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Query: gi|6319279|ref|NP_009362.1| Pyruvate kinase, functions as a homotetramer in glycolysis to convert phosphoenolpyruvate to pyruvate, the input for aerobic (TCA cycle) or anaerobic (glucose fermentation) respiration; Cdc19p (YAL038W) [Saccharomyces cerevisiae], from S.cerevisiae

Results of PSI-BLAST search in nr85s
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# E-value Template Links and tools%idFirst MSRLERLTSLNVVAGSDLRRTSIIGTIGPKTNNPETLVALRKAGLNIVRMNFSHGSYEYHKSVIDNARKSEELYPGRPLAIALDTKGPEIRTGTTTNDVDYPIPPNHEMIFTTDDKYAKACDDKIMYVDYKNITKVISAGRIIYVDDGVLSFQVLEVVDDKTLKVKALNAGKICSHKGVNLPGTDVDLPALSEKDKEDLRFGVKNGVHMVFASFIRTANDVLTIREVLGEQGKDVKIIVKIENQQGVNNFDEILKVTDGVMVARGDLGIEIPAPEVLAVQKKLIAKSNLAGKPVICATQMLESMTYNPRPTRAEVSDVGNAILDGADCVMLSGETAKGNYPINAVTTMAETAVIAEQAIAYLPNYDDMRNCTPKPTSTTETVAASAVAAVFEQKAKAIIVLSTSGTTPRLVSKYRPNCPIILVTRCPRAARFSHLYRGVFPFVFEKEPVSDWTDDVEARINFGIEKAKEFGILKKGDTYVSIQGFKAGAGHSNTLQVSTVLast
1 0.000e+00UniRef50_A0A2T2WLX5 Pyruvate kinase n=1 Tax=Sulfobacillus acidophilus TaxID=53633 RepID=A0A2T2WLX5_9FIRM  ali  36  1.................MRKTKIVVTLGPASTAPDVFRRLVDSGLDVARINLSHGAVDHHREVIRMIRRVEQE-AGRPVGIMLDTAGPEVRL-RTRTPQGLMLEPDATLSLGAGP------DADLVP-SIAGFEELLEKGHRLVIGDGNLVLEV--VQEGKPARVRVLQGGRMPDNKKVTSPGQAWALPVLTQEDVEALQMGIEEGIDWVAASFIRQPDDVVEVRRQVESWGGDIPIMAKIETKLAMENLDTIVRLSDGLMVARGDLGVEYPPEDVPWLQKKIIDAANAAGKPVVTATQMLESMIRANRPTRAEVTDIAHAVLEGSDAVMLSEETAVGDYPVEAVTVMARTAVASEAHPWDGDGTGHY-----GSDTVTDAVCHAALTAAEDLKARLIVTATESGHTAQSMAAHRPHVPILAVTPYERVARRLTLVWGLNTQIMNTHTT------LEGMVDESVAIAVKLGWATVGDRLIVTAGAPVGAGSTNVLRVVTV 463
2 0.000e+00UniRef50_A0A2H5W8P0 Pyruvate kinase n=1 Tax=bacterium HR11 TaxID=2035406 RepID=A0A2H5W8P0_9BACT  ali  34  14..................RMTQIVVTAGPACTGREVLAE----GVRVVRINAAHGTPDTHAEVVRAVREAARRL-GTSVAILLDLAGPKIRVGPL-DREPLYLQSGAEVVLVPG----STCHPGEVPVLYDALPAEVRPGHRILMADGMIT-TVVEAVRGRHVVTRVIHGGFLFSRKGVNLPDVPTGLPALTDKDRADLAWGVEAGVDLVSLSFVREAEDLRAVRRLLHSLGADLPVIAKLEKPQALQNLEAILAEADAIMVARGDLGVELPLEEIGIHQKEIIRQARRRAVPVITATQVLTSMIEQPAPTRAEVTDITNAILDGTDAIMLSDETARGKHPVEAVRTLRRVIERVEAFERTVRPLAPYRRDDVLP-SHQHAVCYAVYELAHRLDVRAILVPTWSGSTVRIIASYRPRQPILAFTPNERTRRLLSLVRGVQTFTVHAH------DDLATLVEEMKARARTEAGLPAGTPVVITGGVPLAPGQTN....... 473
3 0.000e+00UniRef50_A0A2G2JM43 Pyruvate kinase n=1 Tax=Blastopirellula sp. TaxID=2024826 RepID=A0A2G2JM43_9PLAN  ali  32  4..QLQDAKQISINSIANHFHTKIVCTLGPATESRSAIESLLAQGASVFRLNFSHSNYEWATKTADLARQVAASM-DRPLALLQDLCGPKIRLSHVGPQVS-EIEEGQVIRLTTDQFWNGEENKYDLSTNYEMLLNDVQVADQLLINDGRVALTVEEIYQDHLV-AKVTRGGKVEVRKGLNLPGVALSTPSVTEKDWQDLQWGIENQVEYVALSFVRESTEILEVKQALLDANCSAQVISKIERPEAIENIDAIIEASDGIMVARGDLGLETDFARVPLLQKDLIKRCRLAAKPVITATQVLDSMVETSIPTRAEVSDVANAILDGSDAIMLSNETAVGKHPEAVVRVIRQVAEQTESSVWKPEEFSDNHWGNQEAVADAAA------AAVLHMKAKAVVAFTESGRTARAMARYHLPVPIYAVTNNPATYRQLSLSYGIVPVFSPQIVS------VVQLLEEIDEQAKQRDWAQSGDWLALVSTFHETAKQVDTLHLHCV 493
4 0.000e+00UniRef50_A0A2E4MCD0 Pyruvate kinase n=12 Tax=Bacteria TaxID=2 RepID=A0A2E4MCD0_9BACT  ali  33  4..................NKTKILATIGPACSNQAMLKKMVDLGVNAFRINMSHGSIDDKKSLFKQLKEMPSDGGQRPT-ILVDLAGPKIRIKSVKN--RLILNENDKIIIGNEEDQ----DEEQITVSSGFTFGKISKGAKILINDGRIQLEVLKKINPHSVQVKTLIGGIVEKGKGVNFPGIAIDMPPLTEQDHIDLSLAIEEEADWIALSFVRSPKDKEIVTAALKDKGTSIPIIAKIEKWEALDHLDEIIDTFDGVMVARGDLGVEIPQEQVPLIQKKIISMANKSGKPVIIATQLLETMVESPTPTRAEISDIANAIFDGTDALLVTGETAVGKFPDKVVEVLNQVIVETEKTIDYSNILQPI----GHEHHTADAISHATCQIANDMNINIILSLTHSGSTARMIARYKPSASIIALTPVEKTYRQLSIIWGVSSKIINEYS------NTDDIPSVSTKFIDDNNILNKGDKYVVTGGVPIGAGTTNFVFVQKV 469
5 0.000e+00UniRef50_A0A1A8XXG9 Pyruvate kinase n=2 Tax=Candidatus Accumulibacter TaxID=327159 RepID=A0A1A8XXG9_9PROT  ali  34  1.................MRRTKIVATIGPATAAAEPLRQLLAAGVDVVRLNAAHSDMQTHSNNVRLVRELAGAL-GRHVAVLVDLPGPKIRTGLVVGDA-VELESGHEFLLSGTD--DGRGDVHHVATTLSELAQWARRGDEVYLADGAIVLRVLEAV-GNDVRTEIVRGGTLRSRKGMHLPRAEAHVEPFTDRDALALEMAIAAKVDFVGLSFVRRAEDVERVRAMLPKRGPRPALVPKIETAAAVDNIEGIIQVADAVMVARGDLGIQMPARRVPLLQKEIIRLCNLAGKPVITATQMLESMTRSPLPTRAEVNDVANAVLDGTDALMLSEETAVGLFPNETVRMMSEVAESAEG--WPHDRVDPAASAGADADRVAWAVAHAAVQAAEDLGVAAILCPTRSGQTAHRVAAFRPKVPIAGISTSPQVLGGLCLVWGVHPLLVAENLKS-------EQLPLAIAAARTAGIVRSGDLVAVVFGSAPRAGSTDSVRIVRV 470
6 0.000e+00UniRef50_A0A162RNJ1 Pyruvate kinase n=12 Tax=cellular organisms TaxID=131567 RepID=A0A162RNJ1_9CLOT  ali  45  1.................MRKTKIVCTIGPASESREVMCKLINAGMDISRHNFSHGNHDENRRKINLVKELRTEL-NKSVEILLDTKGPEVRTGKFADG-SVKLVEGTSYIVLCGDDIL--GDETTCSISYEDLYKDVNIGDYILIADGLVGLKVKEI-KGNKIHCIVKNTGTLGNYKNVNVPGVVTKLPAVTEKDIEDLKFGIEMGVDIVAASFIRKAEDVLEIKKVLNENGGHIRVFSKIENHEGVNNIDEIIEVSDGIMVARGDLGVEIPLEEVPFVQKMIIKKCNEAGKPVITATQMLESMNNNPRPTRAEVSDVANAVLDGTDAVMLSGETASGKYPVETVSIMSKIIKRTEKLQNYNYNIKY..................................................................................................................................... 346
7 0.000e+00UniRef50_A0A2N3AHQ3 Pyruvate kinase (Fragment) n=4 Tax=cellular organisms TaxID=131567 RepID=A0A2N3AHQ3_9BACT  ali  42  2...............SRMIKTKIVCTIGPASNSYEKIEKLIQEGMDVARLNFSHGSYEKHRQVIENIRRASLK-TNKSVAILQDLGGPKIRVGKIEKE-SILLKEGSSFILTNREV---PGDEQGVSITLPSLPQKVKKGDCIFLADGTLELKVKE-LTPTDIICKIVRGGELTSRKGINIPNISMDIPSLTEKDYQDILFGIKNKVDFIGLSFTRNAEDVLRARKILKENGADISLIAKIEKKEAIDNLKEIIEVSDGIMIARGDLGVEIPLENVPLVQKDIIKRCNLAGKPVITATQMLMSMVSGPRPTRAEVTDVANAILDGTDAIMLSEETAVGNYPLEAVEIMNKIALRVEKAIDYKKILSE..................................................................................................................................... 348
8 0.000e+00UniRef50_A0A0D6PCM1 Pyruvate kinase n=1 Tax=Acidocella aminolytica 101 = DSM 11237 TaxID=1120923 RepID=A0A0D6PCM1_9PROT  ali  31  2...............TTHRYAKIVATLGPSSTGYDEILALAQAGANVFRFNFSHGTHADHRLRMAFVREVEGVL-GHPLAVLADLQGPKLRIGSLEPG-HLDLAEGDQVIFTPAGKGDVVTD---IPLPHPEIFSAARPGVVLLIDDGKMRFEVVQADDGH-ITARTIVGGCLLPRKGVSVVGATLPVSALTPKDYIDLKVALELGVDWIALSFVQRPEDIDELRNL---AGPHVRIMAKIEKPSAVDCLEQIVERSDGIMVARGDLGVEMPVEMVPRIQRRILSTCRRLGKPVVVATQMLESMIAAATPTRAEVSDVATAIYAGADAVMLSAESASGRFPRQAVEMMASIIGDVEADEEFWKAAEKGR--VVSRANVSDVICAALRETAKALQPAAIVAYTTSGNTGFRASAERPRVPLLCLVPSLEVARPLCLSWGVRPRVTAKMNG------MTDVLKVANCLVLNEGVGREGQLLALTAGQPFGAGTTNVLRVERI 470
9 0.000e+00UniRef50_A0A1V9Z220 Pyruvate kinase n=1 Tax=Thraustotheca clavata TaxID=74557 RepID=A0A1V9Z220_9STRA  ali  30  34..............PASTKFTKIMCTVGPASETHDTLTQLIERGARVFRLNFSHGDFESHGKRLEAIRKASKALQ-IPVAICGDLQGPKIRVGSVPGGGLIHVKQGDTVVLSASKEAHLRDDIPVLALTYKDMVHEVEPGHLVLINDGAIRMRAIKAVYD-ELHCEVLVGGDITSGKGINLPESNIKAPAITEKDWACVEWAMKKDLDYLALSFVRNAHEVNELKSKLSKAKNRLHIISKIEKPQAIENINEIVEASDAIMVARGDLGVEMELAKVPIIQKLIIERCQMYGKPCIIATQMLESMITSVIPTRAEASDVANAIFDGADAVMLSAESATGSHPALVVETMGQIIEASESHIMTVVKENVPPTRTAAAHHLTASLAFGAWHVVQETKAKLVVCWSQHGNAARYLSQNDFKIPILAFSEIERTVHQMALFNGVTPVHMAVPSGTASFIDATEAL------LLQNNLVKKGDLVLFLGGRPLGSKSTNAMILHEI 532
10 0.000e+00UniRef50_A0A2H6HV86 Pyruvate kinase n=1 Tax=bacterium BMS3Bbin04 TaxID=2005727 RepID=A0A2H6HV86_9BACT  ali  33  8.............STASHHLTRIIATLGPASDSDDGVLTLIQAGTNIFRLNFSHGTYEQHAASVERIRRISA-LEGKITAILQDIPGPKLRIGEFA-EETVSVSEGQEFTLWVG--TDNKGDSSGVGFEREGWHSSIKPGERVLLGDGNMELNVVSVSDD-SILTTVGNSGEIRSRQGLNFPDTDLELGAVTDEDWDHIAFGLELGVDAIALSFVQGPEDLIEVRRFIQRKGDGPLLIAKIETPKAVENILEIIEQSDGVMVARGDLGITLPIERVPVIQKYLIQLAREQRRFVITATQMLESMTQAARPTRAEATDVANAVYDGTDAVMLSGETAIGRHPSTVVETMRRILTATEPSV-------KFPSMERIDESVDSAVSRAVKQLADELEAKAILAPISSGSTALRLSRQRMGVPILVGTLNDTLARRMVFYQSVFPMIVDPELGLKKTS------ECVIQNALDAGYITNGDRVLLSGGLPVKAGTTNFIRALTV 477
11 0.000e+00UniRef50_A0A0G1WF07 Pyruvate kinase n=2 Tax=Parcubacteria group TaxID=1794811 RepID=A0A0G1WF07_9BACT  ali  35  1.................MKRTKIVCTLGPASEDPATIEALVKAGCNVVRLNMSHGDYDWHECAIKNVRAAAKK-TGEPVAIVLDLQGPKVRLGEVHN-SQFTIHSGDRVVFTTSKVVIPRSTSSKIPIAMPNFHKYVRRGSHLLIADGTIECVVERVV-GHDIQTKIILGGELKSHKGIAIAGVSLPLPSLTAKDKRDVQWARVQDIDFVALSFVKRVEDVRALRKKLKAKLWMPAIIVKIETREAVRNFNEILCEADGVMIARGDLALATSPEEVPIIQKEIIEKCRQSSVPVIVATEMLASMEHSPRPTRAEASDVANAVIDHTDAVMLSGESATGQYPVETVATMAHIIKKTEQSRFDNLPIDPRLSLGDKRFSFGQGIALAASVLARTKGAAAIVASSLTGHIGRLLSSYRSEIFLFIGSPIPHVVRELNLSWGVRPFYVPK------AKTMDALLKYLLAHARQSGL-KKGSKAVFVGSKKLAPHASDLL..... 499
12 0.000e+00UniRef50_A0A1U7CTC4 Pyruvate kinase n=5 Tax=Planctomycetales TaxID=112 RepID=A0A1U7CTC4_9BACT  ali  35  13...................RTKIVATVGPASRDPAMLRRLAEAGVDVFRLNFSHGTHDEHTATYEAIREVNRVL-GRRIAVLQDLCGPKIRLGPIAGDV-VECELDAEFTLSKRPGATD--DPHQLTCTYESLADDLEVGQSILFADGAVAMDVVEHRTG-WVRLKVTLPGRIRSHQGINVPGASLSVSALTDKDLADLEWTVGREVSYVGLSFVRQAADVTRLRAELDSRGSRARIVAKIEKPQAVANLESIVAEADAVMVARGDLGVEIDVAKVPAVQKQIIDACHRSGIPVITATQMLNSMESSSRPTRAEATDVFNAVLDGTDAVMLSGETAIGAYPIEAVSTMSQIAHEAENGLYADDEPRRTVSRAGQVLPITEAVVAAASQVSQRLRAALLVVATHSGRTALALSKQRGSTPILALTDDVEVAHAMSLYWGVTPLHNPDLF------DTGQVLAFADEWCRERDLI........................... 475
13 0.000e+00UniRef50_A0A2H0C514 Pyruvate kinase n=1 Tax=Candidatus Peregrinibacteria bacterium CG22_combo_CG10-13_8_21_14_all_49_11 TaxID=1974796 RepID=A0A2H0C51  ali  35  42...............SSMPLTKIICTIGPASQEPEKLKALLEAGMGIARVNIAHGSEEQRRGLLQSVQNVSA-LSGRPIATLLDVKGPEIRTAD--RDEPLEVQQGDIVIFAPS---YGTADGKTVCVNYDAFAKDVRGCTQILVDGGALVFEVKQI-SGNEVHATAMTNGSITSRRHVNVPGAHISLPSVTEKDWHAIAMGIEEQVDFVAVSFVRSAADIELVRARLHEKSSSMKIIAKIETQQAVEHIAAIIDASDGIMVARGDLGVELPFESIPALQDDIVRLCRRTGKPVIVATHMLESMIDHPLPTRAEVTDVAHAASTYTDAVMLSGETATGQYPIRSVQAMSRILEETERARPSLSLDEHAC-----VHDEREARVHAALSMANALDCPAIFVCTRSGKTATALSMLRPRVPLYAFTPAEYIQRQLQLFFGIRPYCIP------FSDDPEETVTAALACIREEGVFPQGTRIVFVSDAKVSSGLVSSVQVRSV 508
14 0.000e+00UniRef50_A0A1F5VKQ1 Pyruvate kinase n=1 Tax=Candidatus Fischerbacteria bacterium RBG_13_37_8 TaxID=1817863 RepID=A0A1F5VKQ1_9BACT  ali  35  2................KLRKTKIICTIGPASESPEMLRELAVAGMDIARLNFSHGSHEQFKKIIAHIRTLNRELK-KNITILQDLQGFKLRLGTLND----KYLAQKNAILTLNDSIEQQV-KNDIPVMFPHLHKLLKPAQKVYLVDGQIELLVLEIKGNRIITC-VIKEGYISSRKGINIPFTTVTTPLMNEKDKQDAAFGVKENVDFIGLSFVRGRGDIQELRKYLKKFNAEKKIIAKIERREAVENIKEIIQEADGIMVARGDLGIEIGPERVPIVQKNIINLCNKEGKPVITATQMLTSMIEKPVPTRAEVSDISNSILDKTDAVLLSDETSIGKYPVEAVNVIHKTALLVEKRVSPD---ISLSRPCKKSTISPISVGDDVIRIAYDVSAKCIVAFTRTGFTAMHIAKHRPTLPVITFTNNETTRNELSLFWGMRHIFI--------ISSFENKLTQALPVLKQHKLIKQGDTLVLVS................. 450
15 0.000e+00UniRef50_D3E1S5 Pyruvate kinase n=8 Tax=cellular organisms TaxID=131567 RepID=D3E1S5_METRM  ali  34  1.................MKKTKIIASVGPASDSVEVMSDMVEMGMDCARINLSHANQEDILKIIDVVNEV-RKICNVPLAIMYDTKGPEFRTSEFKHGG-VLLNEGDTIKMS---KTCIQGNKEEFGVNHKEAIDFINVGDKVLIDNALLEFEVIDKKED-YVLLKALGDGKILNHKTINVPGVDLKLDFISDVDKEDISFAAGHSCDYLALSFVNSGEDVIAARKIVEDAGGDALIISKIESRMGLMNLDEIIDESDGIMVARGDLGVEVPMEHLPIIQKDIIRKCREKGKFAIVATEMLASMYESPRPTRAEVSDVANAVLDGTDCVMLSGETTIGKHPVHAVEMMDRICNYVESTIDYSKH-----TFYKGKVAISDTIAKLVIGASEYSDIKLIVTPTLTGFTARKISNLRSSSAILACCPSNDIARKLVLNFGVKAVITDIY------ENTDEMIDNVVDIAKMEFDLNKGDLIVVTGGFPLGKRNTNSLRILEI 467
16 0.000e+00UniRef50_A0A098G113 Pyruvate kinase n=85 Tax=Proteobacteria TaxID=1224 RepID=A0A098G113_9GAMM  ali  33  2.................LRRTKIVATLGPASKDPSTLRAMLSAGVDVIRINFSHA-AATALELITSARKIAEEL-NRPLAVMADLQGPKIRIGRF-KDKSITLVDGQFFTLDC-LATDVLGDQQGVSVAYPNLANELSVGDHLLLNDGVIELEVMQINV-HKIHCLVIEGGVLTDLKGLNRKGGGLAARALTEKDIEDMRTAIKAEVDYICLSFVKDAADILHARKLMQEFGATTPIIAKIERTEALEQLTEIIQEADAIMVARGDLGVEVGAAEVPAIQKQIIEQTRLLDKVVITATQMMESMISCPQPTRAEVSDVANAILDGTDAVMLSAETASGLYPVKVISMVNKICLSAEK---HASFFYDANAESCHYQRADQAIAMATMHAANHFPIQAIITLTESGDTALWVSRQHGTVPIFAVSANKRTIGRLSLVNNVYPIYLDFHQFK-----LEELHQQVINELVNLKHLENKGYVLLTRGQRIGPGGTNCMEIIHI 473
17 0.000e+00UniRef50_UPI000A96E3B6 pyruvate kinase n=1 Tax=unclassified Bacteria (miscellaneous) TaxID=49928 RepID=UPI000A96E3B6  ali  34  2.................LRRTKIIATLGPSSNTEEAITALVNSGVDVFRLNFSHSSAEEHIKTAQIIRSVEKKL-GLEVALLGDLQGPKIRIGEFENGK-ILLKENQLFTLDAGDKKF--GDESQVHIGYPKLPQEVNVNDVLVLDDGRITMVVENV-EGCRVICRVKNAGVLSNHKGLNRHGGGLSAAALTSKDIEDIKIASSIGVDYLAVSFPKSAADMYMAQQLMRTSGGDALLIAKIERAEAIEMLEEILSASDGVMVARGDLAVEVGDAAVPALQKTMIRMARSHYKISIVATQMMDSMVESPIPTRAEVSDVANAVLDGADAVMLSAETASGKHPITTVVSMAKVCVEAER---FSSPSFEKQIIDRRFTRLDQSIAMSALFAANHLSVKAIATLTQSGFTAMWISRINSGIPIFALSPRLSSRRKMKLFRSVYPLSIPNDIS-----DTQHCIIETEKALLREGVVSFGDTIIMTFGEPLGVGGTNTMKLLHV 472
18 0.000e+00UniRef50_A0A2R5G8T7 Pyruvate kinase n=1 Tax=Aurantiochytrium sp. FCC1311 TaxID=2023137 RepID=A0A2R5G8T7_9STRA  ali  38  201......................IVCAIGPASREVETLVDLLEAGMNVARLNFSHGDHAYHAQTIKNLQEAIRLREERHCAILMDTKGPEIRTGMLKDHEPVELVTGQLLEITTD--YTLAGTSSIVACSYKELCASVRVGGLILIADGSIQTRVEEIRE-TSVMVRVENDAILEERKNMNLPGVSIRLPGITAKDKYDLEFALNYPVDIVSGSFIRTAANVRAVRACLGERGKHIRVHAKIESVEALRNIEEIIEEADGVHVSRGDLGMELPLSKLFLAQKGVIRWANLAGKPVVTSTQMLDSMTTRPRPTNAECSDVANAVLDGTDCVMLSAETAKGMYPRESVATMGRIISEAERVINYESYYSTIRAESKGKVSVVEALASSAVETSLDVRADLIVVVSDSGDLARLVAKYRPTARIVVVTSNRVTAHHMSVCRGVSAMLLDEAVLSAPR----EMWLHANKYILDRAWARVGAMVTLVTS................ 663
19 0.000e+00UniRef50_A0A2E7G0K2 Pyruvate kinase n=73 Tax=cellular organisms TaxID=131567 RepID=A0A2E7G0K2_9EURY  ali  37  25.........LNI--GTIMRRTRIVATVGPACDSIEQLSLLIDAGADVFRLNYSHDQPEDKTVIYERIRQLENE-KERPIAILADLPGPKLRLGSFPG--VIQLRPGETLRLHCGTSKMSNPSPSDLPVDYDALPSEISIGDPILLADGLIRLKVVDTDSN-MIHCTIEDGGPVSSRKGVNVPGTIIDLPAIGPRDEAALNHALQNGADYIAVSYVRSVEDLKPARDTISLHNQHVPVIAKIEHPAALDNLDDILDYADAVMVARGDLGVEIPLESVPIAQQKIIDAGLSRGQPVIVATQMLESMTINPRPTRAEVSDVSTAIRHGATAVMLSGETASGDHPILAVETMAKIAQSSEESWTYEEG-----RPTSSEFRTTRAVAHAGVELARECGAVRIIVATEHGNAPRLVSGYRPGMPVTAVTDRVRAARRTCLLPGVDSVLVEEKTRGS------ETMLGALKVLAERGDIMQGDLVVSISGSPLARGATSTARLYRV 499
20 0.000e+00UniRef50_A0A2G9Z3D2 Pyruvate kinase n=2 Tax=Candidatus Moranbacteria TaxID=1752737 RepID=A0A2G9Z3D2_9BACT  ali  36  1.................MKKTRIIATIGPASDSKEVMKKIVDAGTNVFRLNFSHGTHESHQVIINQARELSRE-TKRPIGLLADLQGPRIRI---SVDKDLEIKKSEIIRISNFQTNSNDQISKIIFLDYPDIINDIAVGNKILIEDGIIRLEVVGK-EKEFLTAKVVNGGIIKNHKGVNLPDSELHFGAVTEKDKKDLEFALKNEVDFVALSFVSNAQEILEIKTILGRDADLPQIVAKIERKEAINNIDEIIGAVDVIMVARGDLGIELEESKVILYQKEIIAKCLRAAKTVIVATQMLDSMINNPIPTRAEVSDVSNAVIDHTDAVMLSGESASGKYPIEAVETMTKIIKDTEDSPFDDINPGYLDENIFNDY---ASIINSAHEMAKSSRAKAIVLFSETGFSARMIAHHRPTQLIIVGTYNLKTYNQMAMVWGARAYLFEEQ-------DREELIEQMININKEGGRLSAGDKIVVILGRIPG............ 473
21 0.000e+00UniRef50_A0A2S0KV66 Pyruvate kinase n=1 Tax=Victivallales bacterium CCUG 44730 TaxID=2094242 RepID=A0A2S0KV66_9BACT  ali  35  1.................MKFTKIVATVNASTCTPELLLALYKNGMDVVRFNTAHMEVGEMDRAVAMVRRVSDK-----IAIMVDTKGPNIRTANLT--EPLALKQGDTVYMTGDAVEAPAG----VQVNYPAFAAEVAPGSRIVCDDGAVELLVLA-REGKMLKCTAVHDGVLKNHKSVNVPDVELNTEALTEKDRRFIANAIELELDYIAHSFVRNAADIAAVRELLDAGKSPVRIIAKIENRQGVKNIDEILRAADGIMVARGDLGIEIPLEEVPLIQKELIRSCRKAGKPVITATQMLQSMQENPLPTRAEVNDVANAVYDGTDAVMLSGETAQGRYPVEAVSMMNRIVEEAEKS--SAGFFNHIDGVDTGGDREYDFMIRTAVDAAERLPIRAIVCNTAEGKSARCCAAYRPPVPVYALSYRRCVVRQLALVYGVYA------EYNEFMESTVELSKETARRLIAEKRLRPEDKVVMLSKNSQARETNNLLCLGEV 463
22 0.000e+00UniRef50_A0A1V6FCI9 Pyruvate kinase n=5 Tax=Terrabacteria group TaxID=1783272 RepID=A0A1V6FCI9_9BACT  ali  40  6..................KKTKIVATIGPASNTLEKVRELIDAGMNVMRINFSHGTYETHKIIIDISKQLIKEHIYIP--TMLDTAGPEIRCHFFENGK-VEIIKDSIVTIHMKEIL---GTATEFSVNYPKLVDDIHVGDMIKIDDGKLRLDVIEICKKRVIKVKAFNTHVISNRKGVNIPGERMTLPALSDRDRKDIKFGVENGIDLIAASFTRRAEDVIQLKEYLKELGPDIPIIAKIENKQGVDNINEILEVADGIMVARGDMGVDIPPEEVPVMQSDIILECRKIGKPVIVATQMLDSMQSNPLPTRAEVSDVATAIKEGADAVMLSAETASGQYPVESAAMQQRIAITMEQFLPYTQLANFGYNYSKKKRS--DAIATSVASTANLIDAKAIVCFSETGKSAIRISKSRPKCPIVMVTSDPAAGMRVAPYFGIFSIVVKTLPQL-----IEDMEAFALIKMRQLGL-KPNDNVIITGGTPTGTGSTNFLRIVAV 475
23 0.000e+00UniRef50_A0A2A2W532 Pyruvate kinase n=50 Tax=root TaxID=1 RepID=A0A2A2W532_9PLAN  ali  36  3............DTQRPFRHTKIVATIGPATETLEKLEALIEAGVDIIRLNMAHGSVEWVGEIIARIRQASH-HVGREVAIMMDVKGPEVRTGPV--DAPIELKSGDRLELHTQPFQLCDDGVHRVSVNYPDLPADVEVGATVLIDSGLLRTKVMQKT-DCSVVLEVITPGKLGSRRHINLPGTRINLPALTNKDESDLRAGVAAGLDFVALSFVRQAADIATLQAFLDELDCCAKIIAKIEDQAGVENMEEIIRQSDGVMVARGDLGIEIEYHKLPLVQTQLVNACQVQGKPVIIATHLLESMIQSPIPTRAEISDVSNAIREQADAIMLSGETTVGAYPLEAVEVLKNIVESIEPSVDGQINRRIQLHTPKAKML------RSAVVLAKELGHSGVVVFTRSGFLAYVLGAMRAEVPIYAFTDIPSTFHQLMLPWGVEPFLME------FSDDPEHTIQKALAQLKARGWATRGEWLVVITNALADDKIIDTLQLRQV 475
24 0.000e+00UniRef50_A0A2K3DST4 Pyruvate kinase n=2 Tax=Chlamydomonas reinhardtii TaxID=3055 RepID=A0A2K3DST4_CHLRE  ali  31 1803...........VSSSSPVRKTKLGFTMGPSCNSEDVLRQLVRGGANIARFNFAHGEMAAHQAMLNKLRTVCAA-EGRTVAVMLDLDGNVLRTSDLIDIKKIELQAGDKVELYGTDDTSPNADKVRIGVSLADLAECVKPGGLIRVHDGLITFEVVSVRPGGPVQAVVLNHAFLYARKPVHLVGVTIHSSFPAPADLEALAFALPNAIEFVAVG-VNSRNDVNAIRSFLDDNGGEIKLIAKIESEGGLRNLDEIIDAADGVILARGKLGMVVTPEKVALAQSVVVTKANVAGKPVIISRQMLESMVSNPRPTRAEMTDVANAVLDGASCLMLCSETSSGAFPADSFTTAVNIVRNAEHATSYASMHSFIRDFSAKPFNTIEAAAVALAQACMDSKLALCLVVSDTGEAANIVTKYRPPVPVMVVSSQPPVVAQRELCFGQFGYLASDGIVSAPAGDVRDLAADVVADARARGLCEPQRVAVMTGSSAMDVVHNAIVQIVEV 2306
25 0.000e+00UniRef50_A0A061REJ5 Pyruvate kinase n=1 Tax=Tetraselmis sp. GSL018 TaxID=582737 RepID=A0A061REJ5_9CHLO  ali  31  648................PIRKTNIIATLGPSSSSEEMIGRLLDAGMDVARFNMALMTMAEVKPIVKLVRKVAAE-KNRICAILVDTDGPQVHTCSLVESKSILLEEGQTVILMPDPAGNEPFTETRLRIKLPDLCKLVKPGMQVLIDDGNIKMEVVQVDEDVV-KAKVINHAELSSLMCCNILGVSLNLPVLTPQDRKDMEDAVEAGVDAVAASFVQSAEDIVYIRDLLTDMGGDIKLVAKIETIAALENLDDIIEQADGVMIARGNLGTYITPEKVFLAQNMITTKANVQGKFIILARHCLQSMVKNPRPTRAEMTDVANAVLDGVHCMMLSAETAVGHFPTESVLTMSAIIRNAESATNYTTQHMFIRDVTSKPFTTEEAVAAAAAKTPLDGSVSLVVVVTETGRMASLISKFRSSVPILVITTDPRVAACTRMEFAQYPCLVDNLGAS---EDIPTLIRGAVARARADGVYTTGSATVV................... 1122
26 0.000e+00UniRef50_A0A2A4JE60 Pyruvate kinase n=5 Tax=Obtectomera TaxID=104431 RepID=A0A2A4JE60_HELVI  ali  34  31.TPLDHVLNLDVKAPPACRLTGIIASMGKSTYDVDTLEKMMGAGMNTAMLNMNFGSREEHVECIKMLRTACKNFSIKPLSIAMRLSGRKIRTGRIAEGEAVELKSGEVVRLTTDETYKERCSTYTVYVDFMYFAEQMNKGDYILLDNETIMLKV-EMISSTTLTCKIERGGFLGSYKDVFVPNVVLNMPNYTDKDKLDIEMAINNQVDVIIAAFVNTASCILELKAILGEKGKKLAIVANIQTIEGFRNFDSIMQEANGVMISRQELGSDITPKKLVIAQKNMIARANRVNCPICVSAHILSSMRFKKIPLRAELLDIANCILDGVDSLVLCAETAVGQYPIEAVAVMSSTCKEAEACVWTKQVFYDFIDKTPLPCDQLTGAAMAGVLAAQRSIAAAIIVVTTSGKSAQTVAKFRPRCPILAVTRYALVARQLHMWRGIVPVIYEDAPETEWPVDLEKRVNFCIKWAVERGFIRIGDPIVIVSGWRQGSGFTNTMRVV.. 534
27 0.000e+00UniRef50_A8J345 Pyruvate kinase n=2 Tax=Chlamydomonadales TaxID=3042 RepID=A8J345_CHLRE  ali  28  649.........LIIERQFNHRSTKIFASLGPASYDPKKVEAMLDNGVSVFRI-FLHEAPDFYQKLVDRLREQFEQRREKCSYTTMP--------GLMATIKTVVLVP------TSDEGFTGADGIHIVGVNFPTLTAKLRAGDVLVLAEGTISLTVKEVVPHGKVITKVTTAAKLGEDRAIDLAGGCLLQDFLGDRDCEAVLFCAKNMIDFVSIPNVRSRADVMAVRELLDANGGRCKIISHVSTAKAIANYDEILDATDAVLISRAYMGMRIPAAKVSLAQKWMTAKANLKGKPCIVSAQIMYSMVDSPRPTRAEMTDVANALYDGADALMLREETAVGSFVERVVSITADILRDAEVGVDTYAQLNQLRNFTPKPMPTLECLCSSAVKAAVDMRAALIAVITDTSAPVRALAKYRPGQAIVVVTTRTHVARQCNMNYGCVPLLLRSKDRDAP---LDKIVSKIVDFARTQKLADQGDQLIIVQG................ 1135
28 0.000e+00UniRef50_A8JDY0 Pyruvate kinase (Fragment) n=2 Tax=cellular organisms TaxID=131567 RepID=A8JDY0_CHLRE  ali  46  19.................VRKTKIICTAGPACWSEEGLGKLLDAGCNIVRLNFSHGDHEGHFSVLQRWRKVCAE-KDSHAACLLDTKGPEIRTAMLKDGKDIELVANQKVTIHAGYKDAATG-ETHIGLSYGKLCSSVKAGNRILLADGSISIV---IVDGTTLIGTVLNTKKLGQRKNCNLPGVKVDIPVLTKKDIDDLQFCVKHKMDFVAASFVQSQQDVLYIRSILDDAGKDVKIISKIENAEGLKNFDEILEVTDGVMVARGDLGMEIPVEKVPLAQKMLITKANIAGKFVICATQMMESMITNPVPTRAEMTDVANAVWDGVDAVMLSGESANGAYFGQAVETMARIARSAEIGVNFYQSFDYTHKFTPKPVSAVEAMCSSLAKNAVDIRPGMIVVFSEGGKVARLVAKYRPCAPVLVV............................................................................. 421
29 0.000e+00UniRef50_D6Z321 Pyruvate kinase n=4 Tax=Bacteria TaxID=2 RepID=D6Z321_DESAT  ali  34  9............EQHRLLRKTKIVCTIGPKTASFEAIKGLAELGMNVARLNMSHGTQDWHLGVIKNIKRYNKKFAG-SLAIMLDTRGAEIRSGDLKQD--LALKVGDILTLTTRRQAELE--PYCVEVSHDGFVAEVAPDDIILVDGGMLRLRVLGVGR-TDIRCQSLDEGVLSSRRHLNVRGKSAELPTITEQDWRDIEFGIDQRVDFIALSFVREAGPIVDLQKRLQARGVAMEVFAKIESAASIPELDDIIAVADGVMIARGDLGAELPYEDVPLLQDEIIAKCRRAGKPVIVATHMLESMIVNPTPTRAEVTDITHAVQQGADAIMLSGETATGRYPRKALEVMGTVAGRIERHLAAGSAP--FLSAREDRLRPKREIAHSAAMLSNNLQAVGTLVITRRGLMAALLSQCRPRGPIFAFTNTTHVRRRLGIYWGVQAFVV------ALSSDPEVTIQRAIEQLLRKGVVRSGEKIIVLSDILAGGKFVETVQVRVI 482
30 0.000e+00UniRef50_A0A2E9CGN0 Pyruvate kinase n=2 Tax=Candidatus Heimdallarchaeota archaeon TaxID=2026747 RepID=A0A2E9CGN0_9ARCH  ali  35  10...................KAAIVGTLGPSSSEEEKLRKLIDNGLDVVRLNMSHGNIEDHKERFELVRRVDET-----IPIIIDLSGPKIRIGEVK--ENFDLIKDDNIILTKENVV---GNKEKLSISYNELIDLVDVKDTLFINDGIIELEVTEKFEN-ELNCKVISGGPISSRKGLNAPGVPIGLFSPTKKDLEDIQNTINLEPDFYSVSFVRRKEDLIKVREQIANFTTRVPLISKIEHQDALDNIDEIINHSDGLMVARGDLGVELPPEDIPLIQEVLVKKSNDAGIPVIVATQMLESMVNSAKPTRAEASDVANAILQGADAVMLSAETATGNHPIEAVGMMERIIKKVE-----PRLFEKSIELQRYVNSIPDSIGRSAVSMAEALNADVIMAFTRSGGSSQSVAKFRPNQKIIAVTPLDKTSRRLRLQWGVNPLLLSRDFS-----DTDEMIFQGVNSAYEKGFVDKFDTAVLVAGSLLGPTSTNLI..... 466
31 0.000e+00UniRef50_A0A2H0L1V5 Pyruvate kinase n=1 Tax=Candidatus Peregrinibacteria bacterium CG11_big_fil_rev_8_21_14_0_20_41_10 TaxID=1974792 RepID=A0A2H0L1V5  ali  32  2.................IKNTKIVATIGPASNSLKILKQMITHGMNVARINASHGNHKQHKEIIENLRTA-EKATKSNIGILYDLQGPKIRIGDLDKEG-VTLKKGEKIILHDGQAYIEKHGQKYIPIQYKPLTHAVEVDEPILIKDGLVELKVLSHNHKTQVECEVIAGGLITSKNGINAPKTALTSAALTTKDKADLEFASSADVDFIALSFVRTSADLALLRTECKKLKFTPSIIAKIERPEAMENLEEITKNADAIMIARGDLGIEIPAAKVPLAQRKIIMVANKFGKPVITATQVLNSMVNNPRPTRAEVSDAANAVFDQTDAIMLSNETAVGEYPVETIHILNEIIQSIETELRTNKELAHASHYQFKNLNPLKAITLNALELAMDLDAKVLVAVTKSGYTANQLAKYHSFLPIVVYTPNKQIKRQLSLTWGINEIHIKKEIDPTNPTP------FLREDLIKQKLVKKGDEVVV................... 458
32 0.000e+00UniRef50_A0A2D7U0B1 Pyruvate kinase n=3 Tax=unclassified Alphaproteobacteria TaxID=82117 RepID=A0A2D7U0B1_9PROT  ali  34  4..........NTRSGQTWRATKILATLGSASESEAQITQLVQAGVNIVRMNFSHGTHEEHLKRIEMVRAIEKKLS-QPIGILADMQGPKYRIGRVVDG--LSLVEGSLIQF---DQSDEIGNAERLPLPHPEIFKALYPGARLLMDDGKLALVV-KTLADNAFTAEVLTGGPVLSRKGVNVPDIKLDTDVLTSKDLKDLEFALDKGADWIALSFVQSVSDVLAAKAKIA---GRAQLMAKIEKPAALAEIQDIINASDAIMIARGDLGVELDAAEVPSVQKRLIYQCRKVGKPVVVATQMLESMIHSPTPTRAEATDVAGAVFDGADAVMLSAETAIGDYAVEAVKTMASILTSAEMHI--KEFPFDGPAPLDVEPSIYHAVAKAAVALAQTIEAKAIIAYSASGNTAVRIARERPAIRLFVSTPELAVQRRLSVLFGATTLR-------QAESDYEAALSITKETLKQEKVVNTNDAIVVVAGFPFGAGSTNAIRVEHI 475
33 0.000e+00UniRef50_A0A2K3DV78 Pyruvate kinase n=1 Tax=Chlamydomonas reinhardtii TaxID=3055 RepID=A0A2K3DV78_CHLRE  ali  29  731.........LIIERQFNHRSTKIFASLGPASYDPKKVEAMLDNGVSVFRI-FLHAPTDFYQKLVDRLREQFEQRREKCSGLMATIKGPEVRTTLLRNHAPLRLATGETVVLVPTSDPLFEGGIHIVGVNFPTLTAKLRAGDVLVLAEGTISLTVKEVVPHGKVITKVTTAAKLGEDRAIDLAGGCLLQDFLGDRDCEAVLFCAKNMIDFVSIPNVRSRADVMAVRELLDANGGRCKIISHVSTAKAIANYDEILDATDAVLISRAYMGMRIPAAKVSLAQKWMTAKANLKGKPCIVSAQIMYSMVDSPRPTRAEMTDVANALYDGADALMLREETAVGSFVERVVSITADILRDAEVGVDTYAQLNQLRNFTPKPMPTLECLCSSAVKAAVDMRAALIAVITDTSAPVRALAKYRPGQAIVVVTTRTHVARQCNMNYGCVPLLLRSKDRDAP---LDKIVSKIVDFARTQKLADQGDQLIIVQG................ 1238
34 0.000e+00UniRef50_B3DX02 Pyruvate kinase n=94 Tax=Verrucomicrobia TaxID=74201 RepID=B3DX02_METI4  ali  30  2...........IPFKNWKRRTKIIATLGPATESGEKIFSLIEKGVDVFRFNMSHGNPNWVREKVGLIQEFSKRLS-KYVGMLLDTQGPAIRTGDLPD--PMQLKPGDSFTFTVRGEKTD--DLHSVSVNYDDIVNDIHVGDVMLVDNGNIQMRVIAK-EKNILRCEVLTAGVMKSRRHINIPGVRINLPPLTQKDLRDIQLGIECGMDFFALSFVREANDCDLLRQILISKGSHGKVVAKIEDQLAVKNLSQIIDSSDAIMIARGDLGIECPFEELPIIQRRIVKSCIQKRKPVIVATHLLESMIMNPAPTRAEITDIANAVYEQADCIMLSGETASGKYPLECIQVLDRVAVRTEKSGGAGYA------SLVELFDDEEKLAKTAVHLADDVGAPAICVFTRFGHLATLIAGLRPRSLIYSFCPDEDVCRKLTLHYGVEPCLV------VFPKSQEESIELVESYLKKKG-IESGQKIVLISEVPLRGERDRYILLHQI 472
35 0.000e+00UniRef50_G0ELM6 Pyruvate kinase n=20 Tax=Brachyspira TaxID=29521 RepID=G0ELM6_BRAIP  ali  34  1.................MRKTKIIATLGPRWSSEDMVRKIIENGADVCRLNFSFGTYDEHLERINIIRKVSSELK-KPVAILADLQGPKIRIGKLK--EPITVKEGDIVKLS---GYKETNDDSIIPTTHSNIAHDVKSGSMLLIADGTIQLIVESSDEAKLVVCKVITGGTILSSKGINLPGAHVTTEVLTEKDVSDALFAAKNGVNYLGMSFVRKAEDVIRLRKILDDNNQDVGIVSKIENTESLENLEEIIKHSDGVMVARGDLGVEIPFGEVPVWQKKILRMANDIGKITIIATQMLESMTKSPVPSRAEASDVANAVLDGTDVVMMSAETASGDYPIESVKAMVSIVEAAERS----AIRYSHDNMSYLDRGVNDALTDSASYLSYCLDNKVIIALSRSGYTVKNLSKKRPKTPIVFMSADTDLCNRLAICHNVYTILMPEDLNFSAGISHGGQIDILEDTLIKHNLANHGDKAILVSGSKWGRWQENSVRVVVV 476
36 0.000e+00UniRef50_A0A2D7XRP4 Pyruvate kinase n=1 Tax=Ponticaulis sp. TaxID=2020902 RepID=A0A2D7XRP4_9RHOB  ali  34  7............NSLARLRRCKIVATVGPSSSSPSGLALLARTGVDVFRINFSHGSREDHKKVIAAIRQ-MEPMIGRSVAVLADLQGPKIRVGTLQDG-SFEFVWGEEIDLVCTAEQTEG--EKFVPIPHPEIFEVSEPGDKLLFDDGRLGVELVSVSADRAV-AKVTMPGTLTNKKGVNVPDKRLKISAVTDKDKLDMQTAIEAGVDFVALSFVQHPDDIKEAREL---AGPEARILSKIEKPSALEYLEEIIAASDAVMVARGDLGVEMPAEQVPVHQRRIVRTARQYGKPVVIATQMLESMINSPVPTRAETSDVATAVYQGADAVMLSAESAVGRHPQTVVAIMDRIIRAIEQAEDYHISLE--QYTADPDNTTQDAICHAAADAAETLKCKAILAFTSTGSTVKRLSRARPLIPIVMLTEYVTTARRGALYWGVIPLV------QSDIGSYEDMVKTGKQVASDLG-ADPDDRIVITAGYPFGPGKTNLLQVTRV 478
37 0.000e+00UniRef50_UPI000428A1E6 pyruvate kinase n=1 Tax=Desulfobulbus japonicus TaxID=231447 RepID=UPI000428A1E6  ali  38  5..................NKTKIVCTIGPASRSPEILEKLLTAGMNIARLNFSHGEFEQHKKDIEQIKTVATRL-GKPVAIMADLPGPKIRIGDLA-EEEIELLTNQDLILTTKTVI---GTTEKISVNLPNLHEVVQAGSYIFLNDGFIQLKVKAI-KDRDIHCLVVVGGPLRSRKGLNVPDVDLGIDILTDKDKEIAAFALKNGVDALSLSFVEKGEDIAQLRQVATCLGYDPFIIAKIERSQAIKNLDDILKQADGIMVARGDLGVEIPIARIPIVQKMIVQKANLMGKPVITATHMLESMIHNVIPTRAEATDVANAILDGTDCVMLSGESAVGKHPVVSVTTLSDIAVEAENLRSTKK--SDTATITSPTICSLDIIASSVEASVYRLSPAAVFVPTRSGATARNIARYHLPVWVVGVSSKEKSYKDMVFSYGVIPVH-EPDHPTNWRKWIEA-------KLKEYGF--NGNWVILTEG................ 452
38 0.000e+00UniRef50_UPI000996D6F8 pyruvate kinase n=3 Tax=Alphaproteobacteria TaxID=28211 RepID=UPI000996D6F8  ali  33  5..................RRAKIVATVAPASGSPFMLRTLFTKGVDTFRLNFSHGEHAIHAATVDAIRALEREV-GVPIGILQDLQGPKIRLGRIAGGER-TLERSEKIALVAEDTTDSL---TEIPLPHPEIFDAIAPGHRLFIDDGRVQLTVVAKAPGR-IEAEVLQGGKVSDRKGVNLPDCVLELPVLTEKDRGDLEYGLSLGVDWVALSFVQKASDIDALRAIV---GNSVGIVAKIEKPSALDEIEAIVRKSDAIMIARGDLGVEIPPEQVPARQKEIIALCRRECRPVIVATQMLESMTSSPAPTRAEASDVATAVYDGADAVMLSAESATGAFPAEAVEVMDRIIRSTEAHSFYAKSIAASREPAP---TPADMIADTAATLACSLQSKCILAYSVSGATGVRIAARRPKLPLILMTRDERVSRRMALVWGMRSI------QEPSIGDYNSMVATAKDECARLLSPAIGDTMVVLSGSPFGVGSTNNIRVAT. 468
39 0.000e+00UniRef50_K0T143 Pyruvate kinase (Fragment) n=1 Tax=Thalassiosira oceanica TaxID=159749 RepID=K0T143_THAOC  ali  39  58.STMSYQSSLEYTSKKNPQLSKIVATIGPTSEQLPVLKDIVRSGMRVMRLNFSHATVEEVELRMKNLKASESSIHKNVRAVLLDTRGPEVRSGKLAGDTSVNIEAGSTVALRTTDEYRENSTASDLFIDYPKLAKCLVPGMKVLLDDGAIILTVTEAEAGKEVYTTADNSGEIRSRAGVNLPGAETDLPAMSEKDKIDIKYGMTKDVDYVAASFIQNAEGVREIRAYMEEAGHPLPIISKIESVSGLKHFDAILEESDGIMVARGDLGVEIPIQQVTNAQKEMVAACNAAGKPVIVATQMLESMAKNPRPTRAEVADVTNAIYDGADCVMLSGETAKGKYPVQVVQTMNEIIASAEHFTKYSFPDINLAQLNREDRSVEASIAKAAVTAAEERDATAILVLSCEGNLPRMIASFRPNMPILSFCPSAKVARQLMCNRGIHPIHIDDLFDVPTTK----RAGSAIQYAKQFGMLQEGDNVAVVTLEPADNELSSSMKVVTV 602
40 0.000e+00UniRef50_A0A2E5EMU8 Pyruvate kinase n=2 Tax=Bacteria TaxID=2 RepID=A0A2E5EMU8_9BACT  ali  29  1...........MNRKHQFVLSKIVATLGPASSDVEAIGELIQAGARVFRVNFSHGTFDDFDRMLKNVREAAKE-EDRFIGVLGDLSGPKIRVGKVVDEG-VQLEAGRTVRFVSEEATQTPGEPVVFSVTQGGFLDDVCEGQRVFLDDGNVRLTCVEKTGGAFLECTVEVGGKITTGKGINLPDTDLSLPSLTEWDHKCIDFAVDAGFDFLALSFVRRAEDVKELKHRLRELGARPKVIAKIEKPQAMEHLDEIVEEADVIMVARGDLGVEMDVAEVPVCQKEIVHTAHHRGKPTIVATQMLQSMIESPVPTRAEATDVANAIFDGADAVMLSGETAVGKYPVETVKTMRRINRKANDHRLERGMEFRQPANIREGKFRTAALAHGVKVISKDLDAKLIVLWSELGGGASYMAQNKLPVPVITFSESTSALRRMSLLYGVVGRKMQR------PKSADTFLHAVDDLLLKNDWATRGDPIVVVMGEPIGAGLTNKILIHHV 513
41 0.000e+00UniRef50_A0A179D5M3 Pyruvate kinase n=1 Tax=Thermosulfurimonas dismutans TaxID=999894 RepID=A0A179D5M3_9BACT  ali  36  7...................KTKIIGTIGPASASRKVLQQMIQAGMSIARLNLAHGTPELHEQYIALVR-AAARTAGRKVAIMADLPGPKIRVGVLP-EEPLELKKGARIFLVPHERTN---DPRTIPIPLPGLLEILRPKHSVYLNDGLIQLMVEEVLRDKA-RARVVVGGELFSHKGVNFPGIDLGLSAFTEEDQRLMSFALAHGVEAISLSFVEGPEEIRKAREYARSLGYSPFIIAKIERAQAVKNFSAILEEADGIMIARGDLGVEIPIEEIAVVQKSLIEKAALAGKVVITATQMLKSMTHNRRPTRAEVTDVANAILDGTDCLMLSEETAAGLYPVEAVKMMAKIAIVTEKERKYFPVRENLLASHKGKISLDDVLSLDVFTTVEHLKVKAIIIPTDTGATARKVARFRLPVWIYAFSPHESTCERLLFYYGVRPALLTESLSDWQG--------FALHWLRKN-ILKEG-LVVSLQRTFLGSHKTYRLELIEV 472
42 0.000e+00UniRef50_A0A2A5HVN2 Pyruvate kinase n=3 Tax=Alteromonadales TaxID=135622 RepID=A0A2A5HVN2_9ALTE  ali  39  3..................KQTKIVATVSDLKGDVEFIGELYKRGVNVIRLNTAHQTPEDTRKVIENVRKVSEKL-----AVLVDTKGPEMRT-NLKIEKDLEIRTGEKVIFRSDG-LDVATTASAVQVNYLGFVQDVPVGARILIDDGLLELEVDSK-DDEALYTTALNNGKIKKKKSVNVPGVEIRLPSVTERDKTFIEMAIEARVDFIAHSFVRNKQDVLDVQNILDAKNSPIKIIAKIENREGVDNLDEILEVVYGVMVARGDLGIEIPGEEVPLIQKDMIQKCIKAHVPVITATQMLESMIQNPRATRAEISDVANAVLDGTDAVMLSGESAYGDYPFEAVETMARICSHVEDKAASGIYLDD----KKEGNNLQNYIAKSAVKAARDLDISAIVVPTRQGSTARQVAAYRPAAPIYAACYEAGPLRLLSLSFGVEAYLIDAPGRSC-------VVTKALAPLLEQGVVTDESLVVVAASAPNSPGETNRLEVNTV 466
43 0.000e+00UniRef50_A0A2E8UNH3 Pyruvate kinase n=8 Tax=Verrucomicrobia TaxID=74201 RepID=A0A2E8UNH3_9BACT  ali  34  5..................RQTKIIAPLGPATATSEAISSLIEAGANIFRLNMSHARHDWAATVVGHIRQSAA---GRPIAILADLQGPAIRTGTV--EPSFQLEAGQSFVFYTDERPPGP---QSVSVNYPGLANDLNPGDTILIDNGLIRMKVLAEAEGT-IECEVLVGGEMGSRRHINLPGVKVNLPALTQKDHADIECVLGLGVDFIALSFVREAGDIAQLRDAIANVDNPPRIIAKIEDQHAVQHLDPILKATDAIMIARGDLGIECSYEELPIIQRRIAKLCQQRGCPVIVATHMLESMIEKPHPTRAEVTDVANAVYEHADAIMLSGETSVGKFPDTCVEVADRIARRIERSGGANYH------QSAQLDDTREKLAHSAVRMADDLDAAALVVFTREGRMVPEAAWMRPRASILALCLNEPVARAFALHRAVQPVVLP-----WDEGDPDEVTDFALAELAKREILKTGDTVVVISSELAVESIADSIQMRTV 467
44 0.000e+00UniRef50_A0A212FH64 Pyruvate kinase n=11 Tax=Ditrysia TaxID=37567 RepID=A0A212FH64_DANPL  ali  34  31.TTLDHILNLNISAPAGCRLTGIISFMGKSTYDVEVMQKMIAAGMNIALLNLSFGNKEEHMETIKNLREAVKNYKKYPLAIGARLPGRKIRTGCIADGETVELKTGEVVRLTTDETYRDRCSNYTVYIDFMHFAEQMDKGNLVLLDNETIKLKV-EMISATTLTCKIERGGFLGSYKDVFVPNVTFDMPNYSEHDKEYIDMAIHMQLDILVASFVNSSNTITELRLLMGEKGKKIAIVANIQTIQGFHNFDDILSAASGIMITRQELGSDITPKKLVIAQKNMIARANMANIPICVSAHLLSSMRHNSIPLRAELLDIANCILDGADALVLSAETAVGDYPVDTVECMATTCKEAEACVWTKQVFHDMFDKTPQPCDQATGTALAAVIAAQRCLAAVIVVITTSGKSAQIVAKYRPRCPIIALTRYAAIARSLHMWRGIIPLIYEAGPAVDWQMDLENRVHFCTKWAMEQGFLRIGDAVVVVSGWRQGSGFTNTTRII.. 534
45 0.000e+00UniRef50_A0A0D8FYA1 Pyruvate kinase n=3 Tax=Acidimicrobiaceae TaxID=84994 RepID=A0A0D8FYA1_9ACTN  ali  34  5..................RRTKIVCSIGPASQEVDSLVALIEAGMNVARVNMSHGTFAEHSTTIDNVREAA-RRTGQIIGILGDLCGPKLRITGLP--ARIHLKPGDQFMLSEGD---PEEDVDAITITPLGVLTEVARGDSIAFADGAVRGLVQERNE-HGVSVLVTQGGSLSIRKGVNLPDSHLSIPAMTDKDFHDASFLLEHNVDFLALSFVGSASDLTIAREFMNAHGPNIPLVAKIERRDALGRIAEIMDVADAVMVARGDLGVEIPVEEVPIEQKRIIHLANARGKMVITATQMLESMISAPTPTRAEASDVANAILDGTDAIMLSAETAVGSYPVDAVGQMDRIARATEQIV-TDQSLTLLTHPVRAIHSTADAIGFAAADLSRNLALKVVIAVTESGHSARTISRYRPNVPVVGATPDEFAARSLTLSYGVIPAVIPRSPS------TEVMIQEAIDAAIDLDLCETGDLCALAAGIPFGVGTTNLVKIQVV 477
46 0.000e+00UniRef50_A0A2M6X9R7 Pyruvate kinase (Fragment) n=1 Tax=bacterium (Candidatus Torokbacteria) CG09_land_8_20_14_0_10_42_11 TaxID=2014298 RepID=A0A2M6X9  ali  36  4..................KKTKIVCTLGPASSGMETILAMLKAGMDVGRINFSHGTYEANSALLRNVRGAACAL-GKSVAVIQDLQGPRVRTSNIPKGG-LTLRPGEIVTLSSPSQKKNQEKLKVFQVTYKKLDQDLSRGKIILIDDGLFKLKVL-YARKKEIKCRVLSGGILTTGRGMNFPGSSLGLSAITAKDRKDLEYGVKLGVDFVALSFVQSAKDILDLRRLIKRLNPRTKIIAKIEKEEALNNLGEIIEASDGIMVARGDLGIETDPARLPLAQKKIISQCLVAGKPVIVATQMLDSMQENPRPTRAEISDVANSVIDHADAVMLSNETATGKYPVEAVEFMARTCIETERSRYDDIIYPSRPGNND--LSPVPALSQAACLLAASLRAKVILVTTRSGFSVRAITSHRPNNSLVALTSSPNVYRELALCWGARPYL------AQQFSDIESLIGYGL.................................... 447
47 0.000e+00UniRef50_A0A1G3MYP5 Pyruvate kinase n=6 Tax=Bacteria TaxID=2 RepID=A0A1G3MYP5_9SPIR  ali  35  5..................KLTKIVATISDSRCDEAFIRSLYEAGMNVVRINTAHQTPEASATVVKTVRSVS-----PNIAILVDTKGPEVRVRGL--EKPLELKTGETVTIPRVDELRKGFD-----VSYDAFVSEVPVGARILIDDGSIELAVKSTAPG-MLLCEVQNDGIIKDRKNVNVPNVPLHIPALSNKDRDYLKFVAAHAIDFVAHSFVRNKEDIIEVRKILESHGSKARIIAKIENSQGVTNILEILDYADGAMVARGDLGVEIPFERLPGVQKFIIASCIKRGKPVITATQMLHTMIEHPRPTRAEVSDVANAVFDGTDALMLSGETANGKYPLEAVQTMARIARQAES----QKPRAEHIESEATYNHVRLYLARGAAMSAIRLPVKAIIADTETGSIARVVASYRSHVPTYAFSPQISTVRSLALSFGVYSEL------SPTFDNASSLVSQSLKSLVERGMIDEEDLVVIIGGAAGKTDSTNFLELNT. 462
48 0.000e+00UniRef50_A0A1F5URD1 Pyruvate kinase n=1 Tax=Candidatus Firestonebacteria bacterium RIFOXYC2_FULL_39_67 TaxID=1817861 RepID=A0A1F5URD1_9BACT  ali  36  2...............INWNRVKIVATAGPASESYETLKKMITKGLDIVRINFSHGKYEEYKKTILLVRRIEKEIK-RPIGILADMPGPKLRVRGI--EKSIPVKEGSIVTIV----KGMPKADNEFNIAYPVILKVLKPGDKIFISDGKYIIKVVSKAKNT-VTCKVIDGGEIKKGAGLNFPEVDLPIPAITSEDFKHMTFACANGVDFIGLSFIKDASDLKKVRAHLKKIKAKPFLISKIERRAAIANLKEIVHSTDGVMVARGDLGVELPIEKVNILQKEIIKMCNALGKPVITATQMLESMIENPSPTRAEVSDVANAIFDGTDAIMLSGETAIGKYPIQAVEMMYKIGKTVEPKIDRSKNVDYL-----ATDDLSDIISKNVVRISEVYGVKDILVPTESGKTARMVSRYRPNARIIALASTERVQRQLVLPFGVYPCRIPKHANSS------VIFKLTDEFIKKSNLFKKGDKLIIAAGTLKLKGNSNFVKIMTV 469
49 0.000e+00UniRef50_A0A061S428 Pyruvate kinase (Fragment) n=2 Tax=Tetraselmis sp. GSL018 TaxID=582737 RepID=A0A061S428_9CHLO  ali  41  1.......................................................................................PEIRTAMLRGHEPILLEAGQSIVVYTEFEGYKTEEETVIGLSYAKLCQSVEAGNTILLADGSISIEVLAVVSPTVLRGRVNNTAKLGERKNCNLPGVRIDLPVLTQKDVNDLNFACKYHVDYVAASFVQSKDDVLFIRKILDDNGGEISIISKIENAEGMRNLDEILDCTDGIMVARGDLGMEIPSHKVPFAQKMMITKCNLRGKMVVTATQMLESMVLNPRPTRAEMTDVANAVLDGTDCVMLSGETANGDFPDIAVSTMAAICQNAEQMVDITKRYNYLHDHTPKPVSDAEAVASAAVQCAQDMGAKAVIVLTTTGRSAGLVAKYKPTMPVFVCSKYPEVAKQSRTLYGTHGVLSDTVLTK-----VHSIIPHVQAYAKMLGEIKNGDQVVFISRRP.............. 404
50 0.000e+00UniRef50_A0A0M9E236 Pyruvate kinase n=4 Tax=Proteobacteria TaxID=1224 RepID=A0A0M9E236_9DELT  ali  37  8.....................KIICTLGPSCHTQEQIKRLADIGMDCTRINFSHGSHEDKVKIFENVREADDRL-----AILCDIQGPKIRIGTV-KDSGVHLKQGKKIIVTTDPI---EGDQERISISYEKLPQEAKSGDLIYINDGLVSLKILDIEKNN-LNCEIITGGFISTKKGVNLPSTKISLTVPTEKDVEDLKLIAKLDPEYIAVSFVNDDQDILTIRKILEDAGNNIKLIAKIERPFALENFDKILAVSDGIMIARGDLGVEIAAEDVQPVQKSLIRKCNIAGKPVIVATQMLESMTNAPTPTRAEVSDVYNAIEDGADAVMLSAETASGQFPDKAAAMMERIIRSAETHMKH-LNPEELDSEKRTHSELIGHLVFSACKDLSAHSSGKIICLTRSGYTSRMISKYRPFFPIFGITDTKKFSREMRINWGVEPVVIEELENAKTNID---RIKMAVEECYRRKFIGGDDKIIVTGNNFFNEQETNM...... 468
51 0.000e+00UniRef50_A0A290XHA6 Pyruvate kinase n=1 Tax=Luteimonas sp. 100111 TaxID=2006110 RepID=A0A290XHA6_9GAMM  ali  33  288..............PAHRRRTRILATLGPATDAPGVLDALINAGVNAVRLNFSHGDPESQRVRAEA-VRAAADRAGVEIGILADLPGPKIRIEKFAEGK-IQLQAGARFDLVADPDAPL-GTVHEVGVSYLGLPDDVEAGDVLLLDDGLMQLQVTAV-EGARIVTTVLNDGVLSNRKGLNKQGGGLSLGALTDHDRQLIKVAADIGVDFIAVSFCRNAADMEEARSIARSHGSDAALVSKIERTEAIDNLAEIIDASDVVMVARGDLGVEIGDAELPGLQKKIIRESLARNKVVITATQMLQSMVESPMPTRAEVLDVANSVIDGTDAVMLSAETAAGAYPVRAVEAMARICVGAERQFAQDTDFEKAQRNLERAD---QAIAMAAMFLSEHIGVAAIVAMTESGGTARYLSRFRGGVSIYAFSRHDGARRRMSLMRDVFPFNYDSRGQTPR-----EAARGSIRLLVEAGLLGEGKRVVFTSGEHMETGATNTLRLLQV 762
52 0.000e+00UniRef50_A0A142X737 Pyruvate kinase n=1 Tax=Planctomyces sp. SH-PL14 TaxID=1632864 RepID=A0A142X737_9PLAN  ali  33  14...............SRTSQTKIVATVGPASATVDKLAALIREGVDVFRINTAHGDREGHANYLALVREAEKK-AGQPVGVLVDLGGPKMRLGFLPGGA-LTCNQGDTVRFVRGEVTT---NPAELVCTYPTLIEELHVGDRVMLADGVVALQVARI-EANEVECTVLQGGTVRDKQGVNLPGVKLSVASLSDRDRATAEWAAGAEVDFLSLSFVRRAEDVLELRQLVHQAASEVQIVAKIEKPEALSNLEGIIAVADAVMVARGDLGVEVDIAEMAVIQKRIVKVCRALHKPVIIATQMLDSMHHSRLPTRAEATDVANAILDGADACMLSGETAVGEYPVESVQMMTRIALATEPLAREFDRAPKAVGRIAGITRVTEATAQGTVRLAEDLDAKLIVVATTSGRAALAVSQHRSRIPAIGVSPFPALLRRLCLYRGVIPV------PDAPTNDLLSLRDFVVKNAVETGMLKRGDRIVFLSWTGKGASRHNQISVHEV 486
53 0.000e+00UniRef50_A0A2D5N244 Pyruvate kinase n=7 Tax=Proteobacteria TaxID=1224 RepID=A0A2D5N244_9GAMM  ali  34  2.................LRRTKIIATIGPASSKYKILEGMVAAGMNLARINFSHGNKKEYIEIIKMLREISLKC-DSHIGIIADLQGPKIRIKSFQ--KNVIFLNNSKSFFLDSSLAESAGSEVGVGVDYENMSQDVSIGDSILLDDGRIKLRV-EKIEGTRINTFVECGGELSNHKGINLPGTGLSITAITKKDRQDILLAAELNIDFLAISFVKDKSDIEEVRRLYKLAGGQGRIIAKIERTQAYNNLDEVIEATDVVMVARGDLGTEIGFAELTGIQKEVIRKTRRRNKPVITATEMMQSMINSPLPTRAEVSDVSNAVMDGTDAVMLSAETAIGVNPVAVISSMSEVICGAEK--YNLPKGKSAYRIDNAFKTIDESIAMAAMYTANHYSVVAIIALTESGSTPLWMSRIRSEIPIFALTPHNFSGRRVTLYRGVYPLSLTINDRSLSDEFIFDLI-------LEKGFAQEGDSIILTRGSEDGSGGTNSMRVLKV 473
54 0.000e+00UniRef50_A0A1Y4D4K6 Pyruvate kinase n=2 Tax=Desulfovibrionaceae TaxID=194924 RepID=A0A1Y4D4K6_9DELT  ali  35  1.................MNKTKIVATLGPSSNSPDKIRALAKAGASIFRLNFSHGSAKDFVEIIKSIRDIERELR-IPLTIMQDLSGPKIRLGEIRED-SIHVQQGMKLLLGTTGHYTNE--LPYLPFDHEEVLDSLVAGDRLVLADGGLEFTVVERREDHLILLEAKNSGLVTSRKGLALPGKATRVRALTEKDKRDLMDGIRLGVDAVAMSYVQTADDVREAKELINQHSLRVPVCVKLERENAVHNLPAILAEADIVMVARGDLGVECPLPKLPSIQKHIIKACNNASKPVIVATQMLLSMVNSPSPTRAETTDVANAVLDGADCVMLSEETAMGHFPVETVAYMRRITNEAEAIMESRHALEE----PSEQRGIPSYLAYSACLLAQKARAQAIVIHSLSGASARKVSSCRPPQPIYALTTENSSVKYLNYSWGVTPVLVEEPETEPSH------LYRTENFILQNDAFKKGDCVVITAGQFSSARGTNLIKI... 472
55 0.000e+00UniRef50_P21599 Pyruvate kinase II n=4445 Tax=root TaxID=1 RepID=KPYK2_ECOLI  ali  36  4................RLRRTKIVTTLGPATDRDNNLEKVIAAGANVVRMNFSHGSPEDHKMRADKVREIAAKL-GRHVAILGDLQGPKIRVSTFKEGK-VFLNIGDKFLLDA-NLGKGEGDKEKVGIDYKGLPADVVPGDILLLDDGRVQLKVLEVQ-GMKVFTEVTVGGPLSNNKGINKLGGGLSAEALTEKDKADIKTAALIGVDYLAVSFPRCGEDLNYARRLARDAGCDAKIVAKVERAEAVDAMDDIILASDVVMVARGDLGVEIGDPELVGIQKALIRRARQLNRAVITATQMMESMITNPMPTRAEVMDVANAVLDGTDAVMLSAETAAGQYPSETVAAMARVCLGAEKI---PSINVSKHRLDVQFDNVEEAIAMSAMYAANHKGVTAIITMTESGRTALMTSRISSGLPIFAMSRHERTLNLTALYRGVTPVHFDS------ANDGVAAASEAVNLLRDKGYLMSGDLVIVTQGVMSTVGSTNTTRILTV 479
56 0.000e+00UniRef50_W0EP88 Pyruvate kinase n=14 Tax=Bacteroidia TaxID=200643 RepID=W0EP88_9BACT  ali  37  5....................TKIVATISDSRCDVDFIKQLYDNGMNVVRMNSAHLQEEGFRKIIDNVRAVSNK-----IAILMDTKGPEVRTTALAGDSNLQFSTGDLVRITGREGTLTG--NGYIGVNYPFFAQDLDEGSHILIDDGELEFVVRGK-ENGDLLCESLNNGELGARKSVNVPGVRINLPSLTERDIRNIHYAIKQDIDFIAHSFVRSKQDVLDIQAILDEYKSPIKIIAKIENQEGVDNIDEILEAAYGVMVARGDLGIEVPQEKIPGIQARLIKKCIQAKKPVIVATQMLHSMIKNPRPTRAEVTDIANAIYQHTDALMLSGETAYGKYPVEAVATMARVAEEAEQN---KLSESNIRVVSPDEPDVTSFLAKQAVKTFNKLGTKAIITDSYTGRTARYVAAYRGRYPVLAICYYERTIRLLALSYGVFPLYQERTRTSR------EYLFNGLNHLMEQHLIDRDDLIAYLGGGFGEGKGTTFLEINRI 467
57 0.000e+00UniRef50_C9MST6 Pyruvate kinase n=661 Tax=root TaxID=1 RepID=C9MST6_9BACT  ali  34  1.................MKQTKIVCSISDRRCDVDFLRKLFFAGMNVVRMNTAHATPDGIREIIRNTRAVS-----PHLALLIDTKGPEVRTTG--TDNPIHYKAGDMVKIFGRPDIDT--TKDIINVSYPDFTRDVKVGDHVLFDDGALDMLIVE-SAGPMLVAQVQNEGDLGSHKSVNVPGEHIELPALTEKDKRNILLAIDEDIDFIAHSFVRSAADVLEVQKILDEHNSDIKIISKIENQEGVDNIDEIIDASYGIMIARGDLGIEVPIELIPGIQRSIINKCILKKKPVIVATQMLHTMINNPRPTRAEVTDIANAIYSHTDALMLSGETASGKYPVEAVQTMARIAEAAEVDAHKRGHINVPMTNL---NDQREFLSRSAIEATEQLGVKGIVTDSETGLTARNLAAFRGPNPVLAICYKEKVQRWLNLSYGVIAIY------QQQHKSSQEMFTAALRMLRQKGYIDLEDNIAYLSGSFGGSGTT-FLEINKV 463
58 0.000e+00UniRef50_A0A2G6MDL0 Pyruvate kinase n=2 Tax=Desulfobulbus TaxID=893 RepID=A0A2G6MDL0_9DELT  ali  36  5..................NKTKIVCTIGPASRSPEVLEKLMAAGMDIARLNFSHGGFEQHKKDIQQIKAVAHKL-GKPVAIMADLPGPKIRIGDLA-EEEIELVNGQSLILTTLDVV---GTTEKIAVNLPNLHQVVAVGENIFLNDGFLQLEVKEIR-GRDIHCRVVVGGPLRSKKGLNIPDVDLGIDILTEKDKEIAAFALENGADALSLSFVEKAEDIVELRELANDLDHDPFIIAKIERSQAITNLDAILSQADGIMVARGDLGVEIPIARIPVVQKMIVRKANQLGKPVITATHMLESMIHNVIPTRAEATDVANAILDGTDCVMLSGESAVGKHPVESVTTLSDIAVEAEHLRSTQKSYSS--SALTPASCSLDIIAPSVEASVYRLSPAAVLVPTRSGTTARNIARHHLPVWVVGVSKKKKSCMDMVFTYGVIPVHEHDHPTNWR--------HWAKKMLEEHGL--HGKWVILTEG................ 452
59 0.000e+00UniRef50_X1JLH9 Uncharacterized protein (Fragment) n=1 Tax=marine sediment metagenome TaxID=412755 RepID=X1JLH9_9ZZZZ  ali  36  1..................................................................................VDLQGPKIRCGKVKGDN-IQLKGGEKYFLTTEPYL---GDENKLQILYKGFVKDMEPGVKVLLDDGKIELEVVRKEPD-EIECEIINGGIIRSNKGVNLPETTLSLDSFTPRDHNDLVFSLNHDIDWVSISFVRSAKDIEKVREVIEDYGSNIRVVAKIEKHEAIKNIDSIIGTSHGVMVARGDLGAEIPIEDVPKYQKMIINRCNLQGKPVIIATQMLESMVKNPRPTRAEANDVANAVYDGASAVMLSAETAIGKYPVESVRIMSRIINSTESIIDYKAKMMEKLKIGYK--SVTDSIALASCEIAKNLDAAAIITSTQSGHTAREISKNHPSTPVVAVSPVQRVVNQLKLSWGVYPILSKR------SKSIDEMIDNAVKLALENKFISKGDIVVITAGVLVDPGTTNMLKVHIV 406
60 0.000e+00UniRef50_R7F0R3 Pyruvate kinase n=2 Tax=Terrabacteria group TaxID=1783272 RepID=R7F0R3_9BACI  ali  35  1.................MKKTKIICSIGPATHPWEKFKGLVEAGMNVARINFSHAVLEEREAVENLVKRANEEL-GANIGVLYDTKGPDLRTCEFENDK-IDLVAGNTIRIVEEDVI---GNQERISLNYKGVLKELKVGSVILLDDGFYKLIVTSVEADG-VTCEIQNSGTIKSRRGVCIPGEKLNVPYISEKDREDIKYACDKDGDYLAISFVNSADDVNQVRELCKEFGKNMPIISKVETQYAMDNLDEIVEASDYIMVARGDLGIETGVENLPLYQQMMIDKCHANGKGVIMATQMMYSMKTNIRPTNAEVTDVANAVLAGCDAIMTSDETTIGQYPVETIQTMTSICENVERITKYN-----LSEYKLRGTEIHNTIAKCAVDATIELPVKAVVVSTLTGKTALDISSLRPNSFIIATVTDPKVARSLALKWGVYPKLVP------FFDNTDDIVNEGIKAAKEAMHLQENDIVVVVGGFPKEA-HTNFMKIEEI 466
61 0.000e+00UniRef50_A0A177Q0A2 Pyruvate kinase n=2 Tax=unclassified Bacteria (miscellaneous) TaxID=49928 RepID=A0A177Q0A2_9BACT  ali  33  3..................RRAKIVCTLGPASAAPAVIAQMIDAGMDVARLNTSHGSLDDHIATVKRVREVAA-VAGKHIGVLMDLSGPKLRTGPRPHG-PLSLIEGHTVEVTTDIAAAGG---DRVFVPYAGLVDEVGPGERVLLDDGNIALRVESREGSDSLRCRIEHGGELQANKGIAFPDSELALGALTERDERAIAAGVAAGVDFFALSFVSNVADLERARHLISQRGADTPIIAKIERRVALNSLDELLIEADGAMVARGDLGVELPPEEVPWQQRRIIDASARALIPVITATQMLESMIQSPRPTRAESSDVANAVWDLSDALMLSGETAVGRYPVETVRMMDRIISRAEAAPDAFRG----ISATPLNDDHSYVIALAAKRIVEDANMRAVVCFTRSGHTATLMSKVHPEAPIFAVSPTEAICRRLSLARSVIPLH------GALVETSEEMLQMVDELLVRDGHLAVGDEVVVVASLPVRAGATNFLKLHRI 471
62 0.000e+00UniRef50_A0A0C2V1E2 Pyruvate kinase n=15 Tax=root TaxID=1 RepID=A0A0C2V1E2_9PROT  ali  32  2.................MRKTKIVITLGPSTSSFEIVKTLISKGVNVFRLNFSHGDYETYAENIKTIRQASKEL-NKEVAILQDISGPKVRIGKIKG--VLKLKKGDTLKLAKEE---NEEDDWTLSLSYPLIIDMVNIGEEVFFADGTIQTVVVDK-DDHHLALKLLNDGELTSKKGVNFPKTKLSISSITKKDEQDLAFGATHDIDIVALSFVQSKEDILKAKRIMKEHHFDPFIVAKIETGEAIENLKEILEVSDGVMVARGDLGAEFGVTKLPRIQKHIISIANEMNKPSIIATQMLTTMINSPFPTRAEVSDIANAVYDGSDAVMLSDETTIGKFPLQAVDVLHDTIKDVEKDYPYFKEFKTL--------DKSDAVSKSAVELAKNLDKEALVPFTTSGMSAQTLSKYRPKQSIYAVSHSLKTHRRLSLVWGVHPLFVMEE-----IKNPTRLLYNFVQKILAEERATMDTRFIVTIGSTTGEGSTNLIRL... 462
63 0.000e+00UniRef50_A0A1J4UNT5 Pyruvate kinase n=1 Tax=Candidatus Micrarchaeota archaeon CG1_02_51_15 TaxID=1805249 RepID=A0A1J4UNT5_9ARCH  ali  37  4..................RKTRIVCTLGPGCD--GQLDKLIAAGMNAARFNMSHGSLESHSKRLGLLRHACKK-TSANIALIADIKGPKIRTGTFRN-SSVELVEGERVVLKAGNAEGNSGGSKIIFVNYPNLLETLAHHRIVYFADGLLEVKV-EHADKNDAIARVITGGKLGDCKGVNIPGAHLVQSTFGEKDWQDVHWAVKNNFDYIAQSFVRSAKDVQKLRQLLEKGEKHTHIIAKIEDHVGLEKIDEIIAKADAVMVARGDLGVQIPVEDVPRAQKSIIARCNAAGKPVITATQMLESMTNSPFPTRAEVSDVANAILDGSDAVMLSGETAAGKYALHTVETMARIASHAEQHMTCEK--KHLSCTGKGPKQVACAVAEAACRAAERIDATAIAAFTETGGTAFLISAFRPCTKIIAVTPLEKTARWLALCRGTEVVHVKTY------KHVSETTNLVSKTLREHNCVPKGSQVVVVAGTP---GNTRFMRIVDV 473
64 0.000e+00UniRef50_A0A061R0Z1 Pyruvate kinase n=1 Tax=Tetraselmis sp. GSL018 TaxID=582737 RepID=A0A061R0Z1_9CHLO  ali  43  80...................RCSVIATVGPNT----PIGECVEAGMRIMRLNCSHGDQSFFESKVACLREYLDNRPNRNCAVAFDLKGPEIRTGRLFDDRQVSLSAGEHVVLTTDRALXETGANHVIPVDYPGIAGVVGVGSEVYVDDGLIRLEVVA-MTDTALECRAVNSGVVAERKGVNLPGAILDLPAVSSKDVEDIKLAAKVGADFIFASFVRKGEHVRAVREILRGLGRPIKIISKIENQEGLDNFGDILEASDGIMVARGDLGIEIPAHKVVTAQKQLINACNAAGKPVVCATQMLESMVSNPRATRAEVSDVANAVLDGADCVMLSGETAKGRYPVEAILTMGQICREADNLVEYDQVHAR-RAPLMFPHSMHESICAAAVRCAMDEKAALIVVFTTSGLAPQFVSKYRPPMPVLAATADPVIARQSYMLRGITPLLLEDMAHGHLLCNMDEVLEGAVEYAKRIGICEPGD....................... 557
65 0.000e+00UniRef50_Q07637 Pyruvate kinase n=913 Tax=root TaxID=1 RepID=KPYK_LACLA  ali  36  3..................KRVKIVSTLGPAVESAKNIAALIEEGANVFRFNFSHGDHPEQGARMATVHRA-EEIAGHKVGFLLDTKGPEMRTELFADGADISVVTGDKFRVAT--KQGLKSTPELIALNVAGIFDDVEIGQTILIDDGKLGLSLTGKDAATEFEVEAQNDGVIGKQKGVNIPNTKIPFPALAERDDADIRFGLSQGINFIAISFVRTANDVKEVRRICEETGNHVQLLAKIENQQGIENLDEIIEAADGIMIARGDMGIEVPFEMVPVYQKLIISKVNKAGKIVVTATNMLESMTYNPRATRSEISDVFNAVIDGTDATMLSGESANGKYPRESVRTMATVNKNAQTML---KEYGRLHPERYDKSTVTEVVAASVKNAAEAMDIKLIVALTESGNTARLISKHRPNADILAITFDEKVERGLMINWGVIPTMTEKPSS------TDDMFEVAEKVALASGLVESGDNIIIVAGVPVGTGRTNTMRIRTV 501
66 0.000e+00UniRef50_A0A0G0QUA9 Pyruvate kinase n=4 Tax=Bacteria candidate phyla TaxID=1783234 RepID=A0A0G0QUA9_9BACT  ali  36  12..................KRTKIIATIGPVSEKKTVLAQMLKEGMDVARLNFSHGDFSWHKKAIRNIREVSWK-TKRPIGIMVDLQGPRIRT---IGNREERIRKGETVMVAGRNSVKKSGKQKIIFLDLPEMTKLVKVGNEILIEDGLIKLSVFKK-DKKRLYCRAENDGVIKMRKGVNIPGISAKLGALTSQDKEVLDFALSQDADFIAMSFVRNAKEIKNLQDLIRKKKKIPQIVAKIERREAVKNFNEILAVSDAIMVARGDLGIEMPQEELPILQKEMVAKSLRAGKPAIVATQMLDSMIRNPRPTRAEVTDVSNAVIDHADAVMLSGETASGKYPIEAVKMMRKIIEKTEESPFDDLEHGFL---GDEKMSVSSAIAQSAHELVKDSGAKAIVAASVSGYTARIVARHRPEERIFVMTNREKTHNQLTLVWGAESFVLPDCR------DLDELLDKSIATLKKNKLIKKKDKIVIVAGRPMKKEHMSLVKVEEI 486
67 0.000e+00UniRef50_H3BR70 Pyruvate kinase n=11 Tax=Bilateria TaxID=33213 RepID=H3BR70_HUMAN  ali  53  41...............................................................................................................................................................................KKGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMVFASFIRKASDVHEVRKVLGEKGKNIKIISKIENHEGVRRFDEILEASDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNRAGKPVICATQMLESMIKKPRPTRAEGSDVANAVLDGADCIMLSGETAKGDYPLEAVRMQHLIAREAEAAMFHRKLFEELVRASSHSTDLMEAMAMGSVEASYKCLAAALIVLTESGRSAHQVARYRPRAPIIAVTRNPQTARQAHLYRGIFPVLCKDPVQEAWAEDVDLRVNFAMNVGKARGFFKKGDVVIVLTGWRPGSGFTNTMRVVPV 365
68 0.000e+00UniRef50_J4KU04 Pyruvate kinase n=454 Tax=root TaxID=1 RepID=J4KU04_9PROT  ali  35  2.................VKKTKIVATLGPASDDEETMERMVKAGVNVFRLNFSHGTHEYHKSNIDKIRNIEKRLNVR-IGILQDICGPKIRIGAL--EAPFELKTGDRLDVYAKNITGAKPGHYTACINQPQILPLLKEGEHIYLYDGSIRAKIVE-AEEEMVKAQIQNDGVLNSNKGVNFPNTALGIEIITQKDKEDMKFGAKEGVNFVAISFVQNANDVIKAKNILKELGSRASVLSKIEKFDAVENIDEIIKQSDGVMVARGDLGIEVPFYRVPTIQKLIIKKANAASKPVITATQMMLSMAEHETATRAEISDVANAVLDGTDAVMLSEESAIGKNPVAVVEAMSKTIVQTQGIYPYNKFDEF------EFFDETDMVASSAASLAVRIKADAFLAITGSGKSAIKLARNRTNIDIIAIAHDEQTAHSLTLAWGVTPALVIEKTRLNI------LLANVVKEAFDAGFVKHDKTYLITAGYPTGVGSTNLIRILR. 470
69 0.000e+00UniRef50_A0A142YAT9 Pyruvate kinase n=3 Tax=Planctomycetales TaxID=112 RepID=A0A142YAT9_9PLAN  ali  35  13...................RTKIVATVGPASRDPAMLRRLVEAGVDVFRLNFSHGSHEEHSRTFQAIQDINREM-GRQVAVLQDLCGPKIRLGTIAGDVAA-CDLDAEFVLTSNPI--SPDDPRELTCTYQELADDLEIGQTVLFADGTVGMVVLEKRPG-WVRMKVTLPGRIRSNQGINVPGAALSVSALTPKDLADLEWTANHAVSYVGLSFVRHAADVTRLRAELQTRGSRARIIAKIEKPQAVANLESIVAEADGVMVARGDLGVEIDVAKVPAVQKRIIEICHRARVPVITATQMLNSMESSSRPTRAEASDVFNAVLDGSDAVMLSGETAIGMYPVDAVTTMSQIAYEAENLVFSRSHSGRTVARAGQVLPITEAVVEAASQVAATLRARLMVVATHSGRTALALSKQRAATPTLALTDDQEVALAMALYWGVTALHIPEIF------DTGQVLAFADEWCRQHDLIDTGDRLVVVRGVIPDNPNHNAILVHEV 501
70 0.000e+00UniRef50_Q8P5Z6 Pyruvate kinase n=313 Tax=Bacteria TaxID=2 RepID=Q8P5Z6_XANCP  ali  34  22..............KERQRRTKILATLGPATDPPGVLDALFKAGVNVVRLNFSHGDPSGQAKRAAEV-RAAAVRVGAEVGILADLPGPKIRIERFAGGK-IKLTMGDRFDLVAD-INAPAGDQHQVGVSYLGLPQDVTAGDVLLLDDGLVQLQVTDVQ-GARIVTTVLNDGVLSDRKGLNKQGGGLSLGALTERDKELIGIVAKIGVDFIAVSFCRNAQDMHDARQIAQQHGCDAQLVSKIERTEAIENLVEIVEASDVVMVARGDLGVEIGDAELPGLQKKIIRESLAQNKVVITATQMLQSMVESPIPTRAEVLDVANAVIDGTDAVMLSAETAAGAYPVRAVEAMARICLGAEHQFEFDTDFEAAQRNLQRAD---QAIAMATMFLSEHIGLGGVVALTESGGTPRYLSRFRSNMPIYAFTRHDGARRQMAMMRGVFPIGFDSRGLTPR-----EAARAAIRLLVENERMGPGDRVVFTSGEHMETGATNTLRLLEV 496
71 0.000e+00UniRef50_A0A1W9SU59 Pyruvate kinase n=2 Tax=unclassified Bacteroidetes (miscellaneous) TaxID=37452 RepID=A0A1W9SU59_9BACT  ali  37  3.................LKQTKIVATISDKKCDVPFLKQLFEAGMNVVRLNTAHQTTDDALKVIKNIRLVSER-----IAILVDTKGPEVRTTE--ADNKIIIKEGETIVFSGD--CSKKSTRSCICTSYDGFVKDVPVGGKILIDDGELEFTVVEKNE-TELICRIENDGELGSRKSINVPCVSFPLPSLSEKDIRFINFAVDQDVDFIAHSFVRSKEDLFAVQGVLDKRKSNIKIISKIENREGVDNIDEILDNCYGIMVARGDLGIEIPYEEIPGIQKYLEHKCMNRRKPVIVATQMLHTMTENPRPTRAEVSDVANAIYDGTDAIMLSGETAYGEYPVEAVETMTRIAQTVEK----EKQVYKAPSDEALHNKVSVFLAKSAVYASVQLPVKAMVADSMSGRTIRNLAAFRGQLPILAFCYNKTLMRELSLSYGVKTYYISR------RKSTDEFYHILTSVLLNEGKIQPDDLLVVIAGNFGAGHGASFIEIST. 464
72 0.000e+00UniRef50_M5BJC3 Pyruvate kinase n=8 Tax=cellular organisms TaxID=131567 RepID=M5BJC3_THACB  ali  67  42.SRLEWLSTLSAGPEPFLRKTSIIATIGPKVNNVDMLGQLRKAGMNVVRMNFSHGSYEYHQSVIDNVRKLVEQDPDRPLAIALDTKGPEIRTGVMRPGDDIKIAAGHEFIITVDPQYAEACDEKRLYMDYANLPAVTAPGKLIYVDDGILSLLVLSI-DGKDVHVRAVNNGTLSSRKGVNLPKTPVDLPALSEKDKKDLQFGVKNGVDMVFASFIRRAQDVIDIREVLGPDGAAIKIIVKIENEQGVENFDEILRETDGVMVARGDLGIEIPASQVFIAQKMMIAKCNMAGKPVICATQMLESMTYNPRPTRAEVSDVANAVLDGADCVMLSGETAKGSYPIQSGR-LNTIIR................................................................................................................................................... 399
73 0.000e+00UniRef50_A0A2E3ZWM9 Pyruvate kinase n=8 Tax=Bacteria TaxID=2 RepID=A0A2E3ZWM9_9BACT  ali  30  1.................MQKTKIICTIGPSSDHPHIISKLIQSGMNVARLNMAHSSHSHIESVVKTIRTESKRL-NCYVGIMMDLSGPKIRLDSGITGNEITIEKDHIYQLGFSKM-------NDIPINIDLTFNHVSTNAYVKIDDGKLSFKII-KSDKKFLRVKAENDCVIKNNKGVNFPGVELDIPSLTHKDEKDILKAIDLDIDWIALSFVRSSADINSIYKILNNSNVKIPIIAKIEKPEAIENLDSIIEEFQGILIARGDLGVELPLSKLPVLQKNIIEKCRKLKKPVIVATQMLESMIDSNTPTRAEINDVANAVFEESDAVMLSGETAVGEFPIETVKIMKKIISDVENNNVNNNLDKY---EIKLDNDTRSAIGDSVKTISKHMHIDGIVVMTESGSTARVVGHFRPSVNIFAFTPHSNICRQMTLLWGVTPIFMSECLT------TDDMLINAEKILLKNEYMNKGDTFILTAGIPIGSGATNMLKIQKI 468
74 0.000e+00UniRef50_A0A2A4XAI2 Pyruvate kinase n=2 Tax=Gammaproteobacteria TaxID=1236 RepID=A0A2A4XAI2_9GAMM  ali  35  47.................WRRTKIIATLGPASDSTEMINKLLEAGVNVVRLNMSHGDHESHRQLFSRVRSAAKQ-QDKNIAILMDLCGPKIRVGKFEEGA-ISLAVGQQVIVTCRNVL---GSDGLIPSQYRKLHKDVKKGERVLLDDGNLELCVQSI-KGTEVTCRVVHGGLLKDHKGMNLPDSDLSTPAFTDKDKKDALLAMELEADFVALSFVRHAGDITRLTRFMARHGEAIPIISKIERPEAVENIDEILVESYGIMVARGDLGIELPAEQVPMIQRDLIKRARLAYVPVIVATQMLESMITHSRPTRAEVGDVASAAHSSADAVMLSGETASGAYPVEAVETMVKVVREIERHQWRDGQYGSQVFANRRLSDFSEAVAHAALGLARDLKLQAIIVPTMSGTTAHVLAAHRTTAPMVGICSQEVICRRLSLHWGVIPVYLNTPDHQDWR-DICHRIESQVE------LAKPGHTVLVVAGFSADPRF......... 509
75 0.000e+00UniRef50_A0A2M7P6K8 Pyruvate kinase n=3 Tax=unclassified Deltaproteobacteria (miscellaneous) TaxID=122706 RepID=A0A2M7P6K8_9DELT  ali  35  1.................MRKTKIVATLGPATESREMIEKFIILGVNVFRLNFSHGDHESHRTLIRHIRAIAGRL-DMPVAILQDIAGPKIRVGTIAG--IMPLETGDRLTIYPD---RTKGGELEITISHPEILRTLAPGAAIYFADGAIRAEVRARV-GEAVVVEILVGGKLTSRKGVNVPLADLQIDLVTEKDKADIAFGVAEDVDYIALSFVRNSADITRVRKLVAGFGGDVPLVAKIELAAALDHLEEITAAADGVMVARGDLGVELGVHLVPVVQKRIIAAANRHGIPVITATQMLSSMLVSPFPTRAEVSDIANAVLDGTDAVMLSDETAVGDYPEEAIKVLGQTIAATETIYPWD-------RQVPRLADSREAIAAAATQLASNSGADGIVCFTHSGLAVEKIAQHRPATRLIGVTSNPRTYRQLALVWGVEPFFIE-----ISHANSDKAISLFVKHARLAGFIRETATYIVIIGHHSNTGTTNQVQIM.. 463
76 0.000e+00UniRef50_A0A2H0LGU3 Pyruvate kinase n=5 Tax=Bacteria TaxID=2 RepID=A0A2H0LGU3_9BACT  ali  32  4..........QTPAPAAWQRTKIICTLGPANEADLVLAGMIRAGMDVARINTAHGTPEGHAKRIAQVRRIAAEV-GRPVAILVDLPGPKLRLGPLPGG-SLTLKAGEQITLSVEPA------GHAIPVAYARLNEEVRPGEQIFLSDGEVALTVQRV-EGVRIVCRVENGGAIRSNSGMNLPTSELSVTLPTEEDTRNLKFAIEQKAEWVGVSFVQSLEDLQRVRALLPQKQA-PLLMAKIERRQAVINLKELLGGADGVMVARGDLGVEIDLAEVPLTQKRIVHSANAKARPAVIATQMLDSMVASPRPTRAEVTDVANAILDGADAVMLSDETAIGSYPVGAVEVLHRVIRIVEGEYPYGGAFTRFASGQMASRS-EESISFVASRLSFELGAKAILLPTADLRSAARIAQYRPKAPIIAITDSEFLCGQLSLLWGVVPHLGNP-------EKIDECVAHAQEWLTARGWAKAGDPIVLLKTSRPAQGFSDTLQVV.. 473
77 0.000e+00UniRef50_A0A1G1I1T3 Pyruvate kinase n=1 Tax=Nitrospirae bacterium RIFCSPHIGHO2_01_FULL_66_17 TaxID=1801712 RepID=A0A1G1I1T3_9BACT  ali  34  1.................MRRTKIVCTIGPASDDPAILKAMIEAGMDVARINFSHGTSQEHVARVARIRALAGEL-GRTVAILGDLAGPKLRTGNMTKE-SVLLKAGDPFTLTSEPI---DGDWRSTSVSFPGLEHAVKAGETILLNDGAIDLVV-ETVGAGLVRTRVRVGGFLGPHKGVNIPGRSLAIEALTAKDRDDIAFAIEHDLDWLALSFVRGADDVRTAKEWIERCGGRIPLIAKIEKREATEALDAIIGESDGVMVARGDLGVELALEEVPFLQKTIIAHALAREVPVITATHMLESMVSQPRPTRAEATDVATAVLDGTDAIMLSEETARGKYPVEAVRIMARIAERAERALDHGRFLNPGRAEAGISSAVARAACALAAEV----GVSAILVPTRGGSTPLQIATRRPVQPIVALAHDPRVRRRLALTWGTVALSGPDARSG------DEMIQRCVEAARAERLV........................... 440
78 0.000e+00UniRef50_A0A2M8DHL9 Pyruvate kinase n=1 Tax=Nitrospirae bacterium CG_4_9_14_0_8_um_filter_70_14 TaxID=1974059 RepID=A0A2M8DHL9_9BACT  ali  35  7...................KTKIVATLGPASRSATTLQRLLRAGVAVCRINLSHGTEAEHRDTVTMIRRVAEEL-GRPVAILMDLPGPKIRIGQLV-EPTITLRRGQALLLHVG---RRAGDGDHLYTPCAPLLRALKRGHHLYLADGTIQMQV-EMADGVTARCRVTVGGVLRPGKGISAPGVDLNMATITARDRALVRLAVDCGADMVSVSFVRAAADILQVQRLLRRAGSRALVIAKIERGEAVEAIDSILAAADGMMVARGDLGVETPIAGVPMLQKRLIAAANQAGKPVITATQMLDSMVANPRPTRAEVADIANAILDGTDAVMLSEETAVGHYPVEAVRTMAAVAEQTEASMGNDLPHRRLSDLAEA--TVTEAISRSVAQAAGLLAVRAVLAPTHSGQTARSIARERPGAWIYSFSTDPQVANALMLSYGVWPFHRGESAIDP---------NELIPPLLAARLLARGDRVILTWGRAAGSGETYAMRVERV 471
79 0.000e+00UniRef50_B3M214 Pyruvate kinase n=2 Tax=Sophophora TaxID=32341 RepID=B3M214_DROAN  ali  44  1............................................MRVVRLNFSHGSHELHCRVIQAARKAIEMYQQETVAIALDTSGPEIRTGQLSDGSPVRLKRGDKIILTTNKSVENQCTKEKIYVDYARLPVDVQVGKRIFIDDGLIGLHV-DKTSNEELFCTVLNDGKLGSRKGVNLPGSEVDLPAVTERDKRDLKFGVEQKVDMIFASFIRDANAVAEIRQALGPGGEGIKIICKIESQEGVKNIDGIIKASDGIMVARGDMGIELFSEDVPLAQKAIIAKCNKAGKPVICATQMLESMVSNPRPTRAEASDVANAIFDGADAVMLSSETAKGKYPVDAVRSMVRICAKSEAALWYESMQDDLKNVIRSTADQISAVTTAIAEAAMVSQAKVIVVACPCAMVGQMISQMRPMCPIVMLTGSHTEGSTSMIYRGVYPLLIEEMALGCM--DFRRIVRTGLNIMARMEILEAGTTVVLV.................. 446
80 0.000e+00UniRef50_A0A2M8DR84 Pyruvate kinase n=3 Tax=Parcubacteria group TaxID=1794811 RepID=A0A2M8DR84_9BACT  ali  33  5................NMINTKIVATLGPASKDLKTVRQLIKGGMDVARLNFSHGTYKDHRDLILILRKAA-KLEKKTIAIMQDLQGPRIRVG-IVAEEGIDLVRNKIVTLIFG--AKESTSKDIIPIDLPVVPE-LEIGSSILIHDGIIDLKV-EAVKGQDVKCRVLRGGIVFTHKGVNIPYTKINAPVITDKDRADLKFGMQQGIDWVAISFVGQATDVKKLRKLITDKTANIKIMSKIERPEAVNNIDKIINVSDGIMIARGDLGVEVSPQRVPIIQKDIIQRCMAVSKPVLVATQMLDSMIKSQVPTRAEVSDVANAVIDHTDAVMLSGETAFGLYPVESIQMMNKIIVETEMSPFDDRVD---LLYPPKKDSHYRAVADTIFDLVRDSNAKAIVVLSRSGFSVQLVASQRPHTKIIALVADDKIRNQLNMVWGVQAYKI------AVKKNLDELISQAISLVIKQKIVRKGQNVVFVSGQPVGSQHANMVEVYKI 476
81 0.000e+00UniRef50_A0A2E4WHI4 Pyruvate kinase n=17 Tax=FCB group TaxID=1783270 RepID=A0A2E4WHI4_9BACT  ali  32  10...............NNCTNTKIIATIGPSCDKKNILEEMISSGVNIFRLNMSHGD-ESSKKHLYNLVKSLKLDDGSRPTILTDLAGPKIRVTGVRNG--FKLSEGQSVLITNKANF----DKDEIQVTNGIEFNNLRKGAKILINDGKVQLEATQIVSTNSIRCKTLIGGEIKERKGVNFPGVSIDTPSLTQEDIADLKIALEEGADWIALSFVRSEKDILAIHKIMDEIGNRIPIMAKIEKWEALENLSAIANVFDGIMVARGDLGVEIPAEQVPLAQKRIINIAAVLGKPVVIATQLLESMLDSKTPTRAEVSDIANAIYDSADALMVTGETAIGKYPIDVIKTLKLVIIEVEKSVNSSR-----SSLPEEVNKTADAISHAVCQIAKDLDIDLIMTMTHSGSTARMISRYRPKGKVFALTPFNLIMRQLRIIWGVIPIKVDNY------NNIDEIPRLCINVLNGLGQIKKGDKFVITGGVPMGVGTTNYLSVLT. 476
82 0.000e+00UniRef50_A0A2E6F6C8 Pyruvate kinase n=2 Tax=Euryarchaeota archaeon TaxID=2026739 RepID=A0A2E6F6C8_9EURY  ali  36  6.............SHQNMRRTRIIGTIGPASDNEGTLEALVDAGLNIARLNYSHGDLEQKTELIQKLRKVEFKF-GRPLGILADLPGPKLRLGSFS--KSIKLSKNDIVNLHCGNEKNNDSNTYNIPVSYGGLSEDLNDGDAILIADGTVRLNVEKSKKDGLVNCKVIEPGVISSRKGVNVPGTLVSLPSVGEKDLFSIKHALENDVDFIAVSYVRNAKDLQPAVEAIKNAEKYTPIIAKIEHPAAIENLDEILDLCNGIMVARGDLGVEIPYEEVPLVQEKIIAKTLERGLPVIVATQVLESMINSPVPTRAEVTDIANSIRQGTSALMLSGETASGKYPIEAVQTMSKVCAHVEQGLETMSSSPALAKYRA-----TRAVAHAGVTLSEEENISRLLVASQNGNAARLVSAYRPKCPITVFTNKIETMRKNTILWGVESIMVEEEERSRS------TILNAIKILFDDGKIQPNDVLVSVSGSPKASGPTNTVRIFK. 490
83 0.000e+00UniRef50_D2VFN7 Pyruvate kinase n=1 Tax=Naegleria gruberi TaxID=5762 RepID=D2VFN7_NAEGR  ali  33  8..................RRTKILCTIGPSSSDKSIIMQMMMEGMNAARLNFSHGEHNVHLETIQKIREAQKELGGIPFAIVQDLQGPKIRIGKL--GKSFMIVEGEEIVITTDKSVIASGEDNKVSTSYPNLVRDCRPGSKLMIDDGYLEVHVVSKNEETEMVCKVVTGGMLSQRKGINMVGATISAPALTEKDIADLEFGMKCGINYVCLSFVRFAQDIIDAKNLMMKAGKTIPIIAKIERIEAIRNIDAILKEADGLMVARGDLMIETNFHELPIFQKELIEKSSKAGKIDITATQMLQSMVESKIPTRAEVTDVSNACFDGTDVVMLSNESAMGKYPVLSVKTMHLIVRTADSHKFGRLDSHENDFNSNATDSIENASCMAASTIANKHGVKLICCITNSGKTAVSISQYRPNVPIIALTDQEFTFNRLTLGWGITPVLIHNTDYITGPHSVEEL---CCKYLVEKSFAQPGDLVVLVIGAETVNHMAHTVRLMK. 496
84 0.000e+00UniRef50_A0A2H6GJN4 Pyruvate kinase n=3 Tax=unclassified Bacteria (miscellaneous) TaxID=49928 RepID=A0A2H6GJN4_9BACT  ali  34  1.................MRRTRIVCTIGPAARSSRMLEKLVGAGMDVARLNMAHGSREEHLAVITRLRKLSRK-KNRPVGILLDLAGVKLRISEV-NGSGVVLEKGAQVLLRQG---RRPTTSETLFVPYAGLTKNLKEGHRILIDDGRVELLVTG-REGNAIRARVREGGTLTSHKGLNFPDTDISTRSFTSKDRDDLAFGIRHGVDAFGVSFVSTAKDVMVVKKALKKAGYEAPLIAKIERPAAVKNIDEILDVSDGIMVARGDLGVEVSAAAVPIIQKDLILRAARKNRFVITATQMLESMIHSSVPTRAEAADVANAVLDGSDAVMLSAESSVGMYPIKAVQTMDLIVREAEGNSYRTDLPVPAPVSGGRPGHGGVATAEATARAAREVGARCIVAFTSSGYTAGLLSRFRPAVPIIAFTSNRKAVDRMKFAWGVVPLFME------HLDSTDAMIAEVEKALIKGRHARRGDTVVITASLPMAQGKTKFLKVHKI 479
85 0.000e+00UniRef50_A0A265QPI7 Pyruvate kinase n=347 Tax=root TaxID=1 RepID=A0A265QPI7_AGGAC  ali  36  4................RLRRTKIVCTMGPSTDRGNNLEKIIAAGANVVRMNFSHGSPEDHIARAEHVREIAKKL-GKTVAILGDLQGPKIRVSTFKDGK-IFLNIGDKFVLDA-ELPKGEGTQEVVGLDYKTLPQDVVPGDILLLDDGRVQLKVLST-EGAKVFTEVTVGGPLSNNKGINKLGGGLSANALTEKDKADIITAARIGVDYLAVSFPRSSADLNYARQLAQEAGLNAKIVAKVERAETVVDMDDIILASDIIMVARGDLGVEIGDPELVGVQKKLIRRSRKLNRVVITATQMMESMISNPMPTRAEVMDVANAVLDGTDAVMLSAETAAGQYPAETVAAMAKVCLGAEKMPSVNTSHH---RMDMEFDNPEETIAMSAMFAANHMGVTAIIAMTSSGRTPLLMSRISSGLPIFALSRNQNTLNLCALYRGVTPIYYDDVSR------TIEGAQKAINLLKEKGFLMSGDTVLLTQGAFANSGSTNTCRILTV 480
86 0.000e+00UniRef50_A0A1Q7DK08 Pyruvate kinase n=4 Tax=unclassified Actinobacteria TaxID=1752188 RepID=A0A1Q7DK08_9ACTN  ali  35  2...............SQVRRTRIVCTIGPSSSSPQVLRAMVLAGMDVARLNFSHGDADAHRQAAANVREAAEA-AGRPVALLGDLQGPKIRTGRV-EGTFQRLVRGRVVTLVGGGASAPKLEPNQIQVSHEELVQALRPGDRVLLDDGRIELAVRAVSDGQA-EASVVRGGLLGERKGVSVPGRTLPLPALTEKDLSDLKLAVELEVDYLALSFVRRPEDVIACQEHL---GGKIPVIAKLEKLEAIRQLSKILEVADAVMVARGDLGVELKLGDLPAVQKDVIDRANRAGVPVITATEMLESMVTSNRPTRAEASDVANAIWDGTDAVMLSQETSIGAHPVEAVRAMARICLAAQKHPDY----ERARQIWREPGEVGSAIAHAAAATAAEIHAKLIIAFTESGTTALRCSKARPPMPVVAASPHPEVLRRTALYSGVVPLLVSPGR------DTDQMISNATEAALVSGMVRPGDRVVVAGVPVGRPGQTNLLKVESV 485
87 0.000e+00UniRef50_A0A2V2GQT4 Pyruvate kinase n=2 Tax=Lentisphaerae TaxID=256845 RepID=A0A2V2GQT4_9BACT  ali  38  3.................MKYTKIVATINASTCTEELLRGLYKNGMDVVRLNTAHMEIADMDRIVALVRKVSDKL-----AIMVDTKGPNIRTCNL--DAPLALKIGDKLDLTGETVPQ----EKAVQVNYSKFTAEVPVGARIIFDDGAMELLVLGK-SGGLLHCEAKRDGELKNHKSVNVPGAELKMPALTRKDRDFIEYAVKNDLDFIAHSFVRSANDVLAVRSILDTGDSDIRIIAKIENRQGVDNLDEILKAADGVMVARGDLGIEIPLEEVPLIQKKLIRACMAAGKSVITATQMLQSMENSPLPTRAEINDVANAVYDGTDAVMLSGETAEGVYPVEAVSVMSRILEETEKSPDY--YFTRVREQISDSDENSAFLIHSAVEAAERLPVRAIVCNTASGLSARLCAAYRPRKPIFAFSYNPGVVRQLSLTYGVYA------GYNAFAEDVIDLTRQTCRTLIEEKRLAPDDKVAMLA................. 448
88 0.000e+00UniRef50_R5EEC4 Pyruvate kinase n=2 Tax=Gammaproteobacteria TaxID=1236 RepID=R5EEC4_9GAMM  ali  41  2........................................................................QETGKVFAVLLDTKGPEIRTCDLENGEDVSLVTGDKITLTSDSKFV--GNKTKVGVTYPNLAKDLKVGATVLLDDGLIGLKVIEINGD-DVVCEVQNNGDLGEHKGVNLPNTHISMPFLSEKDKGDLLFGIKRGVDFIAASFTRTKEDVLDIRNFLDANGGDIKIICKIENQEGLDNFEDILATADGIMVARGDMGVEIPAQDVIFAQKHIIKRCNQVGKPVITATQMLDSMIKNPRPTRAEAGDVTNAILDGTDAVMLSGESAKGKYPREAVRTMNTICERTDS--YCEENHGKVFPAVVSAKTVTDSACLAAVEAADALNVPVIVVATEHGNSARAIRKFNPKAEILALTPNVKAARQLCVTRGVMPKIVDRISS------TDEFFQLGKKLAVEMGLAKAGDKIVMVNGALVPSGITNTMSVQTI 419
89 0.000e+00UniRef50_A0A2D7S3M5 Pyruvate kinase n=7 Tax=Bacteria TaxID=2 RepID=A0A2D7S3M5_9FLAO  ali  33  3...............KNYRKTKILATIGPSSEKITKIEKLILNGVDAFRINCSHTKESQIKNYIENIRKVEKKLK-KPIGILIDLQGPKLRIGEIKNN--IPLKRGQKLLFINSKKSSK---SNEVPLPEEKVFKSIKVNHPIFIDDGKIKLKVLKVSKN-IIETKVLLEGILKSKKGINLPETVLKNSALTSKDKKNVKKGIELGVDWIALSFIQSPEDIKDLRKICKKN---VSIMAKIEKPTALNHINKITELADGLMIARGDLGVELPIQDVPSWQKRIIREARMQGKPVVVSTQMLESMITSKTPTRAEVSDVATAVFEGSDAVMLSAESAIGDNPELAVKMMDKIAHSVEKNPNYSSILSAQLEET--PDSTPDAIATAARSLASELNSPIIVCYTESGSTGIKVSRVRPKQMILTVTPIIRTARKLTLVWGVKCIVQKD------ANNLEQMIKMTKSYSKKEKIIKIGEKMVITAGLPLKKGTTNLIRVIKV 470
90 0.000e+00UniRef50_A0A1I7VJ66 Pyruvate kinase n=10 Tax=Opisthokonta TaxID=33154 RepID=A0A1I7VJ66_LOALO  ali  51  1.....................................................................................................MLENGNDVIVTSNDAFMSKCSTDIIYVDYKNIIKVIKKGSIIYIDDGLIMLLVQEI-DGESIYCKIENGGLLGSQKGVNLPGALVDFPAVSEQDHKDLRFAVEMDIDIIFASFIRNATEIREIRQILGEKGKQIKIIAKIENQQGVDNADEIIREADGIMVARGDLGIEIPPEKVFLVQKMLIAKCNIAGKPVICATQMLESMVYKPRPTRAEGSDIANAVLDGADCVMLSGETAKGKYPIEALLTMHQLCKQAEMAIFYTRTSEELIRLTPKPTDHAHTIAIAANSAVQSSEAVAVICITVSGRAATLVSRYRPPVPIYAVCTNYAIRRQLHLWRGIYPIYFEAI-NTDGREDLYDRIRYAVKCGKEQNVIHDGDPLVVVSGAKHG............ 385
91 0.000e+00UniRef50_Q1YVJ3 Pyruvate kinase n=12 Tax=Bacteria TaxID=2 RepID=Q1YVJ3_9GAMM  ali  34  1.................MRKTKIICTIGPATDSLEMLENLANAGMNVARLNMSHGTHESHRKVIDAIRVLNRKL-NHPIAVLLDTQGPEIRTGDLAND--LHLNDGDTISIVARGAEDVESSS--IHINYEDLITDVGIGDIITVDNGLINLEVLSK-EERVMQCKVLDGGLLKSKRHVNLPGIRVNLPAITDKDRRDIEFGMSLDVDFIALSFVRQAEDIHELRELLGDKADTIKVIAKLEDQEAITNMVEIIAAADGVMVARGDLGVEVPLEVLPRIQRRILRTCAEMGTRAIVATHMLESMIENPNPTRAEVTDVANAVYEEADAIMLSGETTVGKYPVKCVEILDRIARSTESSRGLRFTDNLAIEGDKQQ------IAQAAVNLAEAISAKAIIVPTKRGRMANRVTNCHPQESIIAFTNSGATRRQLVMNRNVLSYQID------FGKDSDSTLAAAAAIMIKRDEFSPEDRVVVISDTLAGDG-IEAIQIRQI 465
92 0.000e+00UniRef50_A0A2E7E1U6 Pyruvate kinase n=1 Tax=Legionellales bacterium TaxID=2026754 RepID=A0A2E7E1U6_9GAMM  ali  33  3..................KRTKIIATLGPSTDDPGVLSDLIASGVDVVRLNFSHGDVASHRRRVQNVR-MCAQSQNRVIGILADLQGPKIRIGAFQSG-SVMLTEGQAFRLDSR-CEKAQGDESGVFLDYSALADQVNIHQQLSLSDGKIILSVTACSPG-VVDTIVITGGELKDHQGINLVGGGLASGALTDKDRSDLSIACELCVDYIALSFVKDAQDILQAKALIQSSRSEAHVIAKIERLEALSHIESILNVSDGLMVARGDLAVEVGDAEVPAIQKQLIHQAKAAAKPVIVATQMMESMIHASTPTRAEVSDVANAVLEGADAVMLSAESATGAHPVGAVNAMVRVCLAAESHQPTRSKL----LMDKELSRTDEAVATAAIFTANRLDIQAIVALTESGRTALWMSSIQTKMPIYALSRHDRTLGQLALYRGVHPIYFDVMP-----LNVHVLGEQVIEALKAQGWLHVGHRVILTQGDHLGSGGSNTMKVLDV 472
93 0.000e+00UniRef50_UPI0003A730C5 pyruvate kinase n=1 Tax=Euryhalocaulis caribicus TaxID=1161401 RepID=UPI0003A730C5  ali  31  8..................RACKILATLGPASRSTKVIAELIQHGADAFRVNMSHGDHETHAETIARIRQAAESL-GAHVAILADLQGPKLRLGDLDGD--IEIRAMEKRTLTLGESAGG----EALPVPHPELFAALEAGDSVLFDDGAVAAKVVS-ADGESAELQFLNGGTLSANKGINLPGRALDIGALTDKDLEDLDFALDQEVDYIAVSFVQRAADVRQANERIR---GRAAVVSKIEKPSALDDLEDIIALSDAVMVARGDLGVELSLEDVPVAQRRIIRACRRSGKPVIVATQMLQSMIDSATPTRAEASDIATAVYLGADAVMLSAETAVGRHPLTAVAIMDRIIGAVEADPEYEHYLPPL--DMPDRSSQAQALSYAVRNACEAHGCDAIFAFTQSGASAAAVARERPHAPIFGVSPYAAAARRMALIWGVQPM------TRPAPDTFDAAIEQARALMREIDDVENG---LLVGGLPFGSGRTNVLHLL.. 466
94 0.000e+00UniRef50_Q7UF82 Pyruvate kinase n=17 Tax=PVC group TaxID=1783257 RepID=Q7UF82_RHOBA  ali  37  5..................RHTKIIATIGPATESPEKLAALIEAGVDVMRLNMAHGTPEWVGEIVARIRKVSKDIS-RHVAVMMDVKGPEIRTGAVED--AIELKAGDELVLFTEDCADQSAVESRVSVNYLGLPGAIDLDSTILVDSGLLHWHVLKK-DATTVRCRVITPGVLESRRHINLPGVQVNLPAITDKDRTDLAAGVKAGIDFVALSFVRQAEDVRTLRAFLDEHGSPARIISKIEDQAGVRNMKAIIRQSDAIMVARGDLGVEIDYHRLPLVQTDLIRACQEDGKPVIIATHLLESMIQSPVPTRAEVSDVSNAIREQADAVMLSGETTTGKYPLESVGVLQNIVASIEPTVSRQLNSKIVLREPKS------MMLRSACTLAQEMGDSGIVVFTRSGFLAYVLGALRPRVPIFAFTDVEHTFRHLMLPWGVEPFFME------FSEDHDQTITNALEVLKESGWCKPGVWLGVITNALADEKIIDTLQLRQV 475
95 0.000e+00UniRef50_A0A2E5TWS0 Pyruvate kinase n=2 Tax=PVC group TaxID=1783257 RepID=A0A2E5TWS0_9BACT  ali  35  5..................RQTRILATLGPATQSEEMIGALIDAGANLFRLNMSHAKSXWVHEVVVNIRAAAATRGCVP-GILMDLQGPAIRTGVL--DKPVDLKKNDRFDFTTNIKKQG---ERVVAVNYPSFLDDINEGATILIDNGLIRMKVLRKTADVA-ECEVEIGGKLGSRRHINLPGTKVNLPALTNKDKADIQVGLDLKVDYFALSFVREPADIDELKALIASDEHSPKVVAKIEDQHAVKRIKRIIRSADAIMVARGDLGVECPYEELPIIQRGIVRQCLKVGKPVIVATHMLESMINEPHPTRAEVTDVANAVFEQADAIMLSGETSVGKFPVMCVEVMDRIARRMEEEVGARFHKEASLENKR------EKLAKSAVTMADDLNADAMVVFTASGRMVRETAWMRPKHKILALCADERVAGEMSLYRGVEPVIIEGFCPDFPVLD-------AISTLKERGFLIIGNTVVVSSSTKAVEQISNSVQVHRV 467
96 0.000e+00UniRef50_T2KQJ8 Pyruvate kinase n=32 Tax=Bacteroidetes TaxID=976 RepID=T2KQJ8_9FLAO  ali  34  1.......................................MLDEGADVFRINFSHADYADVTERVKMIRELNEEF-GYNAAILGDLQGPKLRVGVMKGE--VFVNPGDEIIFATGERF--EGTKERVYMTYKQFPQDAKPGERVLLDDGKLIFEVVSSNNVDEVTAKVIQGGPLKSKKGVNLPNTNISQPALTEKDIEDAIFACSLQVDWMALSFVRHAEDLMQLQELIKEHSEKIPIIAKIEKPEAVENIDKIVAYCDGLMVARGDLGVEIPAEEVPLIQKQLVLCAKKARIPVIIATQMMETMIDSLTPTRAEVNDVANSVMDGADAVMLSGETSVGQYPIQVIKQMSNIIKSVEDSPLIK--VPQSPPHIRTKRYITKSICFHAANMANEINAQAISTLTNSGYTAFQISAWRPSAHILVFTSNRRILTQLNLLWGVKAFYYDKFVS------TDETIEDVNKLACDKGYLEEGNMLISLAAMPIEKGMVNTLRVSEI 450
97 0.000e+00UniRef50_A0A2D9CJD8 Pyruvate kinase n=1 Tax=Phycisphaerae bacterium TaxID=2026778 RepID=A0A2D9CJD8_9BACT  ali  31  49.............EPTRPAHAKIVATLGPASDSDDMLAKLIEAGVSIFRLNFSHGNLDEMAERLTKVRRAI-DNSGKCVGILGDLQGPKMRVGDMHEGGGIVVKPGDDIVF--KRGHGEASIENGLPTSFDELYEDVLPGQRVLINDGFIRMLAVDQIKGESLRCRVTIGGRITSKKGINLPESDLNMPAITEKDWACAKWAAENQLDYVALSFVRTPDEIKELKAKLDEWRPHIPVVAKIEKPQAVENLDEIIQATDAVMVARGDLGVEMDVAKVPVIQKYIVARCNTLGKPVIVATQMLETMIESITPTRAEASDVANAVLDGCDAVMLSGETAVGAHPRAVVETMQRIIRVTESRMDELALNQAPPTLKEYPFRSA-ALAKGVWNMAEELGAKAIAVWSEAGGMARYLSQNNFRVPIYAYTSSSLAARRMALYGGVHPIYTKPPETGRLRDWTD-MVEELIS---SEGITHDGDAVLLVAGKPLGA........... 534
98 0.000e+00UniRef50_A0A2D6BJM9 Pyruvate kinase n=1 Tax=Deltaproteobacteria bacterium TaxID=2026735 RepID=A0A2D6BJM9_9DELT  ali  36  1.................MPATRILATLGPASWDRASIDSLARAGVTAFRLNFSHGIHEVLARVIADVRAVEAEL-GWPLALLGDLAGPKMRTCDVAGGGSIMLGVGDEVVITAEDAETTPG---RIAVACPGLPAALDPGDKVLFDDGKLEVEVLESSRGEA-RGLVIFGGPLSSKKGVNLPGGRVDIPSITEKDEADLAFAIEHGVDWIALSFVQETRDVVDLKRRIAVAGARIPVIAKIERPLAVEDLDAILEVTDGIMVARGDLGVELGPETLPVVQKEMILSARRRSRLVITATQMLESMTHEPRPTRAEASDVANALFDGTDVVMLSGETAVGDHPVRVVETMRAICEDAEKSDLYHGKMASLLR--PDEGGVAHAAIRAACAAAEEVEARAIAVFTATGWTALAASAWRPRVPIYAITPEDRAWRRLALAWGVEPVRITGKAASP-----DALHRQGIEVLLETYRLMAGDIVVLLSGSVLDGHGANTVRILRV 471
99 0.000e+00UniRef50_A0A0G1LAU1 Pyruvate kinase n=5 Tax=unclassified Bacteria TaxID=2323 RepID=A0A0G1LAU1_9BACT  ali  34  9.................VNRTKIVATLGPACNAEGTLREMLKAGMDVARVNFSHGSAETNFALLAKLRSAAAK-EKREVAVMQDLQGAKLRVGRLPD-AGLELLDGSTVVLLAGASSAEDG---LIPVPYVTLAKEVKRGDAILLSDGLLELVVIAV-EGRRILTKVEVGGTLISYRGLTVPNRALAIEGFTDKDKADLILGINNNVDMVALSFVRTAEDVQQLKKRINRLCGDPQVIVKIEKREAIDNFDSILEEADAVMVARGDLGLETAFERVPVMQKELIAKCLVAGKPVVVATHMLSSMTLKPRPTRAEASDVANAVIDHADALMLSEETAMGRYPVRSVKTMADIIEATEESSLDNLKPERDSKGAPTQL----AVAAGAVELARQVKAAAILVTTRSGYSARAVARFRPEIPIMAVTDSVRVQKQLQLSWGAWPIYVEGYTEP------DKMVKRALQIIKKDKRISLSGQVVVVSGLKSGSGWDPTVRVVKV 480
100 0.000e+00UniRef50_A0A2M7XB35 Pyruvate kinase n=2 Tax=Candidatus Uhrbacteria TaxID=1752732 RepID=A0A2M7XB35_9BACT  ali  37  1.................MKRTKIICTIGPASEKVTTLTSMMNAGMDVARLNFSHGTHAGHRKLFQAVNKAAKE-AGKHIPIIGDLQGPKIRVGNLP-EKGVVFKAGQTVTFSTAQDTYK---NDILPVTYKGLHKDVKKGDRLLIDDGLIGAVVESV-KGQKIQAKIIDGGVITSHKGMNFPDSTLHVSALTEKDKADAVFAVNLGVDWVALSFVTEAKDVLALKRLLRRHKMPPRVIVKIEKHEAIDRFSEILDATDAVMIARGDLGVEIAAEEVPVRQKEITEAARLAGKPVVVATQMLDSMIRNPRPTRAEVSDVANAVFDHADGVMLSGESATGKYPKQAVKMMAGIIEAAEESP-----FDDVLVDTTRPSDQLETLAHTIKLMANKGAIDAVVLSYELAPWAEASLKMHPEVPLYVAARDEREARRVALRWGVIPFVMKTQKETTF-------VKQSIKKLREARKIKKGMHLGMVLGGIHGEG.......... 459
101 0.000e+00UniRef50_A0A2E1VPJ5 Pyruvate kinase n=1 Tax=Planctomycetes bacterium TaxID=2026780 RepID=A0A2E1VPJ5_9BACT  ali  34  8...................RTKILATLGPASAREDRIKRMIVAGVDAFRFNMSHGDNATRAKWVRMVKKVRKEL-NRPVSIFVDLRGPRIRLGELP--EQRKLVVGETIEVVNAKKCPRSG---ALAIDYPRLLTDLQVGHRILIRDGRAELKVKAI-EGKTLICKVKRATHLVSHQGVNLPDSAVSAPALSAKDKEDIDFAVEHDADWIALSFVRTAKDVETLQRALHRRGSNMPICAKIEHPSAIENLDEIIEATDAVMVARGDLAVEVGHAKVPMLQARIAQACLAKATPVIVATQMLESMISSPQPTRAEVSDVANAVMDAVDAVMLSGETAVGEYPVQTCQVMHDIIDQTEEEMFHWRLRPNVERRGRDQAGVGMAVANSAVFAAHLAKAKLILAFTESGRTARLVASFRASRPLICLTARESAYHRMALIWGVLPGLIREPRT------VLELHRLAADVLVERRWLRDKDLLVSLAGTFSVAGGTNTMRVIR. 476
102 0.000e+00UniRef50_A0A2G2N5B1 Pyruvate kinase n=5 Tax=Alphaproteobacteria TaxID=28211 RepID=A0A2G2N5B1_9RHOB  ali  34  1.................MRKAKILATVGPASAAPDTLKLLHEVGVDAFRLNFSHGNHEDHARAIKHIR-AVEKSSGNSIAVVADMQGPKIRVGTFEGGE-IILRYGEIVNLETGEHSDKEG---LIRLPHPELISALSVGDALKFDDGKLMVTITEK-SATRLKARVDVPGGLKNKKGVNVIGTVLPMSAMTDKDKIDMDFALAQKVDFIALSFVQTAQDVRDARAIIGDKAG---LIVKIEKPSAVDDIEAILKLADAAMVARGDLGVELPLEQVPVVQRKIITVARALGKPVIVATHMLESMIDAPTPTRAEASDVATAIYQGADAVMLSAETAVGRHPATAVAIMDRIIKAAEADPSYPDFY--TRANLRPQATINDAISQSIRGIAEVLGVKAVLGYTKSGSTVRRIARERPPCPILGMTPDKAVASRMALTWGVRPVVMPD------PKSFDEMLKITQIIAKTQADALPGDKIIIAAGIPFGPGTTDTLKIATI 469
103 0.000e+00UniRef50_A0A2E4K7G4 Pyruvate kinase n=31 Tax=Bacteria TaxID=2 RepID=A0A2E4K7G4_9BACT  ali  35  1...........MKKKILINKTKIIATIGPSSYXKNILEEMIISGIDAVRLNFSXGEYNEHKKVIENTRKISNNL-NXPIAIIQDLQGPKIRIGKIKNNK-VKLIDGQNLDIQLNEVI---GSNTSISISNKFFFQDIKPDENILIDDGKIK-LKVLSKKKKLISTIVERGGLLKSNKGVNLPDTDILLSSLTEKDXKDLKFGLENGVDWVALSXVRSSKDVDDLRKIITSXKLKTKIIAKIEKPQAIKNIDKIIQSSDALMVARGDLGVEIPMESVPIYQKRIVNKCNKQFKPVIIATQMLESMIDSKTPTRAEANDVANAVLDGADAVMLSAESATGKYPILTVKSMDKIIHSVEKNSNYNKFFEKNKSLSDREND---SLIRSACRLSRLINSKAIVTMTKSGYTGLRVSGHRPKANILIVTNNKNLLNVMSFTWGIRGIIYDKN------DYIDNTIENIESLLIEKKFLKKKDKYIITASMPSWKGHTNMMKVSRV 477
104 0.000e+00UniRef50_A0A2A5XTJ0 Pyruvate kinase n=217 Tax=Bacteroidetes TaxID=976 RepID=A0A2A5XTJ0_9FLAO  ali  32  2...............KRIKKTKIIATLGPSTSDADCIEKLINGGVDVLRINFSHSSHKEAEALIKDIRQVNTKL-NTNTSILADLQGPKLRIGDIRPDT--NLKDGNKISIKTGEEFI--GDEKTIFINYQSLPNEINTGEKILIDDGKIILKVTDTNKKDEINAEVIQGGDLFSNKGFNLPNTNISQPALTEKDIKDAVFSAKQNVDWIALSFVRHESDVKSLIKLLEKKDHRIPVIAKIEKPEGVKNIDNIMKYASGVMVARGDLGVEINATEVPLIQKKLVYKAKKARIPVIIATQMMESMMESLNPNRAEVNDVANSVMDGADAVMLSGETSVGKHPIEVIQTISSIIGKVENSNLISLKHKHPTDYDSE-RFITKSICYYAAKIANDTNAKAISTLTNSGYTAYQISSWRPKTHVLVFTSNKRILTQLNLLWGVKAFYYDS------TESTDKTVEEINKIAFDNNYLHKDDKVINLTSMPIHKGMVNTVRVSKI 476
105 0.000e+00UniRef50_A0A2M7UCL2 Pyruvate kinase n=2 Tax=Candidatus Marinimicrobia TaxID=62680 RepID=A0A2M7UCL2_9BACT  ali  31  14.................VRKTKIIATVGPASDSKAGLNDLLATGLDAVRLNMSQRDLVYYADIIQRIREWHSEFETVGPAIMVDLAGPKIRTLNFSSG--WDLKTGEVVLLGCEGAVDPT---EGIPLTGEFRFQGINPGASISADDGKILLDVTTTISNVLVEVKVRRGGLLLPRKGVNFINIELDVPTLTAKDAADFEFALDQEVDWVALSFVRRASDFNALQQIMDRKGKTIPVFAKIEKPEALDDLEAIVEQFDGVMVARGDLGVEVPIERLPAIQKQIIRRANMAGKPVIIATQLLATMQDNPYPTRAEVTDVANAVYDGADALLLTGETAVGKFPFETILQMDRIISEVEKDPEIDPRMAVIIPSQTD----SDAISHAAGEIANLLNIKVIVTMTHSGATASSVSKYRPHATIYSMTPFLPVARRLKLTWGVRPIVVQPYTT------TDEMLAFAEEKLLAMGAIQTGDSFILSAGIPIGKGSTNMLKIQSV 482
106 0.000e+00UniRef50_A0A2G4JD76 Pyruvate kinase n=5 Tax=Acidobacteria TaxID=57723 RepID=A0A2G4JD76_9BACT  ali  34  3................TVRHTKIIATIGPASSAPHILDELIAAGVDIVRLNFSHGTQADHAEKFRMIREAA-KRANRHIAILQDLSGPKIRIGRLADGKPIVLEPGASLVIAIGDDVGGPG---RVFTTYAELALKVSKGDRLLIDDGKLELEVVS-ASPAEIHTRVIDGGELGEHKGINAPHVPLR-SEMTEKDRRDLAFGLALGVDMIALSFVQAADDITRARAVMVEAGPKVPIIAKLERPEAIDHLDEILDASDAVMVARGDLGLEIPLERVPRVQKEILRQAHARGVPAIVATQVLESMRLEPRPTRAEASDAAGAVDSGADAIMLSGETATGRYPVRSVEVLDAIIRDAESM----PLPWAVVEGQQASVGHTRALSEAAVTLARRSGAHAIVAVTREGQTARLLSAARPPAIILAATDNEEVARRLNLWRGVVPMVCD------LRGDIEEVISRVVDGAVKRSKAPDNATLVFVTAADLDRGGSNFVRIRRV 472
107 0.000e+00UniRef50_A0A068NSN6 Pyruvate kinase n=4 Tax=Bacteria TaxID=2 RepID=A0A068NSN6_9BACT  ali  35  3..................RRTKIVCTLGPAVDSRDKIHALIEAGMNVARINCSHGDWDTRRRWIGWLRELSPDIA--PVAILADLQGPKFRVGMLPGDT-LELVNNSTVRVGSGEGV-------EIPIEQAEILRAMTPGGRLLLGDGEIELRVVVGVTPTVFEAKVVCGGTLRSRKGVTLVGKAFDVPALTPKDVIDAEEAVKAGVDFVALSYVKSAADARELRRLLERLGSRAGICAKIEMRQGIQDLDNILKVVDLVMVARGDMGLQMEIEDVPLMQKRIIQDCTLAGTPVITATQMLESMIHAPRPTRAEATDVANAILDGTDAVMLSGETASGSYPVECVRTMARIAEKAEGLYDRTKIEREYERH-RDAVGHTDAIAHAVSDLAQILRPRAIVCTTTSGQTPRLVSKFRPRVPILCATASESTLHQMAVVWGVEAARIPSPAS------TDETIRDAIDEFFRRKRLKIGDEIIVTAGVPAGPGNTNMILTQTV 468
108 0.000e+00UniRef50_G7JZV6 Pyruvate kinase n=18 Tax=Viridiplantae TaxID=33090 RepID=G7JZV6_MEDTR  ali  33  78...................KTKIVCTIGPSTSSRDMIWKLAETGMNVARLNMSHGDHTSHQKAIDFVKQYNSQFQDRVISIMLDTKGPEVRSGDVSQ--PILLKEGQTFNFTINRGV---STQDTVSVNYDDFVNDVEVGDVLLVDGGIMSLVVKSKTKD-LVKCEVIDGGELKSRRHLNVRGKSATLPSITEKDWEDIKFGVDNEVDFYAVSFVKDARVVYELKEYLKRHNADIHVIVKIESADSIPNLHSILSASDGAMVARGDLGAELPVEEVPLLQEDIIRRCHRMQKPVIVATNMLESMIIHPTPTRAEVSDIAIAVRKGADAVMLSGETAHGKYPLKSVKVMHAVALRNESSVLRSDSYPNHLSFHKSHMG--AMFAFHATIMSNTLNTP-IIVFTRTGSMAILLSHYRPHSTIFAFTNEGRIKQRLGLYHSVMPIYM------QFSNDAEETFARALKLLLIKGHLNEGQYVTLVSGAQWREESIHHIQVRKV 546
109 0.000e+00UniRef50_A0A0R4J2N4 Pyruvate kinase n=5 Tax=cellular organisms TaxID=131567 RepID=A0A0R4J2N4_SOYBN  ali  32  66..........SLHSSDVRRKTKIVCTIGPSTSSRDMIWNLAQAGMNVARLNMSHGDHASHLQTIDLVKEYNSQFQDKVVAIMLDTKGPEVRSGDVAQ--PILLKEGQEFCFTT---MRGVSTHDTVSVNYDGFVNDVEFGDVLLVDGGMMSLAVKSKTKD-LVKCEVIDGGELKSRRHLNVRGKSATLPSITDKDWEDIKFGVDNQVDFFAVSFVKDARVVHELKHYLKSHNADIHVIVKIESADSIPNLHSILSASDGAMVARGDLGAELPIEEVPLLQEDIIRRCQIMQKPVIVATNMLESMINHPTPTRAEVSDIAIAVRQGADAIMLSGETAHGKFPLKAVKVMHTVALRNESSVQSGVSYPSQLSSHESHMG--EMFAFHATTMSNTLNTP-IIVFTRTGSMAILLSHYRPYSTIFAFTNEARIKQRLALYHGVMSIYM------QFSNDVEETFSRALKLLLSKSHLHEGQHVTLVSGAQWREESTHHIQVRKV 543
110 0.000e+00UniRef50_A0A1V6HYP4 Pyruvate kinase n=1 Tax=Bacteroidetes bacterium ADurb.Bin035 TaxID=1852799 RepID=A0A1V6HYP4_9BACT  ali  32  3...............KKFLRTKIIATIGPTSWNKETIEKMLLAGTNVFRLNFSHFNYEKFEEIINIIRETSTALK-IPCAILADLQGPKLRIGEIKEGT--ILKNDSYILITNKEII---GDENGFTLRYNN-FNELHKGDQVLIDDGKIILRIEEILNEKEIKAKVIRGGLLLSQKGFNIPQANLSIPSVTEKDKEDIKFIINHDFDWLALSFIRSANDIIQLREYLESLNSDISIIAKIEKPEALKQLNQIISLSDGVMIARGDLGVEMPIYQLPIWQKRIITRARQLAKPVIVATQLLRSMIDDIIPSRAEVTDIANAVLDGTDALLLTDETSLGNNPILVIETMAKIIGEVENNPEFNKLLTRNFKMASPLNKIQYVTASIAADVVLTYPISAIIGLTYTGSSIIQISSYRSPVPIFAFTSQNKVIRKLSLIWGVRSFFYDN------QNSTDETIEDTLNFLKENEYLESGDWVIHTASMPINAKHINTLKISIV 479
