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Query: gi|6319278|ref|NP_009361.1| Cytochrome c heme lyase (holocytochrome c synthase), attaches heme to apo-cytochrome c (Cyc1p or Cyc7p) in the mitochondrial intermembrane space; human ortholog may have a role in microphthalmia with linear skin defects (MLS); Cyc3p (YAL039C) [Saccharomyces cerevisiae], from S.cerevisiae

Results of FFAS03 search in SCOP207
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MGWFWADQKTTGKDIGGAAVSSMSGCPVMHESSSSSPPSSECPVMQGDNDRINPLNNMPELAASKQPGQKMDLPVDRTISSIPKSPDSNEFWEYPSPQQMYNAMVRKGKIGGSGEVAEDAVESMVQVHNFLNEGCWQEVLEWEKPHTDESHVQPKLLKFMGKPGVLSPRARWMHLCGLLFPSHFSQELPFDRHDWIVLRGERKAEQQPPTFKEVRYVLDFYGGPDDENGMPTFHVDVRPALDSLDNAKDRMTRFLDRMISGPSSSSSAPLast
1 -7.760d1z06a1 c.37.1.8 (A:32-196) Rab-33b {Mouse (Mus musculus) [TaxId: 10090]}  ali model 3D-neighbors follow..  11  28...............................................................PDRTEATIGVDFRERAVDIDGERIKIQLWDTAGQERFRKSMVQHYYR---------NVHAVVFVYDMTNMASFHSLPAWIEECKQHLLANDIPRILVGNKCDLRSAIQVPTDLAQKFADTHS.................................................................................... 140
2 -6.060d4e70a2 c.66.1.0 (A:113-368) automated matches {Linum nodiflorum [TaxId: 407264]}  ali model 3D-neighbors follow..  12  32.........................................................................DGKDTPNAFAFAHEGKKVYEVCSEDANFSQLFSEGMAGDSWLFSREGLSSLVDVGGGTGNTS---VFDLPHVVSGPKQTHPNLDYESGNMFTDEIPHADAVLFKWVL------------CDWMLKQCKKALTKNGVKGK-ADHVLDHESCNDSNSMGTSLILDM--LFMSFLEGSLRTEKQWAKLFAEA....... 235
3 -5.600d2bk7b2 d.17.1.5 (B:99-217) Latexin {Human (Homo sapiens) [TaxId: 9606]}  ali model 3D-neighbors follow..  12  1..........................................................PDEEDNTFYQRLKSMKEPLEAQNIPDNFGNVSIWQNSTEDTWYKMVKIQTVKQVQRNDDFIELDYTILLHNIASQEIWQMQVLWHPQYGTKVKHNSRLPK............................................................................................................... 119
4 -5.480d2b3wa1 d.336.1.1 (A:1-160) Hypothetical protein YbiA {Escherichia coli [TaxId: 562]}  ali model 3D-neighbors follow..  12  1.........................................................MPVRAQRIQHVMQDTIDDYGDFSNFAAWPIKVDGKTWPTSEHYFQAQKFLDEKYREEIRRVSSPMVAARMGRDRSRKNWESVKE-------QVMRKALRAKFEQHAE-------LRALLLATAPAKLVEHTENDAY-WGDGGHGKGKNRLGYLLMELREQL................................................... 156
5 -5.390d1y5ia2 c.81.1.1 (A:1-1074) Respiratory nitrate reductase 1 alpha chain {Escherichia coli [TaxId: 562]}  ali model 3D-neighbors follow..  9  54......................TGSCSWKIYVKNGLVTWETQQTDYPRTRPDLPNHE-PRGCPRGASYSWYLYSANRLK--------------YP--------MMRKRLMKMWREAKALHSDPVEAWASIIEDGGFVRS-SWQEVNELIAASNVYTIKNYGPDRSYASGARYLSLIG-ASPQTWGEQTD-ESADWYIIAWGSNVPQTRTKGTKT-VAVT-----AEIAKLCDLWLAPKQGTDAAEFHLDNPSQYFTDYVRRYTDMP... 337
6 -5.390d1yw6a1 c.56.5.7 (A:1-322) Succinylglutamate desuccinylase AstE {Escherichia coli [TaxId: 562]}  ali model 3D-neighbors follow..  17  38................................................................................................................PLTPPQGALVISAGIHG--NETAPVEMLD-GAISHGEIPLRWRLLVILGNPPALKQGKRY--------------HSDMNR--FGGRWQLFAESGETCRARELEQCLEDFYDQGKES--VRWHLDLHTAIRG.......................... 152
7 -5.320d5mp0d_ d.113.1.0 (D:) automated matches {Human (Homo sapiens) [TaxId: 9606]}  ali model 3D-neighbors follow..  12  10........................................................................LDETLENVLLVQGYLAKSGWGFPKEEAPHDCAAREVFEETGFDIKDYICKDDYIELRINDQLARLYIIPG-NPKTRREIRNIEWFSIEKLPCHRNDMTP--KSKLGLAPNKFFMAIPFIRPDWLSRRFG.................................................................... 149
8 -5.150d3mksa1 d.42.1.1 (A:4-103) Centromere DNA-binding protein complex Cbf3 subunit D, CBF3D {Baker`s yeast (Saccharomyces cerevisiae) [TaxId: 4932]}  ali model 3D-neighbors follow..  18  1...............................................................................SNVVLVSGEGERFTVDKKIAERSLLLKNYLNDMGDDDDEDDDEIVMPVPN-VRSSVLQKVIEWAEHHRDS........................................................................................................................ 69
9 -5.030d1th0a_ d.3.1.7 (A:) Sentrin-specific protease 2, SENP2 {Human (Homo sapiens) [TaxId: 9606]}  ali model 3D-neighbors follow..  8  61.................................................................................VERNKKQGYPALHVFSTFFYPKLKSGGYQAVKRWTKGVNL-ILVPIHRKVH---WKCLKYLDSMGQKGHRICEILLQYL--QDESKTK----------------RNSDLNLLEWTHHSMKPHEIPQQLNGSDCGMFTCKYADYISRDKPITFTQHQMPLF............................ 212
10 -5.020d4z0ya_ a.86.1.0 (A:) automated matches {Coreopsis grandiflora [TaxId: 13449]}  ali model 3D-neighbors follow..  10  1.........................APITAPDITSICKDASSGIGNQEGAIRTRKCCPPSLGKKIKDFQFPNDKKVRMRWPAHKGTKKQ--------DDYRRAIAAMRALPDDDPRSFVSQAKIIQIHNSWLFFPFHRLYFYERI----------LGSLIDEP---------------------NFALPY---KWDEP....................................................................... 155
FFAS is supported by the NIH grant R01-GM087218-01
1 4 8 3 1 9   jobs submitted since Jan 1, 2011
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Ye Y, Godzik A. Multiple flexible structure alignment using partial order graphs. Bioinformatics. 2005 Mar 3;