLPTSHRPIINWRAIDSALPSALSNRDQKHQTQLSSKVGCDKEMKENSRANLATNKDAFRLKLEET----KLLEDQHLSSLQKFRDEVNQITNSETLSSIDSLEAGECEE...................................... 159

FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Sikora S, Godzik A. Combination of multiple alignment analysis and surface mapping paves a way for a detailed pathway reconstruction--the case of VHL (von Hippel-Lindau) protein and angiogenesis regulatory pathway. Protein Sci. 2004 Mar;13(3):786-96. Epub 2004 Feb 06.