111 0.000e+00UniRef50_A0A1F6LJE4 Pyruvate kinase n=44 Tax=root TaxID=1 RepID=A0A1F6LJE4_9BACT  ali  36  3..................KSTKIVCTIGPASDKYEVLEKMQKNGMNVVRLNFSHGNHDEYLNVIKRVRRL-EKASGEPIAIIQDLQGPKIRVGELPTEG-IELSSGQKIIF---NYLIKECVGNQITIDYP-LHNFVKKNERIFLNDGHIETKVISIQ-GSKIICKVKTGGLLTSHKGMNIPDTKLNLTSLTKKDREDVCFGIEQKVDFIALSFVNSSKDVKALSRLINKHKNKIRIISKIERHEAVENIESIIDVSDAIMIARGDLGIEIPIQKVPMIQKKIIAQCIKKEKPVIVATQMLESMKYSPDPTRAEVSDVANAVIDSADAVMLSAETAIGHYPDLAVAVMSNIIEEAERSEYDNLPTKKYSNLSKDVDDIISGLSR---MLAEGIEAKLILSASVSGDTGRLLSSYRPDTKIVILTRTEIVNRQLNLSWGVRPYKYGEFSS------IEEMSKKSIELLHKKKILKKKDKIIIVAGEPIGAGHINLLEVREV 477
112 0.000e+00UniRef50_A8ERF9 Pyruvate kinase n=24 Tax=Campylobacterales TaxID=213849 RepID=A8ERF9_ARCB4  ali  36  3..................KRTKILATLGPASHTIEMIEGLIKAGANMFRLNFSHGSHEYHLETLNNIKTAM-KNTGKTVGILQDISGPKVRIGDLK--EPFSLTRGDILTFVKDEIYKKADKEYIVSINYPDILGKIKVDEYIYLYDGTIRAKVIKV--GDEVQARIENNGTLSSKKGVNFPNTVIDIDVITKKDEKDIAWGIENEVDYFAISFVQNARDMRRARSLL--NGYRGKLIAKIEKFDAVANIDEIIEASDGLMVARGDLGIEVPYYDVPTIQKMLIKKANLKGIPVITATQMLLSMTQNERATRAEISDVANAVLDGTDVVMLSEESAVGEDPVNVVDTMHNIIAKTEGIYDYDKQYK------MSYLDEFDVIQATVTKLADDLGADGILALTSSGKSAVKMSRYRPKTPIYTFTHKKKVLNSLTAIWGIEPVAVIKEAQAS------KMFQKMLKNLDQKGILNRKGIYVATVGYPVGPRSTNTIKILT. 467
113 0.000e+00UniRef50_A0A0S8EHX4 Pyruvate kinase n=1 Tax=Planctomycetes bacterium SM23_25 TaxID=1704028 RepID=A0A0S8EHX4_9BACT  ali  32  2.............AHIPVRLTSIVATLGPSASEEAVLRQMIEAGMDVARLNFGHGSQETHSGLLARLRRTAEAC-GKFVAVLQDLAGPKLRVRTPHGET-LDVRAGDHIRL-CREVRDDAG-ACDLGCTHPGVVDDAAPGDAVLFADGDIVTRVAERAEDHLVL-ECEEGGTLSPGTGINLPQTDLKVSLPTDQDWQDLEWGLAHEVDYVGLSFVRTADEVRRVKDFIAKAGSEARVIAKIEKPQALDEIDAILAECDGLMVARGDLGVEMDVARVPVIQKDLIRRAAAAGVPVITATQMLQSMVVEPRPTRAEVSDVANAVFDGSDAVMLSGETAVGRHPVRAVEMMDHIIDLAEDYAERTDWQAPAARQERYVWS-ERAIVAGATGIARSLDPALIVALTHTGATALLMSKQWLRVPILAVSDSLATCRRMALYRGVTAVHSPDLIGH------ERLAAAVERMARERKLIVAGDRILIISGFPGKPGGTDTLRVHTV 477
114 0.000e+00UniRef50_A0A2A4RR12 Pyruvate kinase n=1 Tax=bacterium TaxID=1869227 RepID=A0A2A4RR12_9BACT  ali  30  1...MSHSSAPSWMPKDSTRHAKIVATLGPASDSDEMLEKLIEAGVSVFRLNFSHGSLEDMETLLIKVRRAI-DNSGRCIATLGDLQGPKMRVCDIHDGGGIMLNKGDEVYFGLGDAAIVDGNPS-FDVTFNSFYEDVLPGQRVLINDGLIRMLAVEQEKGSWVRCQVTAGGKVTSSKGVNLPDSELDMPAITERDWKCAKWACEHGLDYLALSFXRTADEILELKAKLEEMGTSIPVVAKIEMPQAITNLDSIIEATDAIMVARGDLGVEMDVAQVPIIQKYILAKCSALGKPCIVATQMLETMIESVTPTRAEASDVANAVFDGCDAVMLSGETAVGAHPRVVVETMQRIIKVTESRMDQIVHTSGLPTDMKEYPFRSAALAKGVWHMADQLNAKAIVVWSQAGGMARYLSQFDFRVPIYGYTSSKMAANRMALYGGVTPIFTQPPESGRLRDWTDQ----VENLIRAEGITKDGDAVLLVAGKPLGA........... 499
115 0.000e+00UniRef50_A0A1B2YXT8 Pyruvate kinase n=3 Tax=Bacteria TaxID=2 RepID=A0A1B2YXT8_9BACT  ali  33  3..................RKTKIIATIGPSCSKPSVLKKMIQKGVNVCRLNFSHLSLEKAKEIISSVKTINQQLS-VHTAIMADLQGPKIRIKKIHN------KTGELSTMVGQKIRIGNSKDCDLSVDYRGFAKDIKKGDSVLIEDGKIILKVLETDKKTNTTLKSLSSGVIKERKGINLPDTNIKMNSMTKKDFRDLKFVVSENIEWIAMSFVRKKEDVISLQRRIKKSASTARVIAKIEKPEAVKNIDEIIDCADGIMIARGDLGVEIPAHKVPVLQKKIVNKCRFASKPCIIATQMLESMTNNFSATRAEINDVSNSVFDGADALMLSGETSIGIQPLKVVDTMRKTIKDAEKSM-EDFEFKKIKGRVSTKRKVADNICKNAVKAANDLHAKSIITATYSGYSALKVSSYRPKAFIYAFTNNHSILNTMSIFWGVVGIYYDRGST------TDQLVQETIEILQKNKIVKKGELVINTASMPAKKGGTNTLKISRV 471
116 0.000e+00UniRef50_A0A2C6CS35 Pyruvate kinase n=21 Tax=Bacteroidetes TaxID=976 RepID=A0A2C6CS35_9BACT  ali  32  4...............TDHQNTKIVATVGPACSSYEKLLELVKVGVDVFRLNFSHGTHEDHGAVINHILRI-KEETNVHVSILADLQGPKLRVGKMEGEG-LQVEEGQVITFTNEECI---GNAERIYMSYAQFARDVTVGEKVLVDDGTLVFEVVKTNGQDEVELKTLFGGLLKSNKGVNLPNTQISLPSLTDKDLIDLEYILTQPVNWIALSFVRHPKDLRDLKERIDAAGHPAKIIAKVEKPEAIERIDKIIKHSNAIMIARGDLGIEMPMKQLPILQKMIIKKCIQRARPVIVATQMMDSMITNPGPTRAETTDVANAVLDGADAVMLSGETSVGRHP-KLVXXXXXXXXXXXXXXXXXXXXXRPKPSPKSRTFVSDMICASAVDVAEGINAKAIIGMTSSGYTAFKLSSFRPAAKTYIFSDRQHMLATLNLCWGVRCYYYDGYSS------TDDTIEDVVGILRQNKRVAVGDMVVNTASMPIQRRRTNMLKVTSV 477
117 0.000e+00UniRef50_A0A2E4JPD4 Pyruvate kinase n=1 Tax=Thaumarchaeota archaeon TaxID=2026795 RepID=A0A2E4JPD4_9ARCH  ali  34  1.................MRKTKIICTIGHFSASASMIEKLAKAGMDCARLNFSHGTHAEHLRVINLIRKVSTKI-GKEIAIMQDLPGSKLRVGKLEKG-SVYLKRSSFLSLTTEDIV---GNEKRIPVGYDDLPRYVDNGTTIFLSDGSIRLIVLDKN-NIEIKCKCEIGGELLPGKGVNIPQLKHDFKTFTSLDKEHLEFGLKNDVDLIAVSFVRKASDIEYVRKLVNKSN-DCSIIAKIEKKEAVDNMESIIEVSDAVMVARGDLGVEKSLEQVPMIQKSIISHCNNKAIPVIVATQMLESMINNSTPTRAEVTDIATAILDGTDSVMLSDATAVGKYPVECVQMLHRVSLTAEEKIASYTRY--TTNSGSIHKDIRDVVCEAANQISLDIGAKLLISPTNSKEMAPKISRFRPKAPIIALTDNQKTIRKLKISWGVYPI------QTNKEDNLTNLLETSIKRLTEENLIKRGDRAVII.................. 450
118 0.000e+00UniRef50_A0A1Z9LYF5 Pyruvate kinase n=1 Tax=bacterium TMED198 TaxID=1986779 RepID=A0A1Z9LYF5_9BACT  ali  31  1.................MNRTKIVATIGPATFSSKNIAKLLDEGVDVIRLNMSHISSSETKDIIARIQKISNKKS-KFIPILFDLAGPKIRVKHTFLN--FKITKGKSYTLGSSSVAD-------IPINYKLKIKSIAPNAQVKIEDGKIAFKVIEK-KDHCLVIRALKSGIVKPSKGVNLPGVDLTLPSITKKDRRDLKLGLDLGVDWIALSFVRKASDIRNIKKIISSLNTKVPVMAKIEKPEAIENLDSIISESDGILVARGDLGVEVDYEKVPVLQRKIIQKCRIASKPVVVATQMLESMIKKSSPTRAEVNDVASAVYDNVDAIMLSAETSIGKFPFESVRVMRTIANKLE--LEEVNNFYHKKKLENRLDTVQSAISHAVFRLTSDLDINAVVVMTESGSTCRFVSSYRPKAPIFALSPYESICRQMSIIWGVVPLKVDSLI------DTDKMIGVAEKILKRKKMIQKNQLFVITAGVPVGVGTTNMLKVHKI 466
119 0.000e+00UniRef50_A0A2D6ZYN8 Pyruvate kinase n=2 Tax=Bacteria TaxID=2 RepID=A0A2D6ZYN8_9RICK  ali  35  7..................KRTKIIATYGPSCKNIKVIEHLIQNGTDLFRLNMSHDDPQELATIVKNIRKTAKKL-DKHVGIFCDLQGPKIRVGEFSNG-PVHLKKNNLVTLTSEKV---DCTDKKMFVDYKNIANDVKIGDVVYIDDGKLSLTV-SKVDNNDVICKINVGGKVSNHKGVNFPHTVLSIPAFTEKDKKDTLTGIKLGIDYIALSFVSTKYDVVSFKEYLNSGGNDIKVISKIEKKQAVENYLGIIEQSDAIMVARGDLGVEVGIEHVPKLQKEIVQECNKKIKPVIVATQMLESMIHSTTATRAEVSDIANAIYDNCDAVMLSGETAVGXDPANVVKVMSEICSAADLHIKMKQETIMYRKKIFEFDTVATSICKAADQIAEENDARVVMSFTXSGNTPLIASKINSTIPIISPTDDENICRRMSLYKGVTPMMMPKMYSDIQRWT--DMIKIAVKHALNLEWVSKGDRIVVTAGIPIGSNGINSIRIINI 484
120 0.000e+00UniRef50_A0A2E3UVV5 Pyruvate kinase n=1 Tax=Zetaproteobacteria bacterium TaxID=2026807 RepID=A0A2E3UVV5_9PROT  ali  35  46..................KHCKIVATIGPASQDPQILEELICAGLDVARLNFSHGTEKNHAQTIEKIRQISKKL-GKNVSILQDLQGPKIRCGQLKNEQ-INIEKNKIYKLTFGNKQE---SNDVIPVDYNDLSKDINLDEIIMMDDGLLSFKVIKIEGEEIEI-IALNSGVLKSRKGVNFPNTQLTLPPLTEKDKKDLLFGVSQNVDAIALSFVRQASDIKSCRKLLTTLGSDIPIIAKIEKTSAVEFIDDIAEESQGLMVARGDLGIEGKIEKVPGFQRKIIAAAQKNTIPVIIATQMLESMIEAPKPTLAEINDVANGVLEGADCVMLSGEVAAGKYPVECVKKMSSIIETVESWSKKQISFHKPHSSNNNAWQIHEAIAKSACDAANSFNAKIIVCLTLTGSIARLISSWRPACPIVAISPRNDIVKRLLFSWGVYGF------RNPLFYETDILLQDLPLLLKSSNIVRSKDKIVITAGVPMNSSSTNMIKITEI 520
121 0.000e+00UniRef50_A0A2M7UNX6 Pyruvate kinase n=3 Tax=unclassified Candidatus Peregrinibacteria TaxID=1801912 RepID=A0A2M7UNX6_9BACT  ali  34  4..................KNTKVVCTLGPSSDSINELLALIKAGMNIARLNFSHGTHEHHLKLIKNIHKAESLMKTR-IGILQDLQGPKIRIGEMPPEG-IQIKKDEVFTITIKEITGEKTHKTIIPVTYKNVCRDVKKGATVLINDGLLESVVINKKKDELIL-KAKTSGIIKHGNGINFPNSTISAKTITEKDLKDLEFGLNNDVDFIALSFVKSKKDIEDLRALIQKKGKNTPIIAKIERHEAVSHLKEIIKATDGVMVARGDLGTDIPPEHIPLVQKRIIHLANKHGKPVITATQVLQSMVKNPIPTRAEISDAANAVFDHTDAIMLSNETAVGKYPARAALVLTKVAHSVEQEMEKHKELKEYNFSSKQKTRSSLIACENACDLTVRAKAAAIITYTDDGFTPKQIAKYRISTPIITFTSSEKTARELTLVWGINKVFVKKFPLDANKK-----LQNIVNFIAREHLVKKGQKIVIIC----NASSTSTI..... 469
122 0.000e+00UniRef50_A0A2T2R903 Pyruvate kinase n=1 Tax=Actinobacteria bacterium QS_8_72_14 TaxID=1919086 RepID=A0A2T2R903_9ACTN  ali  33  14............DWTLRVRRAKIVATLGPALDDEDQLAPALEAGIDIVRLNFSHGEHDTHAKRLNRVRELAGQ-QGRNVASLADLQGPKIRLGVVPSGG-VRLEDGGQVVLVPGESHVDADGTPALPVTYHALAQDVQPGALVLVDDGLIRLVV-SRTDGETVVARVVVGGRAESRKGVNLPGVRVSAPSLTDKDAEDLQAAVELGVDWVALSFVRHPGDLDVGRQRVADLGGEAPIVAKLERSEAIENLANVVQAADAVMVARGDLGVEIGSERVPAIQKEIIHRGNDESRPAITATEMLESMLTSPRPTRAEASDVANAVFDGSDALMLSGETAVGHYPVESVRTMARIIEVAESS----PHLIHPQPPHLGEREIRRVVASSACRVAEDVGATALAVFSITGGALQLVSTFRPPVPIVGLTPSELTRRRSAMLWGTEAVLVP------MKDQAGDLIEAAERMLCDGGWVSSGDRLVILSGLPRAGGSTNRILVHTV 492
123 0.000e+00UniRef50_A0A1F3J2N8 Pyruvate kinase n=1 Tax=Bacteroidetes bacterium GWE2_42_42 TaxID=1797339 RepID=A0A1F3J2N8_9BACT  ali  34  2.............SEITLNHTKIIATIGPASASPEMLRALVDAGMNVCRLNFSHMEYAKATEIIEEIKTINSE-TLFPVALMADLQGPKLRVGNMGCDGA-ELKTNELVIITSEEC---EGSAERFTLRYPMLSRDLKPGERILLDDGKMEVHITRVLNEKEVEAKVIRAGILKSNKGFNLPGSNVSLPALTEKDLKDLEFALSADVDWVAISFVRRPEDVIELKKRIADSGKTARVIAKIEKPEAIEHIDEIIEAADAIMIARGDLGIELPLQEVPILQKNIIQKTITAAKPVIVATQMMESMMTSTMPSRAEVNDVANAVTDGASAVMLSGETSVGMFPVETVATMHRIIIDVER--DSRPYTKGAMPKSEDEVSTAYEISFMASRMAKFMNAKGIVVMTATGTSAVRMSSFRPKSHIFVFSNDHKLLRTLMLAWGLRGFYYDDFQS------TDQSICDTIATLKLHNLVSEGDTIIHTASMPIAQGRANTIKVSVV 476
124 0.000e+00UniRef50_F0Y514 Pyruvate kinase n=1 Tax=Aureococcus anophagefferens TaxID=44056 RepID=F0Y514_AURAN  ali  39  1...........MSSAAQTKKTRIICTLGPACWSVEMLGVLLDEGMNVARLNFSHGDHPTHARTIGRLKEALALRPGVHCAIMLDTKGPEIRTGFFYADGKIELKAGAPLTLTTD--YDYKSDGTKLACTYGKLPQSVAPGNQILIADGSLVLEVKQVLSATEVACVVMNDCAIGERKNMNLPGVVVELPVLQDKDTKDLEFACPQGVDFVAVSFVQSAADVQTVRAVLDGAGGKIKIISKIENQEGLANFEGIVAATDAVMVARGDLGMEIPPERVFVEQKMMIDSCGAAGKPVIVATQMLESMCGNPRPTRAECSDVANAVLDGADAVMLSGETAGGKFPREAVAIMARTCVEAEKQVDVAAAYLRAHAHLKRGASVVESTVAAATQAARDAGAKAVVVIAQTGATAQLFAKYKCAIPLVVVTAHAHVARQSALIPGCQALHTPNYGYDASGDDEAAMVLEGAKCAFALGHLHVDDIVCAVHSYKVGV........... 489
125 0.000e+00UniRef50_A0A2D6GU64 Pyruvate kinase n=14 Tax=Alphaproteobacteria TaxID=28211 RepID=A0A2D6GU64_9RHOB  ali  33  2................HQRLCKIVSTIGPATSSPDMLRMIHEAGVNVFRLNMSHGQHDKLRNVVKSIRE-MQVETGVATAIFADLQGPKIRTGTFEDG-SIQLRYGQEYRLVNASSTTEEG---VIPVPHQEVFDALDEGAVIKLDDGKLQMTVTG-RDGDALIARADAMGTLSDRKGINIPDRSLPISALTEKDREDLEFALSMKVDYIALSFVQRPSDVHEARELIGDRAG---IISKIEKPSAIEHLDEIIEASDAIMVARGDLGVECPVEDVPIMQRRIIRACRRVGKPVIVATHMLESMVESKAPTRAEASDISSAVNQGADAVMLSAETAVGSHPQTAVAIMDRVISATERDP--ETACYAIFHSEEDHSTTADAVSLSARRITEVLECRFAVAYTNTGSTARRLARDRPYAPILAATPNVEVAQSLSLCWGVTAKVTEDIS------DFGEMIARADTLASEAG-GENGERIVILSGFPFGSGKTNTLKISRI 468
126 0.000e+00UniRef50_H3G361 Pyruvate kinase n=1 Tax=Pristionchus pacificus TaxID=54126 RepID=H3G361_PRIPA  ali  42  1.......................................MILNGMNIARVNMSHGNRDAHKRRIRMIKEAREAFPDHYVAIALDTKGPEIRTGPVKDHVPLKLKEREGYT---------------IYLDYPFIAEQLEIGKDLFIDDGVICLRVLAKHSEG-LHCEVITGGHLGSHKGVNLPSVRVRLPILSERDKEDLRLVIEEHVDLVFASYIRNRREVETVKYEISDSAKPISVIAKIENEDSLKNIDEIIDAADGIVIARGPLGVETPSAKVAIVQKMIVSKCNRNCKPVIIATQMLESMTLNPRATRAECSDVANAVLDGADCVMLSAETAHGKFPVGAVTVMNNICAEAETAYYQQSLLQDLRRQKGGTLNKLETMALSAATAVSCMNASAIVMITTSGKSAQICAQFRPPVPIVALCASKAIARKLHLYRGVLPFYVPETKVGPKMDVIEQALQMGIDQCKKRGFVKTGDPVVLITGWP.............. 431
127 0.000e+00UniRef50_A0A0S7X8T8 Pyruvate kinase n=1 Tax=Deltaproteobacteria bacterium DG_8 TaxID=1703397 RepID=A0A0S7X8T8_9DELT  ali  34  1.................MRGAKIVATIGPTSSSIVRLEELIKSGVDVFRLNFSHSTFDEHEKVFLNIRRAAQNVRRHP-AILQDLPGPKVRVANLR--TPLNLTKDSVVTITFGKFKHYG---YGFSINYPSILKAIKVDDPIIIDDGLLRLKVIEKI-NSAIHCLVEVGGLLKPHKGVNFPTSDWKTPVLTSADKNALIFGITHDIDFVALSFIADEKSVVATKRILNKHHSQAKIIAKIERPAAVHNLDGILDVADGVMVARGDLAIETSLEKVPFLQKEIIRKANAKNVAVIVATQMLESMTEHAMPTRAEVSDVANAVLDGADALMLSAETAVGSYPAKSVRMMDHIIREAERH--EKHLFIHDISKPADTRNLSEVISHAAMVSAGDLKNDKIVLFTISGKTARLLSKYRPSADILAFTPSKKTMHQLNLEWGVKPLYMD------YKKDTEQMVSEAIHRLRKMKLVKRNDFLIFIIGKIPGNYANNFL..... 463
128 0.000e+00UniRef50_A0A2E5GZH0 Pyruvate kinase n=2 Tax=Gemmatimonadetes bacterium TaxID=2026742 RepID=A0A2E5GZH0_9BACT  ali  34  1.................MLRTKIVCTIGPSTSTRSAIRALIEGGMDIARINMSHGDHETHTETIAGLRQTAGEL-DKNLGILVDLAGPKIRVCGL--EEPLLLEVGQTVTIAEDLSEHVA----DMSVTSFDLLGVLTRGDSILLDDGGLELSFVELKEG-LVVSEVVRGGELTEGKGVNIPNVNVESTFITEKDMKDLEFALKKEVEYIGLSFVLSSGDVRRLREKIPEK---TLIVAKIEKAKALDSLGDIVDSTDALMVARGDLGVELPFERVPRAQKRIIRWGNFGARPVITATQMLGSMMINSRPTRAEVSDVANAILDGSDAVMLSGETAIGEYPIKSLEAMVSIIREVESSLEQGPLYGTFSGNHKRGGATPHAVASATVEVARQLEVPAVIVITRSGFSARLVSSYRPKAPLFAVCTDSYTCRQLAAVWGVYPVLAEDVE-----VSYEALSQFGKTFVLGKGLGQSGDSIVVTAGSPFNSGTTNTMRVEV. 471
129 0.000e+00UniRef50_Q93Z53 Plastidial pyruvate kinase 3, chloroplastic n=36 Tax=Mesangiospermae TaxID=1437183 RepID=PKP3_ARATH  ali  33  99..................RKTKIVCTIGPSSSSREMIWKLAEAGMNVARLNMSHGDHASHQITIDLVKEYNSLFVDKAIAIMLDTKGPEVRSGDVPQ--PIFLEEGQEFNFTIKRGVSLK---DTVSVNYDDFVNDVEVGDILLVDGGMMSLAVKSKTSD-LVKCVVIDGGELQSRRHLNVRGKSATLPSITDKDWEDIKFGVDNQVDFYAVSFVKDAKVVHELKNYLKTCSADISVIVKIESADSIKNLPSIISACDGAMVARGDLGAELPIEEVPLLQEEIIRRCRSIHKPVIVATNMLESMINHPTPTRAEVSDIAIAVREGADAIMLSGETAHGKFPLKAVNVMHTVALRTEASLPVRT---SASRTTAYKGHMGQMFAFHASIMANTLSSPLIV-FTRTGSMAVLLSHYRPSATIFAFTNQRRIMQRLALYQGVMPIYME------FSDDAEDTYARSLKLLQDENMLKEGQHVTLVSGSQWREESTHLIQVRKI 567
130 0.000e+00UniRef50_A0A2D5C7U1 Pyruvate kinase n=6 Tax=Actinobacteria TaxID=201174 RepID=A0A2D5C7U1_9ACTN  ali  35  14..................RKTKIIATVGPSLLSENKIHKVVQQGVDVLRLNFSHGSMEDHENVIKW-----AKSSKKSVAVMQDIQGPKIRTGSAKKDT--VLKKNEEISITNKEC---ESDEKNIFVNYEDLIQDINIGDRVFIDDGQVVLKVVEKNK-STLIALILIGGELRDNQGVAFPDSNLSVSAITPKDIDDLKFGVDNDVDFVAVSFVRNADDINTVKKLI---PKDIKVIAKIELKIALDNIEEILEVSDGVMVARGDLGVQLPIEQVPFVQKQILNAANSRGKISITATEMLQSMKTSYRPTRAEVTDITNAILEGTDAVMLSAETSIGDHPNRVVEVMSTICSETDARNDTSTLR---FKELSSIDELTTTLARAAVQVANDIDARAIVAFTESGRTPLLISNYRPKSPIITFTSKSKTYNQMSLLWGVEQYKIERKNT------FEEMLNDANDFLKNEKKYNKGDKVVVVAGTPPNVEATNLIRVHRI 473
131 0.000e+00UniRef50_A0A2M6WC10 Pyruvate kinase n=2 Tax=Parcubacteria group TaxID=1794811 RepID=A0A2M6WC10_9BACT  ali  34  1.................MKRTKIVATIGPACDSQAVLTKMIKAGVNVARFNFSHGTYASNKKAVSSLRAVAKSL-NQSVGIIQDLQGPRIRVGEIAKDG-LDLKKGEIVVLVDDLKKKIKSDKKIVPIQFIKPSQILKAKNKVLLLDGLIELRVTKVNANH-VEAKVFKGGIIYTYKGVNIPEIDLGLPVITDKDIKDLEFGLKLGVDYVALSFVGSAGDLKDLKKLIKDKNSEVQVLAKIERGQAVKNIKSIIKEADAIMVARGDLGIELPEVKVPIIQKEMIKMCLEQGKPVIVATQMLDSMIRNPKPTRAEVSDVANAVIDHADSVMLSGETAFGKYPVESVKMMNQIILETEKSIYDDMPPGYFLE---KKLSVTKAISESVFELVKDTKARAIVAATNSGYTARMIARYRPETRIIVLVNKQEIAHQLSLVWGIYPEMMPVC------KSLDELVEKSVALVKKQKLVIKGHQIIIVTGQPVGSKNMNLVKIHTV 475
132 0.000e+00UniRef50_B0B7Q0 Pyruvate kinase n=70 Tax=Bacteria TaxID=2 RepID=KPYK_CHLT2  ali  38  4...................RTKIICTIGPATNTPEMLEKLLDAGMNVARLNFSHGTHESHGRTIAILKELREKRQ-VPLAIMLDTKGPEIRLGQV--ESPIKVQPGDRLTLVSKEILGSKESGVTLYPSC--VFPYVRERAPVLIDDGYIQAVVVNAQE-HMVEIEFQNSGEIKSNKSLSIKDIDVALPFMTEKDIADLKFGVEQELDLIAASFVRCNEDIDSMRKVLESFGRNMPIIAKIENHLGVQNFQEIARAADGIMIARGDLGIELSIVEVPGLQKFMARASRETGRFCITATQMLESMIRNPLPTRAEVSDVANAIYDGTSAVMLSGETASGAHPVHAVKTMRSIIQETEKTFDYHAFFQLNDKNSALKVSPLEAIGFSGIQIAEKASAKAIIVYTQTGGSPMFLSKYRPYLPIIAVTPNRNVYYRLAVEWGVYPMLTLESNRTVWR-------HQACVYGVEKGILSNYDKILV---FSRGAGMTNNLTLTTV 472
133 0.000e+00UniRef50_A0A1Q7FXZ3 Pyruvate kinase n=1 Tax=Armatimonadetes bacterium 13_1_40CM_64_14 TaxID=1805026 RepID=A0A1Q7FXZ3_9BACT  ali  36  1.........MDLHPPKEWRRTCIVATLGPATSDPARIRTLLEAGINVVRLNFSHGEADEHARICGLVRDTEQQL-GRPIAVIQDLAGPKIRVGHLSNGA-VTLREGQLF---TLTTTNLLGTDREASINYPQLPRDVKAGNRILLDDGNLELVVESTTA-SSVTTRVVRGGVLREQKGVNLPNVSLDVPSLTEKDRKDLEFGLHLGVDYVALSFVRR-------------------------KAEAITALDEIIAEADGVMVARGDLGVELAPEWGPVLQKTITSKANAVGKPVIIATQMLESMVHSPRPTRAETSDVANAILDGTDAVMLSAETAIGEYPVEAVQMMDRIARVAESSNPAIFGSHGLVQHSTTASIATAA-----AALAHEGRVRAIVAITRSGLTAQLLSKLRPREPLIAFTEQEATVRRLGLWWGVQSF------TTSFMDNTDAMIDHLEDELLRRGLVEVGDTVTIVGSAPLVRGRVNFVKMHRI 451
134 0.000e+00UniRef50_A0A2P2IBH7 Pyruvate kinase (Fragment) n=1 Tax=Hirondellea gigas TaxID=1518452 RepID=A0A2P2IBH7_9CRUS  ali  37  1......................IFCTIGKSSSSADMLGRLFEAGMNVAVCDFSRESRAFHEDAIKKIR-AMEKKTRKLCAVLLATRGPAIQTGALKDGDSVRLKRGQEYVLHTDEKTM--GDDTQISVKYSEFPKLVKVGSTILMDNGAATLIVKQV-SDRRVTCQVQSDCHFGSQKTLNVPGTVLKIPSVTQRDVADIKFGVQMGVDFIAASFVRSASDIRTIREILANSGRHIQIIAKIQNEEGLRNFDEILDCADGIIISRSDLGLDIPMERVPLATKLMIRKCNGAGKPVVTATQMLQSMCLNPTPTRAEASDVGNAIFDGSDGVMLTGETSSGLYPEESVKMMALICRESEQSINYQATFQSIHERAPGPNSIAESLSSSAVKTAFDLEASVLIVFTFSGRTARLVSKYRPSAPILMLTESIAVARQGLVSRGLIPLLVGSMSGSTT------LFNRAISVAKSLRICEKGDVAVLVSGGKGDSVFSNVIRVIR. 479
135 0.000e+00UniRef50_R6STD3 Pyruvate kinase n=10 Tax=root TaxID=1 RepID=R6STD3_9CLOT  ali  33  1.................MKKTKIVCSIGPASNQPDVMEKMVLAGMNVARVNFTHATLEERKLAISSVREV-RKRTGMNIAILWDTKGPEFRSGMLENDK-IELVEGKTIRMVKEEVL---GTEEKFSTNHPEAISSLKVGDTILLENAKMRLVVESVEDDG-VTCKILAGGVLGNRKSMSVPGVKLNIPYVSDLDREDLKYACENGGEYLAISFVSCKEDVLEIKKILKEHNRDLQIICKIESQLGIDNLKEILEVSDGVMVARGDLGTEIPSEMLPIVQKRMIRTARQMGKLAIVATEMLETMMENNRPKRAETSDIANAVLDGTDAVMLSGETTVGKHPVETVQAMANICETTEKYAAFDYI-----SIKKQADNVPSAIAECVVESANRLDAKLICAATITGSTARLISNLKPNALILGLCPDEKTGRRFALNWGCYPVILPVCSS------TDEVLDKSIKCAKENMELEKGDIIVITGSFPGDNRQTNLMKIEEI 469
136 0.000e+00UniRef50_A0A2E7ZMB1 Pyruvate kinase n=9 Tax=Proteobacteria TaxID=1224 RepID=A0A2E7ZMB1_9DELT  ali  35  1.................MLHTKIICTIGPASDSAEMLEMMADAGMNVVRLNFSHGTHDSHREIVKKVRTLNLKNREFPVSILLDTKGPEIRTG----DQHLKLITGSKIQVVSDPDLR---DEKHLFVDYPYLTEQLGQGNHLLLDSGLVKLEVLD-NSGNSLKCRVLDGGMITPKRHVNLPGISVKLPGITISDRKDLKFALEEDVDAVALSFIRNRETVLEVRQMFREKGQQIKIIAKIENQEGVDNLEDIMHEADGIMVARGDLGIEIDMEELPHIQRRIAFLCAKYGKRLIVATQMLESMIENPVPTRAEITDIANAVFEQSDAIMLSGETSTGKYPVRCVETLIRIARRTENYPGVQFTENLIQEDGPDETKGRQMLAAAATRIARQLKVPGMLVITRKGRGATKMANLRVRIPIFAFTETEKTKSTLMLLRGVYPYLLK------FDEDPEQTIQNALRMLKNKQDMPSGVSIVVVADIMTGEGYVNCLQIRT. 471
137 0.000e+00UniRef50_A0A2H0LKU2 Pyruvate kinase n=1 Tax=Candidatus Omnitrophica bacterium CG11_big_fil_rev_8_21_14_0_20_45_26 TaxID=1974748 RepID=A0A2H0LKU2_9BAC  ali  34  3...............SSIRRTKIIATVGPACSEESDLLRLLQKGVDIFRINASHTDPDKLKSWIRRLRKVACQ-ANRNVPILVDLQGPRVRTGPLKNHETIKLKKGDTLIISAKK---GAGQGQIIYTDCPQLPRMVKKHDPVLLDNGLIELAVSTIHHD-EIHCRVEVGGFLGENKGINLPNAPVTLPALTPKDLKDLAIAAHEEVDFIALSFVRSRHDVMAVKRWLVKHHLSIPVVAKIEKPRAVEDIDEILSKTDAVMIARGDLGIEMQVDKIPVIQKKLIAKANERGVPVITATQMLESMIQQAIPTRAEASDVANAVFDGTDAVMLSGETAVGAYPDRAVRIMADIIRDAEK--YDDGLLLTRQNKLNVLDTKLAAISQAAVSAAKRLKARSILVFTLTGKTALFISKLGLHIPIIALTQKESISKRLQLLSGVYPLTID-----YSGKSADDLLKSCDKSVLKYGLLKRGETVVILTG................ 459
138 0.000e+00UniRef50_A0A2A5CXF3 Pyruvate kinase n=3 Tax=Candidatus Marinimicrobia TaxID=62680 RepID=A0A2A5CXF3_9BACT  ali  31  3..................NNTKIIATIGPACDDKKTLQSMVDSGVNVFRLNMSHGDESSKQKLYNLVKSLSHKNGERPC-ILADLAGPKIRITDVV--PNFVLESGQLISITNEKDA----DRSHIRVTEGVGFADINKGDTILINDGRIQLEVIDAISENTIKCQTKIGGLVEPRKGVNFPGITLNVPPLTDQDNVDLKMALKEGADWIALSFVRSANDVKEVHAIMDEAGKRLPVMAKIEKWEALNNVESIAESFDGIMVARGDLGVEIPAEQVPIAQKQMIDVSRSIGKPIVIATQLLESMIDNLTPTRAEVSDIANAVFDGVDALMVTGETAMGKYPVEVIQVLNRVIGESEQVLPSQQKF-----LPEMVTKTADAISHAVCEIALDLNINVVMTMTHSGSTALMIARYRPKTNLFALTPFAHIVRRLQLVWGVVPIKVDKY------DNVDEVPDVCKAVLDKIELIEKGERFIITGGVPMGAGTTNYLSVQT. 466
139 0.000e+00UniRef50_A0A257TS41 Pyruvate kinase n=1 Tax=Planctomycetia bacterium 21-64-5 TaxID=1970542 RepID=A0A257TS41_9BACT  ali  33  3..........DTPSTPTFARTKVIATIGPACREESQLAELARAGVDVFRLNMAHGGIEKQQANLEAVRRVS-QAAGRPIGVLTDLAGPKLRLGELPGGQ-VECCQDAHLRFVRGDVSSQ---ADELVSTYARLIDEVKVGDRVMLADGTVSLQVEERGPDVAV-CRVVQSGMVRSRQGINLPGVKLGLPAMNEEDCAHAIWAAQHGVDFVGLSFIRSPDDVLALKALLRAHSSRAMVIAKIEKPEALVRLEEIVAAADGVMVARGDLGVEIDVARMPVAQKQIVAVCNRHRKPVIIATQMLDSMQHSQHPTRAEVTDVANAILDGCDACMLSGETAVGQYPRAAVEMMNRIALATEPLLRGRAAQPISDVRIEDLHRVTEAVVYGVQFIASQLDAKLIVVVTHSGATALALSKLRTHVPIVAVSDLPTVSRQMCLYWGVTPL------ENVPTNDSDQLIKHIETWGRTTGMLSPGDHIVVVSGIGLVASGHNMLVVHEV 480
140 0.000e+00UniRef50_A0A2D9VFT6 Pyruvate kinase n=5 Tax=Bacteria TaxID=2 RepID=A0A2D9VFT6_9BACT  ali  33  7...................RTKIVATIGPSWFSKSMIEKMIIAGVNVVRINMSHYNSDFNLPIIKQIRRVS-KNQNKSIAILMDLPGPKIRT---ANNDIIAIKRGKEYTL---------GVEADISINTPLKYNKISDNAKVKIDDGKLSFKVVKKITASKIRIKALNSGKIYTRKGVNISGLDIGLPSISKKDLKYIKLAAELDIDWIALSFVQSKLDRDPVDKLFKRLKKNIPLIAKIEKPEAVENIDSIIEAFDGILIARGDLGLEMELEKVPSLQKKIIKKCNEKCKPVITATQMLESMIKSPLPTRAEVNDVAGAIYDGSDAIMLSGETAIGKFPLESIRMMKSITTNVEKEIMKNDGFSRLIR-TPEKNNPKKSICYSAFQMSEDLSIKVMVVMTESGNTGNTLSSFRPSSIIIAMTPRENVYRRLSLSWGIFPVKVKKFRS------TDQMLDFNKKFLIDNNIIKKDDMFVMTAGVPVGVGTTNMIKIERV 469
141 0.000e+00UniRef50_A0A2M7XFX0 Pyruvate kinase n=6 Tax=Candidatus Uhrbacteria TaxID=1752732 RepID=A0A2M7XFX0_9BACT  ali  34  5..............APLHTRTKIICTIGPSCDSLSALRDLIQSGMSLARLNFSHNTHAYHSSLISRIRQISKQ-EQMPVGIIQDLQGPKIRLGKLPEEG-VFIHEHEEIILDAEQKIYDFKKPLVFPVSYKQLYKDVSKADQVFIDDGMIEAQVVDV-KGKKIFLEVKNGGMLFSHKGFNFPKTHLSISSLTDKDKKDLRLGLQKGVDFIALSFVTSPKDILDLRRLIKKLVRPPKIIAKIEKHEAIEAFDQILDVTDAVMIARGDLGMEIPIEMVPIKQKQIIEKCRQAGKPVIVATQMLDSMIRSPRPTRAEVSDVANAVIDHTDAVMLSGETATGKYPLKATGMMARVIQETEASRFDNVCF-SFDSCTKESIPPDISLCHLFQKISNEGQVDAILSATFLTSLSEYLNIFRPEIPLFIASDTQGSVAQLNLRWGVFSFLLKSTNISLFT-------KHALNELQKKGWVKKGMRLAVV.................. 465
142 0.000e+00UniRef50_A0A2N2ER32 Pyruvate kinase n=10 Tax=unclassified Elusimicrobia TaxID=1797919 RepID=A0A2N2ER32_9BACT  ali  33  12................TFRRTKIICTIGPASENPECIRELIREGMNVARINFSHCKYDEALKRVAMLREARAE-ARVPLALMLDTKGPEVR--MFGYSKPVVLTAGERLFVAPEAAAEFPPEKRHFYTNLPRIDKLVQVGTRVLLQDGFIETEVTELHRG-AVTVRVLNDGRLKDKAHLAVPGADYPIPFMSEKDRKDIAFAVENRFEYIALSFVRTAADIADVRELVRSADSPIKLIAKIEDKKALANIYDIIRDSDGIMVARGDLGIEVPIEELPGLQKNIIKRCYLAGKPVIVATQMLESMTDKPYPTRAEVTDTANAVMDLTSAVMLSGETANGAHPARVVNMMARIIDKTESSIDY-HTMARVTHDYVDRDNITNIMAYSVVETAHDWNAKAVAVITASGIGAQALSKFRPGVPIYAFTHHESLCHQLSLNWGVTPFLIGNPDGQLFS----EVARSTMDELRASGLVSNGDRLVYMASSPLGKRPTNTIRCEVV 494
143 0.000e+00UniRef50_A0A292QKI3 Pyruvate kinase n=14 Tax=Bacteria TaxID=2 RepID=A0A292QKI3_9BACT  ali  35  7....................TKIVSTLGPASNSEDMIRKLYRAGVTMFRLNSSHGDMETHKQTLDFIRKVEKE-EHTVIPVLLDLQGPKIRVGKF--DEPIAIKAGEVLKFRHQDKYEN----DIIPVDYEGIANDVKPGDKILIDDGKIQLTV-EKSEDNIVYAKVLTTGVIKPRKGLNLPGGTASLNILTERDKMFLEFAMNNDIDYLGLSFVRCKEDLQSLRAILDKNNSRLRIISKIEKPQALENIDDIIEYSDGIMVARGDLGIETPIQQLPIVQKTIIRKTNAVRKPVIVATQMLESMIENPMPTRAEASDVANAIIDGADAVMLSGETAAGKYPVEAVSIMKKIAEDINNSQFMRKN-EFPSTIRTEENAIPMSIAVSVADTLKNPKAKGVIALTATGYTTALISECRPSVPIYSFCEDAKVGRFMQLFNSVSSIKVDDKNIEIDKSSLIEL----NEFLKKELGMEAGDCVIITGSVPMSGQSTNFMKIHKI 476
144 0.000e+00UniRef50_C1DFR2 Pyruvate kinase n=28 Tax=Gammaproteobacteria TaxID=1236 RepID=C1DFR2_AZOVD  ali  33  3..................RRTKIVATLGPATETPEAIEGLVKAGVDVVRLNFSHGKAEEHQARAARVREMAAKH-GRFVAILADLQGPKIRISRFADGK-VLLEKGQTFVLDA-ALDKNAGDATRVGIDYEALITDSRPGDILLLDDGRVVLETREV-KASELVCAVLVGGPLSNNKGINRQGGGLSASALTDKDCADIKTAAAMQVDYLAVSFPRDAADMQHARRLMQEAGGNAGLVAKIERAEAVQVLDGIILASEAVMVARGDLGVEIGDAELVGVQKRIIERARVLNRAVITATQMMETMITQSLPTRAEVFDVANAVLDGTDAVMLSAETAAGAYPVETVEAMGRIILGAEQ---HPLAHRSKHRMDQVFHRIDETIALSAMYAANHEGVKAIVCLTESGDTPRLMSRIRSHLPIYAFSRHPRTQSRVALFRGVHPIPFEADRIAEA-----ELNARAVKELLQRRLVAEGDLVLITKGAGHAQGGTDTLRIVRV 476
145 0.000e+00UniRef50_A0A0D6DY92 Pyruvate kinase n=17 Tax=Lactococcus TaxID=1357 RepID=A0A0D6DY92_9LACT  ali  35  3..................KRVKIVATLGPAVESAQKIAQLIKEGANVFRFNFSHGDHEEQGDRMNVVRRA-EEIANQKVGFLLDTKGPEIRTELFEGEKEFEYNTGDLLRVAT--QQGLKSTKDVIALNVAGIFDNVEIGQTILIDDGKLGLTVAGKDAATRFEVEVQNDGVIAKQKGVNIPNTKIPFPALADRDNADIRFGLEQGLNFIAISFVRSAKDVNEVRAILEETGNHVQLFPKIENQQGIDNIDEIIAASEGIMIARGDMGIEVPFEMVPVYQKQIIQKVNAAGKAVITATNMLETMTDKPRATRSEISDVFNAVIDGTDATMLSGESANGKYPVESVRTMATVDKNAQALL---KEYGRLSTDKFDRSNVTEVMASAVKDATNSMEIKLIVALTESGSTARLISKYRPDADILAITWDEKVQKSLMINWGVIPILNEKPAS------TDDMFEVAEKAAIESGLVESGDNIIIVAGVPVGSGRTNTMRIRTV 499
146 0.000e+00UniRef50_A0A2V2N928 Pyruvate kinase n=1 Tax=Methanospirillum lacunae TaxID=668570 RepID=A0A2V2N928_9EURY  ali  34  172..........DTPSGPGVRLTRIIATIGPASADIETISNMIRAGMDIARLNLSHGSLEQHQATMTMIRHVARDL-GRQVAVMIDIPGPKLRVRSLP-ESDRDLSLHEKVILSADPH------NDEIGIGPADYIPVVCEGDAILLADGAVLLRVTCVGEN--ICAEVVSGGSIRMGAGVVIPGRRPDIPYANDELVKNLSFAAELNPDFVALSFVGSAGDIIVVRSILSEKQVQIPLIAKIETKNAVDLFDEILAAADGIMVARGDLGVELPIACVPYVQKEIIRSCNKAGKPVITATEMLESMVEHGRPTRAEVADVANAIADGTDATMLSAETSIGKDPARAVRMMAEIACETERHLPYHKILDE--RRLWHETGPSGIISYSACYLANELESRAIVAFTRSGITAERVSRCRPGNPILAITPDEQIARRLLIRWGVIPCIHTPIHTA------DELFFIALELAKERDLITSGDRLIIIAGNFAGVGRTNMIKVQNV 644
147 0.000e+00UniRef50_A0A1U9NKD6 Pyruvate kinase n=4 Tax=Planctomycetes TaxID=203682 RepID=A0A1U9NKD6_9BACT  ali  31  4...................KTKIIATLGPACADENTITELVEQGVDMFRLNFSHGTLEEHAEMLSHVNRARANFP-FSIGILADLCGPKIRITELPAGESVS--SGDTVRIVS---KLPRGTAARFGTNYPDFYSDVSIGQRVLIDDGQIELKITDKQNG-EVICEVITGGDLKSRKGINLPDTDISTPAITERDWQCVNWAMDHGVDYLALSFVQSSDEITWLKNYLIEKGSLIRVVAKIEKPQAVENLQSIVNASDAVLVARGDLGVEMDLARVPLIQKQITRLCRKLGKPVIVATQMLQSMIKSPTATRAEVSDVANAIMDFTDAVMLSGETAVGEYPVKAIQTIEQIGEVTEAWLDSLNEPR-PRIETHSDLSIDESIARSVAQIVDDMKAKMVVVWCQTGCTARLLSKARIDVPILALCADREMCREMSLHYGVIPVCRTRPRDFSQFADL------ANKVAQDNGWAKKDDTIILLTGCLLRPNSTKAIVFHTV 471
148 0.000e+00UniRef50_B4R000 Pyruvate kinase (Fragment) n=43 Tax=root TaxID=1 RepID=B4R000_DROSI  ali  48  67.SQLDYQSRLQYQAPASIPLSSIICTIGPSSNSPEKLMELIRAGMRVVRMNFSHGSHEYHCQTIQAARKAIAMYVERTVAIALDTKGPEIRTGKLAGGAEIELKTGGKVTLSTKKELADKSTQENIYVDYQRLPELVKPGNRIFVDDGLIALIVKE-AKGDEVICQVENGGKLGSHKGINLPGVPVDLPSVTEKDKQDLKFGAEQKVDIIFASFIRDANALKEIRQILGPAGACIKIISKIENHQGLINIDDIIRESDGIMVARGDMGIEIPTEDVPLAQKSIVAKCNKVGKPVICATQMMESMTNKPRPTRAEASDVANAIFDGSDAVMLSGETAKGKYPVECVQCMARICAKVEAVLWYESLQNSL.................................................................................................................................... 441
149 0.000e+00UniRef50_A0A2J6I7M0 Pyruvate kinase n=7 Tax=Bacteroidetes TaxID=976 RepID=A0A2J6I7M0_9BACT  ali  31  1...........MKKNTNFLMTKIIATLGPATDSIEKILELIEAGVRVFRINFSHGSFNDYDKLIVNIRNA-EDRSGQFVGILGDLSGPKIRVGKVIPEG-VILKNGQEIKFVKKEIIGGSGFEYSFSTTYPQFIDEVKIGERILLDDGNIQLKCNEKGEDAFLLCEVVEGNLLTTAKGINLPDSELSLPSLTEKDYECLDYAIKKSVDYLALSFVRSGEDIRHLKEKMKQANARIPIISKIEKPQAIDNLEEILEESDGIMVARGDLGVEMDLAEVALLQKKIINMCRHHMKPVIVATQMLQSMIDNPVPTRAEVSDVANAIMDGADAVMLSGETAVGNYPVHAVKMMARVADKTQKYQVEQFGSKGNFMPYEGLLSRKAAMARGVAMMAKDMKAKFIVTWTHSGGSSVFLSQQKLQIPIIACGENKKRLQQMSILYSIMPLFMKQPKSGS------KFIAAVNQMILNNEWAKEGDPIIIVASSPIRRGVTNRVILHYV 507
150 0.000e+00UniRef50_A0L7K0 Pyruvate kinase n=2 Tax=Bacteria TaxID=2 RepID=A0L7K0_MAGMM  ali  34  3..................RRAKIVATLGPACSSVEQITRLIEAGLDVARLNMSHGDHKAHLELIHNVREAS-RIAKREVALLCDLQGPKIRVGHL--DEPLRLEKGQQWAIIPEGSHPPKLKDGIIPCTYAGLAKDAVPGCRILFDDGYLQARAIGTEEG-ALLVNIEHGGLLKSHKGINMPDASISAPSLTTKDQQDLFFGVKHDVDYVALSFVRSAKCVQNVKFMLHRRKIYKPIIAKIERPEAIRNIDEIIKVVDGIMIARGDMAVEIGNHRVPSVQRQIIQKCRAKGKPVITATQMLESMIQNPSPTRAEASDVANAIWDGTDAVMLSAETSVGVDPINTVLTMGRIVEEAERNPR-------GPRLDAESHSISSASMMAAARVAEQVSARWIIALTVTGSSALSLARFRPEVPVLGAARTQGGVRRMNLYWGITPRLF-----NYSIEEREDIEPEVIQWMREQSMLQVGEKIVVVGGLLSNHSTSSSIRV... 468
151 0.000e+00UniRef50_L8GIR3 Pyruvate kinase n=1 Tax=Acanthamoeba castellanii str. Neff TaxID=1257118 RepID=L8GIR3_ACACA  ali  34  30......LSDLGAFPPTTM-KTKIVCTLGPASSSEEVLRELILAGMDMVRLNFSHGTHEEMEAIFSTVRRISSEFSEQ-VSILCDIQGPKIRTGKVK--EAFNVDVGDHIDVTADSVL---GTPECVQIKYPHMMEDLDVGDKIFINDGIVKLRVEAK-KARSLACVVEAGGQISDHKGCNIPKGKLSLNIITEKDKKDLELIAKLNPEYVAASFIGNGADVEKVRSCLRDFGNDVKIMAKVERPGALDCIDEIISASDAIMVARGDLGVEIPTWGVPAAQKDIVRKCNREGKPVIVATQMLESMTLAQRPTRAEASDVFNAVLDGADAVMLSGETSVGKFPVICVKTMDSIVGEAERFMESRNPDHYDSANPGN----AELMGHGCFTMAKQFNAQGIVTIATTGYSTRMVSKYRPNIPILAFTANLRAARELNVVWGVQSIYSPLVTG----DSVEEKARNAIKMGLDLDLIDKNDHVIVVASSHLAPSS......... 503
152 0.000e+00UniRef50_G2QJT9 Pyruvate kinase (Fragment) n=2 Tax=Chaetomiaceae TaxID=35718 RepID=G2QJT9_MYCTT  ali  63  1..............................................................................................................................YIDYKNITKVIEPGRIIYVDDGVLAFEVLEVVDDKNIKARARNNGFISSRKGVNLPNTDVDLPALSEKDKADLRFGVKNNVDMIFASFIRRAQDIRDIREVLGEEGRHIQIIAKIENRQGLNNFPEILAETDGVMVARGDLGIEIPAAEVFAAQKKIIAMCNIAGKPVICATQMLESMIKNPRPTRAEISDVGNAVTDGADCVMLSGETAKGNYPYEAVREMSLACLKAENSIPYVSHFEELCTLVKRPVSIVESCAMAAVRASLDLNASAIFVLSTSGESARLISKYRPVCPIIMITRNPSSSRYAHLYRGVYPFLFPESKPDNWQEDVDRRIKWGLHHAIDLGILTEGETVVVVQGWKGGMGNTNTLRIVK. 377
153 0.000e+00UniRef50_A0A2M8LGX2 Pyruvate kinase n=5 Tax=Candidatus Uhrbacteria TaxID=1752732 RepID=A0A2M8LGX2_9BACT  ali  35  3..................KRTKIICTIGPASASPSVLEKMMRAGMDVARLNFSHATHADHKRLIRTVRSASKK-AGKFVPLIGDLQGPKIRLGELPKEG-VELPQGGTMIISTNADRYQEG---VLPVTYKNLHLDVKKGDRILIDDGIFELNVLRV-SGYRIHTKVVNGGRITSHKGMNFPDSQLHVSSITTKDKADAVFGVEQGVEWIALSFVTGPAPVLAMKRLIKKHTPPARVIVKIEKHEAIDRFEEILAVTDAIMIARGDLGVEIPAEEVPIRQKEIIEKCRQAGKPVVVATQMMDSMIRNPRPTRAEVSDVANAVFDHTDAVMLSGESATGKYPLQTVKMMAKIAQEAEAST-----YDDVKLSMDHDRDLVSASSLAVKLLALRGSIDGVLVSHILAPWSETILKSRPEVPLFLAVGSDRQARQLAMGWGAQPFVMKTQNERTF-------VRTAIAKLTKDHLIKKGMRLAIVLGERHGEGF-DLVEVR.. 467
154 0.000e+00UniRef50_F0IGR0 Pyruvate kinase n=623 Tax=root TaxID=1 RepID=F0IGR0_9FLAO  ali  34  5..................KKTKIVATLGPATDSPEILKQMILAGVNVFRINFSHANYEEVKQRIQQVRAIEEEL-NTHVALLGDLQGPKLRVGVMEEGVVVE--KGDQISFITGEPFV--GNKERAYMNYTQFPCDVKAGERVLLDDGKLIFEVLSTNEKDTVVAKVLQGGVLKSKKGVNLPNTNISLPALTEKDIKDAIFAIEQEVDWIALSFVRHAKDIEDLKMLIKEHTTNIPIIAKIEKPEALANIDEIIANCQGLMVARGDLAVETPAQEVPLRQKELVRKAKEARIPVIIATQMMETMIESLTPTRAEVNDVANSIIDGADAVMLSAETSTGKYPVQVIEKMSDIINSVENSEFIKVPRISPIREG-NERFVTQSICLSAAKLADEMDAKVISTLTGSGYTAFQVSALRPNAHILVFTSNKRLLSKLSLLWGVTTYYYDRYVS------TDETIEDINRIATREGHVKVGDIVISLSAMPIYQGRVNTVRATQI 476
155 0.000e+00UniRef50_V5SFZ2 Pyruvate kinase n=6 Tax=Alphaproteobacteria TaxID=28211 RepID=V5SFZ2_9RHIZ  ali  30  5..................RRVKIVATLGPASSAPDVIERLFVAGVDVFRVNMSHTGHDAARGLVRTIRDVSDKHR-CSIGVLCDLQGPKFRLGEFVDGRTL-VKAGELFRF---DQSGEPGTSQRVSLPHAPIFDAVKPGDALLIDDGKLRMRVIESGKG-DIVAEVVTGGIMSNRKGLSLPDTVLAVSPLTEKDREDLDLALKVGADWIALSFVQRAEDVIEAKRIID---GRAAVLAKIEKPSAIDEIDDIIAAGDGFMVARGDLGVEMPVERVPGLQKKITRKARSAGKPIVVATQMLESMTTSPMPTRAEVSDVATAVFDGADAIMLSGESAVGQYPVETIQMMNRIAREVEHDPSYDTLVHAIDLPPVPTGADAIA--VAAHAISDTVKVAAILCYTATGSTALRVARERPNLPVIGLTPIARTAQRLTLVWGIETVLTGD------PEDLADMVRKATRIAYEGNFVKPGQGVVITCGVPLGPGATNMIRLAFV 470
156 0.000e+00UniRef50_F8IA98 Pyruvate kinase n=2 Tax=Sulfobacillus acidophilus TaxID=53633 RepID=F8IA98_SULAT  ali  40  1.......................MATIGPATRSFDRLAALAEAGMDVARINLSHGDVETHRETIRQIR-AVETQTGRPLAIMLDTAGPEIRITT--DAAGLTLVPGQRVRVGTQAA--------DIQVDEPRILTQLTAGTRLILDDGNIVLRILATGDP--LEAEVLIGGRLMNRKKMISPDRPWDLDILTKEDRVALAMGVEEGVDWIAASFVRSPDDIIAIRRELEDHGRLIPIMAKIENVQAVEAIEAIVTVADGVMVARGDLGIELPVEEVPWLQKKIIAAANRAGKPVVTATQMLESMIAHPRPTRAEVTDVAHAIMDGTDAVMLSAETASGDYPVEAVRVMAQVAEAADQQAEHFRRY-------LTRGSITEAVSHASVTAAEDLQARAILSATESGSTALAVAALRPRVPIIALTPYLPIARRLAIVWGVVPVVTARAHS------TDQMMDNAVTTALAHGWVASGDRVVLTAGVPIGQGTTNLMRVITI 452
157 0.000e+00UniRef50_A0A2E7N7Q6 Pyruvate kinase n=2 Tax=cellular organisms TaxID=131567 RepID=A0A2E7N7Q6_9BACT  ali  36  1.................MRKTKIIATIGPKTESEEMIKKLSDGGMNIARINMSHSDHKQXSGIINRIKKVSQE-AIFPIGIMVDTQGPEIRTSS----QEFRLEEGDNFKIAVSSACDIQEGEKHTFVNYQNLIKKVKEHDVILVDEGLIALEVLKI-EPYHVTCXVLNKGNLGKRKSINLPGIKTDLPPITEKDIKDVRVAVENDVDFIAQSFIRKRKDIKEMRDVLNKLNSNAMIIAKIEDQEGIDNMEEIIDEADGIIVARGDLGVEIPFEEIPIVQKNIVRKCIEVGKPVIIATHLLESMIENPRPTRAEVTDVANAVFEKADCIMLSGETTKGSYPVECVKTMSNIVKNV------QSRLKFEVSNGIKTKNVKEAITLGACINAENLDAKSIIVFSKTGKLLNLVTKKRPNIDIFAFTDNERTRRKLMIYWNVFPFKI------NFDDNFNTMVNNAIDILKKNNFLLNKDRVIIVSDVNPRK-NVDILEIREI 464
158 0.000e+00UniRef50_A0A1Z8UZW9 Pyruvate kinase n=2 Tax=SAR116 cluster TaxID=62654 RepID=A0A1Z8UZW9_9PROT  ali  34  8....................TRILATLGPASNSREMIKTLAEQGASAFRLNFSHGTQDVHKATYQHIRDVAEEL-DHPITILADLQGPKLRISTVKEGT--ELTAGXEFVF---DDQDKIGDQNRVYLPHPEIFDAILPGHRMLVNDGNLKFTVTRVETGK-IITKVXAGGPISDRKGVNVPDVSLKISPLTEKDLADLEFALGLGVDWVALSFVQHVTDVVEARSIVKDRAAX---MVKVEKPAALQELDDLIRACDGIMVARGDLGVELPPETVPGIQKEITYACRRIGKPVIVATQMLESMITHHTPTRAEASDVATAVTSGVDCVMLSAETAAGQYPSESVAMMRRIIETTEARKGYA---SSLALNPVDAHNTYHAVASSATQLASGIGAVCIVGFSKTGTTGIRLSRERPDLPIYLITPSQIARQRLGFTWGITSIL------SPHFDSFDDALTEISSLLLTNTDCQSGDTVVVVAGTPXGAGSTNTIR.... 465
159 0.000e+00UniRef50_A0A1G0YIF7 Pyruvate kinase n=2 Tax=unclassified Lentisphaerae (miscellaneous) TaxID=641407 RepID=A0A1G0YIF7_9BACT  ali  35  1.................MKKAKIIATIGPACENPSMIRKIAEAGVDVCRLNFSYGTHDEHMKRIEMIRKISAD-TGKSIAIMQDLQGPKIRVGKLKN--PVTVRRGDILTLTGKSEHK---SEFCLPTTYKGIANDAEKGKTILLADGKIILQVIDVDKAKQIKCKVLSGGTILTGKGINLPYTKISLPALTPKDESDAVFGARAGVDYMAISFVRKADDVLKLRRLLKRENANIPIIAKIEKPEALDNIDEILDVVDGIMVARGDLAVEISFAKVPVAQKAIIHAANKKGKITIVATEMLGSMVDNPLPSRAEVSDVANSILDGTDAVMLSNETATGKDPVNAVKAMAEIVIETEKLFGKEAFHREL--NLPETHKLGEAMCSAAAFLSYSLSEKALAVLTSTGETARILSKYRPESVIYAATCCDVVFHKMALFHNVLPIKLNKKTSKK-DEDVHLSFSLLEKEILKRKLAKPGERLLVLAGISHPESKTNSINVR.. 476
160 0.000e+00UniRef50_A0A1I4U2M1 Pyruvate kinase n=1 Tax=Methanolobus profundi TaxID=487685 RepID=A0A1I4U2M1_9EURY  ali  35  7...................KTKIVCTIGPASSSEDVLRRLILAGMDVARLNFSHGDLDDHRIMIKRIRKIAKEL-NKVVAIMADLPGPKIRVGIIENE-PMMLERGSHVVLTTRDV---KGADSVIPVQYKQITESVTEGSPIYLNDGFIQLDCKSVV-DEDIHCDVVVGGPLFSKKGLNLPGSKILVNPITGRDLEIVDFGLQEGLSIFCLSFIESREDVIQVRNYAASQGKDVFIVSKIERDNAVKNINEILKESDAIMIARGDLGVEIPIQHVPIVQKDIIHKANLMSTPVITATQMLESMTGNIRPTRAEATDVANAIIDGTDAVMLSAETAVGKYPVETVQMMAMIAHSTEKWRDHTTIGLEMMKKAIQRMHPTDMISIQVNDALRSLPVHFVITPTVSGETPRHISRFRPDVWVLAFSRYPLTCEQLAMQYAVHPVLASEK-----VDDWEEM---TMDLLETSNMIESGDLLILTQGQVSGPGGTNLLKFIEV 478
161 0.000e+00UniRef50_A0A2W7IFK2 Pyruvate kinase n=2 Tax=Humitalea rosea TaxID=990373 RepID=A0A2W7IFK2_9PROT  ali  35  89....................TKIIATLGPASSTVEQITKLFHLGADVFRLNFSHGSHEDHAERIRIIRGIEARM-GRPIGILADVQGPKLRVGKFQAGR-VQLQAGQHFRLDLSP---TPGDVRRVQLPHPEILAAAGIGTHLLLDDGKLKLRVLRQRDDH-LETEVVLGGPLSDRKGVNVPDVALPIPALTAKDRADLDFVLPLGVEYIGLSFVQRAEDVAEAKAIC---NGRAWVMVKMEKPQAVENLDAILALTDCVMVARGDLGVEMPTEDVPLIQKRIVRAARALGKPVVVATQMLESMISAPSPTRAEASDVATAVFDGADAVMLSAETAAGQYPYEAVSIMDRIVARVEQDSDWRRITDAARPAPERNSAGAIA--AAARQVAHTIEAKAIATFSATGSTTLRVARERPDCPILGLTTSVETSRRMAVIWGVHPVMTPEAHS------MTDMVSKAIRATVTEGFAKQGDEVVVTAGVPFGPGTTNALRVATV 552
162 0.000e+00UniRef50_A0A2H6HEI6 Pyruvate kinase n=3 Tax=Bacteria TaxID=2 RepID=A0A2H6HEI6_9BACT  ali  33  3..................RKTKIIATLGPAVASFEGVCGLVEAGMNVARLNFSHGTHESHAQMVSWVRDAADRFE-LPIAILQDIQGPRIRVGSFAGGA-IELTDGDVVHLEPGADEMSGSTIFVENLQHVTLTE----GSQIRMSDGLIGLEVTAV-DGSRVTARVIEGGAVADHKGVAFPGAPMTVPAVTWKDEADLAFGQEQDVDYVAASFVSSGGDIRDVRRLI---GADTPIIAKIESAIGYENLDDILDEAYGTMVARGDLGVELSFESVPRAQKDILARSNARARLTITATEMLESMTHASRPTRAEVTDVFGAVLDGSDAVMLSAETAVGKYPQRTVAAMDRICREAEASSQYGKTAD--LELDSDDARFAVATAQACVEAADSLGLHAIVAFTESGSTSRLISKFRPRADIYAYTPNLRTYRRMALYAGVRS------GQFRRVNSTDEMIIYAEKQLLDEGIVQRGDGVVMAAGIPPNAASTNLMKLHSI 467
163 0.000e+00UniRef50_Q0S7A1 Pyruvate kinase n=32 Tax=Actinobacteria TaxID=201174 RepID=Q0S7A1_RHOJR  ali  33  1............................................MDIARLNFSHGDHTDHEANYRRVR-AAADNTGRAVGILADLQGPKIRLGRFADGAAV-WTAGEQVRITVEEC---EGTHDRVSTTYTHLAQDARPGDRLLVDDGKIALTVIDI-DGNDVVCRVTEGGPISNNKGVSLPGMNVSVPALSGKDIDDLEFALRLGVDLIALSFVRAPTDIDRVHEVMDRIGRRVPVIAKIEKPEAVDDIEAIVRAFDAVMVARGDLGVEVPLEHVPLVQKRIVQIARENARPVIVATQMLESMIDNSRPTRAEASDVANAVLDGADAVMLSGETSVGAYPIETVATMARILSAVE------HQSTTVPDLTHIPRTHGGVLSFAARDIGERLNATALVAFTQSGDTARRLARLHTPLPLLAFTPVPQVRNELALTWGTETFLVDPVAS------TDEMIRQVDTALLRLGRYQRGDLVVIVAGSPPHVGSTNLIHVHRI 439
164 0.000e+00UniRef50_A0A254WQZ9 Pyruvate kinase n=1 Tax=cyanobacterium TDX16 TaxID=1503470 RepID=A0A254WQZ9_9CYAN  ali  32  1.................MIRTKIIATIGPASESMQALGDLLDAGVDVFRLNFSHGTLQQHEMTYDRIRSICRQR-GVAAAVMADLCGPKIRVDPVEEDA-FEIRKDDEIDIVGGHIV---GNASRISTNRPELVREVAVDHRVLIDDGLVRLRVISASADR-LRCVCEVGGLISTRKGVNLPDSDLEMSALTQKDREDLAWAVEHGVDYIAMSFVRRAADLRELRDLLPLAEDRCRVVAKVETPLAIQHIDEIIESADVVLVARGDLGVELDLARVPLLQKQIARKCRLAGRPVIIATQMLQSMVECPTATRAEVSDVANAILDAADAIMLSAETSVGSYPIESVKMMVRIAEQTEDFLDRSGAASAEVNSLVP--RVPTAVAHGANLLARELDAKLVAVWTQTGNTARLLSKCRLPSVVIGLSPDEHVCRRMAMYYGIEPVQMSR------DEDVLAMLGEVDAALLSRGLAVSGDMIVVVAGTRLHVGSTNAIFIHLV 470
165 0.000e+00UniRef50_A0A2N2JM96 Pyruvate kinase n=2 Tax=Bacteria TaxID=2 RepID=A0A2N2JM96_9DELT  ali  36  1.................MRRAKIVCTLGPATNDQTTIDALVAAGMDCARLNFSHGTHESHARAAAMV-RAAASRAGRPLAILADLCGPKMRVGVFPGG-PVELVAGARFTLKTRDA---PGDVNGVGVSYAALAEDVRIGDAILLDDGLLRLRVDSVVDG-DVHCTVEVGGALSDKKGLNIPGTPLSTPAVTEKDKEDLVFAVELKVEFVALSFVRRAADVLEARALAGD----TPIIAKIEKPEAIANLDAILDAADGAMVARGDLGVEMGAEKVPLLQKRIIRAVNHRGKIVITATQMLDSMIRNPTPTRAEAADVANAVIDGTDALMLSGETAAGKHPLLAVAMMDKIVREVEDDWQRERKSDGFHAELGSDWGFADGAAKAAAVLSFALPMKALVVFTRDGRTARMLSEYRPRAPIVAMTQESGVANQLALEWGVIPRV------EVPPEIMSETIRIATGLLLREGICQVGDEFTLVMGWPPSSG-TNTLKLHRI 470
166 0.000e+00UniRef50_A0A1E7FFD8 Pyruvate kinase n=4 Tax=Bacillariophyta TaxID=2836 RepID=A0A1E7FFD8_9STRA  ali  33  69..................KSTKQLATLGPSSGDKEMIEKLFLAGADCFRLNFSHGSQEQKKELLIIIREIEEKYS-HPIGILGDLQGPKLRVGEFSNPEGEKLAVGQTFRLDLDTAL---GDSTRVNLPHPEIIGASEVGHELMVDDGKVKLTVTEKGDD-YLICNVDVPGKISNRKGVNTPDSILEISPLTPKDRSDLDYMLEIGVDWIALSFVQKPEDILEIREIIDRKQSKPAVMAKIEKPSCFDNLEKLVELCDGIMVARGDLGVECPPEDVPILQKTIIDECRKQGKPVVVATQMLESMIESPTPTRAEASDVATAIYDGADAIMLSAESAAGLYPEESVAMQQRIINRVEEDAHYRNYLDA--NILEHDNTPTDAVIVAAKQISKTIAAKAMVCFSLTGSTARRASKNRPNVPIMVMSPFVEVTRQLAMSWGVYPFDYENPIVEKATDDLDLVLRNACRSALKKGLVDPDDLLVVTAGLPFGTGGT........ 561
167 0.000e+00UniRef50_A0A238DVV9 Pyruvate kinase n=218 Tax=root TaxID=1 RepID=A0A238DVV9_9BURK  ali  32  53............HSHSMTRATKIVATIGPASASPEVLERIIRAGVDVVRLNFSHGNAQDHIDRAVLVRDTAKRC-GREVAIMADLQGPKIRVGKFAGGK-ILLEKGNRFTLDAE---CELGNADIAGLDYKDLPSDVKQGDRLLLNDGLIVLAVDAV-EGSKIITTVVIGGELSNNKGINKQGGGLSAPALAAKDMEDIRTAMAFQADYLAVSFPKSATDMELARQLANAHGHKPALIAKIERAEAIPALAEILKASDGIMVARGDLAVEVGNAAVPALQKRMIRMARDMDRVVITATQMMESMITNAVPTRAEVSDVANAVLDGTDAVMLSAETAAGKYPVETVEAMASICVEAERFEEMKLERDFV---DKSFTRIDHSIAMAALFTAHHLDCKAIVALTESGSTALWMSRHRVRMPIYALSPKVSSVRRMTLYRNVRPVHM------QFSNDRDEALKQAEILLVKNHALAIGDSYAITCGEPMGPGGTNMLKLMRV 530
168 0.000e+00UniRef50_A0A2G9ZCN7 Pyruvate kinase n=3 Tax=unclassified Bacteria TaxID=2323 RepID=A0A2G9ZCN7_9BACT  ali  40  3..................KMTKIIATLGPASDSYETICELIKSGVNIFRLNFSHDSXXX-XXXXXXXXXXXXXXXXXXXXXXXXXQGPKIRVGEI-DENGIKLENGAEVILTVNAQ-----SEGKIEVQYKGLDKDVSAGDVVLLDDGLLELKVLEV-SGGDIKCEVIVGGILKSKKGINLLTSSISIPAISEKDESDAKFGCENEVDFVALSFVKNAQDIKDLRKIIGENGS--QIIAKIERHEAVQNVREIVEEADSIMVARGDLGVELGMDKVPVLQKRIINECLRQNKPVIVATQMLESMTKNPRPTRAEASDVANAILDGADAVMLSAETAVGDYPLEAVKTICNIATDVEAWVIENQVVIG-KRIQSEVDSVAEAISNTVVRLAKQTGAKLILVPTATGITANLISNRRPFVQVLAITHDHKAMRRMAILWGVQARVVE-------YNTVEEMIVNGIEIAKKYDYIKKDDRVIIASGLPGVPGGTNIVEVMTV 467
169 0.000e+00UniRef50_A0A2D5NJG4 Pyruvate kinase n=3 Tax=Planctomycetes bacterium TaxID=2026780 RepID=A0A2D5NJG4_9BACT  ali  35  4.................HNRTKIVATIGPASHTEETIEELVRVGVDVFRVNCAHASHDSIRRMVRRIRRVAKRL-DAPIGILADLQGPKIRVGKLKNAEPIYLKRGMQVVIDCTPDVIGEARSDVIGTGYERLAKDVSKSERILLDDGNLELKVTGV-SGRRITTKVVYGGMLIQSKGINLPGTKVSASCLSAKDLADLEVAIDAEVDFIALSFVREASDVHELRRHIQRRKGDVSIISKIERPEAVKNLPAILDATDAVMVARGDMGVEMGPEVVPQVQKRIIELCNRANKPVITATQMLETMISNPRPTRAEASDVANAIYDGTSAVMLSGETASGKYPVRTVRTMEKIVRSAEK---QAVAMQDRRRQLSSHITPTEATVRAAAHAAFNTGARLIACYTETGSTSMQLAAERPPTHIVGFTPSRRTVQRMALVWGVIPRKVRPGRTSH------ALTIDGDRIMREEGLVKPGDHIVQIAGTVRQAGLTNTMSIRT. 477
170 0.000e+00UniRef50_A0A1F7TCS1 Pyruvate kinase n=2 Tax=unclassified Candidatus Tectomicrobia TaxID=1802341 RepID=A0A1F7TCS1_9BACT  ali  34  1.................MPRTKIVCTLGPASRHTFTLRSMIRAGMNVARLNFSHGTHTEHRATIRKLRRLSGE-EGRPVAVLADLAGPKFRLGKVREGE--VLREGRRVRIVSHPIL---GTAERLSLNRPELIPQLVKGHRLMIWDGKLQLEVV-TPGPEEALCRVIVGGSLKDNAGVNLPDTSLDIPSLTEKDLLDIAFGVKEGVDFFGFSFVRTKADVELCRKEITARNGATPIIAKMEMREAVENMEEIIEAADGVMVARGDLGIETPLEKVPMVQKRMIASANLHGKPVITATEMLLSMVTAARPTRAEAGDVANAILDGTDAVMLSEETATGRNPAAVIRTMARIAEVTEEGMFASSTRRMRRSDLRDRGIAHAIAHTAAV-LAEDLDAALIVCPTDSGDTPRRVALHRPRQPVLALSVSEHTVRRLALSWGVIPWKIARRVPP------DQIVAELRKRIAEEKLGQAGDYIILTAGFPFG............ 457
171 0.000e+00UniRef50_A0A1F6QUN2 Pyruvate kinase n=5 Tax=root TaxID=1 RepID=A0A1F6QUN2_9BACT  ali  36  2...............SQMNNTKIIATLGPVSNTEDMMIKLINSGADVFRLNTSHGNKEEHLATIKLIRKVSEKL-NQPITILLDLQGPKIRLGIIP--EIIILEAKQVITLVEDTQTT---DIAVIPVDYRGFIQAVDIGDKIFINDGKVELKVVEKTINQ-IQALVINGGEISSKKGINMPGIVTTIPAITEKDKDYIKFGIEHEVDYFALSFVRTMDDVEKAKQFIKKHKGNIPVIAKIEKPQAIENMDDIIRCADCIMVARGDLGIEILPEKVPIVQKELIHRANLANKPVIVATQMLESMITESIPTRAEANDVANAIMDGADAVMLSGETTVGKYPIQAVEMMNRIASNVEQSNMYKMASKTFLKDNLSHD----------VQLANELEVKAVIAITESGYTAQILSNSKIIPPIIAICNNIRLCRQLNLLWGVIPFMYKK----DSLEYKEQNVEEICKQLISSKIISKGDKVVFVGGLPS............. 455
172 0.000e+00UniRef50_A0A101DX94 Pyruvate kinase n=2 Tax=Euryarchaeota TaxID=28890 RepID=A0A101DX94_9EURY  ali  33  18.................MSRTKIIATLGPAS--IDRVDELVRAGVSAFRLNLSHGTHEWHTHAIQKIRALSHE-----VGIMADLPGPKLRLTHVREGT--RLERGAKVVLTHGEGV---GDEHVLYVDYPRLARDVQAGERVLIGDGDVELVVDSV-SGSDVLCTVVAGGDVASCRGVSLPSTRLGVSVPTERDREHIAFAVDAGVDLIAASFIRDEHDVRAVQREVQAHGGDVPVIAKIEKHEALEHLDAILDVAYGLMVARGDLGIEVPIERVPLIQRRLLMMCRRVAKPSIVATQMLESMLTSPTPTRAEVSDIANAILEGADALMLSGETAVGRYPVEAVRIMERVASETERS----GELEGPVELEGRGMGVQQAISHAACILAHEVGARAILTPTASGSTARHVASHRPSQSVLSISESHATLRRLSITWGVQPVHTSEFGS------LEHVLKGLMRRMRERGDVASGDLVVITAGVPIGAGGTNMIRVERV 478
173 0.000e+00UniRef50_A0A2A4U4C8 Pyruvate kinase n=4 Tax=cellular organisms TaxID=131567 RepID=A0A2A4U4C8_9GAMM  ali  34  1.................MSRTKILATLGPAT-DENVLREMIRAGLNAVRCNFSHGTQEDHAKRIQMVRRLAKS-EGSAIGVLADLQGPKIRVARF-KDKEVRLVTGDKFILDASMDLQ-AGDATKVGLTYKKLPEDVSKGDILLLDDGKITLEVTEV-SGACVTTIVKNGGKLSDNKGINKLGGGLTADALTEKDRSDIKAIGKLDVDYVAISFPRDADDVRLAIKLLKEAGSKAGLIAKIERAEALHCIDDIINASDGIMVARGDLSVEIGKEEVPGVQKTLIKRARELDKIVITATQMMESMIYNSTPTNAEVSDVANAILDGTDAVMLSAETATGNYPVKVIQAMRNICIATERHPDTRY---SEHRIAKEFQRIDEAIAMATMYAANHLNVKAILSLTESGASAVWMSRINSHLPIFAFTRHVLTHNKMTLCRGVVPIEFDSTTMPRFSVN-----QLAIDELKKRGFVQDGDLVILTSGDHMGEGGTN....... 464
174 0.000e+00UniRef50_A0A2G6LGU6 Pyruvate kinase n=4 Tax=Gammaproteobacteria bacterium TaxID=1913989 RepID=A0A2G6LGU6_9GAMM  ali  34  6..............KPRNRFAKIVATLGPASSDKQMINALFKAGVDIFRLNFSHGSHAVHQQNIQTIRQLEQEY-NHPIAILIDLQGPKFRIGRFKDEK-ITLEQGQNFVFDSDESL---GNNSRVYLPHPEVFASAKIGDRLLIDDARACFEII-KNDGKRIKTKHIYGRAISNNKGLNMPDTILNVPVLTKKDETDLKFGLMQDIDYVALSFVQQASDMAYLRTIVGDKAS---ILAKIEKPSAIDNLDNIINASDAIMLARGDLGVEFPPEKLPSIQKSVIQQARKFGKPIIVATQMLESMIESPVATRAEATDVDAAISGGADAVMLSGETAIGKYPIDAVSFMHRMIIESEKDHRYQIKMNTPQDNQPDKTSET-AISHGVKAIVNAMPICAIACFTTSGGTATRVSRERVLTPLIAMTPDISLARRLQLYWGI------DAREMTEEKKLKDIMTAAIETVENRGYGNDGDWVVVTAGVPFGAGTTNTLRLAQV 476
175 0.000e+00UniRef50_A0A223V4V3 Pyruvate kinase n=181 Tax=root TaxID=1 RepID=A0A223V4V3_9FLAO  ali  36  5..................KKTKIVATLGPATSKKEVLKSMMLAGVDVFRINFSHADXXXXXXXXXXX-XXXXXXXXXXTAILADLQGPKLRVGVMSGD--VVVSPGDEITFVTGE--PFEGTAERVYMNYKEFPRDVKPGERILLDDGKLIFEVVTTNGESEVKAKVIQGGPLKSKKGVNLPNTNISLPALTKKDIKDAEFAISLEVDWMALSFVRFSQDLIDLQNIIKEHSPHIPIIAKIEKPEAVENIDKIVAYCDGLMVARGDLGVEVPAQEVPLIQKKLVLRAKKARIPVIIATQMMETMITSLTPTRAEVNDVANSVMDGADAVMLSGETSVGNYPVQVIEKMASILGSVEASELIKVPHD--PPHVRTNRYITKSICYHAALMANEIKAKAISTLTNSGYTAFQISAWRPSAHILVFTSNKRILTQLNLLWGVKAFYYDKFVS------TDQTIEDVNGIACKKGYLEVGDMLVSLAAMPIKAGMVNTLRVTEI 475
176 0.000e+00UniRef50_A0A2A6CGH5 Pyruvate kinase n=1 Tax=Pristionchus pacificus TaxID=54126 RepID=A0A2A6CGH5_PRIPA  ali  41 1096............................PTCDSVELIREMILNGMNIARVNMSHGNRDAHKRRIRMIKEAREAFPDHYVAIALDTKGPEIRTGPVKDHVPLKLKEREGYTVSVDET----GTKYCIYLDYPFIAEQLEIGKDLFIDDGVICLRVLAKHSEG-LHCEVITGGHLGSHKGVNLPSVRVRLPILSERDKEDLRLVIEEHVDLVFASYIRNRREVETVKYEISDSAKPISVIAKIENEDSLKNIDEIIDAADGIVIARGPLGVETPSAKVAIVQKMIVSKCNRNCKPVIIATQMLESMTLNPRATRAECSDVANAVLDGADCVMLSAETAHGKFPVGAVTVMNNICAEAETAYYQQSLLQDLRRQKGGTLNKLETMALSAATAVSCMNASAIVMITTSGKSAQICAQFRPPVPIVALCASKAIARKLHLYRGVLPFYVPETKVGPKMDVIEQALQMGIDQCKKRGFVKTGDPVVLITGWP.............. 1548
177 0.000e+00UniRef50_A0A2A5DCP6 Pyruvate kinase n=2 Tax=Planctomycetes bacterium TaxID=2026780 RepID=A0A2A5DCP6_9BACT  ali  33  6..................RRTKILATLGPACCEPARIREMVRAGVNGFRINMSHGDAETRAKWVRRVKRIRKEL-DKPISILVDLRGPRIRLGHLAQ--PRDFKRGDKVVVTPSKKEKKDGS---LPIDYRNLKRDLSVGDRILIRDGRVELKVVS-LDGKDIQCKVQRGGRVMANSGVNLPDSQVSAPALSAKDRVDIAFAVEHKVDWLALSFVRRAEDVLAVHKELKKHKFKIPVMSKIEHPQAIXELEGIFDVSDGVMVARGDLAVEMGHAIVPTLQKRIVRMAIERACPVVVATQMLESMIEADQPTRAEVSDVANAVLDGADCVMLSGETAVGAYPVETCRIMQLIAQKTESGQFHDTWRLRPPTGGLKXXSIEMATVNAAVYASHQAKAALILAFTESGRSARLVSSFRAKSPIVALSANERSFHRMSLYWGVAPGRLSKVRR------LREMNRHAAVYLKENHALRPDQYLVALTGTFSVSGVTNTVRIIR. 476
178 0.000e+00UniRef50_F7UCV0 Pyruvate kinase n=94 Tax=Alphaproteobacteria TaxID=28211 RepID=F7UCV0_RHIRD  ali  31  5..................RKVKILATLGPASSEEAMIEKLHLAGADLFRINMSHASHDVMRTLIQRIRSV-ESRNGRPIGILADLQGPKLRVGKFA-ETKVDLVPGQTFTLDNNDA---PGDNSRVFLPHPEILEAVKPGHRLLIDDGKLHLRA-EKCDGKSIVTTVVSGTRISDRKGISLPDTLLGVGVLTDKDRVDLDAVLENEVDWVALSFVQRPEDLAEVRKI---SRGRVGLMSKIEKPQAIERIEEIIELSDALMVARGDLGVEMPLEAVPGIQKQLTRACRRAGKPVVVATQMLESMITAPVPTRAEVSDVATAVFEGADAIMLSAESASGDYPVEAVSTMASIASTVEQDPYYSNIIYAQRPQPEATG--ADAISLAARQIAETLKLAAIVTYTSSGTTGLRAARERPQVPIIALSPIIQTARRLSVVWGLHCVVTGD------ASDLDDMVNRACRIVVSEGFGKPGDRIIISAGVPLGPGATNMVRIAYI 471
179 0.000e+00UniRef50_UPI00037A4B4D pyruvate kinase n=2 Tax=Hyphomicrobium TaxID=81 RepID=UPI00037A4B4D  ali  31  5..................RRVKIVATLGPASSAPDVLERLFIAGADVFRINMSHTSAETAHTLVRSIRDVAAKHR-CSIGVLCDLQGPKFRLGEFVDGRAL-VKAGEHFRF---DQTGVPGTSQRVSLPHPAIFDAVRPGHMLLIDDGKLRMRVADV-DGKSMVAEVVTGGILSSRKGISMPDTVLPISSLTDKDRKDLDIALKLGADWIALSFVQRAEDIIEAKRIID---GRAAVLAKIEKPSAIEDIDDIIAAGDGFMVARGDLGVEMPVERVPGLQKQITRKARAAGKPIVVATQMLESMTSSPMPTRAEVSDVATAVFDGADAIMLSGESAVGQYPVETIEMMARIAHEVENDASYDAFVHAIEFPPMPTGADAIA--AAAHAISETVKVAAILCYTATGSTALRVARERPNLPVIGLTPIARTAQRLALVWGIETVLTGD------PEDLADMVRKATRIAYEGGFVKPGQGVVITCGVPLGPGATNMIRLAFV 470
180 0.000e+00UniRef50_UPI000832D749 pyruvate kinase n=1 Tax=Rhodobacter sp. CCB-MM2 TaxID=1786003 RepID=UPI000832D749  ali  35  2...............IRTRRAKIIATVGPASAAPFMLRKLFNAGVDTFRLNFSHGDHATHAAVLRAIRALEAEV-GVPIGILQDLQGPKIRLGRLPGGAR-PVDRHERVTFV---QADRSEDPALLPLPHPEIFAAIAPGHRLFIDDGRVRLRVVSV--GERIEAEVTEGGMLSNRKGVNLPDTVLDLPVLTEKDRADLAFGLAEGVDWVALSFVQRAADLDEILRLID---GRAGLVSKIEKPSALEEIDAIAARSDAVMIARGDLGVEIPPEDVPARQKEIIALCRNLGRPVIVATQMLESMTSAPAPTRAEASDVATAIYDGADAVMLSAESATGAYPAEAVEVMDRIIRRTEGHGAYARTIAATRSHAEG---TALSIADSGAVLACAIGARCLVAYSMSGATAQRVAARRPALPLIVLTRDARVSRRMALVWGARSVL------ESAALDYDSMVSMAREESARLIGPEPGDSFVILAGVPFGSGSTNNIRVAT. 467
181 0.000e+00UniRef50_A0A2V7ZCC3 Pyruvate kinase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V7ZCC3_9BACT  ali  35  3..................RRAKIMATLGPVSRDETVLRGLVRAGVDLFRLNLSHGTQEQHRETLRRVRRVAGE-ENCHLPVVLDLMGPRYRLGLIPDE-PRLLKPNQEVVLGREEQHAD------LPVD-PEILEHLQPEERVLIDSGLIELRVESKQGDR-VQARVVNGGPIKTRKGINLPDTDLPFE-VSEKDRSDIAFAVAEEADYLAASYVGAASHVEAIREVVSAAGGRIPIIAKIERKTAIEKLDEITVAADGLMVARGDLGVEVPLYTVPVLQKKIVAAGRLSGKPVIVATQMLESMIEQPRPTRAEATDVANAVFDGADVLMLSGETAAGKYPVLVVETMARIIQEAEDYVRQNNEPPKLQPLGPAGTDVTDIVSAAAVYAAGQIGVRRIVAFSQSGFTARLVARYRPPSPIMAFTPDARVARQIQLIWGVRPFVAE-----FQVGSLEDIVNVVERELLAAKLVVPGDRIIILMGHPVRERPANLLRVHLI 485
182 0.000e+00UniRef50_B5Y8W1 Pyruvate kinase n=3 Tax=Coprothermobacter TaxID=68335 RepID=B5Y8W1_COPPD  ali  35  1.................MKLVKIVVTTGPSLEDLDKIREAAKAGADVFRLNLSHGSYDEHIKRIENIRAVEKEIE-RPLAILADLQGPKIRITSTVTEEGIALQEGKDIKLRYG---SDACTGEVLYVDYPYLVEDVEVGSLVYLDDGKIQLRVISK-DNHELTAQVVAGGIVTSHKGISFAGARLRLPALTEKDLKDLDFLCTQDIDFVGLSFVREPEDVMDLRRRLDKAGRDVGIIAKIERHEALEDLNAIVDVSDAIMVARGDLALDIPLEDLALVQKEIIRICVEKCKPVIVATQMLDSMIERPFPGRAEITDVANAVMDGSDAVMLSGETAFGKYPILAIETMKRIIETAETYPFRTPNF-------LTPKSVREALVESAVRIAERSGAELLVVATETGASARITSAFRSVVPILAVTHNDRLQRQLCLSRAVIPIKTEASASA------EEVLKTSVKWSLDHRIANKGDLLLYIFGDLTGAGSTNSVKIYRI 467
183 0.000e+00UniRef50_A0A2E2AN71 Pyruvate kinase n=22 Tax=Bacteria TaxID=2 RepID=A0A2E2AN71_9CHLR  ali  34  38...................KTKIVCTLGPATETDEKIRDLITAGMSVARLNLSHGTLDSHEVALKKVRAASDEM-GVSVGVMVDVPGPKYRTGYQEPGV-IDLVTGATLVLTSRDMM---GNPDVLSVSPNGIHRDAIIGGTILIDDGNVRVVVTDIQ-DEDVTCRVTHGGRVVERRGVTTPGRAPDLPFLDDRAETGLIFAAEMGADFVALSNVTEDGDIEQARELLKKHGPEPYIISKIERAEALENFDSLLDASDAIMVARGDMGVEVPLELVPVYQKRLIARCNEMGKPVITATQMLESMISSQTPTRAEVTDVANAVFDGTDAVMLSGETATGENPITAVEVMRNVAHHAEANLPYASIIRD--KEAQLENQTSDAISYDACRTAFQLGADLIVTFTETGSTAGRVSKYRPVAHILALTPXESVXRVLTLRWGVVPVIXSGVR------NVEEFFVVGERHALASGHIPDGXKVVLVAGLPIGVGXTNLLRVMDI 506
184 0.000e+00UniRef50_A0A0Q9YIX4 Pyruvate kinase n=2 Tax=Proteobacteria TaxID=1224 RepID=A0A0Q9YIX4_9COXI  ali  35  4..................RRTKIVATLGPATDSKSKITDLILAGANILRINLSHGTFEQQKEKILLAKECATEL-NKIVGILVDLQGPKIRIQAL-EERYLNLQENDSIVL--DPTITYPGNTDGVGVNHPELPKEVVVGDELLLDDGRITLSVKDIQ-GSRVICQVISGGKLLPFKGLNKKGGGLSLPSLTEKDKQDIRSITGLPIDFVALSFPKTADDIRYARSLLKEQNNPAHIVAKIERAEAIENIDEIIEASDAVMVARGDLGVEIGYAELPGIQKYIINRASLSDKAVITATQMMESMITNPIPTRAEVSDVANAILDGTDAVMLSAETASGEFPIKVVAILHEICKAAERQRFARAARNRVESLCERSD---ESIAMAAMYIANHLKIKAIVALTESGSTPLLMSRIRSTIPIYAMSRHAETCRRMTLFKGVHPVYFDVTQFNAWDIS-----KYALDKLIQMKILKEGDNVILTKGNIIGIGGTNTLKILE. 472
185 0.000e+00UniRef50_A0A2I1DJP7 Pyruvate kinase n=142 Tax=Bacteria TaxID=2 RepID=A0A2I1DJP7_9PROT  ali  33  1...........MKSLPRHR-SKIVCTIGPASDQSKTLEAMIRAGMNVARLNLAHGSAEEHRARIARIRQAA-ENTGQRIAILADLPGPKIRIGKLP--APVTLKHGDHVLLAPD----APGTAQAIPLELPPLAKPLVKGDTVFLNDGFLQLRV-EKHDAHGLFCQVVVGGVLLSHKGVNLPGVQLDGGAVTPADRQLLAFALEAGVDGLSVSFVETAEDLHAARREALALGYAPFLVAKIERAKAWKEIDAIIAATDAIMVARGDLGVEVPIEEIAVIQKRLIRKARAAGKPVITATQMLESMVHNRRPTRAEVTDVANAILDGTDCLMLSEESAMGDYPEEAVKMLAQIAQVTEKNRTELSPLQATDLH--DHASVESSIANSVRHSAEHLHPRFVVTPTETGATAARIARFRLQPWILAMSPHAATCQRLCLYYGVHPIEMASPERGWEY--------AARRWLVENG-VEKG-LILLTQGSKGHPGGTNRLEIL.. 467
186 0.000e+00UniRef50_A0A0M0BS72 Pyruvate kinase n=2 Tax=Candidatus Bathyarchaeota TaxID=928852 RepID=A0A0M0BS72_9ARCH  ali  39  2...................RSKIVCTIGPASQAPETLGAMAEEGMDVARLNLSHGELGRHREV------AEALLDMGGVSILVDLPGPKIRIGEI--DGRIVLRPGDQVHFTTRRVM---GDGRELPVTYEGLPREVRVGGGLFLDDGLIEIRVASIDADRGFLGLVVSGGEIVSHKGLNAPGARLSLRPPTERDVRGIEFAVEVGADWLAMSFIRDGEDVESTRRALERAGGDQPIISKIEHRDAIGNIDEIIEASDGVMVARGDLGIEVPPWEVPILQKRIIARCNRQGKPVIVATQMLESMMENPRPTRAEASDVANAILDGADAVMLSGETAVGLFPVEAVKVMNSISLSAE-----RQGPSREDRGLVEGAPIPEVIGSLASRATEAVRPAAIIVVTRSGFSARMVSKHRPRARILAVAGSPSVSRRMRLYWGVEPLDV------AWTDDRDDLLIRAVDRSLEMKLVGEEDVVMFVSGSTLEPGRTSTLEVLRV 462
187 0.000e+00UniRef50_F0Y8C0 Pyruvate kinase n=1 Tax=Aureococcus anophagefferens TaxID=44056 RepID=F0Y8C0_AURAN  ali  42  30.................HKRTRIICTLGPSSWDVDMLGVLLDEGMNVARLNFSHGDHETHKRTIGRLKEALAIRPGRHCAIMLDTKGPEIRTGFFNDGGKLKFAKGDPLILTTD--YDHKSDGTKLGCTYKKLPTSVKPGGQILVADGSLVLEVVSTDGTAEVTCKIMNDCAIGERKNMNLPGVLVDLPVLQDKDTKDLEFACPMGVDFVAVSFVQSAADVRTVRKTLDGAGGKIKIISKIENQEGLDNFASIVDETDSVMVARGDLGMEIPPERVFRAQKSMIATCNGAGKPVIVATQMLESMVSNPRPTRAECSDVANAVLDGADAVMLSGETAGGSFPKEAVAIMARTCVQAEGEFDFDAAYQKELATMRESLSVVESTVSAATQASRDAAAKAIVVLAASGATTQLFAKYKCGIPLIVVTAHDSVARYAALIPGAYVLHVPDLVKYGYADDTGDMVAEGTKFACSLGLVTSGD....................... 518
188 0.000e+00UniRef50_A0A0G0JGM0 Pyruvate kinase n=1 Tax=Candidatus Daviesbacteria bacterium GW2011_GWA2_38_24 TaxID=1618422 RepID=A0A0G0JGM0_9BACT  ali  36  4..................KKTKIVATIGPASWDPSTLEALAKAGMDVARLNFSHGTHEEKGAQIQHVRNISQKL-NKPIAVMADLQGPKIRLGKIEGDNKLMLKKGQTIELSTEPK------EGQLPMQF-DLSPFVKKGQRILLNDGLVQTNVDGV-SGKTIRATVQNDGWVSSNKGVNVPDTLLPGASLTSKDYADAEFALRAGADYLAISFVQTIDDVKAARDIIKKANSRAKIIVKLEKPQALENLEEIIQITDVVMVARGDLAIETEASKVPLVQKRILQLGRQYFKPVIVATQMLESMTENPRPTRAEVSDVASAVFDQADAVMLSGETANGKYPVQAVEMMQEIIESVESQEEYRNYISVDMAEVEVKELSERALAASAALLSELVEAKLIIVGTATGRTALSLSTFRPEAQIVAITHDEQTKNQLALLWGVRPYVV-------QPNEVEAFWKQTLELAKESKLVKKSDKVVTISGSVIGSGQTDTIRLATV 478
189 0.000e+00UniRef50_A0A2A5WJ37 Pyruvate kinase n=1 Tax=OM182 bacterium MED-G24 TaxID=1986255 RepID=A0A2A5WJ37_9GAMM  ali  33  4VTHVDHL---------RYRRTKIVATIGPASDSRETIRSLVEVGVNVFRLNMSHGEHTTHRSVFEHIHEISEA-SGQPVAVLADLCGPKIRTGRFPSG-PIELINGKTVTVTTREVDGQAG---VIPSQYPDLHNDVTSGDRILIADGLIELRVVAV-DAQDIRCDVVHGGTLSDHKGINLPGVNVSAPSLTDKDRMDAQFALELGVDFIAMSFVRNADDMNVLRELVKGAEHSPSLIAKIEKPEALENAEAIITASDGIMVARGDLGVELAPEEVPLAQDELIQLARRNNKPVIVATQMLESMIVSARPTRAEVTDVTYAVSSGADAVMLSGETAVGIHPVETAATMDRIARQIEAHLNRQGMWGRLVEHQDSGV-LATVVADATSHMSKALAARGIVVISQTGISAVTVSNARPAAPIIAITSSDRVFRRMSLMWGVIPVI-------QSAAGVENPNELARQVAGALSLATTGEVVLLVRGFHDEPG.......... 470
190 0.000e+00UniRef50_A0A2N6AMD9 Pyruvate kinase (Fragment) n=7 Tax=Firmicutes TaxID=1239 RepID=A0A2N6AMD9_9FIRM  ali  45  1.................MRRTKIVCTIGPASEDKEIFTELVKSGLNVARLNFSHGNHEEHKKRIEMIKEVRMEM-DIPIAIMLDTKGPEIRTGLFENG-YAELETGGLFEITVKDII---GNDNISSVSYVGLPEDVSVGSKILIDDGLIELEVEEIKDSESVICRILNGGMVKDRKSINIPDVQINLPALTEKDIEDIMFGIENDIDYIAASFIRKADDVNAILKVLEDNGGDINIISKIENRQGVDNIDEIIEASKGVMVARGDLGVEIPTEEVPMVQKMIIRKCNIQSKPVITATQMLDSMIRNPRPTRAEATDIANAILDGTDAIMLSGETAAGKYPVESIKTMANIARITEESINYRKVLAEKRKLKAE--SITYAVSHATCSTALDLDATAIITTTASVYTPHMVSKFR..................................................................................... 392
191 0.000e+00UniRef50_A0A0L0DG21 Pyruvate kinase n=1 Tax=Thecamonas trahens ATCC 50062 TaxID=461836 RepID=A0A0L0DG21_THETB  ali  42  21VSSLSKLVDLDVRHPSRDRKTKVICTVGPATWDASGISSLLDAGMNVMRLNFSHGSYEDKAKAIATLRAELDRNARSLCAIAADTKGPEIRTGAVADGKAVELVGGSTVEITTDPQFATSCTASRLFLDYPDFANEVSEGQTVFVDDGLIELTVTGLHPGEAVDAKVVNGGMLGSGKGINLPGASLSLPAVSERDAADLAFAVEQDMDIVFGSFIRSAADIADIRTALGPAGAHIMVMAKIENWEGVLNFDEILAASDGIMVARGDLGIEVPASKVFLAQKSMLAKCVLAGKPAIVATQMLESMVKNPRPTRAEVSDVGNAVVDGADAVMLSGETAVGAYPQAAVQIMGKVCQEAEAVIDHGELGASIRGRHAAYEDVLVSVGDHHKDATRDIQSPVIVVLSASGGTARDVARFRPEVPIVAVTDDARVARQLNVSKGVFPVVVAPAP-------LDAMRASGVAFGKSLGL............................ 511
192 0.000e+00UniRef50_A0A1Q3NKP4 Pyruvate kinase n=2 Tax=Solirubrobacterales bacterium 67-14 TaxID=1895832 RepID=A0A1Q3NKP4_9ACTN  ali  34  6..................RLTKIVATVGPASWDPAVLEEMILAGVDVFRLNFSHGDAATHVRVVKDIREASDRL-DKEVGILGDLPGPKLRVGEYPQGV-VDLVHGTTVTITSEDV---DGTATLIPVDWPELCDALKLEDTVYLADGSIRLRVTA-NDGKVVEAEVEVGGPLSSHKGMNLPGVEEGLASVSEDDLGWVEFAVANQLDYIAVSFVRSAADLDPVLDKLKELSSSIPIIAKIEKPQAADAVEEIVEATGGIMVARGDLGIEVPLAKVPVLQKSLIRTAGKAGKTVITATQMLASMVSAKRPTRAEVTDVATAIYDGTDAIMLSEETAVGDYPVEAVKVMDQIARGTETDLPYWDWV--LNRVRQDEMDVSDSVTQSAVIAAYRLNLQAIVVPTASGRTAKVVAAHRPRVPVLAVTHSVRTQRQLKLMFGVRPVV------NDQTTEIRNLLYECADDAVTYGAAKSGDLIAIVAGLSDMQLGTNLFEVHRV 474
193 0.000e+00UniRef50_A0A2R5G8R2 Pyruvate kinase n=1 Tax=Aurantiochytrium sp. FCC1311 TaxID=2023137 RepID=A0A2R5G8R2_9STRA  ali  38  90..........KVPNPSKL-MTKIICTVGPATCSKQKLGEMLDAGMSAMRLNASHGDYEFFKTAITNLREAAESRR-RICPVILDTKGPEVRIGRFPVEN-IEVQNGDTFTFYCD--YDREGSAQGVGTTFDRLAQTVAIGDVILVDDGRLSFLTREIDEATDVTCSVIMGGVIKSNKGLNLPGCPIDLPHLTEKDYKDIAFAVEQRVEYIAHSFTRSAAGILAVREIPGVVETGIHVIAKIESQEALNNINAITSVSDGIMVARGDLGVEIPLERVCSVQKRLIRDSNLAGKFVITATEMLDSMIHSPRPTRAEASDVANAVFDGTDCVMLSGETAVGSYPVATIQVMNRICKEAELDIEQHKRTHVLKNATGRFRDLNEAFSMAAVATAKDIDAALIIAVTKTGQTAKTLSKHFPTVPILALATSPKICAQVSLYRGVIPYLVHSLERASC-------VPRGIAKATELGLVSHGSRVVLVTGH............... 561
194 0.000e+00UniRef50_B2KCJ2 Pyruvate kinase n=1 Tax=Elusimicrobium minutum (strain Pei191) TaxID=445932 RepID=B2KCJ2_ELUMP  ali  32  11.....................KIVATLGPNTSTEEMIDRLVMSGVSVFRFNCSHGSLEEYQQRIKGIRAAEKKY-NCNIGILFDLQGPKLRIGRFKDSAVITLKEGDKFRVDLSP---EPGDKTRVSLPHPEIFQAMQEGLELLINDGIVRVRVDSFTADSA-ETTVIAGGQISDRKGVNVPGAHLPISALTEKDLKDLKMAEDLGADFVALSFVQKAEDIIYLRSLMR---SQAGVIAKIEKPKAVEDLDKILEVTDVIMVARGDLGVEMNSERVPVIQRRMINACRKAGKPVIVATQMLESMVNNVTPTRAEASDVATAVYEGADAVMLSAETANGKHPIEAVSTMRRIITTVEREIKIQEPPVSFKVADNPEQAIIAAAGMSAKTMAM---ASLIINFTDSGTTTKRTAKERPYVPILSLTPYEDIARRMTLVWGVTSMKVKN------LESFDDILREARAAALASGMAKEGDKAVITAGVPFGSGDTNLLYIVSI 473
195 0.000e+00UniRef50_A0A1Z9UNA1 Pyruvate kinase n=2 Tax=Bacteria TaxID=2 RepID=A0A1Z9UNA1_9BACT  ali  35  2...........TPTDIRKRRTKIVATLGPASSSETVISELITSGVNVFRLNFSHGTHEQHRSNVKMVRELSQKH-NRHVGILGDLQGPKIRIGELQTET-LQLVNAESLILTIDQSTAD-STNGRIHVTYPYLPSSVGEGDTLLLDDGLIRLKVISVT-GNDVACEVTQAGLLKSRKGLNRLGGGLSADAITEKDLEDLQVIIDLDFEYVAVSFPCCGDDLLPVKNVLKKTGSAAKIIAKIERAEAVEKVKELIDAADGVMVARGDLGVEIGDAQLISIQKRIIRLSRQANKPVITATQMMESMINHPVPTRAEVFDVANAVLDGTDAVMLSGETASGKYPAKVVEAMAETALGAEKHPMMKQSSYRVDRV---FDEINESVAMSAMYAANHVNVTAIVCLTESGITPLLTSRLSSILPIFGISPHLATCRRMALYRGVIPIYYDVMA------DEGDLWTKAMALIVERGALQPGERVAITAGDLHGKGSTNTLKILQ. 481
196 0.000e+00UniRef50_A0A2A5XHB1 Pyruvate kinase n=1 Tax=Bacteroidetes bacterium MED-G21 TaxID=1986267 RepID=A0A2A5XHB1_9BACT  ali  31  1.................MNNTKIIGTIGPSSCDKSILRKMFAEGLNVVRINFSHSDHKKALQVYKWVQELNEE-ENRNVATLGDLQGPKLRIGDVKEDQ--TLKKGEKITITTEECI---GDMSKIYITYPNFPKDVKVGDKIMLDDGKIILKAENSNKKNEVEALVIQGGELNSKKGVNLPNTKISLPCLTSKDLDDLEFALEVGIEWIGLSFVRSVNDIKKLQKIISEKKSPAKIVAKIEKPEAIQQIDAIIKKSDAIMVARGDLGVEVPMERVPNLQKMITRKCIKYSTPVIIATQMMESMMKSLSPSRADVNDVANAVHDRVDAVMLSGETSVGMYPVEVIRAMSKVLKSQENYAN-LEMEEFLPVEKNDGRYISDTVCYNACKIAEQVDAKAVMTMTHSGYNAFKISSFRPPSKICIFTHNRQILNTLSLLWGVRGYYYNKFVS------TDDTITDIKKIIKENKVAQSGDMVVNIASMPINKGMTNMLKLSMI 471
197 0.000e+00UniRef50_A0A2E6MN25 Pyruvate kinase n=12 Tax=Gemmatimonadetes TaxID=219685 RepID=A0A2E6MN25_9BACT  ali  33  1.................MLRTKVVCTLGPASSGRGSILALVQSGMNIARVNMSHGSREDHARIIESVRAAARE-TGKPVGILVDLQGPKIRVGELNQ--PLELNSGDEVVVAPEASAVQG----EIPTTYAQLAEEIAVNDAALLDDGLLEFRCVRTEGDRTVF-EVIRGGLLKSKKGINLPNVDLKTPSMTDKDLQDLDFALQYQAEYIGLSFVRKPEDVVDLKRRV---GGRALVVAKIEKVQALKVIEEVIAESDMVMVARGXLGVELPFQRVPLVQKRIIQLANYHGRPVITATQMLESMIESARPTRAEASDVANAILDGSDAVMLSGETAIGKYPLRSLEAIVCIGSEIERSGFLERGPRYLTAPGGLRTRREHAIASATVEAAKQIGAPAIVVITKSGFSARLVSSYRPSMPVFAVTTEQTTFRQLAAVWGVHPVLAEDVEVT-----YEELSDVGMQSVLEAGVGEKGASVAITAGFPFHQGSTNNMRL... 470
198 0.000e+00UniRef50_A0A2V9ICB1 Pyruvate kinase n=4 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V9ICB1_9BACT  ali  34  1.................MRRAKIVATIGPASDSEEKLRDLLQAGVNVARINMSHGARERHGEVVTRLRRIAAE-SAQPMGILLDLAGPKIRTGRLRGGVAI-LKDGAEVRITGEDI---EGDARRFSASYPRLAQEVHPGDRILIDDGEIVLEVVDTKLG-DVSARVIHGAPLGERKGINLPGSHISVPSVTEKDIADLQFGVERSVDLVALSFVRSAADCAQARDLIRKFGSRALLIAKIEKPEAVDDLSNILDTSDGVMVARGDLAVETAPEIVPVLQKRIIFEAMSAEKIVITATQMLQSMILNPQPTRAEASDVANAVLDGSDAVMLSGETAVGRFPVEAVQMMDRIIRSAEEMGLPPSQLSEHQLMTRHSGSQGRAIAEAATFAAAEVDSRLIVVFSKSGIMARHIAALRPPQRIIALTSSERTYRQLTLAWGLEPYMLEELPP-----DSDAILASGDRTLLRHNLADAGELVVLMTGQLVDAAISSSMKLHRV 486
199 0.000e+00UniRef50_A0A0B3A5N9 Pyruvate kinase n=1 Tax=Archaeon GW2011_AR4 TaxID=1579366 RepID=A0A0B3A5N9_ARCG2  ali  34  1.................MKKTKIVCTLGPCSRKPAVIKDMIKAGMDVARINMSHGSHEYHKETINLLRGINDS-----IPIIADLKGPEIRIKEI--ERPVFLSAGDRVKLCGKEKVG------CLLIDYRNVHEAVSSGSRILLDDGLIELGVDAV-ENDVVICTTKNSGTLNNNKKVTIPGGNLVIPFPSKHDKEDILFACEHKLEFIAVSFVKQKEDITAVRKIIGD--SQCLVIAKIETRESVENIMDIIQESDGIMIARGDLGVELAPEEVPFIQKYIIRLCNKMGKPVITATQMLESMIKNPRPTRAETSDVANAILDGTDAIMLSGESAIGEYPSQAVQVMTKIALRMEKLVRH--------SISDVGASISQSISHAAYQLSLNEFVTKIITTTTSGFSARMLVRFRPRKQVIAVTHDPLVRNQLMLDWGVIPLCFSHKVRH-----THQIIDNALESCLSKGLINQEDVVVLTAGITLDAGHTNLIEIHRV 455
200 0.000e+00UniRef50_A0A2E2NBC3 Pyruvate kinase n=4 Tax=Bacteria TaxID=2 RepID=A0A2E2NBC3_9BACT  ali  33  22...................HAKIVSTLGPASDSPAMIERMIEAGVNVFRLNFSHGTLDQQLVRLQRVRDVAKSM-GRTIGVLGDLQGPKMRVGDIDDGGGIFIETGQEIEFRKGKCPSGEGPAAVFGVTFDALYDDIQPGQRVLVNDGAIRMLVTEVDVGKSVRCRVTHGGRVTSNKGVNLPETDLSMPAITDRDWKCVDWGLEHGIDLFALSFVRFAEEVRELKSYLLSKGLQIPVIPKIEKPQALQNLDEIIEASDGVMVARGDLGVEMEVFEVPVWQKHIVGRCAALGRPCIVATQMLESMITEPAPTRAEASDVANAIFDGADAVMLSGETAVGAHPDLVVATMARIIRAAEDRIDQLALQAHPMPELPELPFRSAALAAGAWHIADRVGAKLVVVWSQTGGMARYLSTHDFRVPILAYTSNEMVARRMTVLGGVTPICRPAPEDATWTHDVEDMIRAC-------GYAEDGDAVVMIAGKPLGGRHQDIMAILRV 518
201 0.000e+00UniRef50_A0A0J7HS49 Pyruvate kinase n=1 Tax=Chitinispirillum alkaliphilum TaxID=1008392 RepID=A0A0J7HS49_9BACT  ali  37  5.................LRKTRIVATVGPGSSSAEKIKELLLAGVNVFRINFSHGNHQIQSERIETIRKVSDSLGLNP-ALLADLQGPKIRTGKTDGGRSVTLSSGSEVTITSDDVV---CDENLISVDYPHLVEEISVGQRIMINDGLIKLEVDEIDKTNRIHCVVVDGGVYSSRKGVNLPNVDLSVPSLTEKDREDIGLIVENDFQYVALSFVRRGKDIEKLREIIAPVRPDLKIIAKIEKPEAADNIEEILGVSDGIMVARGDLGVEMSPDVVPVVQKDLIRKANDSGKIVIVATQMLESMINHPLPTRAEAADVANAIIDDTDAVMLSGETAVGSYAVQSVETMSRIAFAAEQSEYCSTEIIDFHNSDRYP---PHAMAEAAVWAARDMGGIPICLYTLSGDTAFYMAKLRNQSPVYVFSPDIHVVKMLSIAWNVEAFHL-----SFSEGDQVRMLRSGEEILVRKGILESGDTIAVLAGTTPVRGATNILRIKKV 476
202 0.000e+00UniRef50_Q40546 Pyruvate kinase isozyme G, chloroplastic n=365 Tax=Streptophyta TaxID=35493 RepID=KPYG_TOBAC  ali  33  91..................RKTKIVCTIGPSTSSREMIWKLAEAGMNVARLNMSHGDHASHQRTIDLVKEYNAQFEDKVIAIMLDTKGPEVISGDVP--KPILLKEGQEFNFSIKRGV---STEDTVSVNYDDFINDVEAGDILLVDGGMMSLAVKSKTSD-IVKCEVIDGGELKSRRHLNVRGKSATLPSITEKDWDDIKFGVNNQVDFYAVSFVKDAKVVHELKDYLKSCNADIHVIVKIESADSIPNLHSIISASDGAMVARGDLGAELPIEEVPLLQEDIIRRCQSMQKPVIVATNMLESMIDHPTPTRAEVSDISIAVREGADAVMLSGETAHGKYPLKAVKVMHIVALRTESSL--QKSTSSPSQSAAYKSHMGEMFAFHSSSMANTLSTP-IIVFTRTGSMAIILSHNRPSSTVFAFTNNERVKQRLALYHGVVPIYME------FSSDAEETFSRAIKLLLSKSLVKDGQYVTLVQSQPIWRRHTHHIQVRKV 560
203 0.000e+00UniRef50_A0A2N0UIZ1 Pyruvate kinase n=7 Tax=Ruminococcus TaxID=1263 RepID=A0A2N0UIZ1_9FIRM  ali  35  1.................MRKTKIVCTIGPACDSKEMMRKMIDAGMNVARINMSHGVYDQLEVTIKNLKEAIAE-SGQNVAILLDTKGPEVRVGTFKDG-SVELSEGAEFSLFKNK---EEGDETGVSLSFPKLVDIFEIGRELLLDDGIISLVVKSVNP-ESIVCTVNKGGVLKNRKSINIPGYFINMPYVSAQDRKDIEFGLNHGATVVAASFVRNHDDVRTLRDFIDSLGYEVEIIAKIENQSGVDDMDAIIDYADGIMVARGDMGVEIPFIKLPEIQKTIIRKVVSRGKYVITATQMLESMTTAPRPTRAEISDVANAVYDGTSAVMLSAESAAGKYPIESVKALDAICSEAEENGEFTALHEYVEEHGMKDTNPIRSICKAAKNIAQAVGAKAIIVESATGRVARAMVHYRPDCPVIAVATSQLVCRKLCLNWGVMAVMGEEKRTS------DSITKQAMEKALSTGVVKKGDTVVVLSSNKTPTSSTDSLNVR.. 478
204 0.000e+00UniRef50_A0A1P8WJ70 Pyruvate kinase n=16 Tax=Planctomycetaceae TaxID=126 RepID=A0A1P8WJ70_9PLAN  ali  33  13...................KTRIIATVGPACENAEVLRKLIVAGVDVFRLNFAHGSHEWLSGILATIREVAAELK-TPVGVLGDLSGPKIRLGEIADGE-VYCAEGTMFRFV---RAANSGVSTDLTCTYEKLIDDVDPGDRILLADGTVSMLVTAKDDGQSVNCLVAEPGIIRSRQGVNLPGVALSTPSVTEKDEFDLKWALQNRLDFIGLSFVRSAADITHLKQLIEANGSRPLIVAKIEKTEAIADLKQILEVTDAVMVARGDLGVEAEISRVPILQKDIIRRSNAARIPVITATQMLDSMTTNDLPTRAEVSDVANAVIDGTDAVMLSGETAIGQHPVTCVRMMQKIIDEAEPYVIRTGSGDRLSQEFRRANPITEAVSLGATIVAEDLDADLIVVATESGRTALALSRMRGQVPILAVTHREDTVRRMCLFWGVTSIQSKLVRQSA-----DALLQYVVQWGLENRVLKSGHKIVVV-------GHTNLMMVHVV 486
205 0.000e+00UniRef50_A0A2D9HD54 Pyruvate kinase n=1 Tax=Myxococcales bacterium TaxID=2026763 RepID=A0A2D9HD54_9DELT  ali  33  17.............SYSNFCRSKVVATVGPASSSADQIRGLIDAGVDVFRLNLSHGDHAEHKAVHQVIREATADC-GRAIAIVADLQGPKIRVGPMPP-TGVTLVKGEPFILTTEG-PVQEGTASRAWLDAPSLSSDVKAGHSILMDDGRLRVRVVNV-EGPEIQCVVEVGGLLQSRKGVNLPDTQLSLPSLTPKDEVDLEFILKLGVEFIALSFVRSESDVLTLRQRIGTGFDDSGIISKIEKPEALQNLNRIIAASNGLMVARGDLGVELSPEKVPMAQKAVIQAARRQGRFTIVATEMLQSMVNASRPTRAEAGDVANAVLDGADAVMLSQETSIGDHPELVVETMRRICREVESTGAYAQSRAVTSPEIEGHGSIQNACARAALGLAADLRAKAICFFTATGTTARLSTDYACDVPVLAFTPSEAASRRMAIYHGVTPIHL------NVPTTVDGTIDRMTQELVDRGICSLGDLVVVTASRPTALGGTDTLRVVRV 495
206 0.000e+00UniRef50_A0A2U2SD25 Pyruvate kinase n=1 Tax=Anaerolineae bacterium TaxID=2052143 RepID=A0A2U2SD25_9CHLR  ali  32  2.................VQKTKIIATLGPASSDFTTLSELIRAGVRIFRVNCSHGSESERICLVQRAKQVSESLA-IPIAVLIDLQGPKIRIGELEK-PSITLQSGRRVIIT---DQPVQGNEKSLSIELPGLFEHLQVGHRILLDDGKIELKVIQKGKNT-LETEVIVGGALLPRKGANFPDSELPLSGITQKDLRDLQVGLQNSIDAVALSFVQNGQDILDLRKQIKEKKKDVPIIAKIERPQALLHLSDILEQADGVMVARGDLAIEISPACVPTAQKQIITTANRLGKYVITATQMLESMIENAVPTRAEANDVANAVFDGSDAVMLSAETSIGKHPIRAVQTMVSIIEEAEKNLAQWSVWNGKLIPKSEDEDSYYVI-QAAHDLSEDRNVTAICVFTQSGRTASLLSKTRPKVPIYAFTPNPDTHSRLSLFWGVESILTPR------ANSLDEILAIIQSTLRQQFPIKSGDQAVLICGYPVHQRSANLLMLYTV 475
207 0.000e+00UniRef50_A0A2D5BNW2 Pyruvate kinase n=2 Tax=Planctomycetes bacterium TaxID=2026780 RepID=A0A2D5BNW2_9BACT  ali  35  5..................RKVKIVATLGPASRSPDVVSEMVAAGMDLARLNCSHSSHDELEEMATLVRGCSRAVE-RPVGLLLDLAGPKLRTGKLKGGGPVTLERDAEFVIGPDIVL---GDGTRVGVSYDRLAEDLAVGQRILLNDGLLELQVEEIR-GRDVVTRVLVGGLLGERKGLNLPGTQLRLPALSEKDKADLAVGVRIGVDYVALSFVQSPDDVRVLRAELDLLGSDIPIIAKIERPQAVAQLEEILAVAQGVMVARGDLGVEAGSHRVPLIQKRILHEASRRAVLDITATQMLESMVHSPRPTRAESSDVANAILDGTDAVMLSAETAVGEYPVEAVAMMDKIAMEVQEGVDHERFVPEDLLLPDGPAAAVARAAG---HIAAAERYETIIALTGSGWTARMLAAFAPNANIIALTPSEKAFGRLTLVRGVQPVFLP------FTGGTDSILASGEAELRRRGLLQPGEDVILVSGELDSWGVTHLLKIFTV 472
208 0.000e+00UniRef50_R6UDN4 Pyruvate kinase n=2 Tax=environmental samples TaxID=2231195 RepID=R6UDN4_9CLOT  ali  41  1.................MKRTKIVCTIGPASEKPEILETLIKSGMNVMRLNFSHGDXXX-XXXXXXXXXXXXXXXXXXVAFMLDTKGPEIRTTDFADDAKHTFNEGDKVTLTTRDI---KGDNSTLGITYKGLPNDVEVGGHILIDDGLMDLLIESI-EGTEINCKVLNSATIKGRRGVNVPGAKLKLEAMTEKDKSDLKFGVENDCEFIAASFIRKAQDVIDMRNYLKSVGGDVKIVSKIENQEGLDNFKEILEVSDGIMVARGDLGVEIPEELVPAAQKMMIKETAAAGKFVITATQMLESMQHNPRATRAEVSDVANAVYDGTSATMLSGESAQGDYPREAVKTMAKIDEATEKDICYWNRFKKRNIDYFKNIEKATSINFAVCCSAMFANADAIIAVSKDGVTPSLLSSFRPGCPIYVVTSDAKTYKQMAVENNVTAILIEN------TEDYDALLEKGIEELKSRGLVKSNDTVVLSGGI............... 468
209 0.000e+00UniRef50_A0A2E6P2G6 Pyruvate kinase n=8 Tax=Proteobacteria TaxID=1224 RepID=A0A2E6P2G6_9GAMM  ali  32  1.................MRRTKIVASLGPSTDDPKAISNLVRSGIDVARINFSHGDQEEHRKRGSWVKKASVT-QGRTVALLCDLQGPKIRIKGFSK-RSVQLKNGKPFIIDI-ALDEIAGTEERVGTTYKGLANDVKRGDTLLLDDGSISLRVESV-EKNEISTRVVVGGELFSHKGLNLQGGGLSAEALTDKDQDDINFLTEVGADFVGVSFVRSADDVEHARDLVRTVGSNAHIVAKIERREAVENIESIVRAADVIMVARGDLGVELGDAELPGVQKQLIAEARAGNKVVITATQMMQSMISSSQPTRAEVLDVANAVLDGTDAVMLSAETAVGRHPARVVAAMDRICRGAER---QHSAMVSTHRLDHYFESVDEAIAMAAMYTANHHDIEAILALTESGKTPMWMSRISSGIPIFAATRSEETERRLALYRGVYPVPFDATMVSRSDLNW-----AAVQEIRDRGLVEDGHKIILTKGDLYGSGGTNAMKIVKV 472
210 0.000e+00UniRef50_A0A1C0B8C5 Pyruvate kinase n=19 Tax=root TaxID=1 RepID=A0A1C0B8C5_9PROT  ali  38  3..................KKTKILATLGPASNSLEMIEKLIKAGANMFRLNFSHGSHEYHKESIDNIRQAMKNC-GTRVGILQDISGPKVRVGELK--EPFNLVANDTVTIIEKEIYKKAEGEYIVSINHPEILGKIRVGEFIYLYDGIIRAKVIDVKDG--IKTRIENHGTLSSRKGVNFPNTVINIDVITEKDEKDIAWGVENQVDYFAISFVQNANDMKRARELL--NGYNGKLIAKIEKFDAVSNIDEIIEQSDGIMVARGDLGIEVPYYEVPTIQKMLIRKANAKGVPVITATQMLLSMTQNERATRAEISDVANAVLDGTDIVMLSEESAVGDNPENVVETMSNIITKTE------DIFNHKKRDHLPYLDEFDVIQATVTKLADDMNADGILAMTSSGNSARKMSRYRPKTPIYTFTHSKPVLGALTAFWGVVPVVSIKEAQAS------KMIQKMLRTLQKNKILNKNGIYIATIGYPVGPGSTNTIKILT. 467
211 0.000e+00UniRef50_A0A2D9KNE9 Pyruvate kinase n=2 Tax=Alphaproteobacteria TaxID=28211 RepID=A0A2D9KNE9_9RICK  ali  35  3..................RRTKIVTTIGPASCSKEIIEKFFDLGVNVFRLNFSHGKHEIHSNVVDIIRKIESE-KKRHVAILADLQGPKLRIGKL-ESSSINLVANQKISL---DLKSEIGNTQRIPFPHPEVMESLEIGHRLLLDDGKIELKVVDVSQ-SSLTAIVVVPGKISDNKGVNIPDTSLKRSPLTKKDLDDIEFIKKLDVDYIAQSFVQSALDVKSLKALVGD---QFKIVAKIEKPQALQDIDEIIKVADAIMVARGDLGVEMDLAYVPVAQKTLIAKARANFKPVIVATQMLESMISASSPTRAEVSDVANAVFDGADAVMLSAESAAGAYPCESVTIMDKIIKETESSQHHKVERDFIRC---ESITPSEAIAAAAYQLAENFQACAVVCSTITGATAMRVSHFRGYVPIYAMTPNLKTARSLSLVWGVTSYVCSEY------DQFDHLIKAVNTFILSNHIAQKGEKAIITGGNPVGVGQTDLIQVLEV 467
212 0.000e+00UniRef50_A0A1F6NY33 Pyruvate kinase n=2 Tax=Candidatus Magasanikbacteria TaxID=1752731 RepID=A0A1F6NY33_9BACT  ali  36  1.................MKRTKIVATIGPASASGKIISQMVRAGLNCARLNFSHGSHNEHRRLYRAIRVAGKKYHE-PVLIMADMRGPKFRLGNLR--VPVVLKINQKVVLAPESKTNEAG---VIPVDFFGLQKCLRAGERVLIDDGKIALKITRVSKDK-IFATVAEGGLVSARKGVNLPDSKLDMLSLTDKDKADLEFCIKLGVDAVALSFVHSADDIKQARALITKSGSPTKIIAKIENQSAVANMEKIIAVADGIMVARGDMGVELPAAQVPLVQKRLIDLCNAAAKPVIVATQMLDSMQEHIRPTRAEVSDIANAVIDHTDAVMLSNETAVGKFPALSVRTMAEIVMVTEASTYDDLPGAVIRKKGSQ---VDESIVQLSRLLAENVGAKLILAASLTGETGRMISHLRSEIPVLVATHDARVQRQLNLSWGVKPFILPVC------KTIEELIKKSMVYIKKEKFANKGDKMIVVAGEPVGAGHVNLVEVREV 476
213 0.000e+00UniRef50_A0A2H0BTH7 Pyruvate kinase n=1 Tax=Candidatus Uhrbacteria bacterium CG22_combo_CG10-13_8_21_14_all_47_17 TaxID=1975041 RepID=A0A2H0BTH7_9BAC  ali  39  2..............HIPEKRTKIVCTIGPASASPEIMEQLIHVGMNVARLNFSHGTHEEHAKLMETIRHSAKKLE-QPVAILQDLQGPKIRVGELPKEG-IELVKGEQVILSATTDTAE---NNVIPVSYPNLHKDVEAGQKLLFDDGKLSVTVKEIQGDK-VICTVLDGGTLLSHKGLNLPETDTKISGITEKDKSDLAFGVAQDVDFIALSFVRSADDVRQLRGLIEDEATPIRIISKIEKPQGVEHFDEILEASDAIMVARGDLGIEVPAARVPILQKDMILKCLEAAKPVIVATQMLESMTTSPRATRAEVSDVENAVIDHTDAVMLSGETASGLHPLEAVQTMVAAVKEAEKSHYDDL---AVPFSPDAEGSIAHLIAGAT-------NLVAALVVSVTGQAVRVVARYRPEAPILAAVQDERLARQLLLSWGVSAVVMQEQEESEALKKLKLFIQKAPDIAK................................ 447
214 0.000e+00UniRef50_A0A1V5SU79 Pyruvate kinase n=1 Tax=Candidatus Atribacteria bacterium ADurb.Bin276 TaxID=1852833 RepID=A0A1V5SU79_9BACT  ali  33  13..................RKTKIVATIGPSVSNPENIMKLIQEGVDVFRLNFSHGTLEEHFSVLQTIRNYDSQQKKFH-AVIGDLPGPKLRIGEIQGGET-ELPDGAVIYII---HSSLPGSMPVITVDNVELFTLLKPGDIFFINDGLVRLRIIS-NDNCTILCKVEKGGVISSRKGINIPYLPDSFPSLTTRDLQILEAIKDWDLDFLALSFVRGIKDILALRNRIANFSRPFSIIAKIEKPQALNEIDEIIEASDGIMIARGDLGVEVPVESVPFWQKRIIFESRCRCKPVIVATQMLDSMIRNPIPTRAEVSDVAGAIYDGTDAIMLSGETAIGDFPMESVQTASKIARFTE---YYADFVPDVQKIMVNNTDLSSAISFGAWEIARNLKLTVVVTSTYSGSTARRISRFRPNIPILAFSPQYHILRLLKLSYGVFPFSVDLCTEPS------KLIEEMKRLTLASRFGKKGDKIIITAGVPLKSGFTNFLQVEE. 479
215 0.000e+00UniRef50_A0A2E7G5K7 Pyruvate kinase n=2 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A2E7G5K7_9CHLR  ali  34  3..........NLISQVKIPKTKIICTLGPSTHTKSVITRLIKSGMSIARLNMSHGSFDSHKILIKNIKEISNNL-NIPIGIMIDIPGTKYRIGPLKN-SEYALFKGDNITITSNNV---KGDNKIISVHPNGIHKDIKLNATILIDDGLIKLKAI-KHNEKEIICKILNNGIIRPKKGITLPGLPTSLKFPGKKSIECLKFADQEMPDFIALSNITSEKDIAKAKSVLKNTQNKTHIISKIERPEALKNITSIIQISDAIMVARGDLGVEVPISKVPIIQKEIISQCNKNGKPVITATQMLESMIYSSTPTRAEVTDVANSIYDGTDAIMLSAETSIGKYPVEAVKVMSEIAHETEKVLPYEKIIMEKSHQTQSKSE--DTISYDACWSAYQLKAKLIVAFTESGTTASRVSRYRPPTKILALTPKENVQRKLTLLWGVIPVTVEKLFT------VDDFFNKALYESISKMNLKEKDLLILVAGLPIGPGGTNLLRIMTV 479
216 0.000e+00UniRef50_A0A0G1D7R7 Pyruvate kinase n=2 Tax=Parcubacteria group TaxID=1794811 RepID=A0A0G1D7R7_9BACT  ali  35  2..............HSMYRNTKIICTIGPATESQKMIEQLVKNGMNIARLNFSHGTHQYHKTLIQNIRVVSKRLH-QPVAILQDLQGPRIRIGILT--EPVEVVRNEKIIIVPESEFKKRGLGKILPVQYEELYKDLHKDSTILIDEGFIELEVVKIV-GSHIHAQVVTSGIVKTNKGINTPGKELSADPLTKKDRDDIRFGIEHGVDSIALSFVSCADDMVVLKKEVMKRGITPALIAKIERQAAMDDIENIIVESDAVMVARGDLALECSAAEVPVMQKRIVGACIRNAKPVIVATQMLDSMIENPRPTRAEVSDVANAVIDHADCVMLSGETASGSYPLEAVAMMEKIIEETEASPYDDAPREFARMFHMSGDR--HAIAEAAVDIAITEQASALVIASLTGATIRAVAQLRPAMRILGLVTEEALARQLIFSWGVNPLVIAKQQS------VGKLIEVCLSTLEKTKIAKKGDKIVLVAGQKVGPGTTNFVQVQE. 482
217 0.000e+00UniRef50_A0A2E8SGN7 Pyruvate kinase n=4 Tax=Bacteria TaxID=2 RepID=A0A2E8SGN7_9RHOB  ali  33  3............KQLHRNRKVKIVATLGPASDTKSEIKKMFLAGADIFRLNMSHGDHPAVEKRHKILRDLENEFS-RPICILADLQGPKLRCGEF-EGSKVRLEAGQKFCF---DLAKTPGNNQRACLPHPQIFMSVRKGDKLLIDDGKVALEV-RKXSEMNIECIVLNDGIISDKKGVNCPDSILDLAPLTEKDKEDLEFVCXLGVDWIGLSFVQRAKDVDDVKKLL---NGRAGIIAKIEKPAAVEVFDXIINSSDGIMVARGDLGVELPVEAVPPIQKRLVLKSRQMGKPVIVATQMMESMIHSTTPTRAEVSDVAQAIYDGVDAVMLSAETAIGAHPEKVIQAVDKIAIEIEKDPLYFENLENSRTNLKEG--VSNAITVAAREVADNIKVKVICCFTHGGTTAELASRERPRAPIIALTPYTETARKLTLFWGLHCVV------TTPVDRFKRAVMNAVKAAKLFEFASXKDLIIVIAGVPFNPGSTNILRVV.. 472
218 0.000e+00UniRef50_A0A2H0RNV7 Pyruvate kinase n=12 Tax=Bacteria TaxID=2 RepID=A0A2H0RNV7_9BACT  ali  36  8.............TPLAMRLTKIVCTIGPACRSAQTLKALCDAGMTVARLNLSHGTQDDCKTIIEDIRKINQDY-GYAVAIMFDTKGAEIRTGVVQ--YPIEITKGQEVVFSPHPLDNEE--RTVITVNYDRFYADVPETDRILIDNGEMALDIVDIRADGSVVARSQDDGSIGSRRHINLPGADIDLPSITEKDWEDIAFTCEQKADFVALSFIRNAGEVQSVRTFLEERGSPMQIITKVETRQAVENIAEIIDVSDAIMVARGDLGADLPFEELPIIQDDIVLRCRDRGTPVIVATHMLESMTEHPMPTRAEVTDVAYAVMTGADATMLSGETASGKFPIRAVEAMARIQQRTEEHI------ARFSRRAEPVHDEREGRSEAAVSLAQASKAVAIVAFTKTGRTVLEISKFRPSLPIIACTNTPERQRSLQLAYGVLPLCVP-------FADPETTVQNGFSCAKERGFLHDGDSVVILSDIPIDSGFAPSVQVRT. 476
219 0.000e+00UniRef50_A0A2E4J600 Pyruvate kinase n=21 Tax=Flavobacteriales bacterium TaxID=2021391 RepID=A0A2E4J600_9FLAO  ali  31  2...........IERKYRLKRTKIVGTIGPTSLSKKKIRKMILAGLNVCRINFSHCNHEDASKIISIVDELNTEL-NAHVAILGDLQGPKLRIGSVSNNNVIEKNQ-----LVSIQDGNEISNNTSIFVNYPNISNDIKVGDKILLDDGKIILKVDGV-DGIKINCIAIQGGKLHSNKGFNLPNTKISLPTITNKDYSDLLFSIENKIEWIALSFVRKGEDIVRLKKIIHEHGGRAKVIAKIEKPEAIKNLNSIISNSDALMVARGDLGVELPTQKVPVLQKKIVRASRKKAKPVIIATQVMESMITNLSPTRAETNDAANAVFDGADALMLSGETSIGKYPTRVIRTISKIILDVEAS-DERKHFNKYLPFKSNKRYISDSICYQASEIANQVEAKAILAFTASGYNAQKISSNRPNAHICVFTYNRQLLNTLSLIWGVLGFYYNKF------DSTDNTIQETQDILIDEKIIKSGDFVINIASMPIKKGMTNMLKLEKV 477
220 0.000e+00UniRef50_A0A2E5QHQ0 Pyruvate kinase n=13 Tax=Bacteria TaxID=2 RepID=A0A2E5QHQ0_9CHLR  ali  34  61...................KTKIVCTLGPSTSSVTKIKQLIKSGMSVARLNLSHGDNNEHKKLIKNARLASEEL-NFPLAILADIPGPKYRIGKINSGEYLELVKGSEIIF---ENQTNSPNSKSINIWPNGFTKNLKVGSKILIDEGSIEMRLLSVKENT-INCKVTSGGKLQSNKSITVPGHTQNIDYFSPETLDAIEFVKSSDIDYIGLSFIRNSKDLIEIKNKLKDMNKTLKLISKIEIEQAIENLEEIICNSDGVMVARGDLGVEIPFEKVPELQKRIIKMANTYGKPVITATQMLESMIEKPNPTRAEVNDVHNAVIDGTDAVMLSAETSIGNHPIKAVKAMAKIAKTSEKYLDKISIANRKSNFIHNNNDVDDAIALSSCNLSNSIKSKGLFAFTESGSTASRVASFRPNASIIALCSTYDVCKNLSLNWGIIPIKVKSLSR------VQDMFREGSKIAIETGIGKIDDLIVIVLGLPIGPGNTNLLRVIK. 531
221 0.000e+00UniRef50_A0A2P6GIF7 Pyruvate kinase n=2 Tax=Alphaproteobacteria TaxID=28211 RepID=A0A2P6GIF7_9RHOB  ali  34  9..................RNVKIVATLGPSSSTEEMVSRLFEEGVDVFRLNLSHGLHDEIKKRHEIIRKVENKFR-RPICIXADLQGPKLRCGDF-KDKQAELVTGQTFVFDKERAL---GNSKRVYLPEFEVFKSLKKDSKVLVNDGKIKLVVKEVSEN-FVSTEVLVGGIISDKKGINVPXQLLPLSALSKKDLSDLEFVCNLGIEWLGLSFVQRAKDIKEAKKIVR---GRAAILSKIEKPSAVDAFDEILEETDAVMIARGDLGVELPIETLPPIQKRLVRQCRDSGKPVIVATQMMESMINSPVPTRAEVSDVAQAIYEGADAVMLSAESAVGNYPIEAVXTMNSIATEVEKEKTYRQLIESSR--TPLKGDVSDAITVAAREVAETTNVKVICCFTETGTTASLTSRERPKVPIIALTPKITIARRLTLNWGLHCIVTEELERFKMA------VVNAAKAARMYGFANNDDKIIVIAGVPFNSGTTNILRV... 471
222 0.000e+00UniRef50_A0A2H0CQD6 Pyruvate kinase n=1 Tax=Nitrospinae bacterium CG22_combo_CG10-13_8_21_14_all_47_10 TaxID=1974050 RepID=A0A2H0CQD6_9BACT  ali  38  3.................IRLTKIIATLGPASGSKTIIRNLVAKGVNIFRLNLSHGDHETVRQWIHWIREVEKERHTFT-GILLDLQGPKIRVGKFEKG-SILLKRGQKVIFTTAKTM---GSSSLVHVQYARFHQEVGVGNRIYLDDGKLSGVVKGI-SGQRVKVEMLVGGTLSDHKGLNLPDAQLSANPITAKDKADLKFGLQEGVDMVALSFTGSAKDVRQLRAMIKEGGKGVEVIAKIERKQAVANLEEIAEAADGIMVARGDLGIEIPLTEVPVVQQKILRQGARHAKPVIVATQMLESMIENPRPTRAEVSDVAGAVMDCADAIMLSGETAVGKHATAAVGVMVETALNTEAYLAESRMIEPWNRFFQGDPNINEGITYSANRMVELLRAKAMVVFTISGGTAKMVACPKPMVPVFAFTSNLKRARLLSLVRGAVPFLVKDDRHLLLHMD------QMIAMLKNKGLVKKGDRVVITTGIPVDPNWTNVIRVEEV 475
223 0.000e+00UniRef50_A0A2A5X5U9 Pyruvate kinase n=16 Tax=Bacteroidetes TaxID=976 RepID=A0A2A5X5U9_9FLAO  ali  33  2...............KPIKKTKIVATLGPSCDEQNIIEKMILAGVNVFRVNFSHAKYEEVEDRIKKIRQADKKL-NTQSAILADLQGPKLRVGKMEEGSVVH--PEDEVVFST--QAPFVGNAQKAYMNYQQFPKDVTPGEKILLDDGKLIFEVISTDKNTEVTTKVLQGGPFKSNKGVNLPNTNISLPALTEKDVKDAEFIFTQDVDWIALSFVRHSEDVLMLKDLMKKHDKPLPVISKIEKPEAIENIDKIIAYSEGLMVARGDLGVEVPVAEVPLLQKELVLLSKKARIPIIIATQMMETMTESLTPTRAEVNDVANSVMDGADAVMLSGETSVGKYPVEVVETVRTIVMQVENS--KRVIVPQDPPNIRTKRFITKSVCFHAAQIATDIKANAICTLTNSGYTAYQISAWRPISNILVFTSNKRILTQLSLLWGVKAFYYDNFQS------TDNTVEEINAIAHQKGYVREEDLVVNLTAMPIKKGMVNTLRVSVI 475
224 0.000e+00UniRef50_A0A1V5T684 Pyruvate kinase n=2 Tax=Bacteria TaxID=2 RepID=A0A1V5T684_9BACT  ali  33  2...............PFSNRTKIVATIGPASNSRRVMRAMISAGADIFRINGAHGDSKEHKEVIDLIRSVAKSMK-APIGILFDLPGPKIRLGELLQE-SVQLKKGRNVVLVCGKQRAPAG---QIPVQDKFVARAVKSGSRIFINDGIVELEVMKVY-GSYIECKVIVGGEIRSRKGINLPNIKLPIPTLTPKDRKLLDFAIKNEVDYVGLSFVRNAANVKYMKNLLARRAPEIGIISKIEKPEALLELKEIIKLSDAVMIARGDLGVEMPFDKIPTIQKMIIESCRALCKPAITATQMMESMVSSLRPTRAEATDVAMAVWEGTDAVMLSEETSIGWNPAKAVSAMARIALEAERNIPQSSYPEPKQEKKELQGQV---ISYASAVVADEISAKAIVTPTRSGRTALFISSARPRSPILAPTQHESVARRMNLYWGVVPLIMPPFNT------VDEMLSHAEKVAIRSRFIKKGDSIVIVSGAHGKKDDTRLLEIRTV 473
225 0.000e+00UniRef50_A0A2N1RAR1 Pyruvate kinase n=9 Tax=Bacteria TaxID=2 RepID=A0A2N1RAR1_9SPIR  ali  37  5..................KLTKIVATISDTNCDPAFLRSLYEAGMNVVRLNTAHQTPEASARVVANIRAVSET-----IGILVDTKGPEVRVRGL--EEPLVLKTGETVTI-----PKVDEVRKGFSVSYEGFVDEVPLGSRILMDDGTIELVVKHVANG-MLLCEVLNDGTLKDRKSVNVPGVPLRIPALSEKDRAYLKFVADNGIDFVAHSFVRNKEDVLEVRRILDGYGSKARIIAKIENIQGVTNLPEILDFADGAMVARGDLGVEIPFERLPGIQKTIIEACVRKGKPVITATQMLHTMIENPRPTRAEVSDVANAVFDGTDALMLSGETAFGKYPLESVRTMARIAMQAES----QKPRGESMISEATPNRVRDYLARSVALSALRLPIKAIIADTESGRIARLISSYRSHVPIYAFSPQMSTVRSLSLTFGVFS------EQSDAAHTTDQLVSHSLERLVARGAIETEDLVAIIGGSPGQSETTNFLEINT. 462
226 0.000e+00UniRef50_D3RWQ1 Pyruvate kinase n=1 Tax=Ferroglobus placidus (strain DSM 10642 / AEDII12DO) TaxID=589924 RepID=D3RWQ1_FERPA  ali  35  1.................MRKTKIVATLGPSSESYEVIEKLVQAGMDVARINMAFGSRRYHSKLIEAVREASEEVR-RNVAILGDLSGAKLRIGELK--KPLTLHRGESVVIV-----KSESGEDAIPVPHSEFFERVKAGEIIHLADGSIKLRVIEV-EKSKVVAEVIEGGVLTSYKGISFPG--LCRVGLTKKDIRDLEFLLGKEVELIALSFVTSKEDVLKLKELAEE----TAVIAKIERREAVENLGEIVKASDGIMIARGDLGVEVSIEEVPVIQKRAIKLANEEGKFAITATQMLKSMVVQKEPTRAEVTDVANAVLDGSDALMLSEETASGNYPVEAVKIMDRIIRRAESIYHYLQ--------ERSVRSVTEAIAYSAARISEELKAEAIVVFTRTGSSAIQISRFRPRAKILVVAHDKRTLRKSSIVWGCHPL-----CSVPPKGNVDELISEAISTAVERKLVKKDSLVVVTSGMPFGPGTTNTIKVLRV 456
227 0.000e+00UniRef50_A0A2F0ASM9 Pyruvate kinase n=1 Tax=Myxococcales bacterium TaxID=2026763 RepID=A0A2F0ASM9_9DELT  ali  37  1.................MRKTKIIATIGPATSSRDMLSKLFDAGCSVVRINMSHSSQDEAAQIIASVRSIS-----TRVGILLDTRGPEVRTTEV--DSEIELVAGREVIIRGEE---GPTTTEIVRVNYSGFHRSMEAGSTILLADGRIQLEVLA-ASNEQLHCQVVAGGALGSKKGVNVPGVKLPMPFLSDQDISDIQFGVAQKVDFIAASFVSEPEDVLRIRELVAEEGGRVSIISKIEARYAIKNLADIIAVSEGIMVARGDLGVEIAAEEVPVVQKQMIDACRGAGKVVIVATEMMESMIHNPRPTRAETSDVANAVFEGADAIMLSAETSVGAYPTEAVATMARISKEAEVARRQKTWPGDRRAH-----NISDIMCKGAWLAARELNMQAILVPTSTGRTARRMSRYRPAVPILVTTPDMAVARGLALNFGVYAL------STRHYGRMENMIRRSCQVMVNETWLSEQDLIAVVCGVPVGSGNTNLMTLQHV 464
228 0.000e+00UniRef50_A0A2D9JJJ7 Pyruvate kinase n=7 Tax=Proteobacteria TaxID=1224 RepID=A0A2D9JJJ7_9GAMM  ali  31  12..................RRTKIVATVGPASADEECVAALIDAGVDMFRLNMSHGDQEGHADVFHRIRRAA-DNAGRAVAILADLCGPKIRVGHFANGG-IDLIDGEPVTITVRDVDGAPG---LIPSQYDARADDLEVGARVLLADGVMELKVLAV-EGTEVRCEVVQGGHLTARKGINLPDVRVSAPSLTPKDRSDAQFALSLGVDYLALSFVRSAADLNELRTLVDAHPHAASLIAKIERPEALQDIDAIVEAADAIMVARGDLGVELPPEQVPAIQQQLVDRARIYNRPVIIATQMLESMIENARPTRAEVTDVSHSVFVGADAVMLSAETAAGAFPVEAVQMMDRIARQAEAHLWRQEGFESLRELNDDTLTFGDAIARAMSTMSRDLGVRAVVTFSESGMSALTMSAARPAAPIVAVSSNAATSRRLALCWGKLPVEVD-------MDDLDHQPQIARQLVHDAGLSQRGQYLLMVKGFHSDPKSTPTITLLK. 481
229 0.000e+00UniRef50_A0A2R6J7G4 Pyruvate kinase n=1 Tax=Halobacteriales archaeon QS_5_70_15 TaxID=1919180 RepID=A0A2R6J7G4_9EURY  ali  34  21............EDTNRVRNAKIVCTLGPASDDAETIEGLVEAGMSVARLNASHGTTEHRAELIDGIRRVDATAEGT-VAVMLDLQGPEVRTAPL--DEPIDIADGSTVRFVQGDTA----TPEEIGLSTS--IAAVTPGDRVLLADGRIETTVTEV-DGETVYARVDSGGPLGGRKGVNVPRVDLGLETLTDRDRRELELAVEKGVDFVAASFVRTGEDVYGVSQTMEELGASIPVIAKIERADAVENLDDIIDEAYGVMVARGDLGVECPLERVPIIQKRIIRKCVNAGAPVITATEMLDSMVEERRPTRAEATDVANAVLDGTDALMLSAETAVGEDPVTVVETMDRIVRDVEGSEEYAEVFERMVPATGGTQ--TDALARSARYMARDIGASAVVAATESGYTALKAAKYRPTIPVVASTPNDGVRRRLGLSWGVVPKYTPMTSGGA-----EAVIQEAVQTALEAGVADSGDTVVALAGMMTGVDTTNMLKVHV. 493
230 0.000e+00UniRef50_A0A0S8JSV8 Pyruvate kinase n=1 Tax=candidate division BRC1 bacterium SM23_51 TaxID=1703761 RepID=A0A0S8JSV8_9BACT  ali  32  1.................MTQTKIIATLGPASDSHAVVRALIEAGADIFRINFSYGQPDEHRRLARTVRAVAGEMS-RDVALLGDVAGAKLRCGRVDPD-PLSLEVGSEVTLVGEDV---AGSESLIPVTYGDLHEDLRVGEAVALDDGRIRLRVEAI-EGRRVVCRVVEGGLLRSHKGINLPETGLRIPAITDDDQRSIALAVEEGFDFLGLSFIGSARDIITARSIVHQHGADMALIAKIERRAAVENLDEILDAADGAMVARGDLGVELPIERVPLVQKQIIRACNERAKPVITATQMMESMVHNRRPTRAEVADIVNAIFDGTDAVMLSGETAIGAYPVETVRAMDRVAQAADEALDREGHLRRGESGPSPDND--AAIGRAASEIALDLKLDAIVCLTEGGSTPRRIARHRPRCPIVAVSANSTTGRQLLLSWGVQPVVLAELADLAVGADMASQMRRILGLCVRVGSLRAGQRVAVVAGLPLDPGITNLIHLTVV 489
231 0.000e+00UniRef50_A0A2I3HAM0 Pyruvate kinase n=5 Tax=Bilateria TaxID=33213 RepID=A0A2I3HAM0_NOMLE  ali  44  34.TFLEHVCHLDIHTPPTAWNTGIICTISPASRLVEMLKEMIKSGMNVACLNFSHGTHEYHVETIKNVCTATESFAYWPVALALDTKGPEIRTGLIKGSTEVGLKMGAILKIMLDNAYMKKCDENILWLDYKNICKVMEVGSKIYVDDGLISLQGKQKGAD-FLVTEVENGGSSGSKKSVNLPGAAVDLPAVSE-DNQGLKFGVEQDVDMVFASFICKASDVHEVREALGEKGKNIKIINKIENHVGVRRFDEILESSDGIMVAGGDLGIEIPAEKVFLAQKMMIGP----GKP-IC------------------DSDVANAVLNRADCIMLSGETAKGDY-LEAGRMQHLIAHEAEAAIYHLQLFEEL-------LDPTKATALGANEAFFKCCSGAIIVLTKSGRSAHQLARYRPRAPIIAVTWNPQTARQAHLYRGIFPVLCKGLVQEARAEDVDRWVNLALNVGKAQGFFKKGDALIVLTGWCPGFGFTNTVRVVPV 511
232 0.000e+00UniRef50_A0A2P5LAQ1 Pyruvate kinase n=50 Tax=root TaxID=1 RepID=A0A2P5LAQ1_9PROT  ali  33  2................TLRKTKIVATLGPSSTSEEMLARMITAGVNVVRLNFSHGSAEDHIKRAEIVRNIAIKL-GRPVGVLCDLQGPKIRIGKFELGK-ITLKTGDIFILDAD---CELGNQYHVGLDYKTLPQEVSENAILLLDDGRITMQVDRI-KGNQIHCVVLSGGVLSNNKGINRQGGGLSAEALTKKDREDIKTAVALEADYIAISFPKSALDVELARTLVRKAGGTASIIAKIERAEAINDLEAIIDASDAIMVARGDLGVEVGDAAVPGLQKRMIRMARAQNKLVITATQMMESMITSPIPTRAEVSDVANAVLDGTDAVMLSAETAAGQYPLETVEAVHRVAIEAEKEYFSQHHAQKL---DQVFIKTDEAVAAAAIYTAQHLKVKAIAALTQSGNAAQWLSRADAEVPIYALSPDKLARRKLTLHRGVYPYPIEQA-----DKNRDEIIAEMEQVLLRQRVVAEGDLVLLTFGEPIGPGGTNTLKIIKI 472
233 0.000e+00UniRef50_A0A1Y4DGK2 Pyruvate kinase n=1 Tax=Elusimicrobium sp. An273 TaxID=1965617 RepID=A0A1Y4DGK2_9BACT  ali  32  9.....................KIVATIGPDTSNEKAIEQLVLAGVSVFRCNCSHGSLPEYQERVTNIRKMEKKY-NCTLGILFDLQGPKLRIGTF-KDYRITLKEGDKFRLDMNP---EPGDQTRVCLPHKEIFAAMKDGLELLLNDGVVRLRVDAHTADTA-DCTVIAGGELSNKKGVNVPGVKLPLSALTAKDKEDLKIAEMLGADFIGLSFVQEPEDIIELRSLMKSK---AHIIAKIEKPSAIEHLREIIDLTDVIMVARGDLGVETSPELVPVLQKKIVSGCRKAGKPVIVATQMLESMIHNVMPTRAEASDVATAVYDGVDAVMLSAETAQGDHPYEAVATMRRIIETVEKDHRYRKGLSTLERKNDSTKE--GAITSAASLVATNMDANVIVTFTDSGSTTLRASQQRGGLPILALTPNITTARQLAVVWGVTPIVIEN------LKNFDDMTAETKKAVLAQKLAKEGDNVVVTAGIPFGAGTTNMLYVMNI 473
234 0.000e+00UniRef50_R6HDE0 Pyruvate kinase n=18 Tax=Clostridiales TaxID=186802 RepID=R6HDE0_9CLOT  ali  39  2...............KHLRKTKIVGTIGPASENK--LEELFAAGLNVTRVNYSHGSWDEQSEKTENIIRLRKEL-DIPVALLLDMKGPEIRTGMLYTGKKIQLKDGQKFTLVNDDI---EGNEERVSVTYKELYKDVETGTKILIDDGAIELKVDEVV-GKDIVCTVVHGNGLGSRKTMNLPGTVIRLPGLAEKDIADLKTACEHDYDFVAISFARNLDDIRQVRKVLDENGKDIQIITKIENVEGISNIDDILKEADAQMIARGDMATETDFTEPPVIQKRIIKTSNELCKPAITATQMLESMTHQPLPTRAEASDVANAIYDRTSAIMLSGECAQGDYPVECVQTMVKIANRVEPEINYWKRFDESENI--KLDDLEANISYSACVIAKNIKADAILCYTNTGKSARRLAGMGAGCPILAITDNRRTFNQLALAWNVTPVYVEKE------ENIEATIEKGIEKLQNKEILEKGDLLVVVGG................ 458
235 0.000e+00UniRef50_A0A069PYA5 Pyruvate kinase n=511 Tax=Bacteria TaxID=2 RepID=A0A069PYA5_PSEAI  ali  34  3.................VRRTKIVATLGPASNSPEVLEQLILAGIDVARLNFSHGTPDEHRARARLVRELAAKH-GRFVALLGDLQGPKIRIAKFAN-KRIELQVGDKFRFSTS-HARDAGTQEVVGIDYPDLVKDCGVGDELLLDDGRVVMVVEEVAAD-ELRCRVLIGGPLSDHKGINRRGGGLTAPALTDKDKADIKLAADMDLDYVAVSFPRDAKDMEYARRLLTEAGGKAWLVAKIERAEAVDALDGLIRASDAVMVARGDLGVEIGDAELVGIQKKIILHARRNNKVVITATQMMESMIHSPMPTRAEVSDVANAVLDYTDAVMLSAESAAGEYPVEAVKAMARVCQGAEK---HPTSQKSSHRLGQTFDRCDESIALASMYTANHFGIKAIICLTESGFTPLIMSRIRSSVPIYAYSPHRETQARVAMFRGVETIPFDPAALPA-----EKVSQAAVDELLKRGVVTKGDWVILTKGSYTAQGGTNTMKVLHV 478
236 0.000e+00UniRef50_A0A0Q9WRH2 Pyruvate kinase n=33 Tax=Pancrustacea TaxID=197562 RepID=A0A0Q9WRH2_DROVI  ali  45  1............................................MRVARLNFSHGSHEYHCQTIKAVREAVNCYAQKPVAIALDTKGPEIRTGQLSGSAEIELKQGDKIKLSTNKSLEASGSKDAIYVDYPKLPKIVKPKNLIFIDDGLISLIVKEV-SGEEVVCKVLNGGKLGSRKGVNLPGIPVDLPSISDKDVCDLQFGVEHDVDMIFASFIRNAKALAEIREVLGPKGKRIKIISKIENQQGMQNIDAIIAASDGIMVARGDLGIEILTEEVVLAQKSIIAKCNKVGKPVICATQMLDSMIGKPRPTRAEASDVANAIFDGADCVMLSGETAKGKYPVECIKCMANICAKVENVLWYEHLQNDLRSSMKASMDNISAITSGITEIATLGHANAIVIASPSPVVAQLVSQFRPKCPIVFLTGSPRRARQTIIFRGVYPIVPEEMVNG--CKDFARILTAGIEEMTKMQIV........................... 434
237 0.000e+00UniRef50_A0A0G4HPT6 Pyruvate kinase n=1 Tax=Chromera velia CCMP2878 TaxID=1169474 RepID=A0A0G4HPT6_9ALVE  ali  32  64.SRLESSANMSEDSLSRFRRTKQVATLGPASSTFEMIEKLFLKGVDVFRLNFSHGKREDKEALVKTVRDVEAK-WDHPIALLADLQGPKLRVGVFEHD-SVVLQEGQTFSF---DSSSDPGDACRVQLPHPEILKTLRPGDVLLLDDGKLKMRVKRTSTQKEDEGGSETGGKLSSRKGVNTPTVVLPISAMSEKDRLDALYAKKIGVDWIALSFVQRPEDVQELRELV---GVGPKLLAKIEKPSAVDCIDDIIAVSDAIMVARGDLGVEMNCEDVPVIQKQIVDKCRKEGRPVIVATQMLESMITSPTPTRAEASDVATAIYDGADAVMLSAETAAGQYPVEAVKVQQRILHRVESDANYQIGIDAKVAADRHHRDATDSLTMAAKHIAETIDARGIVVFTLGGTSAIRASMGRPHKPILAITPDIRVARRLQLYWGVYPV-----ADTQTVGSVEEMWQRACDVAVQEGIARPEEQVVITAGLPFGPGATNNLRVCQ. 582
238 0.000e+00UniRef50_F0W1S6 Pyruvate kinase n=7 Tax=Oomycetes TaxID=4762 RepID=F0W1S6_9STRA  ali  41  53................KFSMTKIVGTIGPVSESPDMTQKLVDEGLRIMRINFSHAEHSEALQRIHNLRASESQNTFNLRAVLLDTKGPEIRTGKMKNGKKVLLETGKEIILTNNKEFQDQGTAERIYITYPHLVNTVKSGDTVLLSDGLIRLNAIHVDKKNEIRCVIKNTEELGNTKGVNLPGLKVDLPALSEKDKVDLMFGVQHDVDFIAASFIRKPSDVIEIREFVQSQMSKPKIISKIENLEGIQNFDQILEVSNGIMVARGDLGVEVPLQKVLTYQKSMVEKCNAIGKPVIVATQMLESMIQNPRPTRAEVSDVGNAVLDGADAVMLSGECANGKYPVESVRTMMTVIKEADELLETHYHEYE---WTPAENDV-ESVASSVVKTAHEMKAKLMIVLTDTGRTAQMIAKYRPTVPVMCFTPSCKIGRQLQIHRGLYPVVPANQASRPTA-------AEAIKEAKRMGWLVSKDRVV.................... 519
239 0.000e+00UniRef50_D8LP24 Pyruvate kinase n=56 Tax=cellular organisms TaxID=131567 RepID=D8LP24_ECTSI  ali  33  121..................KNTKQIATLGPASCTEEQIEALFLAGVDVFRLNFSHGDHDQKAELVSIIRVIEAKYK-HPICILADLQGPKLRVGTFEHDT-VNLVNGQMFRFDMDD---EPGDAARVKLPHKEIIDTLQEGDSLLLDDGKLRMTVVESGEG-YVICRVDVGGKLSNKKGVNTPTVRLPISAMTPKDRADLDFAVPGGVDVVALSFVQRAADVEELKDIVQ---GRCRVMAKIEKPQAVDDLEDIVALCDAIMVARGDLGVEMPPEMVPITQKQIIDCCRRQGKPVIVATQMLESMIDNPTPTRAEASDVATAIYDGADGIMLSAESAAGKYPLESVRMQQKIITSVEVDPLYRRYLLS-QAEKQKTGSATDAITRAARQVADTLCAKAIVVFTSRGTTVNKAAQLRPSVPVMGVTPNIETARGLALTWGVYPAVIEPDSDDV---NFRMMLFKCCAVAQAKLIAKPTDLLVVTAGLPFKPGVVNILRVL.. 591
240 0.000e+00UniRef50_W4M6M4 Pyruvate kinase n=4 Tax=Candidatus Entotheonella TaxID=93171 RepID=W4M6M4_9BACT  ali  35  137.................LRRSKIVCTIGLATDSEERLAQLLDAGMDVARLNFSHGEHAWHRLVCERLRRLSDQ-----VAIMGDIQGPKIRIGRMQEDRTVFLDPGATFVLTSRP---LEGDANIVSLDYPSLPQEVKPGHDLYLNDGLVALRVEEVIDGTDIVTRVLHGGPLTSRKGINAPRVQLSATVPTDKDRRDIELAVALDLDFLAVSFVTGAADLERVRGVVHEAGGHIPLISKIERAAAIDNYKEIMDASDGIMVARGDLAVEIPTEDVPYHQKDFIEQCNQAGVPVICATQMLESMTVSPVPTRAEVNDVFNAILDGADAVMLSAESASGAYPIETVQLMSRIVTNAEASLPPQEFDIRDTAGTPYFEVIGHGISTMVRHMSRGDHISAIVAITREGYSARMLAKYRPGVPIIAATHDPRVARQLMLSRSVKPMLLDNTLADPSTVT-----QMAILQALREGRVRVDDIVLTASGSSWAPQHTNFI..... 603
241 0.000e+00UniRef50_C1E515 Pyruvate kinase n=14 Tax=Viridiplantae TaxID=33090 RepID=C1E515_MICCC  ali  43  38..................KKTHIVCTLGPSSRTVDDLEKLLYAGMSVARFNFSHGTHEYHLESLTNLRQAC-VNTGKVCAVLLDTKGPEIRTGTLKDGKPVSLVRGKELTLTTD--YSVVGDENQIAVSYQWMARDVKCGDNILMADGSVMLEVLSTDDAGTVRVKCLNNATIGERKNCNLPGVAVDLPTLTEKDLHDIIFGVVHDVDFIAASFVRKGSDVLKIRDVLDNAGGSIRIISKVENHEGLCNYDDILRLSDGIMVARGDLGMEIPLERIFWVQKMMIRKANLSGKPVITATQMLDSMIAAPRPTRAEATDVANAVLDGTDCVMLSGETAAGAYPREAVEIMAGICEEAEQCVDNWALSQALLNSTMSPLSTIEALASSTVMTAAKVKAACIVVLAANGDAARMIAKYRPAVPIVVGVRGQQVARQLMVTRGLIPVVVSKELDALNSMDDEAMVMAAVRHARQQMLCRPGDKVV.................... 537
242 0.000e+00UniRef50_A0A2U3CFB6 Pyruvate kinase n=1 Tax=Candidatus Heimdallarchaeota archaeon B3-JM-08 TaxID=2012493 RepID=A0A2U3CFB6_9ARCH  ali  37  4....................TKIVATIGPASDNILVLKDLLKY-VDVCRLNFSHGAYPDHLERYERIRSVSKD-----VAVLVDLCGPKIRTGDVEKDTF--LNTGQEFRIS--GKIGLEGNSQIVSTNYPPLIIDAKIGNHLAIDDGLLQFRILKKDKKNELICEVLNGGVLKSRKGINAPDVPLSIYFPTQKDFDDIRFVLDQPADYLAASFVRRKEDILVVREKLDEANSSMNIISKIENQDGLQNFDEILEVSDGIMVARGDLGIEIPSEKVPIVQKQIIAKCNKASKPVIVATQMLESMTINPRPTRAEVSDVSNAIMDGADAVMLSGETAIGKFPVETVGYMERIINEI---GQNLHLISTEPSWTTDSPNIPEVLGRAVHLIASSLGINAIVTSTRSGSTTRMIAKCRPEKKIIAGTPYETVKRQLQLVWGVYPLCVKVTPS------YDELLYEIVLAATEQQMLDAKDTILAVGGSMLGPSKTNQLQILNV 471
243 0.000e+00UniRef50_A0A1T2L532 Pyruvate kinase n=2 Tax=unclassified Gammaproteobacteria TaxID=118884 RepID=A0A1T2L532_9GAMM  ali  35  13.................WRRTRIIATLGPATSKRATIEQLMRAGVNVIRLNLSHGSHDEHRKSFARVRAVAKKL-DLHVAILMDLCGPKIRVGHFKNGA-ITLKQKQIITVTTRECI---GEGSLIPSRYARLHRDVKSGARILLDDGNLELKVLSV-EGRDVKCRVVTGGLLKDNKGMNLPDSDLSVPALTKKDREDAKLAAELGADYLALSFVRSAGDIRSLKKHLKRLGNEIPVVAKIERPEAVEQIDKIIEATDAIMVARGDLGIELPASKVPLIQDRLIEIARNKQKPVIVATQMLESMITNPRPTRAEVGDVAHAARSRADAVMLSGETAVGAYPLKAVQTMDEILREIEQSQRCQDHHNDQPIKHDHHDDSPAAVSHAVTSLSRDLDLQAIIIPTHSGTTARVLSADRPTSACLGVSSNERVVRRLALHWGIVPVQIDEDEAHDWH-------KLSRTIAARFKIQKRGSVVLLVSGFSDDP........... 473
244 0.000e+00UniRef50_A0A1M6CD30 Pyruvate kinase n=1 Tax=Parasporobacterium paucivorans DSM 15970 TaxID=1122934 RepID=A0A1M6CD30_9FIRM  ali  38  1.................MRKAKIICTLGPSTDNEEVLRQLILNGMNCARLNFSHGTLADQKKRIDLVKKLRAELK-SNVSILLDTKGPEIRLKDFEQGKA-ELVEGGIFTLSPD---VGLGNQLKASISYPGLAEHISLGTNILIDDGKVSLKVEEIR-GHDIICRILVGGVVSNHKSINIPGISIPMPYINAVDYEDLIFGIKNEVDFVAASFIRNEEDVMDLRRILDDNGGNICVISKIENEAGIQSLSKIIAVSDGIMVARGDMGVELPFIQLPAIQKNIIHRSIRHGCHTITATQMLESMTTNPTPTRAEVSDVANAIFDGSTAVMLSGETAVGRYPVEALVTMSKIVENAEANVDYKEFAED--NPIVFKNDIAHTIAQIACVAAANLNAKAIVVLTRSGKTATLIANYRPTCTIIAAVVNPVKMRHLSLTRAVHAINVPEQLSS------DSLFSYAQEIAIGTGMIEKGDKIVIVAGSSTSAKASDMLKVLTV 471
245 0.000e+00UniRef50_UPI00048A0A91 pyruvate kinase n=1 Tax=delta proteobacterium PSCGC 5296 TaxID=1286374 RepID=UPI00048A0A91  ali  35  1.................MKNTKIIATIGPASRDQSTIEKMAKAGMNVCRLNFSFGTHDEHLETISIIRKASKK-TGIPIAIMQDLQGPKIRVGKLN--SPVTVKEGQELILSGNTKHNE---EFYIPTTYSQIASDTKKDKKILLADGKIILKVLNTNSKKEVRCKVIEGGTILTGKGINLPYTNISLPCLTEKDIKDAKFGAKAGIDYMSLSFVRKAKDVEALRKLLKDQGKNLPIVSKIEKPEAVDNIDAIIDATDAIMIARGDLADEVSFAKVPLIQKKIVAKANKKGKSTIIATEMLGSMVDNQLPTRAEVSDVANGVLDGADLVMLSNETAMGKYPVKAVKMMAQIAEEAESTFEGEDFYREL--DLPKIHGQRELLCSAASFMSYDLKNDNIVVFSLTGLTAKILSKFRPEATIFAATYKEEVYHKMAFYNNVYPLLINKKDSIQFIPSMEE-------KLRKMKLINKGDTLIFLTAERINNTWTNSIKV... 469
246 0.000e+00UniRef50_Q7P1G4 Pyruvate kinase n=432 Tax=cellular organisms TaxID=131567 RepID=Q7P1G4_CHRVO  ali  32  2.................LRNTKILATLGPSSSAPEKILELARSGVNIFRLNMSHGSHDDHRARLAAIRAAEKTL-DRPIGVLVDLQGPKLRIGKFPQPTTV--KTGDRYEFVLDE---TEGNAERATLPHPEAFEALEPGHLILVNDGKLAFEVAEMHP-RRIVTRVTVGGELSSNKGFNLPHTVLPLSAITGKDRKDAEFALEEGADWVAMSFVQTAADVKALRDIV---GKRVGIVAKIEKPSAVDDLEAIAELADGVMVARGDLGVELPPEDVPVVQRRIVHHCRHLGRPVIVATQMLESMITAPTPTRAEANDVATAVYEGADAVMLSAETAAGQYPLEAVQIMDRIIRRVENAPDYRKVM-ALDYSAADEPDRTDAIAACVRKVSTLLPVTVAVAFTTSGASCLSLARERPSTPILGISPRLETARRLTLVWGVVAYHGPD------AENLEDMVVKTTFCATKLSLAEQGKPMVIIAGVPFGPGSTNLLRIV.. 466
247 0.000e+00UniRef50_Q9FLW9 Plastidial pyruvate kinase 2 n=59 Tax=Eukaryota TaxID=2759 RepID=PKP2_ARATH  ali  35  105.............KPTVRRKTKIVCTVGPSTNTREMIWKLAEAGMNVARMNMSHGDHASHKKVIDLVKEYNAQTKDNTIAIMLDTKGPEVRSGDLPQ--PIMLDPGQEFTFTIERGV---STPSCVSVNYDDFVNDVEAGDMLLVDGGMMSFMVKSKTKD-SVKCEVVDGGELKSRRHLNVRGKSATLPSITEKDWEDIKFGVENKVDFYAVSFVKDAQVVHELKKYLQNSGADIHVIVKIESADSIPNLHSIITASDGAMVARGDLGAELPIEEVPILQEEIINLCRSMGKAVIVATNMLESMIVHPTPTRAEVSDIAIAVREGADAVMLSGETAHGKFPLKAAGVMHTVALRTEATITSGEMPPNLGQAFKNHMS--EMFAYHATMMSNTLGTST-VVFTRTGFMAILLSHYRPSGTIYAFTNEKKIQQRLALYQGVCPIYME------FTDDAEETFANALATLLKQGMVKKGEEIAIVSGTQWRSQSTHNIQVRKV 579
248 0.000e+00UniRef50_Q8S7N6 Pyruvate kinase n=17 Tax=Viridiplantae TaxID=33090 RepID=Q8S7N6_ORYSJ  ali  33  81..........QVVSANSRRKTKIVCTIGPSTNTREMIWKLAETGMNVARMNMSHGDHQSHQKVIDLVKEYNAKNTGNVIAIMLDTKGPEVRSGDVP--EPIMLEEGQEFNFTIKRGV---STKDTVSVNYDDFINDVEVGDILLVDGGMMSLAVKSKTADT-VKCEVVDGGELKSRRHLNVRGKSATLPSITEKDWEDIKFGVENGVDFYAVSFVKDAKVIHELKDYLKSANADIHVIPKIESADSIPNLQSIIAASDGAMVARGDLGAELPIEEVPLLQEEIVRTCRSMQKPVIVATNMLESMIDHPTPTRAEVSDIAIAVREGSDAIMLSGETAHGKFPLKAVKVMHTVAQRTESSLYNPAHPQALLNEEFSQSQLSKMFGSHATMMANTL-CTPIIVFTRTGSMAVLLSHYRPSSTIFAFTNEERVKQRLALYQGVVPIYMK------FSDDAEETFSRAISSLLNAQFVKEGDYVTLVSGVKWREESTHHIQVRKV 568
249 0.000e+00UniRef50_A0A2A2FEP8 Pyruvate kinase n=23 Tax=Halobacteria TaxID=183963 RepID=A0A2A2FEP8_9EURY  ali  36  1.................MRNAKIVCTIGPASDDRDAIRDLADAGMSVVRLNASHGTTAHREEVIERARAVDDEIDD-PLAVMVDLKGPEVRTAEL--EEPIQLATGSEVTFVEGDDA----TPERVGLTHS--IGAAEPGDTVLLDDGRIECRV-ERVDGESVVATVVSGGKLSSRKGVNLPGVAIDVDLITAEDEAELDLAARANADFVAASFVRDAADVYQIADALEARGADIPIVAKIERAGAVENLDGIVDAADGVMVARGDLGVECPLEDVPVIQKRIIRKCVNAGVPVITATEMLDSMVSSRRPTRAEASDVANAVLDGTDAVMLSGETAIGDDPVNVVETMDRIVREVESSDEYAETREQRVPAAAEG-SRTEALARSARYLARDIGASTVVAVSESGFTARKTAMFRPGVPVVATTPNDRVRRQLALSWGVRPVLTE------YAHDMETILDNAVDAALDRGGAESGDTLVVLSGMLTGTNTTNTLKVHV. 469
250 0.000e+00UniRef50_UPI000D3E15CA pyruvate kinase n=1 Tax=Euzebya sp. DSW09 TaxID=2052804 RepID=UPI000D3E15CA  ali  34  15..................RRAKIVATLGPALDDREKLRAAIEAGIDVVRLNFSHGDHDTHARRLETVLELGARL-GRNVGSLADLQGPKMRLGLMPDDG-LEIETGSEVYLVEELESYESEGLKALPVVYDALAEDVEPGALLLIDDGSLRL-VASRVENGTVRARVVAGGRAKSRKGLNLPGVAVSAACLTDKDLEDLKFAMELGADWVALSFVRGPDDIIDVRNRIHALGGESPVIAKLERPEAIERLTDIIDVTDAVMVARGDLGVEIGPERVPAIQKEIIAEANAESRPVITATEMLDSMISSPRPTRAEASDVANAIFDGTDAVMLSGETAAGAFPVEAVRTMARIVEVAERS----PHLIHPSPPPHSELSVPKVVSQSAVQVARDVRATAIVVFSMTGWSVQLVSKCRPEMPLVGLTPSDRARRRTSMMWGTEAALVPMKDRAQ------ELLEAAERVLLDGNWAAHGDMIVLVTGPPGSLGGTSRIWVHRI 486
251 0.000e+00UniRef50_A0A2H0SBK2 Pyruvate kinase n=3 Tax=unclassified Bacteria TaxID=2323 RepID=A0A2H0SBK2_9BACT  ali  37  7............RNDTNMKRTKIICTIGPATETAATLLKLVKAGMNCARLNFSHGTYDHHSLLIKNVRSVSKKL-GQPIAIIQDLQGPRIRLGELPKDG-IAVKRGDKVALVYEKHAKLAAGMTVLPVQEP-LGTMVKEGEVILIKDGLVVMRAIEVH-GTMVVAKVEQGDVLTSNRGINLPESNLPDIVITSKDKKDVLFGLKEKVDWLALSFVRDAKDIKNLRKLLPKKGGQPRIIAKIERKEAVENFDEILEEADAIMIARGDLGIELPASEIPLLQKKFIEQARKASKPVIVATQMLESMTVNSRPTRAEVSDVANAVIDHADCLMLSGETSTGKYPVETCNMMADSITETEQS-----SYDDLPAQSVSRFTVPSVIAHTADDVVDHDHIKAIVVMSASGKSARLIASERPEVPILALTQNDVVRRQLALSWGISPYLMKRYNT------IDDLIDASVALVKRELKVKKGDHIIIASGHPTGPGALNLLKIHTI 484
252 0.000e+00UniRef50_A0A1G3XSK4 Pyruvate kinase n=1 Tax=Thaumarchaeota archaeon RBG_16_49_8 TaxID=1802371 RepID=A0A1G3XSK4_9ARCH  ali  34  6...................RAKTVCTIGPACSDRSVLRRLIQSGLNVARLNFSHGTLQEHTEVVQEIRRLTEMLK-MPVAVLQDLPGPKIRVGTIRGGSK-SLRKGEEVTLTVGKESKEE-ESEEIPVDFPQLPQAVTEGDSIYLADGAIRLRVLEKEENK-ILCRVVVGGTLLSKKGLNIPNLRIKLTPLSSKDRDALLQGLKLDVDFVGLSFVEEAEELLQAKSLIKEHGGRAAVIAKIERKQALNRLDAIVDAADGVMVARGDLGVEIGVAKVPAAQKRIIRASNSAGKPVITATQLLETMVQNPYPTRAEVADITTAILDGTDALMLSEETAVGRYPVEVLQVLLNVAQEAEKM----PTPEASMFNHASKRDVKEAMGWMASWAASQLKANVIVAPTRSGLTALQVSKRRPSIPIVALTPDIKILKQLLLARGVYPYLVDEIQS------IDDVFREVEDLVLKERWASEGDRIVIVAGDPAEPGTTNLLEVRV. 472
253 0.000e+00UniRef50_V2RJX2 Pyruvate kinase n=2 Tax=Mucispirillum TaxID=248038 RepID=V2RJX2_9BACT  ali  34  6...................KTKLICTIGPASNDPTVIRKMIENGMNVVRLNFSHGTHESHRATIKLVRSISQEM-GVHVGFLQDLCGPKIRLGILPEEG-VRLIAGDYIALASTNKKY----ENALPVEYDNLHKEVNIGERILLADGMLELCVTSIEEEK-VICKVITGGVVYTKKGVNMPQTDLHVPAFSEKDRIDLQMALEEKLDFVALSFVRSAKDLEEIKSIIDKSEHKPLLIAKIEKPQAVDNLEEILDVVNGVMVARGDLGVEMPLEEIPHVQKHIIKQARKAGRITITATQMLASMVKSQRPTRGETTDVANAVIDGTDALMLSDETANGDYPDTAVETLARIASAAEGYSRYTPDFDY--SLFRDNHAFTLAIGRAACWLAKDVGAKCIVCYSATGLAPYCISRFRPECELLVLTFDEKVCNMTSLIWGAQGVISELMT------DLESVIETAKIKSIEAGLAEHGDTIIVTAGMPFGKGTTSLLHLIQ. 471
254 0.000e+00UniRef50_A0A2E4VBV5 Pyruvate kinase n=2 Tax=Candidatus Poribacteria bacterium TaxID=2026781 RepID=A0A2E4VBV5_9BACT  ali  35  2................NIKKTKIVCTIGPASDSIKTITKMVGAGMDIARISFSHGTHQEKAEVIQNIKR-TEKDTGKRIPILQDLSGPKIRIGNF-NDEVVTLEEGNTFTLTT---QSISGNXKRVSFNTPEMISCIRVGEKIFLADGEIQLLV-EKVDDTXILCQVIAGGELRSRKGITIPGLQLNVGIPTEKDMIDLKFGVDLGIDWVAQSFIRDTSDVKSLRXQLKKLGHKKPIIAKLEKQEALSDLXGIIQSADGVMIARGDLGLEVPLQDIPNLQKEIIQVANSYGKPIITATQMLESMIYNPTPTRAEVTDIANSIHDGTSSVMLSAETAIGRYPVESVTMMTKVAKSTEDCLDYVTNFRSKPLVIKE--DLPDAVGNAACQIALEIGASLIICCTDSGKTVWNVSKRRPRALIAVASSNQETLRKCLLYWGTIDITTKDFQT------LEELVTVVKSSVIQLGLANKGDYIVIIAGDHVFSAQQNT...... 465
255 0.000e+00UniRef50_A0A1I5UH28 Pyruvate kinase n=57 Tax=Proteobacteria TaxID=1224 RepID=A0A1I5UH28_9PSED  ali  32  5..................KKVKILATLGPAIRDAAHIRQLVEAGVNLFRLNFSHGEHADHAQRYQWVREVEREL-NQPIGILMDLQGPKLRVGRFAEGK-VQLVNGQSLRLDLD---ASPGDASRVNLPHPEIIEALQPGMSLLLDDGRLRLKVTGKQADAVDTC-VIAGGELSDRKGVNVPEAVLQLSPLTEKDRRDLAFGLELGVDWVALSFVQRPEDIVEARELI---GGKAFLMAKIEKPSAVQHLEEIARLCDAIMVARGDLGVEVPAENVPRIQKDIVRTCRQLGRPVVVATQMLESMRFSPAPTRAEVTDVANAVAEGADAVMLSAETASGDYPLETVQMMSKIIRQVENGPDYQTQLDVGRPQAEPTAS--DAISCAIRRISSILPVAALINYSESGASSLRASRERPKAPILSLTPSLTTARRLTVAWGIYSVVNERLRR------VEEVTSTALEIAQAQGMAKRGETVVITAGEPFGPGSTNSLRIET. 469
256 0.000e+00UniRef50_Q11V95 Pyruvate kinase n=41 Tax=Bacteria TaxID=2 RepID=Q11V95_CYTH3  ali  37  4..................KKTKIIXXXXXXXXXXXXXXXLVQAGANIFRLNFSHGTHDVHQGVINAIRELRKEH-NVNIAILQDLQGPKIRTDEVENNG-VELVAGAQIVITKEKML---GTKDKISTSYKMLTSDVKKGDAILIDDGNIELKVLETGNG-EVTCVVIYGGILKSRKGINLPNTIVSEPSLTDKDKEDLLFGLKNEVDWIALSFVRSAVDLNELKAIIAEHGKSCKVIAKVEKPEAVKDIDAIIEASDAIMVARGDLGVELQMEDVPMIQKMIIKKCNQLAKPVIVATQMMESMITNARPTRAEASDVANAIIDGTDTIMLSAETASGNYPVITVKAMTRICQAVEKEADIYN-----KSTLDDITNTSDSVIASACELADKVNAKAIIGLSQSGYSAFRIASHRPKASIYIATHDEQLMNQMNLVWGVQAFRFEKFTT------TDESIEAVKKSLVEKGLLKKGDIYVTTASMPMDIQLANSLKLGIV 469
257 0.000e+00UniRef50_A0A2E9R1X7 Pyruvate kinase n=2 Tax=Bacteria TaxID=2 RepID=A0A2E9R1X7_9DELT  ali  32  36..................KRTKIIATLGPATFASERIQQLIEAGVNLFRLNMSHGDYDGYIQAHTYIREASDRL-NTSVGIIADLCGPKIRTGQFKDG-PITLTPGQQVTITTRDVEGEDG---LIPSQYEQIADDLSPGDRVLLADGTMELTVESI-DGTEVECVVVHGGELGSRKGINLPGVEISAPSMTEKDFEDAVFALDLGVEYLALSFVRKPQDLDELRDLIKKKRKRTGIIAKIEKPEAVERIEGIVDKADVLMVARGDLGVELPVEQVPLIQDELVNYARSRNRPVIVATQMLETMIENPTPTRAEVADISHAVRSGVDAIMLSGETAIGKHPIKAVQLMSRVAKQAEGHIWNKAYFGSLATQAPASITLSDAIANATAMLSRDLQVRAILVPSTTGTTARVLSASRPAAPLVAFSSNIHTCRKLSLMWGVTPIYFEEA-------DLYQLDKLARHLTKRLEFANEGQSILLVKGFNPDP........... 497
258 0.000e+00UniRef50_A0A120FZC2 Pyruvate kinase n=93 Tax=Pseudomonadales TaxID=72274 RepID=A0A120FZC2_PSEFL  ali  34  3.................VRRTKIVATLGPASNSPEVLEQLILAGLDVARLNFSHGTPDEHKARAKLVRDLAAKH-GRFVALLGDLQGPKIRIAKFTN-KRIELKIGDKFTFSTS-HPLTEGTQDVVGIDYPDLVKDCGVGDELLLDDGRVVMRV-DTATPTELNCTVIIGGPLSDHKGINRRGGGLTAPALTEKDKADIKLAAEMEVDYLAVSFPRDAADMEYARKLRDEAGGTAWLVAKIERAEAVETLDGLIKASDAVMVARGDLGVEIGDAELIGIQKKIILHARRHNKAVIVATQMMESMIQNPMPTRAEVSDVANAVLDYTDAVMLSAESAAGPYPLEAVQAMARICVGAEKHPTSKT---SSHRIGKVFESCDQSIALAAMYTANHFGVKAIIALTESGYTPLIMSRIRSSVPIYAFTPHREAQARAAMFRGVYTIPFDPASLAPN-----EVSQKAIDELVKRGVVEKGDWVILTKGDSYHTGGTNGMKILHV 478
259 0.000e+00UniRef50_A0A1V6JE20 Pyruvate kinase n=1 Tax=Bacteroidetes bacterium ADurb.Bin012 TaxID=1852796 RepID=A0A1V6JE20_9BACT  ali  35  2...................RTKIVATLGPASFDKSVIERMTKAGVNVFRLNFSHGDHNILRQIIHYIRELGPAYHHR-LAILGDLQGPKIRIGEVENNA-INLRQGQEIQLGGGSGLSK---EDILWINYPALTEDVKPGDQVLLDDGKLSLIVKEKLPSGFLRAEVLVGGILTARKGVNLPDSHLTLSALSEKDLTDLRFAYQNQLDWIALSFVRSSEDILKLRENIQGRNWNPGIIAKIEKPEALKNFDSIIEVSDALMVARGDLGVELPYEQVPAVQKLVIHKSIAQSKPVIVATQMLEGMINNTRPTRAEINDVANSVMDGADALMLSAETSMGQYPVEAVEAMRRIIDETEKIGEIHNRKPENSFTNPSRL-ISDAVIEAAIHLSEKTEAKAILTYTLTGYTALRLASYRPKAQIFIFARSPRLIRRLSLVWGITGFV------QQNLHYTDDNLDLMVQILLQNNAVNPDDILVKITGFPMKERATNMVVVTRV 473
260 0.000e+00UniRef50_A6DH47 Pyruvate kinase n=1 Tax=Lentisphaera araneosa HTCC2155 TaxID=313628 RepID=A6DH47_9BACT  ali  34  6...................RTKIVSTLGPTT--KGRLKELIEEGVDVFRLNFSHGSHEEHAERIQEVISAATELK-RTVGILGDLQGPKIRCGKIIEGG-IQLEAGQELVITTDEIL---GEGSRISTVFQALPREVKVGDPILMDDGLLEAVV-ERIEGNEIFCKMLVAGKLTSNKGINLPETDIQSPALTEKDERDLKFIIENDIDFVALSFVRKGEDLDIIHAAMDKIGKRKPVISKIEKPSALVDIDAIIEKSDALMVARGDLGVEIPSEKVPVAQKTMIRKCIEQGKPCIVATQMLDSMIRNPRPTRAEASDVANAVLDGASAVMLSGETASGSYPVEAVQMMTKIIRETERNFMTKPGMWGYEQ--PEIRNDVDALCKSIVDLSETLNVKGIICITNTGKTALRIARFRPACPIFAFASHENVLRKLSLPKAVVPMPLKDLTYD------ESTLTQMEEALDRHPFLDNGDQVILAAALPFDKTSTNLIKLHTI 473
261 0.000e+00UniRef50_A0A2D7TFP6 Pyruvate kinase n=4 Tax=Cytophagales TaxID=768507 RepID=A0A2D7TFP6_9BACT  ali  36  2.............SKTKINRTKIIATIGPSSSDYNILKDMISRGVDVVRLNFSHGSHEDHLQTIKNVRKISDEIK-VPITILQDLQGPKIRVGKLKKDKFFXDDX-SXLMITSEXIEGDXDXISID----NDVINDIRVGERILIDDGKLELKVTE-NSKKXIXAKVLRGGYILPRKGVNLPESDIKLSSITQKDIEDLKFGLKNGVDWVALSFVRSDKDILELKSLINKEGYETKIIAKIEKPQAIKHINEIIDYSDGLMVARGDLGVEMPMETVPVHQKKIVKKCNLACKPVIIATQMLESMINSKTPTRAESNDVANAVLDGADAVMLSAESATGSFPLLAVESMERIISSVERT--SSEIYFKFEKRKKLKDRLSEXLINVACRLSDQISAKALVTMTKSGYSAYRVSGSRPKAKIYIVTNNKKIGNELNLLWGVRXIYYDK------XENIDSTFEXIEKILVXGGHLSKNDKXIITSSMPTWKGHTNMMKINVV 474
262 0.000e+00UniRef50_D3FCL3 Pyruvate kinase n=8 Tax=Solirubrobacterales TaxID=588673 RepID=D3FCL3_CONWI  ali  36  2...............IPVRRTKIVATIGPASRDPEVLVRMVEAGLDVARLNFSHGSRDEHEENVQLVRQAASR-AGRQVAILQDLPGPKLRIGSLKND-HVDLRVGDKLTLRCGSE--GEGDVDAICVSWAGLPDAVEDGDVVYLADGRIRLAVKGVRTDTEVDTVIETGGPVASRQGLNIPGSTRGLPAVPKRDLELLEFGESIGVDLVALSFVREPSDVVEVRKH-----TRLPLIAKIEKPQAVENAVEIIRAADCLMVARGDLGIELPIEDVPVVQKQLLRIAGRLARPAITATQMLDSMITSSRPTRAEVTDVANAIFDGTDAVMLSQETAVGAHPVLVVRTMATIAERTERELPYEQWNDSRVR--RDARDPAYTVAHSACEAARELGLAALVIPTLSGRSARLISAHRPNVPIYALSPGKETVRRCGLMWGVEA------ASMRRHEITEELIRDAGRRAVELGWVKPGDRIGITAGLPSGPGTTSLFQVETV 471
263 0.000e+00UniRef50_A0A2E5XD20 Pyruvate kinase n=6 Tax=unclassified Flavobacteriales (miscellaneous) TaxID=403978 RepID=A0A2E5XD20_9FLAO  ali  32  2...........IEKKYRFKRTKIIATIGPSSHSKKIIREMIMNGLNVCRINFSHSNHSDALGIISIVRELNNEL-GSHVAILGDLQGPKLRVGEVENGTF--LNKNKLVNISYG---LQASNKKNIYVNYITVREDVKKGDKILIDDGKIILKSIE-LNGPKIICKIIQGGELKSNKGVNFPNTKINLPPITDKDNADLLFCIKNNFEWIALSFVRSSKDIITLKKLIVEKKSNCKIIAKIEKPDAIRNINKIISNSDALMVARGDLGVEVPPQKVPVLQKKLVRAARKSAKPVIIATQLMESMTQNMIPTRAETNDAANAVFDGADALMLSGETSIGKYPVRVVKTVSKIIIDVEAS-DERKHFNKFLPLRKDKRYISDSICYQASEIANQVEAKAILAFTASGYNAQKISSNRPNAYICVFTYNKQLLNTLSLVWGVIGFYYNKF------ESTDNTIEETQSMLKSVGILKKNDFVVNIASMPIKKGMTNMLKLEKI 477
264 0.000e+00UniRef50_A0A2E4SB67 Pyruvate kinase n=3 Tax=Flavobacteriales TaxID=200644 RepID=A0A2E4SB67_9FLAO  ali  33  3..................KRTKIVATVGPSTHSEDIIKNMILEGVNVFRINFSHGSHEDHIKAINKIRKVDKTL-GTHSALLADLQGPKIRIGEMPEEG-VLLEKNSAFTLYTNDKKSI---ENAAFVSYDRLAKDVKKDEFILLDDGKIXLKVTETNGKDXIKTKVIAGGVLYSRKGVNLPNTKISTSSXTEKDKXDLKVALEQGVDWVGFSFVRSAREIIELRHLITSMNGDAKIIAKIEKPEAVEDLDNIMQETDAVMVARGDLGVEIPLENVPLIQKRIAEMAKEMAKPVIIATQMMESMMDXITPNRAEVNDVANAVMDGVDAVMLSGETSVGKHPVEVIKIMARIINEIEG-KYXELYVKETMPKKNNERFITDSICFNACRLAQRVNAKAXITMTXSGYTSYKISSQXPESAIYVFSSXKKLLSTLSLVWGVATFYYDKTIS------TDHTIADIHHLLKSEKLVESGDLIINTASIPLGEGGTXMLKLSYI 473
265 0.000e+00UniRef50_A0A0C2VY08 Pyruvate kinase n=473 Tax=Bacteria TaxID=2 RepID=A0A0C2VY08_9LACO  ali  39  1.................MKKTKIVSTLGPASTDVDTIVKLIESGANVFRFNFSHGDHEEHFDRLNKVHEA-EKRTGKTVGLMLDTKGAEIRT-TIQKDGKIEFHTNDEFRISMDESI--EGTKEKIAVTYPGLLADVHVGGHILFDDGILDSVIKEIDENKELVVVAQNNATLGSRKTVTAPGVSINLPGITEKDSSDIRFGLEMHINFIAASFVRKPEDVLDIRKLLDEHKEDVQIFPKIESQEGIDNFEEIMKVSDGLMIARGDMAVEIPAENVPIVQKHLIHRCNEMGKPVITATQMLDSMIENPRPTRAEASDVEYAVLSGTDATMLSGESANGDYPAEAVATMAKLDVKAENHYDEYGDARPAFNNG----DVTEAFGKQVAEMVKDLDIKTIVTTTSTGYSARMISKYHPNADILALTFDDRVRRGLMVNWGVQPIVVDK------PENSDGMFDFAAKKAVETGLAKEGDLILVVAGLPVGKGTTNVMSV... 470
266 0.000e+00UniRef50_A0A2A4X9K5 Pyruvate kinase n=1 Tax=Candidatus Aerophobetes bacterium TaxID=2030807 RepID=A0A2A4X9K5_9BACT  ali  36  4...................KTKVVVTLGPATNSYEMVEQLVCLGMDVARINMSHGEYEEHRQTIAWLKKARKKL-GKPLAIMLDTKGPELRVGKISGG-SIELKEGDEVEL---GEKSSSSKSVFIPLDPAHIIKEIPVKATVLFDDGYIETCVVETLE-KSVKLKVLKGGSLKSQKGINIPGVSLSLPALTERDKEDIASGISEDIDIVAASFIRSAKHVESILDWMRQKGGDTLLLAKIESAEGVANFDAILEKVDGIMVARGDLGVELPLTQVPQLQKMMIRKCYKAFKPVITATQMLETMIDNTRPTRAEVSDVANAIYDLTSAVMLSGETAIGKHPLQTIKMMQEIIFEAEQNLKLEEFFQKEAEKSP-FSDSSHAIAIAAVKTSYILKSSVIVAVTSSGYCPNLIARFRPAMPILAITMREKVFNQMAFFWGVLPHLC-------SVKDICSATTEAKKIIKEAKLAHSGSVFVITTGTPFGKGSTNSI..... 467
267 0.000e+00UniRef50_A0A0S7BTS2 Pyruvate kinase n=1 Tax=Lentimicrobium saccharophilum TaxID=1678841 RepID=A0A0S7BTS2_9BACT  ali  34  1.................MRKTKIVATLGPASIAEPVLRSLMLAGVNVFRLNFSHGSHEVHAASLETIEKLNAEL-GLHVAVLADLSGPKIRTGEVEYDA-MELMVGDEVTITCKGELCRNG---LISVNYTDFARDVRAGEDILLDDGKLLLRAVESDGENTVRAKVVQGGILSSRKGVNLPRTNLSLPSLSEKDLSDLDFVMKHNIHWVALSFVRSAADIEELRRRIAPEARSLRIVAKIEKPEAVENAEAIIRASDAVMIARGDLGVEIPQEQVPIVQKKFVRMCIAASKPIIIATQMMEGMINSMRPTRAEVSDVANSVLDGADALMLSGETSVGKYPVQTVETMNRIISDVESGGMYFPEIKY--EEAPPERRISDAVIMAAADLAGKVNARALIAMTHTGYSAFRLASHRKGAGIYIFSNNRRLLCALSLVWGIEGLYIEKYTS------TDAAMLDMRKALIARGCITQGNYIIYVSSIPIGPGKTNMLKLSIV 473
268 0.000e+00UniRef50_A0A2V8RPU4 Pyruvate kinase n=2 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V8RPU4_9BACT  ali  34  210.................VRRAKILATLGPASRELAVLESVLAAGANAVRINMSHGTQEEHAETIRRARSAAERLK-RPLSVLVDLSGPKIRTGMLKGGQPVLLDANALFTLTTRSVV---GDSREVSTNYAGLARDVRPGARVLLDDGAIELLVERTTE-TDVVTRVVNGGTLAERKGINLPGVTLPIPSLTDKDRRDLHWAVREGADYIALSFVRRAEDCAEAKSLIKAAGGRQPLVAKIEKAEAIENLEEIIAASDGAMVARGDLGVETSVELVPVYQKRIIETANRREKVVITATQMLQSMISEPRPTRAEASDVANAVWDGTDAVMLSAETAAGKYPVLAVATMARIIESAEDGKPT-YSRDLTRLAGRQSGRVSRALSEAAAFAAEEVGARTIAVITASGLMAHRLSNLRPAQRIVALTEDPRVRDELSLVWGVETFVHPRC------DNTEDMLKICERALVEAGIVQQAETFVLMAGRLSGLGLSSSVTIYTV 680
269 0.000e+00UniRef50_B7G6Z9 Pyruvate kinase n=5 Tax=Bacillariophyta TaxID=2836 RepID=B7G6Z9_PHATC  ali  32  76................RWRKTKQVVTLGPASSNKEMIEKLFLAGADVFRLNFSHGSQEQKKELLIMIREVEEKYS-HPIGILGDLQGPKLRVGEFSKPEGEFLELGQSFRLDLDNA---KGDNKRVQLPHPEIIKASELGHALLVDDGKVKLVVTAKGDD-YLECRVDVAGMIKDRKGVNTPDSVLEISPLTPKDRSDLEYMLGIGVDWVALSFVQTPADMVEIHALIDEKQFKPAVMAKIEKPSCFDNLQRIVGLCNGIMVARGDLGVECPPEDVPLLQKEIIDECRNQGRPVIVATQMLESMIEVPTPTRAEASDVATAIYDGADAIMLSAESAAGKFPEESVAMQQRIINRVEGDKHYRSYLK--QNEPDPENTPTDAIITAARQVAKTIGAKSIVCFSLRGSTVLRASKSRPGVPILALCPFKETSRQLALSWGVYSFNYDRPMVEKSTDDFDLVLKNACRAALKKGLVSPDDLLVVTAGLPFGPGAANIIRVV.. 576
270 0.000e+00UniRef50_A0A1R0IQH5 Pyruvate kinase n=8 Tax=Sulfobacillus TaxID=28033 RepID=A0A1R0IQH5_SULTH  ali  37  1.................MRRTKIVATIGPACDDPQVIANMIRSGMDVARLNLSHGDLKTHRQRIQLLRSISHQL-GTEVGIMLDTCGPEVRLTHLTQ--PLTLNQGDIFILTKTPEPG----SYQAGVTWDGIFDMIEPGHLLWIDDGNIVMRCTDQQPD-ALRLEVVVGGLLQNRKKISSPDLTWPLDILTDTDREALLMGMQEGMDFVAASFIRSAEDVVTIRKFFEENHFDVFLISKIENRAGVENLAEILAVSNGVMVARGDLGVELPPERVPWLQKDIIAQANELGIPVVTATQMLESMTHAPRPTRAEVSDVAHAIWDGSDSVMLSAETASGLYPVESIQMMAKIAEDA------DNRREFMTRRSLPITRVADAVSRASAEVAESLEARAILTVTATGYTARMVSRSRPSVPIIAISPNPGVVRRLKLTWGVCPI------SSEDAEHSDDMVAKAIEAAADYGYVAEGDLVVLTAGVPAGPGTTNLVRVETV 464
271 0.000e+00UniRef50_A0A0G1DXR5 Pyruvate kinase n=11 Tax=root TaxID=1 RepID=A0A0G1DXR5_9BACT  ali  37  4...................RTKIVATLGPASDNLYTLERMLQAGMDLARLNFSHGSYENFSQIIKNLRLAATK-TGKNIAILQDLQGPKIRVGKLPNEG-FKIEKGQKIILSVSPKKNE------IPIQYKKLPKEVKKGDIILIDDGLIELQVLSTT-DKTITTRALNKGIITSNKGINIPGCKLNADSLTKKDLNDLRFGIKEGVDYVALSFVKSKEDILNLRKKIEKLNSNPKIIAKIERKEAIENLREIIEVSDGIMVARGDLGLEVPAEMVPIYQKEIIHLCNEQAKPVIVATHVLQSMIESPRPTRAEISDAANAIFDRADAFMLSNETAVGKYPLKAVRTLADVGRAVENELK-KRPFLLTPLHENKHLSITDASCLNAINLAENIKANHLVLLTEKGYTARQIAKYRPMTELIAITTSEKTKRELALIWGINKILI----SDSSIKNESGLETATIKLLKKNRLIKPGDKIVIIS................. 454
272 0.000e+00UniRef50_A0A2H0PC75 Pyruvate kinase n=2 Tax=unclassified Elusimicrobia TaxID=1797919 RepID=A0A2H0PC75_9BACT  ali  34  14..................KLTKILATLGPVSAKPAMMLDLLAAGVDAFRLNCSHASLDELAKNVDLI-RSLSRRSRRACSVVMDLQGPRLRVGRLRNGEPIDLKRGARTRIS---VHDIPGTAEEFSTSFRKLPQTVKKGMEIRLDDGSIVLTVLKTGAG-WVDCEVLIGGKLKEHKGINLPGADIDLPALTAKDLKDLEMGLKCGIDHVALSFVRSPDDILKARRLIQKAGAPTRIIAKIEHPLALDRIDDILDASDGIMIARGDLAVELSAAEVPALQKMLVRRANDAGKLSIVATQMLESMISHAQPTRAEASDVANAIYDGADVVMLSGESAVGLYPVETVTVMADIIRRAESSNFRYRMIPHGLLDSPE-TGFAHALARATHDACDITGAKAVIVYTMTGWSARIMSKYRPYAPIIALTPLKATYNQLALYWGIAPMICP------LGKTTDEMLGYGERILLQSGVVRQGETTLVTAGGTAKHKASNMLKIHVV 483
273 0.000e+00UniRef50_Q83AU7 Pyruvate kinase n=1097 Tax=Bacteria TaxID=2 RepID=Q83AU7_COXBU  ali  36  4............NNNHMLRSTKIIATLGPATDDLSILEEIIHEGVDIIRLNFSHGTHEKHKQRIEMVRKAAKKQE-RVIGILADLQGPKIRISSFKTGK-INLKKGELFILDAG-LPPEEGTEKSVGIDYKNLPKDVKAEDILLLDDGRLTLKVQNV-KGEQIICRVVEGGALSDHKGINRLGGGLSAEAMTEKDINDLKFAVDFDVDYVAISFPRDAQDILKAKHLVQGYKGKAGIIAKIERTEAVKNIDAIIEASDGVMVARGDLAVEIGDAQVPLVQKDIIHRARSMDKPVIIATQMMESMIHATVPTRAEVSDVANAVLDNTDAVMLSAETAVGDYPVLAVAAMARTCVVSES---QPRSHISRHRVECRFKRIDEAIAMATMYAANHLDIKAIITLTESGITPLWMSRIRTAIPIYGLSRFDKSLGRMTLYRGVYPIKFDPTQYTR-----DEINVKAVETLQSQDLLKNGDLVVLTKGDYMGVGGSNAMKIMVV 480
274 0.000e+00UniRef50_A0A2H9PN59 Pyruvate kinase n=1 Tax=Candidatus Woesearchaeota archaeon CG_4_10_14_0_2_um_filter_33_13 TaxID=1974449 RepID=A0A2H9PN59_9ARCH :_  ali  39  1.................MRKTKIICTIGPATMSEEAITRLIKSGMNLARINFSHADHEEHLIKIKNIRNVSKD-----IPLILDTSGPEIRTGKVKNGR-INLEEGKEIIITTKEVL---GNTKVVSLNLKKITDIVKPADLILIEDGRIELIVKRVQQ-KEVVCQIVVGGELGNNKNVNIPNRDIDLPAITEKDIKDIIFGIAHNFDFIAASFIRSKEDITAIREILQQHKKDIKIISKIEHKKAIDNIDEIIAASDGIMIARGDLAVQIETHEVPIIQKLIITKCLQAKIPCIVATEMLQSMVNNPRPTRAEITDVANAAFDGADAVMLSKETTLGKFPFRTVETMSNILENAEKTISTKD------KNYLKSNCKVEAIAKFAVEAAEELNAKCIIVPTVSGSTVRKISSLRPNMNIIALSPEQKTVRQLELSYSVIPKIMK------HPNDVDQLIKESIWLAHKDGLVNEEDTVVITAGVPIGVNTTNLLEIRVV 463
275 0.000e+00UniRef50_Q9VD23 Pyruvate kinase n=15 Tax=melanogaster group TaxID=32346 RepID=Q9VD23_DROME  ali  43  1............................................MRVVRMNFSHGSHEYHCQTIQAARKAIAMYVERTLAIALDTKGPEIRTGKLAGGAEIELKTGDKVTLSTKKEMADKSNKDNIYVDYQRLPQLVKPGNRVFVDDGLIALIVKE-SKGDEVICQVENGGKLGSHKGINLPGVPVDLPSVTEKDKQDLKFGAEQKVDMIFASFIRDANALKEIRQVLGPAGACIKIISKIENHQGLVNIDDIIRESDGIMVARGDMGIEIPTEDVPLAQKSIVAKCNKVGKPVICATQMMESMTNKPRPTRAEASDVANAIFDGCDAVMLSGETAKGKYPVECVQCMARICAKVEAVLWYESLQNSLKREIRTSADHISAVTTAIAEAATVGQARAIVVASPCSMVAQMVSHMRPPCPIVMLTGNESEAAQSLLFRGIYPLLVEEMVIGSF--NFRRIMQSGLKLMGKMDILEPGQKVVLV.................. 446
276 0.000e+00UniRef50_A0A136MLA3 Pyruvate kinase n=4 Tax=Bacteria TaxID=2 RepID=A0A136MLA3_9BACT  ali  35  1...........MPTSNLHVKAKILCTMGPAVASVQKINAMIKAGANAFRLNMSHGSYSMHKEFIGYIRTAEDKL-NRHIPIVLDLQGPKIRVGDLGGRPFITLLAGHEVMLTIMKNKKHVASDNLIPVQYPTLAKDVKPGDELLLDDGLLKLKVLSTKGDT-VRCMVVYGGDLKPRKGINLPQTSVSQPSMTSKDRADIRFGIDHDVDYIALSFVRTASDIEAVRKYITKYGGTQQVVAKIEKPEAVQNIESIVRASDVIMVARGDLGVEIPAESVPMVQKHIISICNAYAVPVITATQMLESMIQNPRPTRAEASDVANAVLDGTDAVMLSAETSVGAYPVEAVHYMRLICSKAEQALSHSRHPYAA-EGGATTLSNTQSIAEAAAQISEESRVAAIVSLSYSGETARLISSRRPKAPVIAITTLRSVARRMNLVWGVSSLILE------TVSTTDDTIESIKQHLLQEKYVANGSTVVFTIGRPVGRARTNMLSLETI 484
277 0.000e+00UniRef50_A0A2A1ZQ56 Pyruvate kinase n=2 Tax=Tenericutes TaxID=544448 RepID=A0A2A1ZQ56_9BACT  ali  39  3...............IPFNQTKIICTIGPATESKEMMTSLINAGMDVMRMNFSHGNHESHLERLKTLYEINTDL-NTNVASLLDTKGPEVRTHLFKNSK-VSIEKDSIVTIYMTEIL---GDETKFSVSYENLYLDVLVGGSILVDDGYLELKVMDIDDKKTIKTKALNTHIIKDRRGINIPGAKLNMPFISEKDHADLKWGCLNRVDYVAASFVRRASDIKEIKDIFAKCGNHTQIIAKIENAEGVLNIDEIIEIADGVMIARGDLGVEVPAEDVPIIQKSIIGKCHIKGKISVTATQMLESMIDNPRPTRAEVSDVANAIYDGTDAIMLSGESAIGIYPIESVEVMNNIAQRIERELDRARLVKRANKNSHDGIET--SIAVSVAYSVIQGDTDIIVAPTVSGNTAKLISKFRPDARIIALTPNAEKARSLALYNGVEARVF------NLEPDTEYLIKEAIKLVKSEYNCKPGTRVVVTGGFPIGTQ-TNSFRIIDI 475
278 0.000e+00UniRef50_A0A0G1TIW9 Pyruvate kinase n=2 Tax=unclassified Parcubacteria group TaxID=1794840 RepID=A0A0G1TIW9_9BACT  ali  36  8...................KTKIIATIGPSCASEAILQALIERGLDGARLNFSHGTHEEHMHYARTIRRLAKQM-GVPVALIQDLSGPKIRLGEIAGGV-VMVKRGDPYTFTTRQGI---GNADVASVNFPLLPRFVKRGDALLLDDGTKRFRVAGKT-DTDVHTVVEIGGEIRSHKGINLPHVKAK-DVFTQKDWDDLAFGLEIGVDYVALSFVRDEKDIQQVRQFLAAHKSSAHIIAKIEKQEAVDNLDSILDVSDAIMVARGDLGIEVSIEDVPIIQKRAIHLANTKAKPVITATQMLESMTTSPTPTRAEATDVANAILDGTDATMLSGETANGDDPVRVVKTMETIARRTLDMFPYDYWMEH---SEPDMSDTTAALSYASVILANRIDTKIIVALTESGHMARLISRHKPSQLIVALTPNQTTLQQLAISWGVLPIH------TRAIKDLKDSLNVARTIIRQEGLLNDGDPYVVIAGRQLGD-STNVLLVQKV 473
279 0.000e+00UniRef50_A0A2I0M6R7 Pyruvate kinase n=8 Tax=Bilateria TaxID=33213 RepID=A0A2I0M6R7_COLLI  ali  54  24.TFLEHMCRLDIDSEPTIRNTGIICTIGPASRSVDKLKEMIKSGMNVARLNFSHGTHEYHEGTIKNVREATESFTYRPVAIALDTKGPEIRTGLIKGSAEVELKKGAQLKVTLDDAFMENCDENVLWVDYKNLIKVIDVGSKIYVDDGLISLLVKEKGKD-YVMTEIENGGMLGSKKGVNLPGAAVDLPAVSEKDIQDLKFGVEQNVDMVFASFIRKAADVHAVRKVLGEKGKNIKIISKIENHEGVRRFDEIMEASDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNRAGKPIICATQMLESMIKKPRPTRAEGSDVANAVLDGADCIMLSGETAKGDYPLEAVRMQHAV..................................................................................................................................................... 380
280 0.000e+00UniRef50_UPI000A1D0DEE pyruvate kinase n=2 Tax=montium subgroup TaxID=32352 RepID=UPI000A1D0DEE  ali  37  14.TELNHICELEIKTASHQRLVSLIATISTSSRNTDTIYKMIMKGVNIFRLNFAHESHEMHSKTIELINEALEKIHKRTVAIAADTRGPQIRTGLLDGD--VFLRTGDNLRLSINRDLYDKGNKEAVYVDYPNIINLTKTGDRLFIDDGKLLLHVMEVGVDG-LLCEVIQGGQLKNNCNVILPEIEIDLPAVSEKDMFDIQFSMKANVDFLFASAVRCAKNIKELRAVLGEKGRHIKIIAKIDSKISLSRFSEIMRAADGLLLSRADLGTQIPIHKLFITQKSILGQCNKAGKPVIVASHILESMRTEVQPTRAECFDLANAIIDGADCIMLSSEVAIGPYPTEVVATCDKLCREAEKVLWFRDLFSDLVSEVRGELDAAHSLAIATVETAKRTNATLILVLTSSGRSATLVSKFRPRCPIMAITRCERAARWVYIHRGVLPMLYTSEPSSDYATDVDARVHFGLTCAKKMEIISDGDPIVILSAWKDGGGFTNNLRVV.. 513
281 0.000e+00UniRef50_A0A2H0ML51 Pyruvate kinase n=3 Tax=Nitrospinae TaxID=1293497 RepID=A0A2H0ML51_9BACT  ali  35  4..................RLTKIIATLGPASGNKNQIRGLARAGVNVFRLNLSHGDHSVVRRWIKFIREVEAE-TGIFLGILLDLQGPKIRVGKFEGG-SILLHKGQKVVLSTDRGMGRDG---WIPVQYAHFPKEVKPGDPVFLDDGKLCVRANRVIANR-VEAQVEVGGRLSNFKGLNLPDALIQTSPLTRKDRADLKFGLHEGVDFVALSFVGMARDVLQLRRLIRSQGGDAEVVAKIERKQAVQNLDEIVEASDAVMVARGDLGIEMPLSDVPVVQLKILQACAKHAKPVIVATQMLETMIENSRPTRAEISDISNSVSDCADAIMLSGETAVGKHPRAAVSVMVETALKTEEFQRENQRILPWSWFFKDQPPVHLGITYSANRLVELLGAKAIMLFTLTGGTARMVSSPHPMVPLLAFTSCRKRARKLTLVRGAVPFMVEE--SKNFLENLGELFR----LLKKNRLVKKGDRVVITTGLPMGPQWTNVIRVERV 474
282 0.000e+00UniRef50_Q44473 Pyruvate kinase n=1655 Tax=root TaxID=1 RepID=KPYK2_AGRVI  ali  34  7..................RRSKIVATVGPASSSPDMLRSLFLAGVDTFRLNFSHGARADHAEVYRNIRALEQEH-DAAIAVLQDLQGPKIRIGVLAHGR-LDLARGSTIGFILGREGGEGMND--IPLPHREIFEVAVPGMDLLIDDGRIKVRIMEVMDGRLV-CEVLNGGALSNRKGVNVPGAVLDISPLTAKDREDLEFGLELGVDWVALSFVQRARDMIEARSLVGDRAG---LIAKIEKPSALDDIEDIVRLSDSVMVARGDLGVEIPPEDVPGKQKEIIRACRLAAKPVIVATQMLDSMVSSPTPTRAEASDVAGAIYDGADAVMLSAETATGAYPVEAVEIMNRIIEKTEKHKHYRPILEATEPDVAQ--SPPHAVATAAANVAVALGSPVVVAYTSSGTTAARISRARPALPILALTPSEQVARRLNMFWGVVGV------RSQDVHTYEASLIHAQQAVQEAKLASPSDHIVIVAGFPFAQGSTNNLRVVQI 473
283 0.000e+00UniRef50_A0A2E1X205 Pyruvate kinase n=2 Tax=Planctomycetes TaxID=203682 RepID=A0A2E1X205_9BACT  ali  34  7...............PAFRQTKIVATLGPASISTEVIRGMLQAGLDVVRINASHGEHDKDAETIQKVRSISQEV-GHPVGILYDLQGPKIRLADFSGD-PIKVEAGDEIRI----AVNRPAEAGEIGSDYDRLDQDLAVGDPILIDDGIIALETISVSDG-LIIGRAENSGVILPRKGINLPGSDISAPAFTNKDREDALFAVSQNVDFLALSFVRRARDVQQLQEMLADNGSTIPVISKIEKSRAVADVTQILQNSWGAMVARGDLGVEVPPQQVPVIQKNIIAEGLRLGRPIITATQMLDSMTRNPRPTRAEASDVANAVLDGTDAVMLSAETAIGDYPVESVKMMSDVITYTEQHSSIDYYRGKRERSV---DSTPEAVTDAACQVAHNVEAHALVAFTQSGATALLASRRRPERPILAFTTQPDVRNRLTMVWGVRPYQIRPASM------TDQLIEELDSTLQTDGLASRGDLLVLLLGAPTHRGRTNLMLVYQV 476
284 0.000e+00UniRef50_A0A2H9PEH7 Pyruvate kinase n=5 Tax=Bacteria TaxID=2 RepID=A0A2H9PEH7_9BACT  ali  35  1.................MCKTKIICTIGPASEKPTTIEKMIKSGMDIARLNFSHGTHEQHGEHIVIIRKASNKLS-KYIGIMQDLQGPKIRIGKFKPGKNIVLQPGEKFILTTENC---SGDRNRVNVDYKKLHGYLAKDDRIFLDDGKIELLVKKVN-NRNIESEVIIGGELSERKGVSLPDKPLPSPLVTQYDINDLNFGMKLGVNYVAVSFTRKKENILKIRNLLR-NNNEISLIAKIEDAEGLNNIDSIIDVSDGIMIARGDLGVCIPRAEVPLIQKEIIRKCRKSGKPVIVATQMLDSMTTNPHPTRAEVNDVANGVLDGADCLMLSAETSVGKYPVEAVQEISSIINTVENSTDYRRTLTS-EEFYPQERGLIQGLGIAIDKLSQVDNVKVIICLTKTGNTAKIISQYRPQLPIIAVTVNKTIAMKLLVYWGIKVLIGKK------VKDVEQNYKTFVKHVRREGLVNEGDIAIITSGIKEKPFQAN-ISVVEV 470
285 0.000e+00UniRef50_A0A097IU92 Pyruvate kinase n=18 Tax=Stramenopiles TaxID=33634 RepID=A0A097IU92_SACJA  ali  41  60...................LTKIVATIGPVSEDFEPLQQVVDAGMRVMRINFSHATFEEAEKRLTNLRACKGKHAKACLAVLLDTQGPEIRTGNVEGGGKIELVQGSTMELTTNPDHREVGTAEKLFVSYRGLTGAVTAGSAILLDDGQVSLRVTDVRE-ESVTCLVENSGTLKSRRGVNLPGAHVDLPALSEKDKIDISYGIQNDVDFVAASFVRKAEDVRSIRRFIEDIHSKARIISKIENLEAVDNFDEILELSDGIMVARGDLGVEIPAQQVTNLQKKMVRACNRVGKPVIVATQMLESMQTNPRPTRAEVSDVTNAVYDGADAVMLSGESAQGKYPVESVEMMRCIIDEAESWKVSNPELVLPDEPEASMTSEMEGIASAAVHAAHSLKAKLIVVVTKKGHLARLVAKFRPNVPVMASCPDRKVGRQLILHRGLHPLVLDPPGPPGKQPL------DAVNMAKCAGFCQAGDTIIV................... 528
286 0.000e+00UniRef50_A0A1Y5FC99 Pyruvate kinase n=1 Tax=Halobacteriovorax marinus TaxID=97084 RepID=A0A1Y5FC99_9PROT  ali  35  1.................MRRAKIVATLGPSSNTIEKITELIIAGMNVCRINMSHGTHESHGELISNIRVASKK-ANKEVAILADLQGPKIRVDKLA--ENLNLENDEIWVIGPTDDKYPEYKGKYIPTIYKDLVSDCFDGARILFDDGLMLAEAIERDRDVY-KIKINVGGVLKSNKGINLPDCDVSAPSFTEKDRADLLFALSQNVDYLALSFVRKKEDIQEVKVLLHDLKVNIPIISKIEKPQAVDNIEGILEVTDVIMVARGDMGVEVGNHLVPSIQKKLIRMCNERGIPVITATQMLESMTHNPSPTRAEASDVANAIWDGTDAVMLSGETASGKYPVETVKTMVQIIETAEETPKVRPFLRNVDLS-----SVHASVMVAASLIGEKIFAKRILAVTESGVSCLKLAKFRPDTPCLGVTTTEETARKMCLYWGIEPFLLNEYKEDSF--NFQEHVINAVK--KSLGLVN-GDKLVITRGDFFTAGSSNSVKVEII 473
287 0.000e+00UniRef50_A0A1G9PR94 Pyruvate kinase n=2 Tax=Pseudomonas TaxID=286 RepID=A0A1G9PR94_9PSED  ali  32  5..................KKVKILATLGPAIHGIDDIRQLVEAGVNLFRLNFSHGEHADHAQRYQWVREVERQL-GHPIGILMDLQGPKLRVGRFAEGK-VHLARGQAFRLDLD---GTPGDARRANLPHPEIIAALQPGMSLLLDDGRLRLRVVAKHAD-AIDTEVVVGGELSDRKGVNVPEAVLDLSPLTEKDRRDLAFGLELGVDWVALSFVQRAQDILEARELIGER---AFIMAKIEKPSAVQQIEDIARLADAIMVARGDLGVEVPAENVPRIQKQIVRTCRQLGRPVVVATQMLESMRFSPAPTRAEVTDVANAVAEGADAVMLSAETASGDYPLEAVSMMSKIIRQVESGPDFQAQLDANRPQAEA--TVSDAISCAIRRISGILPVAVLVNYTESGSSSLRASRERPSAPILSLTPYLRTARRLTVAWGVYSVVNPR------LNEMDEVCRNALELAKSEHMAQPGDTVVITAGVPFGPGTTNNLRIERV 470
288 0.000e+00UniRef50_UPI000D17DBE6 pyruvate kinase isozyme G, chloroplastic-like isoform X1 n=1 Tax=Physcomitrella patens subsp. patens TaxID=3218 RepID=UPI000D1  ali  33  120.............KPSFQRKTKIVCTIGPTSNTKEMIWKLAEAGMNVARLNMSHGDHASHKKVIDLVREYNKEANANVIALMLDTKGPEVRSGDLPQ--PIMLKKGDPFTFTIKRGV---GTDTCVSVNYDDFVNDVESGDTLLIDGGMMSLEVKSKT-HEEVLCEVVDGGELKSRRHLNVRGKSATLPSITEKDWEDIKFGVENKVDFYALSFVKDAQVVHELKSFLKGKSADIHVIVKIESADSIPNLQSILDAADGVMVARGDLGAELPIEEVPLLQGEIIRSCRAMGKPVIVATNMLESMITHPTPTRAEVSDIAIAVREGADAVMLSGETAHGKYPLKAVRVMHTVAMRTEATMPEEEAPSNLGRAFKTHMS--EMFAFHATLMSNTLG-TSICVFTRSGFMALLLSHYRPAGTIFAFTNDKKVQSRLALYHGVRTLHI------NFTNDAEETFVYALSILQKKGMVQDGEEVALVQSGRWRSEYTHHIQVRKV 619
289 0.000e+00UniRef50_Q6NNW4 Pyruvate kinase (Fragment) n=5 Tax=Drosophila TaxID=2081351 RepID=Q6NNW4_DROME  ali  43  1............................................MRVVRMNFSHGSHEYHCQTIQAARKAIAMYVERTLAIALDTKGPEIRTGKLAGGAEIELKTGDKVTLSTKKEMADKSNKDNIYVDYQRLPQLVKPGNRVFVDDGLIALIVKE-SKGDEVICQVENGGKLGSHKGINLPGVPVDLPSVTEKDKQDLKFGAEQKVDMIFASFIRDANALKEIRQVLGPAGACIKIISKIENHQGLVNIDDIIRESDGIMVARGDMGIEIPTEDVPLAQKSIVAKCNKVGKPVICATQMMESMTNKPRPTRAEASDVANAIFDGCDAVMLSGETAKGKYPVECVQCMARICAKVEAVLWYESLQNSLKREIRTSADHISAVTTAIAEAATVGQARAIVVASPCSMVAQMVSHMRPPCPIVMLTGNESEAAQSLLFRGIYPLLVEEMVIGSF--NFRRIMQSGLKLMGKMDILEPGQKVVLV.................. 446
290 0.000e+00UniRef50_A0A0G1QZZ8 Pyruvate kinase n=2 Tax=Candidatus Magasanikbacteria TaxID=1752731 RepID=A0A0G1QZZ8_9BACT  ali  35  1.......................MCTIGPASKETDTLIQMIQAGMNVARLNFSHGTYGDHAQLIAKIRAAAAHCKE-PVGILADLQGPRLRMGYIPD-PGVEVKDHEEVVFDT-AATVYKGRGKPLPLIFPELTRWIKKEDRILIDDGHVEVTVERIQK-KLIKCKVVHGGVIKAHKGINTPDTHLKIASLTAKDKKDVAFLAKQGVDWFGFSFVQTARDVKELRALIARHTPHARILAKIESYQAVRNIEEIIGAADGVMVARGDLGLELPAEEVPILQKRIVQMCVKAAKPVIVATQMLDSMIHSPRPTRAEVSDVANAVIDHTDAIMLSGETASGEYPLQAVKMMARICARTERSHFDDVSLASLIANNR----PDGVFTKLARILAEEAKVTALVASSLSGATGRQLSSFRSEISVYVATNNERVCRQLNLSWGVRPFVVKKC------ETPDELARRSLEYLKAQKIVKKGNRIVLLAGSSVGSGGINMMELKKV 471
291 0.000e+00UniRef50_Q89EE7 Pyruvate kinase n=96 Tax=Bacteria TaxID=2 RepID=Q89EE7_BRADU  ali  30  3................RLRRIKILATLGPASSDLAMIRRLFEAGADLFRINMSHTPHDKMRELVATIRNVESSY-GRPIGILVDLQGPKLRLGAFAEG-SVQLQNGQTFTLDSDKA---PGDATRVNLPHPEILAALRPGHALLLDDGKVRLIAEETSKEHAV-TRVVVGGRMSDRKGVSLPDTDLPVSAMTPKDRADLEAALVTGVDWIALSFVQRADDVIEAKKMIR---GRAAVMAKIEKPQAIDRLADIIEASDALMVARGDLGVELPLERVPSLQKQMTRMARRAGKPVVIATQMLESMIQSPVPTRAEVSDVATAVYEGADAIMLSAESAAGKFPVEAVSTMNRIGEEVERDPIYRSVLTAQRPA--PESTAGDAIADAARQIAETLDLPALICWTSSGSTAVRVARERPKPPIVAITPNIAAGRRLAVVWGVHCVVAEDAR------DQDDMVSRAGQIAFRDGFVRAGQRVIIVAGVPLGPGTTNMVRIASV 470
292 0.000e+00UniRef50_A0SNX5 Pyruvate kinase n=4 Tax=cellular organisms TaxID=131567 RepID=A0SNX5_9EUKA  ali  34  4...................LTKIVCTIGPASCSVEVLKKLIAAGMNVARLNFSHGNYDLMREWFRNVRTAAAEL-NKEIAVMADLQGPKIRCNGFPGG-SIELKHNAEVIIAFSAEDGAPATATIITTKFQPLAERAKPGEHILFDDGYLEVVVERTAADG-VHCRVVVPGVLKPRKGINLPQTDLPLPALTAKDTEDARFVLELDIDFLSLSFVRRPEDIQDLRRIIQEYGKDVKIISKIEKPQAIERLSDIVAASDGIMVARGDLGVEVGNHKVPGLQKRMIREAIARGIPVITATQMLESMINNPRPTRAEASDVANAVWDGTDAVMLSAETAAGNFPVEAVTMMRQILVDAEAQPPSAFSSQGQVQLDSSGTEIGMSMGRTAVELAKLTHSAAIACVTDTGNAAVRVSTCRPAIPIFSFTTSLTTVRRLALVRGCFPILMSRIPEA------EMAFIELERVLTERGCVHEGDRVVYTAGLPLKRATTNTVHIRRV 489
293 0.000e+00UniRef50_A0A1S9CPG9 Pyruvate kinase n=2 Tax=Epulopiscium TaxID=2383 RepID=A0A1S9CPG9_9FIRM  ali  36  7...............INVKKTKIIATMGPSSEQQHVFEHMIEAGVNIIRLNCSYGNYEQQLDRIKMIREY-RNRTKKPIAILLDIRGPEIRTQSFKGGQAM-IQQGAQFILTTRDVV---GTNTICSITYKGLPEDIKVGDKVLINDGIVLLEVKHI-EGTEIVCVVLTGGLIRENARVKVPGVAVKLPSITQNDIEDIEFAINNGVDFIGASFVHGASCVQEIKQILKDKDADIKVISKIGCKDGIDNLDAIIKESYGIIVARGELGLELPIAKVPIMQKRIIEKCNRAGRPVIIATHVLDSMSSNPMPTRAEVTDTANAIYDGADAVMLSGETANGKYPVLAVSTMTEIICAAEQERDYPAILEQKRPY--KELGIAETVSFATCNSASDLGAKAIICPTNSGFTAGMVAKFRPESPIFALVSNKRIQRAINLYSGVEPIVF------AHRGDIEQFMTEAVDILKEEKFIEKDDIVLITAGLPIKSKITNTMKVHVV 479
294 0.000e+00UniRef50_A0A2E5HVY2 Pyruvate kinase n=3 Tax=Chloroflexi TaxID=200795 RepID=A0A2E5HVY2_9CHLR  ali  34  7...................KTAIICTIGPNSDSEEKLSAMMAAGMNVARLNFSHGTTDYHAKVIKRIRTVADTME-LPVAIVQDLQGPRLRIGHFADGAMVRLQSGRQFVITTEDV---QGDSEKVSTDYSDLPRLVDSGDLLLLNDGALELQVESKTK-TDITTRVNVGGSLPARKGINIPKLAVDMGGITKKDLNDLDFGLRQEVDYVAVSFVQNAEDVINVRKAMLDINPHTPIISKLERPGALENLEAIVNVSDGIMVARGDLGVNIGVEKVPSVQKKIIELANRRGKFVVIATQMLESMVHSRRPTRAEASDVANAIFDGADAVMLSAETAVGDNPKDAVAMISEIVREAERHEEEWGHFEEKMSLNQDKL-KALALSRAARELAETLDASAVAVFSRSGSTATLVSKTRPPVPIVAFTTETETYNRIALLRGVVPFVVPR------AMNLEEITRSAEQVLLSQSXIKEGDKIVIIAGLPIDMRSANIVLLYTI 479
295 0.000e+00UniRef50_O05118 Pyruvate kinase n=1843 Tax=root TaxID=1 RepID=KPYK_METEA  ali  33  2...............KRSRRTKIVATLGPASDTPEMIEKLFHAGADVFRINMSHLAREKLPERIEVIRTIEREAK-RPIGILVDLQGPKLRLGTFVGDAAV-LENGQTFVLDSDP---TPGDTDRVFLPHPEILSALEPSHGILIDDGKLRLIVTEVSEGRAV-TRVEVGGRISNRKGVSLPHTVLPVPAMTEKDRGDLEAGLAAGADWIAVSFVQRPEDVAEVKKV---AAGRALVMAKIEKPQALTRLDEIIEISDGIMVARGDLGVEMPLEQVPGVQKRITRVARRLGKPVVVATQMLESMITSPVPTRAEVSDVATAVYEGADAVMLSAESAAGDFPVEAIGTMNRIAEQVERDALYWSILMAQRSEPEPTASDAIAAAAH--QIVEALSLRSIMAWTHSGSTVLRLARARPNASVIALTPKRETARRLTMAWGVHPIVTKD------ASDVDDMAFRAAKFAVRERFAEIGDRVIIVAGVPFGPGATNMVRIAFV 470
296 0.000e+00UniRef50_A0A2H6A001 Pyruvate kinase n=3 Tax=Bacteria TaxID=2 RepID=A0A2H6A001_9BACT  ali  33  8.............TDSRFRRTKIVATMGPASASERVLEDLIHAGVDVVRINSSHGTPQLRARWMELVRSVRERL-GRHVALLVDLQGPRIRVGELS--EPRLLEEGAEVVLAPEAEAQG----EEIPTTYEALARDVKPGTRILLDDGLMTVEVSRVT-GNRVYGVVRHGGTLRSHKGINLPGVQVSAPAVTDKDREDIALAVEHGADYIGISFVRRAEDIGEVRTLV---PQSVRLVAKIEKAAALADLERIVSATDCLMVARGDLGVELPFEQVPLAQKRIIRLANRKGCPVITATQMLESMVQHPRPTRAEASDVANAILDGTDAVMLSAETAVGAYPELSVRAMVRIIGEIERATLEDSGSRRRRSDRTAVDSVEDAIALATCAAAEMLHVPLIVCFTKSGFTARKIAAFRPSVPILGLSTEAGTCRQLSMVWGVIP------EQAHRVPSYEAMLAEARELLVGKGYVRPGDRIVVTAGVPFEPGTTNLLKVEVV 480
297 0.000e+00UniRef50_Q5NR78 Pyruvate kinase n=70 Tax=Proteobacteria TaxID=1224 RepID=Q5NR78_ZYMMO  ali  33  7...............PRGRKVRVVSTLGPASSTAEQIRDRFLAGADVFRINMSHGTHDEKKVIVDNIRALEKEF-NRPTTILFDLQGPKLRVGDFKEGK-VQLKEGQTFTFDQDPTL---GDETRVNLPHPEIFKALDKGHRLLLDDGKIVVRCVE-SSPTKIVTRVEVPGPLSDHKGFNVPDVVIPLAALTPKDRKDLDFALQEKADWVALSFVQRVEDVIEAKELIK---GRAPLLVKLEKPAAIENLESILAATDAVMVARGDLGVECLPESVPPTQKRIVERSRQLGKPVVVATAMLESMIKAPAPTRAEVSDVANAIYEGADGIMLSAESAAGDWPHEAVNMMHRIASYVENAPGYIERVRFTP--TPAEPTTVDALAENASKTAETVGAKAIIVFTETGKTAQRVSRARPVAPILSLTPDAEVARRLGLVWGAQPVQV------STVKTLDEAKKLAAETAKKYGFAKAGDKLVVVAGEPFGAGTTNIVDVIE. 474
298 0.000e+00UniRef50_A0A1V5HUR9 Pyruvate kinase n=1 Tax=Tenericutes bacterium ADurb.BinA155 TaxID=1852922 RepID=A0A1V5HUR9_9BACT  ali  36  7..................KKTKIVCTIGPASDTKEMILKLYQAGMSVMRVNFSHGTHEEQEAKIKIARNFEKEGIYIPCA--LDTKGPEIRTGYMENGA-VPVAAGQAMRVAMSPC---KGNAERFSVTYTSLYDDVKVGDHLLIDDGELDFEVTGKDKAREILVVAKNDHVLKDQKGVNAPFSRLSMPFISPQDEQDLKFGCEHDMDAIFASFTRRPEDIWDIKEILKKYGKNIPVFAKIENPEAVEKIEEIVKAADGIMVARGDLGVEIPPEQVPVVQAKIIKLCRKCGKPVITATQMLDSMTNNPRPTRAEVSDVATAINESSDCVMLSGESASGHYPVQAVEMQAAISRTMEQYLPYEQLAREAYDTSEG--SVNDAIANSIANTALLIGAKLIVNFTETGKSTYRISKARPCCPIISVTNSRTTVMQSAWMWGVYSVLLK----TSMPDFIEEMEVLALKIARDLD-IPAGEPIIIAGGTPTGAGKTNFMRIVNV 477
299 0.000e+00UniRef50_F9Y8A3 Pyruvate kinase n=201 Tax=Proteobacteria TaxID=1224 RepID=F9Y8A3_KETVW  ali  35  2...............KRHRNVKIVATLGPSSSSYAMIRALVEAGADVFRLNMSHGTHDEQRDRYDIIRQVEADL-GVPIAVLADLQGPKLRVGTFADG-PVDLSVGAPFRLDLDP---TPGDIHRVQLPHHEIFAALRPGATLLVNDGKIRLRVDQCGADFA-DCTVTVGGAISNRKGVNVPDVVLPLAALSEKDLGDLEFACQLGADWIALSFVQRAADVEQARALVGDR---AAILAKIEKPAAVDDFDKILAVSDGIMVARGDLGVELPVAAVPPIQKRLITACRAAAKPVIVATQMLESMIESPMPTRAEVSDVANAIYEGADAVMLSAESAAGKFPLEAVGTMDSVATEVESDPHYRELLDSTRKAVR--TTIAEGMVAAAREIADTTDVRAICCYSRSGKTANLVARERPRTPILMLTPLVPTARRMCLSWGTICRMTETVDEFRSAVVAAVRIAV------AENLAEKTDHVVVVAGVPFNVGSTNVLRV... 467
300 0.000e+00UniRef50_A0A0K0Y8Z7 Pyruvate kinase n=63 Tax=Bacteria TaxID=2 RepID=A0A0K0Y8Z7_9RHOB  ali  36  5..................RNVKIVATLGPASDDYKMIRALHEAGADVFRLNMSHGDHAEIKVRHEIIRKVEKDL-NSTISILADLQGPKLRVGVFAKDDGENLEVGQSFRLDLDD---TPGTSERVQLPHKEIFDALEPGAHLLVNDGKIKLRVKECGRDFA-DCEVTVAGQISNRKGVNVPDVVLPLAALSEKDLKDLEFVCELGVDWLALSFVQRAADVEQARKL---ANGRAAILSKIEKPSAVTAFDEILAVSDGIMVARGDLGVELPVQNVPPIQKQLIRKSRAAAKPVIVATQMLESMIESPMPTRAEVSDVATAIYEGADAIMLSAESAAGDFPIEAVTTMNNVAVEVEADPTYTQIIEASRKTS--GRSVADGIVAAAREIAETADIKAICCYSQSGTTALLTVRERPRVPIIVMSSDIKTVRRLALSWGTNCVMTDKVVNRFKT-----AVLEAVRSALSTGVAEKSDLVVVTAGVPFNPGSTNILRV... 469
301 0.000e+00UniRef50_A0A0G4J9Z9 Pyruvate kinase n=26 Tax=root TaxID=1 RepID=A0A0G4J9Z9_9BURK  ali  34  6..................RSTKIVATIGPASSTPEVLSRMIAAGVDVVRLNFSHGKAQDHIERAEMVR-AAAKAAGREVAIMADLQGPKIRVGKFENGKT-TLEAGAKFILDAD---CELGNDERVGLDYKELPRDVRPGDVLLLNDGLIVLIVDRVL-GSEIHTTVKVGGDLSNNKGINRQGGGLTAPALTAKDMEDIKTAMALGADYVAVSFPKNATDMEMARRLAEPYGIKPRMIAKIERAEAIPALEEILAASDCIMVARGDLAIEVGNAAVPGLQKRMIKLAREMNKLTITATQMMESMIHNPVPTRAEVSDVANAVLDGTDAVMLSAESAAGKYPVETIETMAAICVEAERSETVELDRDWLNQ---TFTRIDQTIAAGALFTAYHLGAKAIVALTESGSTALWVSRHRIHVPIFALTSQLGSHRKMALYRNVYAMRADA------TLDRDQALKQAEQLLLARGVVKRGDTIVLTVGEPMGPGGTNTLKIVQV 477
302 0.000e+00UniRef50_A0A0G1KIQ2 Pyruvate kinase n=2 Tax=Parcubacteria group TaxID=1794811 RepID=A0A0G1KIQ2_9BACT  ali  36  3IARIRHKSLIK-----RFTNTKIVCTIGPSSESREVLRELIISGMRVARLNFSHGSHEHHRLLIENLRKISDELS-LPLAIMQDLQGPKLRVGSLA--RPVELTSGEEVILVKEDGLLSEGRGKLVPLQC-DLAKSVAKGDTILIDDGLVELSVHHVRAN-LITARVLVGGAVGSHKGINIPGKNIGGETITDKDKDDARFGVKLKVDCVALSFVCKADDITHLRRILGDRDTPPFIIAKIERALALDHIDEIIDASDGVMIARGDLGLEIDASRVPLIQKEIIGKCVERGKPVIVATQMLDSMMRNPRPTRAEASDVAGAVVDHADALMLSGETAFGKYPALAAETMVKIIHEVEESRYD----DMPLPSYSEPSDKEDAIARAACALASEVSARLILVTTISGHTARSISRFRPPIPIIVTCDSAEIQRQLVLSWGVIPFLLPKFRS------IDSLITAAVLKAKESGIARNGDYIVLVSGQPVGIGGANLIKVHKI 491
303 0.000e+00UniRef50_F5Y6W3 Pyruvate kinase n=3 Tax=Treponema TaxID=157 RepID=F5Y6W3_TREAZ  ali  38  4.................IRNTRIVCTMGPAIKTMEMTRSLIRKGMNIARFNFSHGSHEEHAMRIVMVREAAKA-EGVPVALILDTKGPEIRTGVIKDDGAIDLKTGTLIDIIAEEDAAKYSTTKCITVSYKLLAEDIKKSVKILIADGLIGLDVLNV-EGRIIHCNVSNGGELGSRKNVNVIGVHTRLPAMSERDQADLLFGHQQGMDFVAASFIRKGQDVISIKKYLTSIGSDMPVISKIEDEEGLDNIEEIIRVSDGIMVARGDMGVQIPPERVPLEQKRIISLCNSEGKPVITATQMLDSMIHNPRPTRAEAGDVANAILDGTDCVMLSGETSAGAYPELAVEVMDRIARTTENSEACGESLDSHRIFPRHGCDLGEVIANSASETADSINAACIIVPTLSGHSAQLISRFKPRRPIVAAASNDSVARRLLLYRGIVPVGVQK------VDDSEAMIQGAITAAIREGFAGLADKVVVAAGLPVNSPFTNSIRIHVI 498
304 0.000e+00UniRef50_A0A0G0M2C6 Pyruvate kinase n=7 Tax=Parcubacteria group TaxID=1794811 RepID=A0A0G0M2C6_9BACT  ali  36  1.................MKRTKIVATIGPSSNKKEMIRELIKNGADVFRLNFSHGKHEDFFRIIKIIRSLEKDLK-RPIAILQDLQGPKIRVGEI--DGKIILQKGEIIKI-----AETQEDEKTIPME-KFIIKNLKKGDEILIADGTIKLEVASIKKKLEIFCKVIASGEIISFKGVNLPGIKIDIQPLTEKDERDLEFGLENGVDFVALSFIKNADDLLGVRKII--HHKMTKIIAKIETPEAVADLDRIINVADAIMVARGDLGIEISLENIPRVQKEIIRKCNANAKPVITATQMLGSMVKNPLPTRSEVSDVSNAVLDGTDAVMLSEETAIGAYPQEAVKMMSKIIKESEKIFPFGNLLPN-KKEFAISDQVTLAIGDGINHIIKDLDVKAIVAFTESGWTSKVISAFRPSQPILATSSHIEVLRQLSLNFGVVPV------KALSLKSTDQMVRQARNIAIKSGLVKRGDKIVISAGIPFGHGSTNLILVQV. 472
305 0.000e+00UniRef50_A0A2E3V4G2 Pyruvate kinase n=15 Tax=Bacteria TaxID=2 RepID=A0A2E3V4G2_9RHOB  ali  36  3................RLRNVKIVATLGPSSSDYNTIKELFEYGADVFRLNMSHGSYDNIKDRHTIIRKLEKKYS-RPIAILADLQGPKLRCGIFKNE-SIILEKNDKFSFDLEDV---PGDQKRVYLPHKEIFKTIRKNEPILVDDGKVKLRVQSVKNG-IIKCLVENGGTVSNRKGINVPETLVPMAALSAKDKKDLEFVCDLGVDWLALSFVQTAKDIIEAKKLIK---GRTSVISKIEKPSAVTDFEAILANSDGIMIARGDLGVEMPVQAIPPIQKRLVMACRQFAKPVIVATQMLDSMVDSPMPTRAEVSDVANAIYEGADAVMLSAESAAGAFPIEAVKTMDSIAIEIENDPTYRKIMDNSR--FRQKETVADAITVAAREIAETTPVTAICCFTHSGATAKLVSGERPRVPIIALTPLIKTARLLCLYWGAHCVI------TGHVDRFKMAVINAARAAKKYKFANIDEQIIVTAGVPFNPGSTNIIRVSPV 470
306 0.000e+00UniRef50_E1X5H1 Pyruvate kinase n=18 Tax=Proteobacteria TaxID=1224 RepID=E1X5H1_HALMS  ali  36  1.................MRRAKIVATLGPSSNTVEKISELIEAGMNVCRINMSHGTHDSHKEVIANIREASTKV-DKQVAILADLQGPKIRVDKLT--ENLNLENGEEWVIGPTKLMGDEYKDKYIPTIYENLVDDCFDGARILFDDGLIMAEATSRDRDVY-KIKVSVGGVLKSNKGINLPDCDVSAPSFTDKDREDLMFALTQNIDYIALSFVRKGEDIQKVKVLLHDLKVDIPIISKIEKPQAIDNIEGILDVTDVIMVARGDMGVEVGNHLVPSIQKKLISLCNERGIPVITATQMLESMTNNPTPTRAEASDVANAIWDGTDAVMLSGETASGSYPVEAVKTMVKIIEDAEQTPKERPLLRHVDLS-----SVQASVMVAASLIGEKVYAKRILAVTESGISCLKLAKFRPTTPCLGVTTTEKTARRMCLYWGIEPFLLKNYREDSFNFQY-----HVINKVKKKLGLVNGDKLVITRGRFFRAGSSNSVKVDII 473
307 0.000e+00UniRef50_A0A1F6QE59 Pyruvate kinase n=2 Tax=unclassified Candidatus Melainabacteria TaxID=1897007 RepID=A0A1F6QE59_9BACT  ali  37  2...............PTSRLTKIISTIGPASQEPDTIGKLIDAGTNVFRINCSHSDLPVREKVIKHIRELSIK-AKREIGILLDLQGPKIRVGKLKDG-SINLRDRKNVFLTAENII---GTEEKFYVHFEQIINSLKAGHRILLNDGIIELRVHKILDKKNIECEIIFGGELNDGKGVNFPDTLLDVPSITEKDIEDLKHGLSAGIDLVALSFVRSAQDIVTLRNYF-PKNSIIKIIAKIEKPQAIDDLDNILKASDGIMVARGDLGVELPYEQLPAIQKRIIQKANQNNVLVITATQMLESMINSPRPTRAELSDVANAIFDGTDAIMLSGETAVGKYPALAVQTMHKVALAAEGVAPRYRH---------DVSSVQENLARITCELAERVKATAIATFTLSGKTANLVSKQRPPVKVIALTQNEVVSRQLSLYWGITPILLTDVT------DTETMMYLVEKTLMEKGFIKKGDLVIVTGGLPIAAGESNFIKIHK. 467
308 0.000e+00UniRef50_A0A2D9QUQ6 Pyruvate kinase n=8 Tax=Candidatus Poribacteria bacterium TaxID=2026781 RepID=A0A2D9QUQ6_9BACT  ali  34  2................NXKRTKIVCTIGPASRSVELIKSLVVSGMDLARISFSHDTHVEHAETIKNIKTAEAXL-GIRIPILQDLSGPKVRIGTFESG-SVELVEGSRFTLMAE---QTAGDVTKVSVNSPEFINALSVGDRILLADGEIQLQVISTAI-TSIXCVVVAGGELSSKKGITVPGVGLNVAIPTPKDIEDLXFGAELGVDWVAQSFVRNVDDVKNLKSILAQYEFDIPVIVKLEKKEALDDLEGIISEADGVMIARGDLGLEVPLAQVPAWQKKITKLTNDQGKPVITATQMLESMVNYPRPTRAEVTDXANAIIDGTSALMLSAETAVGRYPTASVQMMTEVALATEXEIDYLGSFKPI----TIGGEIPDAIVHSACHTALEIGAKLIICCTRYGDTARQVSKYRPFAKIAVVSPYEQTLRKSMLYWGTSAV------TTEYAEGIDQMINESKASILKAGLGHPGDRVVIVGGMPV--GSTNMLK.... 463
309 0.000e+00UniRef50_UPI000640C800 pyruvate kinase PKM-like n=1 Tax=Hydra vulgaris TaxID=6087 RepID=UPI000640C800  ali  46  22MTRGEYLSLLNIDQPPTVRGTGIICTI-------EFI-----------RIN---------------VCVSENKLFIK-----------QTKTIPVIQGGEVTYVKGQELKVTSDPYFKNQCSESLLFLDYPDLIHSVKCGSKIVIADGNFLLEVKEIIDNNNLLAVVLNDATIGSRKNCNLPGAVIALPAVSEKDKQDLLFGVKNKVDMVFASFIRKASDVAEVRNALGEEGKSIKVIAKIENYEGVVNIDEIITAADGIMVARGDMGMEMPAEKVFLAQKILITRCNRAGKPVICATQMLESMIKNPRPTRAEITDVGNAVVDGADCVMLSGETANGAYPIEAVAVMHKICRQAATVQFYKESFSEHLNKNY-VTDATETTCIAAVAASFKALASAIIVLTTSGRTSWIMSKYRPQCPIIVITRNEQVARLCHLYRGLFPLVYSTPRIKTWHEDMFDRLEFAITYGKDMGFIKTGSSVVFVSGCQPGTNSTNTVQIIQV 477
310 0.000e+00UniRef50_A0A1F5KKJ7 Pyruvate kinase n=1 Tax=Candidatus Daviesbacteria bacterium RIFCSPHIGHO2_02_FULL_43_12 TaxID=1797776 RepID=A0A1F5KKJ7_9BACT  ali  33  6..................KKTKIVCTIGPSSWDYSVLKQLALAGMDVARLNFSHGTHAEKAAQIVLVRRISREL-DKPLAIIADMQGPKIRIGQLSEEPVIILKQGEKIHLSISPI------SDEVPM-YFDLSPFVKKGHRILLNDGLVEAKVTEIN-GKVIVAVVQNDGYISSHKGVNVPDTRLPGASLTPKDYEDAEFALKAGVDFLAISFVQSPEDLKKARDLIKKYSPKTKLIVKLEKPQAVENLEEIVRATDAIMVARGDLAIETDVAEVPLVQKRIIRLARQYFKPVIVATQMLESMTENPRPTRAEVSDVANAVFDQADAVMLSGETANGKYPVKTVKMMNDICLTVEGHTEYKNYVGIDLEDVDGKELANRAIASAGVVLAELANVKLIIAGTVSGKTVQSLSSFRPQADIVAICNDSEIRNQLVLVWGVRPFDIKIETQA------EAFWNHALELIKKNKLASKNDQVIILSGPVPGVGGTDTLKLET. 491
311 0.000e+00UniRef50_A0A178U603 Pyruvate kinase n=1 Tax=Arabidopsis thaliana TaxID=3702 RepID=A0A178U603_ARATH  ali  39  1.......................................MIGAGMNVARLNMAHGELQDHGDRITRIRQAAGEL-NALVPILMDIKGPEVRIGKLAEPG--ELKAGEKLTLTTEIIV---GDTRRISVNYANLPSDVKPGNRILIDDGLIELTVDSVT-DTEIECVIVNGGMIKSNKGVNLPGIHTSLPGVTERDIMHIKYGVEQKVDIIAPSFVRRAEDIWQIRGMLEELGPHIQIISKIENQEGVTNLDSIIEASDGIMVARGDLGVEIPVEEVPMIQREMIEKCNRAGKPVIVATHMLDSMQVNPRPTRAEVSDVANAVIQGTDSVMLSGETAAGKYPVESIATMANIAIKAESMLDYTEQFK--KRSQVQPATTTEIISQAVVSSSLELGAKAILTPTESGFTARMVSKYRPKAPVIAIAYDDNVLMRLCLLWGVIPVRGEKE------ESTDAVFASAVHNGRKTGLLTSGDHVVISAGTPIGK........... 436
312 0.000e+00UniRef50_A0A2E6VW03 Pyruvate kinase n=1 Tax=Myxococcales bacterium TaxID=2026763 RepID=A0A2E6VW03_9DELT  ali  37  1.................MRRTKIICTIGPASDSKEQIKALATAGMNVARLNFSHGDHDYHRKIAARIREVAEEM-GLPLAILQDLQGPKIRSGRMKDGG-VDLIDGRRVTITTEDVI---GTADMFSTTYKNLPQDLSSGDVVLLDDGKIRLSVQSI-EGLNVHCEVECGGRLTDRKGMNLPGVTVSEPSLTDKDLVDLKFGIELGVDAVALSFVRSARDIRLLRRELVSASVRPVVIAKLEKPEVLEQFEGILDEADGIMVARGDLGVEVPAERVPMLQKEWVKRANHRGKITIVATQMLESMIHNERPTRAEASDVANAVLDGSDLVMLSGETATGSFSVEAASMMNRIICDTEQSSRYPYENISQRLDLFSAQAHQNALALAAVRAAKDLGAKAIVVYTTSGATAQLVSQYRPSVPIVAFVPNATHQNALSFSWGVQSRILPTENQXXXXXXXXXXXXXXXXXXXXX------ETIVLLTKVPLDKGRTNTMLLHVV 472
313 0.000e+00UniRef50_A0A2M7TPW3 Pyruvate kinase n=1 Tax=bacterium (Candidatus Torokbacteria) CG_4_10_14_0_2_um_filter_35_8 TaxID=2014297 RepID=A0A2M7TPW3_9BACT :  ali  36  1.................MRRTKIVCTIGPSTFSYNILLKLAREGMDVARLNFSHGGYKEAREVIKNIRIISKKV-GKPIAIIQDLQGPRIRTGDLKKE--IKVQYGDEVFISCQGVKDNK--DKVIPITYPDLYKDVKKKDRILIDGGMVELEVVRV-SNKTIKCKVITGNVIKGAKGINVPTTSLSITSLTEKDKKDLEFGVKNDVDFVALSFVRKAKDVKDVKKFLRDRKGDIKIISKIEKHEAIENFDEILTASDGIMVARGDLAVDIPQEEVPLVQKEIIRKCLLAGKPVITATQMLGSMVTNPRPSRAELSDVANAVLDRTDATMLSEETAIGDYPVKTVEVMDKVAREAE-------LLQEPFSSKEICYHTPSAISKAACKLAFELSASLILAFTSTGFTAKTISRFRPRIPIIALTPYKKVYYQLSLSWGVMPYFFP------FGDNLDDAIGEAGKFIKKKKLITKKSKIIIVTGHPLRSGDTNLIKVQEI 490
314 0.000e+00UniRef50_A0A1W9PEI5 Pyruvate kinase n=1 Tax=Thermotoga sp. 4484_232 TaxID=1968524 RepID=A0A1W9PEI5_9THEM  ali  35  1.................MRRTKIVCTIGPVTGSKEMIEKMIDAGMNVARLNTSHGDLEDHRKKIKLLKEVRKE-KGVPLAILLDLAGPKIRTGYL-NEDYVELEEGQVFYLTTEEMI---GNREIVSVNCKELARDVKKGDRILLSDGAIELEVLET-DGVKIKTIVKNGGRIT-------------------------------HVDYFAVSFVRKKEDVQKLKDILKERNCDIPVIAKIETKQALQNLEEIAKVSDGLMVARGDLGVEVPIEEVPMAQKRIIELANRLAKPAITATQILESMVNNPRPTRAEITDIANAILDGTDALMLSDETAVGKYPIPCIKVMDCVARKAEESLFYRHISLDWLRSFSTVYDISDAISHACWQLSEDLGVKLIITSTSSGSTARRVARFRPKSLIVATTPFEKTYHRLSLVWGVLPLIIDE------VKTTDDLIEKSLKKVKERKLAEEGDVAIVTAGIPPGPGTTNMVKVQKV 442
315 0.000e+00UniRef50_A0A1F7NHL3 Pyruvate kinase n=2 Tax=Bacteria TaxID=2 RepID=A0A1F7NHL3_9BACT  ali  34  1.................MRRTKIVCTIGPASASADVLDRLVGAGMDVARLNFSHGDYAWHAEVIHRIRE-GQARWGKPVAILQDLQGPKVRLDRFEGGG-VELKTGATFTLTSRAIL---GTAAHVTISEPALLAELKAGDQVWLADGLVQLTV-EAMEGGDARCRVSAGGPVGDHQGVVLPRGMRATSCLMPKDREDLKFGLEHGVDYVAVSFVRSAADIQEVRKVLRDRGAEVPLIAKIERAEAVQNLGGILPLVDGVMVARGDLGMEVPLEEVPLIQKEVVRQARLAKVPVIVATQMLESMVEHVRPTRAEVSDVATAIFERADAIMLSAETATGKHPVETVEVMARIAERVERSV---APPVWERRRQGEVQGFPQAIAEAACHAASDLGAKAIVAFTQSGSTARFISQERPEAPIIALTPSAEVQRRLTLCWGVSARLIRKVGS------TDEMLEEVEATLLGDGSVRVNDVLVIISGAPMWVGTTNLLKLHRV 469
316 0.000e+00UniRef50_A0A1Q7PD94 Pyruvate kinase n=43 Tax=Bacteria TaxID=2 RepID=A0A1Q7PD94_9BACT  ali  36  1.................MRRTKIVCTIGPASSSTAELDRLVGAGLDVARLNFSHGTHDEHAEVIRRIRE-GEARWGRPVAILQDLQGPKIRLGTFGPGGGVDLEAGRTFTLCARPVV---GTVERASLTHPEYLKDLRPDDEIWMDDGMIQLRVEAVSPD-EVRCRVVVGGRISDHKGLSLPRVTLPVSCLTPKDREDLRFGLRQGVDFVAVSFVRSADDIDAVRSVLREAAGDLPIVAKLERHEILANLPGILNTVDAVMVARGDLGVDVPIEDVPHIQKEIIRQARGAKVPVIVATQMLESMVTHIRPTRAEVSDVSTAIFDGADAIMLSAETATGRYPGEAVSVMARIAERADGAV----LAVERERRRRPGGSFPEAISDAAATAAHVLGARAIVAFTESGFSARLISQARPGVPIIALTPFVEVQRRLALSWGVISRLIRK------VETTDEMIEEVEATLLNDGSVRPNDVIVIISGSPMWVGTTNLLKLHRV 472
317 0.000e+00UniRef50_A0A2D6E260 Pyruvate kinase n=6 Tax=unclassified Bacteria TaxID=2323 RepID=A0A2D6E260_9BACT  ali  35  6.................MKKTKIVATIGPASEKRTTLESMVRAGMNVARLNFSHNTHTHHAMLVRNLRYVSKK-TGRAVGILQDLQGPRIRLGNLPDEG-VKLKAGQMVKLVAEDSGESKSNQVILPMQYPELYKDLNSKARILIDDASIELTVLGIR-GRVVETKVKTGGVAKSHKGMNFPGSDIKCPPVTKKDALDLAWGIEQGVDYIGLSFVKSPEDVKRLRRSINPAGVGPKIIVKIERREAVQDFASILAETDGVMVARGDLGIELPPEDVPLIQKEIIRQCNRAGKPVIVATQMLQSMTAAPLPTRAEVSDVANAILDGTDAIMLSGESASGKYPLKAVQVMDRVADEVEGKVVADRQFHRVRTTALQPQETSEAIALATKEVSDTIDAKAIVCATITGRTPRLVARYRPEVPVIAMTDQDFTMRQLALVWGVQSYKIP------FIGSVEELNKAVTKVAR---LAEIGTSVVVVAGDPMGPVPPNMVKVLEV 502
318 0.000e+00UniRef50_A0A261Q0M2 Pyruvate kinase n=20 Tax=Bacteroidetes TaxID=976 RepID=A0A261Q0M2_9BACT  ali  35  2...............PYQKKTKIVATVGPASQSKEMLLKLAQSGANIFRLNFSHGTHADHLSRIQAIREINAEH-GLNLTILQDLQGPKIRT-QLVENNGVELVAGNPLTFVMDENLL--GTSERVGTTYTSMYLDVKPGERILMDDGNLEVLVESIDDKKEVLTKVVYGGILKSKKGINLPGTKVGLPALTEKDEEDLIFGLEHDVDWIALSFVRSAEDILAVKEKIKARNGRSKIIAKIEKPEAVEVLDAIIEATDAVMVARGDLGVELDGAMVPELQKTMIRKCIKQAKPVIVATQMLESMTSSPRPTRAETSDVANAVLDGASATMLSAESASGQYPIEAVSTMTHIIEAVEEYGDESAIYFKNHMLKGEENSPTDRVIAAACRLARDVQAKAILCITNSGYTAYRLSSHRPKADIFVFSADENLMTQMGLLWGTRVFNYDSAN-----LSTEQISHDIAKILVKQGHLQKGDVFVTLLSVPAQQDRTNTVKMGVI 492
319 0.000e+00UniRef50_A0A1F6PPQ1 Pyruvate kinase n=4 Tax=Cyanobacteria/Melainabacteria group TaxID=1798711 RepID=A0A1F6PPQ1_9BACT  ali  35  2...............TKFIKTKIIATIGPSSSSDEKITELIKTGAKIFRINSSHGTAELHKESIEKIRRISKEL-NEFIAIILDLQGPKIRIGNLS--EPVELKKDQEIILKPCLESDESG---VLPVDYPEIIKDVKNDDHLLLDDGKIEFIITEMFPDK-IKARVVRGGLLKSRKGLNIPNSSKSVSTVTERDIGYIKFAVTNDIDYIALSFVRDKDDIIAAKNYLKQFNGNIPIIAKIEKPQAVENLESIIHVSDGVMVARGDLGIEISPELVPIVQKTIINEANIHRKPVITATQMLESMIEQPLPTRAEASDVANAIIDGTDAVMLSGETAVGQYPTEAVEMMAKIANNVETS--NLGHFNQVPKINDDVYELSQAIASAVIKMIPEVEIAAIVALTRTGYTAKLLSKSKPTIPIISISDDERVCRRLNLFWGVYPYKMTLHPNF-----TEEMLKEIDSILVKETFLNSGDKVIIAGGLPITAGKTNFLRIHQ. 474
320 0.000e+00UniRef50_A0A1V6D2F7 Pyruvate kinase n=4 Tax=root TaxID=1 RepID=A0A1V6D2F7_9BACT  ali  34  4...................RTKIVATLGPASSSLDMLRRLVRAGCDVFRVNFSHGTHEQHAESLRLVRQIEDE-TGSPLAVLADLCGPKIRV-SPIGGGSVLLAEGQTLAIQREPII---GQADRISTTLAELVDEVQVGESVLLDDGRIRLEVVEVRPGREVVCRVVAGGILSSGKGVNLPGTKLTLSALTEKDHRDLAWLVQRDFDYVALSFVRRPEDIQALRDRLGELKADLHIVAKIEKPQALHNLEPIVEASDAVMVARGDLGVEMSLPAVPVAQKMITALCHRLGKPCIVATQMLESMIQSPTPTRAEVSDVANAVMDAADAVMLSGETAVGKFPAESVAMMNRV---VEDIQAYHDLHCPPQDVAFAPARTAAALAGAVREIIRIEDIKAVAAFSMSGLTARMFAKHRLRCPILGISPDRRTLRRMGLYYGVIPVQASRMQY------TQELLDLAQQVVLDREIAAAGEKIVVVCGRPLGSGKTNTLIVHTI 471
321 0.000e+00UniRef50_Q6MLB5 Pyruvate kinase n=16 Tax=Bdellovibrionales TaxID=213481 RepID=Q6MLB5_BDEBA  ali  35  5..................RRAKIVATIGPATRDEKNLEKAIKAGMNVARLNFSHGSHEDHLKVVHSLRKLSKELQ-APVAILQDLQGPKIRVGKFENG-SIEIKPGEKLVVTTAKVLGKPG---LVPSDFQELPLACVPGTRILLDDGLMEVKVLQVR-GEEIDVEVVYGGILKDRKGMNLPGVNLPVDCMTPKDLEDLQFGIANKVDYIALSFVRHARDIRKLRELIEAGNSNAKIVAKIEMVEAIENLEEICRLSDAVMVARGDLAVEVGQSRLPGYQKRIISVCNQLGKPVITATQMLDSMVENPRPTRAEITDVANAVLDGTDALMLSAESASGKYPFKCIRTMHEIITEVEREEYYKISLENEFLSTPASIAASA------SLSALKLNATAIICLTTSGKTANIISAFRPKARIISVTQHLDVLNGMELGWGIQTHAIKPY------KTMEDILREVDLLLVSHGLGKTGDRVILTLGQPIACGKTNSIYVHTV 471
322 0.000e+00UniRef50_K1QRW8 Pyruvate kinase n=2 Tax=Crassostrea gigas TaxID=29159 RepID=K1QRW8_CRAGI  ali  39  4.TRLEHMCKLEIDQPGHQRLTSIIGTIGLACDSVETLREMMKAGMTICRLNLAYRTHEYFNGVVKKIREAEASLEIIQVGIGIDITGTGIRVGSLVKDQELKLKAGDKMRFSIDEQYRDNGNESVMFIDAALVFSQIKTGSTVIIEDGPLTFVIKEKGED-YVDCEVEEPGDLGSHMMWTIPNMVMREAELSEKDKKDLQFAVDHDLDMVFASWICSPEMVEEVRKFLKARSKSMKILAKIETQTAIRRVDEIMAVADGLYLARGNLGIHISPEKVFLAQKMLIGKANKAGKPVICATQMLGSMMHNARATRAEVADVANAILDGADCVMLSRETARGKYPLRSMQTMSAVCTEAEAAIFNEDLFYALRHKV-GVTDNTHTTAIAAVEAAHKCHAKAIMVVTVSGRSAALISKYRPDCVIVAITRSKHTAKSLQLHRGVFPVLHTDSKDQVWADDVDARLHHGISMARRNGYINSGDMLVLVTGWTSGVGSTNTIRVVT. 505
323 0.000e+00UniRef50_I0GJ83 Pyruvate kinase n=4 Tax=Bacteria TaxID=2 RepID=I0GJ83_CALEA  ali  36  9...................KTKVVVTIGPSSESPEIVREFFNLGVDIFRLNFSHGTHEDHLRRIKIIREIESEF-GYSASILQDLQGPKIRLGTFKSGE-VILKEGDSFIITKKEVL---GDERISTITYKEVIDEVNIGDFIYINDGLIKLKVTGKAND-EIETQVIQGGPVSDHKGVNFPTTKLTIDPLTEKDIDDLRFGLQNGVDMVALSFVKTKEDVLKLKSYMGKFGRVVPIISKIEKWEAVENLQSIVEESQAVMVARGDLGVELPIEKIPLIQKEIIRITNNLGKPVITATQMLGSMVEEQFPTRAEVTDVANAIFDGSDALMLSNETAAGKNPTLSLKMMRSIIKEIEESVLFKDNLRKL-NSQILEINVPEVLSKSIKDISELLDIKLIIVATESGKTATLVSKYKPQVPILALTPKDETLRFLNLKWGVFAYKVRNYSS------VDEILNEAPTIATTLGLLSKGDRYIIVCGTHTGSGTTNLIKVDVV 477
324 0.000e+00UniRef50_A0A1G0SEL3 Pyruvate kinase n=1 Tax=Ignavibacteria bacterium RBG_16_34_14 TaxID=1798433 RepID=A0A1G0SEL3_9BACT  ali  33  11...................KTKILATLGPNSYTSDDISKLILVGMDGVRLNFSHGNYEFYEKVFNNINEACVD-EKTLLAILIDLQGPKIRIGELA-EPEIEITTGENIEITCENI---KGTKEKISTSYMRLGDDAIIGDQILIDDGLIRLRVIEKKKD-SLFCIIENGGILKPRKGMNLPGMKISTPSITEKDYRDLEFAIKHRVDFIALSFVRSAADITTLKEWLKGKDKLRPVIAKIEKKEAVDNFDEILEVSDGIMIARGDLGVELYPQEVPVIQKMIIRKCNSIGKLVITATQMLESMINNPVPTRAEASDVANAVWDGTDVVMLSGETSIGKFPLGAVQVMNDIVKNTELHLKPQQEI-DLKIPEMVEENLFDSVGRAITGISRQVNAAAIVAFTFKGRTAINLSKFRPKAKIIAFSNSFDTMNNLCLRWGVTSIYMDEIDKEKIA------IDKAKKLIVEYGHVKQGDIVIFTAGAPSEKSRANWLRFEVI 479
325 0.000e+00UniRef50_A0A2E7YZD8 Pyruvate kinase n=9 Tax=Alphaproteobacteria TaxID=28211 RepID=A0A2E7YZD8_9PROT  ali  35  5..................RKAKILXTLGPSSSSPEVIEALFNEGCDVFRLNFSHGSIEDHRKNCQAIRKLEKKY-NHATXILADLQGPKLRIGIFKDDK-IQLKKGQGFTL---DLITTPGDQTRVNFPHPDIYDILTPNTEILVNDGRVKLQVIEQSKD-ELKTEVLNDGVISNNKGINIPGIILPISSLTTKDKSDLSKAIEMGVDWVALSFVQTSKDIXELRKIVS---NNVSVMAKIEKPSAVKNIDDILDXSDGVMIARGDLGVELPTEKVPVIQKNIINRCRDFGKPVVVATQMLESMXDHYXPTRAEASDVAXAIYDGADAVMLSGESAIGQYPIESVITMNKIIESVEKDXNNFDLXIHEEKXRQKTISTTDAITSAAYTVARNAEAKAVVTFSVSGNTALRMAKERAPVLGIGLSPNIKTARKLQLVWGVHSCHTKD------AXNTTEMVQIACSVIKEKKLGLPGDTVVITAGVPFGAGSTNLLRIAKI 472
326 0.000e+00UniRef50_A0A2H0QDC7 Pyruvate kinase n=3 Tax=Proteobacteria TaxID=1224 RepID=A0A2H0QDC7_9PROT  ali  36  5................NMRRAKIVATLGPASNTVEMIEKLINAGINVARINMSHGTHEGHAQTIKNIRQASKNIK-KEIAILLDLQGPKIRVDKLP--TPLELKNGEDWVIGPSKEKYPQYKDRYIPTIYEKLVDDCHDQARILFDDGLLRATAI-KRDGDVYKIKVDVGGMLKSNKGINLPDCDVSAPAFTEKDREDLLFGLKQDIDFIALSFVRKKEDILQVKYLLHSLKVNIPIIAKIEKPQAIDNLPEILKVVDVIMVARGDMGVEVGNHLVPSIQKKIIMMCNEAQVPVITATQMLESMTENPTPTRAEASDVANAVWDGTDAVMLSGETANGKYPLETVQMMNSIILEAERTPKERPLLRNM-----DLTNVTSSVMVAASMIAEKIYARYILSITESGSSCQKIACFRPNKEVLGITNNIRTVRRMSLYWGVTPFQLIDFNEDNFNFQV-----MVIDKVKTKLNLVNGDKLVITRGDFFARGSSNSVKVEII 478
327 0.000e+00UniRef50_A0A0P1AFR4 Pyruvate kinase n=1 Tax=Plasmopara halstedii TaxID=4781 RepID=A0A0P1AFR4_9STRA  ali  40  425............PRSSKFSMTKIVATVGPASEQLEMLQNLTDEGLRIMRINFSHAEYDEALQRIKNLRAAEGMAKFNLRAVLHDTKGPEIRTGKVRDGKKIKLEKGKSVVVTTDPAFENQGTADKFFVSYQKLSETVKVGDTVLLSDGLIRLTCTSVGKG-EITCHIHNTEEIGNRKGVNLPGLVVELPALSEKDKRDLDWGVKHDIDFIAASFIRKASDVIEIRRFVDECVKRPKIISKIENLEGVQNFEEILEASDGIMCARGDLGVEVPAQKVLTYQKMMVDRCNAVGKPIIVATQMLESMQNNPRPTRAEVSDVGNAVLDGADCVMLSGESAQGKYPVESVATMNTVIKEADELLL-NPTYQAKFQFDSPTSDVESAVS-SAVKTANEMHAQLLIVLTRTGYTARKVAKYKPTVPVMCFTTDLKVGRQLQIHRGLYPVVPDNVNRAPTT-------AEAISHAKKMGWLSSGDRVVVISGDKL............. 904
328 0.000e+00UniRef50_A0A2E3GN38 Pyruvate kinase n=1 Tax=Saprospirales bacterium TaxID=2026790 RepID=A0A2E3GN38_9BACT  ali  34  8...................KAKIVATYGPSIADEAILEELILSGLSVVRFNFSHGDRSFHKEGMATVRKLNQKL-GSHVAILGDLQGPKIRIGEV--DGSIELITGEQVVIHPNEA---PCTIQNLTVRYPTLLKDILPGERILINDGRVEIRAIEKRGDG-ILCDIIEGGVLTSRKGVNFPDSKLSVPTLTEKDEEDLVFAMEQEVNWVALSFVRNANDLIGLKKRLGELNSFIKVIAKMEKPEALQNIEEIVKASDGVMVARGDLGVEIPQEQVPLAQKNIIQTCIRHAKPVIVATHMMESMIESPVPTRAEINDVANAILDGADAVMLSGETSVGKYPVKTVQTMRAILDSIEA---RGHIFNKTRQASATSESESDALCNAACHLAQQVEAKAIIGMTKSGYTAFMIASTRPVAPVYIFTDNRPLLNTLNLLFGVHAFYYDGNSG------TDETIEAVIDILMLHNFVAPEDLVVNLASMPFYKGRTNTIKITKV 474
329 0.000e+00UniRef50_D0N8B7 Pyruvate kinase n=15 Tax=Stramenopiles TaxID=33634 RepID=D0N8B7_PHYIT  ali  41  27............PRSSKFSMTKIVATIGPVSEQLDMLQKITDEGLRIMRINFSHAEYDEALLRVTNLRAAEGQAKFNLRAVLHDTKGPEIRTGKMRDGKKITLESGKSVVLTTDPAFELEGTADKFYVTYQQLAETVKVGDTVLLSDGLIRLTCTSVGKD-EITCHIHNTEEIGNRKGVNLPGLIVELPALSDKDKRDLDWGVEHDIDFIAASFIRKASDVNSIRSFVGECVKKPKIISKIENLEGIQNFEEILEASDGIMCARGDLGVEVPAQKVLTYQKMMVDRCNAVGKPVIVATQMLESMQNNPRPTRAEVSDVGNAVLDGADCVMLSGESAQGKYPIESVATMNTVIKEADQLLL-KPNYQAKFQFEPPTSDVESAVS-SAVKTANEMHAQLLIVLTRTGYTARKVAKYKPTVPVMCFTTDLKVGRQLQIHRGLYPVVPDYLDRAPTT-------AEAIAHAKKMGWLSAGDRVVVISGDKL............. 506
330 0.000e+00UniRef50_A0A1F5Z312 Pyruvate kinase n=1 Tax=Candidatus Glassbacteria bacterium RIFCSPLOWO2_12_FULL_58_11 TaxID=1817867 RepID=A0A1F5Z312_9BACT  ali  33  2.................LRKTKIICTLGPASWDRETVKRLLEAGMDAARINFSHGDRDSHLKIYQTLRESAESL-GRHLPIIGDLQGPRIRVGEIP-GKGLQLEKGSRVVLSSRNEPAAGS---RIGTTYPSLAGDLKPGVAVLLNDGLLRLTVEKIESG-DVHCRVEVGGLLTSHKGMNLPEVKVSVPALTGKDLEDLNFLLEQDFDYVALSFVQRSSDVLQAKEIIARAGSQMQVIAKIEKPSALDELEGILDESDGVIVARGDLGVELGVERVPAAQKKILRAAGKKSVLSITATQLLESMLVNPVPTRAEASDVANSVFDGSDALLFTGETAAGKYPVETVRTADRIVREAEGSMEAWGDRVMLRHQAAQ--NIPEAVCHAAADAARDLGAAAIVTGTQSGRTALLLSKFRPPMPVVGISDNVQAVRRMSLYSGVYPVQLPRM------EVLEESVEHAAAHLRESGTCKAGDSVVMTFGAPLGRGSTNTLRLVKI 471
331 0.000e+00UniRef50_A0A2E9MIT2 Pyruvate kinase n=3 Tax=Gemmatimonadetes TaxID=219685 RepID=A0A2E9MIT2_9BACT  ali  35  6..................RRAKIVCTIGPATQSESQLRELVEAGMDVARLNFSHGSHSDHAEVAGRLRRVSET-TGRSVALLQDLQGPKIRIGRLPGGA-LHLTDQQRIRLVIGESTDQEG---CIATPYEPLLGESRRSDPILLSDGLIRLEITDVSSDG-IDTVVVEGGILRERAGMNLPGAGTAVAALTAKDIDDLEFGLQLGVDYVALSFVRQSADVEDLRRRIAEQGSHAATIAKLEKPQAIEHLDDILNVADAVMIARGDLGVELSPERVPFVQKEIIRRAAERQVPVITATQMLESMVDHPRPTRAEASDVANAVLDGTDAVMLSAETAIGEHAVATVGMMHRIIVETETHASYLPGRGRRRRADDRESPFADAIAEAASGAASDARARAIVAFTQSGFTARLISKYRPSTPIIAFTPHEAIRRRMALFWGVEPRQIE------FVEEAEKMIATVDDALLSDGTTSTGDRLVFIAGTPTRQGTTNLLKLHR. 475
332 0.000e+00UniRef50_A0A2V8LLV8 Pyruvate kinase n=4 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V8LLV8_9BACT  ali  35  6.................LRRAKILATIGPASRDQETFEAMLAAGIDGVRINMSHGTIEEKTADVQMARTTAAKM-NRPLALLVDLSGPKIRTRTLRDHQKVELKTGQVFTITTR---QIEGDSTQVATNYPGMPNDVKPGDRILLDDGAIELQVESTGE-TDVVTRVINGGMLGERKGINLPGIKLPILSLTEKDREDLKWAAQQGVDYVALSFVRSAEDCEQAKELIKQAGSSAPLIAKIEKAEAIDHLEAIIAVADGVMVARGDLGVETSVELVPVYQKQIIEQANEAGKLVITATQMLQSMVDNPRPTRAEATDVANAVWDGSDCVMLSGETATGAYPVAAVATMARIIKTAETRRENQSIVSKLV--GRQSGRVSRALCEAAAFAADEMNTRIIAVFTESGLMARRLSSLRPDQRIIALTSSRQAINELSLIWGVDSVITTPSRS------TEELLKLGEQALLQNDLVDLGETIVIMAGRLSGLGLSSSVTLYKV 475
333 0.000e+00UniRef50_A0A1G1ACT9 Pyruvate kinase n=3 Tax=Bacteria TaxID=2 RepID=A0A1G1ACT9_9BACT  ali  33  7.............PKLHFRRTRIVATIGPASSSPEMLQAMIEAGVDIARINFSHGNPADHVKLMQRIHSSARKY-NRTVSILGDLCGPKIRVGDFHDGSAV-LKDGSKVIITSKAIL---GSPLLIPSQYERIVEDTRIGERILLDDGNLELRITRKIRN-SLEALVIHGGLLKNRKGMNLPDSKLKIQALTAKDRKDAAYCIRGNADFIALSFVRSAKDITDLKKHLKRMNSQIPVIAKIEKPEALDNIDEILDACDGIMIARGDLGVELPAEKVPIIQSSLIEKANRAYKPVIVATQMLESMIEHPRPTRAEVTDVSMACFADADAVMLSAESASGKFPILAVKTMDSILRETEAHQFFSSAGLFMNRTGFRRDDLLNALGSSTAQISRDLKVRCIAVLTRSGRTAKIVSADRPAAPVFAMTESEQVARRLNILWGVYPKIIPGKLSFR------KFVNYSERTIKDLHLAKKGDCIILLSGL-SGQGSTNSITIHR. 481
334 0.000e+00UniRef50_A0A136K2X7 Pyruvate kinase n=1 Tax=Chlorobi bacterium OLB4 TaxID=1617411 RepID=A0A136K2X7_9BACT  ali  37  4..................KKTKIICTIGPGVESVEKITGLIQSGMDAARLNFSHGDHEIHKRYIKNIRESSESC-GKIIPIIQDLSGPKIRVGKIVN-SEITLSEGQTITLTAEDI---TGNKDFLSLNHPEIIEDIKVGERVLMDDGNLMLKVVAKPNKHEVKCEVLTGGILKERKGVNLPDTELNVPSLTAKDIKDLDFGISNGLDLFAMSFVRSVDDIKMLKGILRAKGKSSPVISKIERPEAIANIDEIIKESDLVMVARGDLGVEISTEEVPLLQKMIIKKCNENLTPVITATQMLESMINSPTPTRAEASDVANAVLDGTDCVMLSAETSTGNYPIKAVEELKKIILRTETI--KKSSFFKEIFVEDSPENTLYTLCNSASVISLRLSAKAIITISQQGKSPLLLSSHRPAAQIINATFSPDLIKQSKLIWGVESILFDRKPDC----DLNNAFGQIREIIIRDGILNKGDRVVVLASIPFSEGSANSIMINRI 475
335 0.000e+00UniRef50_A0A0F6W9Z0 Pyruvate kinase n=5 Tax=Bacteria TaxID=2 RepID=A0A0F6W9Z0_9DELT  ali  36  1.................MRRAKIVCTLGPASSTPEMIDKLVAAGMDCARLNFSHGSHENHAKSAQMVREAAAR-AGRPLAILADLCGPKMRIGRFVEGK-ILLEPGQRFTLTTRDV---PGTKDIVNQIYEPLPRDVGPGTHILLDDGLLRLRVIETT-DTDVVTEVEIGGELSDRKGLNVPGAALSTPAVTDKDRKDLEFAVELKVDYVALSFVRRAEDVLDAKAL----ARGTPLIAKIEKPEAMENLEAILDVSDGAMVARGDLGVEVGAEFVPLMQKRIIREVNKRGKVVITATQMLDSMIRNPRPTRAEAADVANAVLDGTDAVMLSGESASGKYPVESVQMMDAIVREVERSLKELRTATDLAPLSDEKWTFTEAAARAAARLTYIMPLEAIVVFTRDGRTARVLSENRPRSPVIAVTSRPEVATRLALEWGVFPRV------EIPPDDLEETLRIATSLLVREKMCKQGGEFALVTGWPL-SGGTNTIKLHR. 467
336 0.000e+00UniRef50_D8K0X1 Pyruvate kinase n=20 Tax=Chloroflexi TaxID=200795 RepID=D8K0X1_DEHLB  ali  37  13..................RRTKIVATIGPASAEPETLDEIIKAGMNVARFNLSHGTXXX-XXXXXXXXXXXXXXXXXXVAVLIDLPGPKYRTGTVAAG-SVRLVNGGTIILTTREV---PGSEREVSVNLPALPRDVRPGDTILVDDGAIQLKCREI-KGPDVFCTIVVGGTLTQGRGIAIPGRKSSMPFLSDALKRYLEFAVAQRPDYIALSFVSRAADVSQVRKILGKKGSDIPLIAKIERGAAVKAFDAVLEEVDGIMVARGDLGVDIPLEKLPLVQKEIIRKSNRAGKPVITATQMLESMISSARPTRAEVTDVANAILDGSDAVMLSAETSVGKYPVQAVKMMAAVAMETEKTLPYDLWIAE--RDSWLTDQTEELISYNAILTARRLGAAAIVAFTSSGSTAGRVAKYRPSAPILAISPNGDICRRLILNWGVQASQIPTPRT------VDDLFVTAVKLVKKLRLAEAGDKIIVTGGVPIGAGTTNLLKVQEV 481
337 0.000e+00UniRef50_A0A2H0VD80 Pyruvate kinase n=3 Tax=Bacteria candidate phyla TaxID=1783234 RepID=A0A2H0VD80_9BACT  ali  36  1.................MKKTKIVCTIGPASDSYEVLLNMARAGMDVVRLNLSHGDYSSHKKIIGHVRKIGKEL-NRPIGIMLDLQGPKIRIGELA--KPIVLKKGTAVILTHKVNEVGHTDHQVLPIQ-VDLRSSLKPEDLILIDDGKIHLKVLRV-KGLRVWARVESGGVLSTHKGINLPNSVVKIPLVSKKDEEDLKFGLENDVDFVALSFVQHPRDLLHLQKLVKKHNRDPWIISKIEKASAVKEFEKILQFSGGAMVARGDLGVEIPAQEVPIVQKEIIELCLRNSKPSVVATQMLDSMVKSPTPTRAEVTDVANAVTDHADAVMLSQETAVGEYPVKAVELMSKIISETEASIYDDLPHDYLKD---EKNSRALAVADSAHELSKNTGAKAIVGATVSGFTARMISHQRPNAEIIMMTQDEKVYRQMSLLWGVRAFMISRCRT------LEEIIQKSVTLAKRRKLVKKGDKIVIVTGQPVGQRNMNLVEVQTV 475
338 0.000e+00UniRef50_U1FPK9 Pyruvate kinase n=17 Tax=Bacteria TaxID=2 RepID=U1FPK9_TRESO  ali  38  3.................LRKTKIVCSIGPASNNDDIAAKMIRAGMDIARFNFSHGTHESQKDMMERIRRLSREI-GKPVALMMDSKGPEIRTGIVPDNKTITVNKGERVIVTADDSPVTAANGKHISLSWRDLPKRIQSGHKILIADGLLELDV-ESSDGTKVVCTAANTATIGSKKNVNLIGLHAGLPIMSEQDKADIAFSVRMNCDFIAASFTSFASEVHEIRRYIESLGSNMKIIAKIENEEGLDNIAEIAQAADGVMVARGDMGVQLPIERIPLAQKRIIEECRRAGKPVITATQMLDSMIVNPRPTRAELTDVANAIFDGTDAVMLSGETANGAYPAEAVETMARIAQTVEDSEEYCSRIKAAPPIPEGDVTIGRIMAQMAYETADKTKALVIIVPTMSGNTARMISTFRPEQAILAVTPNEQVQRQMLIDWGVFPLV------SKTADDSEDMVQNAVKIALDNGFVRQSDRIILCAGIPLVSPPVNTIRVLLV 481
339 0.000e+00UniRef50_A0A2E6ENS7 Pyruvate kinase n=2 Tax=Proteobacteria TaxID=1224 RepID=A0A2E6ENS7_9RICK  ali  35  14..............PLPVRNTKIIATLGPASSSPEMLGRLMKAGMDVARLNCSHASHGDLAIQVENIRRVA-RLSKKAVAILLDLSGPKVRSGKLIGET-MELVKGAKLRILPGN---EPGRDDWITCNHPGLAKDVEEGDRILLDDGLMELQVRSV--GDEIITEVITGGILKQRKGMNLPDNVVSLPALTAKDREDLKVGLELGVDYVALSFVQSATDIRDLQAAMKELRGRAPIIAKIEKPQAVESLDEILAEVAGIMVARGDLAVEVGNHRVPVMQKEILRKSNLCGTLDIVATQMLESMTNNPRPTRAEASDVANAVIDGCDALMLSGETATGKYPVEAVAVMDRIAKEVEPYMS-ETAQPPLQPSASREQAITMAVVQAAAQVATISKCAALMVFTLSGRTARLLGGFYPKSRIIALTPNKDTYRAMALYRGVEPVYM------QFPANSDHMLLQGERLLVEMGLLEKGDEVVVVAGFTELKGVANMVKVVRI 485
340 0.000e+00UniRef50_A0A2H6B5Y7 Pyruvate kinase n=7 Tax=Bacteria TaxID=2 RepID=A0A2H6B5Y7_9BACT  ali  35  1.................MRATKIVATIGPASSDERVLERMIRAGMDIARINFAHGEPEDH-ERMARAVRAAAARVGREVALLGDLPGPKLRVGPVAGGVA-ELPRGGTVVLTPNPVL---GTSERLSVDWPGLAEVLEPGDVCYLADGTVRLRVRDVRDG-DVVAHVEVGGPVASRQGLNLPNVTTALPALSDDDLRLLAHAVELGFDALAVSFVRRREDVEQVRRELGERGSDIPLIAKIEKPQAARNAEEIIEAADAIMIARGDLGIELPIEEVPLVQKRLLALAGKKAKPSITATQMLESMVHSTRPTRAEVADVANAIFDGTDAVMLSEETAVGMHPAEAVAMMAAIAEATEPELPYGRW---LTERGPRAADQYHAIAFGAVGAAYQLGLRAIVTPTQTGATARLISAYRPQVPVLALAPRIEVVRRCNFLWGVHPRLHDEPRE------TIDLIESSARAALEAGFARPGELVGITAGLPPGAGGTNLFKIHR. 468
341 0.000e+00UniRef50_A0A1Z2TMA9 Pyruvate kinase n=6 Tax=Euryarchaeota TaxID=28890 RepID=A0A1Z2TMA9_9EURY  ali  36  7...................KTKIVATIGPASMNRKTIEAMIRAGLSVARINFAHGDLEQHAKTIETVREASERL-NRPVAILGDLPGVKIRVGEILNG-SVTLRRWQTVVLTTRDVV---GTEGEIPVEFKEFPKMVSKGDVIYLSDGFIALRVEDVR-GPDVICKVLVGGTLFSYKGINVPKARMAIDAVTDRDLEFIEFAIEHGIDAVGISFVGSAYDVLKVRRFVEERKGSLFIIAKIERPDAVKNFDDILCAADGIMIARGDLGVEMPIEKLPVLQKKLIHKANVAGKPVITATQMLESMTEEKLPTRAEVTDVANAILDGTDAVMLSEETAVGKYPVDAVRMMARIAKTIEAYRDSQWSMTRWSEKGPKKGTIKDTIARSIIEALNSMDIKYILTPTRTGETARLISRFKPKQWVLAFATDEHVARSLMFSYGVYPFVVTETSE-----------EEILRLIRGLGLVKENDPVLLTKGTPIGKTGTNTIRIFTV 478
342 0.000e+00UniRef50_A0A1B6G1K6 Pyruvate kinase (Fragment) n=3 Tax=Neoptera TaxID=33340 RepID=A0A1B6G1K6_9HEMI  ali  50  75.TKLEHICGLDIDSKCYFRLSGIVCTIGPASTDPSMLEKMIHKGMNVARLNFSHGSHEYHANTIKNVRLAVKSYSGKPLGIALDTKGPEIRTGLLEGGGSVELKKGNTIRLRTDKSFEEKGTGNDIFVDYVNITKVVKPGDKIFVDDGLISLIVNKIDKDQ-LTCTIENGGMLGSKKGINLPGVPVDLPAITERDRRDLKFGVEQGIDIIFASFIRDASAIVEIRKILGEEGKKIKIIAKIENHQGCVNLDEIIDAADGIMVARGDLGIEIPPEKVFLAQKTMIARCNLKGKPVICATQMLESMIKKPRPTRAEVSDVANAILDGADCVMLSGETAKGDYPLECVEVMANICREAEAAIWHRELFEGLTSKIGRP............................................................................................................................. 455
343 0.000e+00UniRef50_A0A2G6H8N2 Pyruvate kinase n=3 Tax=unclassified Bacteroidetes (miscellaneous) TaxID=37452 RepID=A0A2G6H8N2_9BACT  ali  37  3..................KRTKIIATIGPAIKDLKTLTEIIEAGVNIVRFNFSHGSYEEHQERVNLVHKANEQL-GSNVAILADLQGPKIRTGIVPDNG-ITLEKGDRIVFTNQPLI---GTKEKISVQYHDFPNDVKLGDMIMIDDGKLLFKVLSTDGEKEVLLEAQVKGVIKSRKGINLPNTQISLPGLTEKDKKDLEFILSLNVHWVALSFVRSASDIEVLRELIQAHPNPVKIIAKIEKPEALEEIDKIIAVSDGIMVARGDLGIEVPQEKVPMIQKELVKKCLALAKPIIIATQMMEGMICNVRPTRAEVSDVANSVLDGADALMLSGETSVGDYPVEVVQTMHQIITEAEGE-GYPYYRPYTLSKPEDERFISDAILTQSCTLAQQCKAASINTLTNSGYSAFKLSSLRPNTRLFIFTNRPHLVETLSLVWGVEAFFLEPQGS------TSKTIKAMITLLRKHHSLEKGDVIINLASGPVYEGTTNMLRLGVI 475
344 0.000e+00UniRef50_L0JWJ5 Pyruvate kinase n=227 Tax=Archaea TaxID=2157 RepID=L0JWJ5_9EURY  ali  35  1.................MRNAKIVCTLGPASDDRGTIASLADAGMSVARLNASHGSLEDRATLIDRVR-AVDEQSDDPVAVMLDMKGPEVRTAPLPDDETVTLETGSEIEFVEGEDA----SPDRVGLSLP--IEEVEAGDRILLDDGLIETTVLERSAG-VVRARVDTGGELGGRKGVNVPGVDLDLDIVTDSDRKDLELGAEKEVDFVAASFVRDAEDVYEVSEVLEELGADVPIISKIERAGAVENLDEIIDASYGIMVARGDLGVECPMEDVPMIQKRIIRKCHEAGSPVITATEMLDSMVHARRPTRAEASDVANAVLDGTDGVMLSAETAIGDHPTEVVDAMDSIVREVENSEEYAETLEQRVPTAGEAR--TDALARSARYMARDVGADAIVAATESGYTALKTAKYRPGVPVVASTPNDDVRRRLALSWGVTPLYARVSDQGA-----DAVVEKAVQAALDAGVADSGDTVVVLCGMMTGANTTNMMKVHV. 471
345 0.000e+00UniRef50_A0A1F7UNU1 Pyruvate kinase n=1 Tax=Candidatus Uhrbacteria bacterium RIFCSPHIGHO2_12_FULL_60_25 TaxID=1802399 RepID=A0A1F7UNU1_9BACT  ali  40  1.................MKRTKIVCTIGPACDTVATMVALGKAGMNVARLNFSHGTYASHASLLTRLRKAERSL-DQPFGILQDLQGPKIRVGDLPKEG-VKLVDGKPVVFTTSARPVRG----DITVSLPGLHHDVKRGERLLLDDGLLECVVRRI-EGRRIHCEVIHGGTLTSHKGLNLPGTKLRIPALSKKDLADAAWGVAAGVDFIALSFIRSPNDVLDLRRILNKDGKHIMVVGKIEKQEAIDRFDDILPLLDVVMVARGDLGIETPAPKVPVIQKQLIAASRSAGKPVIVATQMLDSMQRNPRPTRAEVSDVANAVADHADAVMLSGETATGQYPVDAVRMMAETARATEASPFDDLA----SFNVSAERDIPELIGGSVRVASDALDHAPIVVLTSSGRTAREVSAYRPEATIHAVTNDVRVARQLQVSWGVRATVTSTTSRP------DQRAKRAVSLLQRAKRLPRGQRVIVVGGTPGKSGTANRIEVVTV 469
346 0.000e+00UniRef50_A0A2A4MJE3 Pyruvate kinase n=2 Tax=Candidatus Marinimicrobia bacterium TaxID=2026760 RepID=A0A2A4MJE3_9BACT  ali  32  1.................MRKTKIIATLGPATNSREKIDQLIHAGLDVARINLSHASPSHLRKTVQLIREQSTKFE-KSIAILFDLGGPKIRVGKINKAEAIQINDGDEYSL--------GGDSCDIPINMELSFSDHTRGGEIKIDDGSISFDIVAVQENH-LQIRAKNSGEITSGKGINFPGVKLNLPSVTEKDFTDIQLAIDLKXDWIAMSFVRSADDLXLIXNELEKRNVKIPVIAKIEKPEAIENLNDIINAFDGILVARGDLGVEMPLKELPILQKKIVNQCLQNRKPVIIATQMLDTMIHNPTPTRAEVNDIANAIYDGADAVMLSGETAVGEYPVESVQIMADIAQSVEKDLDRQNFNRYILNESMHYLDSRGSICHAAMTISNDLFINTIVIMTESGVTAMKMAQHRPRARIFALSPDSNVCHQLALIWGITPLLV------NSVTSTDKMIIDSSELLKERKFIKKGDSFIITAGVPVGVGSTNMLKIHSV 469
347 0.000e+00UniRef50_A0A1Z8Q3J1 Pyruvate kinase n=1 Tax=Micavibrio sp. TMED27 TaxID=1986607 RepID=A0A1Z8Q3J1_9PROT  ali  33  9..................RQTKILATLGPSSNTEETIEQLFLAGVNIFRLNFSHGDHKTHQKTAQIIRNIEQKH-NRPIGILADLQGPKLRIGTFKDG-SVEMVRGDMLKFDSNP---EPGDKSRIYMPHPEIFSALKKDGLFFIDDGKVRCRVRELGQDEYFIAEIRAGGKLSDKKGFNVPESYLEIPALTDKDKIDLKAALEIGADWIAQSFVQTGADVAEAKALI---NGKAKLIVKLEKPAALENLEEIVALADGVMLARGDLGVEIPPENVPSVQKHVVRYVRGLGKPIVVATQMLESMITSSRPTRAEASDVATAVYDGADAVMLSAETAAGEHPIRSVXMMNKICRRTETDEIYDEFMEEAQPDTIG--DPSDAIATAANYVAQDIEAKAIVSYTASGATALRMARQRPKVPILCLTPNLSVARALSLSYGIHTVHAPQISGEFSG-----AVPFACKILVSENLAXKGXRFVMSAGVPFGVGSTNLLRIAEV 479
348 0.000e+00UniRef50_A0A1Y4N760 Pyruvate kinase n=4 Tax=Clostridiales TaxID=186802 RepID=A0A1Y4N760_9FIRM  ali  37  6.................MRKTKIVCTMGPACDDKETLKKMIAAGMDVARFNMSHGTYEEQKKRFNTVKTAIAE-SGKNVAILLDTKGPEVRVGIFENG-FVELQEGQEFSL---LKEGDKGNDKGVPLSYPKLVELFAKGREILLDDGKLSFVVKEANQD-AIVCTVVKGGRLSNRKSINIPNYHINMPYVSAKDRADIEFGLEQGANVIAASFVRSADDVIKLRDYIDSIGFEVEIIAKIENQSGVDDIDRILEVADGIMVARGDMGVEIPFIKLPEIQKTLIRKTVVAGKYVITATQMLESMTNSPRPTRAEISDVANAVYDGTSAVMLSGESAAGKYPVESVQALNDICCEAESN-GESIALQEYIKKYPITESFRETICHAAKDVAENINAKAIIVESATGQVARAMAHYRPSCPIIAVVTSERVCKKLCLNWGITAVIGEEKLT------TDAITKQAMVKALSTGYVKKGDTVLVLSSNKTVPTSTDTLNIRII 482
349 0.000e+00UniRef50_Q9VQH0 Pyruvate kinase n=31 Tax=Drosophila TaxID=2081351 RepID=Q9VQH0_DROME  ali  37  14.TQLSHICELDLQQASHQRLVSLIATISVSSRNADTIYTMIMRGVNIFRLNFSHESHEMHSKTIELINEALERIHKRTVAIAADTRGPQIRTGLLDGD--VFLRSGDNLRLSINRDLYDKGNKEAVYVDYPNIINLTKTGDRLFIDDGRLLLHILEVGVDG-LLCEVIHGGQLNNNCNVILPEIEIDLPAVSEKDMFDIQFSIKANVDFLFASAVRSAKNVKELRTVLGEKGKHIKIIAKMDSKIALSRFSEILRAADGLLLSRADLGTQIPIEKLFITQKSILGQCNKVGKPVIVASHILESMRTLPHPTRAECFDLANAIIDGADCIMLSSEVAIGSFPKETVATCDTLCREAEKVLWFRDLFSDLVSEVRGELDAAHSLAIAAVETAKRTNATLIIVLTTSGRSATLVSKFRPRCPIMAITRCERTARWVYLHRGVLPILYTLEPSTDYATDVDARVQFAMTSAKKWGIIDDGDPIVIVSAWKDGGGFTNNVRVV.. 513
350 0.000e+00UniRef50_A0A109CUK0 Pyruvate kinase n=1 Tax=Nitrospirae bacterium HCH-1 TaxID=1748249 RepID=A0A109CUK0_9BACT  ali  37  1.................MTYTKIVATLGPETSNDKSVEELIKAGVDVFRLNFSHGAHAEHKERIDLIRRVSRKI-GIEVALLQDLCGPKIRTGKMQPGG-VLLAEGAKVSIVTENVI---GTEERFSCIYELLTRDVHPGEKILLDDGSMELRVDSV-DKALVLCTVIRGGLLKSSKGMNLPGSKISSPALTDKDRDDLEFGLREKVDFVALSFVRDANDIRQLRNIVGA--KDIRIIAKIEKPEAIAHIDEIIHEADGVMVARGDLGVEMDLAEVPLLQKQIIHKANAADRYVITATQMLESMIESPFPTRAEVTDVANAVIDGTDAVMLSGETAVGKYPIVTVKTMKHIARTTEKYLKQHPPKWNWVHIN-TSTEVHNAISRAVLQFSRDLAVKAICAYSPSGGTSVYLSKSRPFAPIIIFTPSIEAVRRMHLYWGVIPVL------DTTIKSKEELERKANEFVQEREFAIQGDTILLIHGSVFGVGKNSIIEIKTV 469
351 0.000e+00UniRef50_UPI0006986DE4 pyruvate kinase n=1 Tax=Nitriliruptor alkaliphilus TaxID=427918 RepID=UPI0006986DE4  ali  37  1.................MRRAKIVATLGPALDDPDRLRAAIAAGIDVVRLNFSHGSREEHQRRLELSREIGASL-GRNVGSLGDLQGPKIRLG-LVPDAGVQLVDGGEVVLVAGEEELERYDDPVLPVVYAELADDVDPGALILLDDGLLRLVVSRV-EGKRVTARVVAGGLAKSRKGVNLPGVEVSAKSLTDKDLVDVRTMVELGVDWIALSFVRRPEDVHEVRAMVKELGGQQPIIAKLERPEAIDDLEAIIAATDAVMVARGDLGVEVGPERVPAIQKQIIDLSNRAGRPVITATEMLDSMIRSPRPTRAEASDVANAIFDGTDAVMLSGETAAGRFPVEAVRTMARIIEVAESSAERVHPVPPITGQELQR-----VVCKAAVQIAQDVDAKAILVYSLTGASAQLVSKFRPAYPVIGLTPDERPLRRFALMWGTAGAVVPTKDHSI------DLITAAEEVCFEHGYAAHGDAIVIVSGIPGGHGGTNRVMVHR. 472
352 0.000e+00UniRef50_A0A2N2CEF9 Pyruvate kinase n=2 Tax=unclassified Firmicutes sensu stricto (miscellaneous) TaxID=84086 RepID=A0A2N2CEF9_9FIRM  ali  36  9.........LERNKENTMRKTKIICTMGPATE--GIYEDMILNGMDAARFNFSHENHEVHGHRIKTMKAARTKL-NQPIPLIVDTKGPEMRIGVLKN--KVNLINGETIRLISEEI---EGDEKAVTISFKDLYKSVTIGQSIYIDDGRINLEVVSI-EGTDIVCKIIAGGVLSSRKGVNVPGCITGLPFMTEKDRADIEFAVDQDVDFIALSFVSNAKDVESVREIFKQKNRDIKIISKIENTEAIKNIDEIIAVSDSIMIARGDLGIELPVKSVPIIQKKLIKKCYTSSKPVIVATQMLESMTDNPVPTRAEVSDVANAIYDGTSVVMLSGETAAGKYPVETLRMMTTVILETENDIDYKVKLDEGAWKV-IDQNVINAISEVTVIAASKIDAKAIVVPTRSGNSVRMISSFRPACPIIAITLEEGLQRQLNLSWGIRPMM------SKFIGDQKEFFEKVLDQAVATNLVENGDLIILTAGIPTGDGKTNMLKMHKV 485
353 0.000e+00UniRef50_A0A2D7PJZ9 Pyruvate kinase n=2 Tax=Bacteria TaxID=2 RepID=A0A2D7PJZ9_9DELT  ali  37  76.................LRKTKIIATIGPACDEPRTLASMIEAGMNVARINLSHGTFDEQRARIERVRSAAQQ-KEANLAILIDTRGFEIRTGPVEGGGAV-LVAGQPFALHCTP---TAGDEHGVSVSFNGIAEILKVGDRVVIDDGKIELVVSALRQGR-VDCEVTCGGTLRDRKGVNLPDTQLIRDDLDEGSHADLDFAAEIAADYVAASFVQTGKDVDEIRRHLESRQTTIPIIAKIENGLGVQNLETIIERANGAMVARGDLGVELPVTQLPHIQKHIIRTTVSRGKPVITATQMLDSMERNPRPTRAEVSDVANAILDGSSAIMLSGETAAGLHPVEAVSTMAELALSAEASLEEYGTLQNVVGNPSDA--IVEAVAQAAITMAKHIDAAAIIALTDTGFTARSISKFRPHCPIFAVTGSESVRRRLAMNWGVTPILYPGHG------DDDESIEFAVRYGSERGHLRPRDVIVATAGRSQMSGGTDMIQVRRV 544
354 0.000e+00UniRef50_A0A2E9A2K5 Pyruvate kinase n=9 Tax=Alphaproteobacteria TaxID=28211 RepID=A0A2E9A2K5_9RICK  ali  33  5..................RKAKILATLGPSSSSPEIMEEMFVNGCDVFRLNFSHDTIENHRKNLENIRNLEKKY-NHSTCVLADLQGPKLRVGYFKNKEE-NLKKGQIIRLDLNN---EKGDKERINFPHPEIYEFLTPNTILLVDDGKIKLQIIEQNKD-FLKAEILNDGTISDNKGINIPDVILPIESLTNKDKSDLKKALEMGVDWVALSFVQQPEDILKLKKIIDNK---ALIMAKIEKPSAVKNIDEIIKVSDGIMIARGDLGVEMQTEKVPIVQKNIIKRCRYFGKPVVVATQMLESMVNNLVPTRAEASDVANAIYDGTDAVMLSGESAVGKHPIETVKVMNNIIENVEMDKNNFDL-DSNNNESKTKTDNTDAITNAAYSIAKNAGAKAIITFSVSGKTTMRMAKERAPVQIIGLSPYLKTSRKMQLVWGVNSCHSDDAQSAT------EMVRIACVIAKDKGLVKPDDNVIITAGIPFGAGSTNLLRIAKI 471
355 0.000e+00UniRef50_A0A136JLA5 Pyruvate kinase n=1 Tax=Parcubacteria bacterium OLB19 TaxID=1617425 RepID=A0A136JLA5_9BACT  ali  36  8...................KTKIVATLGPNSNSVAMIEKMLMEGLSVARINMSHGDHSTHAESIKNAR-LASKRTKRPLAILQDLSGPKIRIGDFETE-DVTLVNGNTLVLTTESCV---GTSERVHVNYPKLPKEVEVGMYIYLNDGKQKLLVDSVT-DSEITTTIISGGIIRGRRGVNIPDANLSISSLTAKDKKDLVFGLEQGVDFVTLSFVRDADDIRQLRKLTEKKGK-VNIVAKIETKFAIDNLEEIVEVSDVIMVARGDLAIEMPLEKVPLLQKHIIHTANKAGKPVITATQMLDSMRIATTPTRAEVTDIANAILDGTDAVMLSDETAVGVHPDRVIHIMSKVAYEVENDVFFARHQAD---WDFSPNSVYEAVGRSVVKTAGAVSTKAIVAFTESGYTSRMVARYRPQVPIFVLTPRKETFSHALIVYGCEPVLIKK------VKNLAEAQKTARKVVLDSGLVDKGDLYVLTAGVPFGSGATNMMIVEKV 473
356 0.000e+00UniRef50_A0A1V5PUL6 Pyruvate kinase n=1 Tax=Actinobacteria bacterium ADurb.Bin346 TaxID=1852788 RepID=A0A1V5PUL6_9ACTN  ali  36  1.................MRKTRIICTIGPSSADPAILEKLMLNGMDIARINTSHSSMEDALAKINLIRDIAKRNK-IDTGILLDLQGPKIRIGKLDDD--IFLEDNQDIIFTTERKGAGSSTSSRINVEYKYFLDDIRQGCSIFIDDGLIELKVVSIDKKRRLQAKVIRGGVLKSKKGINLPGITVSVNSVTEKDLEFLNFGITNNVDFIAQSFVRSSEDIKQIKDIVKKHKSHMMVIAKIEKHEAIADFENILRHSDAIMIARGDLGIEISEEDVPNIQKEIIRKSNITGKPVITATQMLDSMIRNPRPTRAEVSDVANAIFDGSDALMLSGETASGAYPLQALQMMVRIINRTEESLDYTEIMK--KKFSQKQHSITEAISFAACEIANVLGATAIITATRSGSTARHISKNRPACMIIGASSNDYVIRQLMLSWGVIPVRTK------FTKNVSSMLNEAVQVSKNAGYIKDGEKVIITGGILSRPGSTNFINVREI 502
357 0.000e+00UniRef50_A0A1L6MZ89 Pyruvate kinase n=2 Tax=Pajaroellobacter abortibovis TaxID=1882918 RepID=A0A1L6MZ89_9DELT  ali  33  2.................VRRSKLVCTLGPACNSVEAIKGLIEAGMDVARLNFSHGTQAEHLKHINYLREASRQ-SGKWIPALQDLCGPKMRTGQIP--ERYELKVGTHVTLIEGN---ESSDPSVIPIPYEGLANDVRPFDTILFDDGRIVAKIAEIKEDR-ILASIVQGGTMRSYVGVHLPSRTMRVSALTEKDRDDLHFGLEQGVDFVALSFVRRDSDIKFVRQLCAEWNQPTPIIAKIETPDAVENLESIMIATDGVMVARGDLGVEFPPEQVPIIQKKILNTAKRVQRPVIVATEMLQSMTAATRPTRAEASDVANAIFSGTDALMLSGETATGAHPALVTMMMSRIATAAETSLFLEEPPYSIQMVPPQSTTVAEAIARGACKTAQEIGAKFLVAFTETGSSAIKVSLARPYIPIIAFSPNPRTRRQMGLYWGVIP------REAPPLHDMDALICWCTDDLLNFGFASPNDKVVMVFGAPFGSGSTNSIRVH.. 471
358 0.000e+00UniRef50_A0A2M8T8H6 Pyruvate kinase n=82 Tax=Bacteria TaxID=2 RepID=A0A2M8T8H6_9CLOT  ali  41  1.................MQKTKMIFTIGPSSDTEEKLRELINVGMNAARLNFSHGTHESHKEKMDIIRKLRKEL-NKNVAIVVDIKGPKIRTHNFENDKA-EIKKGQKFTIICGEEIL--GNSEKCSVSYENLYNDVKKGGLLLVDDGLLEFRIDDIV-DKSIICSAINSGVISNHKGVNAPGVSISLPAVTEKDVLDLKFACETKADLVAASFIRKPEDVTVVRNILNENGKNIKVIPKIETQEGVDNIDKIIELSDGIMVARGDMGVEIPIEDVPGIQKMIIKKCNDAGKIVITATQMLDSMIRNPRPTRAEASDVANAIYDGTDAIMLSGESASGLYPIEAAETMSKIAQKTESQIDYTKALNERKDEAITK--ISDAISLAACSTAAELKAAAIITATQSGITARMVSKFRPTCPIIAVTPHDWVARSLALNFGITPI------TSKQVLSTDELISESITRALSEGLIKKGDLVVVAGVPVGKSGTTNMLKL... 469
359 0.000e+00UniRef50_A0A136NVD2 Pyruvate kinase n=2 Tax=unclassified Chloroflexi (miscellaneous) TaxID=189774 RepID=A0A136NVD2_9CHLR  ali  36  9..................KKTKIVATIGPKSSDEETLRQMIRAGMNVARINFSHGAQDEHAARIERVRRIAAE-EDTVVAILSDIQGPKIRIGQV-KDTGIPLHAGDKVVLTLDEKAD--GTNNIIPLPHPEFITDVLAGMTLLLDDGNLEFKVDSNNS-KELHCTVVIGGNLTSRKGVMAREAKHKMRAITDKDRKDVEFALEQGTDFIAMSFVRSADDVQEMRWLMRHLGHDVGLIAKIEKHEALDRMESILAGVDGIMVARGDLGLEIGAENVPYHQKRIISLCNKVNKPVITATQMLSSMEHSPRPTRAEASDVYNAIVDGTDAVMLSNETATGEYPVEAVRMMAHIARNAETHLPAGRTQDD--KHLEGVERIADAICESTFQVSEALKAKAIVTASLTGFTAQRVAGERPTTPIFCVTPRQSTYRRMALVWGVIPLLVDQFQT------IEEMIRVVALQAQAAGIAAQGDIVVIVAGVPFGGGGTNLLKVHRI 479
360 0.000e+00UniRef50_UPI000644DE8E hypothetical protein n=1 Tax=Acytostelium subglobosum LB1 TaxID=1410327 RepID=UPI000644DE8E  ali  39  1.................MIRTKIICTMGPAVSSYDKILELIDAGMNVARINFSHGTHEEHLRVIQNLKKARAA-KNVPLAIMADTKGPEIRLGSIKNE-SIRLTSGQRILLS---KKQVEGDETAVSLTPPEVVDAIEVGMKLLFDDGYIVAKAVEKKEEGVVI-EIQNADLLKSHKSVSIPKAHIDLPAMTEQDLVDLAFVCKNDLDLIAASFVRSADHILEIKHYLESQEKDILVIAKIENSLGVNNFDAILQVADGIMVARGDLGIELPLEEVPRLQKMMIRKCCEASKPVVTATQMLESMIKHPRPTRAEVSDVANAIYDSSSAVMLSGETAVGSYPVEAVKMMKRIVQTAENDFSFREFFSH---QNWGSDNVSKSVSRASVQTAYTADAKAIFTVTTSGSTACLISRFRPQMPIFALTPHETVYHQMAFLWGVIPL------KTNPLKNVQEAITLGADYGKRAAMLQSGDIIVVTTGSPFIKGTTNTMIVETI 470
361 0.000e+00UniRef50_A0A257BH35 Pyruvate kinase n=4 Tax=Bacteria TaxID=2 RepID=A0A257BH35_9BACT  ali  36  1.................MRRTKIIATLGPAIETQEKLYDLVEAGANLFRINAAHGDWHTRRQWIEWIRNAEQTYK-IPLGVLLDLAGPKIRIGNLR--APMELAPQQRVEFQLGEQQ----TDSSIPLPVAEVFRAARAGDRLLLDDGAIELQITRVGSDH-LEATVLEGGELRSQKGVTLPHRTLALPSMTPKDREDLLEGIRAGVDWIALSFVRSVTDIMNLQALIREQGASTPVIAKIEQPAALDDLESIVEVADGIMVARGDLGVQVDLAEVPILQKQIIHLCNQHAKPVITATQMLESMIHEGRPTRAEATDVANAVLDGTDALMLSGETAVGAFPTQAVRWMARIAEVAEEHLEFLQLGE---LDAHTAGNATVAVARAACTVAQMVGAKAILTPTSSGGTTRWVSHFRPYQPILALTDNEPLWRRLTLLWGVAPLLIPRVNT------TDEMTTQAMIAARQTRLVKGGDRVVLTAGVPVNPGNTNMIQVLT. 466
362 0.000e+00UniRef50_H0A959 Pyruvate kinase n=5 Tax=root TaxID=1 RepID=H0A959_HALSG  ali  39  1.................MKNTKIVSTIGPSTNSKKELDAIIDSGVDVIRQNFSHVDHSTHGQIFDRVRETSEK-----TAVMIDTKGPEIRLGQVKEGT--VLETGHNVELTTEEV---EGNEEVLSVNYIDFIDHIEAGDEVRIDDGKIELEVEKV--GDTAECTVVYGGEVSSRKAVNVPGKDIGLQAPTEKDVEDIEFAAEKGYDFVSLSFVKQASDVEEVREILEEHDSEMHIISKIEHKKAVENFDEILEASDAIMVARGDLGVEIPAAELPMMQKEMIEKCNEAGKPVITATQMLESMTENPTATRAEISDVANAVLDGSDAVMLSGETAIGEYPVKTVKFMASVVEEAEASMEGKTHH----TVKQPPETTREIICKNVWQASRDSEAEYIVAHTSSGSTARNISKYRPENPIITFTDSEIVERQLQLSWGVRAYY------EEFPSDVEGMLEASAKRMENLNLASGDDELVLSAGIPTSVGTTNMMQIRTV 462
363 0.000e+00UniRef50_A0A0L1KPY9 Pyruvate kinase n=1 Tax=Perkinsela sp. CCAP 1560/4 TaxID=1314962 RepID=A0A0L1KPY9_9EUGL  ali  42  4VSLLQGNSSLKYDAGPPRRATKIICTIGPSTQSVESLKTLIGNGMNVVRMNFSHGTHAYHEKTVENAKQAAQEL-DANLSIALDTKGPEIRTGLFPEGE-IKLSYGQELYVTTDKSWKDCGSSECFYIDYSHLPSLMKPGDRIYIDDGLLGLDVVSV-EGDRLRVRVAIPSAISSNKGCNLPDKPVELPAVSQKDREDLLWARKFGVDMIFASFIRCADQVEEVRDIV---GPGIMIISKIENQQGLDNIDEIIEKSDGVMIARGDLGVEIPPESLLLAQKMIIAKCNIAGKPVICATQMLDSMTNNPRPTRAEISDVGNAVLDGVDCVMLSGETAKGQFPNATVDVMSRICANTQKAMVYQRRTQEIIDAQGDAFYKEDAFARAVVRTAFENAVQGIVILCHSTVMVQNVSKYHPSCPIFAITYDEKVCRKLSIVRSAEPLLHCEM--DFYADPSIERVRVIL--GKKAHFLKEGNPLLLV.................. 477
364 0.000e+00UniRef50_A0A2E0N6N8 Pyruvate kinase n=18 Tax=Bacteria TaxID=2 RepID=A0A2E0N6N8_9GAMM  ali  38  10..................RKTKIIATVGPACDDVATLEDMIHAGLNVVRLNLSHGDYESHANRVAQVRQAASNVR-AHVAIMVDTKGIEVRTGLLEDG-PVFLEADQTFTLFADD---RKGNLAGVSVSYRKLSAGVKKGDVILLDDGAIELSVAAVNAA-AIECVVVHGGMLGERKGVNLPGAQLAISAISPEFLENLEFAVAQQVDYMAASFVQSGSEIQGIRDRLNARGSNIPIIAKIENQAGVDNVEAIVAAADGIMVARGDLGVELPLAEVPSTQKKLIQCSVTNGKPAVTATQMLASMETNPKPTRAEASDVANAILDGTSAVMLSGETAVGQYPVVAIQTMSAIALRAEASLREFGFLQTIRMTEAAK--IAEAIGQAAARLAEQLQAAAIITLTDSGYTARLISRHRPESLILAVTASDRVARRLAMNWGVIPLLYDEEN----ADSDESRTRFGCGRARELGLLETGDVVVITHGTQQGAGGTDLIRVLEI 483
365 0.000e+00UniRef50_A0A2N3G5L3 Pyruvate kinase n=1 Tax=Actinobacteria bacterium HGW-Actinobacteria-3 TaxID=2013648 RepID=A0A2N3G5L3_9ACTN  ali  34  12...................RAKIICTIGPSSNSTEILRHMIGAGMDVARINTGHADIEEVRRYIHVLKKAS-ESSNRRVGILLDLQGPRLRVGPI-KGSHLELEAGQRFTITTS---QRRGDETCVSIAYTGLTQNVKPGERIFIDDGLVQLVVRDI-SGNDVNCEVVEGGKLSRGKGMNFPDSNLSLASFTERDRRYLEAGLEAGVDWVAQSFVRSPGDIAQVVDAVHDLGYQVPVMAKIEKREGMANIDAILDAAQGIMIARGDLGVELPIEDVPLIQKELINKAVRAALPVVTATQMLESMVDEPRPTRAEASDVANAILDGTDAIMLSAETAIGQFPVQAVEMMARIASRTEQAVDYDRALEE--RARRAHRNTADAIGYAACKVAADLGAKAIVTITRGGYTARLVARYRPRAPIIAISPSEEVINSMSLVWGVQGVVAP------MAIDVATMIKNASGACVLKGLLRAGDLIVVTGGFLEESGKTNMIHTHTV 479
366 0.000e+00UniRef50_A0A0B6VT91 Pyruvate kinase n=1 Tax=Diplonema papillatum TaxID=91374 RepID=A0A0B6VT91_9EUGL  ali  45  9.TQLDHNIHLSVHKDTARQKVNIVCTIGPPSQSVEELKGLIKAGMTVARLNCSHGNHAFHRKTIQNVRKAAAEM-NVIIAIAVDTKGPEIRTGRFAVEGDVLMPIGHEIVLTVDPAFENACTKDIIYVDYPNIVDVIKVGQNVYIDDGLLALKVTAI-DGNQLKTVVTNPHKISSRRGVNLANVVVDLPPVSEQDVADLQFAVDNKVDLVFASFVTTPEQVRSVRKCLGD--SDIRIFSKISNAEGVEKFDEILAETDGVMVARGHLGCEIPLEKVFVAQKMMVSKCNAVGKPVIVATQMLESMMANPRPTRAEVSDVANAVLDGADAVMLSGETAAGDYRKESVEIMRKITVEGQLASREECLFESIKAVRSLPIQPDESIACAAVNSAYELQAKAIIALTELGLTASIVAKYRPMCPIVAVTSNSAIARRLVVHRFVRPVITDIQRNER-----EARIQFGIDYCKAENICRKGDRVVLIHG................ 485
367 0.000e+00UniRef50_A0A2H0PGQ8 Pyruvate kinase n=1 Tax=Deltaproteobacteria bacterium CG11_big_fil_rev_8_21_14_0_20_47_16 TaxID=1973975 RepID=A0A2H0PGQ8_9DELT :_  ali  37  3..................NHAKMICTIGPATNTPIRIRQLIQSGMRVARLNFSHAAHADHAKVIRIVREESNKLK-VPVAILQDLQGPKIRLGKIAEGTH-TLRPGDTFILTTHNLI---GNRQIASVTYKKLADEVSAGDTIFMSDGIMELKVTRVRR-TDVYCKVIQGGIIGSHMGLNLPNTRLSTPSMTAKDKRDLAFGIKMKVDYVALSFVRDASDVIRLRKMIKKLHGSARIIAKLELAMAVEHLDPIIEAADAVMIARGDLGVELPLEEVPMSQKTIIQHAFTLAKPVIVATQMLESMTIHPRPTRAEVSDVANAIFDGADAVMLSGETARGKHPLQAARTMVRIVERTERAIARR--HTSTLEHLPETAPVTEHLCYSASILAQHLGVKAIVAFTESGTTARYISKFHPRVPIYVLSPKHHVVNQSQLFWGAQSMFFRRGRHS------EALIRRMEHLLLSKKLVSHGDRIIMLLGMPLSSGPTNTIKIHTI 473
368 0.000e+00UniRef50_A0A2G6GP62 Pyruvate kinase n=7 Tax=Bacteroidetes TaxID=976 RepID=A0A2G6GP62_9BACT  ali  35  7...................RTKIIATVGPVTFDKTMLRKMFEAGVNVIRINFSHCDYEQAARTIQDVRDLNKEF-DVNVALLADLQGPKLRVGDIENDE-VFLEKDQILEFVSEKCI---GNAEKVYMSYEEFPQDVKQGDLILIDDGKLKLEVIETNGQNSVKAKVIYGGMLRSRKGVNLPNTDISLPSLTEKDIADAEFALSQNVDWLALSFVRAASDVIELKQLIKRKKKKVSVISKIEKKQAVSNLKEIIAETDAIMVARGDLGVEVSFDTVPLLQKDIVKQCIDAAVPVIIATQMMESMIENFRPTRAEANDVANAVLDGVDTVMLSGETSVGKFPIETIENMHKIIQYTEKERY--KYNQGTPPTPESKRFLRDNICYSASIMAERVGAKAIITFSEKGSSAKTISGYRPKADIYAFTRQEKLLSVLSLLWGVRGIYYEE------PDNIDEAIKKSINILKNKGCLKPGDRVIHVASTPLSVGHTNMLKVTKV 475
369 0.000e+00UniRef50_A0A2V7YR47 Pyruvate kinase n=4 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V7YR47_9BACT  ali  36  1.................MRRTKIIATLGPACSDEETIQQLLTSGVDVFRLNFSHGTAAERVRLVEIIRHVATEH-GKYVPIMGDIQGPKLRIGEV--EGVVHLLNGATFTITTRDIV---GNAGMVSTPFDNLPREVQIGHRILINDGLVELVVTAIDE-TKVATRVLHGGPISSRKGMNFPDTELTIPAVTEKDREDVRFAVEHQLDYIAASFIRRRSDIVELRELLQSLGSELNVIAKLEKAQAIDALEEILEASDGVMVARGDLGVELPPEIVPIVQKKILASASRWGKFAITATQMLESMTVSSRPTRAEASDVANAIFDGSDAVMLSAETASGSYPIGAVQMMARIIMAAEQNGGEARATREPFRQLSETDEFTDALAGAANYAAEQLEAKFIVVFTQTGFAARLMSKFRPKQPIIALTPSSWVARRMSILWGVQPFVLKEVGEFH-----EQIVERVDDFLLSRDIVSPGDRLVILMGSPIYQRKTNLLRVHRV 474
370 0.000e+00UniRef50_UPI0008114DE8 pyruvate kinase-like n=1 Tax=Rhagoletis zephyria TaxID=28612 RepID=UPI0008114DE8  ali  38  9.TLLEHMCQLQIDGPTVGRRTNIICTIGHATRDKEILKELIKGGMNIARLNFSHESHEQHKSSIDLVREASEEGYRRHIGIAVDTKGPEIRTGSFEGFFEVELKKNDNIRLSINKDLIDKGSKETVYVDYPNIINIVQPGNIIYLSDGAIMLLVKEVAVD-CVICQVEVGGILGAAKGVWLSRVNIDLPPVSEKDRYDLRFAVEHNIDFIFASKIRHPAAIREIRAVLGERGKDIQIISKIDCAQILNYLDEVILASDGILIDRSSLGIEVRDEKLFLLQKAIIARCNRVGKPVIVGTQILSSMNTESRPTRSDVADLGNVVLDGVDGVMIASESAIGKYPLETLNRLASICAEAEAAIWHRHLHHELLLNNPAVIDAVHAVALAAIDSAQRSMAALIVCLTTSGRSAYMLSMYRPHCAIIALTRCSRTARQCHLRRGVYPVLYLEKPDPDYQKDVDLRVQYALVAAKKAKLVDKGDSVVIVSPWKEGTGFANNLRI... 509
371 0.000e+00UniRef50_A0A1F3T479 Pyruvate kinase n=2 Tax=unclassified Bdellovibrionales TaxID=404130 RepID=A0A1F3T479_9PROT  ali  33  7..................RKVKIVCTLGPSSRSPEMIRALIDDGMDIARLNFSHGTHDFHRGLIATIRDAARA-ANKQVAIMQDLQGPKLRLGKV-GPEGIEIKAGDIVLLYPEGATPRLSTHGKIPIPSAEIAQDTQVGARILFDDGKFATRVIQV-EPPELVVEVEVGGKLTSNKGMNLPGTPLSMPCLTEKDIEDLKFGLSQNVDGVALSFVRNVQDIEILKQYMKDTMKLPHVVAKIEREEAIEYMDSIIEVVDGLLIARGDMAVEIGAERVPAVQKQLIHSCNEVGVPVITATQMLESMISSPTPTRAEASDVANAVFDGTDAVMLSGETASGQYPREAVQTMVRVILEAERSM---ETYSRHRRTNPMPGSVVEAIESAASSIAGQVGAVAIACITHSGVAARTLAKYRPETPVLAIMDNEENLRRLAFVWGIRGALIPKIVG------TDDLFSMVEKVLVGNSWAQTEDLVVVTAGVPLRKGTTNMVKVHRV 483
372 0.000e+00UniRef50_A0A1L7BFE3 Pyruvate kinase n=24 Tax=Thermotogae TaxID=200918 RepID=A0A1L7BFE3_9BACT  ali  38  1.................MRKTRIVSTIGPATELEEMLEKLIKTGVNVFRLNSSHDTXXX-XXXXXXXXXXXXXXXXXXFAILIDLSGPKIRTGKL-KEEYITLKENSIVDITTDDVL---GDEKLLSVNYVRFPFEVKKGDKVLINDGAIELEVLETN-NNIVKTKVIRGGRITHHRGVNLPGVDLSISAITEKDKEFIKLAIEENIDFIALSFVRKPEDV----KLAKSLSNGIPVIAKIETAQALDYLDEIIHEADGVMVARGDLGVEIPLSKVPIVQKQIIETANRYAKPVITATQMLESMIKNSTPTRAEVSDIANAILDGTDAIMLSAETSIGDYPIEAVKVMNEVAINTEKFLNYESIELEWIRSYYISEDPETAISHAVYNLSKDINAKLIITATGTGRTAINVARLRPNVPIMAATPNISTLYKLSLVWGVIPVLI------NQTLSTDEMINEVMKKAKELGFAKKGDKVIITAGIPWGPGTTNTLQIQEI 469
373 0.000e+00UniRef50_Q1D6L5 Pyruvate kinase n=23 Tax=Bacteria TaxID=2 RepID=Q1D6L5_MYXXD  ali  35  1.................MRKAKIICTLGPASDTPEVIEGLIRAGMNMARLNFSHGTHEEHRRRVETIRKVAKRL-GTPVAILQDIQGPKIRLGRF-DGGQLLVKQGQSVTVTTRNVLGQDG---VIPTPIKSLVKDVAKGHEILLDDGRVRLRVLRVH-GQDVQCRVEVGGVLKNHKGLNLPGSPMSVPTITRKDAVDLAFGQEVGVDYVALSFVRTPEDIKKARAHVAKL--KTPLIAKIEKPQAVERVEEIAAVADGIMVARGDLGVEMPLERLPAIQKHMVSAVNRMGGLVIVATEMLESMVANARPTRAEVSDVANAILDGADAVMLSGETAAGKYPVEAASTMACIVEETERGVVKHQHHSPFERSEDLGTGVAAAAVAAATQL----GIGTIVAYTESGHTARLISEFRPHARIIALTPSETAVNRMALYWGVTGMQVARVST------TDAMLTQVRQLCRKEKLCAPGTPVVVVAGVPLNPGNTNLMSIHRI 466
374 0.000e+00UniRef50_A0A2K9NQU3 Pyruvate kinase n=6 Tax=Bacteriovoracales TaxID=2024979 RepID=A0A2K9NQU3_9PROT  ali  36  2................PMRRAKIVATIGPASNTKEMISKLIETGVNVCRINMSHGTYEAHSAVIKNIREASRE-SGYEVAILADLQGPKIRVDKLP--EPLKLEEGSEWVIGASKDKYPEYAQNYIPTIYENLVADCHDGARILFDDGL--LQAVAVNRDRDVKIKVKIGGTLKSNKGINLPDCEVSAPAFTDKDREDLMFALKEGADYVALSFVRKKEDIMQVKTLLHTLKVNIPIISKIEKPQAIDNLDDILSVTDMIMVARGDMGVEVGNHLVPAIQKKIITECNNKGIPVITATQMLESMTENPTPTRAEASDVANAIWDGTDAVMLSGESASGKYPIETVRMMDQIVREAERTPKERPLLRH-----QDLSSVTASVMVAASMIAEKIGARRILSVTESGQSCLRITQFRPSIPVLGITNSIKVARRMCLYWGVSPFIVTDQERENN-----EFMKNVLKEVKDRLKLKNGDKLVVTRGDFFSQGSSNSVKVELI 475
375 0.000e+00UniRef50_UPI000BAF01E1 pyruvate kinase PKM-like n=1 Tax=Crassostrea virginica TaxID=6565 RepID=UPI000BAF01E1  ali  39  10.TRLEHMCGLEIDKPHKARLTSIIGTIGPACDSVETLRAMIKAGMTICRLNLAYRTHEYFKGAVQRIREAQAGLDFIQVGIGIDITGTGIRLGSLAKEEELKMKTGDKMRFSIDEKYCEHGNENVMFFEAALVFDNIKTGSKVIIEDGPLTLIIKEKGED-YVDCEVEEPGELGSHMMWTIPNMVMREVKLSEKDKKDLQFAVDHDLDMVFASWVWCPEMVVEVRNFLTERSKSMKILAKIETHTAIKRVDEILEVADGLYLARGNLGINISPEKVFLAQKMLIGKANKAGKPVICATQMLGSMMWNARPTRAEVADVANAILDGADCVMLSRETARGKYPLKSMETMSAVCREAEAAIFNEDVFYALKRSVRITGN-THTTAIAAVEAAHKCHAKAIMVITVSGRSPALISKYRPNCVIVAITRSKHTARNLQLHRGVFPVLHSDAKDSVWADDVDARLHHGIQMARHLNYIQSGDMIVLVTGWTSGAGSTNTIRIVT. 511
376 0.000e+00UniRef50_A0A1Q9NC55 Pyruvate kinase n=1 Tax=Candidatus Heimdallarchaeota archaeon LC_3 TaxID=1841598 RepID=A0A1Q9NC55_9ARCH  ali  37  10...................KTKIVCTLGPSSNTESMLKKMIKAGMDVVRINFSHGSHEEHEKTIKMVRKVSED-----IALLCDLSGPKFRIGEVKN--AFEINPGDKLILTADEVI---GDENRISVNHKLLPQEVKVGNELWINDGLVMLEVTSIKNNVDIYTTCKVGGPISSRKGINAPQVPVSLFFPTKKDINDAKFALEYDPDYFAASFVRKANDLIPLRELIEKNYKHTHIISKIEHREALKNIKEIIKASDGIMVARGDLGLEIPTEDVPIVQKDLIKQCNIYSKPVITATQMLESMTINKRPTRAEASDVSNAVLDGTDAVMLSGETSVGKFPVETIEYMNRIAHRAEEVITSDLK----RITHYSEETLSGVLGHAAQYTASKLDLGAILAITRTGSTVRLVSSHRPKIPIIGATSFPTTFRQLQLVWGVEPLLIDIKTS------TDKIILESVEKSLDNHYIKEEDKILVIAGTLLGPAKTNLIQVMDV 471
377 0.000e+00UniRef50_A0A1J5IRS7 Pyruvate kinase n=1 Tax=Candidatus Wirthbacteria bacterium CG2_30_54_11 TaxID=1817892 RepID=A0A1J5IRS7_9BACT  ali  37  6....................TKIVCTIGPASGDEETINKLYLAGMNVARLNFKHGDYAWFSDVIDRIRKVSKAH-GEPIAILQDLQGPDIRTGFLVDHQKVELVPGKPFFLTSKKI---EGSSQGVSISLSHLNKYMAEGDHVLIDDGAIDLIVNSVDSETA-HCVIVNGGLLSERKGLNIPGKRPQVEPLNPKDLDDVAFAIEHKIDFIALSFVQSADDVQKLRNLLTESNNDIQIISKIESVSGLKNFASILEASDGIMIARGDLGIELPIEQIPAIQKELIQKCNQAGKPVITATQMLDSMEHNPLPTRAEVSDVANAVLDNTDAIMLSGETASGMYPVEAVLTMARIVKHTESKLQDGTL--KRRTHFGEIKTVTESVAKQACDLAREIGAKLILTLTTSGATTRNVARFRPGIPIKGASPYGIVQRQLLLVHGVTP----DSLRVHPDKNFKVMADEAIALMKNSDQLIPGDIIVITAGIKGKAGSTNLIYAHIV 480
378 0.000e+00UniRef50_X4RAD2 Pyruvate kinase n=1406 Tax=root TaxID=1 RepID=X4RAD2_9ACTO  ali  36  1.................MRRAKIVCTLGPATDTKERIVELVKAGMNVARINASHGSHAEHEQRIDMVREAAEEL-GEAVAILVDLQGPKIRLGTFESG-PVLLEQGDIFTITTEDV---PGDKDLVSTTFKGLPGDCRPGDLILIDDGKVQVRVVSV-EGPEVKTEVIIGGTVSNNKGVNLPGVAVSVPALSEKDKVDLEWALNYGADICALSFVRSAEDVKDVHEIMDMVGRRIPVIAKIEKPQAVTALEEIVSVFDGIMVARGDLGVELPLQQVPIVQKRAISIARRNAKPVIVATQVLESMITSPTPTRAETSDCANAILDGADAVMLSGETSVGKYPIACVETMASIIQFTE-----EHGLESIPKIGNLHRTRNGVITRSAMDIGEALGVKYLAVFTSSGQTARRMARLRARIPLLVFTPSRDIRQRLALTWGAQTIIVPE------VEDTDHMIEQVDQALRDRGYAVDGDRVVVVSGMPAGVGSTNTIRVHK. 466
379 0.000e+00UniRef50_A0A292RRW8 Pyruvate kinase n=10 Tax=Bacteria TaxID=2 RepID=A0A292RRW8_9BACT  ali  36  1...........MDSKIKREKTKIVATLGPSTSNYEMISQLVEAGASMFRLNTSHGTEEGHAANIEIIRKISQE-TGKYIPILIDLQGPKIRVGNIPN--PIEIKEGQEIIL---EATDEVNNPDILPVDYEGIADDVKSGDKILLDDGNIGLVVTGV-SNHQVHAKVLYGKLIKPRKGINLPGATASLSAVTERDVEYIRFAVEYDADYVALSFVREAKDIELAKKYIKDYGGNIPVIAKIEKPQAVENLEEILKVTDGIMVARGDLGIEMSPEEVPIVQKYIVDQTIRERKVCIVATQMLESMIENPIPTRAEASDVANAILDGTDAIMLSGETAMGKHPVEAVKMMRKIATNVEDCNFCLSNLD--LEMNDKYDLSPQAISNAAVKMAQDLNAKAILAFTHTGYTPKLLSKLRPTVPVIAISDMESTCRRLSLYWDI----VADYKQWDTVLDAD-LLEKIDEYILTRTDYKKGERIIIIGSIPLITGRTNFIRVHRI 476
380 0.000e+00UniRef50_A0A1L6M2D7 Pyruvate kinase n=1 Tax=Minicystis rosea TaxID=888845 RepID=A0A1L6M2D7_9DELT  ali  32  7.................VRKAKIVCTIGPACDDQASLEQLIRAGMDVARLNFSHGSHEEHGRRFATIR-AAAEACDKPVAILQDLCGPKIRCGRFPGGTR-TLPSDTIVSLVEAGNEGMAG-PDEIPIQYEGLAQDLQPGDVILLDDGRVVLTVTSIDNGR-VRAAVTQPGTIRDRVGVHLPARRVRIATLTEKDKADLSFGLSLGVDYVALSFVRHPDDVRLVREICEAWGRPTPIVSKIETPSAIDHLEALILASDGVMVARGDLGVEFPPERVPIIQREILGLARVHQRPVIVATEMLQSMVTATRPTRAEASDVATAVFEGTDAVMLSQETATGQHPSLVARMMARIITEAETSKFYQPLSSELPGQRAQ---VNEAVARAACDIGRDIGARVIVAFTESGLSARYASKARPNVPIIAFSPNPVTCRRLALVWGVVPCPLDQFRSP------DEMVDRASAYLNSHGFAAPGDKFVAIFGAPVGVGTTNCIRVRVV 477
381 0.000e+00UniRef50_A0A058ZLD1 Pyruvate kinase n=1 Tax=Actibacterium atlanticum TaxID=1461693 RepID=A0A058ZLD1_9RHOB  ali  35  2.............SKPP-RNTKIVATLGPASCDPNVVQSLAETGVNVFRLNMSHGDHSTIAAMHKAVRDAERVL-GRPIGILADLQGPKIRCGEFSEG-PYLLRPGQEFTFDTESQL---GSAERVQLPHPEVISALREGSAILVNDGKIEMRV-EKAHKEHVLCKVEIGGEISNRKGVNLPDVMLPLSALSSKDRADLEFVSDLGVDWLALSFVQRAEDVAEAQALLK---GRAKIVAKIEKPAAVENYSQILRQADGIMVARGDLGVEMPVQEVPRIQKSLLAQAKAAGKPVIVATQMLESMIEAPVPTRAEVSDVATAIYDGTDAVMLSAETAAGKFPLEAVRVMVAVAHETENDPRYAALMKE-RSDDLDDLDTSHAIAAAAREISDRARVSAICCFTQSGTTAFLVAREKPAKPIVAMTPNVQTARLLTLVWGLRSVVVP------QAEHFRDAVQSASEQCKQLSLAQPDDEVVVTAGVPIGAGTTNILRVTRI 472
382 0.000e+00UniRef50_A0A2G6DRX2 Pyruvate kinase n=23 Tax=Parcubacteria group TaxID=1794811 RepID=A0A2G6DRX2_9BACT  ali  39  2..............KKNLKKTRIVATIGPASENPVVLKKLIDAGLNVARMNFSHGDHVEHSERXXXX-XXXXXXXXXXXXXXXXXGGVKIRIGDFVDG-SIDLKKGQKFIITSKKC---AGNNKKVSINYKKLPKEVEVGQSILIDDGTKELCVT-KTTDTEIETKVVTGGMIQSRRGVNVPGARLSCSALTAKDKKDIEFGVKNNVDFIALSFVRSAKDVLQLRRILDKYKSDANIIAKIETPEAIENIDGIISVADGIMVARGDLAVEMPACDVPHLQKMIVKKCNIVGKPVIVATQMLESMITAPVPTRAEVTDVANAILDGADAVMLSAESAMGKYPLAAVRTMASIAKRTEKEISVKM----ITDIQKYASRTVNAVSRSAIYIAEDIGAVAIVALTESGFSARKISRYKPRQDIIALTPRKKTHQNLQLSYGCFSHVIDRFHS------VVETVAFVKKFVKKNGYAKKGERVVIVAGVPFEAGTTNMVIVEEV 473
383 0.000e+00UniRef50_A0A2V3JJY6 Pyruvate kinase n=1 Tax=ANME-2 cluster archaeon TaxID=2056317 RepID=A0A2V3JJY6_9EURY  ali  37  12................TIRRTKIVCTTGPATESEESLRQLTRHGMDICRLNMSHGMHEWHARQIRVVRTLSNE-QNRAVAIMLDIQGPKIRTSRVQGG-SVVLRAGDDLTI---NSSDIIGDARHIGVRYPLFAKEVSKGQTIMIDDGRIRMVVVGT-DGVCVEAKVVVGGVLTDKRGVSVPEAHFSVPSVTEKDKKDLSFGIEHNVDYIAVSFVRRASDISGVKQMIHEQGADIPVIAKIETKKGLDNFPEILKVADGIMVARGDLGVEIPIEEVPVTQKRLIAESNASGKPVITATQMLESMIHDAIPTRAEATDVANAILDGTDAIMLSGETTVGNYPIESLIMMDRIARTTESVGW---RVRTEADADATELSIERSIGHAVCQLACNLNAAAIITTTYSGSTATVVSMYRPKTPIIAITPDKVTFHRLALIWGVTPLIIPV------VETIDEAMDASVQSAMDAGFVKPGDRVVLTTGVPFVSGTTNLITVRVV 481
384 0.000e+00UniRef50_D6WCE5 Pyruvate kinase n=2 Tax=Pancrustacea TaxID=197562 RepID=D6WCE5_TRICA  ali  47  1.......................................MIEAGMNIARLTLSHGTQEMHTELIQNVRTAVENYSKRPLSLALDIKGPEVRTGYMEGGAEVELKKGEQIKLTTDKAYLEKGSSSVIYVDYDNIQKVVQPGNRIFLDDGLISLICTSVQ-GSVLTCSVENGGMLGSCKNVNLPGIDIDLPVVSEKDKEDLLFGVEHGIDTVHASFIRNAVDVSEVRDVLGRAGNKILIISKIENHQGVHNIDEIIKASDGIMIGRGDLAVEIGPEKLFLAQKSIIAKCNKAGKPVICANQLLYSMIKRPRPTRAECTDVANAVLDGVDCVMLTGETFLGQHPIECIRAASKICKEAEGAIWYKHHFRELIGHARPPLETSHTICIAAVEAANQCLAAAIIVTSVSGRSAHSLAKYRPNCPIILVTRDPTVAKQANLFRGIIPLFYEVERKDDWRRDIEARISFGISFGKWRGF............................ 439
385 0.000e+00UniRef50_A0A2N2GV29 Pyruvate kinase n=1 Tax=Deltaproteobacteria bacterium HGW-Deltaproteobacteria-22 TaxID=2013750 RepID=A0A2N2GV29_9DELT  ali  36  11................KMRKTKIVATLGPATADDDILARLIAAGVDVVRLNFSHGTHEGHAQSFARV-KAEALRQKKHVAVFGDLCGPKIRTGDLKDG--LFLSSGDEVVLVPE------GHSGGIGITNEECFTDVQVGEPVMLDDGYLAFEVTRKERDKLI-CRVVTGGRLKSHKGVNFPSTTLSLCALTEKDREDAYFGLDLGLDFFALSFVQTPEDVMELKQICGRTG----VIAKIERPVALTNLEGILSVADGIMVARGDLGVERGFEHVPAIQKRLIRESRLRAKPVITATQMLESMIQNPTPTRAEVSDVANAVLDGTSAVMLSAETAAGQHPIEAVKMMARIIDAVEGDSY----FETVPLQFQAATTFTQAIANAAVSAITNLDVRLIAVFSQTGETARELAKFHPRVPVVALTSRLEVLACMSLEWGVVPLYCPALSTPA------EMVQSCQSLLLENGLVRSGDRIAISMGFVDGAGRTNTLKLHVI 471
386 0.000e+00UniRef50_A0A2H5VGA2 Pyruvate kinase n=1 Tax=archaeon HR06 TaxID=2035442 RepID=A0A2H5VGA2_9ARCH  ali  39  1.................MIKTKFICTIGPSSSKPNIIRRLIKEGMSIARLNFSHSTPEEHFKLLKIIRREAEKL-NKPLGILQDLPGLKLRIGKLK--KKIYLRKGDVITLAID-------DENSIPVNFKDLPKVVKVGGQIFLSDGLIRLIVLDKDE-KSLKCKVMNDGELVSGKGLAIPNLKMDIPSLTEKDIEYLKFGLKIGVDFIALSFVRNSRDVLLAKDLAK---KDAFIISKIERGEALKNLDEIIEVSDGLMVARGDLGVDIGFEKVPVVQKEIIAKCNKLGKPVIVATQILDSMVNNPIPTRAEVTDIANAILDGADALMLSDETAIGKYPIDALKMLAKVSKKIEEKIFNLRENES--------KELSEVVSYVACKAGIELKVKALVAPTRSGLTARRLSKYRPPFPIIALTPNEKVERILCLFWGVFPYKTKEF------ESIDAMLEEAERIVKEDKIAKGGDRIIIVSGDPKGVGETNLIKVHRI 456
387 0.000e+00UniRef50_A0A2R8PCW8 Pyruvate kinase n=1 Tax=Callithrix jacchus TaxID=9483 RepID=A0A2R8PCW8_CALJA  ali  48  1.......................................MIKFGMNVAHLNFSHGTHEYHVETIKNVCAAMESFAYQPVAVALDTKGPEIWTGLIKGSAEIELKKGATLKITLDNTYVEKCDENIPWLDHKNICKVVEVGRKIYVDDGLTSLQVKQKGAD-FLVTEVENGGSLGSKKGVNFPGAAVDLPAVSEKDIQDLKFGVEQDVNMVFASFIHEVADVHEVRKVLGEKGKNIKIISKIENHEGVWRFDEILEANDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNRAGKPIICATQMLESVTKKPRPTQAEGSDVASAVLDGADCIMLSGVTAKGDYPLEAVRMQHLIAREAEATIYHLQLFEELCRLAPITNEPTEATTVDAVEASFKCCSGAIIVLTKSGRSAHQVARYHPCAPIIAVTRNPQTARQAHLYHSIFPGLCKDPVQEAWAEDVDLQVNLAMNVAKAQ-VTAKGDY...................... 444
388 0.000e+00UniRef50_A0A158EKG2 Pyruvate kinase n=3 Tax=Burkholderiales TaxID=80840 RepID=A0A158EKG2_9BURK  ali  32  431..................RNAKIVATLGPASTSRETIEALFNAGADVFRLNFSHGTHEDHQLRLKIIRSIEKD-AGRPIGVLLDLQGPKLRIGTFANG-PIKLEKGAKFRLDLD--ASTPGDIHRVALPHPEIFAALKAQTNLLLDDGRVQLRVERCGPDFA-ETFVVVGGPLSERKGVNVPDVVLPLSAMTDKDRRDLEFGLTLGIDWLALSFVQRVEDIREVREIVGDR---IGIVAKLEKPAAIGSLDAIVDEADAVMVARGDLGVEMPSEQVPAIQKRIVRACRKAGKPVIVATQMLESMVTAPVPTRAEASDVATAIYDGADAVMLSAESASGKYPVEAVRTMDLIITQTESDPYYREVI--TTSHAAPRANTADAIGYAMRHVTSLLNAVATVAYTSSGYSALRMARERPAAPIIGMTPREATARRLALAWGVHPVLCDEVI------DLLEVSELACATVRDEGFGETGQTVVISAGMPFGPGTTNLLRIAQI 897
389 0.000e+00UniRef50_A0A2E4E3N2 Pyruvate kinase n=5 Tax=unclassified Rickettsiales (miscellaneous) TaxID=1699067 RepID=A0A2E4E3N2_9RICK  ali  33  3................RQRNTKIIATLGPATSSPSSIDNLYRSGVDIFRLNFSHGSHSEKRKLVYQIRQYEKRL-DRPIAILGDLQGPKFRIGNFHK-KQIFLKSGDKFTLDLN---LSDGDENRVCLPHPEIFKSLKKNSTILIDDGKIQLKVFSVHSDK-IQTEVAIGGKISNHKGVNIPNILIKTSPLTKKDILDLDLCVDLSLDYIALSFVQRPTDILKLRKIVKKN---TAIMTKFEKPLAIEKMEEILKYSDAAMVARGDLGVEMPPEEVPIIQKRLVQKCRDLGKPVVVATQMLDSMINSPSPTRAEASDVATAVFDSADALMLSAETAAGKYPFESVKIMDRIIRGVESDSSYRFFINS--KKVKLEETTSDAISAAASQVVNTVLAKAIFTYTRSGKTAIRAARERPSVPIIGLSPERLTARQLSLIWGVHSIHANEPKSFSG------MIDNACELAKKEKIVRRGDCVVITAGAPIGVGSTNNLRIAKI 470
390 0.000e+00UniRef50_A0A1E5VB24 Pyruvate kinase (Fragment) n=1 Tax=Dichanthelium oligosanthes TaxID=888268 RepID=A0A1E5VB24_9POAL  ali  43  85..............DARVPKTKLVCTLGPASRTVPMLEKLLRAGMNVARFNFSHGTHEYHQETLDNLRQAMH-NTGILCAVMLDTKGPEIRTGFLKDGKPIKLTKGQEITVTTD--YDIKGDENMIAMSYKKLPVDVKPGNVILCADGTISLAVVSCDPDGTVRCRCENTAMLGERKNCNLPGIVVDLPTLTEKDKEDILWGVPNDIDMIALSFVRKGSDLVTVRQVLGQHAKRIKLMSKVENQEGVVNFDEILRETDAFMVARGDLGMEIPVEKIFLAQKMMIYKCNIAGKPVVTATQMLESMIKSPRPTRAEATDVANAVLDGTDCVMLSGESAAGAYPEVAVKIMARICVEAESSLDHEAVFKAMIRSAPLPMSPLESLASSAVRTANKAKAALIVVLTRGGTTAKLVAKYRPRVPILSVVSSEGPARHSLIYRGLIPLLAEGSAKATDSESTER.......................................... 565
391 0.000e+00UniRef50_A0A1Y6BNJ8 Pyruvate kinase n=1 Tax=Pseudobacteriovorax antillogorgiicola TaxID=1513793 RepID=A0A1Y6BNJ8_9PROT  ali  34  13.............EPNLVRHTKIIGTLGPSSSDYETQKKLVEAGLNIARLNFSHGDHATHLKNIHSIRQIAQE-TGKPVAILQDLQGPKIRVGKLMGDQ-MQIVKGETYSLRYGVEQKE---AKVIPIDYRGLTHDVSKGQRVMMDDGLLILEVTDVKHDT-VHVTVQEGGTLKNRKGVNFPDSKLSLPAMTDKDSKDLLFGIANNVDYVALSFVQDPADIRQIKSMIRALGSDVPVVAKIEKLPAIDTIDEIAQEADGLMVARGDLGVEANVERVPNLQRTIIRAATKHGKPVIIATQMLESMIKNPRASLAEVADVANGVLDGADCLMLSGEVASGRYPVQAVKRMSDIIKEVEAWTFKRPRFSLQERPSRKDWEVNESIALSACEAADALNAKAIVCLTLTGSIARSISKWRPKTPIIAISPRKDVSQRLEMVWGIQGI------PNPSFYNTDSLLQELPRVLKELNVAESGDVVVITAGIPINKKPTNMIKINRI 489
392 0.000e+00UniRef50_A0A2E5S2J7 Pyruvate kinase n=8 Tax=Bacteria TaxID=2 RepID=A0A2E5S2J7_9LEPT  ali  39  1...........MSSRRDFRLTKIICTIGPATASSETMARLARAGMNVARLNMSHGDHESHGQVIRQIKNLNKKL-NHPVAILMDLQGPEIRTGELP--ESLNMNVGDIFTFTVTPATDAE--EHTVHVNYRDMARDLSPGDRITVDNGLINLEVLSIXEGRX-KCRVLEGGQLGSRKHINLPGVRVNLPSITEKDKKDIRFAVENDLDFVALSFARRAEDVLEARQIIEDLDGHAQIIAKIENQEGVDNFREILNVCDGVMVARGDLGVEIDIEELPIVQRQMVQSCVLAGKPVIVATHLLESMIENPMPTRAEATDVANAIYEQADCVMLSGETATGKYPVKCVQMLDRIARRMEKEPGIGFATHRV------PLDTREELARSAVQLADSIHAPAILVITRRGIFARQVASFRPRSSIIAFTNMSSTRRKLWSVRAVVPFLMD------FSSDPEKTIQSALEKLRQRNRVMAGDPVVIVSDVAAGNERVTSIQVR.. 470
393 0.000e+00UniRef50_Q04N91 Pyruvate kinase n=205 Tax=Bacteria TaxID=2 RepID=Q04N91_LEPBJ  ali  38  6...............SVIRKTKIICTIGPATADKKMIQALAEAGMNVARLNMSHGNHDFHRSIIRNIKSLNKDILKNPIAILLDTQGPEIRTGDLQVD-HLDLKVGETFVFHI--IPGEESEEQSVFVNYKDIVKDLKVGDPVTVDNGLINLIVEEIN-DSALKCKVLDGGKLGSRKHINLPGIRVNLPSITPKDHKDILFGLEEDVDFIALSFVRSAEDINQLKQIIEENEGHAQVIAKIEDQEAVRNMKEIVEVSDGVMVARGDLGVEVPIEELPILQRAIIKECALKGKRVIVATHLLESMINNPSPTRAEVTDVANAVYEEVDAIMLSGETAAGKFPIRCVEMMDKIAQRVEKAGGVDYV------KDKIPQDKKEQMARSAAELADSLKCPAIIVITRRGTTALNVAGFHPHYPIYAFTNMTTVRRKLWLTRGVIPYRID------FSKDPEKTIRLAIETLKKAGKIEDGDQVVILSDIIAGEDRVETIQIREV 475
394 0.000e+00UniRef50_E8N5X3 Pyruvate kinase n=11 Tax=Chloroflexi TaxID=200795 RepID=E8N5X3_ANATU  ali  36  3..................RRVKIIATLGPACENAETIRAMAEAGMDVARLNFSHGTHEQHAQRIQTVRQISKEL-GKEITILQDLQGPKLRVGVLP-ENGVDLYPGELIVLTSKKELPEPHSAKILPMDVPNLEASVHEGSRVLMDDGNLELRVKEVTPD-YIISEVINGGKLRSQKGVNLPEANLGIEGFTEKDQADLMFGLEHGVDAVAMSFVRTAEDIRTVKRAIEEKCSVPLVIAKIELPEAIQNLHEIVHEADGVMVARGDLGVEMSLAEVPTLQKEIIYLANRHAKIVITATQMLETMIQNPRPTRAEASDVANAVFDGTDAVMLSAETAAGKYPVEVIRTMASIVTDAEMNYTMWGHYKDLPREAVQSD--ALSITWAARELAHDRDVRAIVVFTETGRTALYTSKSRPAVPILAFTPVQETLQKLGLFWGVSAHLVP------FANSVESMIQIVEEMLLGKLGFSKGEQIVLISGLPVGA........... 467
395 0.000e+00UniRef50_A0A2T7PSS0 Pyruvate kinase n=2 Tax=Pomacea canaliculata TaxID=400727 RepID=A0A2T7PSS0_POMCA  ali  38  14.SALTQLCGLDVDSGIRFRMTPIICTIGPSCENIKIIAEMIEVGMNICRLNMAHGTFEYHSQLIKNVREAMSQHSPSPVAIAVELGGQGVRCGCFLPGEEVKFKKGDVVILTNEKELQDKCDRSVLYINSQYYLNLAKIGHKIWVGDGLLSFVVKEKLNHGKLRAEVDTEGEISNLDHCIIPRVP-PAPTLTDYDKECIKFALAHNVDMIFASWVWSESIIKEIRSMLGDKGAKMKIIANIENYMGVKNFNEIVEAADGVMVARGDLGMDLPPEKVFLAQKNMIGRANVAGKPVICAAQMLDSMVKNPRPTRAEAGDVANAILDGADCIMLSRETAAGRYPVLALKYACAIAREAEMAVHHDRVYRQLRASTPLPVDSTHCTAISAVEASIRCQASAIIVVTNSGRSAGVVARYRPPCLIVAVTKSQHTVKLLHLHRGIYPVLHDAASCGEWIDDIDFRINHALIICKRRGYVKAGDYCILVTGSMEGPGWTNTVRTISV 517
396 0.000e+00UniRef50_A0A2D6JLT3 Pyruvate kinase n=2 Tax=Bdellovibrionaceae bacterium TaxID=2026715 RepID=A0A2D6JLT3_9PROT  ali  36  5..................RRVKVVATIGPASNSKEKLKSLIEAGMNVARLNFSHGSHEDHIQVIKNLRELSKELR-APVSILQDLQGPKIRVGKFENG-FISLEVGQKVRISPS---FELGKGSDISTDFPTLHKDVSQGERILLDDGLIELAVDSV-EGDIVNATVIYGGKLKDRKGMNVPGANLSVDCLTEKDLKDLAFGLEQQVDYVALSFVRSSEDMLRLRKLVDEKSPKTKTVAKIEMLEALDDLQRIVKKSDAIMVARGDLAIEIGQTRLASVQKKIIKECNRQMKPVITATQMLDSMVNNPRPTRAEITDVANAILDGTDALMLSAESAAGNFPAECVSTMHEISMEVEK----ESASYYIRKKKSNFETVPESIAASASLTAEVLDAKVILCLTTSGKTATFISGFRPKAQIIAATHITDTLNRLELVWGIQTIKIEPY------DDVESLIARLQSKIHALGLADFGEKVVLTMGQPIRSGKTNTVRVFTI 471
397 0.000e+00UniRef50_A0A1V5EDX1 Pyruvate kinase n=3 Tax=Deltaproteobacteria TaxID=28221 RepID=A0A1V5EDX1_9DELT  ali  34  1.................MRKVKIVCTLGPSAAGIPRLKQLVEAGMDAARLNFSHGTHEEHRRMFLDVRAAALQ-AGKPLAVIADLCGPKIRVGPVEGGG-VALKPGQPIILAAGN---RAGNADRIFHSYPPLSREARRGDRILLDDGMLEFVVESVRGD-EVLCRVVTGGVLKDHKGMNLPTMKLSAPALTEKDREDLRFARELGVDYLALSFVRTPEDIRAAKELAG----GTPVIAKIEKPEAVARLEEILEAADGAMVARGDLGVEAGPEKVPLLQKRIIRDIRKFAKPVITATQMLDSMIRNPRPTRAEVSDAANAVLDGTDAVMLSGETSVGQYPVEAVQTLRSIIEEIESGRMRLPCPEPGERDVPAVHAFSSAIADACVEASRCLKLAALAVYTETGRSAALVSAQRPEASVIAFSRHPQVLNRLALLWGVKPL------NGQWVKGVAGVVEQAEAELLRHGLVRPGDDIAVTFGMVIGSEQTNILKLWKI 476
398 0.000e+00UniRef50_K6ULG9 Pyruvate kinase n=144 Tax=root TaxID=1 RepID=K6ULG9_9MICO  ali  37  1.................MRRAKIVCTIGPAVDSPEKIRALVDAGMDVARINRSHGSYEDAERHIALVRRAAEQ-AGRQVGVLVDLQGPKIRTGRFATG-PVLLNEGDRFTITIDDI---EGDGERVSTTFKGLTGDVRAGDTLLVDDGKITLRAVEVTP-TDVVTEVVEGGTISNNKGINLPGVPVSVPALSEKDEEDLRWALRIGADWIALSFVRDARDVIRCHEIMEDEQVRRPVLAKVEKPQAVANLAEIIRAFDGIMVARGDLGVEMPLEEVPLVQKQAIALARREAKPVIVATQVLESMIDNSRPTRAEASDCANAVLDGADAIMLSGETSVGSWPINAVRTMARIIENTE-----DHGLSRIPPLGTEPSTVGGAVTAAAARIGNSLQAKYLVCFTSSGDSARRMSRVRSGLPMLAFTTDAETARRLTLTWGIRAFIVPQFSHMST------MVEAVDQALLAEGVVTQGDVLVVVAGRPFGSGTTNSLRVHVV 467
399 0.000e+00UniRef50_A0A2D7IEY8 Pyruvate kinase n=2 Tax=Alphaproteobacteria TaxID=28211 RepID=A0A2D7IEY8_9RICK  ali  35  5..................RNTKIIATLGPATSSPSRIHSLFKAGADIFRLNFSHGTHADHRNKVFHIRQYEKRIR-RPIAILGDLQGPKLRIGKFSK-AYFILKEYEKFTFDLNEEL---GNNKRVNLPHPEIFSSVKNNSQILIDDGKIKLHVIRASSDK-IETEVINGGKISNNKGVNIPETFIKLSPLTEKDFKDLELCLDLSVDYVALSFVQKAQDIVKLKKL---TGHKTGIMAKFEKPLAIEKMEEILYSSDAAMVARGDLGVEMPPEEVPIIQKRLIQNARNQGKPIIVATQMLDSMINSPSPTRAEASDVASAVFDSADGLMLSAETAVGKYPVESVRIMDRIIRGVENDSSYRQILDSKKLNLEQTTS--DAISSAASQVVKTVSAKAIITYTRSGATAIRASRERPPVPIIGVSPERSTSRQLALIWGIHNIHALEPKSFSG------MINNACELAKKEGIVKKGDSVVVTAGAPIGSGSTNNLRIAKI 470
400 0.000e+00UniRef50_A0A2A5XRF3 Pyruvate kinase n=5 Tax=Bacteria TaxID=2 RepID=A0A2A5XRF3_9BACT  ali  37  7..................NRTKVIATIGPSSSGYDTLKEMIKNGVDVVRLNFSHGDYKDHKQTILNVRKISDEL-GLPVSILQDLQGPKIRVGKLNKDE-IELSDGHQFYITSDNIV---GNINEISIDN-DVIDDIKENERILIDDGKIELKVIDKESKK-IKVEVTRGGILLQRKGVNLPESDIKLSSVTEKDVNDLLFGLENNVDWIALSFVRSENDIIHLRKLIKKNGFDTKIIAKIEKPQAIKNIDKIILNSDGLMVARGDLGVEMPMESVPIIQKKIVYKCNLACKPVIIATQMLESMISQKTPTRAESNDVANAVLDGADAVMLSAESATGNYPLLAVESMNRIINSVEKTSD--TIYFKFEKFKKLKDRVSESLITTACRLSKQISAKAIVTMTKSGYSAFRVSGSRPKARIYIVTNDKKIGNVLNLVWGVRSIYYDK------TENIDITLQNIENLLVKNNHLSKKDKYIITSSMPTWKGHTNMMKVNVV 474
401 0.000e+00UniRef50_A0A212KX63 Pyruvate kinase n=4 Tax=Chlamydiae TaxID=204428 RepID=A0A212KX63_9CHLA  ali  38  4...................RTKIICTIGPAVNSVEKMLELIDAGMNVARLNFSHSNHDGHREVINKLKEA-RDISGKPLAILLDTKGPEVRIGQL-KEETVSLKRGQKLKLKPDQC---GCPEFCVPITPGSVIANIEKGMKVLFNDGHISTHVLSTSEG-SVEVEVENDGDIQSRKGVNIPNAVLGLPAMTEQDIEDIKFGCQEDVDIVAASFIRSPEHVLAIKRLLYDQGKDILVIAKIENTEGVQNFDGILQAADGIMIARGDMGVELPLSDVPPLQKMMIRKCYLEGKPSVTATQMLESMMSNPRPTRAEASDVANAIYDSTSAVMLSGETAAGKYPIETVRVMKQIIRAAEADFDYSIF--SARHSNKVYHDVPSSVTLATVKTAYSSHAKVIFIFTSSGISARLVSRLRPEMPILAMTSRIKSYHQMAFNWGVTPVF-----DNEGVTSMREAFSVLSEYALSQGVVQYGDLVVLTAGTPFGAGTTNMMLVESI 473
402 0.000e+00UniRef50_A0A2D9TGP6 Pyruvate kinase n=7 Tax=Bacteria TaxID=2 RepID=A0A2D9TGP6_9DELT  ali  35  1.................MRRTKIVCTLGPASSSVEVIDQLVAAGMDCARLNFSHGDHAQHAEMARKIREAAGR-ARRPLAILADLCGPKMRVGRFAAG-SVELEEGQAFTLTTEKV---DGDATRVSVSYPALPQDAKVDDTILLDDGLLRLRVTGT-SAKEVQTEVEIGGTLSDRKGLNLPGVELSIPALTKKDREDLRFAVELKVDFVALSFVRRASDIEAAKELAG----GTPIIAKIEKPEAVENLEAILDAADGAMVARGDLGVELGSEKVPLVQKRIIRETNDRGKIVITATQMLDSMIRNPRPTRAEAADVANAVMDGTDAVMLSGETAAGKYPVKAVEMMDLIAREVESEWVQERMTRDMKVVAHEDWEFPEAAARAAAVLSTHLPLAAIVSFTQDGRSAGLLAEFRPRAPIVAITHRAEVAQRLALEWGVVPRL------EVPPEDLDETLRIACALLAREKLAKKGEPFAMIAGWPT-SGRTNTVKLHR. 468
403 0.000e+00UniRef50_A0A1F9E6X8 Pyruvate kinase n=1 Tax=Deltaproteobacteria bacterium RIFCSPHIGHO2_02_FULL_38_15 TaxID=1797857 RepID=A0A1F9E6X8_9DELT  ali  33  1.................MRRVKIVCTLGPATFSNEAIEKLIKTGMNVARLNFSHGDYKTYEKVIRCIREKSEVLK-KPVTILQDLQGPKIRTGKLSQDE-IKIRNGQKITITTREII---GNHEIISIPYRPLPRLLKKGNPILIDDGLIELEVLRT-KNQFIECRVVSGGILKENKGVNIPYIKTQNVSLTTKDKKDLAFGIREGVDFVALSFVRSKQDIIELRKRI-PKSKSIGIIAKIEKREAIDNFDEILSVSDGIMIARGDLAVESSTEIVPCLQKEIIQKCNRALKPVITATQMLDSMVFHSRPTRAEASDVANAVLDGSDALMLSSETASGQYPFKAVSTMDKIIREVEHHDRHQDQRYFIEPHIQGGVVSASRLEKAACQISESIGAKFICCLTEKGRSATLIARCRPRQPIIALTDSPHTMKRLSLVWGVRCYWIKHLFKNR------EVFKTIRNRLLHLKMVKRGDRIVITTGIFTHSPTTHIVKVHQI 473
404 0.000e+00UniRef50_A0A1F3BGX1 Pyruvate kinase n=1 Tax=archaeon RBG_16_50_20 TaxID=1797286 RepID=A0A1F3BGX1_9ARCH  ali  35  4..................NKTKIVCTIGPSTSSRRMIWHLTKAGMNVARLNLSHGTTREHAARIRWIRSVARDLK-SPVGVLCDLPGPKIRVGRLNPD-PVTLNQGGLVILTGRRKM---GSQGILPISHPTVLRTLRKGDSVSLSDGTIRLTIQETRS-SDIVCRVIRGGSLFSGKGLNLPGKNLGLRALTPKDIELLRFALQNHADFLGVSFVTTSNDIDRAKRIVKEAGSRAWVIAKIETRQAVENFDDIVKKANGIMVARGDLGVEMDIEDVPILQKKIIAKANAVGKPVITATQMLESMVTNPTPTRAEVTDIANAIIDGTDAVMLSEETAVGQYPLEAVEVMERVAAATEATLPYREFLEARRPLVKK---VQDAISFSACEVAYELGASCIVAHTRTGTTAHRVSKFRSSVPIIALTYSESVMNRLSLLWGLYPHKVERLST------TREIFSAAKAEARASKIAGRGDRIVVVCGDPSTPGTTDLLRVQSV 471
405 0.000e+00UniRef50_A0A250INM9 Pyruvate kinase n=1 Tax=Melittangium boletus DSM 14713 TaxID=1294270 RepID=A0A250INM9_9DELT  ali  35  1.................MRKAKIICTLGPASDSAQVIEALIRAGMNVARLNFSHGTHEEHRQRVNRIRLASRRL-GMPVALLQDVQGPKIRLGRFAGGLT-EVKAGEQVIVTTRNVL---GQGPLIPTPVRSLPRDVKPGDPILLDDGRVRLRV-ERVEDRDVTCTVEQGGVLKDHKGLNLPGAHVSVPTVTRKDEEDLAFGQELGVDYVALSFVRTAKDIERARKLVASH---TPLIAKIEKPQAVENLEAIARAADGIMVARGDLGVEMPLEKLPGMQKHMVRVVNRLGGLTIVATEMLESMVNNARPTRAEVSDVANAILDGADAVMLSGETAAGKYPVQAAATMARIVEETEGGT---MPVVTEAPFDEARDDISTGVAAAAVAAARQMGIGTIVAYTERGHTARLISEFRPDARIIALTPNAETVNRMALYWGVTARQVGRLQS------TDAMLKQVRRLCREESYCAAGSPVVIVAGVPLNPGGTNMISVHRV 466
406 0.000e+00UniRef50_A0A1V1RI83 Pyruvate kinase n=5 Tax=Bacteria TaxID=2 RepID=A0A1V1RI83_9ACTN  ali  34  27.................MPRTKIVATIGPASEDPSVLRRLIAGGMSVARLNASHGTRVDLERRLAAVREAAED-AGRHVAVMLDLGGPKLRIGE--AEPGVVLERGARFELVAEACV---GDRQRACLTHPEVIADVPPGARVLVDDGRIELHV-EGRDESRLVTVVVTGGPLSSHKGVNVPDVRLSLEAITDKDREDLAWGLSAGVDFVAQSFVRSEADVEALRALMGERA--VPIVAKIEKHEAVERLDAIVEAADALMVARGDLGVETATEQVPLIQRRIVALAREHGKPVIVATQMLESMVSSPRPTRAEASDVANAIFEQADAVMLSAETAVGAYPVEAVEMMTRIAEAAEREVD---ACGAAALPRAARTDVARAVSAAACEIARVLDLAAIVTATQSGATARAVAAHRPKTPIVAATPDERVARRVALVWGVQPLVVPQHGT------IDEMLSHAVEAVRAAGLARPGELVALTAGVAVGPGTTNLVQVTQV 492
407 0.000e+00UniRef50_P94939 Pyruvate kinase n=1098 Tax=Bacteria TaxID=2 RepID=KPYK_MYCIT  ali  35  3..................RRGKIVCTLGPATNSDELILALVEAGMDVARLNFSHGDYADHKAAYERVR-VASDATGRAVGVLADLQGPKIRLGRFATGPTY-WADGETVRITVADC---EGSHDRVSTTYKKLAEDAAVGDRVLVDDGKVCLVVDGI-EGDDVICTVVEGGPVSNNKGISLPGMNVSAPALSEKDIEDLTFALDLGVDLVALSFVRSPADVELVHEVMDRVGRRVPVIAKLEKPEAVDNLETIVLAFDAIMVARGDLGVELPLEEVPLVQKRAIQMARENAKPVIVATQMLDSMIENSRPTRAEASDVANAVLDGADAVMLSGETSVGKYPMAAVRTMSRIICAVE------DNSTAAPPLTHVPRTKRGVISYAARDIGERLDAKALVAFTQSGDTVKRLARLHTPLPLLAFTAWPEVRSQLAMTWGTETFIVPMMTSTGG------MIRQVDKSLLELGRYKRGDLVVIVAGAPPGVGSTNLIHVHRI 467
408 0.000e+00UniRef50_Q22Z06 Pyruvate kinase n=4 Tax=Oligohymenophorea TaxID=6020 RepID=Q22Z06_TETTS  ali  41  22..................RKTKIVCTIGPSCWDHDNLVQLLENGMNVARLNFSHGDHAGHGETVRRLKEAFKARKNIQCALMLDTKGPEIRTGLVKDQTKINLVAGQELEITTD--YSVLGDEKVLACSYKSLPKSVKVGGQVLIADGTLVCIVKEIKQD-SIIVNVQNTCSIGEKKNMNLPGAIVDLPTVTEKDEDDINFGLKHGIDCIALSFARKAEDIEYVRDILGPQGEHIKIIAKIENQEGLHNYEQILDAADGIMVARGDLGMEIPPQKVFVAQKWMIRKALEKGKPIITATQMMESMIKNPRPTRAEASDVANAVLDGTDAVMLSGETANGSFPIQAVQTMAYICSEAELCYDNRQTF-WQRTNNKKKVSAVESMAISAVQMSFEIESPVIIVFTTNGDMARYVSKYRPSAQIFVVSTENGTIKGLCTTFGVRCLRVPSFQG------INKLIDYAVDAAKEQGFIKSGQNAIVILGS............... 481
409 0.000e+00UniRef50_A0A1F2Z709 Pyruvate kinase n=1 Tax=Alphaproteobacteria bacterium RIFCSPHIGHO2_01_FULL_41_14 TaxID=1797217 RepID=A0A1F2Z709_9PROT  ali  32  1...........MHSPQYVKKTKIIATLGPASSTQDMISALALAGVNVFRLNFSHGTHETHAANLKIIREVELKL-GTPLGILADLQGPKFRIGSFEQG-SIHLRGGQKFTLDLGGDL---GTLTRVSFPHAIVYPHLKKDSKILIDDGKIQLKITKVTA-KTIETIVQTGGPLSDHKGVNIPEDRIPSSALTDKDLKDLKFILTQDIDFIGLSFVQHPDDIKTLKKHVKNK---AQIIAKVEKPQAIQYLDEIITVSDSIMVARGDLGVEFPPENVPALQKKIVRLCRLHGKPVIIATQMLESMIKSPIPTRAEASDVATAVYDGADAVMLSAESAVGDHPLEAVQIMAKIIRNVEQDSFYPRLLKATMPI--IENTVSDAITSASQQLVYDLDAKLIITFTATGGTALREAHKRPPCPIVGLTESKSVARNLTLTWGVFPVLLTEKVS-----DFEELTQKALSIVQDYKLAPKGARIVITFGVPFGPGTTNIINVEE. 473
410 0.000e+00UniRef50_B4JRC3 Pyruvate kinase n=8 Tax=Drosophila TaxID=2081351 RepID=B4JRC3_DROGR  ali  46  17.SQLDYKSRLQFNAPTDYALSGIICTIGPATNKPETIVKLIEAGMRVVRLNFSHGTHEYHCRTIQAARKAIDCYTHKPVAIALDTKGPEIRTGQNEGSAIIVLKRGDKIKLTTDKSVENKGNKNMIYVDYEKLSLIIKPENIIYIDDGLISMRVLQVT-GNQIVCEVVNGGKLGSRKGVNLPGTPVDLPSISERDKLDLKFGVEQDVDMIFTSFIRDATAIDEIRKILGTVGKHIKIISKIENQQGLQNIDSIIAASDGVMVARGDLGIEISTEQVVLAQKCIIAKCNKMGKPVICATQMLASMEDNPRPTRSEASDVGNAIFDGADCVMLSGETAKGMYPVECVRCMTDLCSKVESVLWYEQMQNEMKTVVQSSTDNLSAITLGITEIASLSRANAIVIVSPCPLMAQLISQFRPRCPIVFVTGNPRVARQSVLYRGVCPLVPEAMANG--CIDFARILTMSLEQMAKLKIINVDQTL..................... 500
411 0.000e+00UniRef50_Q9WY51 Pyruvate kinase n=14 Tax=Thermotogaceae TaxID=188709 RepID=KPYK_THEMA  ali  35  1.................MRSTKIVCTVGPRTDSYEMIEKMIDLGVNVFRINTSHGDWNEQEQKILKIKDLREK-KKKPVAILIDLAGPKIRTGYLEKE-FVELKEGQIFTLTTKEIL---GNEHIVSVNLSSLPKDVKKGDTILLSDGEIVLEVIETT-DTEVKTVVKVGGKITHRRGVNVPTADLSVESITDRDREFIKLGTLHDVEFFALSFVRKPEDVLKAKEEIRKHGKEIPVISKIETKKALERLEEIIKVSDGIMVARGDLGVEIPIEEVPIVQKEIIKLSKYYSKPVIVATQILESMIENPFPTRAEVTDIANAIFDGADALLLTAETAVGKHPLEAIKVLSKVAKEAEK------KLEFFRTIEYDTSDISEAISHACWQLSESLNAKLIITPTISGSTAVRVSKYNVSQPIVALTPEEKTYYRLSLVRKVIPVLAEKCSQEL------EFIEKGLKKVEEMGLAEKGDLVVLTSGVPGKVGTTNTIRVLKV 465
412 0.000e+00UniRef50_A0A2N2LQU3 Pyruvate kinase n=16 Tax=Chloroflexi TaxID=200795 RepID=A0A2N2LQU3_9CHLR  ali  37  3..................RKAKIVATLGPSTDNEEVLKSLINAGMDVARLNFSHGTYEEHNKRIQMIRKLSDEL-NKPISILQDLQGPKLRVGKLPEGG-ILLIKDQLIALQPLDATEINLTENILPMDVPNLAQAVIPGNRILMDDGNLEIEVNEVI-DTTIICKVILGGRISSHKGVNLPGVDLGIPGFTEKDRSDLEFGLQQGVDAIAISFVCCAGDILEVKEIISPDRIPPPIIAKLERPQAIENLDEILSVAEGVMVARGDLGVEISPASVPIVQKKIIEAAYRHAKLVITATQMLDSMINNPRPTRAEASDVANAILDGTDAVMLSGETAVGKYPLETVMMMDSIVKEAEA--NYKKWSDRGKQPLEPTSDDAVALTRAAGELAADRDVKYIVVLTQTGRTARLMSKVHPNVPILAFTPELSTFRNLNLYRGVNPYLVP------HATNIEDMLAFLEEAIIASTPIQSGQQIIFVSYLPVGERPPNFLLLHTI 481
413 0.000e+00UniRef50_V5C7J8 Pyruvate kinase n=9 Tax=Proteobacteria TaxID=1224 RepID=V5C7J8_9GAMM  ali  32  8.............PPLSSRKTKIIATLGPSSNTAEVIHDLIDAGVNVFRLNMSHGEHEGHRKIYHLIRESANAL-NQHITILADLCGPKIRTGRFNNG-SITLKPGNRVVVTTRDVL---GEDNLIPCQYADLANDVKSGDRILLDDGKLELKVIDKNT-TDVTCEVIYGGELKNNKGINLPGVHVSCPSLTEKDRADALFALALGVDYLALSFVRKAEDIADLRQLIASNGYETHIIAKLEKPEALTNGEEIINAADAIMIARGDLGVELNPEDVPIVQHQLIKRARALNKPVIVATQMLESMIESSRPTRAEATDVSNAVYWAADAVMLSAETAAGKFPVETVAMMVRIINQTEAFMRGQAIFGKTRESELKMLPFGHAVADATAQLCFDLKAKAIVSITKAGMTVITLCSARPEAPLIAISADKRVCQRMNLYWGVIPVYCEDAGLTHPN-------KLARHHALKTGLAVEGDNIILVRGFDQDIKNTPTITILTV 484
414 0.000e+00UniRef50_A0A1E2V209 Pyruvate kinase n=4 Tax=Candidatus Thiodiazotropha endoloripes TaxID=1818881 RepID=A0A1E2V209_9GAMM  ali  39  1.................MRKTKIVATIGPASDRVETLEAMIRAGMSVARLNLSHGSYQEHKQRITRIRQASQNLQ-IPVAIMIDTRGVEIRTGPLQQG-IVELHSGGHFSLYTDDRI---GDEQGVSVTYHRLSQEVGPGDVILLDDGAMELTVDDVAGD-EIRCSVVLGGMLKENKGVNLPNTQLSMTAVETAQRDDILFAAENEVDYIAASFIQQAVEIERMREILAERESKIPIIAKIENRSGIENLESIVSAADGIMVARGDMGVELPLADVPSMQKKIIRITVSNGKPVITATQMLASMEQNPKPTRAEASDVANAILDGSSALMLSGETAMGDYPVESVSTMERLAVRTEASLREYGYLQHILPHASNV--VTEAVSHSAVTMADQLHAAAIISLTESGFTSRLISKHRPECPILAVTHSPRVTRRLCMNWGVIPML------DAADHNDEAKVDYCIEQAKHRGLLTVGDVVIATSGSTQATGGTNLIKVMSV 473
415 0.000e+00UniRef50_A0A2E7GEY4 Pyruvate kinase n=1 Tax=Bdellovibrionaceae bacterium TaxID=2026715 RepID=A0A2E7GEY4_9PROT  ali  34  4..........ELMQESIVRRAKIVCTLGPSTASYEKILEMIHSGLDVARLNFSHGDHPTHQKIFNWVRKASQE-AKRNVAIMQDLQGPKLRLGELK--EPIKAKPGECLFLYPEGKKAVSSHDHLIPMSSDIVSKDASVGDSILFDDGKISTKIQKVAQG-EVLVEVIHGGPLSSHKGMNLPDTPLSFPALSEKDKKDLLFGLEMGVDAVALSFVRSANDIETVRALIQKSSSRPLLVSKIERPEALESYEEIIAVSDVILIARGDMAVEVGAERVPMIQKQLIQECSHLGVPVITATQMLESMIQSPVPTRAEANDVANAVFDGTDAVMLSGETASGEYPIESIRMMSKIICEAEG---YLEDYSVRPPVLPTPGIVVDSIEMSASRIATHLDVVAIACLTHSGMAARALAKYRPEKPIVAIMDQPDTLRKLSFVWGVQGVLIPE------LKPTDDLFSLIEQKLLESNWVKKGDQFVLTAGVPLKRGTTNMIKVQTV 487
416 0.000e+00UniRef50_A0A2R6AEX1 Pyruvate kinase n=11 Tax=Candidatus Marsarchaeota TaxID=1978152 RepID=A0A2R6AEX1_9ARCH  ali  36  5................PLRYTKIVCTIGPATSEENMIVELVKAGMDAARLNFSHGSHSEHLQRLKSLRKISEELK-INISVIQDLPGPKLRVGKLLRE-PLKLEEGSIVKLSNSPFQQ---NDQEIPVLFKNLSKLVEVGSEVYLADGTIRLRVIDI-SKEWVSCRVELGGLLTTGKGINIPKAKGDVSAITEEDIEHIKFGVQNEVDYIAVSFVRSARDILRAKEVLKGFNSDIPVIAKIEKSEAVENIQEIVSSCDAVMVARGDLGVEIGIENVPLVQKKVIKLANLLGKPVITATQILISMLSQPTPTRAEVSDIANAILDGTDALMLSEETAVGKYPLEAVRVLARVAASTEREMVYQ------PKPVIDAESVEEAIGRAACQVANAVKAKFIVAYTRSGSTARLIAKHRPMIPIKAFTPNTKVARRLSIVWGTESFYAQESANAPLPDMVEE-------HLKKLDLVRQGDTVIVVAGMPTGPGSTNMIRVQKI 470
417 0.000e+00UniRef50_A0A2A4PPQ2 Pyruvate kinase n=14 Tax=Bacteroidetes TaxID=976 RepID=A0A2A4PPQ2_9FLAO  ali  34  1.................MNKTKIVATIGPATYDEKILSAIIAEGVNVCRLNFSHGSHEEYLKVIKLVRELN-EXXGRHTAILADLQGPKLRLGDVKNGE-VEILTGDQITLTSEAIV---GDSKRAFVSYPSLAQDVVPGVRILIDDGRVVLKALSTDGKSEVXAEIIQGGLLXPNKGCNFPETKVSMPCLTEKDRTDLRFALEHGVEWIALSFVRSAADIVELKKLIEDENSPAKVIAKIEKPEALEVIDEIIEEADALMVARGDLGVEIPMQDVPIIQKELVRKCRRASKPVIIATQMIESMIDSITPTRAEVNDVANAVMDGADAVMLSAETSLGNHPVEVIKAIHKIVVKSET--FDEIYFHYKLPDPESDRFISDSICFNATKMAERVNATAIVTMSFSGYTGHKISSYRPKASTFVFTANQSILNTLSLIWGVRGFYYDKF------ESTDRTIADIMQELKDGGWIKKGDLIINIASMPIDKARSNMLKLSEV 471
418 0.000e+00UniRef50_A0A1W9RFH5 Pyruvate kinase n=1 Tax=Candidatus Latescibacteria bacterium 4484_7 TaxID=1970771 RepID=A0A1W9RFH5_9BACT  ali  34  13.................MKRAKIVCTIGPASWDREHLSRMIEEGMNVARINFSHGTPDEHRRVFDLIRDLSDR-----VAIMQDLQGPKIRVGGMPEGG-VRLREDAEFILSTRPV---KGDEHVAHVTYPRLNADVEPGDNIYMSDGVIHLVVESV-EGTEVKCRVVHGGTLLSHKGVNLPGVKISTPALTEKDREDLELGLELGVDYVALSFVRSPDEVKELSKIIATHDSHAQVVAKIEKKEALDSIDEIIDAADGIMVARGDLGVEVPTENVPIYQKMIIARCISMGKPVITATQMLESMIHSERPTRAEASDVANAVMDGSDAVMLSEESATGDYPVESVATMRRIIEKVESYLEARQLFSSVFSGQALPFKLVDSICGGAVKVASEVGATAIAVLTHTGLTASILARYRPHVPIVALTDFMPVIRRMSLVWGVDAVPVESI------EDTETIFPIVKKKLAEAGY--RG-KIVVTAGIPTKERPSNTIHLIEI 499
419 0.000e+00UniRef50_A0A1W9HMC9 Pyruvate kinase n=1 Tax=Proteobacteria bacterium SG_bin7 TaxID=1827384 RepID=A0A1W9HMC9_9PROT  ali  33  4.................HRRVKIVATVGPSLSTKESLKLAIEAGLNVVRLNFSHGSHDDHLKTINWVREISKELS-LPIALLQDLQGPKIRVTKFKEGA-IFLSQGQEVFLIPG---LAQGSDHEIGVDFLRLGEAVKPGSKVLLDDGLLELVVTEI-KGDCIHCQVIGGGQLKDRKGINIPGASLPIECLTEKDLKDLEFGLSQNVDYVALSFVRRGDDIEKLREIIDQKKPETRIIAKIEMLEALDNLPTIIELADGVMVARGDLAVEVGQERLPSIQKQLIKLCNHMGKPVITATQMLESMVTKLSPTRAEITDVANAVLDGSDALMLSAETASGKHPARCIKVMSDIIDEVEKSIDYYHTEEDI---AGNFMGFADSISAAACLSARKLNASAIVCLSTSGKTAVRISAYRPKAHIFSASEIADTLNRLSLVWGVRTLKISPYQ------DSEEAFKQIEELMLQAGVVKPGDTVIFTLGMPVKSKKTNSLRIMSI 472
420 0.000e+00UniRef50_B5YJV6 Pyruvate kinase n=9 Tax=Bacteria TaxID=2 RepID=B5YJV6_THEYD  ali  35  1.................MKKAKIVCTIGPSSENREIIRRMIESGMDVARLNFSHGNYEWFENIIKTIRE-EAKNIKKSIAILQDLQGVKIRISDVENEE-IHLNDGMIVEIYSGNEV---SNTNRIFISYPSLIEDVEPGEDILIDDGILKIKVIDKLQDRLI-GQVIEGGILKSRKGINLPFTRTSISSFTEKDKSDLLFGIKMDVDYVAVSFVRNADDIELIKEWANEKNVLPPVIAKIEKREALKKIHEILDVTDGIMVARGDLGVELPAEEVPFYQKMLIDIANQRKKIVITATQMLESMTEHSRPTRAEASDVANAVLDGTDALMLSAETASGKYPVESVKTMSSIISFTEESFS-----DKIATAFKVSKYFPEAIASGAVRVAQDIEAKAIVVFTYSGFSALLISKLRPFMPVVAFTPDEKVYRRLSLLWAVIPMHISKK-----IDMIDNLLKETETELKKLNLVKDGDAVVFVASSPF-LGNRNVVRLHKV 468
421 0.000e+00UniRef50_A0A2H0QWH6 Pyruvate kinase n=13 Tax=Parcubacteria group TaxID=1794811 RepID=A0A2H0QWH6_9BACT  ali  37  4..................KHTKIVATIGPATESKEMLEKLVLAGLNVMRLNFSHGDFAEHQARVDNLRAVSKKL-DRPVAILQDLSGPKIRIGEFDTER-VDLEAGKKISLVTGKKFI--GNETRVWVNYPTLHKELHKGSIVFVDDGKKKLIVESIKKN-EIACKVIVGGNTKGRRGVNLPGAYLKTSSLTKKDREDLQFGIKNDVDFFALSFVRQAKDVVELRDILQQAKSDAQIIAKIETEEAIENLEDIIAVADGIMIARGDLAIEVPAEKVPLYQKRMIELCRQANKPVITATQMLESMINSPVPTRAEVSDVANAIFDGTDAVMLSEETTLGSYPVEAVSVMARVANEVETHG--RAHFKNGHENKMLYDE----LAQSALRIAGAVDAKAIVAITESGSTARALASRRPTQPIIAATGDFKTETRLTLSFGCFPLHTTDKGS------FESVMKQVSLFVKTNKLAKRGDNIVVIFGEPVGKKGTNAVSVQCI 470
422 0.000e+00UniRef50_UPI000299E563 pyruvate kinase n=2 Tax=Thermococcus TaxID=2263 RepID=UPI000299E563  ali  39  7...................KTKIVATIGPASDDSKTLKALIKAGISVARINFSHGTFEEHKKRIERIRRASERL-GRRVPILGDLPGVKIRVGNIIGGK-VELRRNQTVTLTVRDVEGMEG---LIPVEFKDFPKLVSPGDVIYLSDGFIILKVVKV-EGPDVVCKVLAGGVLYSRKGINIPNARIPLEAVTEKDLEILEFMIENDVDAVGISFVGSSYDVLKVRHFIEEKGSRMFVISKIERPDAVRNFDEILSASDGVMVARGDLGVEMPIEKLPILQKKLIEKAVMAGKPAIVATQMLESMTTEKLPTRAEVTDVANAILDGADAVMLSEETAVGKYPVDAVKMMAKIARATEAYRESFGNVREWKEKIPKKGTIKDAIARSIIEALQVVDARYILTPTKSGYTARLISRFRPKQWILAFTSDEKVASGLMFSYGVYPFVIESPDE-----------KEIIQLIKGLGLAKEDDTVLLTEGAPIGKTTTNTVRIFQI 473
423 0.000e+00UniRef50_A0A1Q7UKW5 Pyruvate kinase n=4 Tax=Bacteria TaxID=2 RepID=A0A1Q7UKW5_9ACTN  ali  37  7..................RRTKIVATIGPSCSSPDRLDALVAAGMDAARLNLSHGTHDDHRERATLVREA-QERVGRPIALIGDLQGPKIRVGDLS--APMQLTTGDRITVVMGAD----GEAGELPIAPAAIGEVLRPGHEVLIDDGHVRLQVEEVALGRAL-CGVVVGGPVTSHKGVNLPGVPIPIPSLTRKDLEDLEFALKLGCDFIALSFVRSAADVRDLKALLEQEGSTAHVIAKIEKAEAVDALEDVLAESDAVMVARGDLGVEIGPALVPLVQKRIILEALDRGKPVITATQMLESMIHHPEPTRAEASDVANAILDGTSAVMLSGETAVGEFPVEAVQTMDSIARAVEPSLGYRHQIPEATDDP----TIGNAMSNAACDLAEALGASAILVPTFTGRTASAVARLRPTRPIIGLTHKRWSVQQMAIEWGVTPIWIPE------TKNVEDLWSRSIEAAKTAGFVEPGDTVVITAGTAVNPGSTNVIKV... 468
424 0.000e+00UniRef50_I0AH58 Pyruvate kinase n=29 Tax=root TaxID=1 RepID=I0AH58_IGNAJ  ali  35  7................HIAKTKILATLGPATATVEQIKNLIYAGVDGIRLNFSHGDFNFFEEIFRNIYLACVE-EKTPLAVLIDLQGPKIRIGEL-EEPEIPVKENDTIEITTEKVI---GTKEKISTTYKYLPRDAEVGNLILIDDGLIRLSIIEKTEN-SVICKVLNNGTLKSRKGMNLPGMNLSTPSITEKDYENLEFALKHRVDFIALSFVRSAEDVIELKNWLLMKGKEIPVIAKIEKKEAVEQIDEILKIADGIMIARGDLGVELQPQEVPVLQKSIIRKCNCAGKMVITATQMLESMINSPIPTRAEASDVANAVWDGTDVVMLSGETSVGKFPVRTVQIMNDILKKAEENSFVKKDIDFLIPESLQEK-LFDSVGRAVVSISHQTNAQAIVVFTEKGRTARLISKYRPKAKIIAVSNNFETMNNLSLHWGVIPIFSEKIDKEHIA------IEEAKSSILNSGLAKAGELLIFTAGAPSEKSRTNWIR.... 474
425 0.000e+00UniRef50_A0A0T6BBN4 Pyruvate kinase (Fragment) n=1 Tax=Oryctes borbonicus TaxID=1629725 RepID=A0A0T6BBN4_9SCAR  ali  42  9.NHLRQQANLNIHEKNKLCLSGIVCTIGPASTNANILLDMMKSGMSVARLNFSHGSQSEHTDRIKVIRKALELYKTYPLAIGLDTKGPEIRTGNIMQGSKVEIQAGTYVRLTTDPRYKTMSTNRIIYVDYQRLPQVIKVGDTVYIDDGKIILNCTQIQTD-IIECKVINGGMLGSKKGVNLPGFKLGLPAVSEQDKEDLSWGIRNNIDMVFASFIHTAGDVRDIRNALGPLGKDIWVIAKIETQEAVDNIEQIIEASDGIMIARGDLALQIPIEKVFLAQKSIIAKCNLRGKPVICATQMLESMLDNQRPSRPDVSDISNAILDGADCVMLSGETAVGKYPVECVKTMTKICKEAEAAVWNGRLLQEMLANSSS-LDERNAISAASVVTATLCKASAIILSSGSSELSELISKYKPRCPILAVTKDINFAEKIGLFRGVHPI-ISETGTFSTGLEAQQLLQNVLGYVKSKGFVNNGDRVLFL.................. 495
426 0.000e+00UniRef50_A0A1B1FQR5 Pyruvate kinase n=2 Tax=Flammeovirga TaxID=59739 RepID=A0A1B1FQR5_9BACT  ali  39  5.................INKTKIVATIGPATRDKQKILELIHAGADVFRLNFSHDVHEAHQQVIDWVAEYNSKF-GHNTAILQDLQGPKIRIGEVEGGA-VEIVEGEQIIITNTPVV---GTKDKVSTTYTNIVKDVKAGDNIMIDDGNLCVRVIEV-KGNEIIAEVVHGGKLKSRKGMNLPDTNISEGSLTAKDKRDLEFGLEAGVNWVALSFVRTPQDIMTVKDIIKSKGSDAKIVAKIERPEAITNFDEILKVTDAVMVARGDLGVEIKFEDVPMIQKEIIRKCNKAGKPVIVATQMMESMITNPRPTRAEVNDVANAVTDGADAVMLSAESAAGDYPVETVQAMVRILSAVERQT--QDIYNKTYDFDPAKDSYANLIAQSAAAISKDLEAKCIIGLTQSGFTASRISRHRPDTNIFIFSSDKKLAATLNLVWGVRAFHLLPKESST------ETFKEAEAILVQKGFLAKGDRYVNIAALPLSSGKTNSLKIDIV 475
427 0.000e+00UniRef50_A0A1F3VF09 Pyruvate kinase n=1 Tax=Bdellovibrionales bacterium RIFOXYC1_FULL_37_79 TaxID=1797395 RepID=A0A1F3VF09_9PROT  ali  35  1.................MRLTKIVATIGPASNTDEMIKKLIEAGMNVARLNFSHGTYDDHKQTFNKIRSISRDMK-KHIGILQDLSGPKIRVG-VIKDNGISLAEGDTLILSQNES--DDGTNNRVYIKLQNFHQEVKPGERILLADGLLELEVQDI-DQTDVITKVLDGGLLSSHKGVNLPQTKLSLPSLTQKDKLDLEFGLKLGVDMVALSFVRTPDDIRNLKELIAKAGKDLPVIAKIEKPEALDRINEILFVADGIMIARGDLAIETPLEKVPIIQKELVRKARTAHKLVIVATQMLESMTVEERPTRAEITDVANAVFDGTGAVMLSGETAVGKHPDKVVSQMVKIVKEAEKTAYSPHGDIAPYTDNQ---NIELAAANSSATMANAIKAKAVFALTMSGRSASLLSCQRLGIPVIAFSAQNKTLKKMSILFGVHAVEI------QLFEQLDEVITECVKRAKEENLVVPGDYVVVTAGYPFEEKTTNLVHALKI 470
428 0.000e+00UniRef50_D0MX51 Pyruvate kinase n=30 Tax=Oomycetes TaxID=4762 RepID=D0MX51_PHYIT  ali  38  99............PTTARARKTKIICAIGPASWSVDMLGQLLDAGMNVARLNFSHGDHELHQRSLSNLREAMAARPGCHCAVLLDTKGPEIRSGFLKGHKPVQLKAGQTLEITTD--YGVEGDSSRIACTYEQLPTSVTVGSKILCDDGSLVMTVLECLP-ESIIVRVHNDHLLEEKKNMNLPGAAIQIPGITEKDENDLNFAIPNGVDIVSGSFVRSAANVRAIRECLGEAGRRIRVHAKIESQEALQNIDEIIAEADGIHVSRGDLGMELSPERVFLAQKLIIGKANRAGKPVVTSTQMLQSMTKKIIPSNAECTDVANAVLDGTDAMMLSAETAKGMYPREAVETMAKICVEAEQALDYAEVYRLHRAANSKHVSMYESVASSAVEISLDMGVKLIISITDTGSSTKLLAKYRPKANILAVTFSTLTARQLSVSRGVTALLVESMAG------IEDITLKAIAYAKERGLIESGEIVILVHGLDDTSASTNVVKVIEV 580
429 0.000e+00UniRef50_A0A2C9KZH9 Pyruvate kinase n=3 Tax=Gastropoda TaxID=6448 RepID=A0A2C9KZH9_BIOGL  ali  38  18.SHLQQICSLSVDSQDLVRMTSIICTTGPSCDSVEKLKQLIANGMNICRFNLAHADHEYHLKVLHNLRDAVTASKGTEHSIAIDISGPCTRIGAFKKDRPFKLEKGHILTLTSDESFKEQSDLENIYVP-QSLVQGAALKDQIFIEDGPLCFEVQEK-DDLTLRCLVLHGGEISNFYQCHIPMKPTENPQLTEQDKKDIEFAVEHNVDIIMVSWVWCADIVNAVRQHLGEASSRIKVIAKIENYEGVKRIDEIIEASDGVLVGRGDLGIDIPPEKVFLAQKMIIGRANLAGKPVICAAQMLDSMVTNARPTRAEASDVANAILDGADCVMLSKETAVGKNPIAACGMLSQICTETENALFHARLFKDLRQATVIPTDNVHATSIAAVEAAFRCSASAIIVVTNSGRSATLIARYRPHCIIIAITKSNHTARCLNLHRGIFAVLHTSISCDEWYMDIDMRIHHALSLARKRGYVKPFDRAILVTGQQSGPGSTNTVR.... 517
430 0.000e+00UniRef50_A0A097IU23 Pyruvate kinase n=6 Tax=Stramenopiles TaxID=33634 RepID=A0A097IU23_9PHAE  ali  43  1............................................MNIARFNFSHGDHEGHGACLQRLRQAMSTRRNKHVAVMLDTKGPEIRTGFLADGKKIDLVKGEELELTTD--YDFLGDSSKIACSYKSLPTSVEKGSRILVADGSLVLTVKECKE-TSVVTEILNNCTLGERKNMNLPGAIVDLPTLTEKDINDLQFGVIQGVDFIAASFVRKPEDIDTIRQVLGEEGAHIKIIAKIENQEGIRNYDAILEKTDAIMVARGDMGMEIPPEKVFLAQKYMIRRANIMGKPVVTATQMLESMIKNPRPTRAECTDVANAVLDGTDCVMLSGETANGEYPVDAVSMMSRTCCEAECALNYNNLYQATRNTVVETMEPAESVASSAVKTAIDLKAAMIVVLTETGTTARLIAKYRPDVPILAFTAAPDTARQINGYRNVNTQVIGSMIG------TDSIVFRAVDLGKQNKWVKDGDKVVCVHGMKEAAGSTNSMRVIT. 453
431 0.000e+00UniRef50_A0A1V5R2R6 Pyruvate kinase n=6 Tax=Parcubacteria group TaxID=1794811 RepID=A0A1V5R2R6_9BACT  ali  34  1.................MKRTKIVATIGPASETKKMMESMISAGMNVARLNFSHGTYEHHSKLIANLRSASKK-TGANLALLQDLQGPRIRIGDVAKEG-IEVKAGEEVVLVPGNYSVPLKSANLIPIQYPQLYRDVKVGHQVLIDDAVIELRVKGI-KNKSIRCEVVIGGVIKSHKGMNFPKSVIKCPPVTRKDIKDVEFGVANRVDYIALSFVKNAKDIINLRKYLKENGIHIRIIAKIERREAVKNLKEIIEAADGIMVARGDLGIEMPLEELPLIQKKIIEMCRKASKPVIVATQMLDSMIRNPIPTRAEVSDVANAVLDGTDAIMLSGESATGKYPLKAVQYMSKISREMEK--REILEQEGHEGEYKNNNSITQIISFIAQDLAEDSGARLIVCATTSGFTARNISRFRPGVPIVAVTPSRLTKNQLALSWGVEAHVVP------FTDSFNQLLKHIKQLLVKKKIVKKGDNVVIVAGHPFGKGQSNLIKVEVI 498
432 0.000e+00UniRef50_A0A2A5H2M0 Pyruvate kinase n=2 Tax=Proteobacteria TaxID=1224 RepID=A0A2A5H2M0_9PROT  ali  35  3................RERQTKILATIGPASCSEGMIESLFVAGVDLFRLNFSHGTHAGHQASYDIIRKVEAKYE-HPIGVVADMQGPKLRIGKFEDD-SIALQKGQSFRFDSEDSL---GDESRVYLPHKEVLESMEIGSHIFLDDGKVRIKIIGKGDG-YLEGEVQSGVSLSNHKGFNLPGVILPIPALTDKDHIDLEAALDMGVDWIAQSFVQRPEDVREALDLIKAHNNHVALMVKIEKPSALLQIEEIIDLADGVMLARGDLGVEIPPEDVPSVQKKIVRLARDKGKPVVVATQMLESMIENARPTRAEASDVATAVYDGADCVMLSAETAVGEYPVQAVEMMDRIACRTESDENYLEMMEASRPDALGTAS--DAITAAAYYVAQDVDAKLIVNYTMSGSTAXRTARQRPEMPILCLTPDINVARRLVLSYGVRPVH-----NDVGTDDFVGPARYAAKIALGKGFVKKGDCFVMTAGMPFGAGTTNILRIGEV 475
433 0.000e+00UniRef50_A0A1F2WHN2 Pyruvate kinase n=2 Tax=Actinobacteria bacterium RBG_13_55_18 TaxID=1797197 RepID=A0A1F2WHN2_9ACTN  ali  35  2.................MNKTKIVATLGPACEDIEILEGMIDAGMSVARINASHSDPEEIRSQVGIARKAASNR-GKEIGILLDLKGPKIRVGDIRGGRA-SLDEGQEFELTTR---CVDGDSKRVSISNAEVPEALDRGNVVLLDDGALRLKVLGTTQ-SGVQCKVETGGVLKSHKGVNLPGAKLTLSSLTEKDLAGLDLGIELGVDWIALSFVRSAEDIKILRGILNVKSSSLPIVAKIEKEEAIEDIEAVVRAADAVMVARGDLGVEMPLEKIPILQKKIISVSAEHSKPVITATQMLESMTNNPTPTRAEVTDVANAVFDGSDAVMLSGETAVGRYPIEAVDTMRRIIEWTETSLPYEKWMEKRRKWMTEGD--VEAVCSAACELAIQAKATAIVAATESGFTAEQISQLRPPQPILAATPHEAVARKLSLFWGVCPRLVSMHGS------IEEMFSIAEKVARDEQLLPEGSMAVVTAGIKSNIQTTNTIRCIR. 473
434 0.000e+00UniRef50_A0A0G0U7Q2 Pyruvate kinase n=1 Tax=Parcubacteria group bacterium GW2011_GWA2_40_23 TaxID=1618816 RepID=A0A0G0U7Q2_9BACT  ali  41  1.................MKRTKIVCTIGPASDKPETLKKLIKAGMNVARLNFSHNVLAYHAKVIKNIRQLAQE-SNQPIAIIQDLQGPRIRLGDLPL-VGIELKKNTEVILTTGKR-----NAKKISVTYKNMHLDVKPKQRVLIADGTIELLV-EKVKGQDVICRVVVEGTIFSHKGINLPDTNVRIQLFSDKDKKDLIFGVKQEVDYVALSFVRTAQDVLTLKKMIKAASIDIKVIVKIEKPEAIKNFDAILAVTDAVMIARGDLGIEMSAEDIPVIQKMIINKCLHASKPVIVATQMLDSMINNPRPTRAEASDVANAVIDHTDAVMLSGETASGKYPVEAVETMSRIINKTENSVYDNMVLKEIARFATATDDV---MANVVKKISTKVRPRAIIVATRSGYSARIVSRYRPEVSMWVVSENRKTAQQLNLCWGITSFVLPR------VKDYEELLNQAIQYLKENKKIKAGDKLVVIAG................ 457
435 0.000e+00UniRef50_A0A1F4X8U1 Pyruvate kinase n=1 Tax=candidate division Zixibacteria bacterium RBG_16_50_21 TaxID=1802786 RepID=A0A1F4X8U1_9BACT  ali  37  6..................KKTKVVCTLGPSTDNPKILERMLKAGMDVARLNFSHGNNSEHAARVKSIRQAAKKI-GKVIAILQDLPGPKIRLGKLHK-QQIILKSGQRIYFTSSPPF----SDSRLPLDSPLLVKTIQSGENIYLADGAIRLVVLR-AKNREILAEVQNDGVISSASGVNLPDTNLFGPGFYQSDKPHILFGLKQGVDWIALSFVGSAENLRAVRKICDRHRKGVMLLAKIERQLALQNLDQILAEADGVMVARGDLGIEIPLSQVPLVQKEIIARCNKASKPVIVATQMLESMVNNPRPTRAEATDVANAVLDGADAVMLSAETAVGRFPIQAVEVLSQISLETEKVFPYETYLERAWPSTRLETSF--AIGYAACSTARSIGAKAIVVPTRSGRTALLVAEFRPSQPIVALTRTDLVQRQLALVWNVFPVRNRIWHSLP------AVTQVCRQVVREMGLGRQGDKLVMTSGFPIEPGGTNLIQVV.. 471
436 0.000e+00UniRef50_A0A1E2ZEL6 Pyruvate kinase n=3 Tax=unclassified Gammaproteobacteria TaxID=118884 RepID=A0A1E2ZEL6_9GAMM  ali  39  4...............IPIRKTKIVATIGPASDSVKILEEMIVAGMSVARLNLSHGSYTEHSQRIGLIRQASDNLR-MPVAIMIDTRGVEIRTGKILQG-SVELTSGDTFSIFTD---GRAGDQQGVSVTYQRLHQEVNPGDVILLDDGAMELTVQSIL-DREVRCRVVLGGVLKENKGVNLPNTQLSMAAVEPEHRDDISFAAENDVDYIAASFIQDADEVNRMRKILIEKGVDIPIIAKIENRAGINNLEAIVAASDGVMVARGDMGVELPMADVPSMQKKIIRITVSNGKPVITATQMLASMEHNPKPTRAEASDVANAILDGSSAVMLSGESAMGDYPVESVRTMEMLAIRTEASLREYGYLQHIIPHHSNV--VTEAVSHSAVNMADRLKAAAIISLTETGFTSRLISKHRPECPILAVTQSPRVTRRLCMNWGVVPILFQEESTD------EAKIAFCIEQARKRGLLNSGDIAIATSGYSQTTGGTDLIRVMTV 478
437 0.000e+00UniRef50_UPI000BAA0A0E pyruvate kinase PKLR isoform X1 n=1 Tax=Canis lupus familiaris TaxID=9615 RepID=UPI000BAA0A0E  ali  46  68.TFLEHLCLLDIDSEPAARSTSIIATIGPASHSVERLKEMIKAGMNIARLNFSHGSHEYHAQSIANIREAVESLGYRPVAIALDTKGPEIRTGVLKGGPEVELVKGSWVLVTVDPAFRTLGDAHTVWVDYPNIVKVVPVGGRIFIDDGLISLQVKKIDR-KGLETQVENGGLLGSRKGVNLPGAEVDLPGLSEQDAQDLRFGVEHNVDIVFASFVRKASDVAAIRAALGPEGRTIKIISKIENHEGVKKFDEILEVSDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNLAGKPVVCATQ---------------------------------------------------IAREAEAAVYHRQLFEELRRAAPLSRDPTEVTAIGAVEAAFKCCAAAIIVLTKTGRSAQLLSRYRPRAAVIAVTRSAQAARQAHLCRGVFPLLYSEPPEAIWADDVDRRVQFGIESGKLRGFLRVGDLVIVVTGWRPGSGYTNIMRVLSI 522
438 0.000e+00UniRef50_A0A0S3QUS1 Pyruvate kinase n=1 Tax=Thermosulfidibacter takaii (strain DSM 17441 / JCM 13301 / NBRC 103674 / ABI70S6) TaxID=1298851 RepID=A0A  ali  36  1.................MRRTKIVATVGPSSQEIDTLVKLIEAGVDVFRLNFSHGDQEYHRQNIEKIRKAS-QIIGKPVAILQDLSGPKIRVTYIKDG-SIDLHHGDIIKL----NKTSEIDEEAISISHPEILEKLHPGNFISMADGTIRLKVV-KTDAEYVYCEVLNGGVLSLRKGVNFPDIDLDIPAITEKDVDDIKFGVQQGVDIVAVSFVRDHVDVLMAKKYVKSFGGDQPVFAKIERSEAVRNVDDIIQAADGLMVARGDLGVEIDIEKIPVLQKQMIGKCIDHGKPVITATQMLTSMINSPFPTRADVSDIANAVLDGTDAVMLSDETTIGQYPVEAVEMMARVVKEAETMYSFFRKPPRLTKEA--------ALSYSAVILARDIDADGMAVFTCTGRSALRVARYRPKCPIYACTTSEKVLRRLSVIWGVIPFAVLKMY-----EDSKAMVDEFIDLAKSRGVLQEGHKFIAVLGTHFHSKGTNTV..... 459
439 0.000e+00UniRef50_A0A1J4JBU8 Pyruvate kinase n=1 Tax=Tritrichomonas foetus TaxID=1144522 RepID=A0A1J4JBU8_9EUKA  ali  36  1.................MRKTKIICTLGPASESPEIIKALVEAGMNVARFNMSHGSHEDHARRMSTVRSVAKSL-NVSVGILLDTKGPEVRVKSFKGGK-VQIKDGQAFTFTGDEV---EGDNTKVSVTYKQLYEDMKKGDKIMVNDGLVKFEVVDV-KGHDVLCKCLQGGFISNSKSMNFPNKVLSMPFISDVDREDIIFGAKQQVDFIAASFVSNKMNVVELRQLLNHHGGDIEIIAKIENQSGVNNIEDIYTVADGCMVARGDMGVEIEFARLPIIQRRIVKIARNLGKRVIVATEMLESMIEHPRPTRAETSDVATAVSQGVSAVMLSGETAAGKYPVECVKAMSEIALEAENQISY---FSELTHNVFKIDNMAEAVCHAAVDAALALNVRMIIVFTKSGRSAKNVSRFRPGMPIVAATSDELTFPRLSLCWGTIPNLVQDYHKS------EDLYKQAEDIARNNGCV-DGDTVVVTSGLPLNQG-TNIMKIMT. 466
440 0.000e+00UniRef50_A0A2G6G963 Pyruvate kinase n=1 Tax=Candidatus Campbellbacteria bacterium TaxID=2026716 RepID=A0A2G6G963_9BACT  ali  39  2...............KKLKKTRIIATIGPATNNPDILAKLSKEGMNVARVNFSHEKGKSAKPIFENIKRAEKK-SQKTISILQDLGGPKIRTGEFENGETV-LKKNSTVKIYTKKVL---GNNKEFTINYKNLFKDLKKGQRILLNDGKQELKVTKVSKD-SLEAKVVYGGFVRSKRGVNLPDSELSISSLTKKDKLDLEFGLKMGVDFVALSFVKTPKDIIDLRKILNKHKSKAMIVSKIETPQAIANFDQILEYTDAVMVARGDLAVEVGPERVPMLQKEMIRKCNAVGKPVIVATQMLESMIKSPVATRAEVSDVSNAILDGADAVMLSEETAMGQYPLETLKVMRKVAQEVESKFRYDKFLTREYFSDSLSLSKTNSVSRYAAKTASDIGAKNIVVFSETGATSRMVARFKPEQNIVLITPNKETARQSQITFGVH------YRGFYFCKSVEGAINASRKVLLEKKIAKKGEKVVLVVGLPFGVGSSNTISVFEV 476
441 0.000e+00UniRef50_A0A2N6BTN8 Pyruvate kinase n=2 Tax=Deltaproteobacteria bacterium TaxID=2026735 RepID=A0A2N6BTN8_9DELT  ali  37  7..................RRAKIVCTIGPATRSEEMLKRLIEAGMDVCRLNMSHGTHEEHGEVIKRIRKVSAE-TGKQVAILMDLSGPKIRLGELP--APRLLHVGDEVWFTTNIKAPLEGD---VPVKYPQFTSEVKVGERFSLVDGLIHMECLEVSGDR-LRARVNHGGTLSSSKGVNLPTGGEGLPSLTEKDAVDLRFGLKAGVDWVSLSFVRSPSDAGPPRKIMDEEGRRVPLMAKIEKPQALINLDAIVKAFDGLMVARGDLGVEVPLERLPMIQKEIISRANRVGKPVVTATQMLLTMVGNPTPSRAETTDVANAMMDGTDAVMLSEETAMGSYPVEAVRMMNRI---GEEVANSGIATPTIIPSPPGNMTPTEAIAKATRSVALEIGAKAIVIPTTSGATARHIAATRPEQPILALSTLHDTVHQLGVSWGVTAMEISP------QDSTDAVFERCRQAALETGLAERGDLVVVTAGHPLHAGNTNILKVMRV 473
442 0.000e+00UniRef50_A0A2N1VM57 Pyruvate kinase n=4 Tax=Bacteria TaxID=2 RepID=A0A2N1VM57_9BACT  ali  34  2................NLRKTKIVCTIGPASSDINVLVKMIETGMDVARLNFSHGTHEQHNELINTIRQAS-EIAGKKIAILQDLQGPKIRTEQVENGC-VILKDGDEFTITTDNI--GFGTSQIVSTSYKDLPTDLHKGATLLLDDGYLILKVNSIQ-GNNIITTVIKGGELRNNKGIIAPGISFSAPSLSEKDLEDLKFGLSSDIDVVALSFVRSVRDILELKTTMKIFGRIVPIIAKIERPDAVLDIDNIIAEVDAIMVARGDLGLEMLPEQVPIIQKELIRKCNHYGKPVITATQMLESMIKNPRPSRAEASDVANAVIDGTDCVMLSGETSVGRYPIEAIDYMSKIIENVENKYYTKEYGYSIFEAYTTEMS--DSLGKAACIIADEINAVAIVTFTSSTATAKNVAKYRPRVPIIGLTDDLHVHRRLNFVWGVKSVLVQAAENELLIPDSY------IEDLLKLDFIKPDDNLVFVSGSRGNIREQNMIKIFKV 473
443 0.000e+00UniRef50_A0A088TLM6 Pyruvate kinase n=3 Tax=Terrabacteria group TaxID=1783272 RepID=A0A088TLM6_9BACT  ali  38  2...............IPFNQTKIICTIGPASDSFEIMKALVEAGMDVMRMNFSHGTHQDHYEKLMTLDKINEEL-GTHIAALLDTKGPEIRTHLFKDGKA-TVAEGAKVIIHMDEV---EGDSTHFSISYPNLYKDMKVGQTILVDDGYLALKVEKIDANKLIHTIAENGHILKNRKGINVPGVKLNLDFISPKDYADIVWGCENNVDFIAASFVRRASDVQEIRNIIKYNGKEIQIISKIENIEGVENIDEIIEISDGIMIARGDLGVEVPAEDVPVIQKSIINKCLAKGKISVTATQMLESMIEHPRPTRAEVSDVANAIYDGTDAIMLSGESAVGNYPVESVETMNRIANRIEAQIDRKDIVKRANKQNDSSRRIATSIAISVAYTVIQSKVNLIIVPTVSGRTAKYLSQFRPNARILALTSSDKYAKGLQLHSGVEPIEV------HLVKDVETVVAEAIKIAKRDYGIKKGDRVIITGGFPIGE-PTNGMRIVDI 476
444 0.000e+00UniRef50_A0A0K2GA77 Pyruvate kinase n=30 Tax=Bacteria TaxID=2 RepID=A0A0K2GA77_NITMO  ali  35  1.................MRKVKIVCTIGPASESLGQLDRLIDSGMDAARLNFSHGTHGSHAAAIKA-VRRAADRRAAAVAIIQDLQGPRIRVGELPA-RTMALETGRSVRLTPEPAPDRGCGGIDIPITYPHLARDLESGARILIDDGLIELQATRIASG-CVECIVLTGGTITSHKGINLPGTRLRAPALTDKDRADIQFGIAQGVDYVALSFVGDGADVVAAKRLIADCGAEVPIIAKIERAEAVAGLDEILEEADGVMIARGDLGVEMGPEAVPLLQKRIIAEANRRRRLVITATQMLESMTHHPRPTRAEASDVANAIFDGTDAVMLSAETAVGRYPVETVQVMDRIIRAAEEGSERGVVHR--RQVDAGDMSLPEAICTAASSAAGAISASAIVAFSELGRTARLISKQRPAAPIIAFTPFESVRRRMALYWGVRP------QTMQQIAQTDERIDEAERRLKSEGLVKPGERIVILSGTRIGPGGTNLVKLQEV 481
445 0.000e+00UniRef50_D0NBJ9 Pyruvate kinase n=18 Tax=Oomycetes TaxID=4762 RepID=D0NBJ9_PHYIT  ali  42  26..................RKTRIFCTLGPSCWTEEGLGELIDAGMNVARFNFSHGDHGSHAETLNRLRAALASRPHKNIAIMLDTKGPEIRTGFLANKDKITIKKGSTVELTTD--YEFLGDETKIACSYPELPQSVKVGGSILVADGSLVLTVTEIKEDG-VVTRANNSATLGERKNMNLPGCKVMLPTLTEKDEDDLNFGLVHGVDYIAASFVRTGQDIDNIRQVLGPRGRAIKIIAKIESQEGLENFDEILVKTDGIMVARGDLGMEIPPEKVFLAQKMMIRKANIAGKPVVTATQMLESMIKAPRPTRAECTDVANAVLDGTDAVMLSGETANGDYPTEAVQMMSKICVQAEGAIHYNELYQALHNSVLDTMDTQEAITSSAVKTAIDINAKMIVVLTESGNTS--------------ASALGGTARQAGFNKGVTARCMGSMIG------TDSILFRATDLGKQFGWVKPGDNVVALHGMVARSGST........ 482
446 0.000e+00UniRef50_A0A2D7HMG4 Pyruvate kinase n=5 Tax=unclassified Alphaproteobacteria TaxID=82117 RepID=A0A2D7HMG4_9PROT  ali  34  1...........MSNTNFFRSTKIVATIGTATDDYENIKSLIKAGVNVFRLNFSHGNHGDHLKRITYIRGAEKEL-NINVAILADLQGPKFRIGEMKKD--IKVIKGNNFTFDKDTKI---GDFNRVYLSHEEIFESLSVGSKILMDDGKLQFEVKKIT-NEKIQTEVLVGGTVKSNKGVNLPDVVINTNPLTEKDLDDLKFILNQEIDWIALSFVQKLSDVEEVKKHIKDK---ALVIAKIEKPSALKELSQIVDACDGIMVARGDLGVELPPEKVPGIQKEIILECRQAGKPVIVATQMLESMIESPAPTRAEASDVATAVFDGADAVMLSAETAIGSFPIETVNIMDRIISSAERHIH--KHPGDGPQGLVAESFVYNAVSRSAVSLAESVKAKAVVAFTASGNTAYRMARERPNLLLVVMTPEVNVKRKLSLLWGAYPFLSKVQG-------YEAAIQEAREIITKEKLAAKGDSIVVVAGMPFGSGSTNSIRVVEI 471
447 0.000e+00UniRef50_A0A2V7ULH8 Pyruvate kinase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V7ULH8_9BACT  ali  34  3.....................KIVATLGPASEGSEILSNLVLTGVDVFRLNLSHGTREEHRRRIRLVRRLAARHS-RQIGILVDLPGPKIRTGNLVGHLPVTLPAGSRVTLTTRSILGRPG---LISTGYRHLPRDVRKGSRVLLDDGNMELEVLRV-AGTEILCRVVVGGTLSEHKGINLPGTPVAASSPTSKDRQDLEFAVREQADWIALSFVKRPQDLIRARRAM-SRGRQLPLVAKIERREGVEALEGILSQADGVMVARGDLAVEISPEEVPVLQKKMIRGANLSGVIVITATQMLESMMESPRPTRAEASDVANAVFDGSDAVMLSGETASGNFPVESVRMMDAIIRQAEASGLGRG--PEGEGGCCAPDEDLHAVVHAASQAALDARARAVAVYTQTGRTARFLSKLRPPCPFIALTFDRAVARQMALYWGVTPVLI------HFASDTDTMLAGGEKEMLRHGLISRGDRIVVVAGSTSFPGGTNMMKIHGV 467
448 0.000e+00UniRef50_A0A2B7GRU7 Pyruvate kinase n=9 Tax=Natrialbaceae TaxID=1644061 RepID=A0A2B7GRU7_9EURY  ali  36  1.................MRNAKIVCTLGPASNDRETIRDLAAAGMSVARLNASHGSPEDRADLIDRVRAVDEERTE-PVAVMLDTKGPEIRTAPLPDGETVSLETGAEIRFVEGEEATSNVVGLSVSID------AVEPGDRILLDDGLIETTVRETRGDHEVRARVDTGGELGGRKGVNVPGVELDLDVVTEKDRRDLELAAEKGVDFVAASFVRDADDVYEVGEVLEEAGTDIPIIAKIERAGAVENLDEIIDAAYGVMVARGDLGVECPMEDVPMIQKRIIRRCREAGRPVITATEMLDSMVHARRPTRAEASDVANAVLDGTDAVMLSAETAVGDHPVAVVDAMDSIVREVEGSGEYAELLEQRVPASGDAR--TDALARSARFLARDIGADAVVAATESGYTALKTAKYRPGVPVVASTPSQSVRRQLALSWGVTPLYAHVSDQGA-----DAVVEKAVQAALDAGVAESGDTVVVLCGMMTGANTTNMLKVHV. 476
449 0.000e+00UniRef50_A0A2N2WAC9 Pyruvate kinase n=1 Tax=Bacteroidetes bacterium HGW-Bacteroidetes-6 TaxID=2013696 RepID=A0A2N2WAC9_9BACT  ali  34  2.............SPITFNRTKIIATIGPACLSEDKLKELAEAGMDVCRLNFSHGEYEQVAAIVENVIKINNE-SGYSISLMADLQGPKLRVGNMSDHG-VMLNVGEKVIITNEEVF---GTEACFTLRYPLLSQDLKPGERILLDDGKMEVEIGAILSEKEVEAFVIRGGVLKSKKGFNLPGSNVSLPALTEKDLADLQFALSLDVDWVALSFVRRAADVQELKDIIAASGKTARVIAKIEKPEAVSNIDTIIDVADAIMIARGDLGIEMPLQEVPVLQKNIIQKCIAAAKPVIVATQMMESMMESTIPSRAEVTDVANAVIDGADAVMLSGETSVGKYPVLTVATMDKIITDVER--DSRPYIRGTQPKCCGHTFVSDEICYTATRMSAHMSAKGIVVMTQSGSSALRVSSYRPKSPVFVFSENSKLLRTLNLAWGIRGFHYDNYAS------TDQSITDTIEILKSGNIVNKGDVLIHTASMPIGKRRANALKVSVV 476
450 0.000e+00UniRef50_A0A0B1ZPA1 Pyruvate kinase n=4 Tax=Novosphingobium TaxID=165696 RepID=A0A0B1ZPA1_9SPHN  ali  36  16...............KRTRKVKILATLGPASRDRETITRLLKAGADAFRVNMSHGDHDTHRETIANIRAVEKDLM-RPVAVLCDLQGPKLRVGTFRDGKAF-IRHGAHFTLDSDP---TPGDDTRVQLPHPELFGLLEKGQRLLIDDGKLRFVVI-KPEKDRILCSAEVGGQISDRKGVNIPDAIVPVPALTEKDRRDLAFAVKEGADWIGLSFVQRPEDVAEARRLMGGYGA---LMAKIEKPAAVQSLDEIIELSDGIMVARGDLGVELLPEEVPPIQKHIIEKTRAYGKPVVVATQMLESMITSPTPTRAEVSDVANAVYDGADAVMLSAETAAGQWPVEAVTIMDRIATQVEGDKTYRERIH--IAATPPDATTADALSASCATIADTLPIEGIIIFTGSGISARRVARERPSAPMLVLTPSQKTARRMALLWGAHNV------STKDIGSFEEMIAKGKRMALRHGFGAAGSRLVALAGVPFGPGSTNLLHVVT. 483
451 0.000e+00UniRef50_F6G6D4 Pyruvate kinase n=90 Tax=Bacteria TaxID=2 RepID=F6G6D4_RALS8  ali  32  39................RFRSTKILATLGPASSDEATIRALFDAGADVFRLNFSHGSHDDHRKRCDAVRAVEAQ-TGRPIGILADLQGPKLRIGTFAGGR-VALTGGERFVLDRDP---TPGDAARVHLPHPELFAAAAPGQSLLLDDGKIRLAV-EAAGPGAIVTRVVDGGPLSDRKGVNVPDAVIPIPALTEKDLRDLDFALSLGVDWIALSFVQRAEDVRAARARIGERAG---LLAKIEKPAALLHLEDIVQAADALIVARGDLGVELPPERVPGVQKRILRVARQHGKPVVVATQMLESMIEAPVPTRAEASDVATAVYDGTDAVMLSAESASGKHPVAAVGIMSRIIAETERDPLYRNLIDAQHQVPLPTR--QDAICAALRDVTHILGAVATVTYTSSGKTSLRAARERPLAPIVSITPRLDTARRLALAWGVHSTVSPD------VGNVDEMVEAACRAAGREGFAVAGDPIAITAGMPFGAGTTNLLRLAEI 506
452 0.000e+00UniRef50_A0A250BRR1 Pyruvate kinase n=11 Tax=Bacteria TaxID=2 RepID=A0A250BRR1_MYCLP  ali  35  165..................RRGKIVCTLGPATNSDELILALVEAGMDVARLNFSHGDYADHKAAYERVR-VASDATGRAVGVLADLQGPKIRLGRFATGPTY-WADGETVRITVADC---EGSHDRVSTTYKQLAQDAAGGDRVLVDDGKVGLVVDGI-EGDDVICTVVEGGPVSNNKGISLPGMNVSAPALSDKDIEDLTFALELGVDLVALSFVRSPSDVELVHEVMDRVGRRVPVIAKLEKPEAVDNLEAIVLAFDAIMVARGDLGVELPLEEVPLVQKRAIQMARENAKPVIVATQMLDSMIENSRPTRAEASDVANAVLDGADAVMLSGETSVGKYPLAAVRTMARIICAVE------DNSTAAPPLTHVPRTKRGVISYAARDIGERLDSKALVAFTQSGDTVKRLARLHTPLPLLAFTAWPEVRSQLAMTWGTETFIVPMMTS------TDGMIRQVDKSLLELGRYRRGDLVVIVAGAPPGVGSTNLIHVHRI 629
453 0.000e+00UniRef50_A0A1L4D1U3 Pyruvate kinase n=1 Tax=Silvanigrella aquatica TaxID=1915309 RepID=A0A1L4D1U3_9PROT  ali  35  4...............NNLPRTKIVCTIGPSSSTKEMIVKLIDAGMNVARLNFSHGDHAVHAANISLIREISKE-KNIQVAILQDLQGPKIRTGKLINGG-MTLTRGQRLTL---RYAAEQTSNEFLPIDYRELASDVKVGARILLDDGLLSMKIIDIR-GSDVDCEVTHGGFLKSRKGVNFPECHLSIPATTEKDIRDLLFGVAQGVDYVALSFVQTPADVAKLKMMLRALGADTPVITKVEMLSAVHHIDEICDVSDGIMVARGDLGVECGFANVAAYQKKIIESALNHGKPVIVATQMLDSMIEHRRPTKAEVCDVANAVFDHADATMLSGESASGKYPELAVATMRNILDRVDKSKSITP-FEPTPLSKMSAETSAEVFARTTVELAEKMKATAIICLTLTGSMARYVAKYRPQTPIIAFSPRPDVVRKLCLVRGVIGVL------NNIFYDTDTAFSEIAKYLAKEGYVKEGDLVLITGGIPVSQLPTNTLKIHRV 476
454 0.000e+00UniRef50_A0A0F9P282 Uncharacterized protein n=1 Tax=marine sediment metagenome TaxID=412755 RepID=A0A0F9P282_9ZZZZ  ali  32  4................HMRRTKIIATVGPASNDAKTLKQLINEGVDVFRFNLSHSTHAQHKKTLAAIRKVSKEL-NTDVGILFDLAGQKLRIGNMK--KPVEIKRGQEITLTKNKVM---GTGSRISVNHNYLIKELSKGDKILIDEGRIELKIKRKTPA-ELICTVKQGGVLSSNKGINV-TAPLSLKPLTKKDREDIKFAIENKVDWLALSFVRHKSDISDLKAFIKRNKAHFAVMAKIEKKEAVSNIDEIIEASDGIMIARGDLGVEMPVEDVPLIQKTIIEKCMQKGKAVVTATQMLESMINNRRPTRAEVNDIANAIFDQSDAVMLSAETAAGKYPVAAVKTMAKVAGKTESAIDYAWMLRD--KEAWVSADITDAISFASCELVRDLGAALLVTSTQSGATAARVAAYRPPAPILAATPDKRVMNRLKLIFGVVPYLI------NPSKNINDMLAKAKQAAKQSSLVRKNDKIVITAGALVNVGTTNLIKVETI 472
455 0.000e+00UniRef50_R5VVI3 Pyruvate kinase n=1 Tax=Corallococcus sp. CAG:1435 TaxID=1262867 RepID=R5VVI3_9DELT  ali  37  1.................MRKTKIVCTLGPASTTYDQIKKMALAGMNVARINMSHGTYEEHQQRVDNVKKVRRNL-GVPIPIMVDTKGPEVRIGTFRDGK-IEVKEGMPFDFVAEDVV---GDETKVSITYKELYKDIRENGTILLNDGLLMFRITGI-DGTTIHTEAQNSGTLSDRKGLFVPNAKLNMPFLSEQDKKDLEYGIKIGAEMYALSFVQDGDCVREVRKFMIDHGKDVCLISKIESQSGLDNIDDIISASDGVMVARGDLGVETPYEKLPAIQKMLITKSRMSGKFVITATEMLESMITKLRPTRAEIVDVANAVYDGSSCVMLSAESAVGINPSNTIATMARIAEEAERNIDYKQMY---TASPFTLMNNTDAISHATVNTAFDINAKAIVVYTARGASARMVSRFRPGAPIVAMTNSDRVYNQLATSWGVIPVIC------QTFDNTDDMFINAEEVVKRLGLAKAGDNIVITAGVPLGKNGTNLIKVGSV 470
456 0.000e+00UniRef50_A0A2A5EGF4 Pyruvate kinase n=3 Tax=Bacteroidetes TaxID=976 RepID=A0A2A5EGF4_9BACT  ali  34  1...........MKKNIKYNKTKIIATIGPATSSVSMLKKIIEAGVDVCRVNFSHGDWETHLQVVKNIRQANEEL-GTKVAILGDLQGPKLRIGEV-EGNRMLLEDGATMTLTTQATI---SSGNTIYVKYSTLARDVKVGERVLLDDGKLELEFSKRIDAHTVEARVINGGYLSSNKGFNLPSSDMSVASLTEKDRKDLEFVMEHDFDWVALSFVRAAKDIEELRKILDENQCDAHIIAKIEKPQAVDNIDSIIEVTDAIMVARGDLGVEMPMEQVPMIQKRIVTKCVEASKPVIIATQMMESMITSPTPTRAEANDVANAVMDGADAVMLSAETSVGEYPLKAVEAVEKILGSTELGWNVYNKFK--KPDPSSPSFISDRICYATVSMSEGIKAKAILSMTQTGYTAYKIASGRPNCDVFIFTSNKRLLTRLSLVWNVRAYFYDSKT------NTDDTVKDVIKILKGEGFLVDGDVVINTAAMPIENRKTNTLKISTV 477
457 0.000e+00UniRef50_A0A0T6ALN9 Pyruvate kinase n=2 Tax=unclassified Armatimonadetes TaxID=1042316 RepID=A0A0T6ALN9_9BACT  ali  34  3.................IRQTKIVCTLGPATTGRDVLRGLLDAGMDAARFNLSYGTHEEHARTLALLRDLAGEM-GRQVAVLFDLPGPKLRTGPLPGGA-VDLRVGDTVRLVPDPSPAARAGEPVVPYRYPALSRDVRPGNRAFLQDGEIALQVQEIV-GEEVICTVLNGGRLRQHAGINLPGVQLSVPAVTAEDFRHLEFGLAQGADYVALSFVEGPDEIRGVREFVEQRGGAVRLVAKIERRRALESIDEIVAAADAIMVARGDLAVETSPEEVPIIQKALIATCNRRGVPVITATQMLESMVQNPRPTRAEAADVANAVFDGTDALMLSGETAIGRFPVEAITAMARIAERAEAALPYDLILRE--RARTVERSTAEAIALASVQAAETLGAAVIVAATTTGSTALRVARFRPHRPILALTMSEATLRRLRLVWGVHPVVMPEVR------DFDEVIAAAQDAARRTGLARPGDDIVVTAGYPMGSGTTNLLKVVRV 477
458 0.000e+00UniRef50_A0A136KZ73 Pyruvate kinase n=8 Tax=Chloroflexi TaxID=200795 RepID=A0A136KZ73_9CHLR  ali  34  1.................MRNAKIVATIGPASGSEEMLEKIIKAGMNVARLNFSHGTHDQHAKGVSLIREVSKRLK-MPVGILQDLQGPKIRVGKL--DTPMQLSIGEEVCLYATNDQKPDTNCQLIPVDFREIFESVQVDDKLLLDDGRVALQVIS-ARGREVHAKVLVGGILSSHKGINLPGVKLRIAGFTEKDRADLAFGISQNVDAVAISFVRSAEDVKTVRAAIKEFSREPMLIAKLEKPEALQELDAILDVVDGVMVARGDLGVELPPEQVPSLQKRIIQKANAKTKLVITATQMLESMTENPIPTRAEASDVANAIFDGTDAVMLSAETASGKYPVEAVSIMSRIVVEAESHYKEWGNEQDTNRTGLERND-AASMARAANTLASDDDVEAIAVFTMRGSSAWLMAKARPPKRILGFTPDEATLNQLAFLWGVQPYLVG------YASTLDDMISDVDSVLLTSGIA-SGHQVVLICGYPIGQRPPNMALLHKV 475
459 0.000e+00UniRef50_A0A258VQK9 Pyruvate kinase n=1 Tax=Bdellovibrio sp. 28-41-41 TaxID=1970323 RepID=A0A258VQK9_9PROT  ali  33  6..................RKAKIVATLGPSTSTKETIKQAIESGMNVARLNFSHGNHEGHLKNIEYIRALSQEL-NAPVAILQDLQGPKIRVGRFPNG-SIVLKVGDVIEMTPESV---EGTEKLIPCDLKELLSIVSVGFKVLLDDGLIEL-VIEKIKETSVVLRVIYGGLLKDRKGINIPEAKLPIKSLTEKDLIDLKFGLKNNVDYVALSFVRHGRDIRYLRELIELENSEAKIVAKIEMLEALENLDEIIRLSDAVMVARGDLAVEVGQTRLPGIQKKIITMCNDMNKPVITATQMLDSMVENPRPTRAEITDVANAVLDGTDALMLSAESASGKYPFKTIQTMHEIIAEVEK----NEEKYYRISLENEFLSIPSSIGASACLSALKLNAKAIVCLTTSGKTAQIISGFRPQVPIYAMTSQLEVLNRLELTWGLQTLKID------HYKSLMDILARLDNVMVSYGLAKPGDRVILTLGQPVDSGSTNALYVH.. 470
460 0.000e+00UniRef50_A0A158S3K2 Pyruvate kinase n=60 Tax=Bacteria TaxID=2 RepID=A0A158S3K2_9SPHN  ali  35  16...............KRARKVKILATLGPASRDKETIAKLLRAGADAFRVNMSHGDHETHRETIANIRAVEKDLM-RPVAVLCDLQGPKLRVGQFEGGKAF-IRHGAHFTLDRNP---EPGNDDRVCLPHPELFGLLQKGQRLLIDDGKLRLVVIR-AEPDAILCSAEVGGPISDRKGVNIPDAIVPVPALTEKDRRDLAFAVQEGADWIGLSFVQRPEDVAEARRLMGGHGA---LMAKIEKPAAVESLNEIIELSDGIMVARGDLGVELNPEEVPPIQKRIIEMTRGHGKPVVVATQMLESMITSPSPTRAEVSDVANAVYDGADAVMLSAETAAGQWPVEAVTIMDRIASQVEGDSTYNARVH--LAQTPPDATTADALSASCATIADTLPIEGIIVFTGSGGSARRVARERPAAPMLVLTPSQKTARRLALLWGAHTV------STRDIGSFEEMIAKGKRMALRHGFGAGGSRLVTLAGVPFGPGSTNLLHVVT. 483
461 0.000e+00UniRef50_A0A2N1PUW3 Pyruvate kinase n=1 Tax=Candidatus Wallbacteria bacterium HGW-Wallbacteria-1 TaxID=2013854 RepID=A0A2N1PUW3_9BACT  ali  33  2...............NSFRKTKIVCTLGPASSSPEMVEKLIDAGMNVARLNFSHGSHSDHTRMFNLIRKTSEK-KGVYIGILQDLQGPKIRIGKVCNQGGLPLEPGHQIAISVDPALAD--NHSILSTTYPNLANDLKPSDRLLLDDGRLELSVDSI-EGPIIRTTVVTGGILKSSKGINLPGVMVSATSPTPRDMDDLILGLELGVDFVALSFVRTPDEILSVKREIHRRGLRTRVIAKIERPEAMDNLEAIMEVSDGIMVARGDLGVEMGPHMVPPLQKKILKRAAYHGKFVITATQMLESMISAPTPTRAEASDVANAVLDGSSAVMLSAETASGSYPVETVKMMKKIIMEVEPLVEPIRGHCFSPGLMQE-----NAVSSSAVNAAELLGARAIVAFTQTGATALSISKYRSTVPVIGASPSRETLRRASIYWGVEPMEVPVAP------DTDTMSSILEEHLLSDSRFRAGDLVILTAGTPFRPGTTNMMKIVR. 473
462 0.000e+00UniRef50_W6M8L9 Pyruvate kinase n=9 Tax=Bacteria TaxID=2 RepID=W6M8L9_9GAMM  ali  33  5.................VKFTKIVATLGPNSRNPDVVEGLLQEGADVIRLNFSHGTHDDHALSVRLVREAAQKLH-RYIAIFQDLQGPKIRLGQIQ-GEFLEVATGERLVLTTDDLVGGLYDNKKIAIDHRTLHEEVKPGDRILIDDGLFELTV-ERIEGHEIFTQVVNGGRLKPRKGVNLPNIKLKISAVTEKDRADLQFAYDHGLDYVALSFVRDAEDVKELIDFLTNYGRKIPIIAKIEKPEAFQHIDGIINVVDAIMVARGDLGVETSPQDVPLMQKTIIRLCNLAGKPVITATQMLESMINNPRPTRAEANDVANAILDGTDAVMLSGETAAGQYPVAAVRMMKNIALSVEASLMHKSVLTHEELMSKVALRVEDAVHFATVDLVEKVRATYLVGFTNSGASVLGLAKFRPVAPLIAFSSKLGTLRKLALVWGVTPLQLGSVVT-----SVNDLLTAATEFLLNKGLIQEDEIVVFSAGVPVGSGGTNMIKVERV 487
463 0.000e+00UniRef50_A0A2H0AJC8 Pyruvate kinase n=2 Tax=Deltaproteobacteria TaxID=28221 RepID=A0A2H0AJC8_9DELT  ali  37  8..................RRTKIVATVGPACAEEETFAALLAAGVNACRLNFSHGAHAEKKQWIERIR-AHAARQGKNIAILGDLQGPKIRTGHMAPGG-VILECGGRAVVTTRDVV---GNQELISTCYAPFPQEVRPGDRILMNDGFIELEAVRTLSSEDVECRVITGGALGDFKGINLPGVRISTPALTEKDRQDLEFCMAEGLDYVALSFVRNAEDVADLKKILYENGADLRVIAKIERPEAVEGFDAILEAADGIMVARGDLGVEMRPERVPLIQKRIIRQCNLAGKPVITATQMLESMIKNPRPTRAETSDIANAVLDGSDAVMLSGETAVGAHPVAAVTVVAQVALDVEQD-STLRAHRHVPSASSGYREQPEAIGRAACRTAEEVEAAAILAFTQTGSIAAILAKYRPSVPIIAVTPSRNVQRRMALYSGVSSLLV------ASEGTTEEQICTVEKTVLAHGDLKKGDVVVITMGSPISAGTTNLMKVHR. 477
464 0.000e+00UniRef50_Q46078 Pyruvate kinase n=2397 Tax=root TaxID=1 RepID=KPYK_CORGL  ali  35  3..................RRTKIVCTLGPAVASADGILRLVEDGMDVARLNFSHGDHPDHEQNYKWVREAAEK-TGRAVGILADLQGPKIRLGRFTDGATV-WENGETIRITVDDV---EGTHDRVSTTYKNLAKDAKPGDRLLVDDGKVGLVCVSV-EGNDVICEVVEGGPVSNNKGVSLPGMDISVPALSEKDIRDLRFALKLGVDFIALSFVRSPADAELVHKIMDEEGRRVPVIAKLEKPEAVTSLEPIVLAFDAVMVARGDLGVEVPLEEVPLVQKRAIQIARENAKPVIVATQMLDSMIENSRPTRAEASDVANAVLDGADAVMLSGETSVGKDPHNVVRTMSRIVRFAETD-------GRVPDLTHIPRTKRGVISYSARDIAERLNARALVAFTTSGDTAKRVARLHSHLPLLVFTPNEAVRSELALTWGATTFLCPPVS------DTDDMMREVDRALLAMPEYNKGDMMVVVAGSPPGVGNTNMIHVH.. 464
465 0.000e+00UniRef50_A6LLI2 Pyruvate kinase n=10 Tax=Thermotogae TaxID=200918 RepID=A6LLI2_THEM4  ali  37  1.................MRKTRIVSTIGPATESEEMLEKLIKAGVNVFRLNSSHDDLETHRIRIKRLKKLREKL-NAVFAILIDLSGPKIRTGKLKKE-YITLKEDSIIEITTEDVL---GDEKVLSVNYMRFPFEVKKGDKVLINDGAIELEVLGT-KDNIVEAKVVRGGKITHHRGVNLPGVDLSISAITEKDKEFIRLAIEENIDFIALSFVRKPEDV----KLAKSLSNGIPIIAKIETAQALEYLQEIILESDGVMVARGDLGVEIPLSKVPIVQKQIIEIANRFAKPVITATQMLESMIKKPTPTRAEVSDIANAILDGTDAIMLSAETSIGNYPIEAVNVMNEVAQNTEKFIDYESIELEWIRSYYISEDIEAAISHAVYNLSKDVDARLIITATGTGRTAINVARLRPSVPIMAATPNVSTLYKLSLVWGVMPVLI------NQTLSTDEMINEVMKKAKELDLAKKGNRVIITAGIPWGPGTTNTLQIQEI 469
466 0.000e+00UniRef50_A0A0P6XM97 Pyruvate kinase n=8 Tax=Bacteria TaxID=2 RepID=A0A0P6XM97_9CHLR  ali  37  3..................RRAKIVGTIGPASENETTLRCLIEAGLDVARLNFSHGTHEEHAARIATIRKISQEL-DKPVTILQDLQGPKMRVGNLPKEG-IPLTVGEKILLAPSEQLRDSGERTLVPMEVPNLARAVKKGNRILLDDGHLELEVLDVKDG-IIEAQVVLGGILYPHKGVNLPGVSLGIPCFTEKDRADLEFGLQAGVDVVAISFVHTAEDVETVRNAIRELKSDTPIIAKLERPQAIENLHEIIHMADGVMVARGDLGVETSPSTVPIIQKRIIDMANRHAKYVITATQMLDSMISNPRPTRAEASDVANAIFDGTDAVMLSGETASGKYPVESVKMMDSIIREAEANAKTWGHYATSPVDASEEN--AFAITRAARELAHDRKAAGIAVFTQTGKTALLMSKSRPEVPILAFTPEERTYRRLGMYWGVTPFLVP------FASTVEGMILSLEAAILSATTIKPGQQVVVITGFPVG............ 468
467 0.000e+00UniRef50_A0A1F7F1T9 Pyruvate kinase n=1 Tax=Candidatus Raymondbacteria bacterium RIFOXYD12_FULL_49_13 TaxID=1817890 RepID=A0A1F7F1T9_9BACT  ali  37  1.................MRKTKIIATIGPASSSPEMLKKLICAGVNTVRLNFSHGVHADHLKVIRCVRALSISLK-QPVGILQDLQGPKIRLGTFKKG-PVLLKKGARFTITTRACV---GDEHIAGTTYTKLHKDVRPGNIVLINDGLVRLTVLAVR-GRDVIMRVVVGGVVSNHKGINLPGVRVSEPSVTSKDRIDLAFGIRHNVDYVALSFVRTANDIRKVKAIVARSGKNIQVIAKIEKPEAVEQCHDIIDAADGIMVARGDLGVELSPEAVPAIQKKLIACAAKQNKIVITATQMLESMTEHPTPTRAEASDVANAVYDGTDAVMLSGETASGKYPMETVRMMHKIALAAEESHEKSGYFTDALDTPAIQAAANAAL-----YICEEILGKAIIVFTMSGSTARLIAKNKRRETIIALTPDRDVLNQLSLVWGVVPLYLPYMRNS------DDMIKKGLAAAQKSGLVKHGDKVVIVSGNAYHAGSTNMIKVAT. 467
468 0.000e+00UniRef50_A0A1I2HZR0 Pyruvate kinase n=1 Tax=Thermoflexibacter ruber TaxID=1003 RepID=A0A1I2HZR0_9BACT  ali  35  6.................HNRTKIVATVGPASNSKEKLLELMIAGVDVFRLNFSHGTHEEHQKVINHIRELNAKFGG-NVAILQDLQGPKIRLREIEGG-SITVAKDETVVIAYEKEV---GTREKLTSTY-DLAQDVKPGEPILIDDGNIELRVTAV-EGNRVITKVVYGGVIKPKKGINLPNTNVSEPSLTKKDREDLAFGLQNEVDWIALSFVRQATDILELKQIIKDSGKNSKVIAKIETPTALKNIDSIIEATDGVMVARGDLGVEIPLEEVPIEQKRWVRRCNVAAKPVIVATQMMESMINNPRPTRAEAGDVANAVIDGADAVMLSAETASGHYPVETIQNMVRIIHSAERHPDIYNRNYHLDKNSPNFY--AQSLVSHACKLAKEVGAKAIIGITQSGSSAFRLSSYRSESQTFIFTNNMSLVTTLNLLWGVKCFYYDNFVSTN------QTFEEVEKILVNAGHLQKGDIYINMASIPMKKKKTNMLKLSWV 474
469 0.000e+00UniRef50_A0A2H0N4T0 Pyruvate kinase n=3 Tax=Candidatus Magasanikbacteria TaxID=1752731 RepID=A0A2H0N4T0_9BACT  ali  38  3..................KRTKIVCTIGPASEKQDVLKKMVDAGMNVARLNFSHGTYENHALLIKNIRAVEAQ-TGEPIAIMQDLQGPKIRVGVLPGEG-IELKENQKVVFST---AMTEYQGESIPVDYTELHEHVQSGERMLLNDGRIEVKIEKVVE-KEIHTHVVVPGKLTSHKGINVPDSHLNIRAMTEKDKQDARFGVEHGVDYIALSFVMGPSDILDLRYLIKDYEKPIRIIAKIERNDAVKNIKEIMEVVDGIMIARGDLGIEIPAAEVPLVQKRLVDTALEYGKPVIVATQMLDSMQENPRPTRAEVSDVANAVIDHTDAVMLSNESATGKYPVETVHTMAEIIVEAEKSVYDNIPLREYKEKETQIDNIISGLSR---LLAEKVNAKLILAASISGETGRLISRYRPELPIAVATAEERVRHQLNLSWGVVPFILPTC------KSIEELVERSLVYLKKNKHVKIGDNIIVVAGEPVGAGHVNLLEVREV 478
470 0.000e+00UniRef50_A0A1V5ZG06 Pyruvate kinase n=1 Tax=Candidatus Latescibacteria bacterium ADurb.Bin168 TaxID=1852850 RepID=A0A1V5ZG06_9BACT  ali  37  2.................IRRTKIVCTIGPQTASIEQLRALVDAGMNVARVNFSHGTHERHRSVIRAVRTLRGQY-GEPIGVLADLSGPKIRLGKLPGG-SCEVETGQTIILT-RDTGGECGD--RFPINYPYLSEDVKVGDSVVMNDGDVSARVTDIRGG-DVVCLVEDGGMLGDNKGVNFPDSALRVDAITEKDRRDVRFALEEKVDFLALSFVRRPEDIVSLRRLVAGGPHTPRIVAKIEKREALENFGAILAEADGIMVARGDLGLETELARVPMVQKDLIARARAAGKPVITATQMLESMIVNPVPTRAEVADVANAILDGTDAVMLSGETAVGRFPVDTVRMMARIAAA--TEAAHQPANGFRRNADRGVLTPSEAIGQSTAQMAWDLHVVAIVVCTDSGKTGRVVSRFRPAIPIVAATPNEEVARQLTLSWGVVPALLEPITS------TDELIAHAFATVKGTGIAKNGDQVVITAGIPFGGGGTNLLLVQQI 471
471 0.000e+00UniRef50_A0A1H0QMU3 Pyruvate kinase n=2 Tax=Clostridiales TaxID=186802 RepID=A0A1H0QMU3_9CLOT  ali  42  1.................MRKTKMICTVGPASETDAILSQIIEAGMNVSRHNFSHGDHAEHKTRIEMVQRLAKE-KNNHIGVMLDTKGPEIRTGKF-DPKKVELQVGTEFTVYAGGDVI--GDTTKCSVTYEGLANDVKPGNTILIDDGLVGLTVVSI-SGNAIKCTVQNTGFVATHKGVNVPGVSIKLPALTEKDKSDLIFGCEMGVNLVAASFIRKAADVKAIRAILVENGGDIQIFSKIENQEGVDNIDSIIEASDGIMVARGDLGVEIPMENLPAVQKMIISKCNEAGKAVITATQMLDSMMRNPRPTRAEVSDVANAIMDGTDAIMLSGESANGDWPVESVQTMAKIALEAEKQLSYEVAVSKSKKHIPA---IAGVISRGACNAANELKASAIISSTQSGATAMRISQCRPDCPIIAVTPNERVAKSLALYSGVYPIVAQEM------KSTDEIIERSVKVAQENGFVTAGET...................... 448
472 0.000e+00UniRef50_A0A1V6A9F5 Pyruvate kinase n=5 Tax=root TaxID=1 RepID=A0A1V6A9F5_9BACT  ali  34  2.............EKIILKRTKIVATLGPASSDPAVIEKMINAGANVFRLNFSHGNHETHLKNIKQIREISEK-TGIYVGILGDLCGPKIRVGKFESGFAV-LEMGDHFFLSEDPLCV--GTKAGIGTSYPYLTKDIKPGNIVLLDDGNIMLEAL-YPEDNRFYFRVLAGGVLKDKKGLNMPGINLSVETITQKDKEDLRFIIENELDFVALSFVRRAQDVIELKQLL--NGADLRIIAKIEKPEAISELDKILDNCEGVMIARGDLGVELPVQTVPAIQKQILKRCSDRGKTVITATQMLESMMENQIPTRAETTDVYNAIVDGSDAVMLSGETAAGKHPVKAVKMMADIALEAEKAVGAVNFHYILPGVERK---LEEVMAQCACEASYNACSKAIVTFTHSGNTALNISKYHPPTLIFALTPFQKTCRRLSLSWGVVPVIVKDM------KSTDEMLAEAEQVMKRLEVVKSGEIITMVAGLPIGVGNTNFMKLHKV 473
473 0.000e+00UniRef50_A0A2G6N2A0 Pyruvate kinase n=2 Tax=Proteobacteria TaxID=1224 RepID=A0A2G6N2A0_9DELT  ali  35  4..................RRTKIVCTLGPTSDDEATLEKMMRAGMDVARLNFSHGDHETHRALFARVRAVAERL-DRPVAILQDLQGPKIRVGDLLGG-SLTLAKGSEVTLVYAASTDEPAT---IPCTYEPLARDVNEGDRILLDDGRLQLRVLETCDGR-VEARVEHGGELTNNKGINLPGVTLSTPALTEKDKQDIELGRTLGVDYVALSFVRTPDDVEQTRALIS---PEAQLIAKIEKPEAVEHFEAILELSDGVMVARGDLGVEMGPQAVPLLQKAFIEAANARCKLVITATEMLESMRTSPRPTRAEVSDVANAVLDGTDALMLSGETAHGEHPVESVQMMDHIARSTEASARFSSL---TGPTSLNLRETSNAIAKAAVVATRELGAAAIVCYTESGATALMISEYRPEVPLLAASHDPHVYRMLAAHWGVTPLLLKEVPNTA-----EEAVRSIRQAAVDRGYVRAGQSVVIASGTQID-GPNDMVIIETI 467
474 0.000e+00UniRef50_A0A2E3C5A7 Pyruvate kinase n=7 Tax=Proteobacteria TaxID=1224 RepID=A0A2E3C5A7_9PROT  ali  35  9............RQPQLPRHTKILATVGPASSKPEVLEKLVELGVNGFRLNFSHGSHDVHREVGKNIRALEEKHH-RPITILQDLQGPKIRLGQFADGAKHVLEVGATFTLDNDK---TPGTAQRVQLPHPEILEVLNEGDPVYVNDGVVKMRVTAKKDG-AVECVVEASGPVSDRKGVNLPGVDLPFSAMTDKDREDAKFGQELGVDWVALSFVQRAEDVQELRDLI---GPRSRIMAKMEMPNAIKRIDSIIDLCDGMMVARGDLGVEMPLEEVPPIQKRIIRRCREEGKVVVVATQMLESMTQNNTPTRAEVSDVANAAYEGADCLMLSAETAAGDYPVEAVEVMSRVIKRVEISPAWKPLMDA--RHPESVQNIGDAITLGAHRMSQQLDISAIVTFTSSGSTAMRMSRQRPLHPIMVLTPEKLIARQLNLGWGLQPHVARDVR------DFEDLVPLASQAMIERGLGAKGCNILITAGVPFGSGSTNMVRVVT. 480
475 0.000e+00UniRef50_A0A2M7EFM1 Pyruvate kinase n=9 Tax=Bacteria TaxID=2 RepID=A0A2M7EFM1_9BACT  ali  35  1.................MRKSKIVCTIGPASSSRETIHSLIKNGMDVARLNFSHGDHAAYKKITKLIREESGNLK-KTVAILQDLQGIKIRVG-FVSSGSVVLKNGAEVFLHSGSDI---STDKHIFISYPALKRDVKVRGKVLFDDGLIQANVTGKTRDG-LRVKIVEGGVLRSKKGVNLPHVKTTLPSFTDKDKNDLNFGLKIGVDYAALSFVRSAGDVRDAKEWLKKRHASLPLIAKIEKPEALDDIDGILDEADGIMIARGDLGVEISPEEVPIIQKMLISKANDKGKLVITATQMLESMTEHSRPTRAEATDVANAVIDGSDALMLSAETAAGKYPLDAARMMDRIIRYTESRSLLRRDYSSFANLFSDFSGAVAEAAC---TAAGDIHAKAIVAFTQSGFTARLVSKFRPEVPIIGITPYYNVKRRMSLYWGVTPMLI------SHVSNTDSMIQKVEKLLIASKIAKKGDNIVITAGSPMKRGTTNLMKLHKI 469
476 0.000e+00UniRef50_A0A2D6CT85 Pyruvate kinase n=1 Tax=Candidatus Poribacteria bacterium TaxID=2026781 RepID=A0A2D6CT85_9BACT  ali  37  4..................RRAKIVCTLGPASSDESTVRALAEAGMDVARMNFSHGSHAEHAERIALTRKVAADV-GLPLAALLDLSGPKVRTGTLANGPAL-LKAGERFILTAGEA---PGDAQRVSMNYPGLVSEADIGDGILMADGALELRVADVVGD-DIVCEVVVGGELGEHKGINVPTKALTLPSLTEKDERDLRFGLAQGVDWVALSFVRTREDVIAAKRMIADAGHATPLIAKIEKRAALDNLEDILDEADGVMVARGDLGVEIAMHEIPWAQKEIIRSANARGLPVVTATQMLESMIENPRPTRAELTDIANAILDGTDAVMLSGETAVGKHPVRAVRIMREVA----TAPGAVGPDVPANPSRGPMNSIKNAISRSACRLAEHVDADYIICCTRSGETARAVARFRPSVPILGVSSNEGVLRQLQLSRGVFPLGIPEPT------DTDDLIRKGEGAALDAGLPWRSGVVVIVASSPLDTTTTNMIKVQAV 470
477 0.000e+00UniRef50_W4XEK3 Pyruvate kinase n=5 Tax=Deuterostomia TaxID=33511 RepID=W4XEK3_STRPU  ali  44  31.TFLDHCSKLHIESRPNVRNSGIVCTIGPVSRSVDTLMDMIKNGMNIARMNFSHGSHEYHAETIKNVREAERRLTQVRIAVALDTKGPEIRTGLLAGGGSVKLETGKIIRLSLNTADAESGTAEKIYVDYPNMRKVLDVGGTVFVDDGLIALAVTAIGE-----------------------------------------F--EKEVEMVFASFIRKATDVHQVREVLGEQGAHIKIISKIENQEGVAKFDEILEASDGIMVARGDLGIEIPPEKVFLAQKMMISRCNKIGKSVICATQMLESMVNNPRPTRAETSDVANAVLDGADCVMLSGETAKGKYPVEAVSMMHRISREAEAAVFHRQQFEELTREVDMPTSAGLTVAIAAVEASYKCLAGAIIVLTKTGRSAHMISRFRPLAPILAVTRDQVIARQIHLHRGCFPLLYPEEKDRNWSEDIDNRVKFAVEIGKGRKFFEDNTPVIVVTGWRSGAGFTNTMRII.. 493
478 0.000e+00UniRef50_A0A2B8A1Y4 Pyruvate kinase n=3 Tax=Cytophagales TaxID=768507 RepID=A0A2B8A1Y4_9BACT  ali  36  7..................NKTKIVATIGPASNTKEMLRQLIIAGVDVFRLNFSHGVHEDHRKVISLVRELNAEL-GTMISLLQDLQGPKIRVNEM--EPNIVIAPGDEITITTHKVI---GNATLISTSYQHLPKDVKPGDPLMIDDGKIELKAI-KSSGDNVLCKVVYGGLLKSKKGINLPKTNVSAPSLTEKDMEDLRFGMQHRMDWIALSFVRTAEDIFSMREILKANNSSARIMAKIERPEAIKNIDSIIDAADGVMVARGDLGVEIQMEEVPLAQKMIIEKCNQMAKPVIVATQMMESMIENPRPTRAETNDVANAVLDGADALMLSGETAAGKYPVEVINCMVHTIEAVEDTGKIFYRYRDVDLNSARA--ITDSVILTACKLAKEIKAKAIVGMTQAGYNIYRASSHRPDAKLFAFTHAEDAINSINLVWGAKAVYYD------QTTSTDETISDVEKILVDSGELKTGDIFIFLASMPIQRGLTNMLKVHRV 474
479 0.000e+00UniRef50_A0A1Q7QUE9 Pyruvate kinase n=9 Tax=Archaea TaxID=2157 RepID=A0A1Q7QUE9_9ARCH  ali  37  3....................TKIVCTIGPASSSPRALGHMIRAGMDVARINFSHGTYEEHLKNIKSIRKVSHNLR-RPVAILQDLPGPKLRVGRLVQE-PMHLRRLDTVTLTTKPSKAKG----KIPVAYPDLPKTVRKGDTIYLADGSIRLEVLRTTRDK-VEARVLVGGDLISGKGLNLPRLRARVPAITREDREHLHFGFENNVDMVAVSFVQRADDIRSARKVASEKGREIFVVAKIEKKEAVENLEEIVKEADAVMVARGDLGVELSLERIPIVQKRIIFEANRQAKPVITATQMLESMISAPTPTRAEVTDVANAILDGSDALMLSEETAIGSYPAEAVKTLQKVAQETER---YLPKQITQQRREWHENSQEDAIAFAACETALQISAAAIVTPTRTGKTARRVSKYRPPLPIVALTSQSEVEKQLLLSWGVQTVRRE-------MESTESIFTEAEKTVKRLRLARKGNTIVIVSGDPKGPGRTDLLKIQRI 466
480 0.000e+00UniRef50_M2XB74 Pyruvate kinase n=1 Tax=Galdieria sulphuraria TaxID=130081 RepID=M2XB74_GALSU  ali  50  50..................RRTGIICTIGPKS--LPRIGELLDAGMNVMRLNFSHGTHEYHESCIRKLREELKKRPGMLCAIALDTKGPEIRTGLFVNSTDVRIEKGSQVTITTDEQFREKGTASKFFIDYKSLCTTVKPGMYIFISDGVLRLKVKECRE-TEVICEAINSAVIGDQKGVNLPGAKVDLPAVSKKDIDDLRFGVQQGVDVVFASFIREASQVLEIRKLLSEAGKDIKIFSKIENQQGLDNFDEILKVTDGVMVARGDLGIEIAPAKVFVAQKKLIRLCNIHAKPVICATQMLESMVNNPRPSRAEVSDVGNAVVDGADCVMLSDETAKGDYPIESVQHMDLICVEAEGFLGYEKIWAEMRASTPRPMENIESVSCAAVMLSFDEEVKLIVLVSENGKLARNVSKYHPNVPVIAITRNPRVARQQLLSRGILSLLVDSSEFS----SVNNLLNIACHAAVEVNFCKPGDK...................... 505
481 0.000e+00UniRef50_A0A1V5T827 Pyruvate kinase n=1 Tax=Spirochaetes bacterium ADurb.Bin269 TaxID=1852911 RepID=A0A1V5T827_9SPIR  ali  39  4..................RKTKIVCSMGPTTENLDVVCELLRAGMNVARFNFSHSNHEYHKRNMENVRKAS-RITGIPCALLLDTKGPEIRTGLVPGDGKIEIREGDIFLVTNDDSPSIAGSPGRISLSWKKLPSEIKKDCRILIADGLVELLVLDTDGTSTITCRALNSGSIGSRKNVNVIGIHPDVPVLSEQDKKDIEFGLSMGIDFIAASFISSPADVVSILRFIEPFNTKVRIISKIENEEGLDNIEDIIAVSSGIMVARGDLGVQLATERIPLAQKKIIQACNLAGKPVITATQMLDSMISNPRPTRAELTDVANAIFDGTDAVMLSGETANGAYPVEAVKTMAKIARTVESSEEYKRKMRDDHRFDRKHSGIAEIMTHAAYQTATDIEAAALVSPTLSGNTARLLSMFRPEQPIIAATPNETVQRQLLLNWGVVPLLV------TIADDSEEMIQNTMRVAIDTGYLKKSDKVVMVAGVPIISPMMNTIRVFFV 504
482 0.000e+00UniRef50_A0A1V6H357 Pyruvate kinase n=1 Tax=Thermotogae bacterium ADurb.Bin062 TaxID=1852923 RepID=A0A1V6H357_9BACT  ali  35  1.................MRKTKIVSTLGPASNTETMIERLIDAGVNVFRLNTSHGKIEEHTETVRLIKRIRERRH-APIGILIDLEGPKIRIGPFQSG-SVLLTKGQSFILTAQDIL---GDENRVSVSHKRLPKEVRSGDSIMIADGLIELKVRS-ADGTEIVTIVENGGPLSGRKGVNAPGVDLGLEAITEKDKTYIRMAVEEGADYLAQSFVRKPEDIDVCRSEIRRLDSSIPIIAKIETKQALGYLNSILYKSDGVMVARGDLGVEIPAQEVPLIQKKLIAMANAQSKTVITATQMLESMIENPRPTRAEASDIANAILDGTDAIMLSAETTVGRYPVEAVRMMADIANVIEKNWFQTRPFENPLIQEIFLDNPEEAIAHATCDIARQLAIEVIVTSTVSGKTARMISKYKPPSTLLGITPELATYYRLALVWGVWPVLVERTRS------TDEMMAIAERKAMDCGLVKKGERLLLTAGIPWGSGSTNMLKIHT. 473
483 0.000e+00UniRef50_D4S1K4 Pyruvate kinase n=12 Tax=Bacteria TaxID=2 RepID=D4S1K4_9FIRM  ali  39  1.................MRKTKIICTLGPAVDSDERITQIINAGMDCARLNFSHGTHEEQEVRLNRVRRIAGEL-NRHIPILLDTKGPEIRLKDFENG-SVVVEKGSLFTFDTDKE--TPGTKERIGLTYDKLAKNVEVGTKILVDDGKIELKVTAI-KGSKVICKVITGGKLSNHKSINIPNVEIPMPYLNDVDKSDLLFGIEHNVEYIAASFVRCADDLKKLRKFLKDNGGDIKVISKIENGQGINNFDEILELSDGIMVARGDMGVEINFEKIPAIQKMMIEKCNREGKIVVTATQMLESMTENPRPTRAEVSDVANAIYDGTTVIMLSGESAAGRHPVEAVRTMANIAVNAENTINYYEKYVDSSADMEP--NLKNAICASAYNAAKYLDAKAIVVLTRSGATANILSRFHPECPVIAATISERGRNQLNLVWGITPVAAEN------LDSADKFVEYAVSKAVESRLVKRGDNIVVILASDLESDD-DTMRICTI 470
484 0.000e+00UniRef50_A0A0V0QFX1 Pyruvate kinase n=1 Tax=Pseudocohnilembus persalinus TaxID=266149 RepID=A0A0V0QFX1_PSEPJ  ali  40  41............ETTNTQKRTKIICTIGPACWEVDTLVKMIDAGMNIARLNFSHGDHEGHGKVVEKIREAMKQRPQIPVGILLDTKGPEIRTGFFKDGKSIELKKGQDLEITTD--YDFLGDENGFACSYKNLCNSVKVGGQILIADGTLVCIVKEI-KDKSVIVTVQNNAKIGERKNMNLPGCKIDLPTITEKDENDLEFGLKYNVDFIALSFARYGDDIDECRDILGPRGSHIKIIAKIENQEGLHNYEEILEKTDGIMIARGDLGMEIPTEKVFLAQKWMAKLASDKGKPLVVATQMMESMINNPRPTRAEASDVANAVLDGSDCVMLSGETANGAFPVGCVETMSKICIEAENCFENETRFWTLMRSQQQKLSGLESLASSAVQISFEMDLPAIVVFTQGGTAARLISKYRPRAHIIAVSDQSSTVKGLCATSGAICLRVPTIQAGQ-----EKLVDYAIEQGVKFGLCEQGQSIVVL.................. 505
485 0.000e+00UniRef50_A9F8Y8 Pyruvate kinase n=17 Tax=Myxococcales TaxID=29 RepID=A9F8Y8_SORC5  ali  34  3.................VRRAKIVCTIGPSCDSQTTLEQLIRAGMDVARLNFSHGSHEDHGKAIATVR-AAAEACGKPVAILQDLCGPKIRAGRFP-GNTFEVADGASVTLIEANRDSPVATPGEIPILYEGLASDLQPGDVVLIDDGRVVVTVTKV-EGERVHAGVTQGGRLRDRVGVHLPARRVRISALTEKDKADLSFGLAQGVDYVALSFVRNADEVRHVRDICEAWGRPTPIVSKIETPGAIDNLESIILASDGVMVARGDLGVEFNPERVPIIQREILGLARVHQKPVIVATEMLQSMVTATRPTRAEASDVATAVFDGTDAVMLSQETATGAHPPLVVRMMARIVTEAEQSSFYRYLSSE---QPGQRANVPEATARAACDIAKDIGAKLIIAFTESGLTARYASKARPVVPIVAFSPNDTTRRRLALLWGVVPFPVDALRNS------DEMIERATGYLLANGLVSPGDKLVTIFGAPVGSGSTNTIRVKVV 474
486 0.000e+00UniRef50_A0A090CYZ7 Pyruvate kinase n=28 Tax=root TaxID=1 RepID=A0A090CYZ7_9BACT  ali  38  9................KMRRTKIICTIGPAVSSYEKIVELIESGMNVARLNFSHGTYADHLDIIEKLKRARKE-TQVSLAIMLDTKGPKIRLGSIEGG-IVKLEKDQIWSLTQD---IVKGDQNEATIVPGFIINEIPVGSRVLFDDGYIAGEVVDKT-NKDLKVKILNAGSLKSGKSVNLPFTRLSLSSPTEKDIQDIHFGCDHDVEFIAASFVRSAEDIVAIKKILAERGKPIQVIAKIENHEGITNFDSIVQIADGIMIARGDLGVEVPLMQVPKLQKMMIRKCSHAGKPSVTATQMLESMIKNPRPTRAEASDIANAIYDSTSAVMLSGETATGEYPIECVKMMKSIVEESEGDFDYKGFFN--QYAAKAYNDVPSAVTLATVKTAYSCSATAIFAFTNAGSTARLLSRLRPEIPILGLTPLEKCFHQLSLYWGVIPVLYDKGR------NFFESFSYLSDFALKHEIVKNGDLVLATVGTPFGSGTTNTMMVDSI 480
487 0.000e+00UniRef50_F2IJ39 Pyruvate kinase n=2 Tax=Bacteroidetes TaxID=976 RepID=F2IJ39_FLUTR  ali  35  1.................MKKTKIVATLGPATAKKEVLKQMILDGLNVCRLNCSHGSHEDHKKSIDMIREINKE-TGLNVSILADLQGPKIRTYEMENNG-VMMEEGSIVTIVTERI---TGTAERFGISYSLMPRDVLPGERILLDDGKLQMEIVSTNGESEIKAKVIHGGILSSKKGVNLPNTKISLPSLTEKDREDLEFALNNDVDWIGLSFVRSARDIIELKHIISNRQAKALVVAKIEKPEAIDDIDEIIKVTDALMVARGDLGVEIPYQNVPLIQKMLIRKGHQHAKPVIVATQMMESMITNITPTRAEVNDVANAVLDGADAVMLSGETSVGKFPNEVIRTMVNIVDEMEK--FDGIYHKDQLPDKSQSRFISDSICFNACRLAQRVEADAIITMSYSGYTSYKIASQRPNAPIFVFTGNKQIITQLSLVWGVRAFYYDKKVS------TDHTIADIKYLLAKEGLLKQGDLVINIASIPIEEGKSNMLKLSYV 471
488 0.000e+00UniRef50_A0A2E4HW14 Pyruvate kinase n=5 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2E4HW14_9BACT  ali  35  2...........TRPRDPYRRTKIVCTLGPASETLEQIRALFAAGMDVARLNFSHQTIDWHRERVAMIRGISAE-AGRPIGILQDLPGPKIRVGNFPDG-PVELKVGQEFTLTAG---GTDGDNGGVSINQKALIEAVEPGDPILLSDGTIRLRAAHIEKD-SVVCEVTVGGRLGSHKGVNLPNRTVALPSMTDYDHEALIAGLDMGVDFVALSFVRSPDDVEIARKVIEEHGRHVPIIAKIEKFEALENLEGIIEAADAVMVARGDLAVEIPLWDVPQVQKQVIKAANMAAKPVITATQMLLSMVDSPQPARAETSDVANALYDGTDAVMLSEETAVGSYPVEAVEVMANICVATEKKLCRPGSY--LKLPADRHHLVPDVVATAACMVARHLNAMALVVPTRTGSTAIKIGACRPSQPIIAIGTHIETVARMTLVWGVVPIYGEDLXTH------ESMLMEAERRAEASGLIKKGDLLVITAGFPVGPGSTNTVTV... 474
489 0.000e+00UniRef50_F7V0P3 Pyruvate kinase n=73 Tax=Bacteria TaxID=2 RepID=F7V0P3_EEGSY  ali  35  3..................KRTKIICTLGPAVDDKRLLKQLIAAGMDIARLNFSHGTHAEHAERIARLRRVCAQV-GSPCAVLLDTKGPEIRTGALVGGKAVSLNAGDELVLTEE---SIEGDAHRITQTCVGLAAYVRPGTTLLLDDGLIELEVIS-LEGTDLRCVVKNPATLGERKSVNVPGVTVPLPVMTDQDRADLIFGIEQGIDFVAASFIRSAEAIREIKAFLADHGGRIGVIAKIETVEAVDDIEAIVEVSDGVMVARGDLGVEMPAYRVPHIQKKIICRCNERNTPVITATQMLDSMIRSPRPTRAEVADVANAVYDGTDCLMLSGETAVGAYPVEAVYIMGRIAEESEPYLTEAAGLREASR-EEGHGSVSVAVGMAAVRAAETLGARCIVAPTMSGRSARLMASFRPRQPIYAVTPMPEVMRAMQLYWGVTPLL------GDVQGDTDFVIEQARRIVRERGLVEVGDIGVFTVGDRDTSPNTNIMYVVQ. 480
490 0.000e+00UniRef50_UPI00083F0FD6 axoneme-associated protein mst101(2) n=1 Tax=Drosophila busckii TaxID=30019 RepID=UPI00083F0FD6  ali  45  63.SQLDYKARLQIHAPREFPLSGIVCTIGPASNNPETLLKLISAGMRVVRLNFSHGSHDFHCQTILAARKAVECYAKKSVAIALDTKGPEIRTGQISGGAEIQLSRGDQLRLTTKREYETKCSKEILYVDYDKLPKLVAPESRVYIDDGLISLLVKDI-KDSEILCEVQNPGKLGSRKGVNLPGVKIDLPAITEKDKLDLKFGAEQNVDMVFASFVRDADAIHEIRDVLGPNGKHVMVISKIENQQGLDNLDEIIEASDGVMVARGDLGIEIPAEDVVLAQKSIIAKCNMLGKPVICATHMLQSMTNRPRPTRAEASDVANAVFDGADCVMLSAETAKGNFPVESVQCMSNICSKIESVLWYDRIQSDVKSIVKSSTDQLSAVTSGITEAASLSDAKAIVIASPCSLVPQMVSQFRPRCPVIMLTGDPRQARQSVIYRGVYPLIVEEMAWGCT--DFRRILQSGVEQMAQMKFVKFGDRIVIV.................. 551
491 0.000e+00UniRef50_H3FAW0 Pyruvate kinase n=3 Tax=Opisthokonta TaxID=33154 RepID=H3FAW0_PRIPA  ali  51  974.THLEHLCKLDIREPPHVRKTGIICTIGPACRSVEMLQKMILNGMNIARLNFSHGSHEYHAETIVNVRTAIESFSERLIAIALDTKGPEIRTGLLTGGGSVELKRGSSITLSTDPKLKNSGTAVNLYVDYKNITKVVSSGSKVFIDDGLISLIVDEVHED-AIVCTVENGGMLGSRKGVNLPGTAVDLPAVSEKDIKDLKFGVEQGVDIIFASFIRNAAGIRAIREILGEKGQHIKIIAKIENQEGVDKADEIIAEADGVMVARGDLGIEIPAEKVFLAQKMLIAKCNRAGKSVICATQMLESMVHKPRPTRAEGSDVANAVLDGADCVMLSGETAKGEYPLEALQIMHYICKEAESAIYHSKLLDELLMNTPRPTDMTHTIAISATTAAVLCKERTVDWPT----------------------------------------------------DVDGRIQFGIDVGKERGFIHTGDNLVVITGWRQG---TNLL..... 1415
492 0.000e+00UniRef50_A0A0C1S9J8 Pyruvate kinase n=6 Tax=Enterobacterales TaxID=91347 RepID=A0A0C1S9J8_9ENTR  ali  41  1.................MKKTKIICTIGPKTESEFMLSQLIDHGMDAIRLNFSHGSHQEHGRRIENIREICNK-KKRQIAILLDTKGPEIRTMKLKKNKNVVLVAGQHFVLTTNSSIL--GDHNHVAVTYKNLHNDLKKGDSILIDDGLIEMRVLYI-EDEKIICKVLNNGILGENKSINLPGVTVNLPALSEQDRKDLIFGCQKGVDFIAVSFVRRRSDVEEIRNVLKNHGKKISIIAKIENQEGLNNFDDILEISDGIMVARGDLGVEIPAEEVIFAQKMMIAKCVESSKIVITATQMLDSMIKNPRPTRAEAGDVANAILDGTDAVMLSGESANGKYPIESVKIMSTICKRADIVMNH----INYNKVYRRKITITEAVCHSAVEISENLDSKLIIVATFGGKSAKSIRKYFPKAPILALTTQKETVNQLLLVKGVFPKLVERFIS------TDDFYIIGKKIAIEEKVGKKGDIIIMVCGALVPSGTINTSSIH.. 468
493 0.000e+00UniRef50_A0A2N6DCG8 Pyruvate kinase n=8 Tax=Bacteria TaxID=2 RepID=A0A2N6DCG8_9BACT  ali  38  1.................MRKTKIVATLGPSSFDRETISDMIDAGMNIVRLNFSHGTHEQHGQTIDLVRELAED-KGVCISILQDLCGPKIRLGILPEEG-IRLLPGDTCVLAAEQYA----TGDVIPVQYDGLEKDLSIGDRILLADGAMDMMVED-FNGHNVTCRVLNGGIAFSKKGVNMPTTNLSIIAFTEKDKKDLIFGLEKGVDIVALSFVRDAADLVKIRDMISRDVNQPLLIAKIEKPQAVKNLDEILEMVDGVMVARGDLGVEMSLYEVPVIQKQIIQKARREGKSIITATQMLKSMVSNYRPTRAECTDVANAIFDGTCGIMLYEETASGEYPVEAVSVMNRIALATEQNVEFRLDLSNEEHISDK--SVAWAVGRSASWLSKDLDAKAIVAYTNSGFTARAVARFRPEAPILGVTPNIHTYRKMNLSWGVAPVLCGNF------DDAEEMFSSAAEMAVSQGYARKGDKIIITSGIPLGAGSTNLIRVYEI 469
494 0.000e+00UniRef50_A0A2M8PC90 Pyruvate kinase n=2 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A2M8PC90_9CHLR  ali  35  3..........KLVRKTDKKRTKIVATIGPSSSQESVLREMIRAGMDVARINFSHGDHEMHARNIALIRRIAAE-ENAVVAIMGDLQGPKIRLGKVI-GEPVPLRVGDRLTLTTRAELSEAAKQHVYPLPHAEFVRDVRAGQRLLVDDGTIEFKVL-TATSTDLHCEVIVEGALQSRKGVSAPESRLTLSALTEKDREDVKFALEHKLDYIAMSFVRSSKDIDELRWLCRYLNADVAIIAKIEKSEALQAFDEILRVSDGIMVARGDLGVETPAEEVPIRQKEIIRRCNEVGKPVITATQMLQSMIDNPRPTRAEASDVANAIFDGSDAVMLSGETASGKFPVLAVETMANIAVIAEQNFDRVARTDRVERANMTGEGFAVATSRTASVLADLLNARAIVTTTWTGSTARQVARTRPKTPILCVTPNETTLQRMALVWGVIPIYVPEFST------IDEMVQTVVRACYDQELVEFGDVLVLIAGMPFGAGSANFIKIHRV 502
495 0.000e+00UniRef50_A0A2H5XJI8 Pyruvate kinase n=27 Tax=Bacteria TaxID=2 RepID=A0A2H5XJI8_9BACT  ali  37  3..................RCTKIVCTLGPSSSDRETIRKLIQAGMDVARLNFSHGTXXX-XXXXXXXXXXXXXXXXXXVAILQDLQGPKIRIGDVEGGG-VLVHEGQRLVLTSRAERADG--RSRIYINYPTLAQDVEVGGRILLDDGLLELAVVAV-SDEDVITEVVVGGPLRSRKGVNLPHIRHSSPSLTEKDLRDLDFGLRMEVDLIALSFVRSEADVADLIRRVRDSGKQVGVIAKIEKPEAVAKIDQILAQADGIMVARGDLGIEMPLAQVPAVQKRIIRKCLAAAKPVITATQMLESMIDNPRPTRAEASDVANAVLDGSDALMLSAETASGKYPVRVVQVMDEIIRQAERHESEGRWLMTPRSATETAEAVTEAIGYTACQLAEQVGAVAIACLTATGNTARRIARHRPSVPVYAFTDNPRVATQLGLLWGTKAFAIP------FQRDTDQGVQLVHRLLREHGLVASGDLVVITAGMPPAKGRTNMVHVSRI 479
496 0.000e+00UniRef50_A0A2H5WWF2 Pyruvate kinase n=1 Tax=bacterium HR15 TaxID=2035410 RepID=A0A2H5WWF2_9BACT  ali  36  1.................MRRTKIIATLGPAVSSFEKICELVEAGMNVARINTAHGDWETRRQWISWVREAEKRY-GIPIAVLLDLAGPKVRIGNLP--APLMLQEGQTVRFVL--HAPDKPDQYDIPLPVPELFRVAQPNDRLLVDDGSIELRIRRVQEG-EMEAVVLEGGELRSQRGITLPNRILALPSLTPKDREDLKQGLDAGIDWVALSFVRSVSDVLNLQALIQEQNSDAPVIAKIEQRAALDDLEEIIEVSDGIMVARGDLGVQVDLAEVPALQKRIIRQCNARAKPVITATQMLESMIREGRPTRAEVTDVANAVLDGSDALMLSGETAVGAYPAQAVRWMARIAEHAEEELLLLNRLTHPVRITDAPHSTTEAVARAACLVAQMVDAKAILTPTTSGGTPRWVSHFRPAQPILALTDNERVWRRLALLWGVAPLKIP------HVSSTDEMTVQALLAARQTRLVHRGDRVVLTAGVPVNPGNTNMIQVLTI 478
497 0.000e+00UniRef50_K9QTG9 Pyruvate kinase n=46 Tax=Cyanobacteria TaxID=1117 RepID=K9QTG9_NOSS7  ali  39  7.................VRRTKIVATIGPATSSPEMLKAIIEAGATTLRLNFSHGSHADHQRNIRLIRQTAFEL-NQPVAILQDLQGPKIRLGKFENG-SIVLAKGDRFTLTNRPVV---GTQEISCVTYDYLAEEVPVGAKILLDDGRVEMVVEEINEKGDLHCRVTVAGKLSNNKGVNFPGVYLSIKAMTDKDREDLMFGLDQGVDWVALSFVRNPQDIIEIKELISSTGKQVPVVAKIEKHEAIEQMEAVLALCDGVMVARGDLGVELPAEDVPVLQKRLIATANRLGIPIITATQMLDSMVSNPRPTRAEVSDVANAILDGTDAVMLSNETAVGSYPVEAVATXXXXXX---XXXXXXXXXXXXXXXRDNRRSIPNAISQAVGQIAEQLGAAAIMTLTQTGATARNVSKFRPHTPILAVTPHVNVARQLQMVWGVKPLLVLELPS------TGQTFQAAINVAQEHKLLFEGDLVVMTAGTLQGSGSTDLIKVEVV 477
498 0.000e+00UniRef50_Q01WK7 Pyruvate kinase n=4 Tax=Bacteria TaxID=2 RepID=Q01WK7_SOLUE  ali  39  1.................MPNTKIVATLGPATDAPGVLRQLLAAGVDVFRLNASHGAQDAHAARIDAVRAAAREAH-VHAGILLDLQGPKIRLGRFENGG-VTLVTDAIFTITTEQVM---GTSERASTGYSRFAKDVKAGDRILLADGIIELIALE-SDGVSVQTRIVNGGPIGDHKGINLPGVQVSIPSLTEKDLADLHFGLNAGVDIVALSFVRTADDVRQLRDRLG--GRPVSIVAKIEKPEGYENIEPILDVTDGVMVARGDLGVEISLERVPRIQKSIIRRARRKGRFVITATQMLESMIENPRPTRAEVSDVANAIYDGTDAVMLSAETSVGKYPVEAVRYMAKIAAESEDSIRKKGYIDPPHQPQP---SNAEILADAAHHAARDSGAAAIVVFSSRGSSARLVSRYRPPVGVFAITPHDTTARQLSVSYGVTPLLAPDVSS------TDEMLSQMDRVLIEGGYLQKGQLVVFVAGQPVGPGTTNLMKLHRV 467
499 0.000e+00UniRef50_A0A1Y1RVN6 Pyruvate kinase n=3 Tax=Bacteria TaxID=2 RepID=A0A1Y1RVN6_9SPIO  ali  36  1...........MKQSVNLTKTKIIGTIGPASNSVPVLEKMIEAGLDIVRLNFSHGDHEFHAQAVENV-QAAVASTGRPVAILADLCGPKIRLGDLEADIPVT--AGDDLVITTEKFVGVPG---RVPTAYKRLAEDVNPGDTILIDDGLIRLEVRST-SGSDVHCKVKNSGVLKSRKGINLPGVKVSASSISEKDKNDLEFIISQPIDFVALSFVRSRDDIKELRWLLKDRGKLLPIIAKIEKPEAVADIDGIVAEADVIMVARGDLGVEMPTQDVPLLQKMIIEKCNMHNTPVITATQMLESMITNPRPTRAEASDVANAVFDGTDAVMLSAETSVGISPVDSVGIMDQIVSAAESRPELLKKSSFLKK--DHVLSDAENICRAACIMAEEAHASAIIAITKRGRTARMLSKYRISLPIIAFTETEETLRYMKILWGVQGEIMDNVGE------TDATLQKARKLALDLGHVKRGDKVVYVAGIPIESPSANMLKTETV 475
500 0.000e+00UniRef50_A0A2W4K832 Pyruvate kinase n=1 Tax=Candidatus Melainabacteria bacterium TaxID=2052166 RepID=A0A2W4K832_9BACT  ali  35  1.................MTRTKIIATIGPACRSKEMLEELIRSGMDVARINCSHASHEDIEGVIHDLRAIAKQL-DTSVGILLDLSGPKIRTGRIAGGKGVQLKVGQKFTLTSRKV---EGSSEIVTANYPRLSKEVKAGDTILLDDGIIELRV-KKSTETDAECEVLTAAHLKDHQGINIPGVRLSIPALTEKDRTDLVVGLKNEVDFVALSFVRDAKDIVDLREAIGDHWPPPMIIAKLEKPEAIDQLEAILDAADGVMVARGDLGVELPPEKVPPIQKMIIKRANQKAKPVITATQMLDSMANNPRPTRAEASDVANAIFDGTDAVMLSEETAMGSYPLEAVRMMDRIAYQAEATMSSRIVEHPLHTASQAVAHAAV-------AMALDMDARVVATFTKTGSTARLVSQFRPPVSIIALTQHEYVYRQLSLLWGTTPLMLTEVS------DSESTLALVEETLLKRGLVSPKDNIIITGGLPIAAGAANFVKLSTI 466
501 0.000e+00UniRef50_A0A2N4XIU3 Pyruvate kinase n=51 Tax=Bacteria TaxID=2 RepID=A0A2N4XIU3_9BACT  ali  38  2.................HRKTKIVATVGPASESEEMLLALAKAGVNVFRLNFSHGTHEDHQMRINRIRKINAEHGFK-CAILQDLQGPKIRIGQMETGEGVEIFAGDKLVFTNEDVI---GNGQRVSTPYKGMYQDVKLGERILMDDGKLEVKVTGV-DGMDVITEVVYGGLLKQKKGVNLPNTNISQPSVTEKDWEDLKFGLLNDVDWIALSFVRTADEIKDIQNYIKAQGKEAKVIAKIEKPEAVDNMDSIIAATDGIMVARGDLGVEIPSEDVPLIQKALVEKSNLAAKPVIVATQMLESMIDSPRPTRAEVGDVANAVLDGADAVMLSAESASGKYPILAVETMVKTIEKVEKKLYYRHHARVTEDSYKSEEKENDNVVMNACRLARDLKVKAIIGITTSGYTAVRLSHHRPKANTFIFTGNEKLLTQLSLYSGITAFKY----NHLKDKSVEEVVANIRDTLVEKGELAAGDLFVNTLSMPLHENRTNTIKLSRV 482
502 0.000e+00UniRef50_A0A160T3V9 Pyruvate kinase n=2 Tax=Chloroflexi TaxID=200795 RepID=A0A160T3V9_9CHLR  ali  35  1.................MARTKIVATIGPGSAHPETIRRMLAAGMTVARVNFSHGDHAAHTKTVAMLREVAKT-EGKILAILGDLQGPKLRLGHVKAGG-MMLAPGDEIVLTPRP-----GQPAMIHLPHPDLIAAAMPGNRLVIGDGEVEFTVAEKRSDT-LRCLVTVGGLLESRKGVNAPGVDLPISCLSEKDLIDLELICELDFDYIALSFVRTVYDIQELRDIMESKKRQIPIIAKIEKSEAIDNLLAIRDAADGLMVARGDLGIEMPPQELPLLQKRIIAACNQVGKPVITATQMLQSMVEHPRPTRAEASDVANAILDGTDAVMLSGETATGKYPVESVMMMKQIAENIEHAFPYDQWRDR-RTAALLTGSVTEAIGGASCSIAEEVDAAAIASATLSGYTAQQIARFRPRIPIVAVSPSAYTQRRLALVWGVETLLVPDFTA------TDTMLEETARALRNSGL-EAGRRVVITAGVPFKSGHTNLIKVHTI 468
503 0.000e+00UniRef50_A0A2T2V4M1 Pyruvate kinase n=1 Tax=Bacteroidetes bacterium QS_9_68_14 TaxID=1919111 RepID=A0A2T2V4M1_9BACT  ali  36  2.................LRRTKIVCTLGPASSSRETIREMVRAGMDVARLNFSHGTHDDHAANIRHVREA-ERAEGRSVALLQDLQGPKIRIGEVADG-SVLVHQGRELVLTTEE-LDGAGTAERVHIDHATLPRDVNAGGRVLIDDGMLELKVLDTGE-TEVRTEVVVGGPMRSRKGVNLPHVRTTTPSLTEKDVADLEFGLEQNVDLVALSFVRSGDDVRRVRERVREQSKSVSLVAKIEKPEAVDSIDGILEEADGLMVARGDMGVELPLAEVPSTQKMLIHKSMASARPVITATQMLESMIENPRPTRAEASDVANAVLDGSDAVMLSGETAVGEHPVRVVEVMSEIVEKADRYRSEPEETDGTYHDAGAERGTTESISFTACQVAEQVGATAIACLTNSGRTACAIARHRPDIPVYAFTNRERVVDRLGILWGTRAFAIP------FQDDTDQGVELVHDKLTERGLVESGDLIVLTAGMPPRRGRTNMIHVSRV 491
504 0.000e+00UniRef50_A0A1I2ABV5 Pyruvate kinase n=2 Tax=Nannocystis exedens TaxID=54 RepID=A0A1I2ABV5_9DELT  ali  39  6.............SLPPLRRAKIVCTIGPSSQD--QIGALISAGMNVARLNFSHGSYEDHTRVFQTIRS-EASARDIAVAVLADLQGPKIRVGKIPA-PGFELKVNDEFILSVDPESKVE--PGRVTVDYPHLAGEVKPGDRILMDDGALELRVTGV-EGADIKTSVVTGGMLTSRKGVNLPGVHLSLPSMTEKDKEDLRFALELGVDLVAISFVRQPEDVLAVRTMMEEFGRVVPIVAKIEKPEAVTNLKSILEVSNGIMIARGDLGVEIGPEEVPVIQKQGIELANRVGKLVITATQMLDSMIRNPRPTRAEASDVANAVLDGSDAVMLSGETASGAYPLQAVHTMDKIVRSIERQERYWREPSDLDLGHS-----TNAIARAAVVCCKSPDTKAIVTYTVSGGIARLVSDYRPRVPIFAFTPNPATYQALAVYWGVVPVLVSSPHGNSIFVDIDRLI-------LSRGMLARGDRIVITLGYPVKHKSVNLLKLHVV 477
505 0.000e+00UniRef50_A0A1F8UE31 Pyruvate kinase n=2 Tax=unclassified Clostridiales (miscellaneous) TaxID=39779 RepID=A0A1F8UE31_9FIRM  ali  40  1.................MKKTKIVCTIGPATESKEMLVQLIKAGMNVVRLNMSHGTHEQHGEKVEKVKEVREKLK-VPIAILLDTKGPEIRTHMMQDG-SVILKTGQKMIISMDEVL---GTNEKISVTYKNMAKDVNIGDKILIDDGLIEMVVLEKRDD-EIVVEVKNDAVLLDRKSINMPATKLHFNFISEQDKSDIEWGLTQGIDFIAASFIRRPSDVLELKQLLKDRAGHVKIISKIECQEGVQKFEEILALSDGIMVARGDLGVEVDMEELPSIQKMLIRRCNEVGKPVITATQMLESMKSNPRPTRAEVTDVANAIYDGTSAIMLSAESASGKYPIEAVEAMTRIALKTESLLEYNENFIDV----SDSGSITEAISSAAADMAEILGAHAIIAMTKTGSTANKVSKYRNRCSLVAVTDVESTYRQLALTWGAIPAL------SDTKVTTDEMMNEGIIKALETGVVEIGAKVVITSGVPHVSGATNMIKVHVI 469
506 0.000e+00UniRef50_A0A1Y6K3V7 Pyruvate kinase n=2 Tax=Anaerolineaceae TaxID=292628 RepID=A0A1Y6K3V7_9CHLR  ali  37  2.................HRFAKIVCTLGPSSETKETIRALVSAGMDVARLNFSHGSHEEHSKKIDIIRQLSSEM-GIPITILQDLQGPKLRVGKLPEGG-VELRAGDHVTLSSSKAYVPDDADIFIPFEIPDLHKCLQPGNHILLDDGYLEMEVTAI-SGERIDAVVILGGLLKSNKGVNLPGANLSTASFTEKDREDLIFGLNKGVDLVAISFVRSANDILTVREVIESEAVKTPIIAKLERPEALEDLESIMQAADGVMVARGDLGVEMPPATVPVAQKEIIACANAHGKLVITATQMLNSMIENPRPTRAEATDVANAIFDGTDAVMLSGETAAGKFPIESVEMMASIIQWSEKDLNKWSKFDYFATLSQQKDSL--SITRAAKELASDRNVAAIIVFTQSGRTARLMSKTRPDVPIFAFTPELRTYHKMGLYWGVTPIYVP------YADTLETMLKHVDTAIITATKLEKGQKVILISGFPVGA........... 467
507 0.000e+00UniRef50_E6PIH7 Pyruvate kinase n=4 Tax=root TaxID=1 RepID=E6PIH7_9ZZZZ  ali  34  2.............EPIMQKRTKIVATIGPASRERSVMRSLLVAGANVFRLNFSHGTPDEHAAVIRSARELADEL-GIHIAVLQDLPGPKVRTGGFAAGESVRLERGDRFDLYVDDRV---GGNEGVSVSYAALPHDVEVGKRIYLQDGSITLRIIEKDTEH-IVTTVEFGGDLRARQGINYPDGSLNIDAVTDRDLEYLAFGLEQQVDYVAVSFVRSVDDIDRVKKFMKERGKHVPVLAKIEKHEALEDIDRIIAAADGIMVARGDLGIEIPLEQVPLVQKDLIARCNRASKPVVTATQMLESMTANSRPTRAEVADVANAILDGTDAIMLSGETARGAYPTEAVRTMAEIAREIEKHYPHATLRD--RRLEKSEPTIASSIAEAATRASSELKIPFIVTGTTTGNTAHHIAAFRPSARVVALTPHRRVAQRLALVWGVEALLIDQYAS------IDVLLYVTERRMQEEGFVERGDLIAFTTGMPVGAGGTNVLKIHQI 476
508 0.000e+00UniRef50_A0A1Q2HXK1 Pyruvate kinase n=34 Tax=Bacteria TaxID=2 RepID=A0A1Q2HXK1_9CORY  ali  37  3..................RRTKIVCTLGPAVANKDAILGLVRDGMDVARLNFSHGDYPDHEQNYRWVREATDE-TGHAVGILADLQGPKIRLGRFEGDGKTVWETGEVVRITVDDV---EGTHERVSTTYKNLAQDAKPGDRLLVDDGKVGLVCLEV-DGNDVVCEVTEGGPVSNNKGVSLPGMNISVPALSEKDKEDLRFALRLGVDMIALSFVRSPSDVDLVHEIMDEVGRRVPVIAKLEKPEAVDALESIVLAFDAVMVARGDLGVEIPLEQVPLVQKRVIQIARENAKPVIVATQMLDSMIENSRPTRAEASDVANAVLDGADAVMLSGETSVGVDPHNVVRTMARIVRSAET-------MGSVPPLNHIPRTKRGVVSYSANDIATRLNAKAIVTFTTSGDTARRVARLHPDLPLLVFTPVQQVRSQLAVTWGVETFLCPDVYS------TDDMIRTVDEQLLAVDKYNPGDTMVVVAGTPPGSGTTNTIHVHQ. 466
509 0.000e+00UniRef50_A0A1W9H5B5 Pyruvate kinase n=1 Tax=Nitrospira sp. HN-bin3 TaxID=1827378 RepID=A0A1W9H5B5_9BACT  ali  36  1.................MRKAKIVCTIGPASQSPAMLHRLIESGMNAARLNFSHGTHDSHARAIAAI-RQAASHQGTAIAIIQDLQGPRIRVGVVAQEG-IEVKAGQTVRLRTADDRLLPSSPPEIPVTYPRLARDLRAGARVLINDGLIEL-VAERISDEVIDCSVLTGGTITSHKGINLPGTTVTVPAVTEKDRDDIRFGVEQGVDYLALSFVRGPHDIATARTLLEECGARIPIIAKIERAEAVAALEDILDCADGVMIARGDLGVEMGPEAVPILQKRIIVEANRWRRLVITATQMLESMTQAARPTRAEASDVANAVFDGSDAVMLSAETAVGAYPVEAVQVMDRLIRAAEDTTEPGVTVNAHPSGGKP--SPAEAISMAAVSAAGSVRANAIVAFTESGTTARLISKHRPASPLLAFTPSDAIRRQMALYWGVRPFPMSQGGPP------EAWLEEAEQRLAVEQLVRPGDVIAVVSGTMAGVGGTNMLKLHEI 478
510 0.000e+00UniRef50_A0A0S7WG44 Pyruvate kinase n=1 Tax=candidate division Zixibacteria bacterium DG_27 TaxID=1703423 RepID=A0A0S7WG44_9BACT  ali  35  1...........MSSPDNWNRTKIVCTIGPSSRPSEIMQRLIQAGMDVARLNFSHGTPKEHLRDFREIRKSARRL-GRIIGILQDLPGPKIRTGRLPN-REVELTAGKKFSLSTRRAM---GDNSRVQVNYKGLPNDVKKGTGIFLSDGNLELKV-EKTTPTEVHCQVVAGGILKEHQGVNVPGVRLNVDAFTPLDRQYLLLGLKAGFDFVALSFVREAADVKRVRRLTDTQGREVFIIAKIEKHEALDNLDQIIEVSDGAMVARGDLGIEIPLAEVPAAQKLIIDRCNRVGKPVITATQMLESMVEHPRPTRAEVTDIANAILEGSDALMLSAETACGSYPVEAVRVLNEVAGATERKPRQHQIPSE--EARSLHHQIADNLSLFACVMASNLGAKVIAAPTRTGRTARLVSRFRPHAPIVALSSNELIQRELSLSFGVIPLKIRKGLS------FDRLLEETKSILRENGLVEEGDRVVFLAGSPSEAGQTNLMLVEE. 475
511 0.000e+00UniRef50_V6F176 Pyruvate kinase n=105 Tax=root TaxID=1 RepID=V6F176_9PROT  ali  32  1.................MRRTKIIATLGPASSTPQAIESLFRAGADVFRLNFSHGSHADHQARYDTIRALEQKI-GRPIGVLADLQGPKLRVGKFADGK-IKLETGATFRLDLSPEL---GTSVRAPLLHPEVFAAMNVGTELLLDDGKLRLRV-EQHGGDFAETRVIVGGELSNHKGVNVPNVVLPISPLTDKDKADLDFAVDMGADWIALSFVQRPGDVLEARKLIARKGSRVRLLSKLEKPSAIDYLEEIVELSDAVMVARGDLGVECPPESVPILQKRIIKCCRSAGKPVVVATQMLDSMVHSPSPTRAEASDVATAIYDGADAVMLSAETASGDYPVDAVTMMDRIINRVEEDDQYTVITDASR--SQPENTTRDAISAAARQVAHTLKAAAVVTFTSSGSTTLRAARERPQQPIISLTSGIEVARQLALVWGAHCVPTQEVRSFA------EMVQTAAKAAQDESFAHPGDRIVITAGVPFGSGTTNILRVAEI 474
512 0.000e+00UniRef50_A0A2W1JHH5 Pyruvate kinase n=2 Tax=Acaryochloris sp. RCC1774 TaxID=1764569 RepID=A0A2W1JHH5_9CYAN  ali  34  24...................RTKIVATIGPASQSPEVLREMALAGMTVARLNFSHGSYEDHAQTVKLLRSLSQDL-DTPITLLQDLQGPKIRVGIL--EQPVELIEGEKLTLVPVPDFQQQ--PHTIPIDYPHLAEEAQLGAQVLLDDGLLELKIEAVSEA-AVTCQIIEGGWLKSRKGINLPSLALRLPSLTDKDRQDLEFGVAQGVDWVSLSFVRRPEDIQHLKQVLKELGAESKVIAKIEKPQAIDHLEAIVNACDGVMVARGDLGVEMRPEKVPRLQKRIIRLCNQRGIPVITATQMLESMMQNPRPTRAEVSDVANAIIDGTDAVMLSGESAVGKFPAKSVEMLARVAADVE-------VDAQFVNYPPTGTDETHALSEALNILDKTLDLRCIVAVTTTGYTAMLAAAERSKAPVIALTPQLETYHRLNLVWGVQPLYWERPM-----EPVETLIDQVQACLLERQLAAAGDTVLILGGIPSRARGTNFLKIHR. 486
513 0.000e+00UniRef50_Q5CSM7 Pyruvate kinase (Fragment) n=53 Tax=Apicomplexa TaxID=5794 RepID=Q5CSM7_CRYPI  ali  39  35...MDKICSPLADNDVTQRKTQIICTIGPSCNNVESLIGLIDKGMSVARLNFSHGDHESHFKTLQNIREAAKARPHSTVGIMLDTKGPEIRTGMLEGGKPIELKAGQTLKITTD--YSMLGNSECISCSYSLLPKSVQIGSTVLIADGSLSTQVLEIGDD-FIVCKVLNSVTIGERKNMNLPGCKVHLPIIGDKDRHDIDFALKYNLDFIALSFVQNGADVQLCRQIISENPSSIKIISKIENLEGVINFDSICSESDGIMVARGDLGMEIPPEKIFVAQKCMISKCNVAGKPVVTATQMLESMIKSNRPTRAEMTDVANAVLDGSDCVMLSGETANGAFPFDAVNVMSRVCAQAETCIDYPVLYHAIHSSVPKPVAVPEAIACSAVESAHDVNAKLIITITETGNTARLISKYRPSQTIIACTAKPEVARGLKIARGVKTYVLNSIHHS------EVVISNALALAKEESLIESGDFAIAVHGVKESPGSCNLMKIVR. 530
514 0.000e+00UniRef50_A0A2H0PK12 Pyruvate kinase n=1 Tax=Deltaproteobacteria bacterium CG11_big_fil_rev_8_21_14_0_20_45_16 TaxID=1973974 RepID=A0A2H0PK12_9DELT :_  ali  36  20.............ESIRLKRAKIVCTMGPSCQDPKILRQMIREGMDVARLNFSHGTHADHLRSIQSLRRIAKE-EGKYLGILQDIQGPKIRIGKFPKG-IVELRKNDEFIVRTDQVV---GSSRQISISLKNLHQHIEVGHRILLDDGLIFLVV-EKIRGRAIHTRVVFGGSLKDNKGVNLPDTRLKFSCLTPKDKKDIAFGLKNGVDFIALSFISEAQDIMKVRRLIKSQ-PDIPLIAKIETRQAVHNIEEIINVADGIMVARGDLGVECPLEKVPGLQKRMIRAANRKGKFVITATQMLESMTRSPRPTRAEASDVANAVLDGTDAVMLSAETASGQFPLESVKTMTRIIMRTEQ---YQQSFSDIQRLHESVTDIGHGVTAAAVHITSNLQASAIVAFTHSGATARYVSRLRPSPIIFALSPFEAICRRMAVVWGVIPGIIRKM------KHTDEMPALSRPVLTEFKMWRKGTRFVMLSGTPVKPGTTNLVKVHEV 494
515 0.000e+00UniRef50_D8EVX7 Pyruvate kinase (Fragment) n=2 Tax=delta proteobacterium NaphS2 TaxID=88274 RepID=D8EVX7_9DELT  ali  39  1...............................SSRKALKELIMAGMDVARLNFSHGTHEAHGKVANSLKSLSKSMK-RPIAIMLDLQGPKIRTG-LIKGGHLTVNTHDLLTITTREV---KGDSGIISTTYRGITKDLQPGDRILMDDGLIELKVQSKNK-TDLLCEVTNGGIIGEHKGINLPGITTGIHAVTEKDRKDLDFGLDMGIDYVALSFVRGARDVEILKRILKKRGADIPVISKIEKPQALDKLDEILEASDGVMVARGDLGVELSPEQVPVAQKNMIALANQERKMVITATQMLESMTEHPLPTRAETSDVANAILDGTDAVMLSGETSVGKYPAKAVKMMARIARVTERN------FPATPPFSRKTAGFSDTVSEAACLAAENLGLDAIVAFSQSGFTARLISKYRPPVPIIAFTTAETVQRSLALCWGVKSLLLPVM------DNSDVMIEMMEEQLRKKRLVKKNDRIVIVGGHPLNRGKTNMMKLHVV 452
516 0.000e+00UniRef50_A0A2W6AGX9 Pyruvate kinase n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A2W6AGX9_9CHLR  ali  37  19..................RRTRIVCTMGPACWQPETLRQMMLAGMDVARINFSHAEYESTARVITDLRTISTEL-GHNLAILADLQGPRIRMGRVP-EPGITLTPAAEFTLYSDPTTVP--TQSGAAVDYPALPEDVKAGDMILIDDGLLQLRVLATVPGQ-VHTQVINGGLLGSHKGINVPGVTLSAPTITYKDKADLAFALDHEVDAIALSFVRSPDDVAELRRLIAAHGARPLVISKIEKHEATDNFAAILAASDGIMVARGDLGVEMPAEELPILQKWMIKLTRAAGKPVITATQMLDSMMRNPRPTRAEATDVANAIFDGTDATMLSGESAAGLYPVLAVQTMARIAARAEQDYLTTPAAHTLATSDERGIGISQAVSHTIVETAMQLQAKAIVTLTRSGYTARQVAKYRPPIPVLAITSMPETYHQLAFTWGVTPCRIPSFTT------IDEMLIAAERIAVDAGVAQAGDTIVISAGLPLNPGRTNMLKVQVV 501
517 0.000e+00UniRef50_A0A1J5XC50 Pyruvate kinase n=1 Tax=Amphiamblys sp. WSBS2006 TaxID=1866961 RepID=A0A1J5XC50_9MICR  ali  44  7ISELEWFSNLSVEEKATEKKTGIICTVSPKVNSPEMLRKLHTRGMNIVRMNFSHGTHSDHLQTIENVKK-TFRNDKYPVALALDTKGPEIRLGEIKEGE-VTITKGQEVVLTTDGKYRKEGDRSCIFVDYARLPQVVARGSLIYIDDGILSLTVLECREDT-VRTEANNTHTISSRRGVNLPYTSVDLPAISEKDRADILFGVENNVDIIFASFIRKASDIATIRNILAENGKYIAVVAKIENHEGVQNIAEIIEEADGIMIARGDLGIEIEPEKVFTAQKKITTLCNRIGKPVICATQMLDSMIRNPRPTRAEISDIGNAVLDGVDCVMLSGETASGSYPLEAVETMRRVCMEAERAAPKEAQVGQLLKHSIERDGVLEAFARSVSMMTLHTKIAAVITLAMTGHSAGLIAKYRPKAPLIAVTRNEKISNTLLLRRGCIPFLYRPTAKADWDEEVQLRLRWAVRHAVELKIIGEDDLVLLVYGPKTGESENNTFRV... 502
518 0.000e+00UniRef50_A0A2M7AEU7 Pyruvate kinase n=1 Tax=Armatimonadetes bacterium CG07_land_8_20_14_0_80_59_28 TaxID=1973917 RepID=A0A2M7AEU7_9BACT  ali  35  1.................MRRTKIVCTLGPASESPETIEALIEAGMDVARLNFSHGDQGTHAACIRRVRDISQRL-GRAVAILQDLRGPKIRVGEIENGV-VEIKTGSDVVVTIRPV---KGTACLIPTSYASLPGDVQVGSQIKLNDGDIHLEVTRV-EDADVHCHVLDGGLLSSHKGINLPGVHVSAPSFTPRDQRDLQFGIASGVDYVALSFVRCPEDVAQIRKWIGEEMHCTPVIAKIEKPEAIHHLDAIMEVADGLMIARGDLGVETPLEGVPILQKEIIRKAAFTALPVITATQMLESMTHNPIPTRAETCDVANAVLDGTDAVMLSGETSVGEFPVETVQTMGKIIDAAERLMFSNQRFQDRAGAEHLGNFPA-AICEIAAHAAEDTGAKWIVGFTQTGSTAALLSKQKSPIPIVVFSHFPDIERRLSLLWGVLPRRMPPVA------DTESLVLQVDRALLAEGRVNPGDPLVIVAGAPIQKGHTNFLQLHRV 477
519 0.000e+00UniRef50_E1QGS0 Pyruvate kinase n=7 Tax=Bacteria TaxID=2 RepID=E1QGS0_DESB2  ali  35  1...........MNSLRDCRKTKIVATIGPVTASPAMIGHLVDAGLDVARLNFSHGDHDGHRQVISAV-RRAAAAAGRPVGVLMDLAGPKIRLGVLPLER--RLRTGQAVTLVQGESAEG----EAIPVNYPHLLEDVEIGGRILMADGLVELVVTGKKDGQ-LLCSVITGGEVSSRKGVNLPTSVLRIPAFTEKDRADLEMGLAEDVDFVALSFVRHEQDLAPVREILARREQPPLLIAKIEKPQAVERLDEILEAVDGVMVARGDLGVEMPLEEVPIVQKRIIDHARRAGKLVITATQMLRSMMTSPRPTRAEATDVANAVFDGTDAVMLSDETAAGNYPLDSVKVMDRICRAAERELDTAHYLRQELSSLLPATE--AALSRAAVYLARDLNAAGIVASTASGGTARLIARFRPRQPVIGLTPHQHTLRQLTMSWGVIPAEVAPFGS------IEEMLAATARWCKEHGLADKGDKLIVTAGLPLQVGSTNMAKVME. 473
520 0.000e+00UniRef50_C0QT06 Pyruvate kinase n=14 Tax=Bacteria TaxID=2 RepID=C0QT06_PERMH  ali  34  1.................MRRTKIVATLGPATSSEEMIEKLILSGVDVFRFNFSHGDHETHLQNLKKVRSISEKL-GKPIAVLQDLSGPKIRIGVV--EEPFYLHFEDRIRIVKEEVI---GNKERISINYPEVLDQLEKGSYIYISDGSIRLQVVDK-DDEGITAKVIVGGMVSSKKGVNFPNVRLNIPSITEKDKKDIKFAIEEDIDLIALSFVKTAEDVIQAKEIIRSYGGDTPLFAKIEKHEAIENIDRIIEEADGIMVARGDLGVEIDMEKVPVLQKMIIKKANEKGKPVITATQMLTSMVSSPRPTRAEVSDIANAVLDGTDAVMLSDETTVGKYPLEAVKVMERTICETEK------VYPFFTEKEHAPTDPSLSVAYASNSLAKNLNGKAIAVFTKTGRTVRNVAKFRPKCPVLALTHDEKTLRRLNIVWGVKPYMIIKEE-----KDTDRMLCEFIGKAYTEDY-RTDEIVITLIGYVGSPGSTNIIRIL.. 463
521 0.000e+00UniRef50_A0A1Q9D9C7 Pyruvate kinase n=1 Tax=Symbiodinium microadriaticum TaxID=2951 RepID=A0A1Q9D9C7_SYMMI  ali  43  230.............SDSFKRKCKIICTMGPCCWDVPMLVKLIDEGLNIARLNFSHGDHEGHGATVGRVREASKQRPDKPVAILLDTKGPEIRTGFFKEGGKISLKAGQDLKLVSD--YDFKGDETCIACSYKTLPTAVKPGQIILAADGSLSLKVKSTGSDH-VVTEVLNDIAIGEKKNMNLPGVKVELPVLQEKDKKDIEFGVPQGVDFVAASFVQDAGDVKLIRDTLGMRGRSVKIISKIENQEGINNIDEIIAASDGIMVARGDMGMEIDIEKVGLVQKMIIMKCNAAGKFVVTATQMLDSMERAPRPTRAEATDVLNAVLDGTDVVMLSGETANGKFPEAAVATMRRICEQAESTLDYKSLYLNMRQLVLKGMSAVESVCSSAVKACVDSKCPLIIALSETGTTARLIAKYRPEAPILCITASETNLRQLLAIRGVIPILTASFQG------TDSVIAKALTRAKEHNMVKSGDIIVAVHGQKEEPGASNLMKMVTV 715
522 0.000e+00UniRef50_A0A0P1AR05 Pyruvate kinase n=1 Tax=Plasmopara halstedii TaxID=4781 RepID=A0A0P1AR05_9STRA  ali  44  26..................RKTKIFCTLGPACWSQDGLGELIDAGMNVARLNFSHGDHVSHADTLNRLRGALASRPHKNIAVMLDTKGPEIRTGFLANKDKVTIQKNAILELTTD--YNFLGDETKIACSYPELPQSVQVGGSILVADGSLVLTVVEIKDD-SVVCRAKNTATLGERKNMNLPGCKVMLPTLTEKDEDDLNFGLMHGVDYIAASFVRTGQDIDNIRKVLGPRGRSIKIIAKIESQEGLENFDEILAKTDGIMVARGDLGMEIPPEKVFLAQKMMIRKANIAGKPIVTATQMLESMIKAPRPTRAECTDVANAVLDGTDAVMLSGETANGDYPTEAVGMMARICVQAEGAIHYDNVYQSLRNAVLEPLSTQEAIASSAVKTAIDIKAKMIVVLTESGATARLVSKFRPSMPVLVLTAMVSSARQAGFYKGVRARCMGSMIG------TESILYRATDLGKQYGWVQSGDNVVALHGTVARSGSTDMLK.... 500
523 0.000e+00UniRef50_B0SL88 Pyruvate kinase n=134 Tax=Leptospira TaxID=171 RepID=B0SL88_LEPBP  ali  38  6..............KIPKKRTKIICTIGPASANRETILNLIYAGMDLARMNFSHSTHEYHKEIFELLRECEQE-SGKSIGILADLQGPKIRTGKLGAGT-IELKAGDQ--IAINNKGDFLGNRDEIGCTYQYILNDIDVGHKILIDDGKLAFVVKSKSKEKAILETVI-GGVLKDNKGINLPGTPISAPALSEKDIEDLQFALSLGVDYIALSFVRRANDLEMARQFMKD--SYAGLIAKIERPEAIQNIEEIIDHCDGIMIARGDLGVELDTQYVPIIQKEMITKLNQRGKPVITATQMLETMIDNPRPTRAEASDVANAVMDGTDAVMLSGETASGKYPVETVKTMTSIIQAAEESEIYLSHLRSMNRTEFEVERT--ALGSAAESISRSIHAKAIINFTRSGYSSLLSSEFRPLNPIYSFTPFLGTARKMQLFWGVESYVMPMMDKFP------DMIAFMSKTLKSEGKLKSGDTVVILSGAPGSVAQTDFIQIHKI 477
524 0.000e+00UniRef50_B5M6L6 Pyruvate kinase n=14 Tax=Thermotogae TaxID=200918 RepID=B5M6L6_KOSOT  ali  37  1.................MRKTKIVCTVGPATENPDMLKKLIEAGMNVVRLNTSHDDLEHHRRRIRTVKKIREELA-VPITILLDLAGPKIRTGDFSSDT-VVLKKGDLFTLTTEDIV---GDDKRVSVSYKKLPSEVNSGDFILVNDGKIKLKVVETNE-TEIKTTVVNGGEITHRRGINVPGIDLGIEALTLKDKEFIKLGIEEGVDYFALSFVRKPEDVIEAKKIISSFGGSIPIISKIETVQALKRIESIAEVSDGLMVARGDLGVEIPVEEVPIAQKKIIRAGNKNRIPVITATQMLESMIENPVPTRAETTDISNAIIDGTDAVMLSAETSVGKYPIEAVSVMHKTALSTEKYIRAHPYLLQWTREDVVTDDHTDAICRAAWDISETLKIKLIVSSTYTGHTAINVSGFRPRSHILAVTPNKNTYHRLGMVWGVTPMLLE------LGSTIDEMVKIASEKARKLDLLDPGDNFIITAGVPLGANTTNMLKLER. 471
525 0.000e+00UniRef50_A0A136PFR1 Pyruvate kinase n=2 Tax=FCB group TaxID=1783270 RepID=A0A136PFR1_9BACT  ali  37  16..............PPSLQHTKILCTLGPATATKERIRQLILAGADAIRLNFSHSKYEVHRKLTEMTREVSAELE-RHIAIIQDLQGPKIRVGTLPDG-PVLLRPAERVILTTDAV---ASGDKRIPVQYKQLADDVRTGDSIFLDDGLLRLRVVAK-SGRNIACDVINGGLLKEHKGVNLPGVNVSEPSLTAKDRRDLEFGLSLGVDYVALSFVRSAKDIFDLKRLIAKHGKTTPVIAKIEKIEAIRELDAIIMATDAVMIARGDLGVELPSYEVPLLQKRIIRKCRELGKPVITATQMLESMVQNPRPTRAESSDVANAVYDGTDVVMLSAETSVGAFPVESVMTMNDILRSTESVVRFDPNWKRTTTGETETEMAENAVAVAACVLSSQVNASAILCLSYTGNTARTMSRQRPDAPIIVMTQDLDVCRRLCIYRGIYTVTIE------QPDDTEDAVSIMKRAAIEAGVVEEGDTVIITTGYPLDEKSTNMIVVDRV 490
526 0.000e+00UniRef50_A0A1V4X0H4 Pyruvate kinase n=2 Tax=Bacteria TaxID=2 RepID=A0A1V4X0H4_9DELT  ali  36  1.................MRKARIVCTLGPPTQTATALQSLVEKGMDVARLNFSHGDHRSHGSLIRKIRAVEKKLR-RPVAILQDLQGIKIRVGSLEGGKA-TLGKGQSVEIRAG---SDRGDGRCIYIDYPWLIQDARPGDRILLDDGLIQLQV-KTTSGDSIAATVFEGGVLKEHKGVNLPGMKVSAAFFTEKDRADLEFGISMGVDYVALSFVRSADDVKEIKAWMDARGVSVPLIAKIEKQEAIEDIDGILSEADGIMVARGDLGVEMPLEEVPVFQKMLIRKANDARKIVITATQMLDSMTRHSRPTRAETTDVANAVLDGTDALMLSAETSAGQYPFDSVEVMDRIISFTEERMGERVEAFSMPGREGLSFDFPGTVAEAASRAAGEMKARCILAFTMTGFTARLISKFKPDTPIIALSPDPAVVRRMKLYRGVIPYRVRKLSS------TDRMIEEVDRFTVGAGFAKEGDVIVLVAGHPIAAKSTNFMKLHRV 472
527 0.000e+00UniRef50_A0A1V4Z6N7 Pyruvate kinase n=1 Tax=Methanocella sp. PtaU1.Bin125 TaxID=1811677 RepID=A0A1V4Z6N7_9EURY  ali  39  10.................MRKTKIVCTIGPACDSQDKLEALVRAGMNVARLNMSHADHPAHERTIRNIRLVSGAL-DRPIGILMDLQGPKVRVNGIQG--TANLVPGQEFTLTTRDV---PGDSKEVNVPVKELPQSVQAGQTLLLDDGLLELKVDGITE-TDIRTKVVRGGELKPRKGINLPQSTLQIPSITEKDVKDLDFGIRQGVDMVAMSFVRKPGDVLDLRRMVEDRGADLPIIAKIEKHEGVKNIDGIIEVVNGIMVARGDLGIEIPMAEVPITQKMIISKCNARGIPVITATQMLDSMIRNPIPTRAEATDVANAVFDGTDALMLSGETAFGEYPVKAVETMARIAQYTEDSSYYKQVISA--KTPRPSASITDTVAEATFDAARNLGAQAIITATQTGFTARKVSRYRPQVPILAVTTDPKVINQLTLSWAVVPVRIGESR------DFDHLVDEAVRMCTDRGYVRTGDLVVITAGVLTGPGGTNIMKVHLV 478
528 0.000e+00UniRef50_A0A134AL61 Pyruvate kinase n=6 Tax=Firmicutes TaxID=1239 RepID=A0A134AL61_9FIRM  ali  39  1.................MKKTKIVATVGPASSSPDMLRALIEAGVNVFRLNFSHGNHESHREELAAIREAARA-TKTSIATMLDTKGPEIRTGDF-KEESVELTPGSSFSLYREERL---GDGEGVYQTYDNLYRDVKPGQKILIDDGLIALEVTSI-EGTTIHTKVLNGGVVSNHKGINVPGAQINLPALTEKDIQDILLAIEEDMDFIAASFIRKKDDILAIRDVLEQHGGDIKIIAKIENEEGIANMDDIIATADGIMVARGDMGVEIETERVPMVQKELIARSIAEGIPVITATQMLDSMIRNPRPTRAEVADVANAIIDGTSAVMLSGETAMGEYPLEAVKTMARIAEVTEPVLKEEEPYKHLTSFKK---STTNTVVQHAVEMADQLACDAIVIATATGYSSRNLSKFRPKTKVFAVTEDERVLRQMNLQWGVTGVLGSTRGKHIFDDTA--------RIVKRAGWIHDGDLIAMVAGIPQGAGSTNVIKIHQV 468
529 0.000e+00UniRef50_Q747D6 Pyruvate kinase n=63 Tax=Bacteria TaxID=2 RepID=Q747D6_GEOSL  ali  38  6..................RKTKIIATLGPVSSSPDMIRQLMDAGVDVFRLNFSHGSNDQRREVIAAIRRLSAER-GKEIGILADLQGPKIRTGRMENGA-IPLVRGDSLDITTDEVLGRPG---LISTIYQSLPHDVKPGSRILLDDGLIELRVQSV-SGATVRCTVVQGGMLKDLKGINLPGVKVSAPSLSEKDLRDLDFCLEVGVDYIALSFVRTAADVEGLKRILFERDVQVPVVAKIEKPEALRNFKSILKVADAVMVARGDLGVEISPEKVPLFQKKIIRACNEAGKPVITATQMLESMISHPRPTRAETSDVANAILDGTDAVMLSGETASGQFPLEAVRTMDKVALDVERFAQVEDGSGPRRHSVSIAEAVAEAACHAAVIL----KAKAVACMTQSGSTAARISRYRPPLPILAFTGSVDTMRRLSLYWGVKAYPIGTMAG------TDEQIVAVESTLLSGGY-RKGDVVVITMGVPVEAGSTNLMKVHK. 470
530 0.000e+00UniRef50_A0A1V2MC06 Pyruvate kinase n=2 Tax=Epulopiscium TaxID=2383 RepID=A0A1V2MC06_9FIRM  ali  42  1.................MQRTKIIATVGPKTRDEESIKKFINAGASAIRINFSHDNQAIHAGTAKRVMKIRKEL-GTPTALVLDTKGPEIRTGDIKNNGEIELIAGQTFTLTTDDI---EGSNDRISISYKELPHDLKKGDKILVDDGLIELVVREIVKN-DIVCTVKNGSILSSRKGINIPNVSLNLPPLTEKDVSDIALGAKLGFDFIAASFIRKASDVIRIRNILEENGRGIHIIAKIENREGVDNIDSILQVADAIMIARGDLGVEIPAEEVPIVQKRLIRKANIAGKPVVTATQMLESMVRNPRPTRAEVSDVANAIFDGTSAIMLSGETAKGDYPIEALSMMVNIAIMAEKTPE----MYNLVYKSNQFVSMTHAMSHATCQAAKQLNAAAIVTVTKSGYTARAVAKFKPTAPIIACTPDERAYRQMNLVWGCSPHII-----TIDKEETDSVFAKGVLKAEEIGVAKQGDVVVITAGVPLGAGTTNILKVQYV 471
531 0.000e+00UniRef50_B8BZT7 Pyruvate kinase n=18 Tax=Stramenopiles TaxID=33634 RepID=B8BZT7_THAPS  ali  42  30..................RRTKIICTLGPACWDVSQLEELIESGMNVARFNFSHGDHDGHKACLDRLRQAAKNM-NQNVAVLLDTKGPEIRTGFFADGKSINLVKGEELILTSD--YAYKGDSKKLACSYEKLASSVNPGQSILVADGSLVLTVVSCDETTEVVTRVENNAKIGERKNMNLPGVVVDLPTLTEKDVDDINWGIKHDVDYIAASFVRKASDVLFIRKILAENGGSIKIISKIENQEGLQNYLEILQATDGIMVARGDLGMEIPPEKVFLAQKYMIREANIAGKPVITATQMLESMITNPRPTRAECSDVANACYDGTDAVMLSGETANGCYYRQAVEIMARTCAEAETSVNWNELYQSVRNSVRKRLSSSESLASSAVKTAVDVGAKVIVVYSESGATARHIAKFRPGMPVAVLTPSEQVARQFGLLKGSYAFVVD------TLEDTHKLDKEVMRECRVAGIAQAGDPVVIVCGSTFGTGATNQIKVEFV 509
532 0.000e+00UniRef50_D3B0M1 Pyruvate kinase n=1 Tax=Polysphondylium pallidum (strain ATCC 26659 / Pp 5 / PN500) TaxID=670386 RepID=D3B0M1_POLPP  ali  41  358MATLSRNLRLQLDAPTQFVRTKIVCTIGPKTMSVEMLVKLIETGMSICRMNFSHGTHEYHGNVIKNLREAV-KRTGKGCALMLDTKGPEIRTGKLEGGQPITLPADHEILVDTNTDV--PGNTTRISLDYKGLIESVKPGGHILIAD------------------------VLGETKNVHLPGAVVTLPAVSEKDVNDIKFGIEQEVDFIAASFIRKAEDVLEIRRILGERAANIQIISKIENEEGITNFNDILEASDGIMVARGDLGVEVNMEKIFVAQKMMVSKCNAAGKPVITATQMLESMIKAPRPTRAEATDVANAVLDGTDCVMLSGETASGDYPIEAVDIMSKICREAESSTDYHTLFSALKVCSNKPITIAETIASYAVATAIDLKADIIITMTETGLTSRLVSKYKPPMPIFAITSWEYTVKHLLATRGTIPILVESLMG------TDKLIQHCLEIAMKQGLAKVGSRVVIVSGIMEGPGKTNSLRVLT. 846
533 0.000e+00UniRef50_X8K3K6 Pyruvate kinase n=16 Tax=Firmicutes TaxID=1239 RepID=X8K3K6_9FIRM  ali  36  1.................MRKTKIVCTLGPSSSNEETIRKMLLSGMNVARVNFSHGTHEQHHKTIETFRKVRDEL-DMPAAVMLDTKGPEIRLKDFVNGKEF-LEDGQEFTLTSRDV---EGTSSIVATTYERLPNMVKEGDKILIDDGMIVLTVISKTE-TDILTKVVHGGNVSNHKGVNIPDVDLGMEYIGEQDRSDILFGIEEDVDYIAASFVRMQEDVEELRKLLNDNGKDIKIIAKIESTQGVDNFEHILPKVDGIMIARGDMGVELAFERLPGIQKRIIKRCLESGKIAITATQMLESMVENPVPTRAEITDVANAVYDGTSAVMLSGETAAGKYPVEAVEVMAKVAEQAEAD-NETNYHEDRVWHEMNKRDVTNAVAHAACTLAEDINAAGIMAATNSGFTASRMSKFRPAKMIIGATPYTKAYHQMAMMWGVVPIKAK------YNAEVEELFDWFASEAVRSGLVEEGSKLVVTAGLPVEKGSSNMVRVI.. 470
534 0.000e+00UniRef50_Q2JSM3 Pyruvate kinase n=16 Tax=Cyanobacteria TaxID=1117 RepID=Q2JSM3_SYNJA  ali  38  1...........MHSSESFRRTKIVATIGPASSNPAILREMILQGATTLRLNFSHGDHDLHRRNIRLIRQTAMDL-GIQVAILQDLQGPKIRLGKFAEG-SITLRSGDPFVLTSKPIL---GSQERSWVTYDKLAQEVPEGATILLDDGRVEMRVEAVDEAGELFCRTIVGGTLSDNKGVNFPGVRLSIRAVTEKDKEDLYFGLNQGVDWVALSFVRDPSDVLELRELMAAVGKRVPIIVKIEKHEAIQQLPQILALSDGVMVARGDLGVELPAEEVPILQKRIIAMANCLGIPVITATQMLDSMAHSPRPTRAEISDVANAILDGTDAVMLSNETAVGKYPVEAVATMARIAVRIERDYFSPIYVDRRQHSPRPKTLVTDSISRAVGEIAQELDAVAVMTLTKTGATARNVSRFRPRTPILAVTPHVEVARQLQLVWGVRPLLVMDLPT------TRQTFQAAINVAQEEGLLKDGDLVVLSAGTLPGSGSTDLI..... 495
535 0.000e+00UniRef50_A0A2N1PNV6 Pyruvate kinase n=4 Tax=unclassified Bacteria TaxID=2323 RepID=A0A2N1PNV6_9BACT  ali  38  1.................MRRTKIICTLGPAVESDEMMKILIEAGMNVARCNFSHGDHQEHLGRIKTLRKVAAENR-HNVAILLDTRGPEIRTGEF-EGNSITLEKGQTVTLTSE---VIAGTAEKFTINYPRLAENVTPGIRILLDDGLVQLEVVNVIRAGDVICKVINSGTIKNRRGVNIPGIEVDLPNPTPRDLSDIQFAIDHDLDFIAVSFVQNARTILEIKKYLMQNGGDIKVISKIENQAGLQNFTSILNASDGIMVARGDLGVELPMEDVPLVQKDLIKKCFMAGKPVITATQMLHSMIHNPRPTRAEVSDIANAIYDLTSAVMLSGETSVGSYPIDCVSAMNKVAVRAENAIDYKGVYLSRLAMNSQDGDVTRAVTHAALTTAYEVGAKAIITCTETGYTAQMLSKTRPSMPIIAITSNEKVCKQLSLNWGVFPI------TGRSYKTLEEILKECIQLALDSKLIENGDLI---------AGATNLIKVEIV 474
536 0.000e+00UniRef50_A0A1A9I1W7 Pyruvate kinase n=116 Tax=Bacteria TaxID=2 RepID=A0A1A9I1W7_9BACT  ali  33  18...........TNTDHSFNRTKIVATVGPACNTYDKLLDLVKAGVNVFRLNFSHGVHEEKKQIIEYIREINRK-EKTAVAILGDLQGPKLRVGDMEGGG-ITVEPGDTFIFTNKKMV---GNKEKIYISYPNFHKDVKVGNKIMIDDGKLEVIVRKILPNNDVKVEVVLGGFLSSKKGVNLPDTKISLPALTPKDLQDLDFIMKEQLGWVALSFVRQVDDIKKLRKILDRNKSKAKVIAKIEMPEAIPNIREIIHASDGIMIARGDLGVELPVEKVPLIQKSIIRKCIHRAKPVIVATQMMESMIDRSKPNRSEITDVANAVLEGADAVMLSAETASGKHPTLVVQTMRKIILEIEKTEYHYDLSNELQPQPHSPSLSSDAICYNACNLAKDIMADGLIGMTQSGYTGFMLSSYRPKVPLYVFTKNLSLITQLSLSWGIRAFFYDDDQH-----DLDTIFSDQINILKKNGFLKRGDTVVSTGSTPVHLKRTNTIKVTDV 497
537 0.000e+00UniRef50_L1IAN1 Pyruvate kinase n=1 Tax=Guillardia theta CCMP2712 TaxID=905079 RepID=L1IAN1_GUITH  ali  43  10...................RTKIVCTIGPQTQSVDMLKKLYGAGMRCARMNFSHGSHEYHAQTIANVRSAMSEVKGI-CAIMLDTKGPEIRSGKLEGGEA-KVEQGTEFTLKYFPDVQNKGNSSWVAHDYANLHNVLDVGKEICIDDGLLSLTVLRI-EGTNVVCKVNNSVALGETKGINLPNTPVDLPAITEKDKSDLIFGVQQGVDLIAASFVRKADDVRDIRKVLGLPGRNIMIFSKIESQEGLDNFDEILAVSDGIMVARGDLGIEIPIQKVYLAQKMIIDKCNHAGKPVITATQMLESMIVNPRPTRAEVTDVANAVVQGTDCVMLSGETAKGKWPVECVKMMAEICRTAESSLDYVQEYLRMRQFKDRPNAVQESVASSVVKTALDIDAAILMALSHTGATARAVAKYKPSMPCFTITPSEQTARQLCLSRGVYPRVVGSMIGS------EQILAHNCSKLIKEGVISEGDICVCSHGDHSSPGSTSVMKVVV. 492
538 0.000e+00UniRef50_A0A1G4QXX7 Pyruvate kinase n=114 Tax=root TaxID=1 RepID=A0A1G4QXX7_9FIRM  ali  43  1.................MRKTKIICTIGPASDNEQTLTEMCRAGMNVARLNFSHGTHEEHQKKIDLIKSVREKL-NYPLPIMLDTKGPEYRIRTF-KDKKAELKEGQKFTFTVADV---EGDETRVSVSYKNLISELSVGDTILVNNGLLVFEVEELSGDDAV-CRVVAGGVISDRKSMNFPNHVFKGPYLSEQDKSDLLFGIQNDVDFVAASFVSTKQDMVDVRTFLDENGKDIDIIAKIENRAGVNNIEEICEIADGIMVARGDLGVEIPFVEVPAIQKYLIKECRLLGKRVITATEMLESMIHNPRPTRAEISDVANAVYDETSAVMLSGESAAGKYPVDAVRYMAEIAEYTERNIAYENRFHRTEYVIRNNLD---AVSHATCAMAIDTRAKGIVISSLSGITVRMVSRFRCPVDIIGMTTNTKAWRKLNLSWGVTPVLSEEFPS------VDVMFYYAMRHAKEVFGLESGDNVVLTGGKAGDSGSTNTIRVETV 469
539 0.000e+00UniRef50_A0A2A5APM1 Pyruvate kinase n=1 Tax=Candidatus Cloacimonetes bacterium TaxID=2030808 RepID=A0A2A5APM1_9BACT  ali  34  1.................MRKTKIVATVGPACSSEESLKLLMNKGVNVFRLNMSHGEHEIVEGLITMIRSLNKELK-KNVGILMDLQGPKVRVGKFENDQ-IELENGQIFTFDQNEEL---GTNERVSTTYPTIYQDVKRGDQILLDDGKMEVRVLEV-SGTSVITKVIQGGILKNKKGMNLPEVTIGLPAITDKDMADLKFGVEHDIDYIALSFVQRYQDVVYLRNILKMHKRDIGIISKIEKLGAVEDLERIAKLSDAVMVARGDLGVEISPEKVPNVQKRIISICNRLGKPVITATQMLDSMENSPKPTRAEASDVANAILDGTDAVMLSGETAAGNFPAESVEMMRKIIIETEKEMGYDIRPFTYFDFDGGLD--QEAISYSTCQIAKAVNANLICCFTSAGKQALRVSKFRPQHPIIAVTYTEKTANKVSLYWGVVPIVLKESSSN----TLDDEIIEADHKLIDKKWALEGDKLIITAGIPLHSGSTNAIKIHSV 473
540 0.000e+00UniRef50_A0A2N5KKB9 Pyruvate kinase n=2 Tax=Actinobacteria TaxID=201174 RepID=A0A2N5KKB9_9ACTN  ali  34  3..................RRTKIVATLGPGTSTEEMIRELVRFGVDVTRLNFSHGGHEGHLRNAQTVREAAKAL-GRNVAVMQDVQGPKIRTGEVIGET--ELIAGNRVVIAPGDFL---GDASRLATSYEKIAEDVKPGHRVLIDDGLLELRVEEV-ENGEVRCAVMVGGPISSHKGLNFPDSSLSIKGLTEKDVEDLRFGIEEHPDWIAFSFVRTGDEVREIKERIREFGGNVPVISKIEKHEAIEDIEDILRASDGIMVARGDLAVELSAERVPIEQKRLVARCRRLGKPVIVATQMLDSMIRNPRPTRAEVSDVANAIFDRTDAVMLSGETAIGRYPLQSVKEMDRICRAAEEAINYGR--DIVASTDWGRGDVYDALTHAACELAEDLDLEAIVTSTQSGLSCIRAARFRPPNKILAVSPVEETVRMLAMVWGVTAV------SGNQRGGIEERYEEALQAARENGLVSEGDRVILTGGSLGAPGSTNMLKLHTI 471
541 0.000e+00UniRef50_G2LG22 Pyruvate kinase n=2 Tax=Chloracidobacterium thermophilum TaxID=458033 RepID=G2LG22_CHLTF  ali  35  1.................MARAKIVATIGPASRSPEILRTLLVAGINVARINMSHGNHEGHAEVIRSLRQLAAELQ-QPLAILLDLCGPKIRTGRLIGGEPVVLVTGNRIVITPEDI---PGNAERVSCSYGGLAYDAKPGDRILIDDGLIELSVTAVH-GSDVECLILNGGVLGERKGINLPSIPTSLPSMTDKDRDDLRFGIEQGVDYVALSFVRSAEDCRQCKNYIAALGAQTPLIAKIEKPEALNHLDEILDIVDGVMVARGDLGVEAETERVPIFQKEIIRHANRKGRIVITATQMLQSMVDNPRPTRAEASDVANAILDGTDAVMLSAESAAGKYPVEAVRTMRRIVEYTEEAFAGQQSWRAGSNKNLQGSSSLRALSEAAVFAAENVGARVIAVFTEGGKMARALALLRPKQRIAAITADVGVYQQLSAVWGIEPLLMPNPP------DMKDLFAEGVGLLLRLGWIEAGERLVVLAGKIKGLPVNNLVHLQRV 474
542 0.000e+00UniRef50_A0A1V6BV00 Pyruvate kinase n=11 Tax=root TaxID=1 RepID=A0A1V6BV00_9SPIR  ali  39  2................RLRKTKIICTMGPSTNDIEVIKQLLSAGMNIARLNFSHSNHEYHKSMIEKIRKASSE-TRIPVAILLDTKGPEIRTGNIKDGKTITLIRDKKIVLTTDEV---EGTENLLSVSYKKLPEEVGPGKHIYIADGLVDLEV-EKVVGNEIHCVVRNGSEIGSRKNVNVIGVKTSLPAITDQDEKDIIFGIGQKVDYIAASFMRKPSDVKEIRNILDRFNSPIHIISKIENEEGVENIDEIIRVSDGIMIARGDLGVQLKSEEIPIVQKRIILKCNKANKPVITATQMLDSMINNPKPTRAESTDVANAIFDGADAIMLSGETASGKHPVLAVKTMNDIAYFVEQSTEYYMKCKGYFGMYDGNNSAGEAIAKAAFVVASDIDASAIITPTVHGTTPKLISKYRPTQNIIAATTSEETQRKLLLFWGITPII------TNLVSDSDIMLNNALKSALKENYVENYDKVVFVAGIPINSPIMNLIKVHLI 475
543 0.000e+00UniRef50_A0A0S8J5J6 Pyruvate kinase n=1 Tax=candidate division Zixibacteria bacterium SM23_73_2 TaxID=1703426 RepID=A0A0S8J5J6_9BACT  ali  35  8...................KTKIVCTIGPASGSPKILEKLITEGMDVARLNFSHLDHETCLTYVQRIKEISKKL-NRPVGLLQDLPGPKIRIGGLYKD-FIYLKKGKDVVLTTKKII---GNEERLHVNIKRFPEKIEKGAWVYLSDGMLQLKVKKKDEN-ELLCKVEVGGELRSRKGINFPGFDLSISAFTSEDKKHLRFWLENDLDMVCLSFVQTPEDIEKVKKFAKKLGKAIFLIAKIEKRKALENIDQIISSADGIMAARGDLGVEIPIEEVPFVQKRLIHKCNRAGKPVITATQMMESMVLNRLPTRAEATDVANAILDGTDAVMLSEETAIGKFPTETVRMMAKICKVTEENPGTGQ--RKVFSRDEKEYSIAEVISGSAFSASRSLNLKYIITPTRTGATPRMVSKHKPDCWILAFTYDLKVVNQLSLSYAVYPILLKEVDKSEQAE------KAVFDYLLVNKFMKKGEKIAITSGVPFGPGSTNSLRILTV 475
544 0.000e+00UniRef50_A0A2S8SW01 Pyruvate kinase n=1 Tax=Abditibacterium utsteinense TaxID=1960156 RepID=A0A2S8SW01_9BACT  ali  36  5..................RRAKIIATIGPASQSPALMRALLQSGMDVARFNFSHGGPLVHAAHIQTLRDVARDLE-SPLAILQDLQGPKIRTGGLTAGA-VELIAGNSFTITTRPV---GGDEHEVSTTYQALPRDCRRGDSILLDDGNLSLRVESTNE-TDVQCVVVDGGILKTNKGINLPGVDVSAPALSSKDKHDVEWAISQKLDYVALSFVRRVEDVLELRKIVEGSMSSIKIISKLEKPEAIDNLDEIIAVSDGVMVARGDLGVEMQTEDVPLLQKQIIKRANEMGKIVITATQMLESMTTNPRPTRAEASDVANAILDGTDAVMLSGETANGAHPIEAVKVMSRIVAKMENST--EDGLGGPHHFTYEKDDFASAICQAAAYAAGHMGAKAIACFTEYGGTARKLAKFRPPAPVIAFTPHDFVVRQLNLAWGVRGQVISPSQS------TDEMIEKADVEMLKSGLVVKGDKIVVVLGAPVACGSTNLMKLHRI 473
545 0.000e+00UniRef50_A0A0A8WUF7 Pyruvate kinase n=12 Tax=Desulfuromonadales TaxID=69541 RepID=A0A0A8WUF7_9DELT  ali  39  6..................RRTKIVATVGPASCSKEMICNLVDAGVDLFRLNFSHGKNDEKTVTIQYIREVSKQRE-KQIGILADLQGPKIRTGRMENGA-IQLLKGDSLSITTRDLLGRPG---LISTVYKALPNDVRAGSRILMDDGLIELKVAAV-DGDTVHCTVIEGGTLKDLKGINLPGVNVSSPSLTEKDRQDLEFCLQAGVDYIALSFVRTAADIEGVKRIIYEHDMHLPVIAKIEKPEALRNFKAILKVTDAVMVARGDLGVEINPEKVPLFQKKIIRACNEAGKPVITATQMLESMISHPRPTRAETSDVANAIIDGTDAVMLSGETASGAFPVEAVKTMGKIALNVEKS--------ELWRVSHRPDGISNNISRAACHAAASLNAKCIAVLTQSGSTAALISKFRPQLPIIAFTPFPEIQRRLSLYWGVNSCVVGKLSG------TDEQINAVEDTLLANGF-RKGDVIIITMGVPIEAGSTNLLKVHK. 470
546 0.000e+00UniRef50_F4NVP7 Pyruvate kinase (Fragment) n=6 Tax=Eukaryota TaxID=2759 RepID=F4NVP7_BATDJ  ali  46  1..........................VGPKTQSVEMLGKLVESGMNVMRMNFSHGSHEYHAQTVTNLRKYLERTKPRVVAVLLDTKGPEIRL-VLVDHTDKKLLAGSKFTFHND--MTRLGDETQVATTYTSLPKTVKAGDRILVDDGLIGMLVDEVDDKSEVHCTIENDGFLGETKGVNLPGNVVDLPAITEKDAGDIRFGIEQGVDFIAASFIRKASDVLEIRKLIQ--GTGIKIISKIENQEGLENFDEILSVSDGIMVARGDLGVEIPVEQVARFQKMMIRKCNTTGKPVVTATQMLESMIVNPRPTRAEATDVANAVLDGSDCVMLSGETAKGSFPVNTVEMMSKICREAEVDINYSELYPALRRQIRLPIGVSEAVAASAVKTSWDVHAALIIVLTQTGSTATRVSKYRPIAPVLAVTASPQAARQCQVLRGIYPLVVDSM------EGTENIIHCAMLWGVKMGMAQRGDAVVVTSGVLSTAGSTNIMRVLK. 465
547 0.000e+00UniRef50_A0A2G6NSK8 Pyruvate kinase n=7 Tax=Bacteria TaxID=2 RepID=A0A2G6NSK8_9DELT  ali  39  1.................MNFTKIVCTIGPSTQTEEKLFSIAEKGMNIARLNFSHGSHEYHLELIKKIRKTADTIK-KPVSILQDLCGPKMRIGKIV--KPITLSTGDKLFLTGSDA---DGTDNIVSVTYKDLPSDVKAGDILLLADGLLSAEVKS-SKNNKIECRIINGGILTSGKGINFRSGSLKAPSLTEKDKKDLLFGIKNKVDFIALSFVRKKEDILAVKEIIRENKSDIPVIAKIEKHEAVENIDEIIDVSDGIMVARGDLGVEIPLSLVPGVQKDIVKKANFKGKPVIIATQMLGSMAVSPFPTRAEATDVANAVLDGADALMLSEETASGNHPEKAVSCMSEIIMEAEK-------RYIPEKNQFHSDFVAESVAKAACTLADELDCDAVAAPTRSGFTAAQISKFRPSCPILAFTPNEAVIQRLNLLRGVFPFRFEE------VENTDIMIDNAAEKSIESGMVKKNGRIVITSGHPWKSGTTNMLQVRE. 463
548 0.000e+00UniRef50_A0A0B8XLY9 Pyruvate kinase n=32 Tax=FCB group TaxID=1783270 RepID=A0A0B8XLY9_9SPHI  ali  37  6..................KRTKIVATLGPATSNKDVLLSLIKAGVDVCRLNFSHGKAEDHQKVIDIIREINQKYK-TNVGILADLQGPKIRIGLVKDGG-INLINGTQIKITTNECI---GDDNQIYITYETFPQDVKAGEIILLDDGKLQMRVVETNRKDTVICEVLHGGILTSRKGVNLPNTKVSIPSLTEEDLVNLDFALANDVEWIGLSFVRKAEDIIDLKRIISRSGKTSRVIAKIEKPEAIDNIDAIIEVTDGVMVARGDLGVEMPMEEVPVLQKMIAQKCNKASKPVIVATQMLESMITTPRPTRAEVNDVANSVLDGADAVMLSGETSVGEFPLIVIETMSKIINHVENTSY--PYYKNKELDESCPTYMADAVCSSAVFLADKTNAEGIVAMTSSGYTAFQICSHRPKAGTYIFTSNRNLLNTLSLLWGVRGFYYDKF------DSTDTTISEVNKILKAEKLIESGDIIINTASIPIKKGKTNMIKVNVI 475
549 0.000e+00UniRef50_Q2S3S2 Pyruvate kinase n=6 Tax=Rhodothermaceae TaxID=563843 RepID=Q2S3S2_SALRD  ali  37  3..................RRTKIVCTLGPATTDPETLRRLVAAGMDVARMNFSHGTHEEHRERVETVREVAEA-EGKGITVLQDLQGPKIRVGAVQND-SVMLAEGDEVRVSTD--TPRESTNEHIFIDYEALARDAREGERILIDDGLLELRVIETN-GSQLRATVVEGGPLRSRKGVNLPDLQASTPPMTEKDLKDLELGLELEVDVVALSFVQERSDVEALVHRIEETGKKTSVVAKIEKPQAVHNIDEILEVVDGIMVARGDLGIEMPMEEVPGTQKRLIRKSMEAAKPVITATQMLESMVEDPRPTRAEASDVANAVLDGSDAVMLSAETAVGDHPVRVVEAMNQIIRQAESYWHERRALTMTPDHFEQGANVTNSVSFTACRLAEQVGAEAICCLTNSGSTARSIARHRPSMPIYAFTDNKRVVAQLGSLWGTEAFYIP------FQQDTDQGIARVHGVLHDYDLVRSGGHVVLTVGMPLPAGRTNTVHVSTV 475
550 0.000e+00UniRef50_A0A0B5QGX5 Pyruvate kinase n=300 Tax=root TaxID=1 RepID=A0A0B5QGX5_CLOBE  ali  39  1.................MQKTKMIFTIGPASDNEETLRKFIEIGMSAARLNFSHGTHETHKEKIELIQRLSKEM-NSATAIVLDIKGPKIRTHNFVNDG-VTLNDGDDFDFICGEEIL--GDEKRCSISYDVLYQDIKVGGKILVDDGLLKFKVTGV-EGKTIHTKVVVGGEIKNHKGVNVPNVVIKLPSITEKDIEDIKFGCKMGVDFIAASFIRKASDILDVKKVLKEHGEHIKVIAKIENQEGVDNIDSIIEVTDAVMVARGDMGVEIPIQKVPIIQKMIIRKCNEAGKVVITATQMLDSMIRNSLPTRAEASDICNAIFDGTDAIMLSGESASGCFPIEAAKTMSKIAQEAEEYLDYNHLTARLRE--PSLTDYAAAISYSACRTANILHAKAIVAATKSGATARLLSRYRSKAPIIAITPYEQVRKGLSLNFGIFPMPCK------MFNSTDEILTEAKNTVFSLNFTQPGDDIIVAAGMPTTQGGTNMLKIEKI 472
551 0.000e+00UniRef50_X6MYP8 Pyruvate kinase n=1 Tax=Reticulomyxa filosa TaxID=46433 RepID=X6MYP8_RETFI  ali  47  38.TQLIHNSQLDINTAHKTRRTGIICTIGPASQSVEMMQKLIEVGMNVVRMNFSHGTHQYHATTAENARAAAHKL-GIEICIALDTKGPEIRTGNFENDKVYVLELGKKVRVTTNDQYMNKGTAEQFYVDYKNITNVVKKVTLCMWMMGW-----------------------------VNLPNVPVDLPALSEQDRKDLAFGVKQKVDMIFASFIRSAEDVIGIRKELKEVGGRIMIIAKIENHQGMQHFDKILDVADGVMVARGDLGIEIPVQKVFLAQKMMVSKCNMKGKPVIVATQMLESMITNPRPTRAEVSDVANAVLDGADCVMLSAESAKGKYPIEAVTMMANICREAETARNSYEYFLQVSQSLKKPLGIPDTVALSAVQSCFEQQSQTMIVLTNSGTTARLVAKFRPPCPVIAVVGNTHTLRQLAITAGVYPIGYDDKQGKQSADD---RIELAISYAKKRQWAKTGGYIVAVHADKLNTGFANLIRILTV 510
552 0.000e+00UniRef50_U2T174 Pyruvate kinase n=23 Tax=Terrabacteria group TaxID=1783272 RepID=U2T174_9ACTN  ali  39  4..................KRTKIICTMGPATESDDVLRQLIASGMNVARFNFSHGSHDYHRNNIDRVRRISAEL-GMPVAIMLDTKGPEVRTGELKDHQKVMLKTGGTTV--VTTDDGVIGTAERFSLDYKELPNEVEKGSIILIDDGLIGLEVDHV-EGTDMHCVITNGGELGEKKGVNIPNVEVGLPSVTEQDRADIMFGCELGIDAIAASFIRNGAAVDEIRELCAENGRNLYILPKIESAMGVRNFDEILEHSDGIMVARGDLGVEINPAEVPHVQKTIIKKCNKAYKPVITATQMLDSMIHNPRPTRAEVADVANAIYDGTDCIMLSGETAAGQYPVEAVKMMASIAEETEKYLPETGEYHD----RGGLKNVNSAIGAAAVEVADRVNAKCIICPTHSGRTARLISNFRPKLPIYAMSPSNHAIRKTCFQWGVQAIKTTEQGS------LSATCYNALTVAKERGVVKTGDLVVITAGDPQTSPSTNMAMVSQI 479
553 0.000e+00UniRef50_A0A2A5DUI7 Pyruvate kinase n=1 Tax=Candidatus Hydrogenedentes bacterium TaxID=2030809 RepID=A0A2A5DUI7_9BACT  ali  37  2.............SAIHHRRTKIVCTIGPSTSSPEIMRELMVAGMNVARLNFSHGSHADHQSTCENLRKAAA-HTERNLGIMMDLQGPKIRTGKLTDGTPLHLNPGDPIAITTDDIV---GTQHRISTTYTELPNDVKSGDCIFLADGVLEFKVDRV-EDTTVHCTVVHGGHLGEHKGINLPGVNVSAPALTPKDIEDLEFGLEHDIDFVALSFVRTAEDIIDLKCRIEKSGRKIAIIAKIERPEALDNFDAILEAADCIMLARGDLGVEVPLHDVPQIQKELIGKCNDVGVPVITATQMLESMIGNARPTRAEVADVANAIYDGTDAIMLSGETASGDYPIQAVNVMANIANKSDTDLNTSPPHARIVRMRESAISYGDAVGQAACRTAHAIGAKRILCFTKLGYTAALIARYRPTVPITVVXMDESIRHRCSIIWGVDSELVVEPC------DTDNLDKLADTILLENNLAEPGDTVILAGGVPLAIRTTNMMKLHTV 484
554 0.000e+00UniRef50_Q6AII5 Pyruvate kinase n=8 Tax=root TaxID=1 RepID=Q6AII5_DESPS  ali  40  1.................MNKTKIIATLGPQSQSVEEIYSLIQAGMNVARINLSHGDAESYKHLISNVKEA-RKLAEKDTAILLDNRGPEIRVSEM--EEDIHLVDGEELVITNRAETV---SPSRITTNYPQLAGDVQVGSRILLDDGKLALEVLAI-EDEEVITKVIAGGILSSRKRVALPDNEVNLPSLSEKDKEDIAFGVEQDVDFIAASFVRQAGDVWAVRKIIEDNGGDQEIIAKIENRQGVNNLDEILQAANGIMVARGDLGVEVPAEEVPIIQKSIIKAANRLGKPVITATQMLESMITCPTPTRAEANDVTNAIFDGTDAVMLSGETAIGKYPVQAVAFLVRCATIAENALDYDHILANGLQNRRP--TITDSISYASCATAADLKATAIITATSSGSTARMVARYRPKAPVIAVSPSPSTIRHLQLIRGVTPLLC------NFGSSMDEQLDRVIHAATLAELIHNGDLVIITAGMPLGPGTTNMLKVHTV 469
555 0.000e+00UniRef50_A0A1J4UL20 Pyruvate kinase n=1 Tax=Candidatus Micrarchaeota archaeon CG1_02_55_22 TaxID=1805250 RepID=A0A1J4UL20_9ARCH  ali  38  3.................LRRTKIVCTIGPASESPERIAQLIATGMNVARLNMSHGSHAEQANRAKLVRAAAIK-QGKLVAILVDIRGPKMRVGRMRGG-FVNLSENTCVTLT---EKNIEGDGKTIPVDQAGFLKKIQAGNRIYLDDGALELEVISVGRGGA-ECNVVIGGRLKDRKGITVPGVSFDLESITAKDVIDIKFAASIKPDYVAQSFVKNADNVKEFRKRLDKNGCDASIIAKIEEPLGLRNIDEIIAIADGVMVARGDLGVQMPFEDVPLAQKQIVLKCHRANKPVIIATQMLESMINSPQPTRAEVADVANAILDGADAVMLSAETAAGNYPIRAVETMDRIALKTESSL----MVYDRVEKTRERLEPIEAIGKSVVYTARDLQASAIITYTSSGHTARYISSYRPSTPIIATTANERELRRLVLLWGVTPELVEKPTT------TDDLVKKSVNAALRNGRVKKGDVVVITAGIPLNPGNTNLLKIHRI 470
556 0.000e+00UniRef50_A0A0B6WS68 Pyruvate kinase n=8 Tax=Acidobacteria TaxID=57723 RepID=A0A0B6WS68_9BACT  ali  35  1.................MRRAKILVTLGPASREPAVLEAMLAAGANAVRINMSHGTQEEHAETIRRA-RAAAERMRRPLAVLVDLAGPKIRTGSLQDGKPVMLETNSLFTITTRPII---GNAREVSTNYAGMPRDVRPGTRILLDDGAIELYV-ERTTDTDVVCRVVNGGLLGERKGINLPGVSLPIPSLTEKDRQDLKWAIEQKADYIALSFVRRAEDCREAQALIRASGGRAPLVAKIEKAEAIDHLDEIIEAADGVMVARGDLGVETSVELVPVYQKQIIEKANIAGKFVITATQMLQSMVSNPRPTRAEASDVANAVWDGTDALMLSNETASGQYPVPAVATMARIIEAAE-MGRKGASHAREVWVGKGTQRVSRALCEASIFAAEEMRARAVAVFTESGLMARRLSSLRPQQRIIALTPSKEVQNELALIWGVEPVL------HAPCETTEQLVRAGERALLENGIVQPGELIVLMAGRLSGLGLSSSVKLHTV 471
557 0.000e+00UniRef50_A0A1H0RZ38 Pyruvate kinase n=1 Tax=Clostridium gasigenes TaxID=94869 RepID=A0A1H0RZ38_9CLOT  ali  41  1.................MQKTKMIFTIGPASDNEETLREFIKIGMSAARLNFSHGTHETHKEKIDLIKKVRSDL-NSPTAIILDIKGPKIRTHNFINDG-VEVKQGDEFIFICGSEIL--GNTNKCSISYEELYKDVSVGGNILVDDGLLKFQITEVI-GKEIHCTTIIGGMIQNHKGVNVPNVKINLPSITEKDKEDLVFGCQNGVDFIAASFIRKASDIDDVRKVLKANGGDIQVIAKIENHEGVNNIDSIIAVSDAIMVARGDMGVEIPIERVPIIQKSIIRKCNEAGKIVITATQMLDSMIRNSLPTRAEACDICNAIFDGTDAIMLSGESASGNYPLDAAKTMSKISIETEDNLDYNYLNKRLKEPALDAFS--EAISYSACRTSNLLNTKAIVAATNSGATAKLISKYRPKCPIIAITPHDEVRRGLSLNFGVFPLLCE------MFNTTDEIITEGKKVAKGSSFAKEGDDIIIAAGMPTTQGGTNMLKIEKI 472
558 0.000e+00UniRef50_A0A1C5N2B2 Pyruvate kinase n=31 Tax=Terrabacteria group TaxID=1783272 RepID=A0A1C5N2B2_9ACTN  ali  40  3..................KRTKIVCTMGPACDNDETLREMMKAGMNVARFNFSHGSYEEHHGRIERVRRIAAEL-DMTIGILLDTKGPEVRTGLLKDHQKISVKAGDKIVVTAAPSEDFLGDASHISLDYLDLPSEAEAGTRILIDDGIVELVVESV-EGQDMHCVVKNDGEIGERKGVNLPNVEIGLPAITERDRQDILFGLKEGIDYIAASFIRNGAAVREIRELCRENGGHVGIFPKIECALGVQNFDEILKASDGIMVARGDLGIEISPELVPHLQKKMIKKCNAAYKPVITATQMLDSMIRNPRPTRAEVADVANAIYDGTDAVMLSGESAAGKYPVEAVRMQASIAHETEQYLGAHAELK-VPEGSQSTRVINNVVGLSAVNMATTVGAKCIVVPTTTGRTARLISHFRPSTPVVAFSRHQWAVQKMLMYWGIEPHLA-----AITQGSVDDTVAKAIDCAKERGYVDAGDVAVVTVGDPIGDGSTNVVYVAQV 488
559 0.000e+00UniRef50_A0A1B0AGR6 Pyruvate kinase n=44 Tax=Hexapoda TaxID=6960 RepID=A0A1B0AGR6_GLOPL  ali  41  67.THLENTCRLDTRRAAHHRLTSIVCTIGAGSRNANTLKRMIISGMRIARLNLSHDSLEFHAETMRLIREASEAASKELAAIALDTKGPEIRTGLLEGNPEVEIKINDNLRLSINRDLMDKGNRECIYVDYPNIINVVQAGMLVFINDGSLKLIVKEVGVD-CITCQVERGGMLGSHKKVNLPGATVDLPAVSEKDINDLKFGVENNIDMIFASAMRNQDAVNELRDILKEKGREIKIISKIDCLQGLESIDKILNASDGILFSRNDVAIEIPSAKVFLAQKAVLARCNRAGKPVIVASELLESMRHRLRPTRAEICDLGNAVLDGADCVMLSSETAVGRYPVQSVQMLANIVQEAESALWYKNIFQDLLDRNPSSIDAAHSVAIAAVDASRKTLASAIIVLTTSGRSAHLMARYKPRCPILAVTRCNRSFRQCFLYRGIVPMLYSELPNTNWLADIDARIQYAMNIAKRINIIKTGDTVVIVSPWKDGSGFTNTMRLV.. 570
560 0.000e+00UniRef50_A0A192WQJ0 Pyruvate kinase n=1 Tax=Acidobacteria bacterium Mor1 TaxID=1660251 RepID=A0A192WQJ0_9BACT  ali  34  5...................RAKIAGTLGPASDNPRVLRKLVEAGLDVARLNFSHGGPEDHRRRVEMVRKVAARLK-HPVAVMADLQGPRFRLGVL--GQAQELKAGDGVTLCAGNQRIDKG---QIPVPFRALAGVVRPGHRILIDDGKVELRVSKVRQPR-IVCEVVRGGEISDRKGLNLPDTELPVPALTAKDKRDLKLAVELGADWLAVSFVRRPQDVRAARRLLARHGSNMPILSKIERPEAIENLEAILEESDGLLVARGDLGVELPPERVPVLQKKMIELCNYVGKPVMTATQMLDSMRYNARPTRAEASDVANAVLDGSSCLLLTAETAVGDYPVEAVSMMASITREAEKSGRVRVKLPDY-----ESLSVAEAASLAACRTARNVGARYVVAFTESGSTARAVSRFRPRTPILAFSPVQSVRRQLGLIWGVTP------RAAAKAKSIDSMFAELDRALLRGKMVERGELVVVLCGAPVGPGSTNLMKVHQV 468
561 0.000e+00UniRef50_A0A134CJ12 Pyruvate kinase n=11 Tax=Firmicutes TaxID=1239 RepID=A0A134CJ12_9FIRM  ali  40  52.................MRQTKIICTLGPCEENQDVLLALC--GMDVARFNFSHGSHESHLEMLQNLRKAAA-VVGRPIAAMLDTKGPEIRTGLLVNHQPIPLLAGHSIILTTQECV---GTEERVYINYDEVTKDIRVGHQILIDDGLIELKV-EKVDGNNIHCRIINGGELGERKGVNIPDIPIRLPALTEKDKEDLQFGIKEGFDFIAVSFVRNAECIEEIRNIITAAHSSMKIIAKIESKEGVAHFDDIVTAADGIMIARGDLGVEVDSKKLPQLQKEFIKKCNYEGKIVITATQMLDSMIRKPRPTRAEVTDVANAINDGTDALMLSGETANGKYPIEAATMMASIAEYTEQFLEHN-LFRYREMVQNIYDSVSNTTCRATVTAAHELHAKAIIAHTLSGHTALLLSKYRPDVPIYAFAPNETVIHQMMLFWGVHPILAP------YYSSTDNLFDRSIDMMKSLHHIRSNDICVVTAGVSSKKAATNILRIMQ. 526
562 0.000e+00UniRef50_A0A1C7MPU8 Pyruvate kinase n=1 Tax=Grifola frondosa TaxID=5627 RepID=A0A1C7MPU8_GRIFR  ali  61  8.SRIQWFSTLDTEETKFLRKTSIIATIGPNVNSVEKLTELRRAGVNIVRMNFSHGEYEYHQSVIDNTRKVAADPEGRPVAIALDTKGPEIRTGLMRDGKDIPIKAGHEFIISADPKYKTICDDKVMYMDYQNLYKVTAPGKLIYVDDGILSLLVLSI-DGENVRVRTLNNGTLCSRKGVNLPKTDVDLPALSEKDKADLRFG-----------------DVRDIREVLGPDGANIKIVVKIENEQGVVNFDEILKETDGVMVARGDLGIEIPASQVFLAQKMMIAKCNIAGKPVIVATQMLESMTYNPRPTRAEVSDVANAVMDGADCVMLSGETAKGSYPIQSVLMMAETCLLAEAAICYPPLYDELRAVTPRPTETVETVAIAAVAAASEQNASAIIVLSTSGNTARLISKYRP------ITRNQQTARQIHLHRGCYPFWYTEPRGYQWQTDVDNRIRFGLRNALKLNIIQTGSAVVAVQGWKGGLGHTNTLRILTV 493
563 0.000e+00UniRef50_A0A1F8J2W5 Pyruvate kinase n=1 Tax=Chlamydiae bacterium RIFCSPHIGHO2_01_FULL_44_39 TaxID=1797598 RepID=A0A1F8J2W5_9BACT  ali  40  4...................RTKIVCTIGPAVSSYEKILALIDAGMNVARLNFSHGSHKEHLQVINHLKKARKE-KNIPLAIMLDTHGPKIRVGRLPSGQ-ITLEPGQRVKLVVKESEKL----DEIPIHPIEVVDAMLPGMNILFDDGYIVSKVIEKTDKSAVV-EIQNSGVLKSGKGVNIPGAQIPLPALTETDIEDIKFGCKHDVDYIAASFIRSAHHVLTIKALLKQEKPDIQVIAKIESTQGIENFDSIVQVSDGVMIARGDLGVEVDLALVPKLQKMMIRKCYQACKPVVTATQMLESMIVNPRPTRAEVSDVANAIYDCTSLVMLSGETAIGKYPIETVQRMKEIVMEAEKDFDYQGFFRA--NSQKDYHDVSSAVSMAAVNTAYSANAKSIFAFTTSGGTARLVSRLRPPIPIIAVTPHEKNYHQLAFNWGVIPVLAKGC------KDSKESFAAASQFALERGLISFGDVVVVTAGEPFGKGTTNMMRVENI 471
564 0.000e+00UniRef50_A2C215 Pyruvate kinase n=32 Tax=Bacteria TaxID=2 RepID=A2C215_PROM1  ali  39  8..................RRTKIVATIGPATESASQISKLVEAGATTFRLNFSHGDHEEHAQRIKTIRKVSDDL-GIHIGILQDLQGPKIRLGRFKNG-PVNVKNGDKFILTSKNI---ECNQDQANVTYDKLAEEVNVGNRILLDDGRVEMKVEEVDKEQRLICSITVGGVLSNNKGVNFPDVQLSIRALTDKDKKDLAFGLKQGVDWVALSFVRNPSDLIEIKDLIRNHGYDTPVVAKIEKFEAIDQIDAVLKLCDGVMVARGDLGVEMPAEEVPLLQKQLIKKANSLGIPIITATQMLDSMASSPRPTRAEVSDVANAILDGTDAVMLSNETAVGDYPIEAVATMATIAKRIERDYPQKALESHL------PSTIPNAISAAVSSIARQINAAAIIPLTKSGATAKNVSKFRPPTPVLAVTNEKSVASTLQLVWGVTPLLIENQTS------TSKTFVDAMNMAKKMKILKQGDLVVETAGTLSGSGSTDLVKVGIV 474
565 0.000e+00UniRef50_W7TLB7 Pyruvate kinase n=2 Tax=Nannochloropsis gaditana TaxID=72520 RepID=W7TLB7_9STRA  ali  41  302...LDHV----LRENNAIRKSKIVCTLGPACWSVEGLGKLIDAGMNVARLNFSHGDHEGHGATLDRLREALATRPGVHVAVMLDTKGPEIRTGFLGSAKTVEYKKGSIVEIVTD--YSMPGNSEIIACSYSDLPTTTKVGATILVADGSLVLKVTELRS-SSVMAEVQNTAVIGERKNMNLPGAIVNLPTLTEKDVADLDFGIPQNVDFIAASFVRKGSDIDYIRSVLGEEGSHIKIIAKIENQEGLHNYEEILDRTDGIMVARGDLGMEIPPEKVFLGQKMMINKANIRGKPVITATQMLESMIKNPRPTRAECTDVANAVLDGTDCVMLSGETANGDFPTEAVTIMAKICREAESAMNYNQLSNTMRNTVMAFMGHPESVASSSVKTAFDIDAKMIVVLTETGNTAQLIAKYRPSMPILALTAIPETAR---FVQGVYCVVIGSMIG------TESILLRALDIGRQKGWVESGANVVCVHGTQEAPGSSNMLRVM.. 789
566 0.000e+00UniRef50_A0A2A6RMQ6 Pyruvate kinase n=1 Tax=Chloroflexi bacterium Kir15-3F TaxID=2024553 RepID=A0A2A6RMQ6_9CHLR  ali  39  1.................MRRTKIVATLGPASSSPERIAGLIRAGMNIVRLNFSHGSHADHAQLIADVRRAAAE-AGRPIAILQDLQGPKIRTGPLLEGQPVELLVGQRFTLTTEAV---AGTVERVSTTYQDLPHDVRTRDRILLSDGLIQLVVVERTA-TEVITEVVHGGWLKPNQGINLPGVRVSAAAATPKDFDDLAFGLAQGVDIVALSFVSRAADIVALKEVIRQAGRTTPVIAKIERPEALEVLPEILAVADGLMVARGDLGVEMEPERVPLVQKQLIDAANRAMVPVITATQMLESMIYNPRPTRAEASDVANAIIDGSDAVMLSGETAAGSYPIEAVQMMALIADAIEGRTAYETASASPRWAIPDVHSTPRALADAACTIARTLPVRAIAVLTQSGASARMVSHYRPRVPIIALCPSAETARRANLYWGVHPIQI---QVADRLEDLERQIQL---LLTNQGLMQSGDALVLTGGHPIYRGPTNFLKVLV. 475
567 0.000e+00UniRef50_I5C2W0 Pyruvate kinase n=6 Tax=Cytophagales TaxID=768507 RepID=I5C2W0_9BACT  ali  38  6.................FNRTKILATVGPASNSEDVLRSLAAAGANVFRLNFSHGNHEGHAAVIEKIRKINRE-TNSSLGILQDLQGPKIRVGEVENNG-VTIKPGDALTITSEEMV---GNSSMVSTVYQNLPNDVKEGDRILIDDGNLELRVNST-DGKQVHCTVIHGGLLKSRKGINLPNTKVSAPSLTEKDIEDLAFGLEQEVDWIALSFVRSAADIEDLRRRIQAAGKFCKIVAKIEKPEALENIDEIIAATDAIMVARGDLGVEVPMEKVPLWQKTMVEKCKLACKPVIIATQMLESMIVNPRPTRAETNDVATAVLDGADAVMLSAETASGNFPINAVKAMSTIIAHIEENAPIYHNLFKIPETDETFLS--NNLILMAVRLSRNVKAKAVVGITSSGFTAFRASAHRPSASIFIFTRNKPLITQLSLVWGVRAYYYESNVS------TDATFMDLQNKLKEDRHVVPGDIVVNTASMPLKAGKTNMLKIHIV 475
568 0.000e+00UniRef50_H5STC1 Pyruvate kinase n=1 Tax=Acetothermus autotrophicum TaxID=1446466 RepID=H5STC1_ACEAU  ali  39  3..................KRTKIVCTIGPASSSPETIRAMITSGMNVARINMSHGTHQEHRETIERVRAVAHSL-GVPVAVMADTKGPAIRTGELKTEK-VLLKQGQRLTLVEDPVL---GDETQISISYKGLSQHVRPGMKILLANGEIELTVLEVHPGR-IVCEVQNSRELGERKRVTIP--EVTLPGIAQTDEDDIRFAQHAGVDYIAASFVQTGLDIDHIRKLLGP--TDIEIIAKIETREAARNIDDIIAASDGVMVARGDLGVELPPEEVPLLQKEIVRKCNRAGKPVIIATQMLKSMTENPMPTRAEVADVANAILDGTDAIMLSEETAVGNYPVEAVRMMSRIAERIERSPAIYHRYE------MSEGTVAEAIGESACQIADRIGAAAIIPSTTSGSTAKLVAKFRPKTPIIAVTYTERVRNKLALVWGVYPVQV------TFFKDTDAMLKLSIEAAAKAGQLPSGSFVVITAGVPFGPGTTNLIKVERI 463
569 0.000e+00UniRef50_B3QUG4 Pyruvate kinase n=6 Tax=FCB group TaxID=1783270 RepID=B3QUG4_CHLT3  ali  38  1.................MKRTKIICTLGPSTDSIEKIVDLINEGMDVARLNFSHGTREEQEQRIQLVRKAS-ELTGKAVAILQDLQGPKIRIGDLA--KTVLLNQGEQLRISTEEQL---GNYEVVSTSYKEIVNDVNPGDTILMDDGRIELKVISKTA-TEVVTEIVIGGLLKPKKGLNLPGVNISIPSLTEKDLEDLDFGLAHDVDMVALSFVRSANDVKRIKQLIHEKNKDVWAIAKIEKPEAVANIDAIILESDGVMVARGDLGIEMRTEEVPVLQKMIVEKCSLAHKPVIIATQMLESMIENPRPTRAEANDVANAVFDGTDAVMLSGETAAGNFPVEAVRTMREIIERVEKQVRQKQWMQACSPRIRC-IDLDEAIAASAVQIAESLLAKAIIVLTHSGATAVKISKQKPKCAVIAVSDKEEVQRWMCMVWGINTIVTETMVS------TDESFRKIEKILRENGVVKTGDLVVYTLGIPIDHGGTDTIKVSHV 476
570 0.000e+00UniRef50_A0A2M7WER9 Pyruvate kinase n=2 Tax=Proteobacteria TaxID=1224 RepID=A0A2M7WER9_9PROT  ali  37  2...............PPHRHTKIVATLGPATDSPEMIEALLRAGVDLFRLNFSHSDHATHALLIATIR-LVEAYLQRPIAILQDLKGPEIRTRDVAD-TFRPLHQGEHVVLAPGPGPIQGTGP--LFITFEHLAEDVHEGQRVFIDDGSIALMVEAVM-GVEVHCRVERGGVLKSRKGVNFPGANLSLPFLTDKDYADLDFGIENGVDIVAASFVRSGSDVRRVRDYIRERGSKAMVMAKIETRQAVDNLEEVIREADAVMVARGDLGVEIPVEKVPMVQKRIIDLAVHLGKPVLTATHMLESMTHHAYPTRAEVTDVANAVLDGTDAVMLSGETANGEYPVESVLTMVRVIQEAEGVQRYQPAFQEWEP------DLASGIGRAACVLAQSLKAQAILCPTASGATARRIAMFRPERPIVALSVEPLVLRQLLLSHGVFPIRMRAM------ESLDQMVEDSHDLAVETGFVKAGDVVVQVFGLPVGAGSTNTIQVHRI 470
571 0.000e+00UniRef50_A0A0G4MEB0 Pyruvate kinase n=26 Tax=leotiomyceta TaxID=716546 RepID=A0A0G4MEB0_9PEZI  ali  63  355.....................................................HGSYEYHQSVIDNARAAEKAQPGRQVAIALDTKGPEIRTGNTKNDEDIPLAAGTILNITTDEQYATACDTKNMYVDYKNITKVIEPGRIIYVDDGVLAFDVLSIKDDKTVEVKARNNGFISSKKGVNLPNTDVDLPALSEKDKNDLKFGVKNNVDMVFASFIRRGQDIKDIRDILGEEGKHIQIVAKIENRQGLNNFPEILAETDGVMVARGDLGIEIPAAEVFAAQKKLIAMCNQAGKPVICATQMLESMIKNPRPTRAEISDVGNAVTDGADCVMLSGETAKGAYPNEAVSEMHEACLKAENTIPYVSHFEEICTLVRRPVSVVESCAMAAVRASLDLNAGAIIVLSTSGDSARLISKYRPVCPILMVTRNASSSRYSHLYRGVYPFLFPESKPDNWQEDVDRRIKWGINHAIDLNVLGQGETVVVVQGWKGGQGNTNTLRIVK. 804
572 0.000e+00UniRef50_A0A2D8C4V9 Pyruvate kinase n=28 Tax=root TaxID=1 RepID=A0A2D8C4V9_9BACT  ali  37  2...............SHINKTKILATIGPASNNYETIKSLAAAGANVFRLNFSHGTHDIHEEVIQIIRRVNEE-QNLNLGILQDLQGPKIRVGEVENNG-VEIKPGEPITITNDPVV---GTSRLVSTVYQNLPNDVVAGDRILIDDGNLEVVVNDT-DGKNVNCTVIHGGILKSRKGINLPNTKVSAPSLTEKDIEDLEFGLSQDVDWIALSFVRSPEDIYDLRERIQKAGKVCKIVAKIEKPEALENIDAIIDATDAIMVARGDLGVEVPMEIVPLWQKRMVEKCKLACKPVIIATQMMESMIQNPRPTRAETNDVANAVLDGADAVMLSAETASGKYPVNAVKAMSSIISYLEQNAEIYHNLYKIPEDDTTFLS--NNLLLMAARLSRNVKAKAIVGITSSGFTGFRIASHRPLANIFIFTRNKQLITQMSLVWGVRAYLYQNQVS------TDATFEDIEKTLKRDDHVSAGDIIINTASMPLKAGRTNMLKIHQV 473
573 0.000e+00UniRef50_C9M8I7 Pyruvate kinase n=4 Tax=Synergistaceae TaxID=649777 RepID=C9M8I7_9BACT  ali  40  11..................RKVKIVCTLGPASLADGVLESIVDAGLDVARLNFSHGTHEGHGQALQAVRRLEEK-KKQPIAVMLDTKGPEIRTTLLKNDEPVQLVPGQTFVLRPDD--GQPGDATGVGVTESNLAEECQVGQDVFIDDGTIHLIVREKR-DADLICTVDVGGMLGNRKGINLPGAELSLPSMSDRDKDDIIWGVRNGVDCIAVSFVRDRNDVLAVRRVVEEQGANTRLIAKIETKKAVENLESIADVVDGMMIARGDLGVEIPTEDVPLVQKRIIDLCRLRGKTTIVATQMLDSMIRNPRPTRAEANDVSNAVLDGADAVMLSGETAAGKYPLLAVQTMAKIVVRSEEELRRWQR----PLKVPVEAGVPDGVAMAAVEISRKLGASAVISLTKSGSTARLVSKYRPSCPIVATTPSVGTTRELCLCWGVVPVLCP------TASDGEQAVARAVEASLAAGLVNQGDLVVVTAGVPLDPGTTNLIQVQTV 479
574 0.000e+00UniRef50_J9K4X7 Pyruvate kinase n=6 Tax=Macrosiphini TaxID=33386 RepID=J9K4X7_ACYPI  ali  46  37.TALQYNCSLNIHNSHPLRRSGIICTIGPASADVKILEGLMDAGMNIARLNFSHGTHDYHLKTVENIRKAVKSYSNYPLAIALDTKGPEIRTGVLNGSKEIKLNKGDTLRLSTDKQYENKGSNKLVYVDYENITKILKENDRIYVDDGLILMKATKIGEN-YIDCIVENEGMLGSRKGINLPGVAVDLPAISEKDKADIQFAADNDLDMIFASFIRDRRAVTEIRNMLGERNKHMLIISKIENHQGIQNLQSIIKVSDGIMVARGDLGIDIPPEKVFLAQKSILAQCNIAGKPGICATQMLESMTKKPRATRAESSDVANAILDGADCVMLSGETAKGHFPIESVRTMDKICREAESAMWRKEFYHDMVASLAQRTSNDQNIMQAAVTAADNMSADVIIVIDQSGFIAHEIAIYRPRSIILLVTDNHRVARQCHLHRGILPVFYYPEIGEDFSNNWNKLRDYAIEFGKSLGIMKSRDTIVLVG................. 532
575 0.000e+00UniRef50_A0A2E9GD67 Pyruvate kinase n=6 Tax=Bacteria TaxID=2 RepID=A0A2E9GD67_9RHOB  ali  35  5.................FNKTKIVATVGPASNTKEKLHELIVSGVNVFRLNFSHGTHEQHQEVINHIRELNKTF-NYNVSILQDLQGPKIRIGTVENNAA-EIKEGDDFVITVEQEIV--GNSQRVSTTYTSLPRDVKAGDTILIDDGNLELRVYKV-EGLEVHTKVVFGGILKSRKGMNLPDTDISEPSLTKKDRKDLIFGLENDVDWVAISFVRKPGDVQELKSIIKDAGKASKVVAKIERPEAISNIDDIIDQSDAIMVARGDLGVEIQMEDVPMHQKRIVKKCNAKGRPVIIATQMMESMIENPRPTRAEANDVANAVLDGADAVMLSAETASGKYPVQAIQSMTKIIRAVESSADIYNKYY--QPDLNDPNYPSVILIESACKMASDTRAKAIVAMTNSGFTAFKLSRHRPEADIFAFTDNKSLLTTLNLVWGVRAYFYNKRHSTN------ATFKDMQEKLMKEGHLRKGNVFINTASMPFEAKKTNVVKIGIV 475
576 0.000e+00UniRef50_E1YJD2 Pyruvate kinase n=2 Tax=Bacteria TaxID=2 RepID=E1YJD2_9DELT  ali  36  4.................MPKTKIVCTIGPSSDSPEILEELILNGMNVARLNFSHGTHEEHLQKMNNIRAVSDKL-GAHVAILQDLCGPKIRIGKV-KEPGVRLDPGQAFTLTSR---IVEGDSEIVSVSYQSLSSDVKPDDRILLADGMLELVVKRI-SHTDIICEVITGGVLTSNKGINLPTGTIKADTLTYKDQRDLIFGLNNNVDYVALSFVRDADDIITLKNIIKKEMKNTPVIAKIEKHEALDNIEAIMEVSDGIMVARGDLGVEIPLETVPNIQKMLVKKANDMGKPVIIATQMLRSMVNSPRPTRAEANDVANAVLDGADAIMLSEETASGEYPVQAVQYMSKIAESAEENYPHEKYLNFL-----PKTDVSESVAYASCILAEHLDVKAIIATTRSGSTAIHISRFRPRSIIVALSPEKSTARLLALYWGCLPSLVTFIDDKCCSSDNSAL------SALASKYVSKGDLVVITSGTTEYAGTTNMMRVIK. 469
577 0.000e+00UniRef50_A0A0Q4QMP5 Pyruvate kinase n=28 Tax=Paenibacillaceae TaxID=186822 RepID=A0A0Q4QMP5_9BACL  ali  38  1.................MRKTKIVCTMGPACDSVDTLREMIRSGMNVARLNMAHGELEDHARRIERIREAAAA-ENAIVPILLDIKGPEVRIGKL-EEASYMLVAGETLTLTTEEVL---GNGRRIHVNYSELPLVVKPGNTILLDDGLIDLEVASV-EATEVHCTIVNGGLIKPRKGVNLPGIRTTLPGVTERDIRHIHFGIQQNIDIIAPSFVRRAEDILEIRELLQAHGGHVQIISKIENEEGVVNLDSIIAASDGIMVARGDLGVEIPVQDVPSMQRDMINKCNVAGKPVIVATHMLDSMQVNPRPSRAEVSDVAGAVMQGTDAIMLSGETAAGKYPVQSVATMAAIALKAESQLDYYAGFQERRQLAS--TTITEVISQAVVSSSLELKAKAILTRTESGFTARMVSKYRPQSPVIAITSDEKILPLLALIWGVIPV------KGTKTGTTDELLHAAMADAEQTGLLAEGDFVVITAGAPVGSGTTNLIKIEQ. 470
578 0.000e+00UniRef50_B9M7Q0 Pyruvate kinase n=9 Tax=Bacteria TaxID=2 RepID=B9M7Q0_GEODF  ali  38  2..............KTTFRKTKIIATLGPSSSSEKMITRLMDAGVDVFRLNFSHGSQQEKRALITTIRALS-DRKKVAIAILADLQGPKIRTGRMADGA-IRLVKGEKLDITTDEVLGRPG---LISTIYKALPHDVKPGSKILLDDGMIELKVVSI-SGNVVHCNIVEGGMLKDLKGINLPGVAVSAPSLSDKDRADLEFCLEMGVDFVALSFVRQASDVEGIKEIIRGKGLNTPVVAKIEKPEALRNFNSILAVTDAVMVARGDLGVELSAERVPLVQKSIIRACNEVGKPVITATQMLESMIVHARPTRAETSDVANAILDGTDAVMLSGETASGAYPIEAVRTMAKIALDIE----HAELWRIPAIKQVHSDNVPEAVAEASCHAASTLKAKALVVFTQSGNTAALISKFRPQLPIIAFTPFPEIQRRLALYWGVKSYPVGSVGGTRQQ------IKVGEETLMTTGF-RKGDLVVVSMGVPLEAGSTNLMKVHR. 470
579 0.000e+00UniRef50_K9ZCJ9 Pyruvate kinase n=26 Tax=Cyanobacteria TaxID=1117 RepID=K9ZCJ9_ANACC  ali  39  1.................MRRTKIICTVGPATSAPEKLEALVKAGMNVARLNFSHGAYEAHAQTFHHLRRISSDLQ-RPIAIMQDLCGPKIRLGKLPPEG-LMLEAGSEVTFLLQDK---GETIDELPLPLPTLFAMVRPGEPILINDGRVKLTVTSRDADK-IRAHVNIGGLVSTHKGVNLPATPLPVSSITEKDLMDLRFGIQLGVDWVAVSFVRSPQDLEPAKRMIEAAGAKIRLIAKIERAEAVEQLDAILNAADAIMIARGDLGVEVPIHQVPLIQKDITRRCNQAGKPVITATQMLESMISAPDPTRAEATDVANSILDGTDAVMLSGETAVGEYPIEAVQMMHNIAVQTETALKAGSRHSW--NHEAGCLSVTESVAQAVCRIAYETGSKAILCNTTSGNTARLISKYRPLTPIITLTSEAIAYRQLALSWGVEPLLIPPVHSA------EEMFMKVVNSVVEGGFAEDGDKVVITSGIPVGSGTTSLIKVHSI 470
580 0.000e+00UniRef50_A0A1V5Y5H4 Pyruvate kinase n=1 Tax=candidate division BRC1 bacterium ADurb.Bin183 TaxID=1852823 RepID=A0A1V5Y5H4_9BACT  ali  35  1.................MARTKIVVTLGPATDNLGIIRRLIEKGADVFRLNFSHGTPEEHARRIAA---IRKAAAGSPIAIIGDLCGPKIRCGRFANE-PATLKEGNPFILTAR---AIEGTDGAVSVSYKRLPREVKRGDAIFLDDGNIELRAEEV-SGPDIRCRVIRGGDLRSNKGINLPGTTLSIPALTPQDRRMIKFGVEQNLDYFALSFVKSPRDIYDARRLIRALGADTPIIAKIEKHEAVRDLEAIIEAADGALVARGDLGVEVPLEQVPLIQKRIIALCNRRAKPVITATQMLESMIEKARPTRAEAADIANAILDGTDAVMLSGETAVGKFPCEAVEIMDKIAQTAEENLDERRLL--MEQLLPEEGNIPDAISQATAQMARSLNASAILCCSITGYTARFVARYRPPCPIAVFTLNPKIQRRLQVVWGVVPILMKEMKGSRKRDGFDAIIREAVKETLRKQIAKRGDRVIVTAGLPLGVGGTNMLRVLEI 474
581 0.000e+00UniRef50_A0A0D2JBN7 Pyruvate kinase n=4 Tax=Bacteria TaxID=2 RepID=A0A0D2JBN7_9DELT  ali  36  2.................LRRTKIVATLGPATDSPEMIGKLIEAGLNVVRLNFSHGTHESHRQTIALVRRIAKEM-NRTIGILQDLAGPKIRLGDLAQGE-LEVQNGDTMVLKAGEASDDPG---IIPVGYPYLAEDVEKDERILLADGLVEILVKEIKDG-LVYCEVIVGGKLSSHKGINLPSSNLRVPSFTGKDKKDLALGLELGVDFVALSFVRHEKDLIQVREILNQVENPPLLIAKIEKPQAVDRLPQILAQVDGAMVARGDLAVEMRLEEVPLIQKRIIRLARKEGKPVITATQMLRSMMENPRPTRAEATDVANAVLDGTDAVMLSDETAVGSFPVESVAMLDRIAHYTEGKM---EDMDFEAQDTEVVPATEGSISRAACMLARELRAAAIVAATTSGSSARLVSRFRPKTAVIAITTSEEVQRQLALSWGVVPVLSPNY------DNTDQMFEQAKKDALNWGLAKGGDRLVITAGVPVGPGTTNLVKVM.. 468
582 0.000e+00UniRef50_A0A2P6V7Z2 Pyruvate kinase n=2 Tax=Chlorellaceae TaxID=35461 RepID=A0A2P6V7Z2_9CHLO  ali  41  363................PVNKSKIICTLGPVSRDVPTLCEMLRSGMNIARFNFSHGSHEYHQETLNNLRLAMRE-TRIMCAVMLDTKGPEIRTGFLEDEKPVVLEAGAELTITTD--YSIKGTKDLIAMSYAKLAQDVKKGSTILCADGSISLEVLETNAAGTVRARCLNTATLGERKNVNLPGVIVDLPTLTEKDIDDINWGIPNEIDLIAASFVRKGTDLDYIREVLGAKGQYIKIISKVENHEGVSNFDEILAKSDSIMVARGDLGMEIPTEKIFLAQKLMIQKCNLAGKPVVTATQMLESMTKSPRPTRAEATDVANAVLDGTDCVMLSGETAAGAYPIQAVQVMAKICREAEASIDYYSLFKAIMKRTPLPMTPLESLASSAVRTAHKVQASLVVVLTRGGATARLVAKYRPTVPILTVCSSEAPARQCLTSRGLVPILAEGSARASDSDTTDEILQAALEHAKDMKLCRPGDCVVALH----RIGNASVIKLV.. 852
583 0.000e+00UniRef50_K1L9J3 Pyruvate kinase n=84 Tax=cellular organisms TaxID=131567 RepID=K1L9J3_9BACT  ali  37  7..................NKTKILATIGPASNNYDTLYSLANAGANVFRLNFSHGDHAGHAEVVKMIRKINQE-TGLNIGILQDLQGPKIRVGEMENGG-VQISPGQKITITNDPVV---GNAELVSTVYKNLPNDVRQGDRILIDDGNIELAVNNT-DGKNVRCVVIHGGVLKSRKGINLPNTKVSAPSLTEKDLKDLEFGLEQDVDWIALSFVRSADDIRDLRDRILKSGKDCKIVAKIEKPEALKNIDEIIQATDAIMVARGDLGVEVPMETVPLWQKQMVSKCKLSSKPVIIATQMLESMTSHPRPTRAETNDVATAVLDGADAVMLSAETASGNFPVNSVKAMSSIINYIENNHDVFHHLYKIPEDDPNFYSKN--LTLMAARLSRNVKAKALIGITSSGMTALRLASFRPLANLIVFTRNIKLMTQLSLVWGVRSYHYESNVS------TDATFLDIQNQLKKDGYVKTGDIIINTASMPLKAGKTNMLKIHQV 475
584 0.000e+00UniRef50_A0A2W4WRL3 Pyruvate kinase n=5 Tax=Cyanobacteria TaxID=1117 RepID=A0A2W4WRL3_9CYAN  ali  39  5...............PSQRRTKIVATIGPATSSPEVLRELIEAGATTLRLNFSHGSHDDHLRSIRLIRQISYDL-NQPVGILQDLQGPKIRLGRFENG-PIVLKKGDPFTLTSR---LLPGTQEISSVTYDLLAEEVPSGATIMLDDGRVEMKVESIDRDQALHCRVVVGGPLSNNKGVNFPGVYLSIKALTDKDRKDLVFGLDQGVDWVALSFVRNPQDVLEIKELISSAGKAVPVIVKIEKHEAIEQMEAILSISDGVMVARGDLGVELPAEDVPILQKRLIATANRLGIPVITATQMLDSMVNSPRPTRAEISDVANAILDGTDAVMLSNETAVGNYPIEAVSTMVQIAVRIEKE-------EGKRLSEDAGRSIPNAISQAVGRISDQLGAGAIMTLTKTGATARNVSKFRPKTPILAITPHVDVARQLQLVWGIKPLLVLDLPSTW------QTFQAALNVAQEKDLVCEGDLVVMTAGTLQGAGSTDLIKVEVV 473
585 0.000e+00UniRef50_Q55863 Pyruvate kinase 1 n=129 Tax=Bacteria TaxID=2 RepID=KPYK1_SYNY3  ali  34  5...........INPVKFMRRTKIVATIGPASSSVEVIRQMVDAGMNVARLNFSHGSYEDHATMVRLLRSVEQEM-DTPITLLQDLQGPKIRIGQLPGGEK-QLREGEKVSLVPVEIGDR--HPGAVGIDYPHLATEAKVGERILLDDGLLEMKVVSIQ-DPEVICEVVTGGILKSRKGVNLPGLVLTLPSMTTKDKQDLEFGLSQGIDWVSLSFVRKGEDIHTLKQFLAERGPDLPVIAKIEKPQAIDNLEEIVAVSNGIMVARGDLGVEVNPEKVPRLQKEIIRRCNVRAIPVITATQMLDSMIQNSRPTRAEASDVANAILDGTDAVMLSGESAVGQYPVKSVQMLRKIAEETEVGLH-------LVNNPPIENTETHALSEALVVIDGILDLKYIVTFTTSGFTSLLASNQRPSVPVIAFTPSEKVYHSLNLVWGIIPFLINEE-----FDTFEDLIQQAEVLLRDRKMVEKGDQLLIMAGIPTKPRGTNFLKIHRI 482
586 0.000e+00UniRef50_A0A2H0JWL5 Pyruvate kinase n=2 Tax=Bacteria TaxID=2 RepID=A0A2H0JWL5_9BACT  ali  38  3..................RRTKIVCTLGPASDSEETIRALIRAGMDVARLNFSHGTHDYHRQIMERVRSASRA-EGRDVAILQDLQGPKIRIGEVEGGG-IDLVAGHSIRLTS--QVLATSTCDVLHVSYDTLADDLSVGGEILIDDGNIELKVVG-FDGRDVRAEVVTGGRLSSRKGVNLPNIRTSTPALTDKDLADLEFGLSQGVDIIALSFVREASDVKQLADRVRSQGSNVLIIAKIEKPEAVECIDEILATADGIMVARGDLGIEMRLSKVPGAQKSIIAKCLAAAKPAITATQMLESMIDNPRPTRAEVSDVANAVLDGSDAVMLSGETAMGSYPVRAVEVMRNIIVETEKTYLALHALD----PTGDTVDVTEAVSRSAYWMAAKVGAKAITCLTASGATARAIARHRPHVPVYAFTDDHRVVGQLALSWGTKAFFIP------FQCDTDEGISLVHDMLMDMGLAREGDRIVVTAGMPLPAKRTNMVHIST. 469
587 0.000e+00UniRef50_A0A2P6TI93 Pyruvate kinase n=1 Tax=Chlorella sorokiniana TaxID=3076 RepID=A0A2P6TI93_CHLSO  ali  42  398................PLNKTKIICTLGPACRDVPTLCEMLRSGMNVARFNFSHGSHEYHGETLANLRLAMRE-TKIMCAVMLDTKGPEIRTGFLENEQPVVLEAGHELTITTD--YGIKGNKDLISMSYAKLAQDVSKGSIILCADGSISLEVLETNKEGTVRVRCLNTATLGERKNVNLPGVNVDLPTLTDKDIDDLNWGVPNDIDLIAASFVRKGSDLDYIRSVLGPKGQYIKIISKVENHEGVSNFDEILAKSDAIMVARGDLGMEIPTEKIFLAQKLMIQKCNLAGKPVVTATQMLESMTKNPRPTRAEATDVANAVLDGTDCVMLSGETAAGAYPIQAVQVMAKICREAEASIDYYSLFKAIMKRTPLPMTPLESLASSAVRTAHKVQASLVVVLTRGGATARLVAKYRPTVPILTVCSSEAPARQCLCSRGLVPILAEGSARASDSDTTDEILHAALEAAKDMRLCRPGDCVVALH----RIGNASVIKLVDI 897
588 0.000e+00UniRef50_M4U686 Pyruvate kinase n=7 Tax=Bacteria TaxID=2 RepID=M4U686_9GAMM  ali  43  1.................MRKTKIVCTIGPKSESKEMLTKLVNNGMNVMRLNFSHGDFAEHGARITTIREICQE-TGKNVAVLLDTKGPEIRTVKLAGGNDVTLQAGQEFTLSTNQSII--GDNTIVAVTYADFANDLSVGNTILLDDGLIEMTVISIANG-DVLCRVENTGDLGENKGVNLPGVKVQLPALSVKDKGDLIFGCEQNVDFIAASFIRKKEDVLEIRALLKANGGNIQIISKIENQEGVDNFDEILEVSDAIMVARGDLGVEIAVEEVIFAQKMMIEKANAARKPVITATQMLDSMIKNPRPTRAEAGDVANAILDGTDAVMLSGESAKGKYPAEAVEIMATICTRTDAVMPSRAAVSNTN------LRITETVCNGAVNNAEQLNAKLIIVATGAGKSARSLRKYFPSATILALTSNPKTAQQLALSKGVLAQIIEK------QDSVEAFYTLGMNIAKELGLVEAGDKVVMVSGSLVPSGTTNTASVHVI 468
589 0.000e+00UniRef50_A0A257VD20 Pyruvate kinase n=1 Tax=Solibacteres bacterium 12-62-4 TaxID=1970571 RepID=A0A257VD20_9BACT  ali  36  1.................MRTTKIVATLGPASDSKEMIAKLFAAGVDVFRLNASHGVHEDHARRLRHVRELGQEL-NVPVGVLLDLQGPKIRLGLF-DGGKVLLENGADFEITTEECL---GSKERASTVYQNFARDVSPGDRVLIADGTVELRVLST-DGVSARCVVHAGGWIGDKKGINLPGVNVSTPSLTRKDMADLQWGIENRVDYVALSFVRKPTDVIRLRLYLEEKEHMLPIIAKIEKPEAWEQLNEILAESDGVMVARGDLGVEMAFEKVPFIQKSIIERARQTGKFVITATQMLESMIESPVPTRAEVSDVANAIFDGTDAVMLSAETSAGKYPVESASTMARIAVEAESSIRPRGYQDLPPRTNP---TIAEILADAAYHSARSANVAAIVVMTTSGSTARLIARYRPPVPIYAFTNSDIVARQLALIYGVRVLVTPTEPS------TEQMLAVMDRTLLDRGYLKARDTVILVAGQPWRSGTTNMMILHRV 469
590 0.000e+00UniRef50_A0A2H6F6J6 Pyruvate kinase n=5 Tax=Bacteria TaxID=2 RepID=A0A2H6F6J6_9BACT  ali  36  1.................MRKVKIVCTIGPASSSKNAIEKMIRSGMDVARLNFSHGDHEGHKKAVGHIRKAARKY-DSPVAVLSDLKGLKIRVGVIKNG-SVMLKKNSTVILTT---KQIEGSSERISISYRHLLKDVKTGDKILFDDGLLQLKIIGKEKAGLI-AKVMEGGVLKSRKGVNLPGTKITGAVFTKKDREDLEFGIKMGIDYAAMSFVRSKQDILKVKNWLKKHNADIPVIAKIENRQALENIDEIIDASDGLMVARGDLGVELPPENVPLIQKDLIEKCNAVMKPVIIATQMLESMTGHMTPTRAEAADVANAVLDGTDALMLSAETSIGKYPVESLKMMNRIVKVTEMRKPRSYGADVVKK------DFAHALAESACSSAMDIKAETIVAFSRSGFTALLVSKFRPGVPITGFTVSEEVRRRMNLFWGIRPYVMK------FPDNTDEMISESERVLLQRRIARKGDSIVIIASSPFAGGKTNIMKLHKV 466
591 0.000e+00UniRef50_Q8YTZ8 Pyruvate kinase n=14 Tax=Terrabacteria group TaxID=1783272 RepID=Q8YTZ8_NOSS1  ali  38  1.................MRRTKIICTVGPATSAPERLEALVEAGMNVARLNFSHGAYDFHAQTAQYLRQISADRQ-KPVAIMQDLCGPKIRLGTLPPEG-LMVEAGQEVTFVLQEK---GSSLDELPLPLPTLFAMVRPGEPILINDGRVKLIVTDRDADR-IRAIAKIGGLLSTRKGVNLPATRLPVSSITEKDLQDLRFGIDLSVDWVAVSFVRSPYDLEPAQRMIEAAGKTIRVIAKIERPEAVEQIDSIIDVADAIMIARGDLGVEMPIHEVPLIQKDIIRRCNQAGKPVITATQMLESMISAPDPTRAEATDVANSILDGTDAVMLSGETAVGQYPVAAVQVMHDIAVTTEKSL--QEGSKHCLSHEAGGLSVTESVAEAVCRIAYETGAKAILCNTTSGSTAKLVSKYRPTTPIFALTPDETAYHQLALSWGVEPLLTPPVH------NAEEMFMNLINTAVRTGLVHDGDKVVITSGVPIGSGTTSLIKVHSI 470
592 0.000e+00UniRef50_E3ECI2 Pyruvate kinase n=64 Tax=Bacteria TaxID=2 RepID=E3ECI2_PAEPS  ali  39  1.................MLKTKIICTMGPACDSIDLLKEMIQAGMTVARLNMAHGELEDHVKRIENVRQAAKEM-NTCIPVMMDIKGPEIRIGKL-KEASVLLKPGSQLILTTEEIL---GDEHRISVNYPDMPKDIKTGDRILIDDGLVDLTVTSI-EGTEMICNIVSGGILKPRKGVNLPGIHTTLPGVTERDVKHIQFGVEQRIELIAASFVRKGDDIREIREILKGHHAHVQIYSKIENAEGMENLDDIIEASDGIMVARGDLGVEVPIQDVPVMQKEMIDKCNLVGKPVIVATHMLESMQVNPRPTRAEVSDVFNAVMQGADVVMLSGESAAGKYPVESVRTMAAVAASAESQLDYQEQFD--KRRARQSTNITEVISQGAVSSSLELDAKAIITSTASGFTARMVSKYRPKAPIIAVTPNNTVFAKICLLSGVFPIKGDKVAT------TDEMFESSIRNALNAGYIQKGDTVVLSAGVPVEAGTTNLIRVYQ. 470
593 0.000e+00UniRef50_P34038 Pyruvate kinase n=1529 Tax=root TaxID=1 RepID=KPYK_LACDE  ali  40  1.................MKKTKIVSTLGPASDDIETITKLAEAGANVFRFNFSHGNHEEHLARMNMVREVEKK-TGKLLGIALDTKGAEIRTTDQEGGK-FTINTGDEIRVSMD--ATKAGNKDMIHVTYPGLFDDTHVGGTVLIDDGAVGLTIKAKDEEKELVCEAQNTGVIGSKKGVNAPGVEIRLPGITEKDTDDIRFGLKHGINFIFASFVRKAQDVLDIRALCEEANSYVKIFPKIESQEGIDNIDEILQVSDGLMVARGDMGVEIPFINVPFVQKTLIKKCNALGKPVITATQMLDSMQENPRPTRAEVTDVANAVLDGTDATMLSGESANGLYPVQSVQAMHDIDVRTEKELDTRNTLALQRFEEYKGSNVTEAIGESVVRTAQELGVKTIIAATSSGYTARMISKYRPDATIVALTFDEKIQHSLGIVWGVEPVLAKKPS------NTDEMFEEAARVAKEHGFVKDGDLVIIVAGVPFGSGTTNLMKLQII 476
594 0.000e+00UniRef50_A0A1V5W1S8 Pyruvate kinase n=2 Tax=unclassified Chloroflexi (miscellaneous) TaxID=189774 RepID=A0A1V5W1S8_9CHLR  ali  35  1.................MPLTKIVCTLGPATESPEVIRAMIRAGMTVARLNFSHGNVASTRQMAELVRRVARE-EKRFVALMGDLQGPKIRVGTLPEDG-VWLEEGHEVMLTSGPVGDP---QHEIPFPHPDIVFDLRMGDHILLDDGTLELEVLSVAPPAA-RCRVQVGGKLSSHKGVNLPGVALRLTAMTEKDCADAATALDLELDYLALSFVRSARDIEELRTYLKENPHRIPIVAKIEKPEALQDLEAIVRAADAVMVARGDLGVETAPERVPLAQKEIIRLCNRRGKPVITATQMLQSMIDAPRPTRAEASDVANAILDGSDAVMLSGETSVGKYPVEAVQMMARIAESVEASFPYNQLLDLPGDAEPAPRLISRAISRATVKIAEECSARAILTSTESGRTARTVARHRPRCPLIAATPFEQTARRLQLVWGVIPVPVAPF------DDTDSMIQTMVQAAVQLGYANVGDEVVLTAGIPFEVGVTNMLKVHTV 489
595 0.000e+00UniRef50_A0A2E5FJ47 Pyruvate kinase n=1 Tax=Solibacterales bacterium TaxID=2026791 RepID=A0A2E5FJ47_9BACT  ali  34  1.................MPSTKIVCTLGPASNSIDIIDQLLEAGMSAARLNFSHGTHADHAKTIANIRRISRKRQ-RFLPILADLQGPKIRTGKLVDGNPVELSPGKTLFISTSRI---AGNSHTIWVNYPGLARVLSKGDRILIDDGTIELNVVRV-DNRSIVTEVVHGGLLAENKGVNIPGLALKVPSLTRKDKVDLDFALEQAIDYIALSFVRTAQDIYKLKKRISAAQSPAHVIAKIEKPQAIDDIDAILAISDGVMIARGDLGVELSPWKVPVEQKNIIEKARLAKKPAITATQMLQSMIEQPSPTRAEASDVANAVLDGSDALMLSGETAIGRHPVETVRMMSRIIETTETTAPLPNRVES--QTSPQGDDLSEAVARSATFLAEDLGSKYIVVYTESGYTARLVSKYRPKCSVLGLSRHEAVCRRMKLLWGVRA------KQLGQVKDLDALVAKTQTILLSAGWVKKGDLISVVAGTPFRAGKTDVIKLHRI 471
596 0.000e+00UniRef50_A0A117LJS8 Pyruvate kinase n=1 Tax=Desulfotomaculum sp. 46_296 TaxID=1635262 RepID=A0A117LJS8_9FIRM  ali  38  1.................MKRTRIVSTIGPISGEISTLEKMMEAGLDIARFNFSHGTREEHLKRITAVREAAVR-TGKNIAILMDTKGPEVRLGRL--ERSVQLNAGQHVVLAPEGCQSGK---NYLPVSYVNLARDVKPGNKILLADGQIELKVISTRID-IVECEVIHGGEVSGQKGVNLPEVSLDLPFMSDEDRADIIFGIKHGVDFIALSFVHAEQDILTARKIMEKENSHAQVIAKIESREGLANLSGIIRFSDGIMVARGDLGIYLPIEEVPLVQKEIVKMCSEAGKPVIVATQMLETMINNPYPTRAEVSDVANAILDGADAVMLSGETAIGCYPVESVEIMNRIAERVENSLPYDEIWA--QKNKEIIHSITDAISHATVTTARDLGAAAIITSTQTGHTALMISKYRPNAPIIAVTPNKEVLRKMALFWGVQPLLIEPFQ------NTDQMINSSIKSSLDSGMVKSGDLVVITAGIPPDRGTTNFLKVHIV 469
597 0.000e+00UniRef50_T0P959 Pyruvate kinase n=16 Tax=Clostridiales TaxID=186802 RepID=T0P959_9CLOT  ali  44  1.................MKKTKIICTVGPTTDDKEIVKNLIKLGMNAARLNFSHGSHEEHKRRIDMVKEVRKEL-NRHTAIILDTKGPEIRTGKF-EGNTVELTEGTNFTIYAGEEIL--GDETKCSVTYNKLHEDVEIGDTILINDGLVALEVQSI-EGNKVHTLVKNTGVIGNNKGVNVPGVAINLPSLTDKDIADLKFGIDNEIDIVAASFIRKASDVLDIRKVLNKNGGDIQIFSKIENRQGVNNIDEIIKYSDGIMVARGDLGVEIPAEEVPVVQKNIIKKCNEAGKPVITATQMLDSMIRNPRPTRAEASDVANAIFDGTDAIMLSGETANGKYPVEVVKTMAQIAITAEEHINYEENLKKKRKSHIP--NVPNAISLATCNTAMDLKASAIITATQSGHTARQVSKYRPECNIIACTPYEKVARSLALNWGVYPILTPK------TETTDELIQNSAETC................................. 438
598 0.000e+00UniRef50_A0A1R1ML83 Pyruvate kinase n=5 Tax=Desulfurobacterium TaxID=64159 RepID=A0A1R1ML83_9BACT  ali  38  1.................MKRAKIVATLGPAVSDERVLERLVKEGLNVVRLNMSHGTHEEHKKRIRLVRKV-EENTKKPIPILVDLCGPKIRIGKIKDE-PLYLHRGNIIVLTSDKNYG----EDEVFVNYERLPEEVKPGEAILLADGAFRLKVKEI-DGKRVICEVVVGGPLTSHKGVNLPHTSLSIPALTEKDRKDVKFAVSAGADIIALSFVRKADDVLELKAMLDTLNSHIPVVAKIEKPEAVERIDEILDVADAIMVARGDLGVEMPIEKVPVIQKMLIRKANRKGKPVITATQMLKSMVDMPIPTRAEVTDIANAVLDGTDALMLSEETAVGKYPVEVIRTMSKVITEAEKMYPYR------RYEEIEPITLQDSLAKAACSLARNEQIKAIIPFTRTGATALAVAKFRPSVPVFAVTHDVKTSRKLALIWGIESCL------TVQVDSVEKMINVSVQAVKDRGIAKLGDKIIVLAGAPAGPGSTNLVKVVEV 466
599 0.000e+00UniRef50_Q1AXJ8 Pyruvate kinase n=3 Tax=root TaxID=1 RepID=Q1AXJ8_RUBXD  ali  36  2................RVRRTKIVATLGPATSSEESIGALVRAGVDVMRLNFSHGTHDMHLDNARTVREAAAE-AGRNVAIMQDLQGPKIRTGEVEGGT--ELVEGSRVVIAPGDFV---GDASRLSTSYDRLAQDVKPGHRLLIDDGLIGLRVESIKENGEIVCEVLEGGPVSSHKGLNFPDSSLSISGLTEKDLEDLRFGLEERPDWVAISFVRTGEEVLDVKERIRELGGDVPVISKIEKHEAIDNIEEVIEASDGVMVARGDLAVELSAERVPIEQKRIVARCRRRGRPVIVATQMLDSMMRNPRPTRAEVSDVANAIFDRTDAVMLSGETAVGRYPTQSVMEMDRICRAAEGAIDYGRDIAA--STAWGRGDRYDAVTHAACELAEVLEAQAILTSTQTGLSCIRVARFRPPNRILAVSPIEATVRRLALVWGVTAV------RGEQAGSIEERFRESVEAAEARGHLKKGDRLVFTGGTAGSPGSTNLLQVHTV 473
600 0.000e+00UniRef50_A0A143XQ72 Pyruvate kinase n=4 Tax=Clostridiales TaxID=186802 RepID=A0A143XQ72_9FIRM  ali  40  1.................MKKTKIICTLGPATDEEPVLMTMIQSGMDIARLNFSHGTKEDHHRRIAMVRRAGEKL-GVPVGVLLDTKGPEIRTGKMENG-SVTLREDTVVRVTTDDRM---GTAECFSVSYKPLPDEVKEGTLLLIDDGILRLKVEETGKD-YILCRVINGGELKSNKGVNVPGVKVNLPAITERDEEDIRFGLEEGIDFIAASFVRGREAVESIRAICDSAGKNVFIIAKIENEEGIENIDEIIDSADGIMIARGDLGVEIPAEEVPYLQKKIIEKCNFKMKPVITATQMLDSMMRNPRPTRAEAADVANAIYDGTDAVMLSGESAAGKFPVESVNMMAKIAEETEQHL--RGHLLERQRDIKSRVTISSTIAHMSVRAAEELEASCIIAATMTGTTARYLSNFRPPCVIAGVTPNEWVMRRMQLYWGVYPVKIREITT------TDDLILSAVEKTGRKSFVKDGDVCIMTAGIAAKENTTNMIRVFR. 471
601 0.000e+00UniRef50_A0A158RAN7 Pyruvate kinase n=1 Tax=Thelazia callipaeda TaxID=103827 RepID=A0A158RAN7_THECL  ali  47  35.TQLEHLSELDIGTPIRQRKTGIICTIGPACCEIQTLTNMIEKGMTVTRLNFSHGTHKYHAQLIENIRKACSSLNVNSIAIALDTKGPEIRTGILIDNNEIAIVKDSFVKLTTDTKYKDRCDSHLIFVDYPNITKVVQENSRIFINDGLISLVVKEIYE-SSINCIVEIGGMLGNQKGVNIPGATLDLPYVTDKDIEDLKFGVEQNVDFIFASFTRAARGIEIIRDVLGEKGKHIKIIAKIENEEGIRRLDEIIDAADGIMVARGDLGIEISASKVFLVQKMLIAKCNRAGKPVICATQMLESMVGKPRPTRAESSDVANAVLDGVDCVMLSSETAKGNYPLESLMTMHEICKEAETAFYYTKYFEELLRLVPKPTDDATTIAIAATSAVESCRATAIICVTVTGRTAELLSQWRPPVPIIAVCENSTVVRQLHLWRGVFPLHFEGWQ.................................................... 503
602 0.000e+00UniRef50_A0A1R3GIZ6 Pyruvate kinase n=1 Tax=Corchorus capsularis TaxID=210143 RepID=A0A1R3GIZ6_COCAP  ali  41  953...................KTKIVCTLGPASRSVEMIERLLKAGMNVARFNFSHGSHAYHQETLDNLRTAMN-NTGILCAVMLDTKGPEIRTGFLKDEKPIQITQGKNITITTD--YSIKGDENLISMSYKKLAEDLKPGSVILCSDGTITFTVLDCDKEGLVHCRCENSAVLGERKNVNLPGVVVDLPTLKEKDKEDIQWGVPNKIDMIALSFVRKGSDLVEVRKLLGEHAKNILLMSKVENQEGVANFDDILANSDAFMVARGDLGMEIPIEKIFLAQKLMIRKANILGKPVVTATQMLESMIKSPRPTRAEATDVANAVLDGTDCVMLSGETAAGAYPDIAVQTMASICVEAEKFINYGDLFKRIMETAPMPMSPLESLASSAVRTANCIKAALILVLTKGGVTAKLVSKYRPSMPILSLCSDEAPARHCLIYRGLVPVLSSGSAKASYDESTEESIKFALEYAKANGLCREGDSIVAL--------HPSVIKILTV 1437
603 0.000e+00UniRef50_A0A1G3PDT9 Pyruvate kinase n=1 Tax=Spirochaetes bacterium GWF1_31_7 TaxID=1802187 RepID=A0A1G3PDT9_9SPIR  ali  41  1.................MKKTKIVCTIGPSSEKPETIAKMLKAGMNVARFNFSHGDHVEKKHQMDVVKEAV-KLSGIPCAYLLDTKGPEIRTGNLKDGKKIQIESGANIVLTTDEV---EGTTEKISISYKNLPKEAKKGTLIYIADGVLSLEVVDI-KGNDIHCTIIAGGELGQKKNVNVVGVKTSLPAMAEKDKEDLIMGIKEGIDFVAASFIRKASDVLEIRKHLDANGGDVRIISKIEDEEGLENIDQIIEVSDGIMVARGDLGVQIKIEDIPLAQKKIIDRCNKAGKPVITATQMLDSMINNPRPTRAEANDVANAIFDGTDAVMLSGETAQGKYPVETVDTMARIARTVETSTEYLEHARAYFEFHKDTVGIGDAIAKAGYVVASTIKAKAIATPTMSGKTSRLISKFKPEQPIIATTVNERVMRQLLLDWGVFPILTGVAGES------EEMLNNCVKKVEELGFAGKGDNVVMLAGVPVKSHMVNMVRIFQV 474
604 0.000e+00UniRef50_I3II75 Pyruvate kinase n=4 Tax=root TaxID=1 RepID=I3II75_9BACT  ali  35  5.................FSRTKIVCTIGPACSSASMIEGLIHAGMDVARLNFSHGTLSEHEATIKNIRLVSQQL-NRPIAILQDLSGPKVRIKSLYKDA-ITLNADDVFTLTSKDV---EGNEKIASITYTCLPDIVFPGDTIFLCDGEIELRVVSKNS-TDIICQVIVGGILPSGKGINIPKRSLPIPSLTEKDKSDLEFGIEHDVDYVALSFVKNKDDILELKEIIRAKNRDIPVIAKIEKHEALNNLEDIIKTADAIMVARGDLGVEIPLEQVPLAQKKIIHLANSYCKPVITATQMLGSMVTNYRPTRAEVTDVANAIFDGSDAVMLSEETAKGRYPIASVIMLSKIANEIEPALVRKENFETL-RIPDSPITVPDAISIATCQVSNNLNTKVIITATQTGSTARFISKYRPKQHILAVTTSLHTYRRLALVWGVTPIVTEPIQ------NTDDMMKKSIEAAKQAGYIKEGEMIAFTGGVPWKPGSTNLLRV... 472
605 0.000e+00UniRef50_P22200 Pyruvate kinase, cytosolic isozyme n=186 Tax=Eukaryota TaxID=2759 RepID=KPYC_SOLTU  ali  40  12..........DLPNDGRIPKTKIVCTLGPSSRTVPMLEKLLRAGMNVARFNFSHGTHEYHQETLDNL-KIAMQNTQILCAVMLDTKGPEIRTGFLTDGKPIQLKEGQEITVSTD--YTIKGNEEMISMSYKKLVMDLKPGNTILCADGTITLTVLSCDPPSTVRCRCENTATLGERKNVNLPGVVVDLPTLTEKDKEDIEWGVPNNIDMIALSFVRKGSDLVNVRKVLGPHAKRIQLMSKVENQEGVINFDEILRETDSFMVARGDLGMEIPVEKIFLAQKMMIYKCNLAGKAVVTATQMLESMIKSPAPTRAEATDVANAVLDGTDCVMLSGESAAGAYPELAVKIMSRICIEAESSLDNEAIFKEMIRCTPLPMSPLESLASSAVRTANKARAKLIVVLTRGGSTAKLVAKYRPAVPILSVVSDETPARHSLVYRGLIPLLGEGSAKATDSESTEVILEAALKSAVTRGLCKPGDAVVALH----RIGSASVIKICVV 509
606 0.000e+00UniRef50_Q39ZF3 Pyruvate kinase n=37 Tax=root TaxID=1 RepID=Q39ZF3_GEOMG  ali  39  6..................RKTKIVATLGPASSSPEMISKLMEAGADLFRLNFSHGANDQRRETIATIRRLSAAR-GKEIGILADLQGPKIRTGRMENGA-ISLRKGDPLDIVTDEVL---GTPTLISTIYKALPHDVKPGSRILMDDGLIELKVHSV-EGNLVRCTVVEGGTLKDLKGINLPGVHVSAPSLSEKDLRDLEFCLAEGVDYIALSFVRSAEDVEGLKRILFERGIHIPVVAKIEKPEALRNFKSILKAADGVMVARGDLGVEISAEKVPLFQKKIIRACNEAGKPVITATQMLESMISHPRPTRAETSDVANAILDGTDAVMLSGETASGQFPLEAVRTMAKVALDVERY----AQMEDTLPQRRHNPSIAEAVAEAACRAAVTVDARAISVMTQSGSTAALISKFRPPLPIIAFTQSLETRRRLSLYWGVKPLPIGPMTG------TDEQIAAVESTFLSAGY-RKGDVIVITMGVPVEAGSTNLMKVHK. 470
607 0.000e+00UniRef50_I1CHV3 Pyruvate kinase n=7 Tax=Opisthokonta TaxID=33154 RepID=I1CHV3_RHIO9  ali  58  3.SNIQWLSRLNVDEPTHGRKTCIIGTIGPKSNSVETITQLRNAGLNIVRMNFSHGSHEYHKSVIDNTRKSVEIHPGHPVAIALDNKGPEIRTGNMKDDVEILIEVGHEMTFSVDDKYMDEGTSEIIYIDYKNLPKVIEVG--------------------------------------VNLPNSPIDLPALSAKDETDLKFGVQQKVDFIFASFIRRGQDIRDIRKVLGLEGKNIKIISKIENHQGVENFDDILAETDGIMVARGDMGIEIPLERVFIAQKMMITKCNLVGKPVICATQMLESMTYNSRPTRAEVSDVANAVLDGVDSVMLSGETAKGDYPVDAVKTMHDICKLAESVLCYPTVFHQLRHLTPLPTETMETVACAAVAAAQEQNAGCIVVLTTSGNSARLISKYRPNAPIVVVTRSQQTTRQIPLHRGCFAFYCPKASSEDWQEDVDRRIRWGLEQAMKNKLLKRGDPVVAVQGWKGGLGNTNTLRII.. 465
608 0.000e+00UniRef50_A0A2M6X0U4 Pyruvate kinase n=1 Tax=Bdellovibrionales bacterium CG10_big_fil_rev_8_21_14_0_10_45_34 TaxID=1973927 RepID=A0A2M6X0U4_9PROT  ali  35  6..................RRVKIVATVGPASNSQEMIQKLIEAGVNVFRLNFSHGSHEEHFQAIKYIRSASQELS-TPVAILQDLQGPKIRVGKLVGGK-MLLESGSTVVLTTRKV---SGENNVIPTDFEELPASCRPGQKILLDDGLLELKVLSVKQ-SDVECRVVYGGELKDRKGINIPGANLKVECLTEKDLVDLYFGLKHGVDYIALSFVRKGEDIRQLRTLIDEAGGFANIVAKIEMYEALENLNDIVQLSDAVMVARGDLAVEVGQSLLPGYQKEIIELSNTIGKPVITATQMLDSMVNNPRPTRAEVTDIANAVLDGSDALMLSAESASGKYPIKCVETMGEIIGEVERTGKYYYR----VNYEHEFFSIAEAIAAGSCLSALKLNASAIVCLTTTGKTARLISSFRPKCQILAVTHLLPTLNRLELVWGIQTLQIDPYNSS------DEAMERIEGMLLQFRLVKPGDRVILTMGLPIEQGTTNSLRVYTV 472
609 0.000e+00UniRef50_A0A2V2RIP5 Pyruvate kinase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V2RIP5_9BACT  ali  36  6..................RKTKILATLGPASSSAEMIEQLIHAGADGFRFNFSHGDHDFFRSLHQNVRNLSKKI-GRPVSILQDLQGPKIRTGKLQGGAAVELKKGKSLTITTR---QIEGNESIVSTTYAGLASDVQPGEKILIDDGAIELKVIRI-SKEDVETEVIIGGILKEKKGINLPGVKVSAPSVTEKDIDDAKFAIGLGIDYIALSFVRSAQDVVGLRNLLKSLNRDVRLIAKIEKPEAVENLVEILQVSDGVMVARGDLGVELPLERVPLIQKTIIEKANRVEKLVITATQMLESMVNHSKPTRAEASDVANAILDGTDVLMLSQETAVGQYPVRSVETMGRIAQHTESDHAVGSGFDHARQESVP--RFTHAIVRSAREAAEELQAKAILVFTESGVTAELMSDQRPHCPIYAFTSIEQTYLRLPLVWGVYPLFCD------LLEDTQLMIKNGEQLLVNSQQLNKDDVVVIVTGTHRAVGGTNILKIER. 474
610 0.000e+00UniRef50_UPI00098951A4 pyruvate kinase n=1 Tax=Tessaracoccus aquimaris TaxID=1332264 RepID=UPI00098951A4  ali  35  356...............CTVRRAKIVCTLGPSAETVDRLVELVNAGMNVARLNMSHGDYNEHGNRVKNVR-AASEITGKTVGVFADLQGPKIRLGRFADDAKIILEPGARFTITTDDIL---GDQERCSTTYKGLPGDVKVGDQILIDDGKVGMRAIEVT-DTDVVCEVTVAGPISNNKGINLPGVAVSVPALSQKDENDLRWALGQDVDMIALSFVRSADDIKRVHEIMDEEGRRLPVIAKLEKPQAIANLQEIIDAFDAFMVARGDLGVELPLEEVPLVQKRIVRAARKWAKPVIVATQMLESMISNPRPTRAEASDVANAVLDGADAVMLSGETSVGDYPVETVSTMARIVEKTE-----REGHAEIHTIDWDPHTTGGILAKAAAEVAERIGARYLVAFTKSGDTGRRLARLRSPIPMLVFSPEKSTRQQLTLTWGVDTQITPEFTEQ------EEMVEAVDHHLRDRGMIEVGERIVIVSGSPMGPGKTNNLRVHKI 825
611 0.000e+00UniRef50_UPI000A19CFFD pyruvate kinase n=2 Tax=Cyanobacteria TaxID=1117 RepID=UPI000A19CFFD  ali  36  7...................RTKIVATIGPASSSPEILKQMVNAGMNVARLNFSHGSYEDHARMVSLLRDVSEELE-TPITLLQDLQGPKIRVGQLPDGE-IPLTHGELLTLIPINEYSNQ--PNTASIDYPFLAEEAEPGAQILLDDGLLELRIEEI-KGQSVICKVVEGGILKSRKGVNLPSLDLRLPSMTEKDKKDLEFGLSQGIDWVSLSFVRKADDIRTLKSLLVQHNADVPVIAKIEKPQAIDNLEEIVEVCDGIMVARGDLGVEMSPERVPMLQKRMIQLCNFKGKPVITATQMLDSMIRNPRPTRAEASDVANAIIDGTDAVMLSGESAVGDFPIKAVEMLAKIAQDVEKDI-------EFPNAPPAETNETQALSEALNVIDHILDLQYIVTFTTSGYTSLLASKERPSVPVIAITPHEKIYHRLNLIWGVIPVLIDDE-----VDSFEDLVKQAETCLIQRNLALPGEQILIMAGIPTKPYGTNFLKIHKI 472
612 0.000e+00UniRef50_A0A146ZH18 Pyruvate kinase (Fragment) n=1 Tax=Fundulus heteroclitus TaxID=8078 RepID=A0A146ZH18_FUNHE  ali  44  42.NNLDHQRKLKLDLKITRRQTNIVATLGPSSHSVEDLKKLILAGMDVARLNFSHGTHEYHLESIRNLREAERTLNRQTVAIAVDTKGPEIRTGLVKN--PVDLVKGQPIHLTVNKMYEGNSDEHILYVNYSTLHQKVKVDQPIFINDGLIKLRVTNLTEEG-VDCVIEAGGELTSRKGVNIPGVSLDLPAVSEKDKEDLKFAVYNQVDFIFASFINNANQIVYIRKLLNDKHSNIKIIAKIESMDGLTNIDHIIRTSDGIMVARGDLGIEIPSEKVFVAQKMIVAKCNLEGKPVICATQMLESMTYNPRPTRAEVSDVANAILDGVDCVMLSGETAKGKYASECVHLMHQVAREAESCIFYKQGFDDRRFFATPPIEPNEAVAIAAVEASFRVFTPAIIVNTSTGSSAIRLSKYRPRALIIAVTRSIAVARRLKLYKGIISAVMSNNFTEHENSDTKERIEFGMEVAKKYGVVEIGDPIVVVFGWRLGPGNTNTIRIL.. 561
613 0.000e+00UniRef50_A0A2G6G6Y1 Pyruvate kinase n=1 Tax=Clostridiales bacterium TaxID=1898207 RepID=A0A2G6G6Y1_9FIRM  ali  39  1.................MRKTKIVCTIGPATNTEEKIRELINAGMNVARFNFSHGTHESHKKTMDLLKKVRKEM-GKPIGILLDTKGPDIRIGKVKENT--VLVPGKEFILTGDKKF-IEGDEKKVYISYKKLYKDVSEGDVLLIDDGLIKIVVKEIV-DKEIVTVVEVGGPLSTNKGINAPGIKINLPAITKQDIADIKFGVEQEVDFIAASFVRRKSDIIKIKGILEEENCHISLIAKIESRQGYENIDKIISVSDGIMVARGDLGVEMPIEEIPVAQKTIIRKCNTRAKFVITATQMLDSMIRNPSPTRAEVTDVANAILDGTDAIMLSGETAAGKYPIESVEYMHKIATLIEDSEDYEDIMGEIVN-TDTHDKLTYSISRSTAEMARKLEAAAIVTITSSGFTARRIAMHRPGCPIFAITTSEKNRRRLNLFSGVYTYIMD------YRGSMDQVFKKMVSFPLHDNLLQIGDLVVITCGVPFGVGTTNTMKVHIV 473
614 0.000e+00UniRef50_W0GX99 Pyruvate kinase n=11 Tax=Cyanobacteria TaxID=1117 RepID=W0GX99_9SYNE  ali  39  8..................RRTKIVATIGPATESPERIKELVKAGATTFRLNFSHGDHSEHAARIATIRQVSEEL-GQTIGILQDLQGPKIRLGRFAEG-PITLANGDPFTLTSRPV---SCDKTIATVTYNKLADEVTAGSRILLDDGRVEMKVDTVDKAQTLHCTVTVGGVLSNNKGVNFPDVQLSVRALTDKDKTDLAFGLSQGVDWVALSFVRNPSDMEEIRGLIREHGHETPVVAKIEKFEAIDQIDSILPLCDGVMVARGDLGVEMPAEEVPLLQKELIRKANSLGIPIITATQMLDSMASSPRPTRAEVSDVANAILDGTDAVMLSNETAVGDFPVEAVQTMATIARRIEKDYPQRSIDSHL------PSTIPNALSGAVSTIASQLNASAILPLTRSGATARNVSKFRPAAPILAITPDRTVACRLQLVWGVTPLVIP------QGERTTQTFQAAMVKAKELDLLKEGDLVVQSAGTHTGSGSTDLVKVSIV 474
615 0.000e+00UniRef50_A0A1J1JVF9 Pyruvate kinase n=1 Tax=Planktothrix serta PCC 8927 TaxID=671068 RepID=A0A1J1JVF9_9CYAN  ali  34  7...................RTKIVATIGPASKSPETIRQMVNAGMNVARLNFSHGSYADHAEMVKLLRLVSQEL-DTPITLLQDLQGPKIRIGQLPWEE-IELVEGEYLTLVPVDDFHNQ--PNTVPIDYPYLAEEAEPDAQVLLDDGLLELKIEEIQ-GNAVKCRIIEGGMLKSRKGVNLPSLILRLPSLTEKDKQDLEFGVSQGVDWISLSFVRRAEDVQALKALLAEKGAPIPVIAKIEKPQAIANLQSIINECDGLMVARGDLGVEMSPERVPLLQKQIIRMCNQRGIPVITATQMLDSMIHNARPTRAEASDVANAIIDGTDAVMLSGESAVGKFPVRSVQMLSKIASDVEPEI-------EFKNYPPVMSDETHALSEALNTIDKILNLHCIVAYTSTGYTAILAAAERPKVPVVALTPDRSVYHRLNLVWGVQPVLLE-----HQVNSFEGLIDLAQTKLLERGLAKIGDKILIVGGVPTKARGTNFLKIHTI 472
616 0.000e+00UniRef50_A0A1C5NCE1 Pyruvate kinase n=22 Tax=Terrabacteria group TaxID=1783272 RepID=A0A1C5NCE1_9CLOT  ali  38  4.............EKERKKKTRIVCTIGPASEDKKVLTKLVQAGMNVMRLNFSHGDFEEHGGRIKTLREINKEL-NKNVAILLDTKGPEIRTGDFVGGKT-EFKKGQVSTICVEDI---EGTSERFTITYKDLYKDVKPGGFILVNDGQVELLVDHV-DGTDIVCICANDGVVKNKRGINVPGIKLGFDYLSEKDIGDLTFGCQQGVDFIAASFVRRPQDVLDVKKLLIENGRPIQIIAKIENSEGVENMDEILKVADGIMVARGDLGVEIPAEDVPLIQKELINKCRAAGKIVITATQMLDSMQENPRPTRAEVSDVANAIYDGTDAIMLSGESAQGKYPVEAVETMTKIALKTEGTLDYASLQRKAIRTAS--LDQSEAICMSVAEIASKFNVAAIVAFTDSGFTARKMSRYRTKSMIIAATPNEQTTRALAINWGVKSVLCKQMDTRA------AMIEYAQVIAKEN-LVEPGEQIIVTAGTPGVAGTTSYLELITV 476
617 0.000e+00UniRef50_K7W6S6 Pyruvate kinase n=29 Tax=Nostocales TaxID=1161 RepID=K7W6S6_9NOST  ali  38  1.................MRRTKIVCTIGPATSSPEKLEALVRAGMNMARLNFSHGAYEAHAQVFHHLRQISKDLH-KPIAIMQDLCGPKIRLGKLPPEG-LMLEAGTEVTFVLQEK---GETIDELPLPLPTLFAMMRCGETILINDGRVKLTVTSRDADR-IRAHVNIGGLISSHKGVNLPATPLPVSSITEKDLMDLRFGIQLGVDWVAVSFVRSPQDLEPARRMIEGAGSKIRLIAKIERAEAVEQLDAIIAAADGIMIARGDLGVEVPIYEVPLIQKDIARRCNQAGKPVITATQMLESMISAPDPTRAEATDVANSILDGTDAVMLSGETAMGEYPIAAVQTMHNIALRTETVLQEGNRHSWSPKA--GSLTVTESVSQSVCRIAYETGAKAILCNTTSGSTAKLVSKYRPSTPIIALTSDCTAYRQLALSWGVEPLLIQPVH------NAEEMFVNVVDTVVDSGLVQEGDKVVITSGVPIGSGTTSLIKVHSI 470
618 0.000e+00UniRef50_A0A0B5QHW2 Pyruvate kinase n=713 Tax=root TaxID=1 RepID=A0A0B5QHW2_CLOBE  ali  43  1.................MRKTKMICTIGPASEDMEILEKVVLSGMNASRHNFSHGDHEEHGGRIKKVKELSKKL-NREIAIILDTKGPEIRTGKFEP-KKVELAKGSEFTVYAGD-MDVVGDTTKCSVTYAGLANDVKPGNTILIDDGLVGLTVKSV-EGNAIKCEVQNTGFVGTHKGVNVPGVSIQLPALTEKDKSDLIFGCEVGVTMIAASFIRKASDVKTIREILDANGGRILICSKIENQEGVDNLDEILEASDLIMVARGDLGVEIPIEQVPAVQKMIIKKCKAAGKPVVTATQMLDSMMRNPRPTRAEVSDVANAILDGTDAIMLSGESANGDYPVEAVATMAKIAEETEKSLEYKVAVSQAKTHIPA---IAGVISRAASNAANELEAAAVITSTQTGATAKRISQCRPECPIIAVTPDPIVARQLAFSWGVYPVVADKM------ESTDEMLERSVEIAKNNEFVKSGDIVVLAAGVPVDVGATNLLKISEV 472
619 0.000e+00UniRef50_A0A1Q3SIS8 Pyruvate kinase n=1 Tax=Chloroflexi bacterium 54-19 TaxID=1895928 RepID=A0A1Q3SIS8_9CHLR  ali  36  3..................RRTKIVATVGPACWDEAVMRRLIKEGVNVFRLNFSHAKRDQTSGIIDQIRRLAAE-ENHNVAILQDLQGPRIRTGEVDDSGSVTLVAGEETVLTTRPIKST--SPAEIAIDYKDLPLDVKPGDTILINDGLLELKVISSDS-EDVRCVIITGGPLSSHKGINVPGVTLRVPTITEKDKADLKFGVDKGVDYVALSFVRRGEDLFDLKNLIREYAGEPLVISKIEKHEAITNFDEILQASDGVMVARGDLGVEMPTEQIPVLQKMIIRRCNKVGKPVITATQMLDSMIRNPHPTRAEATDVANAIIDGTDAIMLSGESASGLYPVEAVRVMSRIANTTEESLLFKGTPKDILD--EGASSITDAISQAVCSIGREVKADAIITTTTSGFTARMVSRCRPKLPIFAVTHEERTVRRLALVWGIRSYLCPPY------ESTDEMLMMAEKVVVEKGLLSNGDRIVITAGIPVGAGQSNLLKVHIV 481
620 0.000e+00UniRef50_O65595 Probable pyruvate kinase, cytosolic isozyme n=161 Tax=Eukaryota TaxID=2759 RepID=KPYC_ARATH  ali  40  8...................KTKIVCTLGPASRSVPMVEKLLMAGMSVARFNFSHGSYEYHQETLDNLRQAM-LNTGMLCAVMLDTKGPEIRTGFLKDGKPIQLKQGQEITISTD--YDLKGDEKTICMSYKKLAQDVNPGMVILCADGTISLKVLSCDKEKTVRCRCENTSMLGERKNVNLPGVVVDLPTLTEKDKQDIEWGVPNQIDMIALSFVRKGSDLVQVRKLLGKHAKTILLMSKVENQEGVANFDDILINSDAFMIARGDLGMEIPIEKIFLAQKVMIYKCNFMGKPVVTATQMLESMIKSPRPTRAEATDVANAVLDGTDCVMLSGETAAGAYPELAVRTMAKICVEAESTLDYGDIFKRIMLHAAVPMSPMESLASSAVRTATSSRATLMMVLTRGGSTARLVAKYRPGIPILSVCSNEAPARHSLIYRGLVPVLYAGSARASIDESTEETLEFASEYGKKKQLCKTGDSVVAL----FRTGNAIVIKILTV 496
621 0.000e+00UniRef50_A0A2P4JQL8 Pyruvate kinase n=2 Tax=Fagaceae TaxID=3503 RepID=A0A2P4JQL8_QUESU  ali  39  1.........MEMEQKP---KTKIVCTLGPASRSVPMLEKLLRAGMNVARFNFSHGSHDYHQETLDNLKTAM-ENTGILCAVMLDTKGPEIRTGFLKDSKPIQLKLGQEITISTD--YSIKGDENMICMSYKKLAVDVQPGMVILCADGTISFKVLACDKKGLVRCRCENSSVLGERKNVNLPGVVVDLPTLTEKDKEDIKWGIPNKIDMIALSFVRKGSDLVEVRKLLGKHAKNILLMSKVENQEGVANFDDILANSDAFMVARGDLGMEIPIEKIFLAQKVMIYKCNIQGKPVVTATQMLESMIKSPRPTRAEATDVANAVLDGTDCVMLSGETAAGAYPELAVRTMARICVEAENTLDYGDVFKRIMQHSPVPMSPLESLASSAVKTANSAKATLILVLTRGGSSAKLVAKYRPGMPILSVCSDEAPARHSLIFRGLIPVLSAGSARASDAETTEEALEFAIHFAKEKGLCKNGDSVVALHKLDNAS----IIKILTI 496
622 0.000e+00UniRef50_A0A2N1JEG5 Multifunctional fusion protein n=1 Tax=Malassezia vespertilionis TaxID=2020962 RepID=A0A2N1JEG5_9BASI  ali  55  641......................IICTIGPKTNTIPMLHKLRNTGMNIG----THGTHEYFQSVIDNSHQVEREAPGRPLAFALDTKGPEMRTGVMIDEKDVNVEEGHEFIVTTDEKYADKCSAEHLYIDYKKLPQMVKPDRIIYIDDGILALRVLSI-EGTDVHVVSINNGTLSSRKGVNLPLTEVDLPAVSDKDRRDLEFAREHQLDMVFASFIRSKNDIITIREILGEKGAHIRIIAKIENHQGLQNFDEILDAADGIMVARGDLGIEIPAPQVFLAQKMIISRCNIVGKPVICATQMLESMTVNNRPTRAEVSDVANAVVDGADCVMLSGETAKGMYPTEAVKMMAETTYIAEQTLAYQALFNEMRALTRVPTNTNETIALVAVSASLEQKAGAILLMSTSGNTARLVSKYKPQCPILMVTRNAYTARSCHLYRGTYPFHYPPDHNSKWQEDVDNRVKFGLSEALKLHIIRKDDVVIAIQGWRGGKGHTNSLRILTV 1116
623 0.000e+00UniRef50_K6P002 Pyruvate kinase n=4 Tax=Firmicutes TaxID=1239 RepID=K6P002_9FIRM  ali  38  4..................RRTKIVCTLGPSTDDPWVLRRLLEAGLDVARINLSHGTADDHRRRVEMLRQVAAELGRRDVGILFDTRGPEVRVGPLPGGA-LELAGGQRVALVAAEGGRAPAGCPVIPVSYSRVATSVGPGDRILLDDGNLVLTVEET-DGVYVYCRVDAGGRLLQGKKATLPAESLDLPYLNEADRADVRLGIELGIDFIAASFVRSAADVHALRRVIEEAGGDQWVIAKIENRLGVERLDEILASADGIMVARGDLGVELPVEDIPLLQKQIIQAANRAGKPVITATQMLESMVHHPRPTRAESTDVANAILDGTDAVMLSAETAAGQYPVEAVEIMARIARRTEAALDYAQRLA--RTGREEHRTVTDAVSYASCTAAEDLGAAAILTATQSGYTSRMISRHRPRQPIVAVTPSQRVARKLSLVWGVRALVTAPQH------DVDGLMEEAMRGAVEGGFVRPGDLVVITAGVPVGPGTTNMLQVHTV 489
624 0.000e+00UniRef50_A0A2A2CY79 Pyruvate kinase n=113 Tax=root TaxID=1 RepID=A0A2A2CY79_9ACTN  ali  38  1.................MRRSKIVCTLGPAVDSFEQLKTLIEAGMNVARFNMSHGTHKEHEERYDRLRKAVDE-TGRAVGVLADLQGPKIRLETFADG-PVELVRGDEFTITTEDV---PGDKTICGTTYKGLPGDVSKGDQILINDGNVELRVTEV-EGPRVRTIVIEGGVISDHKGINLPGAAVNVPALSEKDIEDLKFALAMGCDMVALSFVRDAKDVLDVHRVMDEVGRRVPVIAKVEKPQAVANMQDVVMAFDGVMVARGDLAVEYPLEKVPMVQKRLIELCRRNAKPVIVATQMMESMITNSRPTRAEASDVANAILDGADAVMLSAESSVGAYPIETVKTMSRIVEAAEEELLSKGLQPLVP--GKKPRTQGGSVARAACEIADFLGGKALVAFTKSGDTARRLSRYRTAQPILAFTTDASTRNQLALSWGVETYVVP------HVDNTDAMVDLVDAELLKLKRYSEGDTMIITAGSPPGPGTTNMVRVH.. 468
625 0.000e+00UniRef50_Q9RR62 Pyruvate kinase n=23 Tax=Bacteria TaxID=2 RepID=Q9RR62_DEIRA  ali  36  6..................RATKIVATVGPASRSTEVLGRMIDVGLNVVRLNFSHGDLEDHRQTVQMVRDLAVS-KGVTIGILQDLQGPKIRVGRFAEG-SVTLNPGQKFVITMDEV---EGNAERVGSTYKGLAGDVTPGMTLLLDDGNMSLRVDHVR-GNDIQTTVLIGGTLKNNKGINVPEADLTVPALSEKDVQDMEFGASLGVDWVALSFVRSRDDLLLARHYLARFGSRAKLMAKIEKPQAVDRFADILKEVDGVMVARGDLGVEMRPEQVPTIQKRIIRMCREAGKPVITATQMLESMINLPRPTRAEASDVANAIYDGTDAVMLSAESAAGQYPVESVAMMDRIAREAEASELYQLMQRQVVMDTEQAQD---AIALAACNIGAKLEAPAIVTFTSTGGAATRISKNRPPLAIVALTPNEITRNQLALSWGVYPMLSED------PEDTDDMVRIANDELKKSGLADVGDRYVITAGVPFGVGTTNMLRVEK. 472
626 0.000e+00UniRef50_D3V1T3 Pyruvate kinase n=159 Tax=Bacteria TaxID=2 RepID=D3V1T3_XENBS  ali  43  1.................MKKTKIVCTIGPKTESETKLTELLNAGMNVMRLNFSHGDYEEHGQRIKNLRAVTAK-TGKKAAILLDTKGPEIRTIKLEGGNDVSLTAGQTFTFTTDKSVV--GNQECVAVTYAGLPADLKPGNTILVDDGLIAMTVKNITE-TEVICEVLNNGDLGENKGVNLPNVAINLPALAEKDKQDLIFGCEQGVDFVAASFIRKRSDVLEIRDHLKAHGGHIQIISKIENQEGLNNFDEIMEASDGIMVARGDLGVEIPVEEVIFAQKMMIEKCNAARKVVITATQMLDSMIKNPRPTRAEAGDVANAILDGTDAVMLSGESAKGKYPIEAVSIMATICERTDRIMNSR-----IENIKTQKLRVTEAICRGAVEIAEKLEAPLIVVATYGGKSARSIRKYFPNAPILALTTNEITARQLLLVKGVSTQIVKEIAS------TDDFYRIGKEAALASGIANKGDAVVMISGALVPSGTTNTSSVHV. 468
627 0.000e+00UniRef50_R9PI85 Pyruvate kinase n=6 Tax=cellular organisms TaxID=131567 RepID=R9PI85_AGAAL  ali  44  1.................MKKTKIVCTIGPKTESVEMLTKLVESGMNVMRLNFSHGDFAEHGTRINNLREVV-KNTGKSAAVLLDTKGPEIRTIKLAGGEDVSLVAGQEFTFTTDQTVI--GDATRVAVTYPGFAADLKVGNIILVDDGLIEMEVIAVSDD-EVKCTVLNNGDLGENKGVNLPGVIVQLPALSAKDKGDLIFGCEQGVDFIAASFIRKKEDVLEIRQLLKENGGKIQIISKIENQEGVDNFDEILEVSDGIMVARGDLGVEIPVEEVIFAQKMMIEKCNRARKLVITATQMLDSMIKNPRPTRAEAGDVANAILDGTDAVMLSGESAKGKYPVEAVSIMATICGRTDAVMPSNLD----PARDSGKLRITEAVCKGAVETSEKLSAPLIVVATEGGKSAKSVRKYFPQANILAITTNTKTAAQLCLTKGVIPHVVESI------ESTDSFYALGKDLAMESGLANKGDIVVMVSGALVPSGTTNTSSVHV. 469
628 0.000e+00UniRef50_A0A158QYJ6 Pyruvate kinase n=1 Tax=Nippostrongylus brasiliensis TaxID=27835 RepID=A0A158QYJ6_NIPBR  ali  46  481.NRLEHLCRLDIRDPPHHRKTGIICTIGPSCRSVEMLKQMITCGMNIARLNFSHGTHEYHAGTIKNVRQAVEQMKDIQVGIALDTKGPEIRTGLLTGGPSIELIKGKQITLTTDDKHKEACTAELLYLDYKNIVKVVSKNSRVYVDDGLISLVVNEVNND-SVLCTVENGGMLGSKKGVNLPGTLVDLPAVSEKDIQDLKFGVEQGVDMIFASFIRNGEGVRAMRKVLGEKGKHIKIIAKIENQEGMEKADDIIHEADGVMVARGDLGIEIPTEKVFLAQK----------------------------------------VLDGADCVMLSGETAKGDYPLEAVKTMHFICRVSEDYKQQKRHRPSLQDAVPNSGSQSECMCLSANEFAQCQND---------------------------------------FYRSVFPVFYNKPKNGDFQGDIDHKVNHAIEFGKQQGIINRGDYLVVVQGWKDG............ 895
629 0.000e+00UniRef50_C4K4N6 Pyruvate kinase n=15 Tax=Bacteria TaxID=2 RepID=C4K4N6_HAMD5  ali  43  1.................MKKTKIVCTIGPSSESEEMLVQLLNAGMNVMRLNFSHGDHNEHLQRIKNLRAVIKK-TNQKAAILLDTKGPEIRTKELKGGKEVSLSIGQTFTFTTDQNII--GDAHTVAVTYPGFANDLKAGDTVLVDDGLLAMEVIETQKN-AVICKVQNNGDLGENKGVNLPGISIKLNALTEKDKEDLIFGCQHSVDFVAASFVRKASDVLEIREFLNKKGEGIQIISKIENEEGLNNFDEILAVSDGIMVARGDLGVEIPVEEVIFAQKMMIEKCNRARKVVITATQMLDSMIKNPRPTRAEAGDVANAIVDGTDAVMLSGESAKGKYPIESVKIMASICKRTDLVMQSRIDF----LNENQEIRITEAICRSAVETAEKLNAHLIIVATSGGKSAKSVRKYFPHAMIMALTTNEVTERQLILTKGVFPFLVKKI------DSTDDFYHIGKKKALEQKLACKGDVVIMVSGALVPSGTTNTVSVQV. 469
630 0.000e+00UniRef50_C8P846 Pyruvate kinase n=45 Tax=Terrabacteria group TaxID=1783272 RepID=C8P846_9LACO  ali  39  1.................MKKTKIVSTLGPASTDVDTIVKLIQAGANVFRFNFSHGDHPEHLGRMQNVKKA-EEITGKHVGIMLDTKGAEIRT-TVQKEGKIEYNIGDEVRISMDDSI--EGTHDKIAVTYPGLYDDTHVGGHVLFDDGLIDMQIEEKDDNRELVCKVLNHGVLGSRKGVNAPGVSINLPGITEKDSSDIRFGLDNKINFISASFVRKPQDVQDIRELLKEKNEDVQIFPKIESQEGIDNFESIIEVSDGLMVPRGDMGVEIPAENVPIVQKHMIKRCNELGKPVITATQMLDSMQENPRPTRAEVSDVANAVFDGTDATMLSGESANGDYPVESVAMMNAIDIKAENHLWEFG----TETFDWDKSDVTETIGSAVSNAAKDLDIHTIVAYTASGYTAKMISKYRPNADIVALTPNERVERGLMINWGVQPYVVDEMT------NTDTMFDLAAKKAVELGFAKKGDKIIIVAGVPLGPGATNMMRVKTI 472
631 0.000e+00UniRef50_A0A0F7W199 Pyruvate kinase n=18 Tax=Actinobacteria TaxID=201174 RepID=A0A0F7W199_9ACTN  ali  35  1.................MRRAKIVCTLGPATDSYDQIKALVDAGMDVARFNLSHGTHAEHEQRYRRVREAADE-TGRSIGILADLQGPKIRLGRFAEG-PVLLERGDTFTITVEE--GTEGDRHLCGTTYAGLADDVRPGERILVDDGKVCLEVTGV-DGPRVRTTVTEPGVVSDHKGLNLPGVAVSVPALSKKDEEDLRWALHTGFDVIALSFVRTAHDIQDVHRIMDEEGRRLPVIAKIEKPQAVDHLEDIVAAFDGIMVARGDLGVEMPLEQVPIVQKRAVKLAKRNAKPVIVATQMLDSMIDNSRPTRAEASDVANAVIDGTDAVMLSGETSVGKYPIDTVRTMARIVEAAEEDILARGLPPLTERN--KPRTQGGAVARAAAEMGDFLGARFLVAFTQSGDTARRLSRYRSPIPLLAFTPAPATRSQLSLTWGVETYLGP------HVDSTDAMVDQVDELLTENGRCREGDLVVITAGSPPGSGTTNLVRVHRI 471
632 0.000e+00UniRef50_T1EM15 Pyruvate kinase n=3 Tax=Bilateria TaxID=33213 RepID=T1EM15_HELRO  ali  45  25.TQLESLSSLDIDSPYPYRLTGIVCTIGPASQSVEVLEKMFEAGCSVARMNFSHGSKEYHTQTLENVRAAASRFW-LPICIALDTKGPEIRTGIL----------------------KEACDEKTIFVDYKNIVNVMSVGKSILINDGAISLIVRDKGP-FYLKCEVEYGGLLSNSRGVNLPGTDVDLPAVSEKDVKDILFGVDNGVDVIFASFIRSGDAVRSIRQILGDKGKKIKIFSKIENREGVKRFNEILEASDGIMIARGDLGVEIPLEKVFLVQKMITARTLRTGKPIICATQMLESMIENPRPTRAETLDVANAVMDSVDCIMLSAETAKGKWPILCIEIQSKIAKEAECALYHRQLFEELRMLTPKPTDIPRTTAVSAVEASIECMASAIIVLTVSGRSAAMISSYRPRCPIMAVTRDETTSRQLRLFRGVIPIWYKAPKASPFEKDIDNRFQYALKLGEQKGLININNFVVVVHGSKPGSSSTDSVRVIQ. 499
633 0.000e+00UniRef50_UPI0009E05945 pyruvate kinase n=1 Tax=Acidobacteriaceae bacterium URHE0068 TaxID=1380348 RepID=UPI0009E05945  ali  35  7..........SLSDSATQRRAKIVATLGPASNTEPVFRDLVRAGIDVVRLNFSHGTHEEKLGLIQMIRKISRE-ERRPLCILGDLQGPKIRTSKLKDRQPVMLQAGKRITITPREV---PGTASLVGTTFKTLAENVEQGSRILLSDGLIELRVHEV-DGNDVVCEIINGGMLGENKGINLPGIPVRVPSLTEKDDADLEFALKNGVDAIAVSFVRTAEDIRLVRNRVSAYGSETWIIAKLEKPQGIEHLDSILQVADGIMVARGDLGVEVPPEKVPAIQKHIIRRASEYRKPVITATQMLESMIENPRPTRAEASDVANAVYDGTDAVMLSGESAVGKYPVEAVSMMSRIVQEAERTIKEQASY---TRTHESHLSIAETICEATAHAAEDLDLRGIALFTESGATARQLSKYHPQAPIFGLSPVDVTINRLNLLWGTVPIRCPK------VNSTEAMVDLAESLLESGGFVRPREVIAIVAGTRTKSGSTNFLRLHV. 481
634 0.000e+00UniRef50_S6A906 Pyruvate kinase n=2 Tax=Treponema pedis TaxID=409322 RepID=S6A906_9SPIO  ali  43  1.................MKKTKIVCTIGPASESERVLKEMFKAGLNVCRLNFSHGTHEEHKIKIDRIKKIREDL-GLPIAIMLDTKGPEIRLGNF--EKPAEIVQGQEFIITSREV---TGTNQICSISYKNLTKDIKLKSRILINDGMLELQVIDILNDTDIECVAVNSGTLTSKKGVNIPGLRVNIPYMSEKDIADIEFAIENDLDFIAASFIQNADDVMQIKNILNKHNSTIAVIAKIENQEGLDNIDSILEVADGIMVARGDLGVEIPPEKIPHEQKKLIRKANLAGKLVITATQMLESMTHNLRPTRAEVTDVANAILDGTSAVMLSGETAAGEYPVETVAMMNSIAVTTEATLDYEKLF--LENASLHETTVTNALARATCSTALSLGANVIITASASGITPRALSKFKPKIPIIAITPSVHAMRKLSLEWDVYPVLSPIIHS------TDNMFNICSQIAKEAGYVKTGDLAILTAGIPIGSGSTNLLKVQTI 470
635 0.000e+00UniRef50_C1F875 Pyruvate kinase n=25 Tax=root TaxID=1 RepID=C1F875_ACIC5  ali  36  15..................RRAKIVGTLGPASSHADVFRELVRAGLDVARLNFSHGTHPEKLKLIEMVRTVAAE-EKKTICILADLQGPKIRTGRLQDRIPVQLKAGQTLTITPKDI---AGTATVIATTFPTLAENLTEGDRILLSDGLIELRVKSIQ-GEDVECTVMNGGTLGEHKGINLPGIPVKVPSLTEKDDIDLVFAVQNNVDAIALSFVRTAEDVKLVKDRIAALGSSTWVIAKLEKPQAIDNLEEILEAADGIMVARGDLGVEVPPEKVPAIQKHMIRRARAWRKPVITATQMLESMIENPRPTRAEASDVANAVYDGTDAVMLSAETAAGKYPIEAVHMMARIASETESNLEHSA---QEARPPHQRLSIPETICESMAHACEDLDVAAIAVFTETGTTARQLSKYRPKPPIYALSSVPEVINRMAMLWGVKPILCEKAYT------TEDMVDTAERLMQEGGYAKKQDILGIVAGTRTRSGSTNFLRLHII 482
636 0.000e+00UniRef50_P73534 Pyruvate kinase 2 n=373 Tax=cellular organisms TaxID=131567 RepID=KPYK2_SYNY3  ali  38  1...........MQTSPLPRRTKIVATIGPATQSKEVLRQLIQAGATTFRLNFSHGDHAYHQQSIRLIRQIAFEL-NQPVGILQDLQGPKIRVGKFLNDASVQLKNGDPYTLTSRPV---ECTETISSISYEYLADEVPSGARILLDDGKLEMLVEEVDTARDLHCRVIVGGTLSSNKGVNFPGVCLSVKAMTDKDKEDLMFGLDQGVDWVALSFVRNPQDIDEIKGLIAAAGKSVPVIAKIEKHEAIKDMQAVLEKCDGVMVARGDLGVELPAEDVPILQKKLIATANRLGIPVITATQMLDSMVNSPRPTRAEVSDVANAILDGTDAVMLSNETAIGKFPVEAVAIMAKIAERIE------QEDINPSQAEASRTSIPNAISSAVSQIAETLNAAAIMSLTKTGSTARHVSKFRPKTPILAVTPHVDVSRQLQLVWGVKPLLVLDLPS------TSQTFQAAINVAQENHFLRDGDLVVMTAGTLQGAGSTDLIKVEVV 476
637 0.000e+00UniRef50_A9WHK0 Pyruvate kinase n=42 Tax=Bacteria TaxID=2 RepID=A9WHK0_CHLAA  ali  40  1.................MRRTKIVATLGPATSTPERIAGLIRAGMNVARLNFSHGTHAEHAARIAMVRRAAAE-AGRHVAILQDLQGPKIRTGPLENGQPVELVAGQRFVITTEPIV---GDAHRVSTTYRALPLDVRPRDRILLSDGLIELVVTG-HTDTEVETEVVHGGRLREHQGINLPGVRVSAPAATEKDLADLAFGLEQGVDYVALSFVRRASDVREVKEFIRRAGKQTPVIAKIERPEALDVLPEILAEADGIMVARGDLGVEMPPERVPIVQKQIIAAANQALLPVITATQMLESMIHNPRPTRAEASDVANAIIDGTDAVMLSGETAAGAYPIEAVQMMALIADAVEASYTGGQHSTTPRWSIAPAQSTPRAIAAAACTIANSLPVRFIVVLTQSGASARLVSHYRPEVPILAFCPSEETARRTSLYWGVTPIXXXXXXXXXXXXXXXXXXXX------XTGMVRKGDLIVLSGGHPVYRGPTNFLKVITI 473
638 0.000e+00UniRef50_A0A1G1RPC0 Pyruvate kinase (Fragment) n=5 Tax=cellular organisms TaxID=131567 RepID=A0A1G1RPC0_9BACL  ali  46  1.................MRKTKIVCTIGPVSESLPMLKKLMETGMNVARLNFSHGDFDEHGNRIHTLRQAMQE-TGKTIAILLDTKGPEIRTGEL-KESPIELEQGKTLILTTE---IIAGDANKISITYKDLPKDVHVGSTILLDDGLIGLTVEDVT-DTDIICKIVNGGTIKSRRGVNVPGVSISLPGITDKDKQDILFGIEQDVDFIAASFVRKASDVMEIRELLEQNNSHIQIISKIENQEGVDNLDSILEVSDGLMVARGDLGVEIPAEEVPLVQKRMIKKCNLAGKPIITATQMLDSMQRNPRPTRAEASDVANAIFDGTDAIMLSGETAAGKYPVESVETMVKIAVRAESALEHNEIF--LWQSHSQQTSVTEAISQSVANSAIDLNAKAIVTPTESGYTARMVSKYRPKAPIIAVTPHEHVMRRMSLIWGVTS........................................................... 417
639 0.000e+00UniRef50_M7NL19 Pyruvate kinase n=3 Tax=Fungi TaxID=4751 RepID=M7NL19_PNEMU  ali  56  11.......SSLDINS-IKLRLSGIISTIGPSTNSVEMINKLRCAGVTIIRMNFSHGSYEYHSSVLKNAREAVKVLPGRPLAIALDTKGPEIRTGSTIDGKEYHVTMGHQLIVSTNPQYAEKCNDQILYVDYSRICCVVREGSIIYIDDGTLSLCVLEVVNSQTLKVVCLNEGIISSHKGVNLPGTDVDLPTLSEKDVMDLRFGVENEVDIIFASFIRSKNDIITIRQVLGEAANKIKIIAKIENKQGIDNFDGILEEADGIMVARGDLGIEIPQTQVFIAQKMMISKCSIAGKPSICATQMLEHMIKNPRPTRAEITDICTAILDGADCCMLSGETAKGLYPIESVTMMRDSILIAESVIRYETFFNELRQLIPKDVSVTEAICCAAVEAQYRNNAKAIILLSSSGLTARLCSKYRPRVPIIMVTRSESVARFSNLYRGVYPLLYKYQTIEEWQESVNFRINWAIKQAIDLEIVQSGDNLVIIQGYRDGFGHSNTVKLHKI 508
640 0.000e+00UniRef50_A0A1W9PQ96 Pyruvate kinase n=1 Tax=Desulfococcus sp. 4484_241 TaxID=1968522 RepID=A0A1W9PQ96_9DELT  ali  39  4...............IRKRRTKIVCTIGPACSSEEKIVEMIRAGMDVARLNFSHGDYETHGKAIDLIRRIAAA-EDREVGILQDLGGPKIRLGVLPHGER-SLEAGKTVRLFAGE----KSDDDRLPVNYPYLLEDVGCGDRIILADGLVELAVSEKTRD-ELVCKVLVGGKIDSHKGVNLPASTLRVPAFTEKDKKDLAFGLEKGVDFVALSFVRHEKDVAPVTEMLGDRIDRPLCIAKIEKPQALERFDAILKAVDGVMVARGDLGVETPLHEVPVIQKRIISMARDAAKPVITATQMLRSMISNPRPTRAETTDVANAILDGTDAIMLSEETAAGDYPVESVRFLDRIAVAAESYLFENT--RRMEKLSVHIPGTAAAISHAAVELAYDLDASAIVAYTSSGSTARLVCRFRPKSPILGFTTSLKILRRLSLSWGVTPVFVPPY------EDTDDMFAMARKWISEQGIADRGGRIVLTAGVPVGPGTTNMVKVV.. 472
641 0.000e+00UniRef50_A0A1W9WH71 Pyruvate kinase n=2 Tax=Desulfobacteraceae bacterium 4572_87 TaxID=1972443 RepID=A0A1W9WH71_9DELT  ali  38  5...................RTKIVCTIGPATHSRKVLKELILAGMNVARLNFSHGAHADHKKVADSVKSLSRSLK-RPVAIMLDLQGPKIRTG-LIKGGTLSVKAHDPFTITTRAIKGEPG---IISTTYRGITKDVQPGDKILMDDGLIELKVRNKNR-TDLFCEVVNGGIIGEHKGINLPGITTGIPAVTEKDKKDLDFALDMGIDFVAASFVRSARDIQILKRILKKKGANIPVIAKIEKPEALDKLDEILDASEGIMVARGDLGVELSPEKVPVAQKKMITLANEKRKLVITATQMLESMTEHPLPTRAEASDVANAIVDGTDAIMLSGETSVGKYPVKAVKMMARIARVTEKNFPAARHF------LRKTSNFSDTISETACMAAENLGLSAITPFSQSGFTARLISKFRPSVPIIALTPTEAVQRSLALSWGVKAILIPLM------DNSDVMIKAMEELLRKKRLVRKNDRIVIVAGFPLKKGKTNMMKLHVV 468
642 0.000e+00UniRef50_A0A2G6M1Z7 Pyruvate kinase n=4 Tax=Synergistetes TaxID=508458 RepID=A0A2G6M1Z7_9BACT  ali  41  5...................KVKIICTLGPASSDKETLVKMIQSGMTVARLNFSHGSHEEHSGRLALLRSLTDVY-GAPVPVMLDTKGPEIRTG-LVEGDLVQLTSGETFALRLKDDAL--GDSSGVWVNYGLLGEEVRVGQDIFVDDGTLHLRVCSITDDQ-VLCDVLVGGDLGNRKGINVPGADFSFSVMSEKDREDILWGVRHDVDFVAISFVRDRQDVLAVRKVIEDAGGDIKLIAKVETHQAVANIETIAKVVDGMMIARGDLGVEIPTEDVPLVQKRIIDICRSQGKPVIVATQMLDSMIRNPRPTRAEASDVANAVLDGADVVMLSGETAAGKYPVQSVQTMARIIVKAEAELRRWQ---RPFQVPSVPNSVPDAVSMAAVEIAEKTGAKAIISLTRSGITARMVSKYRPKCPVVATTPSDKTQRELSLSWGVVPLY------KSSDDDENRAVEGAVTSALQRGLVSEGDLVVITAGMPLDPGTTNMVRVHTI 472
643 0.000e+00UniRef50_A0A235ICM8 Pyruvate kinase n=16 Tax=Nostoc TaxID=1177 RepID=A0A235ICM8_9NOSO  ali  40  1.................MRRTKIICTVGPATSAPEKLQALVKAGMNVARLNFSHGAYEFHAQTAHYLRQISTELQ-KPIAIMQDLCGPKIRLGTLPPEG-LNLEAGTEVTFVLQEK---GESIDELPLPLPTLFAMVRPGEPILINDGRVKLIVTDRDADR-IRAQVKNGGLISTHKGVNLPQTPLPVSSITEKDLLDLRFGIQLGVDWVAASFVRSPQDLEPARRMIEAAGASIRLIAKIERSEAVENFDSILNVADAIMIARGDLGVEVPIHEVPLIQKDIIRRCNRAGKPVITATQMLESMISAPDPTRAEATDVANSILDGTDAVMLSGETAVGQYPVAAVQMMHNIAVRTEQALDEGSKHAW--CHEAGSLSVTESVAESVCRIAYETGSRAILCNTSSGSTARMVSKYRPTSPIIALTSDITAYRQLALSWGVEALLIPPVH------NAEEMFTNVVNTVVDMGLANKGDKVVITSGVPIGSGTTSLIKVHSI 470
644 0.000e+00UniRef50_R4GAH2 Pyruvate kinase n=4 Tax=Bilateria TaxID=33213 RepID=R4GAH2_ANOCA  ali  51  21.TFLEHMCRLDIDSPPTARNTGIICTIGPASRSIEMLREMIKSGMNVARLNFSHGTHEYHAGTIKNVREATESFSYRPVAIALDTKGPEIRTGLIKGSAEVELKKGATLKLTLDNAFMENCDENVLWVDYKNITKVVEIGSKIYVDDGLISLQVKEKGAD-FLITEIENGGMLGSKKGINLPGAAVDLPAVSEKDIQDLQFGVEQGVDMVFASFIRKAADVHAVRKVLGEKGKNIKIISKIENHEGVRRFDEVMEASDGIMVARGDLGIEIPTEKVFLAQKMMIGRCNRAGKPIICATQMLESMIKKPRPTRAEGSDVANAVLDGADCIMLSGETAKGDYPLEAVRMQHLIAREAEAAIYHRQLFEELFRLTVNNRDPLDAIAVGAVEASFKCLAAAVIVLTESG---RLLAKQR..................................................................................... 438
645 0.000e+00UniRef50_A0A209DJ41 Pyruvate kinase n=6 Tax=Paenibacillaceae TaxID=186822 RepID=A0A209DJ41_9BACL  ali  39  2...................KTKIVCTMGPACDSVEMLKEMINSGMTVARLNMAHGEPADHSERIRKVRQAASEL-NTFVPIMMDIKGPEVRIGKFQ-EEYVQLEAGSELTLTTEPDVL--GTAERIGVNYPKLNEDLKAGDRILIDDGLIALDVLNV-EGTEIYCKILNGGRLKPRKGVNLPGVKTSLPGVTERDVMHINYGLSENVEIIAASFVRKGDDIREIRRILAEKGAHVQIISKIENQEGMDNLDDIIEASDGIMVARGDLGVEVPVQDVPAAQKLMIDKCNLAGKPVIVATHMLESMQVNPRPTRSEVSDVANAVLQGADCVMLSGESAAGKYPLESVRTMAAVAAKAETMIDYDVQFNS--KRALHLNDITEVVSQSSVNASLVLDAAALIISTESGFTARMISKYRPKAPIIAVTQNEKTLPKMSLLYGVVPVKGQEVSS------TDEMFEVATQNALESGYIKSGETVVLCAGIPIGKGSTNVMKVQQV 471
646 0.000e+00UniRef50_A0A0J1FWC5 Pyruvate kinase n=9 Tax=Firmicutes TaxID=1239 RepID=A0A0J1FWC5_9FIRM  ali  39  1.................MRRTKIVCTIGPASESRENVQALLAAGMDVARLNFSHGTHEEHGRRIAVLKEEAAKI-GKHLGILLDTKGPEIRTGMVPNEG-IRLENGMSFTLDTDLSL---GNQERVGITHKTLWQSVNPGTHVLIDDGQLDLEV-STVEQGIIRTVVRNGGILKSQKGVNVPGIHVDLPAVTEKDIDDIRFGVSQGIDFIAASFTQKAVDILDVRRIVEDMGAEVHIIAKIESQEGIANLDSILEVADGLMVARGDLGVEIPVEEVPINQKEMISKCNFMGKPVIVATQMLDSMIRQPRPTRAEASDVANAIWDGTDAIMLSGETAAGQFPIQAVQMMDKIARRTERT------FLESQANRHPQLNVAEAISYATYNIAKDLDAAAILTPTHSGLTAKMISKYRPKALIVAAAPLATTARKLSLQWGVQPIVVPESSG------TDEMLSVAVNSALTMNYISSGDVVVITAGVPIGVGSTNMIKVQII 466
647 0.000e+00UniRef50_P77983 Pyruvate kinase I n=1324 Tax=root TaxID=1 RepID=KPYK1_SALTY  ali  43  1.................MKKTKIVCTIGPKTESEEMLSKMLDAGMNVMRLNFSHGDYAEHGQRIQNLRNVMSK-TGKKAAILLDTKGPEIRTIKLEGGNDVSLKAGQTFTFTTDKSVV--GNNEIVAVTYEGFTSDLSVGNTVLVDDGLIGMEVTAI-EGNKVICKVLNNGDLGENKGVNLPGVSIALPALAEKDKQDLIFGCEQGVDFVAASFIRKRSDVVEIREHLKAHGGNIQIISKIENQEGLNNFDEILEASDGIMVARGDLGVEIPVEEVIFAQKMMIEKCIRARKVVITATQMLDSMIKNPRPTRAEAGDVANAILDGTDAVMLSGESAKGKYPLEAVSIMATICERTDRVMNSRLDY----NNDSRKLRITEAVCRGAVETAEKLEAPLIVVATQGGKSARAVRKYFPDATILALTTNEVTARQLVLSKGVVSQLVKEINS------TDDFYRLGKDVALQSGLAQKGDVVVMVSGALVPSGTTNTASVHV. 469
648 0.000e+00UniRef50_C9MVQ1 Pyruvate kinase n=26 Tax=Bacteria TaxID=2 RepID=C9MVQ1_9FUSO  ali  42  2................KIKMTKVVCTIGPKTESIEMLTKLVESGMNVMRLNFSHGDFEEHGARIKNIREVMKK-TGREIGILLDTKGPEIRTGKLEGGKDVLLETGKKVTITTD--YSFVGNAEKFAVSYPGIVDDLYEGTTVLLDDGLVGLKVESVDKAGEVHCVITNTGELGETKGVNLPDVSVGLPALAEKDIADLKFGCEQGVDFVAASFIRKASDVAEVRKVLDDNGKNIQIISKIESQEGVDNFDEILELSDAIMVARGDLGVEVPAEEVPFMQKMMIRKCNRAGKSVITATQMLDSMIRNPRPTRAEAGDVANAILDGTDAVMLSGESAKGKYPVEAVKMMATISKRT----DEFKKFKTIETPDGSEISVTEAISSGAVSTSHALDVKLIVCWTKTGRAPRMIRKYGPTVPIIALTDNEQTARQLALVRGVRAYVAKG------LDKTDDFFAKAREIAANHEEANKGDLVVMVTGI-SKEGTTNTFRVERV 473
649 0.000e+00UniRef50_C9KNA5 Pyruvate kinase n=8 Tax=Selenomonadaceae TaxID=1843491 RepID=C9KNA5_9FIRM  ali  40  2.................LKKTKIICTQGPATERPGVVDALIANGMNCARFNFSHGDHAEHLNRINMVREAAKK-AGKVISLILDTKGPEMRLGEFKDGK-VMLEKGNKFTLTYEDI---PGDETHVSVNHKGLYTEVKPGDTLLLSDGLVALKVDEIR-GKDIITTIQNSGKMSTKKRVAAPGVSLGLPPISEQDAKDIVFGCEQDMDFVAASFIQRPEDVLAIRKLIEEHNGHMEILPKIENLEGVKNFDAILEVSDGIMVARGDLGVEVPAEDVPLIQKEIIRKCNKAGKPVIVATQMLDSMERNPRPTRAEVSDVGNAILDGTDAIMLSGETASGDYPIEAVSTMNRIAMRIEESLEYKNLFVE--RGFEHSQSRTRAVAHATVQMAYELDVPAIITPTDSGYTTKIVSRYRPKAAIIAYTPHEKVVRQLNLRWGVYPIL------GTQWKDVDEMIANAVSAAVKDGFVKRGDTTIITSGIKLQSKTTNMIRVYKI 475
650 0.000e+00UniRef50_A0A2J6XB37 Pyruvate kinase n=4 Tax=Thermodesulfobium TaxID=227388 RepID=A0A2J6XB37_9FIRM  ali  43  2.................IRKTKIICTLGPSTDDPEILYNFVKNGMDVARLNFSHGDYEDHFRRIQMVREASKELK-REVALMLDTKGPEIRVGKFKSG-SVQLKKGQKFILTAEEI---EGNEEIVSVTYPDLIKKIKRGNVIVLSDGLISLQVEDT-DDKNIYTTVMNNGILKDHKRVAVPGVFLDMQFLSEKDINDIKFGIENEMDFIAASFVQNASNILEIRRVLEENNSNMDIIAKIENRFGIDNIDEILKVADGIMVARGDMGIDIPNEDVPLIQKELIKKANKIGKPVITATQMLESMINNPHPTRAEASDVANAILDGTDAVMLSGETAAGNYPLEAMEMMARIALKTEMSLDYKVIF---LSKGLNQKTTTDAISHATVQISHELDAAAIVSITQSGYTAKMVSKYRPNAFIIGVSPDIRMVRKMKLIWGVYPIKCER------TNNTEEMVLEAISKSTASNLIKEGDLVVITAGVPLGAGTTNMIRVHLV 470
651 0.000e+00UniRef50_A0A2G7H092 Pyruvate kinase n=24 Tax=Deinococci TaxID=188787 RepID=A0A2G7H092_9DEIO  ali  35  6..................RATKIVATVGPASRSPEVLSRMIDAGLNVVRMNFSHGDREDHRQTLQMVRELAAK-KGVTIGILQDLQGPKIRVGRFAEG-SVTLAPGDKFTITMDDV---EGDATRVGTTYKALIHDVTPGMALLLDDGNMALRVEGVR-GNDVLTTVVIGGVLKNNKGINVPEADLSVPALSEKDVQDMEFGAELGVDWVALSFVRSRDDLLLARHYMSRFGSRAKLMAKIEKPQAVDRFEDILKEVDGIMVARGDLGVEMRPEQVPTIQKRIIRMCREAGKPVITATQMLESMISLPRPTRAEASDVANAIYDGTDAVMLSAESAAGLYPVESVAMMDAIAREAEASEHYKMLQRQLVIDTELAQD---SIAYAACNIGEKLDSPAIVTFTSTGGAAARIAKNRPPLAILALTPNETTRNQLALSWGVVPVLSEDPR------NTDDMVRIANDELRRSGLAEVGDRYVITAGVPFGVGTTNMLRVER. 472
652 0.000e+00UniRef50_Q1Q4I4 Pyruvate kinase n=30 Tax=cellular organisms TaxID=131567 RepID=Q1Q4I4_KUEST  ali  37  2...............NNYRKTKIVCTIGPASNSPAMIEQLICAGMNVARLNFSHGELSQHKECISHIRAISEKLM-QPVAVLQDLSGPKIRIGMLSGDA-VTLKTNDTFTLTTRNIV---GNERVISINYSDLPMNVSIGDTLLLSDGEIEVEVIQK-DDRNIHCKVIVGGVLTSRKGINIPARSLPVSSLTEKDKKDLEFGIEQGVDYVAMSFVKTAEDITELRDLIQKKGKTIPIIAKIEKHEAVDNIEKIVNTADAIMVARGDLGVEIPLERVPSVQKMIIRLANRYGKPVITATQMLASMVNNYRPTRAEVTDVANAILDGSDAVMLSEESAIGRYPADAVLMLTKIAKQIEPDLTQSNTFEKF-RIPENRTTIPDAISIATCQVANELNMNTIITCTQSGSTARFISKYRPRQKILAVTPSVCTYRRLALVWGVIPILTESM------ENTDDMMKKGIEAAKQAGYIGENETIAITGGVPVGPGSTNLLRV... 471
653 0.000e+00UniRef50_UPI000181F54B Pyruvate kinase n=1 Tax=Toxoplasma gondii TaxID=5811 RepID=UPI000181F54B  ali  43  37...................RTRIVCTMGPACWNVDTLVKMIDAGMNVCRLNFSHGDHETHARTVQNIQEAMKQRPEARLAILLDTKGPEIRTGFLKDHKPITLQQGATLKIVTD--YNLIGDETTIACSYGALPQSVKPGNTILIADGSLSVKVVEVGSD-YVITQAQNTATIGERKNMNLPNVKVQLPVIGEKDKHDINFGIPMGCNFIAASFVQSADDVRYIRGLLGPRGRHIRIIPKIENVEGLVNFDEILAEADGIMIARGDLGMEIPPEKVFLAQKMMIAKCNVVGKPVITATQMLESMIKNPRPTRAEAADVANAVLDGTDCVMLSGETANGEFPVITVETMARICYEAETCVDYPALYRAMCLAVPPPISTQEAVARAAVETAECVNAAIILALTETGQTARLIAKYRPMQPILALSASESTIKHLQVIRGVTTMQVPSFQG------TDHVIRNAIVVAKERELVTEGESIVAVHGMKEEAGSSNLLKVLTV 510
654 0.000e+00UniRef50_A0A1C5NMF0 Pyruvate kinase n=13 Tax=Terrabacteria group TaxID=1783272 RepID=A0A1C5NMF0_9FIRM  ali  39  1.................MKKTKIVCTIGPSTDDENIMRELMKNGMDVARFNFSHSDHSVHKARFETVCKLREEL-GVNIATLLDTKGPEVRLKNFKDHKPVTIKDGDTFTLTTREV---EGDETICSITFPQLPKDVSVGTRILINDGNIELKALRV-DNTDIVCEVIHGGVVSDHKGINVPDVNLSMPYISDADMSDLEFGAKMGFDYIAASFVRTGADVIYLRKFTQSLGWNPRIIAKIENAQGVANIDEILDAADGIMVARGDMGVEIPFEQIPAIQKELIRKAYNAGKNVITATQMLESMITNARPTRAEITDVANAIYDGSSAIMLSGETAAGKYPVEAVKTMSLIAETTEKDIDYISRFK--KRADERNSSITDAISHATVTTAHDLNAVAILTVTKGGTTARTLSKFRPNCPIIALTTDETTYHQLSLSWGIRAGVIEEKT------NTDELIRHALERSVELGYLKKGDLVVITAGVPLGSGTTNLLKVER. 471
655 0.000e+00UniRef50_Q42806 Pyruvate kinase, cytosolic isozyme n=256 Tax=Eukaryota TaxID=2759 RepID=KPYC_SOYBN  ali  41  19................RVPKTKIVCTLGPASRSVEMTEKLLRAGMNVARFNFSHGTHDYHQETLNNLKTAMH-NTGILCAVMLDTKGPEIRTGFLKDGKPIQLKEGQEVTITTD--YDIKGDPEMISMSYKKLPVHLKPGNTILCSDGTITLTVLSCDPDGTVRCRCENTATLGERKNVNLPGVVVDLPTLTEKDKEDILWGVPNKIDMIALSFVRKGSDLVNVRKVLGPHAKNIQLMSKVENQEGVLNFDEILRETDAFMVARGDLGMEIPVEKIFLAQKMMIYKCNLVGKPVVTATQMLESMIKSPRPTRAEATDVANAVLDGTDCVMLSGESAAGAYPELAVKIMARICIEAESSLDYGAIFKEMIRSTPLPMSPLESLASSAVRTANKAKAKLIVVLTRGGSTAKLVAKYRPAVPILSVCSDETPARHSLIYRGLIPILGEGSAKATDAESTEVILEAALKSATERALCKPGDAVVALH----RIGAASVIKICIV 510
656 0.000e+00UniRef50_A0A097IU68 Pyruvate kinase n=17 Tax=Stramenopiles TaxID=33634 RepID=A0A097IU68_9PHAE  ali  45  24..................RKVKIICTLGPACWSVETLGALVDAGMNVARLNFSHGDHEGHAATLQRLREALSTRRGKHVAVLLDTKGPEIRTGFLANKKSAELTRGQELELTTD--YEFLGDNTKIACSYKSLPTSVQAGSKILVADGSLVLTVKECKE-TSVVCEVMNNCVLGERKNMNLPGAIVDLPTLTEKDIDDLQFGLVHQVDYIAASFVRKAEDIDTIRMVLGEEGAHIKIIAKIENQEGIRNYDEILLKTDAIMVARGDMGMEIPPEKVFLAQKYMIRRANIAGKPVVTATQMLESMIKNPRPTRAECTDVANAVLDGTDCVMLSGETANGDYPVDAVTMMSRTCCEAECALNYDNLYQAMRNTVMKEMEPAESVASSAVKTAIDLNAAMVVVLTETGTTARLLAKYRPDVPIXXXXXXXDAARQMNGYRNVQSQVIGSMIG------TDSIVFRAIDIGKQNGWVKPGDKVVCIHGMKEAAGSTNSMRVIV. 502
657 0.000e+00UniRef50_A0A2A2G6C7 Pyruvate kinase n=1 Tax=Aliifodinibius sp. WN023 TaxID=2032627 RepID=A0A2A2G6C7_9BACT  ali  37  6..................RRTKIVCTLGPSSNTEEKIDKLVRNGMNIARINFSHGTHEDNGKVIQNVRKVADRY-GVSLPILADLQGPKIRIGNMKEGGQ-EVEAGDYVTLTTEDI---EGTSETIPVDYKGLVDDAVEGNRLLIDDGLLELKVIKKNE-STLVAQVVVGGLLKSRKGLNLPDVDLSMASLTEKDIKDLEYALSQDVDYVAMSFVRSADDIQEVISRVRAEGSNAGIVAKIEKPEAITVIDDIIEESSGIMVARGDLGIEIASERVPMVQKNIIDKCRQAGKPVITATQMLDSMIENPRPTRAESSDVANAVLDGTDAVMLSGETAAGNYPVESVRTMDKICGLVEKNADHIYNSLEYRKPEWKEKQVIESLAYSCVMLAENVDAKVISTITHSGSTARRIAKFRPRVPIVAFTESDEVRQQLGMVWGVQPIKIDEIF------DTDKSVKLMEEHLKNHGLVNKDDRAIIATGMPIKKGRTNMIKVSTI 476
658 0.000e+00UniRef50_A0A1W9MK32 Pyruvate kinase n=1 Tax=Desulfobacteraceae bacterium IS3 TaxID=1934248 RepID=A0A1W9MK32_9DELT  ali  36  1.................MPKTKIICTIGPASESPEVIRELIRSGMNVARLNFSHGTHEEHKEKIAIIRAISEELA-KPVAILQDLCGPKIRVGNV-KEPGIRLEPGQTFVLTNE---TIEGTPERVSVSYSHLPSEVKAGDRILLADGMMELIV-DKTTLTEIYCKVITGGVLTSHKGINLPTGSIKAESITDKDKADLLFGLQHDVDYVALSFVRTSEDILNLKKIIKAENKKTPVIAKIEKHEALDHIEEIMAVSDGIMVARGDLGVEIPLATVPGIQKMLVRKANEAGRPVIIATQMLRSMVSAPRPTRAEATDVANAVLDGADAVMLSEETASGNFPAEAVRFMSRIAESAENDFPHDKYMQ-----LKHKRDISESVAYASCVLADHLGANAIVATTRSGSTAMQISRFRPRPQIIALSPEKSTIRKLALYWGCFPSFVSETR------NTDEHIENAAVSAIGTGNVSKGDVVVITAGHPVEEGTTNMIRV... 464
659 0.000e+00UniRef50_A0A1G1G6S6 Pyruvate kinase n=2 Tax=Bacteria TaxID=2 RepID=A0A1G1G6S6_9BACT  ali  42  3..................KRTKIIATIGPASSSPAIIARLIRAGMDAARLNFSHGERADHIKRISLIRSEAAKV-GKHIAIILDLQGPKLRVGAIKNDAAV-LKRNSTIMLLTRKIV---GTSEQVSVTYPRLTKDLKIGDTVLLDDGRLELRVVKKTS-HALSCKIIRGGVLKSHKGVNLPGVKLSLPSLSNKDKDDLRFGVKQGVDYIALSFVRTAMDIAQTRLFIHSLKTDIPIIAKIEKPEAILNLDEIICESDGIMVARGDLGVEMSPEKVPLLQKMIIEACHWAETPVITATQMLESMIENPQPTRAETSDVANAILDGTDCVMLSGETAVGNYPVQTVEFMTRIALQAETSVNPWPPDDDVAGLG-------ESVAHAACRAGEEQQAQAIVPFTQSGSTALLVSKHRPRMPIIAPTPFEQVARKVSLYWGVTPVILKAK------KTTDDMITSVEEIMLKKRLAKKHDLIIITAGVPIGAGSTNMMKIHRV 466
660 0.000e+00UniRef50_Q0W8N0 Pyruvate kinase n=15 Tax=root TaxID=1 RepID=Q0W8N0_METAR  ali  39  1.................MRKTKIVCTIGPACDSQDMLEKLAVAGMNVARLNMSHADHEHTVQTINNIRMVSEAI-GKPIGILMDLQGPKIRVGTLQQ--PANLKPGGTFTLTTRDV---PGDSQEVNVPFKELPQSVSTGQTLLLDDGLIELKVDAVTE-TDIRTKVVRGGELKSKKGINLPQSTIRIPSITEKDVRDLEFGIEHEVDMIAMSFVRKPQDVLDLRKKIEDNDSDIPIISKIEKHEAVKNIDGIIDVVDGVMVARGDLGIEIPMAEVPIVQKMIISKCIARGIPVITATQMLDSMIRNPIPTRAEATDVANAVFDGTDALMLSGETAFGEYPVKAVETMARIAKYTEESTYYKHAIAA--KAPKPSLSMTDAVAQSTTESARVLKAQAIITATQTGYSARKVSKYRPQLPILAVTNDPKVVNRLTLSWAVLPLLIGSPG------NLDELIQDSVDACLQKGYVKNGDLVVITAGVMTGPGGTNIMKIHVV 469
661 0.000e+00UniRef50_A0A0L6VDK8 Pyruvate kinase n=5 Tax=Fungi TaxID=4751 RepID=A0A0L6VDK8_9BASI  ali  62  10.SQLEWIAGLQIPPKSNLRKTAIIGTIGPKTNSPEMINKLRAEGLNIVRMNFSHGSYEYHQSVIDNARAAEAAQPGRPLAIALDTKGPEIRTGLMAGGVDIKIQAGHRMRMTVDPAYAEKCDDKIMYIDYTNLPKIISQDKPIFVDDGILSFKVLEKDNGMFIEVEAVNDGVLASKKGVNLPGTDVDLPALSQKDKDDLQFGVKNGVDIIFASFIRRAQDVRDIRDTLGPHGQNIKIICKIENLQGCANFDEILVETDGIMVARGDLGIEIPASQVFMAQKMMIAKCNLAGKPCICATQMLESMTYNPRPTRAEVSDVANAVLDGADCVMLSGETAKGSYPELAVAMMAETCFLAESSICYPPLFNELRMLQPKPTSTTETVAMAAVAAALEQNAGAIIVMS---------------------TSNAQTARQIHLHRGCYPFFFDCPRPTNWQADVDNRIKFGLARALELGIVKQGDTVVAIQGWRSGSTHTNTMRVVTV 498
662 0.000e+00UniRef50_D7CP24 Pyruvate kinase n=144 Tax=Bacteria TaxID=2 RepID=D7CP24_SYNLT  ali  42  1.................MRKTKIICTLGPSTDDYERLRALITNGMNVARLNFSHGTXXX-XXXXXXXXXXXXXXXXXXVGLMLDTKGPEIRTGPLKEGK-IELRPGQKFVLTNRPV---EGNEDEVQISYHELPSQVKAGDCILIADGVIQLSVLE-ANDTDIVCQVVAGGVLGERKGINLPGVRTNLPFLSQKDIEDINFGIQQNMDFIAASFVRTADDVLDIRRILEEKGADIDIIAKIESQEGLDNLDDIIKVADGVMVARGDLGVEIPTEEVPLVQKVIIEKCRAQGKPVIIATQMLESMVNVPRPTRAEASDVANAIFEGADAIMLSAETAAGKYPVVAVETMARIARRTEMALPYENMLAA--RRFEGRRTVTDAISYATCATATDLGASAIVTATKSGHTARMVAKYRPRAPIVATTPSPEVVRKLTLVWGVYALTVPETHG------TDQMIETALDAAVRRGLISPGDLVVITAGTPGIPGTTNLLRVQVV 469
663 0.000e+00UniRef50_A0A2P6NVQ8 Pyruvate kinase n=1 Tax=Planoprotostelium fungivorum TaxID=1890364 RepID=A0A2P6NVQ8_9MYCE  ali  45  129MATLNRNLKLKVDAHKKYRMTQIVCTIGPKTKSPEVLDKMMSAGMNIMRLNFSHGSHEYHGEVIANLRKALSKRGGSRCAIMLDTKGPEIRTGKL-KDKTIKLTAGQTINVSTD--LTLIGDDSTIIVDYQDLCTSVKVGGHILIADGQISLTITSINAGKTVTCTVNNTSVLGENKNTHLPGAKVNLPAVSEKDIKDLKFGVEQKVDMIAASFIRSAYDVLEIRKILGEEGRNIKIISKIESTEGLENFDSILKVSDGIMVARGDLGVELPMEQIFVAQKMMVSKCNAAGKPVITATQMLESMIQNPRPTRAEATDVANAVLDGTDCVMLSGETASGDYPLEAITYMAGICKEAENAATHYPTLFEGFRTACEDLSTPEVVASYAVRASNDVGASLLVTLSETGATARLACKYRPRVPVICVTHHEHVANSLLLTRGAVPFLVSTQKDAA-----EFLIGLAMEKGKVMGLCKPGSLVVVISGTMFVPGGTNTLRVI.. 628
664 0.000e+00UniRef50_Q46289 Pyruvate kinase n=52 Tax=Clostridium TaxID=1485 RepID=KPYK_CLOPE  ali  41  1.................MQKTKMIFTIGPSSDSEEILREFIRIGMNAARLNFSHGDHASHKEKIELIKRLRKEEKSAT-AILLDIKGPKIRTYNFKNGEA-ELKNGDEFTFSCGDEIL--GDNTKCSISYKELYEDIKPGGSILVDDGLLEFKVKEVR-GTDIICEVIEGGTIKDHKGVNVPNVPIKLPAVTEKDRSDLIFGCEMEVDFVAASFIRKPEDVLEVREILDSHGKDIKIISKIESQEGVDNIKEIIKVTDGVMVARGDMGVEIPIENVPIIQKNIIKKCNQAGKIVITATQMLDSMIRNPRPTRAEASDVCNAIFDGTDAIMLSGESASGSFPIEAAMTMSRIAKKAEANLDYNYLLRRLKDPNPNPDAFADAISYSASKTASKFPTKAIVAATQTGSTAKILSKYKPSCPIIAITPYEKVRRSLALNFGIIS------KKCAYFNSTDEIIEEARKVAKEFEIAETGDNIMVAAGFPTSTGGTNMLKIEKI 474
665 0.000e+00UniRef50_A0A1X0P7Q1 Pyruvate kinase n=1 Tax=Trypanosoma theileri TaxID=67003 RepID=A0A1X0P7Q1_9TRYP  ali  49  1MSQLAHNIGLSIFDPPNYRANRIVCTIGPSTQSVEALKGLMKSGMSVARMNFSHGSHEYHQTTINNVRTAAAEL-GMHIGIALDTKGPEIRTGLFVGGEAI-LMTGDTVLVTTDPAFEKTGTKEKFYIDYPRLATTVRPGGSIYIDDGVLNLKVISKEDDCTLKCYVNNGHRLTDRKGCNLPGCEVDLPAVSAKDREDLKFGVEQGVDMIFASFIRTAEQVREVRATLGEQGKETLIISKIENHQGVQNIDAIIDASDGIMVARGDLGVEIPAEKVVVAQMTLISKCNVAGKPVICATQMLESMTTNPRPTRAEVSDVANAVFNGADCVMLSGETAKGHYPNEVVQYMARICVVAQSATNQYVMFNSIKSMQKLPMSPEEAVCSSAVNSVYEVEAKALLVLSNSGRSARLASKYRPNCPIICATTRMRTCRQLNITQSVESVFYDAERYGP-DDDKENRVQLGVEFAKKKGY............................ 470
666 0.000e+00UniRef50_A0A2N2KJW3 Pyruvate kinase n=3 Tax=Bacteria TaxID=2 RepID=A0A2N2KJW3_9DELT  ali  38  1.................MQKTKIVCTIGPASEKEEVLEAMILNGMNVARLNFSHGSHQDHLEKIILLRKLSASLQ-KPVAILLDLAGPKIRIGQMPDSG-VLLEPGHKFILTNRDV---EGSVDAVSLSHKNLPREVKPGDRLLLADGLMELFV-EATGESDIICKVVTGGTLTSHKGINLPTGTISTSALTEKDRADLLFGLENDVDFIALSFVKNAEDIMMIKDIIAANGKDTPVIAKIEKHEALNHIDAILKISDGIMVARGDLGVEIPLEDVPLIQKRLIYKANMCGKPVITATQMLRSMVTSPRPTRAEAADVANAVLDGTDAVMLSEETASGNYPAEAVMYLSRLATVAES----GYAFEKFLSMIPEK-DISESVAHASSVLASHLSARAIVAYTQSGRTARYISRFRPRQPIIALSPKENTVRRLALSWGCRPRLINDFQ------DTDDMIEKATQAACDAGEVSAGDLIVITVGHPLWSGTTNMLRVKRV 467
667 0.000e+00UniRef50_I1KMC2 Pyruvate kinase n=113 Tax=Viridiplantae TaxID=33090 RepID=I1KMC2_SOYBN  ali  41  12...................KTKIVCTLGPASRSVPMIEKLLRAGMNVARFNFSHGSHEYHQETLDNLR-AAMENTGILCAVMLDTKGPEIRTGFLKDSKPIQLKQGNEITISTD--YDLKGDEKTICMSYKKLPEDVRPGMVILCADGTISFTVLSCDKAGLVQCRCENSATLGERKNVNLPGVIVDLPTLTDKDKEDIAWGVPNKIDMIALSFVRKGSDLVEVRKVLGKHAKNIMLMSKVENQEGVANFDEILANSDAFMVARGDLGMEIPIEKIFLAQKVMIYKCNIQGKPVVTATQMLESMIKSPRPTRAEATDVANAVLDGTDCVMLSGETAAGAYPDLAVRTMAKICIEAESTLDYGDVFKRIMEHSPVPMSPLESLASSAVRTANSARAALILVLTRGGSTAKLVAKYRPGMPILSVCSDEAPARHSLIFRGLVPVLSAASARASHAETTEEAIEFAMQHAKSKGLCHNGDSVVALH----RVGTASVIKILTV 500
668 0.000e+00UniRef50_D3R1L7 Pyruvate kinase n=15 Tax=Clostridiales TaxID=186802 RepID=D3R1L7_MAGIU  ali  39  1.................MRKTKIICTLGPATDDENVLRELVRSGMNLARFNFSHGTHEEHFKRLQLLRRIVAE-EGATVATLLDTKGPEIRTGQFPEGK-VELKMGEKIVIRHDDV---PGNAHEFSVSYKDMHKDVKVGSPILIDDGSVELLVDSISPEGDISCTIQNGGFVSDYKSINLPDSFVNLPALTERDVSDLKFAVDNDMDFIAASFVRRPSDVAEIRQTLERFGRDIRIIAKIENREGVDKFEEILHVSDAIMVARGDLGVEIPAYEVPRVQKNMIRLCYRFGIPAITATQMLDSMIRNPRPTRAEVSDVANAIMDGTSAIMLSGETASGKYPVEALQMMSRIAEETERNYDYWDFFRHAGEKVRP--TVGNAISHSCCTTAMDLQAKAIVAMSISGRTARLISRFRPGCPIIATAASEKVSRQLQLSWGVIPYHVKPVNT------TDAIFQKGVDIAVNSGLVKTGDVVVITCGTPVGSGTTNTLKVQNI 472
669 0.000e+00UniRef50_U2PZD1 Pyruvate kinase n=105 Tax=Firmicutes TaxID=1239 RepID=U2PZD1_9CLOT  ali  42  1.................MRKTKIICTIGPASDSDEILSKIIEAGMNASRHNFSHGDHAEHATRINKVKELAKKY-NREIAVLLDTKGPEIRTGKFEPSK-VELTVGTDFTIYPGGDVV--GDTTKCSVTYTGLAKDVKAGDTILIDDGLVGLEVKSVEEGK-VNCVVKNTGMVGTHKGVNVPGVAIKLPAMTEKDESDLKFGCEIGVNMVAASFIRKAEDVIAIRKILEENGGHIDIYSKIENQEGVDNIDEIIAVSDGIMVARGDLGVEIPIEKVPAVQKMIIDKCNAACKPVITATQMLDSMIRNPRPTRAEVSDVANAILDGTDAIMLSGESANGSWPVESVETMAKIAKETETQLSYELAVSSAKRHIPA---IGGVISRAACNAAYELKASSIISSTQSGATAKRISQCRPDCAIIAVTPDEKVAKKLALSWGVYPIVAER------VNSTDEMMEKTVDIAKTTKYVKSGDTVVIVAGVPVKVGATNMMKISIV 471
670 0.000e+00UniRef50_A0A2E6N654 Pyruvate kinase n=4 Tax=Bacteria TaxID=2 RepID=A0A2E6N654_9BACT  ali  37  3...............TPQRKTKIVCTIGPSCFTQEGINSLLLHGMNVARINFSHGGYEIHERSIKFIRKAAREF-DYSIPVLADLQGPKIRIGQMKDEAQV-LQDGREITLTTEAII---GTADCVPIDYDKLPQEAEVGNTILLDDGLLEFKVTKCLEN-SLKVKVIVGGLLKSRKGVNLPNVKISIPALTPKDRKDLEFAVKMDADYIALSFVRKPQDVIDLKKLLRELGSEAGIIAKIEKPEAVDYIDAIIEQADGIMVARGDLGIEIPAEEVPFIQKTIIEKCRAAGKSVITATQMLDSMIKNPRPTRAETSDVANAVLDGTDAVMLSGETAVGKYPMDAVNVMDRICRKIEEHRIQLYNSLEYNKPSDPDKQIIESLAHTCVLLSEKADSTLISTITHSGSTARRIAKFRPKVPIFAFTESQKVRRQLNLVWGVRSIRLRELF------DTDISVKIMEDYLKENGQVKSGDRVVVATGMPTARGRTNMVKISII 476
671 0.000e+00UniRef50_E6W3W5 Pyruvate kinase n=5 Tax=Bacteria TaxID=2 RepID=E6W3W5_DESIS  ali  37  1.................MRKTKIVATIGPASNSKEAITSLIRAGLSVARLNFSHGTHSDHAEVIRTIREVSTEM-GIPVAILQDLQGPKMRTGKLRDATPVELRVGQTFTITIDDII---GDNEQVSTTYTPLPRDVKKGDRILLSDGLIELRVIS-ADDRSVQTEVLNGGTLAEKQGINLPGVQVSIPAITEKDYEDLCFGLEQEVDYIALSFVRSATDVQELKTIIAGKGKNTPIIAKIEKPEAVDRMEEILSIADGIMVARGDLGVELPPEQVPLIQKRIIHMANARAIPVITATQMLESMINNPRPTRAEASDVANAILDGSDAVMLSGETARGKYPVDAVRMMARIATEVERGMLQDHALRLEAMNFADVDAVPHAVGGAIEAISNRLPIKAVWVYTQKGGTARLASRHRPRIPVLAFTPHVSLYRRLSLLWGIHPVLIEPVHS------IEELMESARRISEYRGVVKTGDKVIITSSYPFEHGESNFLQIIT. 472
672 0.000e+00UniRef50_A0A2A8D1B1 Pyruvate kinase n=3 Tax=Bacteria TaxID=2 RepID=A0A2A8D1B1_9BACT  ali  36  3..................RRTKIVCTLGPASSDSETIENLIEAGMNVARMNFSHGSHDDHAERIHTVREAA-KRQGKTVTILQDLQGPKIRVGQMKDG-SVMLDEGQTLVITPDPV--EEGTAERVHIDYPTLAEDADIGGRILLDDGLLELKVTDIQ-GTDLITEVVEGGPLRSRKGVNLPNIRTSTPSLTEKDREDLKFGLSMDVDVVALSFVRERSDVEELLGLIEDAGNNVSIVAKIEKPEAVRNIEEILEVVDGIMVARGDLGIEMPMEEVPSTQKMLISRSMATARPVITATQMLESMVDNPRPTRAEASDVANAVLDGSDAVMLSAETAVGTDPVRVVQAMTKIIRRAERHWDFRQTLSMTPGHLERTENVTESVSFTACRLAEQVNAAAICCLTNSGATARSIARHRPSMPIYAFTDNQRVVGQLGMLWGTQSFHIP------FQQDTDQGIARVHSILRDQGLVEPGSHVVITAGMPLPAGRTNMVHVSRV 475
673 0.000e+00UniRef50_P52489 Pyruvate kinase 2 n=67 Tax=Eukaryota TaxID=2759 RepID=KPYK2_YEAST  ali  70  4.SRLQRLANLKIGTPQQLRRTSIIGTIGPKTNSCEAITALRKAGLNIIRLNFSHGSYEFHQSVIENAVKSEQQFPGRPLAIALDTKGPEIRTGRTLNDQDLYIPVDHQMIFTTDASFANTSNDKIMYIDYANLTKVIVPGRFIYVDDGILSFKVLQIIDESNLRVQAVNSGYIASHKGVNLPNTDVDLPPLSAKDMKDLQFGVRNGIHIVFASFIRTSEDVLSIRKALGSEGQDIKIISKIENQQGLDNFDEILEVTDGVMIARGDLGIEILAPEVLAIQKKLIAKCNLAGKPVICATQMLDSMTHNPRPTRAEVSDVGNAVLDGADCVMLSGETAKGDYPVNAVNIMAATALIAESTIAHLALYDDLRDATPKPTSTTETVAAAATAAILEQDGKAIVVLSTTGNTARLLSKYRPSCPIILVTRHARTARIAHLYRGVFPFLYEPKRLDDWGEDVHRRLKFGVEMARSFGMVDNGDTVVSIQGFKGGVGHSNTLRISTV 502
674 0.000e+00UniRef50_A0A1F8LVH0 Pyruvate kinase n=3 Tax=Chloroflexi TaxID=200795 RepID=A0A1F8LVH0_9CHLR  ali  38  7..............STPYRRTKIVCTMGPSTSSPSVIKELLKTGMDVARINFSHGTYDEHASYIKTLRQAAKQ-ADLPLAILQDLPGRKNRTGKLKRGIA-ELKADTEFTLTTREIL---GDEHKVTVGLPVLPSLVKPGDTIFLDDGAIELKVTSTR-NMEVNCQVVIGGSLSEDKGVNIPGMTWDTSTITEEDWAHLLFGLKHDIDLVALSFIREANDVLKVRNFIQKKKKAPALIAKIERREALDNLDEILEAADGAMVARGDLGIEIPIQRVPIVQKEIIQKCNRLGKPVIVATQMLESMVHALRPTRAEVTDVANAIFDGADALMLSEETAIGNYPVETVSMMAQIALEAEASLPYEDILSSKGKDLQPQTD--DAISYAACHAAHQLGAAAIIAFTSSGSTARRVAKYRPGVPILAITPSTETRRQLSISWGVRAFQIPEPSK------ISALFTQGARVAKRTGLAQDGDLVVITGGIPLGSGSTNLLKVERV 479
675 0.000e+00UniRef50_O08309 Pyruvate kinase n=138 Tax=Firmicutes TaxID=1239 RepID=KPYK_CLOAB  ali  42  1.................MQKTKMIFTVGPASETEEIVTAFIKAGMNASRHNFSHGDHAEHGGRIALVKKVRAKL-NKPVAICLDTKGPEIRTGDF-NPSKLELQKGSKFTIVCGEEIV--GDATKCSISYKDLYKDVKPGNTILIDDGLVGLTVEAI-EGTNVICTVANTGLVGSHKGVNVPNVSIQLPAMTEKDKSDLIFGCKEEIDMVSASFIRKPEDVLAIRKVLNENGGNIQIFSKIENQEGVDNIDAIIEVSDGIMVARGDMGVEIPIQRVPLIQKMIIKKCNAVGKPVITATQMLDSMMRNPRPTRAEASDIANAIFDGTDAIMLSGESANGSYPIEAVTTMAKIAQEAENEINYDKFLAERKGNEKK--NTSDVISLGTCTAAADLEASAIITATQTGSTARTVSKYRPKAPVIAVTPSEKVARKLAMSWGVHPIISDKFGS------TDELISTSVDKALEAGYVQKGDLVVVAAGVPTNSGTTNMLKVQVV 472
676 0.000e+00UniRef50_A0A2N1QUS0 Pyruvate kinase n=26 Tax=Bacteria TaxID=2 RepID=A0A2N1QUS0_9BACT  ali  41  6..................RKVKIICTMGPACWEEEIITQLVNSGMNVARLNFSHGDYASHTRTIDNVRKVEATLR-RPVATILDTKGPEIRTGMLPNHEKILLESGKEFYLFFEHVV---GNADGVYVDYPDLYKEVSVGQEIFIDDGSILLSV-EALDPAAIKCRVLVGGELGEKKGVNVPGANLSVPTLTDKDISDIRWGVEHKVDYIAVSFVRGKEDIIGVRKVLEENSGESKIIAKIETRHSVENIDEILAVVDGIMVARGDLGVEMPTEDVPMVQKEIIEKCRSQGKPAIVATQMLDSMIRNPKPTRAEASDVANAVIDGADAVMLSGETASGKYPVESVKIMNKILMRTEENLREWQRTPKIFFNC---GEIADAVSRAARDISETVCAAAILSLTRSGSTARMVSKYRPDCPVIALTPSFSTWRELALVWGVYPLVCP------FTTDVEESVSNSLSLVQEEGLIKGGDNVVFTSGIPLGPGSTNLVQVYTV 474
677 0.000e+00UniRef50_A0A0S7ZPE3 Pyruvate kinase n=1 Tax=Spirochaetes bacterium DG_61 TaxID=1704237 RepID=A0A0S7ZPE3_9SPIR  ali  39  1.................MKATKIVCTIGPKCHDESTIQQMTKAGMNIVRMNFSHGTYDFHDKTIRATRKVSQIL-GMHIGILMDLQGPKIRTGKLKKD-SVILHKGDRLTLITEDRV---GDWEELSVNYPQLPQEARIGERIFLDDGNIELKVIEVTE-KEVRCRIVNGGIIRSYRGINLPDTRISAPSLTEKDLADLNFGVDNGVDYVALSFVRKPDDVEDLRRQIQARGSDVPIVAKIEKPEAIRNLDRIIEVSDGIMIARGDLGAETSPQDVPIYQKLIIEKCNCAGKPVITATQMLESMMSHPRPTRAEASDVANAIFDGTDALMLSGETALGEYPVGAVKVMRRIAEKTERELRRQRCPAEERFFSEGRISIADAICSSATRMSDQLKPKFIVGFTLSGKTAHLMSKYRPSVPIIAMSPSETVLRRLSLYRGVHPIRID------MVENTEDLISAAERILVQKKLCREEDMVLIIGGVPVLAGPTNMLKAHRI 472
678 0.000e+00UniRef50_A0A2H5ZRY8 Pyruvate kinase n=7 Tax=Bacteria TaxID=2 RepID=A0A2H5ZRY8_9BACT  ali  39  6.............TPPRRRRTKIVATIGPATGEPDRLRALVEAGVDVMRFNFSHGTREEHRRWIQLVRRFSAEL-GRPVAILQDLQGPKIRVGELRDHRPVVLEEGSEVVI---GAHTEGGTAQRLSVTYPELVREVRAGDRILLADGELELAVTSVGP-EEVRARVVRGGLLEEHKGINLPGVSLRAPALTDKDVEDLRFGLEAGVDFVALSFVRRAEDVARARELMERLGRTVPLVAKLEKAEAVDHLEEIMQASDGVMVARGDLGVELAPERVPTLQKHIIRRANELGIPVITATQMLESMVDHPRPTRAEASDVANAILDGTDAVMLSAETAVGRYPLEAVRMMDRIAVEVEAASPQ---LYQAPRQHDRRLGIAEAVAAAACRLSHDLRAKAIVVITRSGRTAQLVSKNRPAEPIVALTEDELVARGLCLWWGVHPVVIE------FREDTDAMLTHAEEELLRRGLVEPGDVLVVTGSAPIARGRTNFVKVHRV 479
679 0.000e+00UniRef50_I0GM44 Pyruvate kinase n=12 Tax=Firmicutes TaxID=1239 RepID=I0GM44_SELRL  ali  41  2.................LKKTKIVCTQGPSTEKPGVIDALIANGMNCARFNFSHGDHEEHLGRINMVREAAKK-AGKVISLILDTKGPEMRLGEFKDGK-VMLEKGNQFTLTYDDV---PGDETHVSVNHKGLYTEVKPGDTLLLSDGLVALKVDEI-KGKDIVTTIQNSGKMSTRKRVAAPGVSLGLPPISEQDAKDIIFGCEQDMDFVAASFIQRPDDVLAIRKLIEEHNGRMEIIPKIENLEGVKNFDAILEVSDGIMVARGDLGVEVPAEDVPLIQKEIIRKCNAAGKPVIVATQMLDSMERNPRPTRAEVSDVGNAILDGTDAIMLSGETASGDYPVEAVSTMNRIAQRMESSLEYKELFVE--RGFQHMESRTRAIAHATVQMAYELDAPAIITPTESGYTTKVVSKYRPKAAIVAYTPSEKALRQLNLRWGVYPVL------GTMWNDVDEMISNATAAAVKEGLVERGDLTIITSGVKAGKGNSSSVRVYNI 470
680 0.000e+00UniRef50_A0A0M3QV83 Pyruvate kinase n=2 Tax=Schizophora TaxID=43738 RepID=A0A0M3QV83_DROBS  ali  43  113.SQLEHACLIRYNAKPAFRRTGIICTIGPASRSVEMLLKMLDTGMDIARLNFSHGTHEYHGETVANVRQAMAQYSKHNVAIALDTKGPEIRTGLIKGSAAVELATGAKFTLSTKQELQAEGTADQVYVDYKNITKVLKPNDRVYLDDGLISLIVKS-AEAEQLICEVENGGKLGSSKGVNLPNVNVDLPAVSEKDKCDLQFAVQQQLDIVFASFIRDAASIEEIRCILGEQGKHIKVIAKIENHQGMQHIKQIIDAADGIMVARGDLGIEIPAEKVFLAQKSMIALCNKVGKPVICATQMLESMIRKPRATRAELSDVANAVLDGSDCVMLSGETAMGDYPLQCISVMSKVCQEAESAIWHERCFQDLVNSASESRDYEQSLIVAAVHAAIQCQAKAIIVLTKTGRSAATLARFRPRCPIIVIEQNARVARQTRLYRGVIPINIAAKQTGKWLESIKQRISLALNIAKQRGFVQKGDPVIIVTGGKNKRAGINSMH.... 618
681 0.000e+00UniRef50_P51182 Pyruvate kinase n=271 Tax=Firmicutes TaxID=1239 RepID=KPYK_SPOPS  ali  41  1.................MRKTKIVCTIGPASESPELLEQLIEAGMNVARLNFSHGNHAEHKARIDSIRKVARE-KGKVVGILLDTKGPEIRTHSMMNGK-LELVTGQKIDISMTQV---EGNNDVFSVSYDKLIEDVNEGSVILLDDGLIQLEVTGKDVARLIHTLIINSGSLSNNKGVNIPGVSVQLPGMTEKDAEDILFGIREGVDFIAASFVRRASDVMEIRALLENNGSNLQIIPKIENQEGVDNIDEILNVSDGLMVARGDLGVEIPPEEVPLVQKNLIEKCNQAGKPVITATQMLDSMQRNPRPTRAEASDVANAIFDGTDAIMLSGETAAGIYPVESVQTMDRIALTTEAAIDYRSVVSTRRR--EKHGNMTEAIGQAAAYTAINLKVKAVLAPTESGHTAKMIAKYRPGCPVIAVTSSEMCSRKLSLIWGVYPIVGKK------ASSIDEILQESVEESVKHQYVGHGDVVIITAGVPVGAGTTNLMKIHVI 473
682 0.000e+00UniRef50_K8Z9I3 Pyruvate kinase n=40 Tax=Bacteria TaxID=2 RepID=K8Z9I3_9ENTE  ali  42  3.................MKKTKIICTIGPASESVDTLVELMNAGMNVCRLNFSHGDHEEQGNRIQNIRKAM-EISGKRVALLLDTKGPEIRTHLMKDGK-VEFSTGDIVRVSMTEV---EGTREKFSVSYEGLINDVEPGMHIMLDDGLIDLLVQELDANNEIVCEVQNEGILKNRKGVNVPNASIKLPALTEKDANDIRFGIEQGIDFIAASFVRRASDVLAIREILEENGQHIQIIPKIENQEGIDNADEILAVSDGLMIARGDMGIEIPVENVPSVQKMLIKKCNELGKPVVTATQMLDSMQSNPRPTRAEVTDVANAIYDGTDAIMLSGETAAGDYPVITVQTMARIAERTEEAIAEMGI--NKFSLPGDKNDITEAIGRSVVHTAKNTGIETIVAATVSGYTARKISKYRPNAYIVALTFSEQKARSLALTWGVYPQV------KEHPSNTDAMFALANEVAKESGFAKEGDTIIVTAGV-GEQGTTNLMKIQEV 473
683 0.000e+00UniRef50_P30615 Pyruvate kinase 1 n=27 Tax=Kinetoplastida TaxID=5653 RepID=KPYK1_TRYBB  ali  48  1MSQLEHNIGLSIFEPAKHRANRIVCTIGPSTQSVEALKNLMKSGMSVARMNFSHGSHEYHQTTINNVRAAAAEL-GLHIGIALDTKGPEIRTGLFKDGE-VSFAPGDIVCVTTDPAYEKVGTKEKFYIDYPQLTNAVRPGGSIYVDDGVMTLRVVSKEDDRTLKCHVNNHHRLTDRRGINLPGCEVDLPAVSEKDRKDLEFGVAQGVDMIFASFIRTAEQVREVRAALGEKGKDILIISKIENHQGVQNIDSIIEASNGIMVARGDLGVEIPAEKVCVAQMCIISKCNVVGKPVICATQMLESMTSNPRPTRAEVSDVANAVLNGADCVMLSGETAKGKYPNEVVQYMARICVEAQSATHDTVMFNSIKNLQKIPMCPEEAVCSSAVASAFEVQAKAMLVLSNTGRSARLISKYRPNCPIICVTTRLQTCRQLNVTRSVVSVFYDAAKSGE-DKDKEKRVKLGLDFAKKEKYASTGD....................... 475
684 0.000e+00UniRef50_A0A1Q7N4I3 Pyruvate kinase n=88 Tax=Bacteria TaxID=2 RepID=A0A1Q7N4I3_9BACT  ali  35  40.............SSPSLRRAKIICTVGPACDSEAMLRELMRLGMDVARLNFSHGTHQEHARNIQRLRRAAEKES-RSICILQDLQGPKIRTGRLKGHDPVLLKNGSRVTITPRDV---SGTPTLISTTFADLSREVRPGSRILLSDGLIELRVIRIR-GEDIECEVVNGGLLTEHQGINLPGTALKIPALSAKDRKDLEFGLNHGVDIVALSFVRSAADIRAVKQVMSGHRQEVPVIAKLEKPQALEHLEEIFEAADGVMVARGDLGVEMPPEKVPVIQKHVIRRSMQWRKPVIIATQMLESMIENPRPTRAEASDVANAVFDGTDALMLSAETASGMYPREAVTMMSKIVIEAESNMGE---FTQPRRREHRGLSVAETICESIAHAAEDLRMGAIAVFTESGNTARLISKYRPQAAIYAFSHLLPVCNRMNLLWGVHPMRRKQARSA------EEMMSTAEQELLRKGIIRTGDVVGVVAGTQMASGSTNFMRLHVV 512
685 0.000e+00UniRef50_D0MGU5 Pyruvate kinase n=145 Tax=Bacteria TaxID=2 RepID=D0MGU5_RHOM4  ali  36  3..................RRTKIVCTLGPASSDRETIRKLIEAGMDVARLNFSHGNHEEHRRRIEIVREEARKL-GRDVAILQDLQGPKIRLGEVAEGG-ILIHEGQRLVLTAHPERADG--QTRIFVNYPTLAQDVEPGGRILLDDGLLELKIVDV-EGEDVITEVVVGGPLRSRKGVNLPHLRNSTPSLTEKDLRDLEFGLQMEVDLIALSFVRSETDVADLMRRVRDSGKEVRVIAKIEKPEAVAKIDQILAQADGIMVARGDLGIEMPLAEVPAVQKRIIRKCLAAAKPVITATQMLESMIENPRPTRAEASDVANAVLDGSDALMLSGETATGKYPVRVVQVMDEIIRQAERFRRERGHWLHIPKGADEAESVTEAIGYTACQLAEQVGAVAIACLTATGSTARMIARHRPPVPVYAFTDNPRIVPQLSLLWGTRAFSIP------FQRDTDQGVQLVHRILKEQGLVRPGDLVVITAGMPPAKGRTNMVHVSRI 478
686 0.000e+00UniRef50_A0A2A2LBN6 Pyruvate kinase n=1 Tax=Diploscapter pachys TaxID=2018661 RepID=A0A2A2LBN6_9BILA  ali  51  1...................................MLQQMILNGMNIARLNFSHGSHEYHAGTITNVRVAAESFSDRSIGIALDTKGPEIRTGLLAGGAEIELIKGGSIRLTTDPKFQESGTAVNLYVDYKNISKVVSPGSRVYVDDGLISLIVDETTEDT-VVCTVENGGMLGSRKGVNLPGTIVDLPA-------DLQFGVEQGVDMIFASFIRSAEGIKTIRKVLGEKGKHIKIIAKIENQEGMDRADEIIMEADGVMVARGDLGIEIPAEKVFLAQKMLIAKCNLAGKPVICATQMLESMVKKPRPTRAEGSDVANAVLDGADCVMLSGETAKGDYPLEALKIMHFICKEAEAAIYQRKLFEELLFNTPKPTDMTQTIAIAAVSAAVSCHASSIIIITTTGRSAIQCSRYKPPVPIMTISRDEGVCRQLHLYRGIFPIFYNQSRDVDWPTDVDNRINNAIDVGKDRGFIHKGDLLVVVTGWKQGAGYTNTLRIITV 460
687 0.000e+00UniRef50_Q54RF5 Pyruvate kinase n=38 Tax=Eukaryota TaxID=2759 RepID=KPYK_DICDI  ali  44  1MATLSRNLRLSLDTPSTFVRTKIVCTIGPKTMSEEALIKLIETGMNVCRLNFSHGTHDYHGQVIKNVRSAMEK-TGKIIAIMLDTKGPEIRTGKIEDRGYVDLFVGQEILVDTN--MNQPGTSFRISIDYKGLLDSVKVGGYILIADGVISLSITAVEKEKHVVCRVNNNSRLGENKNVHLPGAIVNLPAVSEKDILDIKFGVEQNVDFIAASFIRKADDVNEIREILGEKGKDIQIISKIENVEGVDNFNEILEVSDGIMVARGDLGVEVQMEKIFVAQKMIVSKCNAAGKPVITATQMLESMIKNPRPTRAEATDVANAVLDGSDCVMLSGETASGDYPYEAVDIMAKICREAESSTDYQTLFAALKLSSAKPVSIAETVASYAVATAIDLKADLIITLTETGLTARLVSKYRPSIPIIAVTSWSYTVKHLLATRGAIPFLVESLVG------TDKLVESCLEYAMKHNLCKKGSRVVIVSGVMEGPGKTNSLRVLTV 498
688 0.000e+00UniRef50_A0A261CA86 Pyruvate kinase (Fragment) n=2 Tax=Caenorhabditis TaxID=6237 RepID=A0A261CA86_9PELO  ali  47  99.THMEHLCRLDIREAPHVRQTGIICTIGPACASVDMLQKMILNGMNIARLNFSHGSHEYHAGTIANVREAADSFSDKRIGIALDTKGPEIRTGLLAGGASIELKKGASIRLTTDQHFSESGTAINLFVDYKNISKVLEVGSRVYIDDGLISLIVEECQED-AVVCQVENGGMLGSRKGVNLPGTIVDLPAVSEKDIKDLQFGVEQGVDIIFASFIRNAEGIRTIRKVLGEKGKKIKIIAKIENQEGVDNADEIITESDGVM--------------------MLISKCNRAGKPVICATQMLESMVHKPRPTRAEGSDVANAVLDGADCVMLSGETAKGDYPIDALKIMHYICKEAEAAVYHRRIFDELLQSTPKPTDMSHTIAIAATSAAASCHASAILLITTTGRSAIQCSRYKPAVPILTISRDVAVCRQLHLYRGVFPVHYQAERAADWPTDVDNRINHAIAIGKDRGFIHRGDFLVVVTGWRQGAGATNTLRIIT. 579
689 0.000e+00UniRef50_B0TI28 Pyruvate kinase n=59 Tax=root TaxID=1 RepID=B0TI28_HELMI  ali  41  15...................RTKIVCTVGPASSDPTILMEMIRAGMRVARLNFSHGTYEEHAARIAAVRQAADAL-GQPIAILLDTKGPEIRLGQVSGGK-ITLDEGAEVTLFPDD--GTLGTKERLPISYAGLVEDVRPGVRVLIDDGNIEMEVTAVEAG-EIRCRIKNGGDVSSRKGVSVPGVALRMPAISEKEVKDLEFGIAQDMDFVAISFVRDASDVLGIRKILEDRGASMQLIAKIENHQGVDNIDEILAVSDGIMVARGDLGVAIPTEDVPLVQKMIIEKCNIAGKPVITATQMLDSMIRNPRPTRAEATDVANAILDGTDAIMLSGETAAGKYPVEAVTMMARIAIRTEQALRHDEELDRRRKAGLG--SVTDSISHATCSIAADLKAKAIITLTKAGSTARMVSRYRPDCPIIAATPETKVMRQMAVVWGAEPMKVRETAG------TDEMLGDAIDCALKEGRIESGDLVVVTAGVPVGSGTTNLLKVHV. 482
690 0.000e+00UniRef50_C5EEK3 Pyruvate kinase n=20 Tax=Clostridiales TaxID=186802 RepID=C5EEK3_9FIRM  ali  38  1.................MKKTKIICTMGPNTNDRNVMMELAKNGMDVARFNFSHGDYEEHQGRLELLKEVRKEL-DIPVAALLDTKGPEIRTGQLKDGKKVTLKEGQTYTLTTRELI---GDENIGYINYSGLGEDVVPGNKILIDDGLIEMDVMEVN-GTDIVCKVINGGELGEKKGVNVPNVKIKLPALTDKDKEDIRFGIKQGFDFIAASFVRTADCIREIKAMLDEQGSSMKVIAKIENAEGIENLDAIIEEADGIMVARGDMGVEIPAEKVPHIQKKIIRKCNEACKIVITATQMLDSMIRNPRPTRAEVTDVANAVYDGTDAVMLSGETAMGKYPVEALKMMVSIAEESESYLDY-AGYRQRKVSKQNMKNVSNAVCFASVSTSHDLSADVIIAPSITGFTTQMLSKWRPAARIIGMSPSMATVRQMQLQWGVVPI------WSRRAESTDELIENSVEELKERGLVTVGELAVITAGVVTYARRTNIMRVINI 477
691 0.000e+00UniRef50_A0A1C5ZEI2 Pyruvate kinase n=17 Tax=Bacteria TaxID=2 RepID=A0A1C5ZEI2_9FIRM  ali  41  1.................MRKTKIVCTIGPVTQSEEMIKKLMEHGMDVARFNFSHGSYEYHKDCIEKVRKVASEL-NLPVAAMMDTKGPEVRLGRFVDDKPVEIKNGDIYTLTTEDCL---CTDKVGSITFKKLPADVSVGTRILINDGVIELLA-EKVTATEIECRVIHGGKLSNNKGINVPGVKLSMPYLSDADMNDLEFAAKMKYDFIAASFVRTAADINYLRKYTQSLGWDVRIIAKIENLEGVENIDEILEAADGIMVARGDMGVEIPFEQIPAIQKELIHKGYNAGKQVITATQMLESMISNPRPTRAEITDVANAIYDGTSAIMLSGETAAGEYPIEAVSTMALIAETTEYNIDYKSRFH--KRGTDSNPNIANAISHACVTTAHDLDVKAIITVTKGGSTARLISKYRPLCPIISCTTDEVVCRQMNMSWGVTPIIINEETS------TDELFEHAVDAAKKYGYVEQGDRVVITAGVPLGSGTTNLMKVDTV 472
692 0.000e+00UniRef50_A0A2N0VFM5 Pyruvate kinase n=3 Tax=Bacteria TaxID=2 RepID=A0A2N0VFM5_9BACT  ali  39  6..................RRTKIVCTLGPSSNTKEDIERLYRAGMNVVRINFSHGTHEGHKQTIGYVREVAEKV-GYAIPVLMDLQGPKIRVGQMKDGAQV-IKTGDMVRLTSEEVV---GTSDLVPIDYPNLADDSQVGNQILIDDGLLELRIVKKGSDG-ILAKVVVGGVLKSRKGVNLPDVDISMSSLTEKDKKDLEFGLKVGVDYVAMSFVRSARDIQDVISRIRAAGSNAAIIAKIEKPEAVNVIDDIIEETDGIMVARGDLGIEIPSEQVPLVQKKIIEKCRVAGKPVITATQMLDSMINNPRATRAESSDVANAVLDGTDAVMLSGETAAGKYPVEAVKTMDKIIKSVEGNAAGLYYSLKYRKPDWKEKQIIESLAYSCVMIADNIEAKAISTITHSGNTARRIAKFRPRVPIVAFTESLIVRRQLNLVWGVQSVRLNEIF------DTDISVKLMEDYLRENGFVNSGDRVIIATGMPVKKGRTNMIKVSTI 476
693 0.000e+00UniRef50_B8E0P8 Pyruvate kinase n=5 Tax=Bacteria TaxID=2 RepID=B8E0P8_DICTD  ali  40  2.................LRKTKIVCTIGPASEREEILRELIKAGMNVARLNFSHGDYNVHGERIRLIRKLSEELE-TPIPILQDLQGPKIRVGEIENDK-VFLKDNEEIALTPKELV---GNEKLVSVSYPHLLEDINIGDRILIDDGLIELKVIDKKEDKLI-CHIIHGGYISSRKGVNFPDSTLRVSPLTEKDKKDVLFGIEKKVDFIALSFVQRASDILELKEFLELHDARIPVIAKIEKREAVNNFREILEVADGIMVARGDLAIEMSNEEVPLIQKKIIRETRLAGKPVITATQMLISMVNNPTPTRAEVSDVANAILDGTDAVMLSNETATGKYPVESVQIMDKIARRVEKEFPYDTFLQESNCHK----NITEAITFSTCQIAKEIEASAIVTATHSGFTARHISKYRPKAPIFAITHFPEVQRRLNLSWGVTPLLTEVFY------NTDEMFEKSTKILLQKNYVKRGDTIVITAGIPMGSGMTNLIKVHVI 469
694 0.000e+00UniRef50_A0A2H6ETU8 Pyruvate kinase n=5 Tax=Bacteria TaxID=2 RepID=A0A2H6ETU8_9BACT  ali  38  1.................MKRTKIIATLGPSSSSFKIIESLVQNGVDIVRLNFSHGTLEAHAKLIQIVRRISEKI-GRPIGILQDLQGPKIRIGEIRDGQ-IFLNDGQEIVITTEPV---EGTKEIISTTYKHLPKDVSPGDSILLDDGLIELQVRKVVSEK-VICKIIHGGPLSSYKGVNLPGVKLSIPSLTEKDMEGLKFGIEQKVDFVALSFVRSPMDVAHIKKIIEDENTDIPVVAKLEKPEAIKNLDEILSVTDAAMVARGDLGVEMNPEKVPIIQKEIIRKCIEKGIPVITATQMLESMRFHPKPTRAEASDVANAIFDGTDAVMLSGETASGAYPVESVQMMTKIIEEAERH-SQEDNRGFHRDKTHPRATFPDSISEAACDAALELNARAIVAFTQSGFTARLLSKYRPSTPIVAFTLTNKVQRRLLLNWGVLTRKIE------MINSLDEMIRRVEKALLSDDLVKPGDSVVIVSGAPLGVGTTNMMTLHRV 471
695 0.000e+00UniRef50_A0A1G5EQE1 Pyruvate kinase n=1 Tax=Desulfoluna spongiiphila TaxID=419481 RepID=A0A1G5EQE1_9DELT  ali  39  1.................MRRTKIVCTIGPTSESPDVLRNLIDSGMNVARLNFSHGSHDEHIKKIHTIRELSREM-GKPVAILQDLCGPKMRTGKI-EEPGIELVPGAELILTSEEIM---GVGNRVSVSYKDLPDEIKAGDVILLADGLMELVVKEI-KGQDITCTVVIGGLLTSNKGINLPTSVLKIPALTEKDKEDLAFGLENDVDFVALSFVKTVDDINEIKELIAAAGKATPVIAKIEKHEAIANIDEIMKATGGIMVARGDLGVEIPLEDVPGVQKMLVEKSVAAGKPVIIATQMLRSMVDSPRPTRAEATDVANAVLDGADAVMLSEETANGNFPVETVRYMSRIAAKAEETYPHKQFMKSVCKE-----RVSDSVSYAACVLAEKLSTSAIVAPTTSGFTARQISRFRPDSPIIALSPDEAAMRRLCLFWGCYPSLV------NSAEGMDEMIEQGASEALQTGLVDKGDTIVITAGYPTWPGTTNMVKV... 464
696 0.000e+00UniRef50_O44006 Pyruvate kinase n=104 Tax=Eukaryota TaxID=2759 RepID=KPYK_EIMTE  ali  42  41MSQLEHHEDEDFSAH----RTKIVCTMGPSCWDVDKMVQLIDAGMNVCRLNFSHGDHEAHGRVVKNLQEALKQRPGKRVALLLDTKGPEIRTGMLEGDKPIELHAGDMLKIVTD--YSFVGNKSCIACSYEKLPSSVKPGNTILIADGSLSVEVVECGKD-YVMTRVMNPAIIGNKKNMNLPGVKVDLPVIGEKDKNDINFGIPMGCNFIAASFVQSADDVRYIRSILGTKGRNIKIIPKIENVEGLLNFDEILQEADGIMIARGDLGMEIPPEKVFLAQKMMISKCNVAGKPVITATQMLESMTKNPRPTRAEAADVANAVLDGTDCVMLSGETANGSFPVQAVTVMSRVCFEAEGCIDYQQVFRATCQATMTPIDTQEAVARAAVETAQSINASLILALTETGRTARLIAKYRPMQPILALSASEETIKQLQVIRGVTTFLVPTFQG------TDQLIRNALSAAKELQLVSEGDSIVAVHGIKEEAGWSNLLKVLVV 530
697 0.000e+00UniRef50_A0A0K2SKC8 Pyruvate kinase n=1 Tax=Limnochorda pilosa TaxID=1555112 RepID=A0A0K2SKC8_9FIRM  ali  40  12.................LKRTKIICTIGPATESVDTLRAMVAAGMDLVRLNFSHGTLDEHRRRIEAVRRLQAEGAG--LAILQDIQGPKIRLGEVPGGR-VTLERGQEVEVSA--TLPPRAAPLRLSIPYPPLAEQLGPGSTLFLDDGEVELRV-EAVEGEALRCRVQVGGDLSSHKGVTLPGVRVGLPPITPQDEAHIRFGVEMGVDWVAASFVRAAEHVEAVRDAIRRAGGDQPVVAKVENRQGLEAIDEIIEAADAVMVARGDLGVEIPPEEVPMAQKMIIQKCNAAGKPVITATQMLDSMARNPRPTRAEVTDVANAILDGSDAVMLSGETAVGRYPVESVRMMAAICRRTEASINYAALLRERRP--RDGTSVAEAIAHATCQTAQTLGARAIVTSTQSGATARMVSRFRPESPIVAITPSSGVRRRLNLVWGVVPLLVPR------AESIDQMIDLGVAAARHQGLVSQGDVLVIAAGVKTGPGSTNLLQVHMV 481
698 0.000e+00UniRef50_A0A2A9PD34 Pyruvate kinase n=1 Tax=Ophiocordyceps unilateralis TaxID=268505 RepID=A0A2A9PD34_9HYPO  ali  63 1523..RINWLASLDTAYKPNYRRSSIICTIGPVTNSVEKINSLRDAGLNVVRMNFSHGTYDYHQSVIDAARKAVECHPGRPVAIALDTKGPEIRTGNTKDDADLPISAGTVLNITTDDKYAKTCDTENMYVDYKNITKVIEPGRIIYVDDGVLAFEVLSIKDDKTIQVRARNNGFISSRKGVNLPNTDVDLPALSEKDKADLQFGVKNKVDMVFASFIRRAQDIRDIRKVLGEQGKDIQIIAKIENRQGLNNFKEILEETDGVMVARGDLGIEIPAAEVFAAQKKLIAMCNLAGKPVICATQMLESMIKNPRPTRAEISDVGNAITDGADCVMLSGETAKGAYPTEAVREMHEACLKAENTIPYVSHFEEMCTLVQRPVSTVESCAMAAVRASLDLGAGGIIVLSTSGESARLLSKYRPVCPIFMVTRNATTSRFGHLYRGVYPFLFPEAKPDNWQEDVDRRIKWAVDQALKLKTLTIGDMVVVVQGWKGGMGNTNTLRIVR. 2025
699 0.000e+00UniRef50_H1XU02 Pyruvate kinase n=1 Tax=Caldithrix abyssi DSM 13497 TaxID=880073 RepID=H1XU02_9BACT  ali  38  8...................KAKIICTIGPASEDEDTLRKIIQAGMDVARLNFSHGTHEEHRQKIERIRKVAAAL-GKPVAIMQDLQGPKIRIGRFKN-PPVNLKPGNTFTITTRPIL---GDQSQVSTTYQNLPNDVKPGDVILVNDGLIKLRVQSKNA-TDVVCEVVNGGSLYDRRGINLPGVHISEPSLTDKDKEDVLFGLQQGIDYVALSFVRDAESIHELRAFMGERA--VPIIAKLEKPEALENLEAIIDASDGVMVARGDLGVEISTEKVPSVQKTIIEKCMLKNKPVITATQMLDSMMVHPIPTRAEAADVANAIYDGSDAVMLSGETAFGSYPIESVKTMNNIIKESEKHQQFFRLKPDDRIENLLQDFPT-SVCHSAYHSAFEIKARFIVVLTRSGFTALKMSNFRPEAPILALTTSPHTYRKMSLYWGVVPVLIENELF------LTEDLSELEQMLKSGNWVKRSDRLVIIAGSSRQQGGTNLLRLHQV 473
700 0.000e+00UniRef50_A0A1J8Q3M4 Pyruvate kinase n=1 Tax=Rhizopogon vesiculosus TaxID=180088 RepID=A0A1J8Q3M4_9HOMO  ali  62  829.SQLEWNSTLSVSNAPFLRKTAIIATIGPNTNTVEKLAALRRAGVNVVRMNFSHGSYDYHQSVIDNTRKLAEDPTGRPVAIALDTKGPEIRTGVMRDGKDLPIKAGHEFIVTTDDKYSEICDDKLLWFDYKNLPKVTAPGKMIYIDDGILSLLVLSI-DGPNVHVRAVNNGTLSSRKGVNLPKTEVDLPALSEKDKKDLRFGVKNGVDMIFASFIRRGQDVKDIRQVLGPDGASIKIIVKIENEQGVENFDEILRETDGVMVARGDLGIEIPASQVFLAQKMMIAKCNIAGKPVIVATQMLESMTYNPRPTRAEISDVANAVLDGSDCVMLSGETAKGSYPVESVLMMAETCLLAEAAICYPPLYDELRGIQPRPTETVETVAIAAVAAASEQNASAIIVLSTSGNTARLISKYRPRVPIITVTRNEQTARQIHLHRGCYPFWYPEPHESQWQKDVDNRIRFGLKNALALNIIKTGTTVIAVQGWKGGLGHTNTMRILSV 1337
701 0.000e+00UniRef50_A0A146H6V6 Pyruvate kinase n=1 Tax=Mycena chlorophos TaxID=658473 RepID=A0A146H6V6_9AGAR  ali  62  647.STLEWSSTLSIEDTKFLRKTSIIATIGPKTNSVEKLAELRRAGVNVVRMNFSHGSYEYHQSVIDNTRKVAAESDGRPVAIALDTKGPEIRTGLTKDGIDYTIPSGHEFIISTDPKYSESCDDKVMFVDYANLPKVTAPGKLIYVDDGILSLLVLSI-DGTNVHVRTLNNGTISSRKGVNLPKTAVDLPALSEKDKADLQFGVKNGVDMIFASFIRRAQDVKDIRTVLGPDGANIKIIVKIENEQGVANFDEILRETDGVMVARGDLGIEIPASQVFLAQKMMIAKCNIVGKPVIVATQMLESMTYNPRPTRAEVSDVANAVLDGADCVMLSGETAKGNYPIQSVLMMAETCLLAEAAICYPPLYAELTAIQPRPTETSETVAIAAVAAASEQNASAILVLSTSGNTARLISKFRPKVPIITVTRNEQTARQIHLHRGCYPFWYPEPRGHQWQTDVDNRIRFGLRNALKLKIITPGTTIIAVQGWRSGSGKSNSLRILSV 1155
702 0.000e+00UniRef50_P80885 Pyruvate kinase n=828 Tax=cellular organisms TaxID=131567 RepID=KPYK_BACSU  ali  43  1.................MRKTKIVCTIGPASESIEMLTKLMESGMNVARLNFSHGDFEEHGARIKNIREASKKL-GKNVGILLDTKGPEIRTHTMENGG-IELETGKELIISMDEVV---GTTDKISVTYEGLVHDVEQGSTILLDDGLIGLEVLDVDAKREIKTKVLNNGTLKNKKGVNVPGVSVNLPGITEKDARDIVFGIEQGVDFIAPSFIRRSTDVLEIRELLEEHNADIQIIPKIENQEGVDNIDAILEVSDGLMVARGDLGVEIPAEEVPLVQKELIKKCNALGKPVITATQMLDSMQRNPRPTRAEASDVANAIFDGTDAIMLSGETAAGSYPVEAVQTMHNIASRSEEALNYKEILSKRRDQV--GMTITDAIGQSVAHTAINLNAAAIVTPTESGHTARMIAKYRPQAPIVAVTVNDSISRKLALVSGVFA------ESGQNASSTDEMLEDAVQKSLNSGIVKHGDLIVITAGTVGESGTTNLMKVHTV 472
703 0.000e+00UniRef50_Q1CYU9 Pyruvate kinase n=20 Tax=Cystobacterineae TaxID=80811 RepID=Q1CYU9_MYXXD  ali  39  1.................MRRAKIVCTLGPASQSQEMLEALLENGMDVARLNFSHGSHEQHAENIAKLRAASLKVR-KAVGILGDLQGPKIRTGRFVKGST-ELKEGGTFHITTDETV--PGTDEIVSTTYPFLAADVNPGDRILLDDGLLELKVLETDKQKLIRTQVIHGGTLKNNKGINLPGVAVRAEALTPKDREDLVFGIKAGVDYIALSFVRQPSDLDTARQAMAEVGRTVPIIAKLEKPEAIARLDAILDKTDGVMVARGDLGVEIPPEEVPAVQKDIIRRSNLRGLPVIVATQMLNSMIDNPRPTRAEASDVANAVFDGADAVMLSGETASGKFPIESVQMMERIILAAESSARTTQLMRVLETPVGLPNHFPDVIARVACEAAKASNASLIAAFTLSGVTARLLSHYRPPVPIVAFSPNQEVRRRLSLLWGVVPRVLEPTQ------DTEAMVKRVEEELLARGLGRKGDRIVIVFGAPVGPGKINSLRLHTI 475
704 0.000e+00UniRef50_J7SC03 Pyruvate kinase n=1 Tax=Fibroporia radiculosa TaxID=599839 RepID=J7SC03_9APHY  ali  61  8.SRLQWFSSLQITQAPYHRKTSIIATIGPKVNSVEMLTKLIL------RMNFSHGSYEYHQSVIDNTRKVTSLMEGRPIAIALDTKGPEIRTGNMRNDVDIKISAGHEFIVSTDRKYYDICDDKVLYMDYANLPKVTAPGKLIYVDDGILSLLVLSV-DGTSVRVRAINNGTLSSHKGVNLPNTDVDLPALSEKDKADLRFGVKNGVDMVFASFIRTGKDVKDIREVLGPDGANIKIIVKIENLQGVENFDEILAETDGVMVARGDLGIEIPPSQVFLAQKMMISKCNIAGKPVIVATQMLDSMMQNPRPTRAEVSDVANAVLDGSDCVMLSGESAKGAYPIESVLMMAECCLLAEAMICYPPLYDELRFATSRPTETVETTAVAAVGAALEQNASAIIVLSTSGNTARLVSKYRPPVPIITVTRNQQTARQVHLYRGCYPFWYPEPRGHQWQTDVDNRIRFGLRNALKLNIIKTGTTVVALQGWKGGLGHTNTVRILSV 510
705 0.000e+00UniRef50_Q27686 Pyruvate kinase n=23 Tax=Eukaryota TaxID=2759 RepID=KPYK_LEIME  ali  47  1MSQLAHNLTLSIDPVANYRAARIICTIGPSTQSVEALKGLIQSGMSVARMNFSHGSHEYHQTTINNVRQAAAEL-GVNIAIALDTKGPEIRTGQFVGGDAVM-ERGATCYVTTDPAFADKGTKDKFYIDYQNLSKVVRPGNYIYIDDGILILQVQSHEDEQTLECTVTNSHTISDRRGVNLPGCDVDLPAVSAKDRVDLQFGVEQGVDMIFASFIRSAEQVGDVRKALGPKGRDIMIICKIENHQGVQNIDSIIEESDGIMVARGDLGVEIPAEKVVVAQKILISKCNVAGKPVICATQMLESMTYNPRPTRAEVSDVANAVFNGADCVMLSGETAKGKYPNEVVQYMARICLEAQSALNEYVFFNSIKKLQHIPMSADEAVCSSAVNSVYETKAKAMVVLSNTGRSARLVAKYRPNCPIVCVTTRLQTCRQLNITQGVESVFFDADKLG-HDEGKEHRVAAGVEFAKSKGYVQTGDYCVVIHADHKVKGYANQTRILLV 498
706 0.000e+00UniRef50_Q6GG09 Pyruvate kinase n=514 Tax=root TaxID=1 RepID=KPYK_STAAR  ali  43  1.................MRKTKIVCTIGPASESEEMIEKLINAGMNVARLNFSHGSHEEHKGRIDTIRKVAKRL-DKIVAILLDTKGPEIRTHNMKDG-IIELERGNEVIVSMNEV---EGTPEKFSVTYENLINDVQVGSYILLDDGLIELQVKDIDAKKEVKCDILNSGELKNKKGVNLPGVRVSLPGITEKDAEDIRFGIKENVDFIAASFVRRPSDVLEIREILEEQKANISVFPKIENQEGIDNIEEILEVSDGLMVARGDMGVEIPPEKVPMVQKDLIRQCNKLGKPVITATQMLDSMQRNPRATRAEASDVANAIYDGTDAVMLSGETAAGLYPEEAVKTMRNIAVSAEAAQDYKKLLSDRTKLV--ETSLVNAIGISVAHTALNLNVKAIVAATESGSTARTISKYRPHSDIIAVTPSEETARQCSIVWGVQPVV------KKGRKSTDALLNNAVATAVETGRVTNGDLIIITAGVPTGEGTTNMMKIHLV 472
707 0.000e+00UniRef50_A0A0L1HN22 Pyruvate kinase n=1 Tax=Stemphylium lycopersici TaxID=183478 RepID=A0A0L1HN22_9PLEO  ali  67  169.TRIEWLSQLNTEYTPEYRRTSIICTIGPKTNSAEKINALRKVGLNVVRMNFSHGSYEYHQSVIDHAREAEKTQLGRPLAIALDTKGPEIRTGNTVGDADIPIKAGATINITTDEQYASACDDKNMYVDYKNITKVMEAGRTIYVDDGVLSFEVLEITDDKTLKCKCVNNGKISSRKGVNLPKTDIDLPPLSEKDKADLRFGVKNKVDMVFASFIRRGSDITAIREVLGEEGKDIQIIAKVENQQGVNNFDEILRETDGVMVARGDLGIEIPPSQVFIAQKMMITKCNIAGKPVICATQMLESMTYNPRPTRAEVSDVGNAVLDGADCVMLSGETAKGDYPVEAVTMMHETCLLAEVAIPYVNAFDELRKLAPVPCPTTETCAMAAVSASLEQNAGAILVLTTSGTTARLVSKYRPVCPIIMVTRNEMAARYSHLYRGVYPFYFPEFKTEPWQEDVDRRLKWGIMNAIK--LVNDGDATVL................... 653
708 0.000e+00UniRef50_A0A1V5QEU6 Pyruvate kinase n=6 Tax=Bacteria TaxID=2 RepID=A0A1V5QEU6_9BACT  ali  40  1.................MRMTKIVCTLGPASNTPERIEQLLRAGMNVARLNFSHGTQDEKGRTIRQLRSISARL-GMPVAILEDLAGPKIRTGVIENE-PIQLESGQAFILTGRKV---RGNAKEVSLSYPNLPKDVKKGDTILLSDGALELVVREVV-GKDIRCRVVVGGPLSSRKGVNLPGGSLSVPILTAKDRSDLGFGLAQGVDYVALSFVRTAEDVEQVRRLMKRIGKSAPLIAKIEKHEAVANIDRILEVVDGVMVARGDLGVEIPIEDVPRVQKMVIAKANRAGKPVITATQMLKSMVDSPRPTRAEVTDVANAILDGSDAVMLSEETAAGSYPVQAVQVMSRIARATEKDFPYRLWTSKFDHH--GPLDSQMAVAHAACRLAEEIHAAAVVTCTQSGSTTRMVSRYRPPMPILAMTPDRTTYHRMGLVWGAAPVRMKPAR------DADAMEREAVRLAVQHGYVRPGQAVVITAGLPLHPGTTNLVKVVT. 469
709 0.000e+00UniRef50_A0A075AZ21 Pyruvate kinase n=30 Tax=Opisthokonta TaxID=33154 RepID=A0A075AZ21_9FUNG  ali  53  22.TRLSWIAGINVDQHPVIRKTSIICTIGPKTNSPKVMADLRKAGMNIARLNFSHGSHEYHATAVQNVRDSFKLYDGRPVAIALDTKGPEIRTGNLKDEGGILIPEGHVFLITTDDKRMNDGDLDTIYMDYKNLPSAVKVNGKIFVDDGILSLTVLEC-SGNTVKVKANNSHRLLNHKGVNLP------------DAEDLKFAVKHNLDMIFASFIRKPEDVIEIRKILGEQGKDIKIISKIESTEGLKNFDDILEVSDGIMVARGDLGIEIPPEKVFLAQKMIIARCNIVGKPVICATQMLESMTQNPRPTRAEVADVSNAILDGSDCVMLSAETARGTYPVETVQMMHKIVIEAESTISYVPLFEELRNLSFQSSGPTETIACAAVNASLEDYIEAIIVLTTTGESARFVAKFRPAVPIITVTRSEFVARQIHLSRGCYPLYYEEKKISSWQDDVDARISYAVTQGKKMGLLKPNSHVVVIQGHQGGHGNTNTMKVIQV 508
710 0.000e+00UniRef50_Q02499 Pyruvate kinase n=514 Tax=root TaxID=1 RepID=KPYK_GEOSE  ali  41  3..................RKTKIVCTIGPASESVDKLVQLMEAGMNVARLNFSHGDHEEHGRRIANIREAA-KRTGRTVAILLDTKGPEIRTHNMENGA-IELKEGSKLVISMSEVL---GTPEKISVTYPSLIDDVSVGAKILLDDGLISLEVNAVDKAGEIVTTVLNGGVLKNKKGVNVPGVKVNLPGITEKDRADILFGIRQGIDFIAASFVRRASDVLEIRELLEAHDAHIQIIAKIENEEGVANIDEILEAADGLMVARGDLGVEIPAEEVPLIQKLLIKKCNMLGKPVITATQMLDSMQRNPRPTRAEASDVANAIFDGTDAVMLSGETAAGQYPVEAVKTMHQIALRTEQALEHRDILS--QRTKESQTTITDAIGQSVAHTALNLDVAAIVTPTVSGKTPQMVAKYRPKAPIIAVTSNEAVSRRLALVWGVY------TKEAPHVNTTDEMLDVAVDAAVRSGLVKHGDLVVITAGVPVGEGSTNLMKVHVI 474
711 0.000e+00UniRef50_Q6FV12 Pyruvate kinase 2 n=81 Tax=Eukaryota TaxID=2759 RepID=KPYK2_CANGA  ali  84  3.SRLHRLINLEVTPGKDVRKTAIIGTIGPKTNNVDTLVALRKAGLNIVRMNFSHGSYEYHQSVIDNARKSEQVYPGRPLAIALDTKGPEIRTGTNVDDVDYPIPPNHEMIFTTDDKYAKACDDKIMYVDYKNITKVIQPGKVIYVDDGVLSFEVLEVVDDKTLKVKSLNAGKISSHKGVNLPGTDVDLPALSEKDKEDLRFGVKNGVHMIFASFIRTAQDVLTIREVLGEEGKDIKVIVKIENQQGVNNFDEILEVAHGVMVARGDLGIEIPAPQVLAVQKKLIAKCNLAGKPVICATQMLESMTFNPRPTRAEVSDVGNAILDGADCVMLSGETAKGNYPINAVTTMAETAIIAERAIAYMPLYDDLRNCTPKPTSTTETVAASAVAAVQEQGAKLILVLSTSGNTARLVSKYRPQCPIVLVTRNPRTARFSHLFRGVFPFVYEKEPLDDWSEDTHARLRFGVDMAKEYGFVKNGDAVISIQGFKGGVGHSNTMRVSIV 501
712 0.000e+00UniRef50_P14618-3 Isoform 3 of Pyruvate kinase PKM n=97 Tax=Opisthokonta TaxID=33154 RepID=P14618-3  ali  68  16......NSELDIPAVN--RRTSIICTIGPKSNNVETLCKLRDAGMNIVRMNFSHGSYEYHQSVIDNARKASATNPLFPLAIALDTKGPEIRTGLTVGGTDYPISSGHEMIFTTDDAYAEKCNDKVMYIDYKNITKVIQPGRIIYVDDGILSFTVIEKVDDKNLKVRVNNNGKISSKKGVNLPKTDVDLPALSEKDKADLRFGVKNGVDMIFASFIRRAEDVIHIREVLGEEGKNIKIICKIENQQGVNNFDSILDVTDGIMVARGDLGIEIPASQVFVAQKMMIAKCNIAGKPVACATQMLESMTYNPRPTRAEVSDVGNAVLDGADLVMLSGETTKGSYPVEAVTYMAETARVAEASIPYGSLYQEMFGLVRRPLEATETTAVAAIGASIESDAKAIVVLSTSGNTARLCSKYRPSIPIVMVTRCPQRARQSHLNRGVYPVIYEKEPLSDWQKDVDARVAYGCQQAYKMNILKKGDKIIVLQGAVGGKGHTSIFRL... 505
713 0.000e+00UniRef50_A3LUJ3 Pyruvate kinase n=92 Tax=Opisthokonta TaxID=33154 RepID=A3LUJ3_PICST  ali  72  4.SSLAWLSQLNTTDTPDLRRSSIIGTIGPKTNSVEVLVKLRKAGLNIVRMNFSHGSYEYHQSVIDNAKKSEEVYVGRPLAIALDTKGPEIRTGTTVDNVDYPIPPNHEMIFTTDDAYKTKSDDKIMYIDYANITKVIEVGRIIYVDDGVLSFEVLEIVDEKTLKVKSINAGKVCSHKGVNLPGTDVDLPALSEKDKADIRFGVKNGVHMIFASFIRTGDDIKEIRRVLGEDGKQIQIIAKIENQQGVNNFDDILAETDGVMVARGDLGIEIPAPQVFVVQKQLIAKCNLAAKPVICATQMLESMTYNPRPTRAEVSDVGNAILDGADCVMLSGETAKGDYPFEAVSMMHNTAIIAEKAISYQSLHNELRVLAKKPTPTSETCAVAAVSAAYEQDAKAIVVLSTSGLSARLVSKYKPNVPIMMVTRNETSARYSHLYRGVYPFIYTKEKVANWQEDVENRLRWAVSEAIELGIIHKGDSIVTVQGWTRGSGHSNTVRIVQ. 503
714 0.000e+00UniRef50_D5GI89 Pyruvate kinase n=19 Tax=Opisthokonta TaxID=33154 RepID=D5GI89_TUBMM  ali  66  7.TQYQWLSQLNVDHVPNFRRTSIICTIGPKTNSVESINKLRKAGLNIVRMNFSHGSYEYHQSVIDNSREAERQHPGRPLAIALDTKGPEIRTGNTKGDADLPISAGSEIIITTDDKYVTSCTEKIMYVDYKNITK------------------VLDVTDERNIKARCLNNGKISSKKGVNLPKTDVDLPPLSEKDKEDLRFGVKNGVHMVFASFIRRGSDITAIREVLGEDGKEIQIIAKIENQQGVNNFDEILEETDGVMVARGDLGIEIPPAQVFIAQKMMIAKCNLAGKPIICATQMLESMTYNPRPTRAEVSDVGNAVLDGADCVMLSGETAKGNYPIESVTMMHETCLLAETAISYVPLFNELRGLTKRPTETSETCAIAAVSASVEQEASAIIVLSTSGSTARLISKYRPSCPVLMITRNANAARYSHLYRGVYPFVYPKPKPDFWQEDVDERLRWGTSEAIKLGLVKAGDTIIAVQGWRGGLGNTNTLRVL.. 492
715 0.000e+00UniRef50_A0A1X7R7A7 Pyruvate kinase n=5 Tax=Opisthokonta TaxID=33154 RepID=A0A1X7R7A7_9SACH  ali  87  3.SRIQRLTNLEVVAGKQLRKTAIIGTIGPKTNNPEVLVNLRKAGLNIVRMNFSHGSYEYHQSVIDNARKSEELYPGRPLAIALDTKGPEIRTGTTVNDVDYPIPPNHEMIFSTDDKYAKACDDKVMFVDYKNITKVISKGKIIYVDDGVLSFEVLEVVDGQTLKVKSLNAGKICSHKGVNLPGTDVDLPALSEKDKEDLRFGVKNGAHMIFASFIRTAQDVLTIREVLGEDGKDIKIIVKIENQQGVNNFDEILSVTDGVMVARGDLGIEIPAPEVLAVQKKLIAKCNLAGKPVICATQMLESMTYNPRPTRAEVSDVGNAILDGADCVMLSGETAKGNYPINAVTTMADTALIAESAIAHLPLYDDLRNSTPKPTSTTETVAASAVAATFEQGAQAIIVLSTSGTTPRLLSKYRPECPIILVTRNERAARMAHLNRGVFPFVYTKAAGSDWTEDVDARVQFGIQKAQELNILKKGDTFVSVQGFKAGSGHSNTLQVSTV 501
716 0.000e+00UniRef50_A0A151GKL6 Pyruvate kinase n=1 Tax=Drechmeria coniospora TaxID=98403 RepID=A0A151GKL6_9HYPO  ali  62  26..RINWLASLDTAYSPNYRRSSIICTIGPKTNSVEAINRLRDAGLNVVRMNFSHGSYEYHQSVIDNARKAVDTHPGRPVAIALDTKGPEIRTGNTKNDEDLPIAVGKVLNITTDDKYATSCDTDNMYVDYKNITKVIQPGRIIYVDDGVLAFDVLSIKDEKTIEVRARNNGFISSRKGVNLPNTDVDLPALSEKDKADLKFGVKNKVDMIFASFIRRAQDIKDIRAVLGDEGKQIQIIAKIENRQGLNNFKEILDETDGVMVARGDLGIEIPAAEVFAAQKKLIAMCNIAGKPVICATQMLESMIKNPRPTRAEISDVGNAITDGADCVMLSGETAKGSYPVEAVREMHEACLKAENSIPYVSHFEELCTLVKRPVRTVESCAMAAVRASLDLTAGGIIVLSTSGESARLLSKYRPVCPIFMVTRNATTSRFTHLYRGVYPFLFPEAKPDNWQEDVDRRIKWAVNHALELGTLTVGDTVVVVQGWKGGMGNTNTLRIVQ. 528
717 0.000e+00UniRef50_UPI0000D5551D pyruvate kinase n=1 Tax=Tribolium castaneum TaxID=7070 RepID=UPI0000D5551D  ali  45  32.TQLDHNSLLDIQSPPQVRLTGIICTLGPSTTDVETLERMIEAGMNIARLTLSHGTQEMHTELIQNVRTAVENYSKRPLSLALDIKGPEVRTGYMEGGAEVELKKGEQIKLTTDKAYLEKGSSSVIYVDYDNIQKVVQPGNRIFLDDGLISLICTSVQ-GSVLTCSVENGGMLGSCKNVNLPGIDIDLPVVSEKDKEDLLFGVEHGIDTVHASFIRNAVDVSEVRDVLGRAGNKILIISKIENHQGVHNIDEIIKASDGIMIGRGDLAVEIGPEKLFLAQKSIIAKCNKAGKPVICANQLLYSMIKRPRPTRAECTDVANAVLDGVDCVMLTGETFLGQHPIECIRAASKICKEAEGAIWYKHHFRELIGHARPPLETSHTICIAAVEAANQCLAAAIIVTSVSGRSAHSLAKYRPNCPIILVTRDPTVAKQANLFRGIIPLFYEVERKDDWRRDIEARISFGISFGKWRGFVRSGDPIVAVNGSQRGSGYTDTIRVLYV 537
718 0.000e+00UniRef50_A0A1H8MJI4 Pyruvate kinase n=196 Tax=Bacteria TaxID=2 RepID=A0A1H8MJI4_9BACL  ali  42  1.................MRKSKIVCTIGPASESLENIKKLILAGMNVARLNFSHGDFEEHGARIKNIRQACKEL-NKTVAILLDTKGPEIRTGKLEVE-PIELVQDEYLTLTTEEIL---GDKNRISVTYSNLPSDVQVGSTILIDDGLIGLTVVDIQ-GTEIKTRIVNGGTIKSKKGVNVPGVAISLPGITEKDTNDIIFGIEQDIDFIAASFVRKASDVKEIRDLLEKHNSHIQIISKIENQQGVDNLDEILAVSDGLMVARGDLGVEIPAEDVPLAQKLMIQKCNIAGKPVITATQMLDSMQRNPRPTRAEASDVANAIFDGTDAIMLSGETAAGKYPVESVLTMSRIAEKAESALNHREIF--LKQQIAQETTVTEAISQSVAISALDLSAKAIISSTVSGHTARVVSKYRPVSPIIAVTTQERTMRQLALVWGVTPVH------GSPASSTDELLETAVQGGKDSGLVKAGDLVVITAGIPLGSGSTNLVKVEQI 471
719 0.000e+00UniRef50_A7RER9 Pyruvate kinase n=43 Tax=Opisthokonta TaxID=33154 RepID=A7RER9_NEMVE  ali  47  28.SNLEFRSELDIDKHPTIRNSGVVCTIGPASRSVEIVAQLIENGMNIARLNFSHGTHEYHRETIMNIRRAALLEWPHAVGIALDTKGPEIRTGLLKAGE-IKLEKGQKLKVSTDKAMYDQGHTECIFVDYENIVKVVQIGGTVYVDDGLISLKVLEKG-DNFLITEVLNDALLGSKKGVNLPNCAVDLPAVSEQDKKDIAFAVEMEVDMIFASFIRKPEDIAEIRKLLEKHAKNIKIVAKIENHEGVRRFNEILEVADGIMVARGDLGIEIPAEKVFLAQKMMIARCNMKGVPVICATQMLESMVQNPRPTRAETSDVANAILDGADCVMLSGETAKGLYPVQAVAMMHRISREAEAAIFHKQSFDELRHNLEGYADTHISTAIAAVAASFTAGADAIICLTHTGRTAAVVARFRPRCPIVVVTRDPRVARQMHLWRGCFPIVYDQEPLDNVLEEHDQRLDFALGMGKKMGFLTIGSTFVFVSGWKSGAAHTNTLRILT. 524
720 0.000e+00UniRef50_J9B351 Pyruvate kinase (Fragment) n=3 Tax=Bilateria TaxID=33213 RepID=J9B351_WUCBA  ali  50  12.TNLEHLCKLNIEQPCVVRKTGIICTIGPACRSVEKLQEMIISGMNIARMNFSHGSYEYHAETIANVRSAAHSFSERLVAIALDTKGPEIRTGLLKGGAEVELVKGNRIRLTTDPSMENAGTAQNIFVDYKNITKVLSVGSRVFIDDGLISLIVNSI-EDEGILCTVENGGMLGSRKGVNLPGTPVDLPAVSEKDIKDLQFGVEQKVDIVFASFIRSGRGVSMIRKVLGEKGKYIKIIAKIENQEGVDKADEIIEEADGVMVARGDLGIEIPPEKVFLAQKMLIAKCNKAGKPVICATQMLESMIKSPLPLLYEGSDVANAVLDGADCVMLSGETAKGEYPLEALKIMHQICKEAEAAVYHTRFFEELLHATPKPTDIAHTVAIAATSAAASCHASAMILVTTTGRSADLVSRYRPMMPVFAICRDEHVARQLHLWRGIFPLHYGANRESDWSSDVDARINYGISVGKDRGFIKKNDLVVVITGWRQGAGHTNTLRIIK. 541
721 0.000e+00UniRef50_A0A238FSE1 Pyruvate kinase n=1 Tax=Microbotryum intermedium TaxID=269621 RepID=A0A238FSE1_9BASI  ali  64  9.SQLEWLTTLSIPPKKNLRKTSIIATIGPKTNSVEMISKLRTAGVNVVRMNFSHGSYEYHQSVIDNTRKAEASAEGRPLAIALDTKGPEIRTGNMVNDEDVKIPAGHRMLFSTDPKYATACTDKVYFIDYANLPKVIDVGKPIYIDDGVMSFRVLSI-KGTDVHVEAINAGTLSSKKGVNLPGTDVDLPAISQKDKDDLSFGVKNGVDMVFASFIRRDQDVKDIRAHLGEAGKNIKIIVKIENLQGVANFDEILKETDGVMVARGDLGIEIPASQVFMAQKMMIAKCNLAGKPSICATQMLESMTYNPRPTRAEVSDVANAVIDGADCVMLSGETAKGMYPIAAVEMMAETCFLAESAICYPPLFNEIRNLALRPTATSETVAMSAVAAALEQNAGAILVMSTSGNTARLISKYRPPCPVITITRNAQTARQVHLHRGCYPMLYEEPRPSSWQTDIDNRIRYGLSKALDLGVLKKGDTIVAIQGWRAGGGSSNTMRVLSV 543
722 0.000e+00UniRef50_A0A1Y2EFF0 Pyruvate kinase n=7 Tax=Opisthokonta TaxID=33154 RepID=A0A1Y2EFF0_9PEZI  ali  62  23...IEWLANLDTAYKPNLRRTSIICTIGPKTNSVEAINKLRTAGLNVVRMNFSHGSYEYHQSVIDNARAAEKAQPGRQIAIALDTKGPEIRTGNTKNDEDLPLKAGTIMNITTDEKYATSCDTENMYVDYKNITKVIDVGKIIFVDDGIIALEVLEIVDDKTIKVKAKNNGFISSKKGVNLPNTDVDLPALSEKDKNDLRFGVKNNVDMVFASFIRRGQDIKDIREVLGEDGKHIQIIAKIENRQGLNNFKEILDETDGVMVARGDLGIEIPAAEVFAAQKKLIAMCNTAGKPVICATQMLESMIKNPRPTRAEISDVGNAVTDGADCVMLSGETAKGSYPNEAVHEMHEACLQAENTIPYVQHFNELSTLAKPPVSIVESCAMAAVQQSLRINAGGILVLSTSGDSARLLSKYRPVCPIFMVTRSATTSRNGHLHRGVYPFYFPEEKPDNWQEDVDRRIKWGISNALDLNVISRGDTIVVVQGWKGGMGNTNTIRIVK. 524
723 0.000e+00UniRef50_P00549 Pyruvate kinase 1 n=107 Tax=Fungi TaxID=4751 RepID=KPYK1_YEAST  ali  100  1MSRLERLTSLNVVAGSDLRRTSIIGTIGPKTNNPETLVALRKAGLNIVRMNFSHGSYEYHKSVIDNARKSEELYPGRPLAIALDTKGPEIRTGTTTNDVDYPIPPNHEMIFTTDDKYAKACDDKIMYVDYKNITKVISAGRIIYVDDGVLSFQVLEVVDDKTLKVKALNAGKICSHKGVNLPGTDVDLPALSEKDKEDLRFGVKNGVHMVFASFIRTANDVLTIREVLGEQGKDVKIIVKIENQQGVNNFDEILKVTDGVMVARGDLGIEIPAPEVLAVQKKLIAKSNLAGKPVICATQMLESMTYNPRPTRAEVSDVGNAILDGADCVMLSGETAKGNYPINAVTTMAETAVIAEQAIAYLPNYDDMRNCTPKPTSTTETVAASAVAAVFEQKAKAIIVLSTSGTTPRLVSKYRPNCPIILVTRCPRAARFSHLYRGVFPFVFEKEPVSDWTDDVEARINFGIEKAKEFGILKKGDTYVSIQGFKAGAGHSNTLQVSTV 500
724 0.000e+00UniRef50_A0A1V4JCL5 Pyruvate kinase n=2 Tax=Patagioenas fasciata monilis TaxID=372326 RepID=A0A1V4JCL5_PATFA  ali  48  61.TFLEHMCRLDIDSEPTIRNTGIICTIGPASRSVDKLKEMIKSGMNVARLNFSHGTHEYHEGTIKNVREATESFTYRPVAIALDTKGPEIRTGLIKGSAEVELKKGAQLKVTLDDAFMENCDENVLWVDYKNLIKVIDVGSKIYVDDGLISLLVKEKGKD-YVMTEIENGGMLGSKKGVNLPGAAVDLPAVSEKDIQDLKFGVEQNVDMVFASFIRKAADVHAVRKVLGEKGKNIKIISKIENHEGVRRFDEIMEASDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNRAGKPIICATQMLESMIKKPRPTRAEGSDVANAVLDGADCIMLSGETAKGDYPLEAVRMQHAIAREAEAAMFHRQLFEEILRLNVNHRDPADAMAAGAVEASFKCLARALIVMTESGSLRRLTSKCCSGAIIVAVTRNDQTARQAHLYRGIFPVLCKDPAHSSWAEDVDLRVNLGMNVGKARGFFKSGDLVIVLTGWRPGSGYTNTMR.... 623
725 0.000e+00UniRef50_B7WNA0 Pyruvate kinase n=6 Tax=Chromadorea TaxID=119089 RepID=B7WNA0_CAEEL  ali  49  411.THMEHLCRLDIREAPHVRQTGIICTIGPACASVEMLQKLILNGMNIARLNFSHGSHEYHAGTIANVREAADSFSDKRIGIALDTKGPEIRTGLLAGGASIELARGASIRLTTDPHFSESGTAVNLFVDYKNIAKVLSVGSRVYIDDGLISLIVEELQTD-AVICSVENGGMLGSRKGVNLPGTIVDLPAVSEKDCKDLQFGVEQGVDIIFASFIRNAEGIRTIRKVLGEKGKKIKIIAKIENQEGVDNADEIISESDGVMVARGDLGIEIPAEKVFLAQKMLISKCNRAGKPVICATQMLESMVHKPRPTRAEGSDVANAVLDGADCVMLSGETAKGEYPVDALKIMHYICKEAEAAVYHRRLFDELLQNTQKPTDMSHTIAIAATSAAASCHASAILLITTTGRSAIQCSRYKPAVPILTISRDVAVCRQLHLYRGVFPVHYPAERAADWPTDVDNRINHAIAIGKDRGFIHKGDFLVVVTGWRQGAGATNTLRIIT. 911
726 0.000e+00UniRef50_A0A0L0CGM6 Pyruvate kinase (Fragment) n=2 Tax=Lucilia cuprina TaxID=7375 RepID=A0A0L0CGM6_LUCCU  ali  41  565....................................IVKMIRAGMTIVRLNFSHETHELHAETIRLLHNVEEECSKIQLAIALDTKGPEIRTGLLEAGPQVELKVNDSVRLSINRDLMDKGNRECIYVDYEKIIDVVQPGNLVYINDGLIKLIVKDVGVD-CVTCQVERGGMLGSRKKINLPGISVDLPAVSKKDVSDLKFALEHKIDFIFASSMRNASAVKEVRSLLGDQGKCVKIIAKIDCEQGLHNVDEILSVADGILFASADIAIEINIVKVFLAQKAVIARCNRAGKPIILATKLLESMRYSIFPTKAEVSDLGNAILDGVDCVLLSSETAIGQFPSESIAYMCAICREAELALWNRHMFEDILLRNPTILDAAHSIAIAAVDAAKKSSASAIVVLTASGKSSYLLAKYRPRCPILAVTKCPRTFRQSHLYHGVIPVMYTEIAQKSWLNEVDARVQFCMYVANRMNIIKGGDSVVILSPWKDGGGFTNTMRII.. 1032
727 0.000e+00UniRef50_A0A226BQB2 Pyruvate kinase n=52 Tax=Opisthokonta TaxID=33154 RepID=A0A226BQB2_CRYNV  ali  63  66.SQLAWLSGLSTNDQKFLRKTSIIATIGPKTNNVDTLVQLADAGMNIVRMNFSHGSYEYHQSVIDNARAAAAKSSGRPIAIALDTKGPEIRTGLMKDDIDVPISAGHEFWVTTDKAYAEAGTAEQIYIDYTNIVKVTAPGKLIYVDDGILSLQVISIQ-GEKIRVKSLNSGVLSSRKGVNLPKTAVDLPALSEKDKSDLAFGVKNSVDMIFASFIRSANDVKEIRKVLGPEGADIKIIVKIENEQGVMNFDEILRETDGVMVARGDLGIEIPASQVFMAQKMMIAKCNVAGKPVICATQMLESMTYNPRPTRAEVSDVANAVIDGADCVMLSGETAKGKYPIEAVKMMAETAFLAESSIAYPPLFDQLRALTPRPTETAETLALSAVAAAIEQDAGAIIVLSTSGVSARLISKYRPACPIICVTRNEQTARQLHLSRGVYPVWFPEPRGEKWQIDVDNRIRYGLRMALGLGIIKPEATVMAVQGWKGGLGHTNTLRILSV 573
728 0.000e+00UniRef50_A0A197K8X8 Pyruvate kinase n=31 Tax=Fungi TaxID=4751 RepID=A0A197K8X8_9FUNG  ali  64  8.TNLEWTSALDIDQPTNTRKTSIICTIGPKTNSVEMLSKLRDAGMNIVRMNFSHGSYEYHQSVIDNTRKSCEVHPGRPVGIALDTKGPEIRTGLMKDDVEVPILAGHKMIITTDEKYAEACTGDHMYVDYKNLPKVITPGKIIYVDDGVLSFKVLEV-DGTNVMVEAINNGKICSRKGVNLPKTDVDLPALSEKDKKDLLFGVKNNVDIIFASFIRRAEDIREIRKVLGEEGKHIKIICKIENHQGVKNFDEILEETDGVMVARGDLGIEIPCAQVFLAQKMMISKCNLAGKPVICATQMLESMTYNPRPTRAEVSDVANAVLDGADCVMLSGETAKGSYPLEAVRTMDETCILAESAICYPPLFNELRQLQKRPVETTETVASSAVSASQEQKAGAIVVLSTSGDTARLVSKYRPQANIIIVTRKESTARAIHLSRGCYPFIYKEPKSQDWQEDVDKRLRWGMDQAIEVGLLKAGEPVVVIQGFRSGYGNTNTMRII.. 548
729 0.000e+00UniRef50_P30614 Pyruvate kinase n=11 Tax=Opisthokonta TaxID=33154 RepID=KPYK_YARLI  ali  68  11.TNLQWLSTLNTDDIPNYRKSSIIGTIGPNTNSAEMISKLRQAGLNIVRMNFSHGSYEYHQSVIENARESEQQFQGRPLAIALDTKGPEIRTGVTKDDKDWDVKAGHVMLFSTNPKYKDQCDDKIMYIDYTNIVKQIDIGKIIFVDDGVLSFKVLEKIDGETLKVETLNNGKISSRKGVNLPGTDVDLPALSEKDKADLKFGVEHGVDMIFASFVRTANDVQAIRDVLGEKGKGIQVISKIENQQGVNNFDEILKETDGVMVARGDLGIEIPAPQVFIAQKQLIAKCNLAGKPVICATQMLDSMTYNPRPTRAEVSDVGNAVLDGADCVMLSGETAKGTYPIESVKMMHETCLVAEKAIAYAPLFNEMRTLTVRPTETVETIAISAVSASFEQQARAIIVLSTSGTSARLCSKYRPNCPILMVTRNAQAARFSHLYRGVYPFIYHKARASNWQHDVEERLKWGMDEAVALGILNKGDVVVAIQGWTGGLGHTNTLRVLE. 513
730 0.000e+00UniRef50_A0A1I8GFK1 Pyruvate kinase n=1 Tax=Macrostomum lignano TaxID=282301 RepID=A0A1I8GFK1_9PLAT  ali  48  29.SHLEHLCRLDIDDPAYVRNTGIICTIGPACKSVAVLHKMIAAGMNIARMNFSHGTHEYHKETVELVRQAADTFKGRPVAIALDTKGPEIRTGLIGGSAEVELKRGSEIVVTTDPAHSENCSADMLWVDYPNIVKVVREGGRVFVDDGLISLLVKEVR-DNSLLCEVENGGNLGSKKGVNLPGAPVDLPAVSEKDKSDLRFAVEMGLDIVFASFIRNAEAIREIKHILGEEGKNIKIIAKIENHEGVRRFDEIMEAADGIMVARGDLGIEIPPEKVFLAQKMMIGRCNRAGKPVICATQMLESMITKPRPTRAEISDVANAVLDGADCVMLSGETAKGSYPLEAVKTMHQVCREAESAMFSSQLFEDLKAELLEPTDITHTTAIAASEAANRCRAAAIIVITTTGRSASLISRHRPRCPILTVSRLAQTCRQAHLF---------PPRCEQWTEDMDKRIDFAIDYGRKREFINVGDFVVIVTGWKAGAGFTNTLRIVQV 522
731 0.000e+00UniRef50_A0A068X587 Pyruvate kinase n=1 Tax=Hymenolepis microstoma TaxID=85433 RepID=A0A068X587_HYMMI  ali  48  485.SLLEHICNLNIDEPYAIRNTSIICTIGPACRSVETLQKMMTAGMNIARLNFSHGSHEYHLETIKLIRQAVETFKFRPVAIALDTKGPEIRTGLIDGSGEVTLECGEKIRITPNKEYENKCSKSILYMDYERIVHVLDVGSKVFIDDGLICLAVQEKGPD-YLDCVIENGGKLGSRKGVNLPGAPVDLPSMSEKDKGDLQFAVENNLDIIFASFIRSKQGIQEIREFLGEKGAHIKIIAKIENHQGVKLFDEIVQAADGIMVARGDLGIEIPPEKVFLAQKMAIARCNLVGKPVICATQMLESMTYKPRATRAESSDVANAVLDGADCVMLSGETAKGSYPVEAVQTMANICREAESAMFHGQLFDDLKSVLALPTDATLTTAIAAVEASNRCLAQAVIVITTSGRTAQLIARHRPRCPIITVTRHAIIARQLHLFRACHPIFYGEPRTELWAEDMDRRISCAIDYGRKRRFLNDGDNVVVVTGWKAGSGATNSLRIIQ. 986
732 0.000e+00UniRef50_P22360 Pyruvate kinase n=490 Tax=Opisthokonta TaxID=33154 RepID=KPYK_EMENI  ali  66  16...LEWHSKLNTEPAKNFRRTSIICTIGPKTNSVEKINALRRAGLNVVRMNFSHGSYEYHQSVIDHAREAEKQQAGRPVAIALDTKGPEIRTGNTVGDKDIPIKAGHEMNISTDEQYATASDDQNMYVDYKNITKVISAGKLIYVDDGILSFEVLEVVDDKTLRVRCLNNGNISSRKGVNLPGTDVDLPALSEKDISDLKFGVKNKVDMVFASFIRRGSDIRHIREVLGEEGREIQIIAKIENQQGVNNFDEILEETDGVMVARGDLGIEIPAPKVFIAQKMMIAKCNIKGKPVICATQMLESMTYNPRPTRAEVSDVANAVLDGADCVMLSGETAKGNYPCEAVTMMSETCLLAEVAIPHFNVFDELRNLAPRPTDTVESIAMAAVSASLELNAGAIVVLTTSGNTARMISKYRPVCPIIMVSRNPAATRYSHLYRGVWPFYFPEKKPDFWQEDVDRRLKWGINHGLKLGIINKGDNIVCVQGWRGGMGHTNTVRVV.. 516
733 0.000e+00UniRef50_B7Q0D5 Pyruvate kinase n=31 Tax=Bilateria TaxID=33213 RepID=B7Q0D5_IXOSC  ali  50  18.TLLEHLSTLDINQPSFVRLTGIICTIGPASKDVPVLVNMMKAGMNIARLNFSHGTYEYHAGTIKNVREAERKPDTRHVAIALDTKGPEIRTGLLKGGPSVELVKGEMITITTDPSFKESCDEKTLYVDYENITKVLNVNSKIFIDDGLISVVVKQVGP-VSLECFIENGGMLGSKKGVNLPGALVDLPAVSEKDKQDLLFGVEQGVDMIFASFIRNAAGVKEIRSVLGEKGKDIKIICKIENDEGVRKIDEIIDETDGIMVARGDLGIEIPPEKVFLAQKMMIAKCNMVGKPVICATQMLESMVKKPRPTRAEASDVANAVLDGADCVMLSGETAKGDYPLETVQIMHAICVEAEAAFYQKDVFIHLSHIAPCPTDGTHTIAIAAVSASIKCLASAIVVITTTGRTAHLIAKYRPRCPILAISRVEQTIRQSHLYRGILPLLYSGDRHPDWPMDVDSRIEYALEIGKSRGFLRKDDAVIVVTGWRKGAGATNTLRIVYV 524
734 0.000e+00UniRef50_E2AJ75 Pyruvate kinase n=1 Tax=Camponotus floridanus TaxID=104421 RepID=E2AJ75_CAMFO  ali  46  576.NQLDHMCALDTDSRSFIRLSGIICTIGPASRSVEMLEKMIETGMNIVRLNFSHGSHEYHAKTIVNVRQAQKNLTARPVAIAIDTTGSEIRTGLLEGGAEVELVKGQTFKLSTDEAYMKKGNAQVVYISYKNISKVLKIGTRIFVDDGLISLIVSDISPD-LISTTVEYGGMLGSRKGVNLPGVAVDLPTVSEKDKSDLQFGIDQEIDMIFVSFTRNAAAISEIRSILGEKGKGIKIVAKIENEQGRTNLDEIIDASDGIMVERGDLGVEIPPQKVFLAQKAMISRCNKVGKPVICATQMLESMVKKPRATRAETSDVANAILDGADCVMLSGETAKGDYPLECVHTMANICKEAEAAIWQTQIFHDLLSKVVPPIDAAHAVAIAAVEISVKCLASAIIVITTSGRSAHLISKYRPRCPIIAVTRFSQVARQMHLYRGILPLYYEGASLADWIKDVDTRVQYGFKFGKKRGFVRTGDSVIVLTGWQEGSGFTNTLRVV.. 1079
735 0.000e+00UniRef50_A0A2G7ELV2 Pyruvate kinase (Fragment) n=1 Tax=Aspergillus arachidicola TaxID=656916 RepID=A0A2G7ELV2_9EURO  ali  66  469...LEWHSKLNTEPAKNFRRTSIIGTIGPKTNSVEKINALRRSGLNVVRMNFSHGSYEYHQSVIDNAREAARVQTGRPLAIALDTKGPEIRTGNTTDDKDIPIKEGHELNITTDEKYATASDDQNMYLDYKNITNVIAPGKLIYVDDGILSFQVLEVVDDKTLRVKCLNNGNISSRKGVNLPGTDVDLPALSEKDISDLKFGVKNGVDMIFASFIRRGSDIRHIRDVLGEEGKEIQIIAKIENQQGVNNFDEILEETDGVMVARGDLGIEIPAPKVFIAQKMMIAKCNIKGKPVICATQMLESMTYNPRPTRAEVSDVANAVLDGADCVMLSGETAKGSYPCEAVKMMSETCLLAEVAIPHFNVFDELRNLAPRPTDTVESIAMAAVSASLELNAGAIVVLTTSGNTARLLSKYRPVCPILMVTRNPRASRYSHLYRGVWPFLFPENKPDFWQEDVDRRLKWAISHGIKLGIINKGDNIVCVQGWRGGQGHTNTVRVV.. 969
736 0.000e+00UniRef50_B0WL21 Pyruvate kinase n=12 Tax=Neoptera TaxID=33340 RepID=B0WL21_CULQU  ali  51  22VSHLEHMCSLDIDQTSFVRLSGIICTIGPASVAPEMLEEMMKTGMNIARLNFSHGSYEYHGNTIKNIREAVASYSAKPLAIALDTKGPEIRTGLIEGSGEVELKKGEKIELTTNKDHLEKGNKDKIYVDYVNIVKVVKPGDRVFVDDGLISLVANSISGDT-LTCTVENGGLLGSRKGVNLPGVPVDLPAVSEKDKADLQFGVDQGVDVIFASFIRNAAALKEIRGILGDKGKNIKIISKIENQQGMQNLDAIIAASDGIMVARGDLGIEIPAEKVFLAQKSIIARCNRAGKPVICATQMLESMIKKPRPTRAEISDVANAIIDGADCVMLSGETAKGEYPLECVLTMAKTCKEAEAALWHRNLFNDLVNTTPTPIDTGASIAIAAAEAASKIRAAALIVITTSGRSAHVISKYRPRCPIIAVTRFDQTARQCHLYRGILPVVYEQPPLEDWLKDVDARVQYGMEFGKERGFLKPGMPVVIVTGWKQGSGFTNTIRVVNV 528
737 0.000e+00UniRef50_O62619 Pyruvate kinase n=294 Tax=Eumetazoa TaxID=6072 RepID=KPYK_DROME  ali  49  28.TQLEHMCRLQFDSPPHVRLSGIVCTIGPASSSVEMLEKMMATGMNIARMNFSHGSHEYHAATVANVRQAVKNYSAKPVAIALDTKGPEIRTGLIGGSAEIELKKGEKIKLTTNKEFLEKGSLEIVYVDYENIVNVVKPGNRVFVDDGLISLIVREVGKD-SLTCEVENGGSLGSRKGVNLPGVPVDLPAVSEKDKSDLLFGVEQEVDMIFASFIRNAAALTEIRKVLGEKGKNIKIISKIENQQGMHNLDEIIEAGDGIMVARGDLGIEIPAEKVFLAQKAMIARCNKAGKPVICATQMLESMVKKPRPTRAEISDVANAVLDGADCVMLSGETAKGEYPLECVLTMAKTCKEAEAALWHQNLFNDLVRGA-GTIDASHAAAIAAVEAATKAKASAIVVITTSGKSAFQVSKYRPRCPIIAVTRFAQTARQAHLYRGLVPLIYKEPGLGDWLKDVDVRVQFGLQVGKKNGFIKTGDSVVVVTGWKQGSGFTNTIRIVTV 532
738 0.000e+00UniRef50_F7ANK4 Pyruvate kinase n=103 Tax=Vertebrata TaxID=1261581 RepID=F7ANK4_HORSE  ali  49  80.TFLEHLCLLDIDSEPAARSTSIIATIGPASRSVELIKEMIKAGMNIARFNFSHGSHEYHAESIANVRKAAESLSYRPVAIALDTRGPEIRTGILQGGSKVELVKGSQVLVTVDPAFQIQGNANTVWVDYPNIVRVMPLGSHIYIDDGLISLRV-KKIGPKGLETEVESGGLLGSRKGVNLPGIQVDLPGLSEQDVQDLRFGVEHGVDIVFASFMRKASDVVAVRAALGPKGQGIKIISKIENHEGVKKFDEILEVSDGIMVARGDLGIEIPAEKVFLAQKMIIGRCNLAGKPVVCATQMLESMITKSRPTRAETSDVANAVLDGADCIMLSGETAKGNFPVEAVKMQHAIAREAEAAVYHRQLFEELRRAAPLSRDPTEVVAIGAVEAAFKCCAAAIIVLTTTGRSAQLLSRYRPRAAVIAVTRSAQVARQAHLCRGVFPLLYHEPPEAIWADDVDRRVQFGIESGKLRGFLHVGDLVIVVTGWRPGSGYTNIMRVLSI 585
739 0.000e+00UniRef50_A0A182H1Q2 Pyruvate kinase n=1 Tax=Aedes albopictus TaxID=7160 RepID=A0A182H1Q2_AEDAL  ali  51  6VSHLEHMCSLDIDSQTFVRLSGIICTIGPASVAPEMLEKMMATGMNIARLNFSHGSHEYHANTIKNIREAVDNYSKKPLAIALDTKGPEIRTGLIEGSGEVELKKGEQIQLTTDKDHLEKGSKEKIYVDYVNIVKVVKKGDHVFVDDGLISLVVDSISGDT-LTCTVENGGMLGSRKGVNLPGVPVDLPAVSEKDKSDLQFGVEQGVDVIFASFIRNAAALKEIRSILGDKGKNIKIISKIENQQGMQNLDAIIAASDGIMVARGDLGIEIPAEKVFLAQKSMIARCNRAGKPVICATQMLESMIKKPRPTRAEISDVANAIIDGADCVMLSGETAKGEYPLECVLTMAKTCKEAEAALWHRNLFNDLVNTTPNPLDTACSIAIAASEAASKSRAAAVIVITTSGRSAHLISKYRPRCPIIAVTRFAQTARQCHLYRGILPVVYEQQALEDWLKDVDARVQYGMDFGKERGFLKPGNPVVVVTGWKQGSGFTNTIRIVYV 512
740 0.000e+00UniRef50_P30613 Pyruvate kinase PKLR n=432 Tax=Bilateria TaxID=33213 RepID=KPYR_HUMAN  ali  49  68.TFLEHLCLLDIDSEPAARSTSIIATIGPASRSVERLKEMIKAGMNIARLNFSHGSHEYHAESIANVREAVESFAGRPVAIALDTKGPEIRTGILQGGPEVELVKGSQVLVTVDPAFRTRGNANTVWVDYPNIVRVVPVGGRIYIDDGLISLVVQKIGPEGLV-TQVENGGVLGSRKGVNLPGAQVDLPGLSEQDVRDLRFGVEHGVDIVFASFVRKASDVAAVRAALGPEGHGIKIISKIENHEGVKRFDEILEVSDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNLAGKPVVCATQMLESMITKPRPTRAETSDVANAVLDGADCIMLSGETAKGNFPVEAVKMQHAIAREAEAAVYHRQLFEELRRAAPLSRDPTEVTAIGAVEAAFKCCAAAIIVLTTTGRSAQLLSRYRPRAAVIAVTRSAQAARQVHLCRGVFPLLYREPPEAIWADDVDRRVQFGIESGKLRGFLRVGDLVIVVTGWRPGSGYTNIMRVLSI 573
741 0.000e+00UniRef50_Q0D2C2 Pyruvate kinase n=60 Tax=Opisthokonta TaxID=33154 RepID=Q0D2C2_XENTR  ali  49  21.TFLEHMCRLDIDSEPIVRNTGIICTIGPASRSVEILKEMIKSGMNIARLNFSHGTHEYHAGTIKNVREATESFSYRPVAVALDTKGPEIRTGLIKGSAEVELKKGATLRITLDDAFQEKCDENILWVDYKNLTKVVKPGSKIYVDDGLISLLVKETGADFCL-TEVENGGMLGSKKGVNLPGAAVDLPAVSTKDIQDLQFGVEQNVDMVFASFIRKAADVHAVRKVLGEKGKNIKIISKIENHEGVRRFDEILEASDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNRAGKPVICATQMLESMIKKPRPTRAEGSDVANAVLDGADCIMLSGETAKGDYPLEAVRMQHAIALEAEAAAFHRQLFEELFRATASSKDPAEAMALGAVEASFKCLASALIVMTESGRSAHLVSRYRPRAPIIAVTRNGQTARQAHLYRGIFPVLYREAVHEAWAEDVDMRVNFAMDIGKARGFFKSGDVVIVLTGWRPGSGFTNTMRVVPV 526
742 0.000e+00UniRef50_F1SHL9 Pyruvate kinase n=80 Tax=cellular organisms TaxID=131567 RepID=F1SHL9_PIG  ali  50  25.TFLEHMCRLDIDSPPTARNTGIICTIGPASRSVETLKEMIKSGMNVARLNFSHGTHEYHAETIKNVRAATESFAYRPVAVALDTKGPEIRTGLIKGSAEVELKKGATLKITLDNAYMEKCDENVLWLDYKNICKVVDVGSKVYVDDGLISLLVKQKGPD-FLVTEVENGGFLGSKKGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMVFASFIRKAADVHEVRKVLGEKGKNIKIISKIENHEGVRRFDEILEASDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNRAGKPVICATQMLESMIKKPRPTRAEGSDVANAVLDGADCIMLSGETAKGDYPLEAVRMQHLIAREAEAAIYHLQLFEELRRLAPITSDPTEAAAVGAVEASFKCCSGAIIVLTKSGRSAHQVARYRPRAPIIAVTRNHQTARQAHLYRGIFPVVCKDPVQEAWAEDVDLRVNLAMNVGKARGFFKKGDVVIVLTGWRPGSGFTNTMRVVPV 530
743 0.000e+00UniRef50_P52480 Pyruvate kinase PKM n=313 Tax=Bilateria TaxID=33213 RepID=KPYM_MOUSE  ali  50  25.TFLEHMCRLDIDSPITARNTGIICTIGPASRSVEMLKEMIKSGMNVARLNFSHGTHEYHAETIKNVREATESFAYRPVAVALDTKGPEIRTGLIKGSAEVELKKGATLKITLDNAYMEKCDENILWLDYKNICKVVEVGSKIYVDDGLISLQVKEKGAD-FLVTEVENGGSLGSKKGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMVFASFIRKAADVHEVRKVLGEKGKNIKIISKIENHEGVRRFDEILEASDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNRAGKPVICATQMLESMIKKPRPTRAEGSDVANAVLDGADCIMLSGETAKGDYPLEAVRMQHLIAREAEAAIYHLQLFEELRRLAPITSDPTEAAAVGAVEASFKCCSGAIIVLTKSGRSAHQVARYRPRAPIIAVTRNPQTARQAHLYRGIFPVLCKDAVLNAWAEDVDLRVNLAMDVGKARGFFKKGDVVIVLTGWRPGSGFTNTMRVVPV 530
744 0.000e+00UniRef50_H9GHQ2 Pyruvate kinase n=97 Tax=Metazoa TaxID=33208 RepID=H9GHQ2_ANOCA  ali  49  25.TFLEHMCRLDIDSPPTARNTGIICTIGPASRSIEMLREMIKSGMNVARLNFSHGTHEYHAGTIKNVREATESFSYRPVAIALDTKGPEIRTGLIKGSAEVELKKGATLKLTLDNAFMENCDENVLWVDYKNITKVVEIGSKIYVDDGLISLQVKEKGAD-FLITEIENGGMLGSKKGINLPGAAVDLPAVSEKDIQDLQFGVEQGVDMVFASFIRKAADVHAVRKVLGEKGKNIKIISKIENHEGVRRFDEVMEASDGIMVARGDLGIEIPTEKVFLAQKMMIGRCNRAGKPIICATQMLESMIKKPRPTRAEGSDVANAVLDGADCIMLSGETAKGDYPLEAVRMQHLIAREAEAAIYHRQLFEELFRLTVNNRDPLDAIAVGAVEASFKCLAAAVIVLTESGRSAHLVSRYRPRAPIIAVTRDAQTARQAHLYRGIFPVLCKEPTHDSWAEDVDLRVNMGMDVGKARGFFKPGDLVIVLTGWRPGSGYTNTMRVVPV 530
745 0.000e+00UniRef50_P11980-2 Isoform M2 of Pyruvate kinase PKM n=319 Tax=Euteleostomi TaxID=117571 RepID=P11980-2  ali  48  25.TFLEHMCRLDIDSPPTARNTGIICTIGPASRSVEILKEMIKSGMNVARLNFSHGTHEYHAETIKNVRAATESFAYRPVAVALDTKGPEIRTGLIKGSAEVELKKGATLKITLDNAYMEKCDENVLWLDYKNICKVVEVGSKVYVDDGLISLLVKEKGAD-FLVTEVENGGSLGSKKGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMVFASFIRKASDVHEVRKVLGEKGKNIKIISKIENHEGVRRFDEILEASDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNRAGKPVICATQMLESMIKKPRPTRAEGSDVANAVLDGADCIMLSGETAKGDYPLEAVRMQHLIAREAEAAMFHRKLFEELVRGSSHSTDLMEAMAMGSVEASYKCLAAALIVLTESGRSAHQVARYRPRAPIIAVTRNHQTARQAHLYRGIFPVVCKDPVQEAWAEDVDLRVNLAMNVGKARGFFKHGDVVIVLTGWRPGSGFTNTMRVVPV 530
746 0.000e+00UniRef50_UPI000948493E poly [ADP-ribose] polymerase 6 isoform X5 n=1 Tax=Felis catus TaxID=9685 RepID=UPI000948493E  ali  48  590.TFLEHMCRLDIDSPPTARNTGIICTIGPASRSVEILKEMIKSGMNVARLNFSHGTHEYHAETIKNVRAATESFAYRPVAVALDTKGPEIRTGLIKGSAEVELKKGATLKITLDNAYMEKCDENVLWLDYKNICKVVEVGSKVYVDDGLISLLVKEKGAD-FLVTEVENGGSLGSKKGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMVFASFIRKASDVHEVRKVLGEKGKNIKIISKIENHEGVRRFDEILEASDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNRAGKPVICATQMLESMIKKPRPTRAEGSDVANAVLDGADCIMLSGETAKGDYPLEAVRMQHLIAREAEAAMFHRKLFEELVRGSSHSTDLMEAMAMGSVEASYKCLAAALIVLTESGRSAHQVARYRPRAPIIAVTRNHQTARQAHLYRGIFPVVCKDPVQEAWAEDVDLRVNLAMNVGKARGFFKKGDVVIVLTGWRPGSGFTNTMRVVPV 1095
747 0.000e+00UniRef50_P14618 Pyruvate kinase PKM n=250 Tax=Bilateria TaxID=33213 RepID=KPYM_HUMAN  ali  50  25.TFLEHMCRLDIDSPPTARNTGIICTIGPASRSVETLKEMIKSGMNVARLNFSHGTHEYHAETIKNVRTATESFAYRPVAVALDTKGPEIRTGLIKGSAEVELKKGATLKITLDNAYMEKCDENILWLDYKNICKVVEVGSKIYVDDGLISLQVKQKGAD-FLVTEVENGGSLGSKKGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMVFASFIRKASDVHEVRKVLGEKGKNIKIISKIENHEGVRRFDEILEASDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNRAGKPVICATQMLESMIKKPRPTRAEGSDVANAVLDGADCIMLSGETAKGDYPLEAVRMQHLIAREAEAAIYHLQLFEELRRLAPITSDPTEATAVGAVEASFKCCSGAIIVLTKSGRSAHQVARYRPRAPIIAVTRNPQTARQAHLYRGIFPVLCKDPVQEAWAEDVDLRVNFAMNVGKARGFFKKGDVVIVLTGWRPGSGFTNTMRVVPV 530
748 0.000e+00UniRef50_A0A011MYX0 Pyruvate kinase n=6 Tax=Candidatus Accumulibacter TaxID=327159 RepID=A0A011MYX0_9PROT  ali  33  1.................MRRTKIVATIGPATADTGSLRDLLEAGVDVVRLNAAHADMETHSANVRRVRELSQVL-GRSIGTLVDLPGPKIRSGVIACGE-VELANGQEFVLSGSDD--GQGDERHVATTLNDLAQWVCPGDDVYLADGAIVLRVLQSLGD-DVRTEVVRGGTLRSRKGMHLPRAEAHVEPFTERDALALEMAIAAKVDFIGLSFVRRAEDVERVRAMLPKRGVRPALVPKIETATAIDNLDGIIRTADAVMVARGDLGIQMPARSVPLLQKEIIRHCNLAGKPVITATQMLESMTRSPLPTRAEVNDVANAVLDGTDALMLSEETAVGLYPSQAVRMMSEVAESAEGWPRQRVAPEA---SGADGDRVAWAVAHAAVQAAEELGVAAILCPTRSGQTAHRVAAFRPNVPIAGISTSSQVLGDLSLVWGVRPLVVAANS------DPGEQLRLAVVAARGAGLVREGDLLAFVFGSAPRAGSTDSVRIVRV 470
749 0.000e+00UniRef50_A0A0P1ACF6 Pyruvate kinase n=1 Tax=Plasmopara halstedii TaxID=4781 RepID=A0A0P1ACF6_9STRA  ali  38  22............PTTARARKTKIICAIGPASWSVDMLGQLLDAGMNVARLNFSHGDHDLHNRSLLNLRKAMAARPGCHCAVLLDTKGPEIRTGLLRDHEPVQLKAGQTLEITTD--YSVEGDSSRIACTYELLPTSVSMGSKILCDDGSLVMTVLQCLSN-SIVVRVHNDHILEEKKNMNLPGAAIQIPGITEKDENDLNFAIPNGVDIVSGSFVRTAETVRAIRKCLGEAGRHIRVHAKIESLEALQNIDEIIAEADGIH--------------------MIIGKANKAGKPVVTSTQMLQSMTSKIIPSNAECTDVANAVLDGTDAMMLSAETAKGMYPKEAVETMAKICIEAEQALDYTEVYRLHRAANSHNVSTCESVASSAVGIALDMGIKLIISITETGSSTKLLAKYRPEANILAVTSSKSTARQLSVSRGVTALLLETMPG------IDDLTFLGIAHAQDRGLILKGEMIILVNGLDDNISASNIVKVIEV 483
750 0.000e+00UniRef50_A0A1W9VLF1 Pyruvate kinase n=1 Tax=Anaerolineaceae bacterium 4572_5.2 TaxID=1971725 RepID=A0A1W9VLF1_9CHLR  ali  34  13......................IVCTIGPASQS--QVEQMMLNGMNIARINFAHGNFEAHRQTIAKVRA-AAAATNRLIAIFGDLPGPKMRIGKLE-EEPLFLERGQSFILQT---QTITGNQYRASMDFEGLPKAVKPGDSIFMNDGYIQL-MVERVEGQKVHCTVKTGGELRSHKGVNFPGIDLGLSAFTPQDRKLLAFAAEEEIDGVSQSFVQNAADIIAVREAAAELDYDPFIIAKIERSGALQHIEEILDAADGLMVARGDLGVEIPIEDIPAAQKQLIRQANLAAKPVITATQMLESMTRNRRPTRAEVTDVANAILDGSDAIMLSGETAIGDYPAETVAVMARIAQRTEETCTAEFGISDLLKLQQDRGDISDLVSSNIFLMAKTLNPALIFIPSLGGATARRVTRFRLSQWIVAPSRKKSACQQLQFSYGVYPVHIASKKVFAKLS---ERRKVARKWLKENGEI--GDLVLLIEG................ 463
751 0.000e+00UniRef50_A0A1F7AGI5 Pyruvate kinase (Fragment) n=2 Tax=unclassified Candidatus Peregrinibacteria TaxID=1801912 RepID=A0A1F7AGI5_9BACT  ali  36  1.................MRHTKILATLGPATEEKSEIRALVQAGMDIVRLNFSHGTFDQFKKIVKNIRAVEKE-TGKTVAILQDLQGPKIRLGDLPEG-QISVSRGDIVTFTAARSAVLNKEKNTIPLPYPVLPKVLKKGHALLIEDGLIRTKILSI-KGRYIRAQVLVGGILKSKKGVNIPDSRLPSSALSEKDKKDLAFGVKLGVDAIAVSFVETAKDMERVRKEVARYSRPVSLIAKVERPKALNNIEEIIRASDGIMVARGDLGIEIPAEQVPIEQKRIIALCRRAGVPVIIATQILQSMEQNPLATRAEISDAANAIFEHADAFMLSNETAVGKYPVRAVQTLAKVAAATEEAIFKNQELFPIPASTNPELIEDETLALNACMVADQVDAEAVVVLTRKGYTAAAIVKHRPKNRILVVTDSIYTARNLHFFWGIHDVVLHKGPLRS---------EESLTALKKKNLLKAGSTIVLV.................. 457
752 0.000e+00UniRef50_A0A136M2C1 Pyruvate kinase n=1 Tax=Omnitrophica bacterium OLB16 TaxID=1617433 RepID=A0A136M2C1_9BACT  ali  30  4............NQQDKFLLSKILATLGPASSDKSTILRLAQAGAHAFRINFSHGTLEQHEKTYRLIRECAEEL-GMPLGILGDLCGPKIRVNNLPPEG-IQLKEGQILSFTTGEGLACCGSDICLTSNFSEWINEITEGEHALLDDGKIRLRCLGVTSDGLVRFEVEHGGKLTQGKGINLPETQLSLPALTDHDYQCVRFALQHDFDFLALSFVKDPEDTQALRRFIRREDPDIPIISKIERPQALDKLESIIQVSDGIMVARGDLGVEIDLARVPVIQKHILKLCKEFGKTAIVATQMLESMIQSPVPTRAEVSDVANAIFDGADAVMLSGETAVGQWPVEAVQVMSRIARRANEYQRSLPLSLNLPQKQIEARFGSAALAHGVCTVAADLDARFVILWCNHEKSAYDLSSYHLSRPVLAYSDQDSILQRLVLSYGLQPIHCEQPTG------IGGFIRFVENDLNQKGYIRQGEPLVFILGYPITQ-----VKVPTV 486
753 0.000e+00UniRef50_A0A1F7BRZ5 Pyruvate kinase n=2 Tax=unclassified Candidatus Peribacteria TaxID=1803395 RepID=A0A1F7BRZ5_9BACT  ali  35  1.................MRFTKIIATIGPASNSLEAITQFSKLGVNICRLNFSHGDYKNHKKTIEIIRTINRK--GGALAIMIDTKGPEVRTGDSVQ--AIKIRKGDRVIFTSKPTGKEK--LKTVTVDYDKFADDVQSARCILIDNGSIEFRLDKIEKNGSVIAVALEDGSIGSRRHVNLPGAHISLPSFTPKDLADIKFGIEQNADFFATSFVRSAKDIAELRNILKKNNSTGEIIAKIETPQAVEDIDDIIDAADGIMVARGDLGAEVPFEDVPRLQEMIVAKCRVRGKPVIVATHMLESMILSPMPTRAEVTDIAYAAKLQADATMLSGETAGGMYPMKAVAAMDKILRASERVEPDFEHLFHHFHSPAGLNDIHHEQALAACILAARLSADAILVITRTGGTAMAVSNCRPLIPIHAFTDTETRERQMMMLWGVIPHHIP------FSLDREQTLLTALDLARKEKFLKKDQRIVVVSDIQTDTRSVMTIQIRTI 474
754 0.000e+00UniRef50_A0A0G0S166 Pyruvate kinase n=1 Tax=Candidatus Moranbacteria bacterium GW2011_GWA2_39_41 TaxID=1618695 RepID=A0A0G0S166_9BACT  ali  38  1.................MKKTRIVATIGPASDSKENMKKIVEAGVNVFRLNFSHGTHESHKKIIDLAKELRKEIK-RPLGILADLQGPRIRVG---NAEPFEIAKGEVISVS----DQKTTDEKELIIDSVRVASALQVGERIMIEDGVMRLKVVEKLEN-SVKAEVLNGGTIKPRKGINLPDTKLHFGAVTEKDQCDLEFALGEEVDFIALSFVSNAQEVLEIKKILGRKDSLPQIIVKVERKEAIDNIDEIIAATDVVMVARGDLGIELAESKVILYQKEIIAKCLTAAKTVIVATQMLDSMISNPIPTRAEVSDVTNAVIDHTDAVMLSGESANGKYPIEAVETMTQIITDTEESPYDDINDHFQDNAV---HSDYASIMHSAHEMAMNAKAKAIVLFSESGVSARMMAHHRPEQMMLVGTHNPKTYNQMAIVWGARAYLFE-------TQDREELVTTMFELNKAAGRLVSGDKVVVILGRVPG............ 456
755 0.000e+00UniRef50_A0A2E3G6W1 Pyruvate kinase n=5 Tax=Bacteria TaxID=2 RepID=A0A2E3G6W1_9RICK  ali  34  9..................RKTKIIATYGPACEPVGSISKLIQSGADLIRLNASHGDKKTLSNVVKRIR-AAETKQKHRMGVFLDLQGPKIRVGKFKEGSA-TLKDNSIVEIYTKKII---GTATQFQVDYPHFLKDVQVGDSLFINDGKIKGVIESVTK-SVARCRITTGGVISNHKGVNLPSTRLSTAAFTEKDKTDAITAINIGCDYVALSFVSSAYDLIEFRKFLNEKGEKIKIIAKIERQQAIDNLVEIIKHADAVMVARGDLGVEIGIERVPRIQKQIIQLCNKFIKPVIVATQMLESMIESKTATRAEVSDIANAIYDHCDAVMLSAETAVGVDPAHVIKVMAEICEETDNHLNDMRRSQTTRKKIFEYDSTAISFCRAADQIAEENNAAAIIAFTSSGNTPLIASKLNSLFPVLAPTDSVHVCNRSTLYRGVTPMMMPKKFKDIYRWT--DMITLAVKEAKLLGILKKGDTIVVTAGIPIGSNGINSIRILTV 486
756 0.000e+00UniRef50_UPI0006B60EF8 pyruvate kinase n=2 Tax=Marinagarivorans algicola TaxID=1513270 RepID=UPI0006B60EF8  ali  37  3..................KKTKIVATVSDLKGDVNFIGELAKRGVNVIRLNTAHQTPEDTRKVIENVRAVSEKL-----AVLVDTKGPEMRT-NLKIEEDLSIQTGQKVTFRSDG-LDVATTKEAVQVNYLGFVNDVPVGAHILIDDGLLELVVDSKDS-EALYTTALNNGKIKKKKSVNVPGVAIRLPSVTDRDKTFIEMAIEAGVDFIAHSFVRNKQDVLDVQNILDAKKSPIKIIAKIENREGVENLDEILEVVYGVMVARGDLGIEIPGEEVPLVQKSMIRKCIEARVPVITATQMLESMIQNPRPTRAEISDVANAVLDGTDALMLSGESAYGDYPFEAVETMARIATHVEEQTAYGINLE----GKADKGNLQEYICQQVAKSARDLNVDAIVVPTSTGSTARQIASHRPSAPLYAACYKPEALRLLSLSYGVESYLIEGAVR-------DTVVKNALTPLIESQAL-TGESLVVVAKSAPGSGETNRMEINTV 466
757 0.000e+00UniRef50_J3L2K1 Pyruvate kinase n=16 Tax=Mesangiospermae TaxID=1437183 RepID=J3L2K1_ORYBR  ali  32  1...................................MIWKLAEAGMNVARLNMSHGDHASHQKVIDLVKEYNAQTKDNVIAIMLDTKGPEVRSGDLPQ--PIMLEPGQDFTFTIKRGV---GTETCVSVNYDDFVNDVEVGDMLLVDGGMMSLLVKSKTED-SVKCEVIDGGELKSRRHLNVRGKSATLPSITDKDWDDIKFGVDNQVDYYAVSFVKDAQVVHELKDYLRSSNADIHVIVKIESADSIPNLHSIITASDGAMVARGDLGAELPIEEVPLLQEEIIRTCRSMGKAVIVATNMLESMIVHPTPTRAEVSDIAIAVREGSDAIMLSGETAHGKFPLKAVKVMHTVALRTEATISGGETPTNLGQVFKNHMS--EMFAYHSTMMSNTLGTS-IVVFTRTGFMAILLSHYRPSGTIFAFTDQERVRQRLALYQGVCPVQME------FSDDAEKTFGDALSYLLKHGMVKEGEEVALVQSGRWRSQSTHNIQVRKV 453
758 0.000e+00UniRef50_A0A2H0SF47 Pyruvate kinase n=4 Tax=unclassified Bacteria TaxID=2323 RepID=A0A2H0SF47_9BACT  ali  36  25.................LKNTKIICTIGPATESIRKLRHLIKAGMNCARLNFSHGTYEHHAKLIRNVRAVSEKMDE-PIAIIQDLQGPRIRIGELPEGEEVVLAAGSLFWIRTEKSDPAAGTQIILPTQ-ENLGRIVKKGEVILIKDGLVRLRAISVR-GACVKARVEQGGVITSNRGINLPESKITNVVITKKDKEDLKFGLKQKVDWIALSFVRDKSDVEHLRGLLKGKSYQPKIIAKIERKEAVENFDAILAASDAIMVARGDLGIELPAEEIPLLQKEFIEKCLKASKPVIVATQMLESMTTNSRPTRAEVSDVANAVIDHTDAVMLSSETSTGKYPIATCQMMRNIIIETEESPYD----DDVKTRGTNKSIVPNIIAHTAEDIVGNDHIRAIVVMSSSGKSAQLIASERPSVPVIALTQNDVSRKQMALIWGVRPFIMKRQR------NVDDLIQSTVKLVKRELKVKKGDKIIIASGHPTGPGSLNLLKIHTV 554
759 0.000e+00UniRef50_A0A1G2HMJ7 Pyruvate kinase n=2 Tax=Candidatus Staskawiczbacteria TaxID=1817916 RepID=A0A1G2HMJ7_9BACT  ali  34  5..................KKTKIIATIGPSSEKKEILEKIILAGADCIRLNFSHGNYEWHQSVISNVRSLEKKLK-KNIAIIADIQGPKIRVGIMPKEGA-NIQQGEKIVFNCDLKEY-KGNE--IPLPSQMFKGGVKEGDVVFLDDGTLSVKITKKL-GSKFEASVLKGGFLFSNKGINVPSIKITGSVFSDKDKSDVKFAVSHGADYLALSFLREGKDIKEIRSLI--NNSQIKIIAKIERPEALANLDGIIEEADVVMVARGDLGIETPMWELPIRQKEIITKVREKMKQVIVATQMLDSMIRNPLPTRAEVSDVANAVYDSTDAVMLSGESASGKNPVEAVEMMRKILEATDSNQTYSRVPEEMYDEPYIY------LSKSAADVSSELKTKAIFVKTQSGRSAKSISSFRPQNTVVAITQDEMVSRQLSLVWGVLPILIGKK----SIKKIDDFVLPAVSILKKENLIKSGDSIVCVYDHKFESPSANSISIKTV 471
760 0.000e+00UniRef50_A0A2E3TNU1 Pyruvate kinase n=6 Tax=root TaxID=1 RepID=A0A2E3TNU1_9GAMM  ali  32  4..................RRTKILATLGPSTDNPEVLKGILDAGVNVVRINFSHNNEKEHLERIAQIRKYEKENDIF-IGILMDLQGPKIRISAFKGGK-IELNNGDHFALDAELD-DSEGNQDSVGIAYKELPNDLNVGNTLLLDDGKIILEVKQI-SGQKIFTEVKQGGILSNNKGINLRGGGLSASALTNKDKKDIITAAKADADYVAISFPINADDVRETKRLLLKAGSNASVIAKIERAESLDVITEIIQESAGIXVARGDLGVEIGDPQLPAQQKRLILLARANDRFVITATQMLESMITSPXPTRAEVFDVANAVLXGTDAVMLSAETAVGAHPVNAVKTMNDVCLEAEKSPTAKVSHHRLHEHFEG---IDETIAMSSMYAANHIGARVVATLTQTGKTALWMSRISSNIAIFAMSDNYKTLKKVTIYRGVYPCYIDKTSADDWNDVNSHVIENLESKAV----VARGDVVIVTKGMHKKSGGTNLMKILRV 477
761 0.000e+00UniRef50_A0A1J4XEQ3 Pyruvate kinase n=5 Tax=Verrucomicrobia TaxID=74201 RepID=A0A1J4XEQ3_9BACT  ali  36  6..................RHTKIIFTIGPATEGIEVITQLINAGADICRLNMAHASHEWTRQTIANIRKAS-EIAGKDIAIMMDIKGPEIRTGDV--DVPYNLSKGDQLDVTAMGNPLDHAPIYATYVNYPNLINDVNEGDALLIDSGHIQLRIMEKQAD-FLRCEVVIPGRLTSRRHVNLPGVYVSLPPLTEKDKGDIAVGIAENIEFFALSFVREAGDIVALRKILQEKDSQAKIIAKLEDQTAITNMEEIIIESDGLMVARGDLGVECPFEQLPIIQRTAVAMSIKNTKPVIVATHMLESMISSPLPTRAEVSDVANAVSEKADAIMLSAETTIGKYPIKCIEVMNSISCAMEEIAVTEYN-KDLELCTPKTK-----ILRSAVVLAQELNRAGIIAFTNTGLLTQVLSSLRPKCPIFAFTENEAVYKQMHLLWGVYPFL------SKFSNNPEITIEEAFKSLKATGLVETGNTMVVVTNIILGPSIRDSIQIRVI 476
762 0.000e+00UniRef50_A0A1H0CUS5 Pyruvate kinase n=1 Tax=Desulfonauticus submarinus TaxID=206665 RepID=A0A1H0CUS5_9DELT  ali  33  2...................RTKIIATLGPASNNVEVLKQFLAQGVRIFRLNFSHGSAKDFAPLVQKIRTLEEDLKE-PITLLQDLCGPKIRIGKLKK-SPLTIHKNSFYFL----GKGEETSENFIPFEDKSLLEHLKPNDIVKISDGGLSFEV-KTNSPTELILEAKDSGIISSGKGITFPGKKLKLSAITEKDKQDLIEGLELGLDAIALSFVQGPEDIAKAKAICDKKGRCVPIIAKLERQAALDRLEDIVSIADGIMVARGDLGLECPLPQLPFIQKKIIRLCRKMGKPVIVATQMLLSMVNNPMPTRAETTDVANAILDSTDCVMLSEETAIGKYPVECITYLKQIAEEAEKNIFKIRKQIDLPANGHSEMF----IAHAACILADKLQAKALLAHTNSGTTARLLSSFRPKEYIYGLCPNPTVSKYMNFFWGVIPTIIDENPKDH--------LQRVELYVENSSLFKSQDVLVITAGHPKKHAPTNLIKV... 464
763 0.000e+00UniRef50_A0A097IU81 Pyruvate kinase n=18 Tax=Rhodophyta TaxID=2763 RepID=A0A097IU81_9FLOR  ali  34  88..................RMSKIVCTLGPKTCDVQSIEKLAETGMDIVRLNMSHGTHEWHENVIKNVREINSKGTF-NLAILLDTKGPEVRSGDLK--TPLKVKRGQQFTWTIRKDV-ENFDTNMVDVSYDDFINDVKVGDMLLVDGGMCSFLVTD-MTDTDVISECIDGGTLTSRRHLNVRGKSASLPAITQKDWEDIDFGIKMNVDFYALSFVKHENDVSRLIEYLRNKNCKAYVLSKIESADAVHRLRPILEASDGAMVARGDLGAEIPIEDVPLIQDEIIGINREIQKPTIVATHMLESMITYPTPTRAEVADITEAIRQGTDATMLSGETANGSFPIKALTVMATVAESVDNALSNTDLFSPLNSDAYSDVDPRFHLAFNASTLASRLNVATIVVFTRTGTYAKLISATRPRCPIVAFTPDSDLVRRLTLLWGIKPYQME------LLDDPEETISNAIKLLKEKGLVCSGDNIVISSDMLSGLETVDTIQVRRV 562
764 0.000e+00UniRef50_A0A2N6N6A2 Pyruvate kinase n=31 Tax=root TaxID=1 RepID=A0A2N6N6A2_9COXI  ali  35  9.................LRRTKIIATLGPSTDDPSILEDIINEGVDVVRLNFSHDSHERHKKRIEMVREAAKKQE-RVIGILADLQGPKIRISSFKLGKIKLKKGDQ-FILDAD-LPPSEGMEEGVGIDYKNLPQDVRANDLLLLDDGRLTLMVQDVNENK-IICRVIVGGELSNYKGINRLGGGLSAESMTKKDIEDLKFVVNLNVDYIAISFPRDTEDILKAKDLIQGYKGKAGVIAKIERTEAVKNIDGIIEASDGIMVARGDLAVEIGDAQVPLVQKDIIHRVRSLDKPVIIATQMMESMIHASVPTRAEVSDVANAVLDNTDAVMLSAETAVGHYPVLAVGAMARTCVASE---LQPRSYISRHRVECCFKRIDEAVAMATMYTANHLDIQAIVALTESGITPLWMSRIRTAIPIYGLSRFDKTLGRMTLYRGVYPIKFDPTQHSR-----EEVNIKAIEVMEKQGLLKQGDLVILTKGDHMGVGGSNAMKILTV 480
765 0.000e+00UniRef50_A0A2I0P1F4 Pyruvate kinase n=3 Tax=Methanomicrobiales TaxID=2191 RepID=A0A2I0P1F4_9EURY  ali  34  24............TPEPGVRLTRIIATIGPSCADIGTIHDMIRAGMDIARLNLSHGTFEEHQEVFLRIRLAAREI-GRPVAIMVDIPGPKLRIRSLRND--LTFQQDEQVILASDPNPGSIVVGPSAYIP------DVQPGDIILIGDGAVTLTVTK--GGDIIRATVKAGGTIRPGAGVVIPGRRPKVPYENDELVRNLSFAASMKPDFIALSFVGSADHIHSVRTKLQKNGIRIPIIAKIETRLAVDRFEEIMAAADGIMVARGDLGVELPIACVPHVQKDIIRRCNKAGIPVITATEMLESMVEHTRPTRAEVTDVANAIADGTDATMLSAETSIGIHPQLAIITMAQIACETEKHLPYRQILSE--RAGWHEDNPEGIISYSACYLANELASRAIVAFTRSGVTADRVSRCRPGTPILAITPDESVGRRLLLRWGVIPCIHEPIHT------VDELFRISLDLTKAMGITCSGDRLVIIAGNFAGQGTTNMIKVQIV 493
766 0.000e+00UniRef50_A0A259DSG4 Pyruvate kinase (Fragment) n=1 Tax=Thiotrichales bacterium 17-46-47 TaxID=1970602 RepID=A0A259DSG4_9GAMM  ali  32  10..................RRTKIVATLGPATDKPGVIDSMIQAGLDVVRINFSHGSADEHIERARFVRERAKAL-GSEVGVLVDLQGPKIRIARFSEGY-VHLDEGADFALD-NNIGRLEGNINGVGLDYKTLPHEVKPGNRLLLDDGRVVLEVKQVVGER-VECTVIVGGKLSNNKGINLLGGGLSAAAITEKDKEDIVSAAKIQADYLAFSFPRSADDVNECRRLASEAGLKCCIVSKIERAEAVQDLEEIILASDAVMIARGDLGVEVGDALLPSLQKKIIKLARQHNRVTITATQMMETMIDNPIPTRAEVFDVANAVIDGTDAVMLSGETATGKHPHVVIEAMSRICYEAEK---QRETRVSTHRIDQVFQATDESIAMGAMYIANHFNIRAIAALTESGSTALLMSRISSGIPIYAITPHEKTRQKVTLYRGVYPMAFNYEGM-----DNDEVVPNMIEELKRSGQVKDGDKVLVTRGKHRGMGGTNVLLILR. 481
767 0.000e+00UniRef50_A0A2H6H7Z1 Pyruvate kinase n=2 Tax=Bacteria TaxID=2 RepID=A0A2H6H7Z1_9BACT  ali  34  28..................RHTKIVVTLGPAVATAEAIDGLVAAGMDVARLNFSHGDHDTHRKLATFVREAA-TRQKRAVAILQDIQGPKIRVGTFPGG-GIRLKRGDQVSLVAG---MGLGDAERIEIGYPRLVSDVGVGSEVVLADGLVRMKVTEQTRDRLI-AEVIEGGLVGDHRGAAFPKANLRVSAVTEKDKVDLAFGRELEVDFVAASFVRSAADVERVRQLSG-----VPVIAKVELAVAFENLDAILSVADGVMVARGDLGVEIPLERLPSVQQDILRRTNAAGLVSVTATEMLESMIHSTRPTRAEVTDVATAVMEGTDAVMLSGETAIGDYPIETVAMMDRILVEADRPRSDHQSIGFL----PGQAGYASAMARAAVEAATDLGLGTIVAFTESGSTARLLSKYRPCAAIMAFSPVERTRRRMAIYRGVTPVAFER------LDSTDAMIEFADRYLADHGVCSAGEGVVIVAGTPPNSASTNLMKLQTI 489
768 0.000e+00UniRef50_Q56301 Pyruvate kinase n=144 Tax=root TaxID=1 RepID=KPYK_THELN  ali  37  7...................KTKIIATIGPASKQKETIKKMIKAGMSVARINFSHGTXXXXXXXXXXX-XXXXXXXXXXVAILGDLPGLKMRVGKIKGD-SVTLRKGDKVVLTTRD---IEGDETTIPVEFKDLPKLVSKGDTIYLSDGYIMLRVEEVRENEVEC-VVVNGGILFSHKGINIPKANLPIEAITPRDFEIIEFAIEHGVDAIGLSFVGSVYDVLKVKSFLEKKSADLFVIAKIERPDAVRNFDEILNAADGIMIARGDLGVEMPIEKLPIMQKQLIKKTNLAAKPVITATQMLVSMTTERIPKRAEVTDVANAILDGTDAVMLSEETAIGKYPVESVEMMAKIAKTTEEYRESLGYLRAWIDSLPKRSTIKEAITRSVIDALCAIDIKYILTPTRTGLTPRLISRFKPKQWILAFSSSERVCNNLAFSYGVYPFCMDE---NFNEKDI-------IMLVKGLGIVKEDDTVLLTEGRPIGKTGTNTMRIFQI 474
769 0.000e+00UniRef50_A0A183AWP4 Pyruvate kinase n=1 Tax=Echinostoma caproni TaxID=27848 RepID=A0A183AWP4_9TREM  ali  33  41.THLDHISQLDIDSAAYVRQVNVVCTLGELWNSDVQIRDMIRGGMNILRMNLSMGTHEFFADAIRRVRAIEESLDHNPIGVALDISAPPVRTGLVNNDVDIVLNDGQTVQLTTNDEYQNKITDGVIWIDYPTVLHCLSPGDRVHLDDGMLSLIVKEVRSDTA-DCVVERGGELGSWKRVELPSEKIYPEDFEHKYKVDLVFASQCKVDYVFTGYASTVSKLMYAKKIL---GPEIKLFAKVENREAMHNLKELMSIADGIIIGRNGLGLCYPHEKIFQIQKQLIAKCNILGKPVFVIAQLLESMRFKPRPTRAEVTDVANAVLDGADGLILTVETSRGLYPRQALRVLHKTCREAESVVYHEKFCYDLKFSRDSPMEPTYFAALAAVEASNACNASAIIVITASGRSATAIASFRPFCPVIAIVRRPEVARHCHSFRGIHPFVLTDEQLADWPVDMDSRLNKAVDFGRGRGFIAGGDNVVIVTRWEAGVGVTNTVRVFEV 576
770 0.000e+00UniRef50_UPI000DEB383F pyruvate kinase n=1 Tax=Arenicella xantha TaxID=644221 RepID=UPI000DEB383F  ali  34  9................NLNRTKIIATIGPSSSSADVLEELIKNGCSVFRINFSHGSHESHGESIANIRKVAEKL-NQNVAILGDLQGPKIRIGAIQGG-SFKLTQGQELLLDSSIDDEAGSPDGVSYV-CATLAESCGPGRVLMLDDGRVQLE-VQSVAGQAIHTKVIAGTKLSSRKGLNLKGGGLAEDALTPKDMRDMAFAAKQNLEYICVSFPASAQDMLDARTKLDELDCPSKLIAKLERAEVVASIDDMINSCDGVMVARGDLAVEVGFEAVTSYQKQIIARSRTLNKPVIVATQMMESMIDSPVPTRAEVSDVANAVFDYADAVMLSAETAVGDYPIEVIKTMYDVITATEK---HTLTQVSKHRVEIEFQYVDESIAMASMYLANHFKAKAIVCLTESGSTALWMSRIKTHLPLVAMSPRQDTLNRVALYKGVRPAHLPRESESNT------RLEDVIQYVRKAVDLEKGDYVAITYGDVVGVGHTNTLKLLQV 484
771 0.000e+00UniRef50_A0A0A9ZC18 Pyruvate kinase n=5 Tax=Panheteroptera TaxID=33351 RepID=A0A0A9ZC18_LYGHE  ali  31  47...LEHNANLDIESPKPALLSKIMCTLGESCLDPQVFGRMMKNGMAIVRVDMSIGDQNNHLEQIRKAREAVMEYSAAPVAIAAELKGPQILTGGLEPGIDVVLQEGDTINLTTHPGFDVKGNKSCLYVDHKELPYVLKPKDKVLLDYGRITLSVRGCY-DHEIVCEVVTGGALQGYADVTVIDVPLNIPYLTNKDKKDIEVLTAEQVDIIIVPHVEDRKCLEEVRKLIGVRNTGIQLMAKIDSKLGYKNFDAILESADGVIIDRGKISVEVSTEKVMQAQKTMVAKANKAGKPVFGACEYLNSMIVRNCPTFAEATDAINAIVEGIDGIVLKEETARGEYPALAVRTLATLAREAEGQIWQHEIWKSLNEAATPPIDPAHAVVISAIEAANKAHATAIILATTSGTSARYLAKYRPRCPVIAITRYGSVARKLHMFRAVWPLHYIVAPNPNWCLDVDLRLQFGINAGKLEGIIKPGDPLVLVSGWRQGAGFTNNIRVV.. 547
772 0.000e+00UniRef50_A0A1Y0H7U3 Pyruvate kinase n=1 Tax=Armatimonadetes bacterium Uphvl-Ar2 TaxID=2004468 RepID=A0A1Y0H7U3_9BACT  ali  37  3..................RRTKIVATLGPATQNAATVRALIKAGVNVVRLNCSHGDWESKAEAVEWVREANPAVA--PVAVMADLQGPKHRLEQLAAS-PLMVKAGQML------RMGPDGQGYELPIDEPDVLNSLAVGDKILVGDGDVALR-VRAAEGQVFEVEVLTSGAIKSRQGVTVAGKSFQGSCLTDKDKYDVFEAAKMGVDYIALSYVKSASDMLELRRLVDQYDPGIRLVAKIETKEALRDIDQILQASDVVMVARGDLGLQLPIEDVPVAQKRIIARANAMGKPVITATQMLESMIVNARPTRAEATDVANAILDGTDAVMLSGETAAGQYPVEAVKTMARIAEKAES----LGQDEAPRPAPVKNQDCTEAVAHAAVEVAESLRARAIVTSSTSGATPRWVRKFRPDVPILCATWDERVQRQLAMVGGVMAALIPSP------ETTDEAIGLSIEAFLKAKELKMGDQVVLTCGVPPGAGNTNLILVRTV 465
773 0.000e+00UniRef50_L1JZX9 Pyruvate kinase n=1 Tax=Guillardia theta CCMP2712 TaxID=905079 RepID=L1JZX9_GUITH  ali  37 1179........GLDLVCEPSVRKTKIVCTMGPACWSEEVIGKLLDAGLNIARFNFSHGSHEGHLEVLERFRGV-CASKGSHAAVLLDTKGPEIRTAMLREHKPILLTKGQEIIV------EAVGDEYSSWEGYKD-----ESETRIGLSYAKL---CQSIRSERGAQGVVLNEKELGERRLQPAGRGRVDIPVLTAKDIDDVQFCAKHKMDFVAASFVQTGEDVKLIRRTLDEAGGDVKIISKIENEAGLENIDDIIRETDGVMVARGDLGMEIPSEKVALAQKMIITKCNIAGKFVITATQMLESMVKNPLPTRAEMTDVANAVFDGTDCVMLSGETANGSFPDTAVETMASIVANAEIGVNYPQVFSSLRDFTPKPMGFMESMLCCAAKNAVDCYAGLIVLFSKTGRAARLVSKYHPFVPVVVISDNERVTKQLNASFSLLPYPVTEIPQEP--DQISRMMLDVIDWAVDKQICLSDSKVIIVKGAH.............. 1643
774 0.000e+00UniRef50_R5V555 Pyruvate kinase n=1 Tax=Firmicutes bacterium CAG:631 TaxID=1262996 RepID=R5V555_9FIRM  ali  34  2.................LNKTKIVCTIGSQSEPESVMEQMLLEGMNVVRLNFAHGNLTTQGRFAVTAKKLA-LIHGKPLSIMIDTRGPKVRTHTFKDG-NASIAKGCKVIIHTTPIVG-SCDE--FSVTYEGLFDDVQADDQILVDDGNLILRVIEKKSNRSLVCESINSATIKDESSVNVPNAKINVPYLSQNDLVRVDFAIAENLDYIGAAFVRNGQDVLDLKNYIASKNGHQKVVAKIENLQAIEHLDEIIAAADGIVIARGDLSIEVPVEDIPILQKRIVKKCNDAGKFVIVATQILSSMSRNKKPSRAEVSDVANAILDGVDAIMLSNVSATGKYPVEAVSTLSKICSRTECEIFYKGKIQKAYNSSEKTLN--DAVALSVADTALLVDAKLIVAFTESGTTAKRISKFRPCCPIAAVTSSEEIRLSLTLNWGVYPVVSNQPTSE------LDYVNKACEIATYYG-VKEGENIIITGG--NGVGNTNFMKVVK. 468
775 0.000e+00UniRef50_D5BYP4 Pyruvate kinase n=8 Tax=Bacteria TaxID=2 RepID=D5BYP4_NITHN  ali  36  24..................RACRIICTIGPSSQSPAILEKMLLSGMNVARLNFSHGSQESHGTIVHEIRKTAQRLM-KPIAILQDLQGHKVRVGSIQHSPSLCLNEDQEILL----GHGETVSNKRIGIDYQGITDYVAPGQHIFLDDGSIELEVLSTRGDD-LHCRVKLGGELSSRKGVIFPDSHLSFPLLNEKDENDAHFGVFLNVDMVAMSFVRSATEIIEMRLRLAAWGKDSFIVAKIEDRKGIDNLDEILHVADAVLIARGDLGVTLPREKVPGIQKTIIQKTNAFGVPVITATQMLESMIYHDKPTRAEVNDVYSAVMGGSDAVMLSGETASGRYPLHAVREMDRICREAEKELRSFKGEIPVRGRR----DMHDKMAASAVNLARNTKARCILAFSLSGATLKALSTARSNVPVYGVVVEERVLRQLLLHWG------HSLITMPHEEKLEDLIGPVLKQLQEQGIVRTNDRIVVMA................. 473
776 0.000e+00UniRef50_UPI00083C2995 pyruvate kinase PKM-like isoform X1 n=2 Tax=Nicrophorus vespilloides TaxID=110193 RepID=UPI00083C2995  ali  34  39..QLSYQSKLDFESPARKRLTSIVCSIGPSSSSVDVLEDLITAGMSIARIKTPFFTQIEAIQMVANIRLAADNVSRKPVAIGFDLRGPEIRTGVLKHDGSVQLHQGNETVITCDPSYEEHVTEDMIYVDYQKLHEVVEPGDRFYLDNH-VTLSALEIVG-SFIRCIIETAGRIGDRVSVSMDNSILDLPSISE---VEVERAKELDVDIIFVSSVKSKEVIEEVRKYLGDDGKHVVVVAKIENELGVKNIESIAKEADGILLSRNNLANEIAVEKTFLVQKMIAAVCNKLGKPMICAPQMLDSMVSALHPKRCEVTDIANAILDGVDCLMLSRETACGDNPVECVHTLSGICKEAEAAVFHRKLFEALTQEVPIFMEPIYSLSIGVVEASVKSSAAAIIVLTTSGRTAKIIAKYRPRCPIIAVTRHSRVSRQLRMYRAVEPIHFIKKPLSDWTQDVRRRLQFAITFGKYLGFIRAADTIVILTGNRPGTGFTNTMSV... 536
777 0.000e+00UniRef50_A0A2E4F8P4 Pyruvate kinase n=1 Tax=Deltaproteobacteria bacterium TaxID=2026735 RepID=A0A2E4F8P4_9DELT  ali  35  4...............PRLARTKIVVTLGPATQSPEMIEALIEEGVNVFRLNMSHLDHATAGAMIERIRAASDR-----VAIMADLQGPKMRVTDV--DEVFELTKGERVIVRAGEQL---TTREALYVPAGDLVSILEPGQRVLIDDGRVRLRVTETRAGE-FDAEVIAGGPIKSRKGIACPDVRYPESYLNAGDRADTAFAVERGVDFIAASYVSDVDDVTTLREAMGEEGLAIGIIAKIESRLGVENIDAILAHADGMMVARGDLGVELPPEEVPLIQKRLIKRAKLVAKPVIVATQMLESMISSPVPSRAETSDVANAILDGTDAMMLSAETSVGAFPLEAVRTLIRVSEHVERETAAPPEHLFNRPA----HGTVEFICRAAAKAASELNVKAIVAFTTTGSTASNMAAYEPRVPVLATTPSAIVVRKLGLQYGVHAVQAEHIGRY------DIMLYRNVQKLTRAGILEPSDSIVVIGGVPVGPGSTNMLQVGTV 469
778 0.000e+00UniRef50_A0A0H1BH75 Pyruvate kinase n=1 Tax=Emmonsia parva UAMH 139 TaxID=1246674 RepID=A0A0H1BH75_9EURO  ali  63  12.SKLEWMSKLNIANYANFRRTSIICTIGPKTNSTEKINILRKAGLNVVRMNFSHGDYDYHQSVIDNARRAEKVQEGRPLAIALDTKGPEIRTGKTVDGKDIKISEGTELIITSHDDYAEKSDINYLYVDYKNITKVISKGKLIYVDDGILSFKVLEIIDDSSLRARCLNNGVISSKKGVNLPGTDIDLPALSEKDKEDLRFGVKNKVDMIFASFIRRASDIRDIRAVLG--------------------------------------------EEVFIAQKMMIAKCNIKGKPVICATQMLESMTYNPRPTRAEVSDVANAVQDGADCVMLSGETAKGDYPKEAVTMMHETCLIAEVAIPYVNVFDELRNLAPRPMDTVESIAMAAVSASLELNAGAILVLTT................................................................................................. 379
779 0.000e+00UniRef50_UPI000C201B37 pyruvate kinase-like n=1 Tax=Onthophagus taurus TaxID=166361 RepID=UPI000C201B37  ali  35  39..HIEHLCRLNVDSLPTWRLCGIMCSIGPSCNDPEVLLNMMKAGMTMAYIKMAHTTLDGVKDTLKNIKIAQNRYCKVSIGIGIEIKGPEIRTGIIEDPKDIELKEGDETSLTTDPMYEQFVSKDMIYVNYDKLTQVVEPGDKILISDGSVTLSAIEIVG-SIIRCLIENAGTIANNASVSL-EAAIDLPLLSEEDEEVLQFAAKERISYIFIPYAERADILTQVRNTLGDNGKATMIISKIENLAGIYNIDELIPASDGVLVSRCALGREIPFEKMILVQKMIVGKCNKNGLPVIIAPHMLQSMVKQPTPTNAELSDITSCIADGVDAFALTKETAIGPYPVESVDKLNVICRHAEPLVYQKQLFGDL-TKTVSPIEPIYAIAIAAVEASLKVNAAGIVVTSVTGRSAKLISRFRPRCPIITVTRHGHVARFLNLWRGVFPIQYIKRYDEDWCKDIERRVQYGLTYGKLAGYVRTGDAVVLITGSRTGAGFTNSLKIV.. 542
780 0.000e+00UniRef50_A0A1W4XFM4 Pyruvate kinase n=1 Tax=Agrilus planipennis TaxID=224129 RepID=A0A1W4XFM4_AGRPL  ali  32  44.NKLEHLCKLSLDSDPRCRMTKIMCTIGPSCFDMKTMINLMKAGVNIFRIKMSHTTVEFAQELVQNIRTARDKYSQQNIAICFDLEGPGFYTGNLEDSTSYQLELREGFVLTGNKMFKEFVNEDVIYVSCDLVQEVVKPGDKVYLEHGAIVLEVLEIDRGE-VKCIVRQGGYLTSKSTVDIPGIPIMTDTVTEKDVLTLQLAVQLKIDSVVLSEVRNSQVIIDVRTLLADGGVGMVLIPKIDFAANIDEFDKILELSDGIYFSRERLRIEITSEKLTIVQKMVIAKCNKAGKPICCASSLLESMITLSRPLKAELTDVANAVMDGADCLVLSRETSIGDSPTSAVKILSGLALEAESAVYAREVFQNLISNYETPVEPEKALAFSAINLSMRCYAAAIIVCTVSGKSARLLSRYRPRCPIIAVTRYANVAQRLNMWRGVLPFLYFKRPICNWKKDLDTRIQVGMTYAKLNGIVRAGDAVVVVKALRLGSGFTNSMQIV.. 549
781 0.000e+00UniRef50_A0A2E1BIT3 Pyruvate kinase n=11 Tax=Chloroflexi TaxID=200795 RepID=A0A2E1BIT3_9CHLR  ali  34  7..............KSNLKKTKIVCTIGPSSDSVEIIEGLIDAGMNVARMNLSHGNEKDHKKIISNLRKAAKNR-NIYLPILADLPGPKYRVGEINNGI-MEVKENQVILFECDNEKLESEEINIWP---SGLNKDVEVGAILMIDDGAVELEVTAINQTK-IETIVKLSGKISSNKAVVARGFPSMLDYFTEETESSINFVISNDIDYIGLSYVRNADDIKRVKTKLGD--KKLRIISKIELQKALDNLNEIIDNSDVVMVARGDLGVHLPISKVPSAQKYIINLANKKGKEVITATQMLESMTENPQPTRAESTDVHNAVLDGTDAIMLSGETSIGSYPVRAVEFMREISGIAEKDINHNYIRKKLENINSKDVNVDELIAHGAASIAEQLKSKLIVAFTESGSTAARVASYRPSQSVIALSPDSSAEINLGLRWGVNTI------NVSNFDQIEEMFQYANNIVKEHNLASIGDTIVVVAGLPIGVGNTNLIRVINI 481
782 0.000e+00UniRef50_A0A2E3AYJ1 Pyruvate kinase n=1 Tax=Dehalococcoidia bacterium TaxID=2026734 RepID=A0A2E3AYJ1_9CHLR  ali  31  21...................KTRIICTIGPSSSSKKQIKEMILEGMSVARLNLSHGNAQFHKMCIENILEMSKQL-DAPVGILADVPGPKFRIGKIETDI-LKLTKNDNIIIDLSSENNKNDSSSNLQPSLPGIENEIQIGSELLLDDGSIKIKVSSINKEK-INCIVENSGILKSNKSLVIPGKGSKLNYFTPETKESLEFIANNEIDFVGLSYVRSENDVERVKDFFSNKTNKPKLISKIELPLDLITLEKIIKSSDGVMVARGDLGVQIPISKVPSFQKKIIKLSNKIGKPVITATQMLESMIESPNPTRAEATDIYNAVNDGTDALMLSAETSIGKFPIESLKKMSEIALEAEKDFDHI-NFMENRNNEDLTTLVDEAISYGACKTAHSVQAKLIIAFTESGSTAGRIASFRPEKPILALVANKSVTKKLSINWGVIPLPAPKFFK------VQEMFSAGSKAALETKLAENGDMAVLVVGMPIGVGNTNLMRIMKI 496
783 0.000e+00UniRef50_A0A0F8C589 Pyruvate kinase n=1 Tax=Larimichthys crocea TaxID=215358 RepID=A0A0F8C589_LARCR  ali  44  512.TFLEHLCLLDIDQEPTARNTSIICTIGPASRSIPKLQEMVKAGLNIARLNFSHGSHEYHGETIKNIREAVETITSRPVAIALDTKGPEIRTG-LVKGVNMSLPRMSE---TCGEFWVHTGEIS-------NFEEILAESDGVMVARGDL---GIEIPAEKVFIAQKMMIGR-CNSAG--KPVICATQEILAESDRGDL--GIEIPAEKVFI-----AQKMMIGR--CNSAGKPVICATQ-----------EILAESDGVMVARGDLGIEIPAEKVFIAQKMMIGRCNSAGKPVICATQMLESMVAHPRPTRAEGSDVANAVLDGADCVMLSGETAKGLFPVEAVAMMHSICREAEAAIFHQQLFEELRRLTPLSSDPTEVTAIGAVESSFKCCAGAIIVLTTSGRAAHLLSRYRPRCPIISITRTPQVARQSQLLRGVFPVLFHPLPAPVWADDVDNRVNFGMDIGKARGFFKSGDMVIVVTGWIPGSGHTNIMRAVNV 984
784 0.000e+00UniRef50_A0A0L8GKS8 Pyruvate kinase n=1 Tax=Octopus bimaculoides TaxID=37653 RepID=A0A0L8GKS8_OCTBM  ali  37  18.SFLEHLCSLDIDTPPHM--TSIIATVGPACDDIEILRDMIKAGVNIFRVVMAYGDYSYHSRFIKNIRQVAKELMTSPVGIAIDIAGPEVRLGKLKPKLGREIFFKHRVRISYDTENINNMDDSFLYIDQQKLIDYAKVDNIIVIEDGPLSFMVVDKEQKSTLICEVIEEGLLGNRQTCHMKGMP-DMFELSENDKNDLQFALDEQVDMVFMSLVSDRKVVQLARDFLEKKGKSIKIVSKIENYKGVKNISDIISVSDGIIISRGNLGISIKPEKLFKAQKMITGLANIAGKSVTCASQMLESMTIHPRPTRAEAGDVANSVLDGIDCVMLSSETAKGKYVMQSIKTLVQICGEAEGAMFTYQFMKDLSTITDFRLSKEEATALAAVKGAISCEAKAIVVVTSSGKSAALISRYRPRCIVIAVTKTPITARQLHLYRGVLPFIDQSPVTGLWEKDYNLGIKKAFENAVQRGFLKVKDRVLLVRGWTEGSGSTDTMCVATV 525
785 0.000e+00UniRef50_A0A182EI30 Pyruvate kinase n=2 Tax=Bilateria TaxID=33213 RepID=A0A182EI30_ONCOC  ali  54  12............................................................................................................VIVTTNDAYMSKCSLEMIYVDYKNIIKVIKKGSPIYIDNGLIMLLVKEI-DGESIHCKIENGGLLGSQKGVNLPDALINFPPVSEQDRKDIRFGVEMGIDIIFASFIRNADGIREIREILGEKGKQIKIIAKIENQQGVDNADEIIQEADGIMVARGDLGIEIPAEKVFLAQKMLTAKCNIAGRTVICATQMLESMINKPRPTRAEGSDVANAVLDGADCVMLSDETAKGKYPIEALSTMHQLCKQAEMTIFYTKISEELIRLTPKPTDHAQTIAIAANSAVQSCQAVAVICVTVTG............................................................................................... 307
786 0.000e+00UniRef50_A0A0N4WFS6 Pyruvate kinase n=1 Tax=Haemonchus placei TaxID=6290 RepID=A0A0N4WFS6_HAEPC  ali  50  103......................................................................................................................................EVVKKGSRVYVDDGLISL-VVDDIKDNSISCTIENGGMLGSRKGVNLPGTAVDLPAVSEKDIQDLKFGVEQGVDMIFASFIRNADGVRAIRKVLGEKGKNIKIISKIENQQGLDNSDEIIAESDGVMVARGDLGIEIPTEKVFIAQKMLLAKCNRAGKPCICATQMLESMTKKPRPTRAEAGDVANAVLDGADCVMLSGETAKGDYPLEAVKTMHFICKDAENSTYHAEFLQDLLAESVRPFDMTQSTIIAAVIAAINCHAAAIVLVTSTGRQIVLLRHSLQNCHLLLLSSSKRLPSAKHLQVGVFPVFYSKSRQSNFNTDNENRITHGVEFGKEKGMISKGDTVVAITGWKPGPGFINTVRVIT. 492
787 0.000e+00UniRef50_UPI000C298D07 pyruvate kinase-like n=1 Tax=Piliocolobus tephrosceles TaxID=591936 RepID=UPI000C298D07  ali  47  7..............................................................................................................FVTDYDYLG--DETCIACSYKKLPQSVSKGNIILIADGSVSCKVLETYDDHVI-TEVLNTATIGEKKNMNLPNVKVDLPIISEKDKDDLNFAIPMGCNFIAASFIQSAEDVRTIRNLLGTRGRHIKIIPKIENVEGIINFDKILAESDGIMIARGDLGMEISSEKVFLAQKLMISKCNLQGKPIITATQMLESMTKNPRPTRAEVTDVANAVLDGTDCVMLSGETAGGKFPVEAVTIMSKICMEAEACIDHKLLYQSLVNAIKTPISIQEAVARSAVETAQSIDASVIITLTETGYTPRLIAKYKPRCAIIGITQSDSVIKCLNIHRGVTCV---KVKMISSTDDV---IKHAIEVAKKRNIIKVGDNAICIYGIKEVAGSTNSMKV... 385
788 0.000e+00UniRef50_F7GNF5 Pyruvate kinase n=15 Tax=Amniota TaxID=32524 RepID=F7GNF5_MACMU  ali  45  10....................TAFTQTQHPASRSVEKLKEMIKSGMNVACLNFSHGTHEYHVETIKNVRTVTEIFASRPVALALDTKGPEIRTGLISSTVEVGLKMGATLKIMLDNAYMKKCDENILWLDYKNICKVMEVGSKIYVDDGLISLQVKQKGAD-FLVTEVENGGSLGSKKGVNLPGAAVDLPAVSEEDIQDPKFGVEQDVNMVFTSFIHKASDVHEVRKALGEKGKNIKVISKIENHS---------EASDGIMVASGDLGIEIPAEKVFLAQKMMIGWCSRAGKSVIN-------------------SDVANAVLNAANCIMLSGETAKGDY----LEAGRKQHLIAHEAEAAIYHFD--------PTKAT-TVGANETS--FKCCNGAIIVLTKSGRSAHQVARYRPRAPIIAVTQNPQTAGQAHLHRGIFP-VLCQDPVQEGAKDVDRWVNLAMNVDNAGSFFKKGDVDVAIAGWRPGSGFTNTVRVVSV 454
789 0.000e+00UniRef50_A0A0A9WE97 Pyruvate kinase n=18 Tax=Opisthokonta TaxID=33154 RepID=A0A0A9WE97_LYGHE  ali  58  1.............................................................................................................................................MIYIDDGLLKLQVEDILNSQSVTTIIQNDAVISSQKGVNLPGTAVDLPSLSEKDKKDLRWGVAHHVDFIFASFIRSGEAIREIREQLGAAANRIQIISKIENQQGIENIDSIIQESDGVMVARGDLGIEIPVEKVFIAQKMIIAKCNILGKPVICATQMLESMTTNPRPTRAEVSDVANAVLDGADCVMLSGETAKGVYPVETVKMMHTICKEAEAAVPNHQHYTSMLDIHPISYLSSETLAGSAVNAAFTQHLKAIIVYSVSGRTARLASKYHPNCPIICVTNNPSVA...................................................................... 290
790 0.000e+00UniRef50_K1RFW7 Pyruvate kinase n=7 Tax=Bilateria TaxID=33213 RepID=K1RFW7_CRAGI  ali  53  1................................................................................................................................................................................................................MIFASFIRSGQHIKDIRSILGEKGKNIKIIAKIENHEGVKRFDEILQESDGIMVARGDLGIEIPPEKVFLAQKMMIGRCNRAGKPVICATQMLESMVKKPRPTRAESSDVANAVLDGADCVMLSGETAKGDYPLESVKMMQKICREAESAVFHHQLFEELRKETPTPTDATHTVAIAAVEASFKCMAAAIIVITTSGRSAHLISAYRPRCPILAITRIEQTARQCHLFRGIFPIHYVDSVMSEWTVDVDRRIYKGIQSGMDRGFIQKGDPVIIITGWKPGSGSTNTMRI... 289
791 0.000e+00UniRef50_UPI000D0C7F78 pyruvate kinase-like n=1 Tax=Halyomorpha halys TaxID=286706 RepID=UPI000D0C7F78  ali  46  66...MQYISNLEVHAGVHYKKAGIICTVGPSSRNVETLVKMMDAGMDVARLNFSHGTHDYHRESIVNIRKAVAIRSGRPIAIALDTKGPEVRTGLLEKSKEELVLAKGKTVLHTEHSFYEKGTQSDLYIDLPSLPSLVKPGSSIYIDDGLIQLTVLKT-DKTSIKCLVENGGLVGNQKGVNVPGVRLDLPAVSEKDKGDIKFGIEQDLDIIFASFIRCKEDVLEIQKFLGEDYERIRVVSKIENHEGVNNIDEIIAISDGVMVARGDLGIEIASERVFLAQKRVIASCNLAGKPVICATQMLESMVKKPRPTRAESSDVANAIMDGADCVMLSGETAKGKFPVECVKIMSDICRASEEAVQHLKVFSEV.................................................................................................................................... 438
792 0.000e+00UniRef50_A0A0S4T5R9 Pyruvate kinase n=1 Tax=Hymenolepis microstoma TaxID=85433 RepID=A0A0S4T5R9_HYMMI  ali  48 1221...........................................................................................................EIIRITPDKYYENCNEKTLYVDYENIVRVLNVGSLIFIDDGLICVRVKEKGAD-YLDCVIENGGRLGSKKGVNLPGSPVDLPAMSEKDRQDILFAVNNNLDMIFASFIRDAKAIYEMRQLMGERGARIKIIAKIENHQGVKNINEIIDAADGIMVARGDLGIEIPPEKVFLVQKMCFERCNFVGKPCICATQMLESMTYKPRATRAESSDVANAVLDGADCVMLSGESAKGKYPVECVRTMSGICREAESVSSRMRPYNGLQSMTKLPAETNLGTAIAAVEASLSIAARAILCITSSGESSRMLSWHRPLCPILCVTRDPVAARQLNLFWGCIPIIYEGKGADCWSEDVNHRIECGINYGLQI-------------GWRSEPGHTNAVRI... 1597
793 0.000e+00UniRef50_C3ZZR0 Pyruvate kinase n=7 Tax=Bilateria TaxID=33213 RepID=C3ZZR0_BRAFL  ali  53  119.........................................................................................................................................................VIDNVSEDYLLCVIDNGGTLGSRKGVNLPRVAVDLPAVSEKDKGDLLFGVEQGVDMVFASFIRKAADVHAVREVLGEKGKNIKIISKLENHEGVRRFDEILEASDGIMVARGDLGIEIPAEKVFIAQKMMIGRCNRIGKPVICATQMLESMIGKPRPTRAEGSDVANAVLDGADCVMLSGETAKGLYPIPSVKMMHAIAREAESAMFHRQVFEELREILWEASDPTQSAAVAAVQASFSCQAAAIIVVTRSGKSAADMSHFRPRCPILAITREAQVARQMHLWRGIHPLWYEEKRKENWVDDVEARVTYCIEYAKNCQLMKVGDTVVIVTGWRPGSGHTNTMRIKCI 467
794 0.000e+00UniRef50_A0A168IDF3 Pyruvate kinase (Fragment) n=2 Tax=Fungi TaxID=4751 RepID=A0A168IDF3_MUCCL  ali  66  16.........MQWIAGMDVRKTSIICTIGPKTKPVEKLVELIDAGMNIVRMNFSHGDYEYHKSVLDNARAAAAARPDKVIAIALDTKGPEIRTGLMLNDTEVPIKKGHQMNITTNEKYATACDGENMYVDYKNLPKVIEVGKNIYVDDGVLSFKVLSKGDD-FVRVEAQNNGKICSKKGVNLPKTAVDLPALSEKDKNDLRFGVENGVDMIFASFIRRAQDVKDIRRVLGDKGKNVKIICKIENHQGIQNFDEILAETDGVMIARGDMGIEIPCERVFIAQK........................................................................................................................................................................................................................... 293
795 0.000e+00UniRef50_G0U4F2 Pyruvate kinase (Fragment) n=2 Tax=cellular organisms TaxID=131567 RepID=G0U4F2_TRYVY  ali  55  1MSQLQHNIGLSIFEPPNYRANRIVCTIGPSTQSVEALKGLMKSGMSVARMNFSHGSHEYHQTTIKNVRQAAEL--GLHIGIALDTKGPEIRTGLF-KDGEAILCPGETVLVTTDPAFEKNGTKEKFYIDYPQLTTAVRPGGHIYVDDGVLNLKVLSVEDDCTLKCYVNNHHRLTDRKGCNLPGCDVELPAVSEKDRKDLIFGVEQGVDMIFASFIRTAEQVREVRAVLGEKGKDTMIISKIENHQGVQNIDAIIEASDGIMVARGDLGVEIPAEKVVVAQMCIISKCNVAGKPVICATQMLESMTTNPRPTRAEVSDVANAVFNGADCVML......................................................................................................................................................................... 330
796 0.000e+00UniRef50_A0A182EKN8 Pyruvate kinase n=4 Tax=Nematoda TaxID=6231 RepID=A0A182EKN8_ONCOC  ali  54  1..........................................................................................................................................................MNLLEDEGVICTVENGGMLGSRKGVNLPGTVVDLPAVSEKDIKDLQFGVEQNVDIIFASFIRNADGIRIIRKVLGEKGKHIKIIAKIENQEGVDQADGIIEEADGVMVARGDLGIEIPPEKVFLAQKMLIAKCNNAGKPVICATQMLESMVKKPRPTRAEGSDVANAVLDGADCVMLSGETAKGDYPLEALKIMHQICREAEAVIYHTRFFEELLHMTPKPTDIAHTVAIAATSAAASCHASAMILVTTTGRSASLVSRYRPMMPIFAICRDGHVARQLHLWRGIFPLHYGASRESDWSSDVDARINYGISVGKERGFIKKNDLVVVITGWRQGAGHTNTLRIIKV 346
797 0.000e+00UniRef50_L8WYL4 Pyruvate kinase n=1 Tax=Thanatephorus cucumeris (strain AG1-IA) TaxID=983506 RepID=L8WYL4_THACA  ali  65  231............................PKVNNVEMLGQLRKAAISPTLTPFHDSPNELFPRIIRVPPKSEEPDDARPLAIALDTKGPEIRTGAISRSQDVKISAGHEFIVTVDPQYAESCDDKRLYMDYANLPAVTSPGKLIYVDDGILSLLVLSI-DGKDVHVRAVNNGTLSSRKGVNLPKTPVDLPALSEKDKKDLQFGVKNGVDMVFASFIRRAQDVIDIREVLGPDGAAIKIIVKIENEQGVENFDEILREADGVMVARGDLGIEIPASQVFIAQKMMIAKCNIAGKPVICATQMLESMTYNPRPTRAEVSDVANAVLDGADCVMLSGETAKGSYPIQS............................................................................................................................................................ 556
798 2.000e-97UniRef50_J9NV90 Pyruvate kinase n=12 Tax=Bilateria TaxID=33213 RepID=J9NV90_CANLF  ali  47  41..............................................................................................................ITLDNAYMEKCGEDILWLDYKNICKVVEVGSKVYVDDGLISLQVKQKGAD-FLVTEVEKGGSLGSKKGVNLPGAAVDLPAVSEEDIQDLKFGVQQDVRRVFASFIRKAADVHEVRKVLGERGKNIKIISKIENHEGVRRFDEILEASDGIVVARGDLGIEIPAEKVFLAQKMMIGRCNRAGKPVICAHRCWRARSGEPVP-RAEGSDVASAVLDG-DCVMPSGETADGDYP-EAVRRQHLIAREAEAAI-YHQLFERLRCLAP----ITRDPAEAAALAPWRPPARAVIVLTECGRSAHQVARHRPRAPII-ATWNPQTARQAHLYRGI-PVVC-KDPVQEWAED-DLRVSLAMNVGKAQGFFKKADVVIVLTGWHPGSSFTNTMRVMPV 421
799 2.000e-96UniRef50_A0A2P8ZPK6 Pyruvate kinase n=1 Tax=Blattella germanica TaxID=6973 RepID=A0A2P8ZPK6_BLAGE  ali  44  31...........................GPSSKSVEKLEQMLECGMNIARMNFSHGTHEYHAETVRNVRQAVNNYSKR------------IGYMHSGGSAEVELVKGNNITLTTDPSFEEKGTQDCVYVDYQNITN---------------------------------NGGMLGSKKGINLPGLPVDLPAISEKDKGDLEFGVEQEVDIIFASFIRNGSALKEIRDIL-----ELEFLIRLCDKIKSSFLARFLKIAVAVNVLRKWILYKVTV--YIFLQK---------GKPVICATQMLESMTYKPRPTRAEVSDVANAVLDGADCVMLSGESAKGTYPLETIQTMANICKQAENSV-WLKQVD-------IPIDPAHAIAVAAVEVSQKTQASAIVVITTSGLSAQLVSRYKPRCPILAITRHAKAARQLNLWRSIIPLYYITPPTQDWMKDVDARIQFAITYGKVMGFIKPGNAIVLVSGWKQGAGFTNTLRV... 431
800 2.000e-96UniRef50_A0A0M3JXJ7 Pyruvate kinase n=6 Tax=Ecdysozoa TaxID=1206794 RepID=A0A0M3JXJ7_ANISI  ali  53  5.TQLEYLSALKLKDTTHFRKTGIICTVGPACRSVDMLRTMITNGLGIARLNFSHGTHEYHAETIANIREA-----GVQAEV-------ELKKGSS-------------VIITTDPKFQNSCTSVNIFVDYVNIVKVLKEGSRIFIDDGLISLLVNEI-GKNSLTCTVENGGMLGSRKGVNLPGTRVDLPAVTEKDIDDLKFGIEQGIDIVFASFARSGEGIRQIRRALGETGKHIKVIAKIENQQGVENAEDIIAESDGVMVARGDLGIEIPAEKVFLVQKMLIAKCNRYGKPVICATQMLESMIHKPRPTRAEGSDVANAVLDGVDCVMLSGETAK................................................................................................................................................................... 315
801 3.000e-96UniRef50_B8BVN3 Pyruvate kinase (Fragment) n=5 Tax=Bacillariophyta TaxID=2836 RepID=B8BVN3_THAPS  ali  40  1......................IVATIGPTSEQLPVLQDIVRCGMRVMRLNFSHATGRH--SIFNSNDEEQITSTGESTAVLLDTRGPEIRMGKLAND-----HSGHETVHTSNDVRDNGSTASQLYIDYPKLHECLVPGMKVLLDDGAIILTVVQVEANGSVSCSADNSGELRSRAGVNLPGAETDLPAMSDKDKVDIKYGMTKDVDYVAASFIQNAEGVREIRAYMEQCARELLIISKIESVSGLNHFDDILEESDGIMVARGDLGVEIPIQQVTNAQKEMVAACNAVGKPVIVATQMLESMAKNPRPTRAEVADVTNAIYDGADCVMLSGETAKGKYPVQVIQMMNEIISSAEHFTTSMPGPNLMAQGQKGSNSVDGALAKSAVTAAEERDAAAIVVLTSHGVLPRLISAYRPNIPILAFCDSTKVAKQLMLHRGIHPIHVGNDIINNVTVKRPAR---AIQYAKQFGMVQEGDNVVVV.................. 486
802 3.000e-96UniRef50_A0A183CWQ2 Pyruvate kinase n=1 Tax=Gongylonema pulchrum TaxID=637853 RepID=A0A183CWQ2_9BILA  ali  54  1......LCKININAGHTFRKTGVICTIGPACQSVGKLKEMMTAGMNIARLNFSHGSYEYHGETIKNVREAAQSFPEKMLAIALDTKGPEIRTGFIVNDAEVGLKKGEKIRLTTNCAMATRCTAQVLYVDYQNITKVLKPGAHVYIDDGLISLMV-DSIQGQDIMCTIENGGKLGSKKGVNLPGTKCDLPAVSAKDTKDLQFGVEQGVDMIFASFIRNADGIRAIRRVLGEKGHLIKIIAKIENQEGVDNADEIIREADGLMIARGDLGIEIPAEKVFAAQKMLIARCNVAGKPVVCATQMLESMTKKPRPTRAE.......................................................................................................................................................................................... 362
803 6.000e-96UniRef50_A0A0C2MGB7 Pyruvate kinase n=4 Tax=Thelohanellus kitauei TaxID=669202 RepID=A0A0C2MGB7_THEKT  ali  35  38...............SGFKSSAIICTIGPSCDRSEIVHEMIREGMCVACFNLSKGTQLEHRSRLDLVRTGSKFGENSSLAFAIDINGSEIRTGTNLNQLDINLIEGQGIIITTDSGFKGECTSEKLYIDYKNLIDSINSGQIILIDNGLVVLEVKQLRRDDVV-CRVIKGSTLGSQRNVILPGVKNLLPVLTAKDRNDIIFAINEKVDILFIPNFRDIGDVSDLRELIQDHGRKMKIIYKVSDHVGVTKINELIEVSDGVLIDRTNLTLDIGSERTNIAQKMIISLCNLAGKPVICGGRVLESVNVTAETTSPETSDVINAIWEGVDGLMLFEKTANGKDPVNAVKMLNSICLAAEKTHRTRRHLEAIKN-SLRCATEEQAIAIAAVEISYSLKTDAIIVLTTTGRTAEMVSMFRPRCYILAVTRTPEVARWLHLYRSVCPVLYTKGRIEPWVDDVEARIKFAVHYGTKHGSLHIGSNVVLITGWKSGAGSTNYIRIASV 523
804 8.000e-96UniRef50_A0A1W4VMG7 Pyruvate kinase n=2 Tax=Drosophila ficusphila TaxID=30025 RepID=A0A1W4VMG7_DROFC  ali  43  1............................................MRVVRMDFSQYNHECHCKTIEATRKAMEMYAERTVAIALDTKGPGIRTGKLAGGTEIKLLPGDKITLSTKKELEEKCTKEQIYVDYQPLPSVVKPGNRILLNDGFIQLVVKESADEVTCQVET--EGRLGSHQGVNLPGIPLDLPSVTEQDKLDLKFGAELPVDMIFASFIRDANALKEIRQALGSTGEHIKIISKIDSQQGLANLDSIIRESDGIMVARGNLGNEIPEEQVPLAQKSIVAKCNRVGKPVICAGQMMESMTTKPRPSRAEASDVANAIFDGCDAVMLSSETSEGKYPVECVQTMARICAKVESVLW----YENLQSSLKREIRTSAADHISAVTTAISEQAGAIVVASPCQMVSQMISHMRPPCPIVMLTGYPSEAAESSLFRGVYPLLVEE...................................................... 408
805 3.000e-95UniRef50_W7TUU8 Pyruvate kinase n=1 Tax=Nannochloropsis gaditana TaxID=72520 RepID=W7TUU8_9STRA  ali  44  61....................TRIVCTIGPASESLETMQSLADEGMKIGRLNFSH-AVKYDE-------MSEKLRTFRSLKGALDTKGPEIRTGSFVGGVKHEIPSGAQVILTTDPAWADKGTPEKIFVDYRALGRTCVKGGNILLDDGIIKLEVVEPVTETLCVVKNRNPVSLGARKGTNIPGAILELPALTGRDKADLEWGVDNDVDFVAASFVRKAADVRSVLERLMAKRKPTEVISKVENAEAIKNFDEILAESDGIMVARGDLGVEVPFQDVFTAQKMMVKKCNDAGKPVIVATQMLDSMMRNPRPTRAEVSDVGNAVLDGADCVMLSGETAAGKYPVESVQAMRNCVVRADTTVDHPDTIVDVRTTRPGLTSELETVALCTVVAASELQADLIIVLTTRGNFARAVAKHRPQIPVMVFCSELKVARQLQLFRGLFPVLLQGATVED--------IPEAIRTAKEIGWVKAGDKVV.................... 562
806 4.000e-95UniRef50_Q9I8C5 Pyruvate kinase (Fragment) n=3 Tax=Bilateria TaxID=33213 RepID=Q9I8C5_TRASE  ali  55  1............................................MNIARLNFSHGSHEYHAGSIENIREATESFTSRPVAIALDTKGPEIRTGVVKENMEVELVKGSRVTVTTDDAFKECCDQANIWVDYKNLPNVVKVGGKIFVDDGLISLLVKEIRADSCI-TEVENXGMLCSRKGVNLPGAEVDLPAVSERDIRDLHFGLQHGVDMIFASFIRKAADVAAIRDVLGERGRAIKIISKIENHEGVRKFDEILEASDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNRAGKPVICATQMLESMIXKPXPT............................................................................................................................................................................................. 273
807 4.000e-93UniRef50_A0A0R3R2E0 Pyruvate kinase n=1 Tax=Brugia timori TaxID=42155 RepID=A0A0R3R2E0_9BILA  ali  52  130..................RKTAIICTIGPACGSVDNLKEMISSGMNIARLNFSHGSHEYHATTIKNIREAVQSFHQKPIGIALDTKGPEIRTGLISATAEIELKKGAKIKLTIDKAMASKCNANILYVDYENMPKILNPGAHVFIDDGLISV-VVDSIQGKDIMCTIENGGKLGSKKGVNLPGTKCDLPAVSDKDTKDLKFGVEQGVDMIFASFIRNAEGVRTIRRILGEKGRFIKIIAKIENQEGIENADEIIREADGLMIARGDLGIEIPTEKVFAAQKMLIARCNLMGKPVVCATQMLESMTKKPRPTRAE.......................................................................................................................................................................................... 447
808 6.000e-93UniRef50_A0A060XQY8 Pyruvate kinase n=4 Tax=Bilateria TaxID=33213 RepID=A0A060XQY8_ONCMY  ali  55  44..................RNTGIICTIGPASRSVDMLKEMIKSGMNIARMNFSHGSHEYHCETIKNVREAESFEPGRPVAIALDTKGPEIRTGSGTSEVE--LKKGNMIKLTLDDAYQENCDEDNLWLDYKNITRVVELGSKIYIDDGLVSLQVKEIGGD-YLICEIENGGTLGSKKGVNLPGAAVDLPAVSEKDISDLTFGVEQGVDMVFASFIRKAADVHAVRKVLGEKGKNIKIISKLENHEGVRRFDEIMEASDGIMVARGDLGIEIPTEKVFLAQKMMIGRCNRAGKPITCAT.......................................................................................................................................................................................................... 329
809 9.000e-93UniRef50_D3T9H6 Pyruvate kinase n=2 Tax=Aciduliprofundum TaxID=379546 RepID=D3T9H6_ACIB4  ali  43  1.................MRKTKIIATLGPAVKDDSTLISLIKAGVDIARLNIAHGSVEEHKNMKDKFEKSEEL--GKNTAIMLDIKGPEIR------------------ITRCKKKFVKK-GDRIDIGDFGDIENYLSPNTYVLIHDGEIKLQIKEI-KDKLAIAEVVEGGIIAPHMGVNVPGVSIPIPYIQERDLEFIK--ALAPIDFIAASFIRSASDIVALRKVMDEIGLKGQIIAKIENQEGVNNIEEILEISDGIMVARGDLGTEIPVENLPQIQKYLLKKAIEYGKVGIIATQILESMIRNPLPTRAEVSDIANAVLDGADALMLSGETAIGKYPIEAVKVLAR---VAERADIMIEN----KNLLELKGSLSECVSNAAVLLANEIDADAILVLTRTGKTARLVSRHKPPMQILAATYSKKTLRSCSIYWGVNAFLIDKFGYA------ENALKNAIEKAEKDGLLKRGDVIVIAGGEPSGIGTTNFVWVQLV 455
810 1.000e-92UniRef50_B7G961 Pyruvate kinase n=3 Tax=Bacillariophyta TaxID=2836 RepID=B7G961_PHATC  ali  41  36....................TKIVCTIGPASDQAESLGQLVTYGMSVARLNFSHAGDDYNMALLRNAGKHHHLATGSSTAILVDTKGPEIRTGILPGDVEMDIPVGATVMLCIEDQEVLAEGEFKIHVDYESIAKTVKIGDKVLLDDGLIELEVMEVHGSGTVLTSALNGGPIKKNKGVNLPGVQLDLPALTDKDKRDLDWACRVGADFVAASFIRTPANVRSVIAYLGMKPLRPLVISKIESKEGVDNFDEILEESDGIMVARGDLGVEIPYSKVFAAQRMMVHKCNEIGKPVIVATQMLDSMMRNPRPTRAEVTDVGTAVMDGADAVMLSGETAAGKYPIESIRAMASVAWEADQIVSSIVWNEDLHEKMDLMEQELDAVAASAVRSAQDMGAKMIVLITMSGRVARAVARHRPTVPVLAYCTDVQVARRLQLHRSIIPIMLQSE--AD-PGDSSTRMGYAVRTAKELGFAHSGDRIIMV.................. 529
811 3.000e-92UniRef50_A0A151Z3Z5 Pyruvate kinase n=1 Tax=Tieghemostelium lacteum TaxID=361077 RepID=A0A151Z3Z5_9MYCE  ali  43  2..................................................................................LDTKGPEIRTGKIEDRQGYDLQVGQEII--VDTNTSQPGNINRISIDYKDLVNSVKVGGYILIADGVISLSIVAVEKEKGYCLRVNNNSRLGENKNVHLPGAIVNLPALSEKDIDDIKFGVEQKVDFIAASFIRKAEDVLEIKQILGAARDDIHIISKIENVEGVDNFNEILEVSDGIMVARGDLGVEVQMEKIFVAQKMIVSKCNSVGKPVITATQMLESMIKNPRPTRAEATDVANAVLDGTDAVMLSGETASGDYPFEAVDIMAKIAELVESSTDYQSLFAALKMSTPKPISIAETVASYAVATAIDLKADLIITLTETGLTTRLVSKYRPPMPVFAVTSWRHTVKHLLATRGAISFLVESLV---GTDNL---VDNCIEYAIKNNLCKVGSRVVIVSGVMEGVGKTNNMKIMQV 417
812 3.000e-92UniRef50_A0A146UL94 Pyruvate kinase (Fragment) n=4 Tax=Fundulus heteroclitus TaxID=8078 RepID=A0A146UL94_FUNHE  ali  54  2..............................................................................................................................................................................................VSEKDIDDLRFGVTNDVDFVFASFIRNAEGVREIRKVLGEEGRHIKIISKIENCQGLENIDSIIRESDGIMVARGDMGIEIPAQKVFVAQKTIIARCNLAGKPVICATQMLESMTYSPRPTRAEVSDVANAVMDGADCVMLSGESAKGNYPVECVRLMHEIAKEAEACIFYREVFENLRYFTPPPIDAVEATSIAAVEASFRVYARVILVLTSTGTSAMQISKYKPMALIMAITRNERTARALAIHRGCYSVHYEKQSVGDWLVDVDARVREGMRIAKQNKFVEKG........................ 323
813 4.000e-92UniRef50_G3RT40 Pyruvate kinase n=3 Tax=Homininae TaxID=207598 RepID=G3RT40_GORGO  ali  45  57....................TGIICTMGPASPLLEMLKKTIKSGMNVAHRN-SHGAHEYHTETIKNVCTATESFASQPIAVAPDTKGPEIPAGPVKGS------------GTAEVELKKG---NILWLDYKNICKVVEVGCKIYVDDGLISLQVKQK-DAHFLVTEVENGGSLGSKKGVNLPGAAVDLPAMLEKDIQDLKFGGEQDVDMMFSSFICKTSDIPEVRKVLGEKGKNSKITSKIENHDGGWRFDEILEASDGIMVAHGDPPQAIPAGKVFLAQRMMIGWCNQAGKP------MLEDVIKKLHPTWAEGSGVANAVLVEADSIMLSGETAKGNYPLEAVHMQHLIACEAEATIYHLQLFEEFCHLAPITSDPAEATAVGTVEASFKCCSGAIIVLTKS------VARYCPRAPMIVVTWNPQAARQAHLYHSIFPVLFKKDDV................................................... 463
814 6.000e-92UniRef50_B8LD52 Pyruvate kinase (Fragment) n=2 Tax=cellular organisms TaxID=131567 RepID=B8LD52_THAPS  ali  43  2....................TKVICTLGPSTDSKEMIDKLVSHGMTVARLNFSHAGYTYPTKLMED----DGVYPKNIRAILVDTKGPEIRTKPLQGNVDIAEIASGAMVITTEDVSGDSPPSSRIQVDYESIASTMEIGSKILLDDGLIELEVTDIDNSRSLQTIALNGGPIKKNKGVNLPNTAIDLPALTEKDKRDLKWSCEQGADYVAASFIRTGANVRSLQDV-NPKKKFMRVISKIENKEGLDNFDEILHESDGIMVARGDLGVEIPFREVFAAQKMMVERCNRVGKPVIVATQMLDSMQKNPRPTRAEVTDVGTACLDGADAVMLSGETAAGKYPLESIKAMK--GVLSESEEIKLAKKDVYFHDRDITTSSR----TSAVKTALEMDVKAIIVLSQTGTTARAVAMHKPCVPVLAFCTDIQVARRLQLHRSV............................................................. 422
815 1.000e-91UniRef50_H1AGA7 Pyruvate kinase (Fragment) n=6 Tax=Bilateria TaxID=33213 RepID=H1AGA7_URSTH  ali  53  15..................RSTSIIATIGPASHSVESLKEMIKAGMNIARLNFSHGSHEYHAQSIANIREAVESFATRPVAIALDTKGPEIRTGVLQGEAEVELVKGSRVLVTVDPAFRTRGDANTVWVDYPNIVKVVPVGGRIYIDDGLISLQVKKI-GLEGLETQVENGGLLGSRKGVNLPGAEVDLPGLSEQDVLDLRFGVQHNVDIVFASFVRKASDVATIRAALGPEGRNIKIISKIENHEGVKKFDEILEVSDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNLAGKPVVCAT.......................................................................................................................................................................................................... 300
816 6.000e-90UniRef50_A0A291ISY9 Pyruvate kinase n=1 Tax=Mesoplasma lactucae ATCC 49193 TaxID=81460 RepID=A0A291ISY9_9MOLU  ali  41  10.................VKRTKIVTTIGPATHNTEDIQKLYENGMNTIRLNFSHGSYDEHGARIASAKSLRE-SKNEPISIMLDTKGPEIRVGKFKDGAQQVSAGQKITIYTDADSYAKDCGQGEMTVAY-DMSQDLKPGDVVLIDDGKLEMTV-DSVKPGVVMCTAFNPHVVKTNKRVNLPGVDFSMPFLADKDKADLKYGCEQKVDYVAASFVNTADNIKEIRDIFANNQEDIQIFAKIESQVGINNIDAIIAAADGIMVARGDLGLEIPYWEVPQWEKIIIEKCRVAGKPVIVATQMLDTMTDNPAPTRAEVTDVYEAVMFGADATMLSGETAAGSYPFITVNTMATIDKRAEIDFYDQANYKALVEQSRKTTTGANADIASKVSDLFDGKYQFAVVLDEDGALLKTLSKFRPNLAILGVSTSER........................................................................ 420
817 1.000e-89UniRef50_F0YHP3 Pyruvate kinase n=1 Tax=Aureococcus anophagefferens TaxID=44056 RepID=F0YHP3_AURAN  ali  40  30....................TKIVCTLGPSSETAERVQELVDNGMTCTRLNFSHGDYSEPAGKLALARLANDLPPNL-RAVLVDTKGPEVRTG--------PLPGNADVLEIADGTFADVSGDAPLHVDYESLPSTVSVGGLVLLDDGLIALRVTSI-ETTGVTCVAENAGPIKARKGVNLPDTILDLPALTAKDKEDLAWSVDVGADYVALSFVRNASNVRSCRAFLARAGSDAPIVSKIENQEGVDHFDEILEASDGIMVARGDLGVEIAYAKVFAAQRMMVAKCNAAGKPVIVATQMLDSMMRMPRPTRAEVTDVAAAVLDGADAVMLSGETAAGKYPVQALAAM--RAICAEA--------DAIRDAAP-PNAAVEPLADVELDAVAKAAAKLITCITMSGSLARAVARHRPNAPVLAFCYSADVARRLQLHRAIHPVLLDACATDQNPYLAGTRMGLSIRASKELGHIKDGDRVVSV.................. 503
818 1.000e-89UniRef50_A0A063YG60 Pyruvate kinase n=7 Tax=Mollicutes TaxID=31969 RepID=A0A063YG60_9MOLU  ali  40  6..................QRTKIVATIGPSSNNHKTLTELVKAGISTVRVNFSHGTEETHKQVYDLARQSKEL--GVPISLLLDTKGPEIRIGKMKDDI-CKITANTEITIKTDENYLNLIDEKTITVSYRNDTVLLDDGKLVTIVKEVKPFQII---------VVAKNSHMLKTNKRVNIPGIDFSMPFMSERDKNDIIWGIKYGIDIIAASFVNSAANVNQIRQILKENGENIEICSKIESKKGIDNIDEIIAASDSIMIARGDLGLEIPYYDVPYYEKKIIRKCRLAGKQVIVATQMLDSMEKSPLPTRAEVTDVYYAVELGADATMLSGESASGMYPVEAVKTMATISQRAEQEYYNEHFYNIQIEAVSKDAKSREIIAYEVAKKLKDGKFKFGVVISHTGKLLKEISKYRPNAFIAGIVSDDNLVRKYGITSGIYSELLRAEIKQDHAAAKKALEKFNIQKGDKF.............................. 460
819 1.000e-89UniRef50_A0A287HSS3 Pyruvate kinase n=7 Tax=Embryophyta TaxID=3193 RepID=A0A287HSS3_HORVV  ali  45  29....................................................................................SSGPEIRTGFLKDGKPIKLTKGQEITVSTD--YDIKGDTNTISMSYKKLPQDVKPGHVILCADGTISLAVLSCDPEATVRCRCENTAMLGERKNCNLPGIVVDLPTLTEKDKEDLGWGVPNDIDMIALSFVRKGSDLVTVRQLLGQHAKRIKLMSKVENQEGIVNFDDILRETDAFMVARGDLGMEIPVEKIFLAQKMMIYKCNLAGKPVVTATQMLESMIKSPRPTRAEATDVANAVLDGTDCVMLSGESAAGAYPEVAVKIMARICVEAESSLDNDAVFKEMIKAAPLPMSPLESLASSAVRTANKARATLIVVLTRGGTTAKLVAKYRPRVPILSV............................................................................. 367
820 3.000e-89UniRef50_A0A196SGI2 Pyruvate kinase n=1 Tax=Blastocystis sp. subtype 1 (strain ATCC 50177 / NandII) TaxID=478820 RepID=A0A196SGI2_BLAHN  ali  40  22..................RNTKIVCTLGPACWDVDTLVQMIDAGMNVARFNFSHGTHETHGKAHDNLMEALKRRPNKRVAVMLDTKGPEIRTGFLVDGKNITIEKDSIVEITTD--YTIKGDCHKISCSYKDLPTSVKMDQLIYVSDGDLTFQVVEI-GKESIKCRALNTATIGETKNMNIPGAIITLPTLTESDIHDIDFPKHYRVDCIAASFIRKASDIDNIRKILGPELQHIQIIAKIENQEGLQNYEEILEKVDGIMVARGDLGMEMAPEKVFLAQKYMLHEAALKGRFTITATQMLDSMIRKPRPTRAECTDVANSILDGSDAVMLSGESANGLYPVKAVTMLRKLSEEAEKVYPYMRCR--MRGSQKYGVSEVEEACYEGVMRAEEMRAQAVVVMSHGNELARWVSKYHIAQPIFVMT............................................................................ 427
821 7.000e-89UniRef50_A0A2H0I4J5 Pyruvate kinase n=1 Tax=Candidatus Gracilibacteria bacterium CG12_big_fil_rev_8_21_14_0_65_38_15 TaxID=1974579 RepID=A0A2H0I4J5_9  ali  36  7.................MKKTKIIATVGPVTESEEQLIALYKAGVNIIRFNFSHANYEVARAIMGRIRKLNS--EGKTLSTLLDTKGPEIRTGDLKSKIQFE-KGDVIKIYTDISKFSN--DSMSLFCDYISLVEDVNIGQIIRIDSGLFDVEVVEKTSD-YIRVIALNSCLIGSRRHVNLPGVKLRLPGITGQDKKDVLFSIEEGYDFIAMSFVRNCSNVEELRNLLSEHASHIKIISKIENQEGIENLDEIIEASDGVMVARGDLGIEVPIEKLPVYQLEIVKKSMTQGKFVIVATHLLETMIENPFPTRAEVSDIFNCVRQCTDCTMLSGETTIGKYPIKTVEMM--TAVINEAEANMIYEHKDFSDCTRDIEK--KHLIKNALITSESINARVVLIFTKSGRLARFAAAFRPNKDVYAFTMNESSVRYMNALFGIRPML-----LGNWTPNLGENLDNAIALLKEKNILSVGDRVIAVNDIQKEGKEIPVMEIITI 479
822 1.000e-88UniRef50_A0A2P6KFM0 Pyruvate kinase n=9 Tax=Eukaryota TaxID=2759 RepID=A0A2P6KFM0_NEPCL  ali  48  18..............................................................................................................................................................................................................VDMVFASFIRNAAGVNEIREILGDEGKHIKILPKIENHEGVKKIDEIIEASDGIMVARGDLGIEIPTEKIFLAQKMMIAKCNIAGKPVICATQMLDSMVKKPRPTRAESSDVSNAVLDSSDCVMLSAESAKGEYAVTCIDVMHAICREAEAAFFHRHVFNDLILQLKLPTDQTTGIAIAAVTAAMKIMASAIIVLTHSGRTAHLMAKYRPRCPILAVTREAVTARQAQVYRGIIAIHYTEEENSDFIEDVKNRIDYALDFGKKRKIFHSGNIIVTITGWRTGKGATSTMRVIVV 311
823 2.000e-88UniRef50_UPI00040A2C47 pyruvate kinase n=2 Tax=Acholeplasma TaxID=2147 RepID=UPI00040A2C47  ali  40  1.................MEKTKLVGTMGPASEPKDILREIFKAGLNVARMNFSHGDYEEHGARIKTVRENEEL--GTNVALMLDTKGPEMRTGAVIIEKGDEVKVVFEQVLGTKEKFS---------INYPGLYDDVEVGTVLLIDDGYLQTDVIKNAKDRSITIKARNTHRIKNRRGVNVPNTKINMPFLSEKDRNDIIFGAQVGVDFIAASFVQTAEDVLSIKALLKEKAEQIQVIAKIENQEGVDNLDEIIEAADGIMYARGDLGVEILPEDLPHLQKEVVEKTRQAGKLIIVATQMVESMQNNPVPTRAEVSDVANAAFDSADSVMLSGEMAAGKYPLEAVKMMKRIVKANEKYV----DYDNFVFPLYVSADDIENVAFMATISASTHDVRAIVV--DNAELAGAVSKYRPQA-FVIPTVTHDEARKLNLRFGVYPVVGKKD..................................................... 420
824 2.000e-88UniRef50_A0A0D8HKU4 Pyruvate kinase n=1 Tax=Acidithrix ferrooxidans TaxID=1280514 RepID=A0A0D8HKU4_9ACTN  ali  39  5..................KKTKIVATLGPACANIDTVVAMAKAGMNVARLNLAHGTPASIVRLIGLVRRAER-HTGKMISILADLPGPKMRIG----KLDQAIGLKGGMTVRLAPTGSPAVDNDIIPVDFPGIARAVGPGSLIYLADGFISLKVVRVEGESILCTVA-AGGELSSHKGINLPGATLDISSLTDKDAELLYFALSRGADALSISFVQRAEDLHRARAIAGEHGFSPFLFAKIEHPAALRDIDAILNACDGIMVARGDLGIELPLEEIPLVQKDLIFRANCIGKPVITATQMLESMVDSPRPTRAEVTDVANAILDGTDAVMLSEESAMGKYPVEAVATLAKVARYTEEHATFIPSRDYMRD---HATTIPEIVALSVLSAVEKLDPDYIVTPTESGSTPRSIAKFRMKPWIVALSREETTARRLAFTSGVAPLVIKPH---DTTWEIKTR......................................... 438
825 3.000e-88UniRef50_A0A2G6DQE0 Pyruvate kinase n=2 Tax=Candidatus Moranbacteria bacterium TaxID=2045217 RepID=A0A2G6DQE0_9BACT  ali  38  8..................KHTKIVATLGPVSESVEVLEKMIKNGLNVTRFNFSHGEYEWHERVMNNVRMAAK-NVGVPIAILADLQGPRVRTGETVRICD---------ISMDDEEIAKFSDQKVITLDCPKIIDSIAVGNDILIEDGLMKVKIVDIMDGYAV-ADVIDGGVIKNHKGVNIPDARIPLPTVTKKDYDDLAFALAHDVDYIALSFVRNGQDIVDVRKILGDEVSLPKIVSKIECKEALNNLERILCATDAVMIARGDLGIEMNPARIAILEKDILEKAIRHMRPVIVATQMLASMEHNPRATRAEISDVTNAVADHADAVMLSGESSMGTYPVDTVRTMAEVATQTE-----ISPYDDVFDAMPLTFSSEEVIAHGTYDFARELEAQAIVIYSESGYTARLLSHFRPDQNIIVVTNNQKTYHQLALPWGVKSFMCPGEQSR------EKCIENAIQQAKEKGVLHTGDLVITVLG................ 467
826 6.000e-88UniRef50_A0A1F6RN78 Pyruvate kinase n=1 Tax=Candidatus Moranbacteria bacterium RIFCSPHIGHO2_01_FULL_55_24 TaxID=1801638 RepID=A0A1F6RN78_9BACT  ali  39  5..................KQTKIVATIGPASESKAMLRALVNAGMNVVRLNFSHGEHAWHQEVINRVRESLELKT--PIAILADLQGPRIRT-----EIAAPLELEQGAKVTVSDISHKESGENIVFLDIPGIIDHVEVGHALLIEDGTLELTVT-AKEEKSLTAETKSPGTIKTRKGVILPDSEITLPIISEKDKRDLEFILGEGVEYIALSFVGSAEDIATVRAQMKAYASDEKIVSKIERKEAIRNLQSIIAATDAVMVARGDLGIEMPESEIALLQKKIIRESLKAAKPVIVATQMMKSMTENPRPTRAEVSDVSNAVIDHTDAVMLSEESAMGRYPVETVAMMSEIIQKTEES-----PFDDLYHALDKNEYSTMIRSVYQLAQSF--RTKAILILSISGFTARLLSHFRPESRLLVATNDRRVWNELALVWGIDPYLFEGDERYD------THTTLLMEEAKKDGKISAGD....................... 452
827 6.000e-88UniRef50_A0A074Z476 Pyruvate kinase n=1 Tax=Opisthorchis viverrini TaxID=6198 RepID=A0A074Z476_9TREM  ali  33  41.SQLEHVSQLDIVSGF-VRQATIVCTLGDRWNNDKSIESMIQGGMNILRLNMSMGSYEYYADVIRRVRAIEQASNYKPVGIAIDISAPPIRTGIINNDVEVTLKDGQFVKLTVNNEFQNATSEELIYLDFPCLVQCVSVGDRIHLDDGMLSLIVRDVTS-TTISCLVEQGGQLGGGKRVDLPSERLYQKTFKTTYQRDLAFACESKVDYVFTEYSFTPQQISEARAILGDK---IRLFAKVQSKESIRNLLDIISVSDGIIVGRNGLGLVYPAEKIFQLQKQIIAICNLMQKPVFVISQLLESMRFKPRATRAEISDVANAVIDGADGLILTVETSRGLFPKEAARVLHKTCREAESAI-YHEKYSDIHGLSPRSDPAYLT-ALAAVEASTASRASAIFVATATGQSASTIAAFRPSCPVVAVVRDVQVARWCHSFRGIHPFLYLEEQLEDWCEDMDASMNAAIDYARSRLFVSGGDRVVTVTGWKAGPGATNTVRV... 544
828 7.000e-88UniRef50_C1E8P1 Pyruvate kinase n=1 Tax=Micromonas commoda (strain RCC299 / NOUM17 / CCMP2709) TaxID=296587 RepID=C1E8P1_MICCC  ali  42 1163...........VTTGDTVRKTKIVCTMGPKCWDEESMSKLIDAGMGVARFNFSHGDHEGHGEVLHRLRTVIK-KKGSNTAVLLDTKGPEVRTAMLKDHQPIELEAGQDIIYLTWEGYKTPEETKI-GCSYAKLCQSVKPGNRLLFADGSVVIEVVEILDEKNLKGKVLNSKKLGERKNGNLPGVKVELDVLQPKDIEDIKFACPNQMDYIAVSFVQTGDDVQMVRKLLDENGENIQIISKIENEEGMRNFDDILKYTDGVMVARGDLGMEIPSEKVALAQKMMITKCNIAGKFCICATQMLESMCDNPLPTRAEMLDVANAVLDGADATMLSGETANGAFPEKAVATMAAIAANAEEGVDRCQIYNFIRDFTPMPVGSIEAVVSCAAKTAVDLGAACIVVFSELGFRANLASKYRPAVPIVVVTSLDHVARHTNTAYGQYAF.......................................................... 1603
829 8.000e-88UniRef50_A0A0W8DJA7 Pyruvate kinase n=2 Tax=Eukaryota TaxID=2759 RepID=A0A0W8DJA7_PHYNI  ali  42  24..................RKTKIFCTLGPACWSEEGLLELIDAGMNVARFNFSHGDHASHLACLNRLRAALAKRPNKNVAIMLDTKGPEIRTGFLANKDKVTIQKNSLIELTTD--YEFLGDETKIACSYPQLPESVKVGGSVLVADGSLVLTVTEIKDNGIV-CRANNTATLGERKNMNLPGCKVLLPTLTEKDEDDLNFGLVHGIDYIAASFVRTGQDIDNIRKVLGPRGRGIKIISKIESHEGMENFDEILAKTDGIMVARGDLGMEIPPETVFLAQKMMIRKANLAGKPVVTATQMLESMIARARP--------------------------------------------AETAIHYNDVYQSLRNAVLEPMETAEAVASSAVKTAIDINAKMLVVLTETGNTARLVAKYRPEMPVLVLTALEQTARQTEGFKGVVSRCVGSMI---GTDSILYR---ATEAGKDLGWLKKGDAVVAVHGIQAKSGSTNLLKV... 456
830 2.000e-87UniRef50_UPI000711F91B pyruvate kinase n=1 Tax=Blastocystis sp. subtype 4 TaxID=944170 RepID=UPI000711F91B  ali  39  24....................TKIVCTLGPACWDVDTLVQMIDAGMSVARFNFSHGTHETHGKAHDNLMAALKQRPGKHVAVMLDTKGPEIRTGFLVDGKNVTVEKDSIVEITTD--YSIKGDATHLSCSYKDLPTSVSRDQLIYVSDGDLTFQVKEI-GETWIRCRALNTATIGETKNMNIPGAIITLPTLTESDIRDIEFPLHYHVDCIAASFIRKASDIDEIRRVLGPKLQHIQIIAKIENQEGLRNYEQILEKVDGIMVARGDLGMEMAPEKVFLAQKYMLHEATLRGRFTITATQMLDSMIKKPRPTRAECTDVANAILDGSDAVMLSGESANGLYPVKAVTMLRKLAEEAEKVYPFMRGTGGVITLESDGNDEVEDVCLDVVTHAEEVNAVAIVLVTRGNETARWTSKYHGKSPIYVFTDNDLILQIEGCYRGCISVKIEKE..................................................... 451
831 3.000e-87UniRef50_A0A0D6LTY2 Pyruvate kinase n=3 Tax=Bilateria TaxID=33213 RepID=A0A0D6LTY2_9BILA  ali  56  32......................................................................................................................................................................................GTAVNLYVDYKNIAKDLKFGVEQGVDMIFASFIRSADGVRTIKKVLGEKGKYIKIISKIENQEGMDNADEIIEESDGIMVARGDLGIEIPA------EKMLIAKCNRAGKPVICATQMLESMVKKPRPTRAEGSDVANAVLDGADCVMLSGETAKGDYPVEALKIMHYICKEAEAAIYHRKLFEELLVNTPRPTDMTQTIAIAATSAAVSCHASAILLITTTG-------------------------------RGVFPVYYDKPRHTDWPTDVDNRINHGIEIGKDRGFIHRGDFLVVITGWRQGAGFTNTLRIIT. 311
832 6.000e-87UniRef50_C5M1L6 Pyruvate kinase (Fragment) n=3 Tax=Alveolata TaxID=33630 RepID=C5M1L6_PERM5  ali  44  55..................RKTKLICTMGPSCWDVDTLVKMIDQGLNVARFSFSHGDFETHSRALRNLKDALRERPNKDVSIMLDTKGPEIRSGFFAAGGKVELEAGQDLILTTD--YSFKGDAHKIACTYEKLPQSVKPGSIILMADGTVNLEVVECYED-SVKTRVLNHAIIGERKNMNLPGVRVDLPCIGEKEANDLNWGLPNGIDFISASFVQHGDDIRELREMLGSRGRNVQIISKIESTEGLRNFDDILEASDAIMIARGDLGMEMPPEKVFLAQRMMTARCNLAGKPVITATQMLESMIENPRPTRAEVSDVANAVLDGSDGVMLSGESA.................................................................................................................................................................... 370
833 7.000e-87UniRef50_A0A061RE44 Pyruvate kinase n=1 Tax=Tetraselmis sp. GSL018 TaxID=582737 RepID=A0A061RE44_9CHLO  ali  40  209...................KTKVVCTLGPRCWSEEGIASLLDAGLDVARLNFSHGSHADHQRVLDRFRAVCGAR-GSSAAVLLDTKGPEIRTAMLRGGKDIDLAAGQEVVVAVGDEYEEATGETRIGLSYSGLCQTVRRGSKILIADGSILVAVEEVTSSTELRGRVVSGGRLGQRKNCNLPGVRVNLPMPTTQDIRDLQFACPNAVDYVAASFVQTADDIDSIRAFLDDSGQSIQIIAKIENAEGLRNFDEILHRADGIMVARGDLGMEIPSEKVALAQKMMVTKANLAGKPVICATQMLGSMVEKPTPTRAEMTDVANAVFDGVDAVMLSGETASSPYTMAAIASNAETTAGARLRLAWICDF------SRQPLSSMESLASSAVMAACDRGACGIIVASGGGHMAAAVSKFRPPVPIVVATCSMAICRRSRAVFGQVPCFVE....................................................... 643
834 2.000e-86UniRef50_D8LWK3 Pyruvate kinase n=1 Tax=Blastocystis hominis TaxID=12968 RepID=D8LWK3_BLAHO  ali  41  263..................RNTKIVCTLGPACWDVDTLVKMIDAGMNVARFNFSHGTHESHGKAHDNLMEALKQRPGKHVAVMLDTKGPEIRTGYLVDGQNITIEKDSIVEITTD--YTIKGDCHRISCSYKDLPTSVKMGQLIYVSDGDLTFQVTEIGTD-SIRCKALNTATIGQTKNMNIPGAIITLPTLTESDIRDIEFPKHYRVDCIAASFIRRGSDIDTIRRVLGPDLQYIQIIAKIENQEGLQNYAEILEKVDGIMVARGDLGMEMAPEKVFLAQKYMLHEAALRGRFTITATQMLDSMIKKPRPTRAECTDVANSILDGSDAVMLSGESANGLYPIAAVSMLRR---LSEETEKIYPAARVVRRAQKYGVGDVEAVCHGAVEQALQEHAVAIVAVTRGNELPRWISKYHAAQPIFVLT............................................................................ 668
835 2.000e-86UniRef50_A0A2N1Q725 Pyruvate kinase (Fragment) n=2 Tax=Terrabacteria group TaxID=1783272 RepID=A0A2N1Q725_9BACT  ali  46  3..................RKTKIVCTVGPSIDSPEMIGKMIDAGMNVARLNFSHANQEEHGNRIDMIRKVAK-DKKRYIGVMSDTKGPEIRTGQFENGIATKVEVLKEAVLGTRERF---------HIDCKELFDDIKVGDFILIDDGKMKLTVLEASNDRLL-CEINNSGSIRTKKGVNIPNAKLSMPFVSEKDRSDIIFSAEKNVDMIALSFVRRKEDVLEIREILKSVGKEIELIAKIENQEGVDNLESILQVSDGVMVARGDLGVEVSTELVPLYQKRIIKLANAMGKPVITATHMLESMVYSPRPTRAEASDVANAILDGSDAIMLSGESAAGEYPVEAVLTM........................................................................................................................................................ 327
836 3.000e-86UniRef50_T0RGC6 Pyruvate kinase n=2 Tax=Saprolegniaceae TaxID=4764 RepID=T0RGC6_9STRA  ali  42  62.................FRQTKIICAIGPSCWSTEMLGRLLDAGMNVARFNFSHGDHALHARSLSNLRDAMQMRPGCHCAVLLDTKGPEIRTGLLKDHTPVHLVSGQELVLVADEAFQDG-DATRIGCNYAHLATSVSPGSTILVDDGGLTLKVLACTSATQVVTQVQNSYVLDERKNMNLPGAALRIPGITTKDEHDLRFAIPQRVDIVSGSFVRSAANVRAIRACLGDAGKYIRVHAKIESLEALRNIDEIIAEADGVHVSRGDLGMELAPEQVFMAQKLIIRKANLANKPVVTSTQMLQSMTKCPTPSRAECTDVANAVLDGTDCVMLSGETAKGQYPVEAVATMARICIEAEGSI............................................................................................................................................. 403
837 3.000e-86UniRef50_A0A2G6PLK6 Pyruvate kinase n=6 Tax=root TaxID=1 RepID=A0A2G6PLK6_9BACT  ali  35  3..................KRTKVIATLGPSIDNEEKIIKAYNAGVNVIRFNFSHSNYDAQKSIINNLNNS-----GKTLSLLLDTKGPEIRTGNLENSIKYKTGDEFKM-YVSDNKLG----EKDLFCDYEYLCEDIEIGKKVIIDSGLLEVEVLEKGSDYVL-VKALNDSEIGSRRHINLPGVKLKMPGVTKKDKEDILFAIKNNFSFIAASFIRNAGNILEIRKIFEEYSENCKIISKIENEEAIDNIDEIILKSDGIMIARGDLGIEVPIEKLAVYQRDIIDKCKKYGKFVIIATHLLETMISNPFPTRAESSDVFNSILQSPDSLMLSGETAIGRFPIGAIKMMSKIITEAEKFAEY-EHKDSLDYGLNSRDIEKKLLIKSGIYIGEKLDVKCLIIFTKTGLLAKLTAGFRPRIPVYAFTNIESSVGIMNLYFGINGIFLD-----GWKSNTSSTLEKALLKLKEKGVLDNEDKAIVINDIQKNDVHIPVMEIVNV 475
838 6.000e-86UniRef50_A0A143PWK9 Pyruvate kinase n=23 Tax=unclassified Acidobacteria TaxID=458031 RepID=A0A143PWK9_9BACT  ali  40  1.................MRKTRIIATLGPSSATPDGVPALIAAGVDIFRLNFSHGSHEQHAASVALVREAAAAAARQ-VAILQDLSGPKIRTGRLASGQPIPLPAGSRLRITTGDE--EGCEGHV-YTTFAGLAHSVSPGMRLLLDDGALELRV-EATDGTSIDTTVVVGGTLAQHKGINAP--DVALPALTDKDIADLRFGASLGVDMVALSFVQTVEDLLSTRAELRAAGAEATLIAKIERPQAVANLGELLGACDGVMVARGDLGNEVPLHSVPRAQKVITQLAQRAGVPVIVATQVLESMRTNPRPTRAEVSDAANAADDSVDAIMLSGETASGLYPVAAVKLL--DAVI-----------RDAESLNPKPRAANRALCEAAVTLAHAGKAEAIVAVTREGKTARVLAALRPEIPIHAVTSDPRVARRLMLHRGIEPIAIEKS-VLDSAGGIEVERHL-----VELGVLRAGEPIV.................... 450
839 8.000e-86UniRef50_A0A2M7V3W7 Pyruvate kinase (Fragment) n=2 Tax=Candidatus Magasanikbacteria TaxID=1752731 RepID=A0A2M7V3W7_9BACT  ali  43  3..................KRTKIVCTLGPASESQDTISDMLKAGMNVARLNFSHGTHEQHAMLMTHVRTASDAL-DMPTAILQDLQGPKIRVGTL---------PEEGIVFVTFDTAQQGYEQDSIPVDYPDLHSHVSVGERMLLDDGKIEAKIVRIAN-TSISAEIIVGGTLFSHKGINVPDSGLTISALTEKDKEDAKFGVEHDVDMIALSFVTTAKDILDLRYVIKEYEKEISIIAKIERKEAVANIKEILDVADGIMVARGDLGIEMPAAEVPLIQKKLIDLSLASSKPVIVATQMLDSMQHNPRPTRAEVSDVANAVIDHADAVMLSNETATGEYPVDTVKMM--TTIIEEESSAYLHMHDDIRGGSP............................................................................................................................... 360
840 2.000e-85UniRef50_A0A0U3P8U2 Pyruvate kinase n=2 Tax=cellular organisms TaxID=131567 RepID=A0A0U3P8U2_9MOLU  ali  47  12.................VRKTKLVTTIGPSSEIPAVFPKMFENGSTCVRMNFSHGDYAEHGGRIAAAKKTNERH--LPITLLLDTKGPEIRTGNFVNDA---LDVEKGKIYKIYSKKPFIGNSEEFYIDYKQLPNDVKEGSLIYLDDGKLRLKVISTNPESCVTVQALNNHKIKNRRGVNLPGTNLSLSFLSKKDKEDLVFGCENKVHYVAASFVRNAKDVKEIRKFLNKNGNDIKIISKIECQEAVEKFDEILKLSDGIMVARGDLGIEVPFELVPNFEKTFVRKCIIARKPVIVATQMLDSMTKNPAPTRAEVTDVFWAVDLGTSATMLSGESANGDYPLEATNAMAKIALQAETEITH........................................................................................................................................... 353
841 2.000e-85UniRef50_A0A2H0S4I5 Pyruvate kinase n=2 Tax=unclassified Candidatus Peregrinibacteria TaxID=1801912 RepID=A0A2H0S4I5_9BACT  ali  38  20......LTFLMIDSDSDLTRTKVICTIGPSCWDVKIMKELADNGMNIARLNFSHGERSQHQESID---KIAEINKGRHLKVAIDTKGAEIRSGDVEKKI--VIHEGDEVVFSP--KPLPNEKRPVIIVSYDGFAKDALETKQILIDNGEIYLEIVSIEKNGTVIAKAEQGGEIGSRRHISLPGADIDLPSITEKDWDDITFGAKQNIDFIALSFIRSGAEVESVRKLLEKLKSTSKLIAKIETVKAVENIQEIIEASDAIMVARGDLGSDLPFEKLPVVQDEIVCRCKDEGKPVIIATQMLESMMEFPMPTRAEVTDTAHAVSTGTDATMLSGETAAGAHPLLVLKAMKRIHKATEQHLARLETVYDIRF-----SSKAEEEMDSAVKLAEEQHAEAIVLLSDTGRTARNIAKFRPNIPIITIVSDPVVQRHLTIVYGVYPLYIES------TASDEEMMDKGVELAMKIGLLHK......................... 475
842 2.000e-85UniRef50_A0A2G0V721 Pyruvate kinase n=1 Tax=Candidatus Tremblaya phenacola TaxID=1010676 RepID=A0A2G0V721_9PROT  ali  44  1.................MKRTKIVCTIGPSTETIKTLSKLLKEGMNIIRVNLSHGTHKEHEAKLK-AIRYILIKNIKYASVMLDSKGPEIRTMWLDNGLEVNLTIGQE--FSLVNNHNITGNKSLVAVTYKLLTKDICIGNKILIDDGLIKLVVIDKARS-IIRCRVLNNGKLGENKSINIPTINLSLPTLSEKDKKDIIFGCEQKVEYIAASFIRNLRDICIIKNLLMYKGESIKLISKIENQEGLTNFNAILKRTYGVMIARGDLGVEIPIEEVILAQKLIINKCNQAKVPVITATQMLESMVDNPRPTRAEAGDVANAILDGSDAVMLSGETAKGKHPIEAVKLMHNICIRTDNLILF........................................................................................................................................... 341
843 2.000e-85UniRef50_R5RZ77 Pyruvate kinase n=3 Tax=Bacteroidales TaxID=171549 RepID=R5RZ77_9BACE  ali  40  4..................KKTKIICTIADNRCDEGFIRQLYENGMNVVRINSAHASLEGAQMVVDNVRKVSD-----RIAILIDTKGPEVRLTQMADAVGF-VAHTDEIIEIIDNP-AEACRKGRLYTTYPHMAEDVPVGSDILIDDGSVDLSVIGKEEGK-LICKVMNEGVIKGHKSVNVPNVHINLPAVTEKDKKFIHWAIKANIDFIAHSFVRSAKDLQEIQEILDAENSHLKIISKIENQQGVDNLDDILTYCYGVMVARGDLGVEIPAERIPLVQRDIVKACRARKKPVIIATQMLQSMIENPRPTRAEVTDVANAIFQSADAIMLSGESAYGEYPVEAVKTMTKIAQQTEQTLDV--NLDDLRKVV-KPVAV--VLARSLVAATQELPVKALVFDTYTGRVGRYISTFRPEVPVYAMCYNDYTMRELSLVFGIKAYPFHK--VRDKEEFAADSIKILCDEGK----LQKGDLVGFIGGFGAQVG.......... 458
844 4.000e-85UniRef50_A0A2G6F6Q2 Pyruvate kinase n=1 Tax=bacterium DOLZORAL124_38_8 TaxID=2044884 RepID=A0A2G6F6Q2_9BACT  ali  42  1.................MRKTKIVATIGPATHSLEQLDALAKAGVGMYRLNFSHGSYDWYEGLIKDIRS---LKNGNP--IILDTKGPEIRSG----ELESPFEPGDSLVLSVADGITKS-DEKI-SVSYKKFITDVEVDDLILVDGGVMSMRILEKKGEDII-CEIVDGGTMSSRRHLNVRGRTASLDPVTEKDWEDLKFGIQHGVDMIAQSFVRSASDVKLIKDFLAENAGDIQVIAKIETCEAAQNIEEILTVADGIMVARGDLGAELPFTQVPRVQQELIEAAEKAQKPVIVATQMLETMMENPIPTRAEVTDVSLAVFQRADATMLSGETAAGKYPIKVVETMSE---ILLESESSFVESSDLRNI---PTNAVPNGLAKSVATLSQEDIDVIFVLTHTGETARDIASFRPKADIFAFTDSEITAR..................................................................... 401
845 6.000e-85UniRef50_A0A1L8I3R3 Pyruvate kinase (Fragment) n=2 Tax=Terrabacteria group TaxID=1783272 RepID=A0A1L8I3R3_9BACI  ali  47  8.........................................................................................................................DAKRVSVTYPGLAQELKPGDTVLLDDGLIELEVREI---RGLDIHCVNSGRLGNRKGVNVPGVSIGLPGITEKDAADIRFGVQQGVDFIAASFVRKPGDILEIHRILDEMQADVPVIAKIENREAVENLDAILEVADGLMVARGDLGVEIPVEEVPLLQKMIIEKCNRAGKPVITATQMLDSMQRNPRPTRAEMTDVANAILDGTDAVMLSGETASGQYPVEACRMMAKIAETTEKALDYREMFRKHRQA--GQTTITDQISQAVAGTALELKVAAIITPTESGYTARLISKYRPSCP................................................................................. 302
846 8.000e-85UniRef50_UPI000B3D43E3 pyruvate kinase isoform X2 n=1 Tax=Bombyx mori TaxID=7091 RepID=UPI000B3D43E3  ali  34  33...LDHLLNLDIKAPAGCQRTGIIANMGKSTSDVDTLEKMMSAGMNIAMLNMSYGTREEHIEMIKLLRQAAKNFSNYPLAIAARLAGKKIRTGSIADSYTVELKTGDVIRLTTDETYKDRCSTYAIYVDFMYFADQITKGDLVLIDNETIMLKV-EIISTSTVTCKIERGGMLGSYKDVFVPNVVFEMPNFSEKDKLDIDMLIHQQIDIIVASFVNSPNTIADLKDLLGVKGKKIAIIANIQTIEGFRNFDEILLTANGIMITRQELGSDITPKKLVIAQKNMIARANKANVPVCVNAHLLSSMRYKKLPLRAELLDVANCILDGADTLELSAETAVGLYPVDTVACLASACKEAEACIWSKQIFHDFVDKTPIPCDQATGVGLAAVLAAQRSLAAAIIVVTTTGKSAQIVSKYGPRCPII------------------------DAPDADWQIDLECRVNFCTKWAMDQGFVRVGDPIVVVSGWKQGAGYTNTMRI... 509
847 8.000e-85UniRef50_A0A2P4XCH6 Pyruvate kinase n=1 Tax=Phytophthora palmivora var. palmivora TaxID=611791 RepID=A0A2P4XCH6_9STRA  ali  49  11........................................................................................................................................................................NTEEIGNRKGVNLPGLIVELPALSDKDKRDLDWGVKHDIDFIAASFIRKASDVHEIRSFVADQPNYIKIISKVENLEGIQNFEEILEASDGVMCARGDLGVEVPAQKVLTYQKMMVDRCNAVGKPVIVATQMLESMQNNPRPTRAEVSDVGNAVLDGADCVMLSGESAQGKYPIESVATMNTVIKEADQLLLQ-PNYQAKFQFDP-PTSDVESAVSSAVKTANEMHAQLMIVLTRTGYTARKVAKYKPTVPVMCFTTDLKVGRQLQIHRGLYPV------VPDYLDRAPTTAE-AIAHAKKMGWLSAGDRVVVISGDK.............. 329
848 9.000e-85UniRef50_A0A2T7IUB1 Pyruvate kinase n=1 Tax=Theileria orientalis TaxID=68886 RepID=A0A2T7IUB1_THEOR  ali  42 1158..........................................SSMNICRFNFSHGNHESHSKTLAVIREAMKLVPEANIGLMLDTKGPEIRTGYLKDHTPITLEAGSTLRITTD--YSIEGNNELISCSYKKLPQSVTVGGIILIADGSLSCEVLSIGEDE-ITVKVLNNAKIGEYKNMNLPGVKVDLPILTETDKDFLNFGVPNRMNFIALSFTQTPEEIEYVRGLLGEEGKHIKIIPKIENIEGLTNYDKILDASDGIMVARGDLGMEMP-----------IEKANMKGKPIITATQMLESMS----------ADVINAVLDGSDCVMLSGETAGGRFPVQCVAIMARLCFEAENCQSMRDILAERLLNTEFQLSVPECVARSAVFLSLDVKAKMILVFSQTGRTAGLVSKYRPKCLILSISPHEHVTKALTVTRGVLSLLVES------LEDSEKNIQNCIQIATKRDLLRSGDYMVVVHGSKHNSGSSDLLKV... 1584
849 4.000e-84UniRef50_A0A1Y2CUL6 Pyruvate kinase n=1 Tax=Rhizoclosmatium globosum TaxID=329046 RepID=A0A1Y2CUL6_9FUNG  ali  37  37........ALHARAGGDVLRTKICCTIGPASYGYENIGKLVEGGMNVARLNLSHCTRETAETVVNDLRRYKETNSTAQVAVWLDINGPKIRTGKLAE---------HEVYLNAGDDFTFVNDQSIVKVSSTYTKELLKVGDKLFVDDGLLSFTVKERVANGIL-CSVDNSGYLGEFKGINMPDYVVELPTVSAKDAADIAFAMKLNVDIITVSCIRSLEDIQEVRLLLGNS--KTKVFAKIENKRGLENFEDILRTADGVVIDRGYLGCEIDVEIVTMEQKRMIMMANIMGKTVMIANQMFESMKTNPRPTRSEAADTANAVMDGADGLVLSAETAVGNYVFEALDVMRRVAAQAEKNTNYLDYQVKMTRSVPKPISVSESIASSAVLTASQVNAAIIIVITELGGTARLVAKYRPQIPVIASTLVPQTARQLASTFGLVPF-YHSGPDSNV---IQETVKFAL----ELKLVQPGQIAVITSGQSVGEGTTTQMQLYTI 516
850 7.000e-84UniRef50_A0A1F6N941 Pyruvate kinase n=2 Tax=Candidatus Magasanikbacteria TaxID=1752731 RepID=A0A1F6N941_9BACT  ali  38  2.................FKHTKIGVTVGPSCADIGTIEAMVEAGMNFARLNFAHGTYDSHAILINRLRAVEK-KTGEPLAILQDLQGPRIRIGSLRSG-GITVKTNQEVFFNTAKKKFISGE---IPVDHPELHKFLRKRQRILVDDGRIEFVVTEVNGSK-ITAKVVQEGVIHSHKGINLPDSLIKLPALSQKDRRDLRFGIKMGVDAIGLSFVSSAKDILLINEILEAEKRPIAIIAKIETKEAIKNIRSIIIASDGVMVARGDLGLELPTGEVPVIQKKIIDEANRQAKPVIVATQLLNSMQTSRRPTRAEASDVANAVIDHADALLLTNETATGVFPILAVKTMTDIIISTEKSV-----YDDIARGLPIDGAIADTVKLLS----DEVTIAAVVTATKRGLTARLLSHVRPLPMVIVGTENQDTSRQLSLSWGIKPVVMTPFPLN--TKELQERLILYIKDEK---IAKKGQKIIVVAGEPIGAEHVSTVEVRTI 478
851 7.000e-84UniRef50_R6A5W0 Pyruvate kinase n=11 Tax=Bacteroidales TaxID=171549 RepID=R6A5W0_9BACT  ali  40  3..................KKTKIVATISDMRCDVGMIQRLYDAGMNVVRLNTAHQDAVGMKRVIDNVREVSS-----HLAILVDTKGPEVRTTVT----DQPIDYHKGDIVTIVGRPEQRTTRDVIAVSYPGFVDDLHVGAQILIDDGDLGLRV-DHKEDGQLICHVENDATLGSRKSVNVPGVRINLPALTEKDKRNIEFAIDYDVAFIAHSFVRSKEDVKEVRDILDAHDSDIRIIAKIENQEGVDNIDEIIEAADGIMVARGDLGIEVPQEFIPGIQRRLVDKAIRAHKPVIVATQMLQSMIHNPRPTRTEVTDIANAVYSRADALMLSGETAYGDYPEEAVKTMATVAWQAERDT--FKEFGDVDIPLSKDPDVTEFFSKEAVMATKRMKLRAIIMDSYTGRTARYVSSFRGESTILAICYKAKTVRHLALQYGVY............................................................ 412
852 7.000e-84UniRef50_A0A1B6JP83 Pyruvate kinase (Fragment) n=5 Tax=Cicadellinae TaxID=33370 RepID=A0A1B6JP83_9HEMI  ali  32  8....................TRIACTIGPSSNNVDMLVDLMEQGMSIALVPLSLGVRQDHINMITNLRTANNQIKNRPLGIAVQTKGPGLRIGGLVKDMPVELPLHHKVTLTTDKIWRTKGTEHYIYIGFPDLCYTLKAGDVLLVGNGVVILQI-ELIDQNEAVCKVVGAGVVHSYMSVAVPDVPLRLSPLTDEDEDDLRLVATMGVDIVVATHTQNATHVKNVRRILAESGNGVKVWAQLETKEALDNLESIVEVADAIVLSRVSLTQDLPADKLFLAQKLVLGTCNKVGVPVFVTSHFLPSMQAEVTPSVSELMDVSCTVLDGVDGFILRNTTAVGKHPDHTVKTLRAVCLEAEAAVWHSQTFEYLSSHVPPPIDPTHAIAISAVEASLKSRSAAILLATTSGHSARLVARYRPRCPIIAVSRYGQVSRQLNTWRAIIPLHYVDPPLPDWTREVDVRLQFAIEFGKQQGMIKPGDPIVMMNGWRQGAG.......... 484
853 9.000e-84UniRef50_G7YA29 Pyruvate kinase n=1 Tax=Clonorchis sinensis TaxID=79923 RepID=G7YA29_CLOSI  ali  33  41.SQLEHVSQLDIVSGF-VRQATIVCTLGDRWNNDKSIESMIQGGMNILRLNMSMGSYEYYADVIRRVRAIEEASNYKPVAIAIDISAPPIRTGIINNQACVTLKDGQFVKLTINNEFQNATSDELIYLDFPCLVQCVSVGDRIHLDDGMLSLIVRDVTS-TTISCLVEQGGQLGGGKRVDLPSERLYQKTFKTTYQRDLAFACESKVDYVFTEYSFTPHQISEARSILGDK---IKLFAKVQSKESIRNLLDIISVSDGIIVGRNGLGLVYPAEKIFQLQKQIIAICNLMQKPVFVISQLLESMRFKPRATRAEISDVANAVIDGADGLILTVETSRGLFPKEAARVLHKTCREAESAI-YHEKYSDIHGLSPRSDPAYLT-ALAAVEASTTSRASAVFVATATGQSASTIAAFRPSCPVVAVVRDVQVARWCHSFRGIHPFLYLEEQLEDWSEDMDASMNAAIDYARSRRFVSGGDRVVTVTGWKAGPGATNTVRV... 543
854 1.000e-83UniRef50_A0A2E7HYJ5 Pyruvate kinase n=35 Tax=root TaxID=1 RepID=A0A2E7HYJ5_9CHLR  ali  40  4................DMRKTKIVVTIGPATDSPEVIDQLVENGMDCARLNFSHGTFESHAKIIKSVREAAQKH-NRRVAILQDLGGIKMRLGT----IDGQVQLNH------GDRVADSSDDKVIPFPQAEILKNLTKDNLIYISDGTICLEILSN-DNGVVNCRVRNGGMISSYKGLNLPGAKIDLPVLTEADKEAIKFGVEQGVDWVAVSFVRSLEDVRYAKAYMKEVGATAPMMAKLERAEAVVNVDEILSEVDAVMVARGDLGVEIDMVDVPVIQKNIVSQANQAAKVSVIATQMLRSMVVSPTPTRAEVSDISNAVLDGCDAILLSDETAVGQFPVEALTVAARTILKAEE---IYPYYQDLSE-----DSRTQAIASGAARLVKSLGAKPVVV-TNSGASARQVSRFRPDSEIAVITH........................................................................... 396
855 1.000e-83UniRef50_A0A235CR85 Pyruvate kinase n=1 Tax=Mycoplasma testudineum TaxID=244584 RepID=A0A235CR85_9MOLU  ali  42  6..................KRSKLVATIGPSSDNKEVLKKLVLNGVTCIRANFSHGDHAEQGKKFALARESEEL--NVPISTMLDTKGPEIRVGKMKDGIQTIERDSIVEIFTTREKYENEGTSKQITVEYE-MDKDLKVGNKVLIDDGKLTCEVIEI-KPGIVVVKAKNTHKVKTNKRVNLPGVEFSLPFLSEKDKTDILFGIKEKVNYVAASFVNKAENVLELRKLLDDNGEKIKIISKIESLAGCNNLDAIIEVTDGIMVARGDLGLEIPYYEVPYWEKVMIRKSRNAGKPVIVATQMLDSMENNPHPTRAEVTDVYYATELGADATMLSGESANGKFPVEAVQTMSAINQKAEQKLYYAVQLEEVRKAAPNDLRS--QVAYDLAKKTEDGTFKFAVVLSDAGRLLERVAMFRPNTAIIGMVKDP......................................................................... 415
856 1.000e-83UniRef50_UPI000B991FCE pyruvate kinase-like n=1 Tax=Nilaparvata lugens TaxID=108931 RepID=UPI000B991FCE  ali  31  27..................RLSKIICTINSRTATVEMIEKMIESGMDIARLNFAHDDAEHHLQAIANIRKAVKNIQSRSVAIAIDTKGPEIRIGMFEGEAQITLIEGKTLRLSTDRAYMKKGNSSVVYIDYEDIHEVATPGMKIFISSAILT---LDWMEENDILCSVLQGGVLTSYDEVTGEGMFKLKTELSAKDLSYIELAIQEHVDCLFLTYTMSQDSVLKVKHLIKDCGGDMLVFAKIQNKIGLMNIKEILNVADGLIVCRHDLGIEFPSEKIFCCQKMVLARCKEAGKPCICSNSSLHSMVDESVASYSECFDLGNSVLDGVDGVLLSKVTAIGRHSLESIRFTAGVCKEAESVVNHKFVFDAVS--IFHVDNPARSVAFTAVTLAFKTNAQAIIVISTSGSTAKWMSVYHPPCPIVAISRRLFDTRKLCFYRAIFPVLYKKPIENDWEEDIQERWKFGVEYCKQMQFVEAGNAVIVVTGWKIGASHTNSMKIVTV 510
857 2.000e-83UniRef50_A0A2I3LV47 Pyruvate kinase n=6 Tax=Catarrhini TaxID=9526 RepID=A0A2I3LV47_PAPAN  ali  49  4........................................................................................................................CDENILWLDYKNICKVVELGSKIYVDDGLPSLQVKQKGAD-FLVMEVENGGSSGSKKGVNLPGTAVDLLAMPE-DIQDLKFGVEQDVDMVFASFICKASDAHEVRKVLGEKGKNIKVISKIENHEGVWRFDEILETSDGLMVAHDDIGIEIPAEKVFLAQKIMIGCCNQAGRPVICATLMLESIITKPHPTRCEGSDVANAVLDRADCIMLSREAVKGDYPLEAVRMQHLIAGEAEAVTRYCP-------CT----------------------------------------------PIVAVTCNPQTVCQAHLYRSIFPVPCKDAVQETWAENEDHRVNLAMNVGNAGGFFKKGDVVIVLTSWCPGSSFTNTMRV... 325
858 2.000e-83UniRef50_UPI000B98F719 pyruvate kinase-like n=1 Tax=Nilaparvata lugens TaxID=108931 RepID=UPI000B98F719  ali  33  49..................RNTAIICTIGPASHHTQTLERLIAAGMNIARLNMAHSTHEQLVTLIKNIRAATQGYTLRSVAIAMETQGSQKRTGKLENSMDVALKKGATVTLTTNPKYKDKCNADIIYINGKK--SVLEKSEII-LDDQI--HLIVESINNEDMKCTVVNSGHLGSWKKVCFPGEDDNSSSVEIEEKKNLEFAVEQDIDIIILSHVMNAGNIFEARKCIEETGKQISLVAKLRTMSAMRNMKEIMQEVDGIMVAREELGIIFKVEKVFVALKNIITYCVRIGKPVICASVMLRSMVRCPRASQAESSDIANVVLDGVDCVVLSGETAIGNYPLESLRTMVKICNEAEDLVKLLPMDPVLSILDP-----MNTLALTAIDTALKCSAAAIMVITLSGRTAHMIARYRPDCLLIMVTRQVSTANQSHLYRRIHPILCDIQSQEDVRKDIDAQVQFGILQSKKKRLLDPGNQIVIIIGRQMDKSLMHTVRIEDV 530
859 3.000e-83UniRef50_A0A0L0G5W1 Pyruvate kinase n=3 Tax=Opisthokonta TaxID=33154 RepID=A0A0L0G5W1_9EUKA  ali  49  40............................................................................................................................................................................................................................................LIAKIENHEGLKNFDSILAESDGILVGRGHMGVEIPPEKMFLAQKMMLAKCNLAGKPSICATQMFESMTKNPRPTRAEVSDVANAVLDGADCVMLSGEISRGKYHVSAVAMMHRVCTEAESAMFYRPLFNELMDYTRKRIDTEETVAIAAVNAAYSQSAAAIICLTSSGRTAAYVSKYRPECPVLTPTRHERVTRQLHLYRSIFPMRYPHPKSEVFQDEIDSTIHWCISEAKGAGYLRANDTVIAIQGWRDGVGHTNTIRI... 301
860 5.000e-83UniRef50_Q6YQT6 Pyruvate kinase n=20 Tax=Terrabacteria group TaxID=1783272 RepID=Q6YQT6_ONYPE  ali  40  1.................MNKTKIICTLGPASYDKNILQALIQTGLNVARFNFSHAQYEQTKLLMKTIKTSDKL--DKNTGLMLDTKGPEIRTHEFDGVV--TIQKDSEVKISMTEVLGNA---KLFSVSYSNLYNELKVGDMVNIDDGYLSLEVVGKDEAKQLVTKAKNTHSIKSRRGVNVPKVNLEMDFISPKDYQDIVFAAQQDFDYIAASFVRRAQDVKDIRKILQEQGNNIQIISKIENQEGVDNLEEIIQESDGIMVARGDLGIEVDGELVPLYQTRMITKCLEYGKPVVVATQMLESMQRNPRPTKAETSDVFNAVREGTTFTMLSGESASGEYPVEAVTYMKKINYQAEKVV----NYQALSQVY-QPKNSKENLLLSAVELALRTDVKAIVVYDLKDAYN--VSKFHPSVPVLALVKTEQEARRLVLNFGVCPFVSE....................................................... 417
861 5.000e-83UniRef50_A0A2W4ICL9 Pyruvate kinase n=2 Tax=unclassified Candidatus Gracilibacteria TaxID=1046947 RepID=A0A2W4ICL9_9BACT  ali  37  1.................MKKTKIITTLGPSTDSKEKIEQLYKAGANVVRLNYSHTNYDYFSKIIDNVK---ELNKETNFAILTDTKGPEIRTKSIKESI---FIDNGEEFFLTNTKNEEKVNKKLIVCDYDYIVSDLEIGNMVDIDTGLLKAEVV-AKDKYKLVCIAKNAHLIGSKRHLNLPGTILKLPGITDSDKEDIKFAVEKGTDFIALSFVRNKENIIELKEYLKQINKGIQIISKIENKEALNNLDEIIEYSNGIMIARGDLGAEVEFESLPILQKQIAEKCKTQGKFFIVATQMLETMIEKPIPTRAELTDIYNAIVLEADCTMLSGETAAGKYPVEAVKTMAKVLRYTESELTYKHNHFEIN--SGEENEMKKQLVKSAIYTAENIKAKNIIVFSLAMT--KLISAFRPNVHIYAFTFSDEVRKKMTILFGTKTFQIEKRT-------NEQNLEKAIEVLKEKGLLSAGDKIVAV.................. 456
862 7.000e-83UniRef50_F4NRU6 Pyruvate kinase n=5 Tax=Chytridiomycota TaxID=4761 RepID=F4NRU6_BATDJ  ali  37  14...............NNVLRTKVACTIGPASRSKEVLSALVNSGMSIARINMSHSTYDNAAQIIRNLREYTDASKDHPVGIWVDINGPKVRTGKLVDGKPVHLKKGDSFLFVNDSSVIG--DHTQVSTNYTR--ELLQVGDKVFVDDGLLSFTVTERLENA---VKAVNNGILGENKGVNFPDRRIDLPAICEKDKKDILFAMQQNVDFISISCIRDIEDVEEVRMILGNS--HTKMLAKIENKRAMNNFESILNVADGIVIDRGYLGAEVDVDVICVAQKKMVALANTAGKPILIANQMLESMVSNPYPTRSEASDVTNAVMDGVDGLVLSGETAIGEYVIETVATMRKIIYQAELNTNYLEQMKAMRSVT-KPIHINESIASSAVLCARQVGAAIIMVLTEAGGTARLVAKYRPLIPVIAATTVRKTARQMSANFGLVPYYHSTGP--------ETAIRDTLLYAKDIGLCKAGDIAVITSGQVVGFLEGTTTKMQLV 486
863 1.000e-82UniRef50_A0A2G6CBF1 Pyruvate kinase n=1 Tax=candidate division SR1 bacterium TaxID=2044938 RepID=A0A2G6CBF1_9BACT  ali  39  4..................QRTKIIATVTNKFSDKK-LMQLYENGVSVVRINFSHATPESAEELINTLNKKGDTH----LAILLDTKGPDIRTG----ERDFPLVVEKKQIFKIGINQETLNPETDIFCDYQHLVKDVQVGQEIIIDSGLLKVHVVEVHDDHIF-VQADNDAEITSKRHINLPGVKIALPALINKDKEDIIFGIKMGVHFVAASFIRTGQNVKDVRKFLDQHGEHIKIISKVENQEAIENLEAIVKLSDGIMVARGDLGVEMPIQMLPVAQKSIMDTCFRYGKPVIVATELLNSMITNPFPTRAEVSDVYNSVIMRADAVMLSGETAIGKYPITSVKTMKNIILEAEKTTNNKHKDFDLQTV-DKTKLLKKAIARQALLLADEIKAKMVIVFSHTGELAAYVSSFKPNQKVVSFT----VGEENH-YRFDTSYGIVSEKIDKWTDTQRKAIAFLQEK----DTLKKDD-YVVVIGEKNYDGHQPQIRIVTI 475
864 1.000e-82UniRef50_A0A2N2F408 Pyruvate kinase n=7 Tax=Candidatus Dojkabacteria TaxID=74243 RepID=A0A2N2F408_9BACT  ali  38  3................ELAKTKIVATIGPSSWDEKILKDMIYNGMSIARINASFADFDELKRVSRSIRK---LSP--RVAVMLDTKGHKIRVTGFEKEKELK-TGDTVVILSEDTTYKEPLSDKHIAITYPNLHNEISRHAKILLDDGNILLSVEDIRGEQIL-CKIEQGGILKPKKTVNIPGTHLNFPSLSEKDEGDIKYAVKNDFDFISASFIRNVQDVAMIREAMG--NTDCKLIAKIEDREGLDNFDEILPLVDGIMIARGDMGVELPLEDVPIYQKQMIYKCRNVGKPVIVATQMLESMRENIRPTRAEVSDVANAIMDGTDAVMLSAETSTGKYPVEAVKTMNKIALRVENILKPQKVMGDTSACIE-----TDELCRSLFDMTERVMIKGIVVISVTGKTVRSLSRHRLNIPIWEIAENIKQVRQSGILRGVKTYYLNEFP-----KDRDKAVKQAVETVYSYGELDLNDKIAIISGSSIKNKSTNTI..... 462
865 2.000e-82UniRef50_A0A2W4IKL0 Pyruvate kinase n=1 Tax=candidate division SR1 bacterium TaxID=2044938 RepID=A0A2W4IKL0_9BACT  ali  39  36.................MQLTKIIATVRDDYAK-EKIPQLFDAGVDVIRLNFTHATPETAQDLMQEIQR---LNAERKLSLLLDTKGPDIRTGVR----ETPLAISKNQIFHLLVEEEKMTEESDIFCDYPGILTDVTVGQQIIIDSGLLLVEVLEVHQDR-LVLKALNDAEIGSRRHINLPGVKIGLPAMIEKDKTDILFGIKMGIAYVAASFIRTGENVKEIRAFLDKNGESVKIISKIENKEAIDNLEAIVQASDGVMIARGDLGIEMPIHELPVYQKKILDMCFVYGKPVIIATELMKSMVSNPFPTRAEVSDVYNSVMMRADAVMLSDETAVGKYPIKAVEYMAKTVKEAEKTTNNKHKDFDIQ-TTEEPEILKKALARYALMLADEIHAKLIVVFSYSGNLARYLSALKPNQPVISFT----AEESVHYSFGI-NYAIISEKIEKFGSHMSEDQEMAISILKEKKLVKKGD....................... 483
866 3.000e-82UniRef50_A0A1F8JSE2 Pyruvate kinase (Fragment) n=1 Tax=Chlamydiae bacterium RIFCSPLOWO2_01_FULL_28_7 TaxID=1797606 RepID=A0A1F8JSE2_9BACT  ali  46  19...................HTKIICTLGPSSNSLEMIIELIKTGMNVARINFSHGTHEEHFKTIQNIKEARE-KTNIPISIMLDTKGPEIRVGELKNDV---------LELKTKQKVGEAKNDDEIPINPFEVLKILKPSQKILFDDGYISAKVIEKDDDYIL-IEIQNNGILKSKKSINIPNVQLSLPAVTEQDIKDLKFGCENDIDIVAASFIRSADHVLEIKKILHQNNSDVSVIAKIESAEGVDNFDEIAEAADGIMVARGDLGVEVDLSLVPKLQKIMIHKCYDACKPVVIATQMLESMIQNPRPTRAEVSDVANAIYDSSSAVMLSAETASGKYPIETVRQM........................................................................................................................................................ 341
867 3.000e-82UniRef50_A0A0F5H0C1 Pyruvate kinase n=8 Tax=Mycoplasma TaxID=2093 RepID=A0A0F5H0C1_9MOLU  ali  39  6..................KNSKLIITIGPASSDYEIMKSLILAGATCIRANFSHGTHEEQREKFNTAKKSKEL--NIPVSLMLDTKGPEIRVGKM-QEGGQNISANSIITIKTTEEDYKNIDDKVITVSY-DMSQDLKEGDIVLFDDGKLTSHVVSV-KKGIVEVKTFNSHFLKTNKRINLPGVDFSLPFLSEKDKNDIIFGIKENVDYIAASFVNTSQNVKELRELLANNGENIKIIAKIESQTGVNNIDSIIEAVDGIMIARGDLGLEIPYYEVPVVQKMIIEKCRKAGKVVIVATQMLDSMENNPHPTRAEVTDVYLATELGADSTMLSGESASGKFPLLAVETMAKINKRAEEEFYKKENYEKAESCGTACKSNKEAFALEIASKIKNSNYKYLVVAAEGACLINALAKYKIKTPILIFGKEEFVNKFGCTY-GVWPALNSKELFQEIQKD............................................. 445
868 3.000e-82UniRef50_A0A2E3SQP6 Pyruvate kinase n=5 Tax=Bacteria TaxID=2 RepID=A0A2E3SQP6_9BACT  ali  39  2.................LKKTKIIATISDRKCDIDFLTSLYRAGMNIVRLNTAHQTPEQAEKVIRNVKAVSE-----KIAILIDTKGPEVRTA----NFKEPINLERGDIIAINGKNDPNASKERFSVSYPDYVKDVAVGNRILIDDGTIAFTVIDKKNDE-LICKVENDGVVAKNKSVNTPSVEINLPSLSQKDIEFIDFAIDNNVDFIAHSFVRKKEDLIAIQKRLDAKSSRVKLIAKIENKEGVDNIDEILEHAYGIMVARGDLAIEIPQMMIPIIQKEITNKCIRMRKPVIIATQMLHTMINNPRPTRAEVSDIANAVYDGTDAMMLSGETAYGEYALEAVNVMVETAKAIEAA------KNEAFNDIPAVVINNEILAKSSVIASTDLATKAIIADSTGGRTIRSLAAYRPDNPIYAMCYDKRLVRELALSYGVAEFI---KPVSNSDEFIRKSLNTLCEKT----LLKSSDLVVILAGNFGPSNGPSFIEISSV 465
869 4.000e-82UniRef50_A0A2J0MS70 Pyruvate kinase n=20 Tax=root TaxID=1 RepID=A0A2J0MS70_9BACT  ali  40  1.................MKQTKIVATIGPASESKEVLHKMIEAGMNVVRLNLSHGEYAWHKTIINRVRESYEL--NTPIGILADIQGPRIRT-----EVTEPIVVQKRLSDISEKEQLEAADMPTVLFDMIGIIGGVGVGHTVLIEDGAVAFVVREK-KEHCVIVEAKNDGVIKNRMGVILPDSQLVLDILSSKDKKDLHFVVEEGADFIGLSFVGTASDVESVRTVMKEMFPEKKLISKIERKEAIKNLTAIVKVSDAIMVARGDLGVEMPESEVAILQKQIIAESLRAAKPVIVATQMLQSMTENPRPTRAEVSDVSNAVIDHADAVMLSEESAMGKYPVETVAMMAEIIGKTEES----PFDDLYQTLNLNFHSEYATMLRSVYELAKSFRSKAILLLSMSGYTARLLSHFRPESKMFVATNNRNTYNELALVWGIDPYLFE....................................................... 425
870 4.000e-82UniRef50_A0A0M0K312 Pyruvate kinase n=1 Tax=Chrysochromulina sp. CCMP291 TaxID=1460289 RepID=A0A0M0K312_9EUKA  ali  39  48....................TKVVATVGPASEEFETLQKCLAAGMSVMRCNFSHATKDEFFLRTGNLRKAKG---GERINLMLDTKGPEIRMGTGNRKAKIEMVKGEMIVLSNDPALDGASDNKNLYVGYDKLTEKLVPGTKVLLDDGLISLVVKKKVDDKSVECEIINTSEIGERKGVNLPGIKTGLPALSTQDRADIAFGIQNDIDCIAASFVRSAEGVELIREYVMEYCPDPKIISKVETTEALENLQEIVDASDGVMVARGDLGVEVDIWEVTTWQKEMVRMCVEAGKPVIVATQMLESMQKNPRPTRAEVSDVTNAVLELADAVMLSGESANGLYPDGSIGMQSSIITHAEQWAREQDQY-PLYCVEPDALGSMYAVAQSAAVLAESSEAAAIVVMENGGDLARAVSACRPDMPIVPISPSMKVCRQLIVNRGVYPI---KGPVED................................................. 489
871 5.000e-82UniRef50_A0A2J0MSC3 Pyruvate kinase n=9 Tax=root TaxID=1 RepID=A0A2J0MSC3_9BACT  ali  39  4..................KRTKIVATLGPASESREILKKIIEAGVNVVRLNFSHGEHSWHGKIIDTVRESAEL--GIPVGIMADLQGPRIRTLV---DKDVEIRTGEKIIISTDFKSKSEKNSKFILLDYPGIIKDINEGNEILIEDGLKKLKVVKKEK-EFLEAEVLNGGVIKNHKGINIPDANFHFGAVTAKDEHDLEFVLGKEVDFVALSFVSNAKEIEETQEKMKKLGRDIQIIPKIERKEAIKNIDEIVAASDVVMVARGDLGIELPETEVAVHQKEIIGKCLAVGKPVIVATQMLDSMINNPIPTRAEVSDVTNAVIDHADAVMLSGESANGKYPVETVATMSEIISNTEKS-PYAPDYLD-KNILTDYASTINSAHELAKSS----GAKAIVMFSESGKTARLMAHHRPDQLLLVATNNPKTYHQLSIVWGIATYLFQ------IIDGRGRAIDLALEKAKKEERLAVGDKVVVILG................ 467
872 6.000e-82UniRef50_B0B0I0 Pyruvate kinase n=12 Tax=Candidatus Phytoplasma TaxID=33926 RepID=B0B0I0_9MOLU  ali  38  1.................MNKTKIVCTLGPACQGKEALKQLIKNGLNVARFNFSHATYENSEKILREIKENQEL--NTYVATMLDTKGPEIRTHNFVKPVQ--IEKNSEVVLGTEKKFS---------ISYKELYNDIKVNDLIFIDDGYLTLEVIQKDENRELITKAHNTHIVKSRRGVNVPNIKLKIPYISPKDASDIVFACQKGYNFLALSFVRNASDVLEVRKILKEQQNEIKIISKIENQEGIDNLEEIIKVSDGIMIARGDLGIEVAGELVPLYQTQMIQDCLYAGKPVIVATQMLESMQRNPRPTKAEISDVWNAVLEGATSTMLSGESASGLYPAQAVAFMAKINHQSEQYLDY-----EMIASFYNPKTRSEFLAFSVIQLALKEQIHAVVVDDVSYAFA--FAKMHSKVPVFVQVKDISQATSLALNFANFPFLTQEE..................................................... 419
873 7.000e-82UniRef50_R5ZEG8 Pyruvate kinase n=3 Tax=Firmicutes TaxID=1239 RepID=R5ZEG8_9CLOT  ali  36  6..................KKTKIFATIGPSSDNHDMMKALFEAGMNVIRLNFSHGDHEEQRNKIVIAQQIEK-EENQLIGVDLDTKGPEIRTGRFVGK-HVVVKKGDKIVLEMNDKLGGKQDDGLMGITYTGLIHDVNNGHHVRMDDGKLDMVVTGKDEAKVIYCEATTNDDIKDERGVNCPDTHLSMPYVSEQDRKDLIFGCEQHVNYCSASFVRDKQDIDDIRKIFNENGKQIRIISKVENTEAIRNIDDVIKYSDGLMVARGDMGVQIPAEDVPVVQMRMIKGARKLGKPIVVATQMLDSMMHSPFPTRAEVSDVANAVLSGADAVMLSGESANGDYPLESVTMQAKICARMEKELDYEKLAKEGFAMSRRQEADAMANAVVNAAYLTE--SKLIVCFSKYLESAKRLSHCRPVCPVLFETSNHDAAYDSILYWGVYPALVEKVPSSLKEMEAEA-----VALAKRYGI............................ 461
874 1.000e-81UniRef50_A0A150NID3 Pyruvate kinase n=3 Tax=Streptococcus TaxID=1301 RepID=A0A150NID3_STRMT  ali  42  13........................................................................................................................................VEVGRQVLVDDGKLGLRVV-AKDDATFEVEVENDGVIAKQKGVNIPNTKIPFPALADRDNDDIRFGLEQGINFIAISFVRTAKDVNEVRAICEETGNHVQLFAKIENQQGIDNLDEIIEAADGIMIARGDMGIEVPFEMVPVYQKMIITKVNAAGKVVITATNMLETMTEKPRATRSEVSDVFNAVIDGTDATMLSGESANGKYPLESVTTM---ATIDKNAQTLLNEYGRLNSDSFERNSKTEVMASAVKDATNSMDIKLVVTLTKTGHTARLISKYRPNADILALTFDELTERGLMLNWGVIPMLTDAPSSTDDMFEIAER------KAVEAGLVQSGDDIVIVAGVPVGAVRTNTMRIRTV 370
875 1.000e-81UniRef50_A0A2P6NUZ6 Pyruvate kinase n=1 Tax=Planoprotostelium fungivorum TaxID=1890364 RepID=A0A2P6NUZ6_9MYCE  ali  37  10.................LRRTKIVCSVGPSCEKAEVLSEMLKAGCNVFRINCSFGDYDLLRSYFQEIRKAS-AQTGLPCAILGDLQGPKFRTGETTDTIQLNVGDELDFVATKD----KGNEKKITTPNTKLVAALKENDKVL-INDGIMEIQVIKKKSDTEAVVKVVRGGELSKRKGLNVPTTEITFDDLEEKDKRDSIFLMENGVDFIGQSFVQNAGDVQRLKKHLEENKKEPKIIVKIEKPKALENYDAILAETDGVMVARGDLGVELPYIVVPVVQKVLIRKANEAEKPVILATQLLQSMMKETVPLRAEVSDVANGVFDHTDAVMTSGETTMSPHPALVVQTMEKRAPVKQVSLSHLTDVDEAR----------EAIAFAGLEAAYKSSAKAIVVFSAEGTTALRLSKGRPDCPILAVTPHESVARALRLSFAVYPIVFRSSHIEEQIAEVE-------KKVIEDGLVKRGDKVVICGGRSAPVAIRDALKIYRV 483
876 2.000e-81UniRef50_A0A150J513 Pyruvate kinase n=7 Tax=Euryarchaeota TaxID=28890 RepID=A0A150J513_9EURY  ali  39  6................NLKKTKIVCTIGPSVSNYEMLKKLVLSGMDVARLNFSHGTHSEHLKIINTIKEVSE-DTNKKIGILLDTKGPDIRIGELEKTVH--INCGNEYIFS-----VKKVKDVILQLD---ISPYLKINDKVLVDDGTLIFSVVGI-ENQEIHLRALNEGNLRPRVSINIPGDDYCPPAVTDNDILDIKFGVKNEVDFIALSFASTKVDVLKAREIIKEEKGEQWIISKIESNVGINNIDDLIEYSEGIMVARGDLGVEIDLSRIPSVQRSIIEKCNVKGRPVIVATQMLNSMIENPRPTRAEVEDIASAIYSGADAVMLSGETAIGKYPVESVEMMVKVAIETEKELKSRSEYG--------PSKRVTDVISSLVAAVLLSDAKAIVTSTRSGYTACMVARHKLSVPTYGMTNNAATARKLSIVWGINEVYLEK...................................................... 417
877 2.000e-81UniRef50_A0A0G1CJ90 Pyruvate kinase n=1 Tax=Candidatus Gottesmanbacteria bacterium GW2011_GWA1_43_11 TaxID=1618436 RepID=A0A0G1CJ90_9BACT  ali  37  13....................TKIIATIGPTCDITGQIEKLILAGVSVFRFNLKHNTQEWHNERINRIREVSERI-NQPVAVLLDLQGPEIRIGSFVEG-EIKIHTGEEIAFALN----RQPGERTIVLDNLKLLRSLRPGQRVLIDDGFLQFEITHCKKDH-VDARVVKGGIVSSHKGMNIPELSVELPVLVEKDLEHLDLAARNEVDFVALSFVRRAKDIELLRNEMQRRKLTAGIIAKIENQQALDNFVEILEIADGIMIARGDLGIEVEIFKLPFFQKEIIRKTREAGKPVITATQMLQSMVVQPIPTRAEVSDVANAIFDYTDAIMLSAETAHGEYPLESVQMMYAVAQFIENKRVALPANED----SP---SMVEAVVVSAYQTLLHQSIEAFVVLTTSGKTARLLARLRPGIPIIAVTPS-RSVRDQLLIHGIIPRIF------SFPEGAIHSFRALFQSLTKQHLVKPGDNVIVLKGWK-DTGKTNALSIETV 479
878 2.000e-81UniRef50_R7GIA4 Pyruvate kinase n=2 Tax=Clostridium TaxID=1485 RepID=R7GIA4_9CLOT  ali  39  1.................MKKTKMVCTIGPASEQKDQLEALINAGMNVMRMNFSHGDHVEQGFRIKNV-KALNAEKGWNIGIMLDTKGPEIRTGYLKNDEPVMLTEGNTIRITMD--YSYLGDANKVAISYPGLYDDISVGGRILIEDGNLTLTVTEKDENHELVCRIENSRKLKNKRNCNVPGVILNMDYIAPKDKDDIEFGCDEDVDFISASFIRRPQDIKDIRDILAAKKNDIKIISKIENQEGVSNMEEIIALSDGVMVARGDLGVDVDAWDLPAIQKEMIYLAQASGKIVVTATQMLDSMQQNPRPTRAEVSDVHNAVLDGTSATMLSGESAQGDYPLEAVTYMAKIDERAEDDIDHELMID---NVLSYPNEKNEIDAIGAVAQVANNFEVAAVVAEGDQELAFKISQYRPAADVFFATKERSDCRSLQLAWGVQP........................................................... 421
879 2.000e-81UniRef50_A0A0G1BZC0 Pyruvate kinase n=7 Tax=Bacteria candidate phyla TaxID=1783234 RepID=A0A0G1BZC0_9BACT  ali  36  5..................RLTKIVATLGPASDSPETIKKLINAGVNVFRFNTKHGTTEWHEERINRVQTAAELKAN--IGILIDLQGPEIRL-ITVDKLPFPVEKGQRVMITPS--FIPGVDS--ICIPHELVFRTVKKGDHILIDDGAIELEIISVKKDLIVAESSVE-GEIGHRKGVNFPGVEMNLPSLIHEDLKRLDMATTKRVDFVALSFSRTKKDIELLRQEMAERKIKAMIVAKIESLQALRNLDELIEATDAVMVARGDLGIEVPIEQLAYWQKTIIAKCRMANKPVITATQMLQSMTSSPRPTRAEATDVANAVLDGTDALMLSGETASGKYPVNAVAEMSKIAQYNEQTYRLI-------DFKIEPKNETDIIINSTRELLNQEKIKMILVFTRSGLTAKSVSRLRPKVPVVAMTQDQKTVELSYGVRAIRTDIHEGEFVLP---------NPAINNLVKSGELMKGDTIIVIHGYKEGSTNAVAL..... 466
880 4.000e-81UniRef50_A0A2N2LG90 Pyruvate kinase n=2 Tax=Bacteria TaxID=2 RepID=A0A2N2LG90_9BACT  ali  35  6..................HKTKIVCTIGPATDTVEMMQNLITAGMDIARLNYSHGDFEYHAGVIRKLRQAAEKV-GRSIVIMADLPGPKIRLGDLLAD-SYVLEAGESLILSSLDFVG---DQSRMSVTLPTLPMAVKPGDVIFLNDGIIQVQV-QSTTETEINCKIMVGGEIRAHKGLNIPEVNLGVHAFTPWDHECLKSALENGVDAVSQSFVDDAQDIVEVRHAVRELGHKTFIIAKIERAAAVSRLEEILAEADGIMIARGDLGVEIPIDRLALVQKQIISLANLHGKPVITATQMLESMVNNPRPTRAEATDVANAVLDGTDCIMLSEESAIGKYPIEAVKMLSKISATTEPSINVINQQTRISDFYRLDAAHITDIVSHNVFQTTQYLHPALLVAHTTGHIARMISRFK--LPIWIIAACPAVCQSLQFSWGLRPVCIAGLP-EDWENFMQQYLDRSATDAR-FAIL........................... 453
881 6.000e-81UniRef50_W0JJ25 Pyruvate kinase n=8 Tax=Bacteria TaxID=2 RepID=W0JJ25_DESAE  ali  37  8...................KTKIVCTIGPASKNREVMEKMMQNGMNIARINFAHGSFEEHKIIIEDLRKTAQKLNKR-IVILGDLPGPKIRV----EDIEIELKEGDRIVLSSNPEGNE------IGVNLENFASYLSSGTIIYLNDGFLQLRV-ESIEGQKVKCICLIGGKLSSHKGINLPGVELPLKAIGDFERKCLDFAKSVKIDAISISFAQNKQDILDAKAYCEQISYNPFIIAKIERLKAIENIDEILQETNGIMVARGDLGVETPIESIAILQKQLIQKANILGKPVITATQMLESMTNNIRPTRAESTDVANAILDGTDCVMLSEESAVGKYPAESVLMLSKIAQSVENKRYLYPIYETLFKVLSSKSPTLETMAVNVFTTVKNLNPLLLVTPTTSGATARRMSRFKLPIWILGVTHNENVAQNLEFSYGVYP-VYEQELPQDWKSYIKSLI........................................ 437
882 1.000e-80UniRef50_Q8SQP0 Pyruvate kinase n=9 Tax=Microsporidia TaxID=6029 RepID=KPYK_ENCCU  ali  41  6....................TKIVCTIGPRTSSREKIKELIDAGMSIARLNFSHGSREAHLEVIRNIRDSRS-GAGRHVSIALDTRGPEVRLRTPEMK-DIKVEGGEVLRFSEKDIWIPGVDLKSLGVDNR-----------VFIDDGAIELRVVNVEED-GFECEVLNSGMIKSNKSMNFPGTDIGDRALGDEDKNDIAFGLENGIDMVFASFVSCRADVEEIRRLVGSK---VPVVSKIESCLGMRNLKEIALCSDGVMIARGDLGVEIGLENMFSAQKRILYEVKREGRPVICATQMMESMTLKNAPNRSEISDVGNAVLDGCDCVMLSAESAVGMFPVETVKFMRSICADAER-------YD---------MESRKGAGACGVSSYVDG------VVICSGTESQIEKIYKPETPIIVISESLWILRRFSIYRGIIP........................................................... 393
883 1.000e-80UniRef50_A0A2N1Q251 Pyruvate kinase (Fragment) n=52 Tax=Bacteria TaxID=2 RepID=A0A2N1Q251_9BACT  ali  41  1.....................................................................................KGPEIRTG---------MFENGKAEFKTGDQ-VKILKEEVLHISSPELFEDIDVGDFLLIDDGKMRLTVIKSVGEFTCVVN--NSGVIKSRKGVNVPNVKLSMPFISKKDDEDIRFACHNKVDMIALSFVRRKEDVLAVREILKQENSEIELIAKIENQEGVDNINSILEVVDGIMVARGDLGVEVSTQLVPIYQKKLIQKANEVGKPVITATHMLESMMVSPRPTRAEASDVANAILDGSDAIMLSGETAAGDYPIEAVLTMDTIAKAIEDIIPYEERLQKAIKSSHQTTNDAIGIAVSQTVLTL-PKAEVIIAFTETGGTAKRMCKFRPGVPIIAITDSIETCQRLSYYWGVFATIGENVTDLRYHDEVAIKV------AKDFG-FKKGATMVITSGWGQKHGSTNTMRI... 400
884 1.000e-80UniRef50_K1ZHU4 Uncharacterized protein (Fragment) n=1 Tax=groundwater metagenome TaxID=717931 RepID=K1ZHU4_9ZZZZ  ali  43  14............VFGMPIKNTKIVCTIGPSSNEGNALIAMARAGMDLARLNLAHGDYESHGKIIDMIRDVSKKIK-RPIGIEIDLQGPKIRVGEI-KDGGILLKEGEKVTFSTDPKIAKKTKDKI-FVQYENLHKDIEKGDRIMLADGAMSAQVLEV-EERDIICKVVDGGNLTARKGMNFPDTSISVPTITEKDKNDLRFAIKRDVEWVGLSFVRSDKDIIELRELIERHGKKTKITAKIETHEGLDNFDSILEAADGIVVARGDLGPEVSITAVPEYQKMITEKSLRALKPVIVATQMLYSMTKNPRPTRAEVSDVANAVFDHVDGIYLSDETASGNFPVESVNVAREIILDAERS.............................................................................................................................................. 364
885 4.000e-80UniRef50_A0A1G1INY0 Pyruvate kinase n=1 Tax=Omnitrophica bacterium GWA2_50_21 TaxID=1801815 RepID=A0A1G1INY0_9BACT  ali  38  1.................MTRTKIICTIGPASHTKTIIKRLIQSGMNAARINFSHGSYKNNLQLIKTIR-AEAKSLNTTIPIIQDVQGPRIRLGVLPSE-GVEIKKNEVFSLTTHGAFALKKNVKYVPIGYAHLPEIMHKGEAILVEDGAIALEV-EKIADGAISVKSRANARLYSHKGINIPDTRFTRSVITKKDKEDILFGVSHHVEYIALSFAQSHKDIQKLRKFLPRGAAAPKIIAKIERPRAVQNIEKIIKASDAVMVARGDLGIETQAYKVPIIKKYIIDLCLARAKPVIVATQMLDSMIRNSRPTRAEVSDVAAAVIDHADALMLSGETASGAYPVESCRMMRD--IIAETEKS---PYDDLRYVNPKKPSLEEAIAHATRMIVKEANARAVIGIALTGTLSRMLSRFRPEVPILIAVRNEREKREVMLSWGIIPF.......................................................... 422
886 5.000e-80UniRef50_A0A1G6ENS1 Pyruvate kinase n=1 Tax=Desulfonatronum thiosulfatophilum TaxID=617002 RepID=A0A1G6ENS1_9DELT  ali  37  2...................KTKIVVTVGPAIDSEDMLRKMVEQGVRIFRLNSSHGDRAYFEKVIGRL-KALEAELDLSLSLMQDLSGPKIRIGEIP-EAPWDVYKDDQLIMRKNDYESSLKEENARWIDHPEMLEVLAAGDTVTLSDGGLQFHVTEKIDAHAVRLKAHNSGLLASKKGVAFPGKVSPLPAFTPKDRQDLAYGLELGVNVVALSFVQNAQDVESLINEMERLGHRVPVIAKLERLNAVENLQEILKLADGIMVARGDLGLECPLASLPGLQKEIIKACNQAGKPVIVATQMLLSMVENPVPTRAEITDVANAILDGTDCVMLSEESAIGNYPLATVQQMIQIGNEAEKFAA----RHNPGPIAPRDQSDPAWFLAYA-ACLLAEKARALVAHSMSGATIRHLSACRPEQPLYALSTDPLVRQFLNFSKGVLPYPV-KEQLSDHLD----RTEYFVDSCREFA............................. 449
887 1.000e-79UniRef50_A0A2M7XED7 Pyruvate kinase n=1 Tax=Candidatus Uhrbacteria bacterium CG_4_9_14_3_um_filter_41_35 TaxID=1975034 RepID=A0A2M7XED7_9BACT  ali  38  4..................KRTKILATIGPSSSSVTMLSRMIKSGLNAARLNFSHGTHEEHQQLIKNIRSASKKI-GQPIAILQDLQGPKIRLG---NLPEGGVNLVEGKLISFNTGIEKYVEGEAFPVTYKQLHKDMKAGQRILMDDGILEAECVSV-KGRVVTAKVVAGGILKSHKGINLPDSTISTSSFTNKDHEDLLFGLENGVDWVALSFVTSRVVVDQVRKLIRAKCKTLKIIAKIERAEAVQNFIDILDAVDGVMLARGDLGIEIPFEQVPIIQKEFIEICRQTGKPIVVATHMLDSMTNNPRATRAEVSDVANAIIDHADAVMLSQESATGKYPNIAVQTMAMIARETEGSRLDDINFYQIHNVQDIATSIAQTLHVMA----ENEQIDYIVTSVTYGEVAQKINVFRPSVPIVMA--CPNEARQMMIRAGIYAVVMDDNPGS.................................................. 431
888 1.000e-79UniRef50_A0A0G0C0X9 Pyruvate kinase n=1 Tax=candidate division CPR3 bacterium GW2011_GWF2_35_18 TaxID=1618350 RepID=A0A0G0C0X9_9BACT  ali  38  1.................MKKTKIVATLGPASESATKIKSLIKAGVNVFRFNLKHNDKQWHSDKIELVQKANEM--GKPIAILLDLVGRDLRLGKIPNK-GMLLKRGQEVIFADENNFKEGEIPVRNFIAYKNLKE----GVRFSADSGSLFFKVFEV-KERFFKANALKGGFLKENKGVNIPHLKVNLPALVESDLDRLSLAAKHDVDYVALSFVQTRDDIRILKREMEKLKVKAKTMAKIEDTLGIQNFDEILEEVDSIMVARGDLGIEVPIEKVPILQKEMIEKCRLAGKPVITATQMMESMLDNPIPSRADVSDVANSVYDYTDAVMLSGESAAGNYPVETVRQMSKILFQAER--KYLP------PSSPHASNTTDAMVQSALELTYFKKPSAIVVLTETGRSVRLLSRLRPILPIIALTQSEKVRDELCLTWGVTPY.......................................................... 416
889 2.000e-79UniRef50_A0A267GN27 Pyruvate kinase n=2 Tax=Macrostomum lignano TaxID=282301 RepID=A0A267GN27_9PLAT  ali  34  61....................TGIMCTIGPASWSAKVIAEMVQAGMDIARLNLCHGTLEEHRRALKLIAEAEETWQHKPLGVAVDTRGSEIRTGALPEHGKLTDTVNLETIDCSPTGAAQPITSTRLWVDFDNFAKIVQPGQAVYIDDGLLELRVESPRPDSAVDCLVIVGGQLGAARCVCLPGVDTGMPEVSQRDLDDLAALASDSIGIVMGSFVRSAETVRRLRQAATADGRPPPLVVKIGDARGLQALEEILVEADGVLVARGDLGCELPQEKVFAVQKRITAVCSTSAKASICATHLLNSMLMRPRPTRAEASDVANAVLDGVDCLMLSGETAIGKYPVEAVRTLTKICREAEASLQPGQHLQRLRRLAPAAAGPLHSSAMAACEAAVRCRAAAILVATDDAELPRLTAMFRPPCPVLCVCRDEALCRGLNMWYGLHPVLYTEPAKSEWLLEAQDRIRYAGLRVAANDILDAG........................ 541
890 2.000e-79UniRef50_UPI000675EE8C pyruvate kinase-like isoform X2 n=1 Tax=Papilio polytes TaxID=76194 RepID=UPI000675EE8C  ali  37  49..................RLTGIIATIGKSSNDVEIMQRMMAAGMNIALLNLSFGSRDEHIEAIKNLRQAAKNYSGKPLAIAARLPGRKIRTGNISDTYVEPVESGESVRLTTDETYKDRCSSSIVYIDFLHFAEQLKKGDIILLDNETIQLKV-EVISTTTLTCKIERGGMLGSNKDVFVPNVVLKMPTYSEKDKIYIEMAVHH-------------------------------------------------QVANGVMITRQELGSDISPKKLVIAQKNMIARANKANVPVCLCAHLLSSMRFNKIPLRAELLDVANCILDGADALVLSAETAIGIGPVETISCMASACKEAEACVWTKNMFQDYVEKTPMPCDQSTAIAMSAVLAAYRSLAAAIVVVTSSGTAAFQVAKYRPRCPIIAVTRYATLARQMHLYRGVMPLIYEYTPESDWQAYLEQRINFCAKWAMQRGFVRVGDPIVIVCSWKQGSEFTNTMRI... 484
891 3.000e-79UniRef50_A0A2M6WSW4 Pyruvate kinase n=1 Tax=Candidatus Falkowbacteria bacterium CG10_big_fil_rev_8_21_14_0_10_37_14 TaxID=1974561 RepID=A0A2M6WSW4_9B  ali  41  8..................KQTKIVATIASNRCEISFIKELHEAGVDVVRLNTAHQSPEESNLLIANVRKASE-----RLAIIVDTKGPEIRTLPFEDGINATVEAGQKILVRGAIKYS---DSKHLLVNYAKLVNRVIVGATLLIDDGEIALAVIGK-RNGYLVCRAESAGTIKGKKSVNIPGANLNLPSLSSKDKTFIDWAIEQKIDFIAHSFVRNAKDVLDIQKILDQKKSPIKIIAKIENQAGIDNIDRILDYAYGIMVARGDMGVEIPMEDVPAVQKELIKKCIARQKPVITATQMLHTMINNPRPTRAEVSDVANAILDGTDAVMLSGETAYGDYPVQAVKTMAQIAFDHNKALVFGEHYHD-------SNKMLTYLAKSAVKIAEELKAREIIVSDLSAFSASALAAFRPTMPIFV--KCADKCRVREL................................................................. 409
892 3.000e-79UniRef50_E0VAL8 Pyruvate kinase n=1 Tax=Pediculus humanus subsp. corporis TaxID=121224 RepID=E0VAL8_PEDHC  ali  33  15...LRQMCSLKVTSEPHFRQPAIIGTLGPACTDTSNILLLIKAGMNVARINMAHIDPCNMRDPFRNVIEANNQYIVMPISIMMDLKGPEIRTGKIDSNRIKKGSPQELYLLTVNKLFENRCTEKIIYVNYIGLLEQACDGDIIYLGDGQIKL-VVDLIENENVVCFVEKAGKLKDNQKVHVPMLPAIIPALSPFDEECLKLAIEMDVDVVVVPSARNSVVVKEIKNALKEN--KILVFSKISSCEGLENIDEILRISDGIIIQKNDLSLEISAEKMFIAQKQIIGKCNAAGKPVLCTAEFSSWFSGNVIVRRAEINDVSNAIIDGADGIILITETALGNEGVTVVSELSRVITEAEAVTMQKTFFCDL---TKELTPSVEPINAIALAAVQKIQASAILTITNSGRTAQLLSWFRPRRPIIAITRVGRVARQLNLWRAVLPLHYSGEPLDDWFQDVKSRFEYGISYGKNRGIIECGDLLVLVSGYRKKAGFTNCIRI... 518
893 4.000e-79UniRef50_A0A202DGB1 Pyruvate kinase (Fragment) n=1 Tax=archaeon D22 TaxID=1932700 RepID=A0A202DGB1_9ARCH  ali  41  1.................................................................................................................................YKGLYKEINPGNKILIDDGLLELEVIEI-KNKDIICEVKNTTKLGSTKTVSLPDVKVRIKSPTKKDWDDIEWGIKNDVDFIALSFVRNSKEVESVRKILDKSGSKIKLISKIENKEGLDNFDDILSSSDGIMIARGDLAVEIPAEEVPLLQKELIFKCNIAGKPAITATQMLESMAYNPRPTRAEINDVANAVLDGTDAVMLSGETAKGNYPMLSVKHMATACKYIEK------NSPDLIKRVHKPKFRINEFITNSVASKHLPEIKSILAPTKTGYTARKICRFKPNVPIIAFVEDVRLARQLHLSWGIYPILFDHPKT---TSELIAK---SIELSLENNLIKEEDTIIVTAGVPIQSGTTNMLEI... 361
894 4.000e-79UniRef50_A0A2E0B1A2 Pyruvate kinase n=4 Tax=Planctomycetaceae TaxID=126 RepID=A0A2E0B1A2_9PLAN  ali  36  10...................RTKTVATVGPASNSPEQLNQLIQCGVDVFRINTAHGTADEHDQIFHAIRAASE-QQGRPVAILVDLAGPKIRLGSLTETVDCPV--GRQFRFVRNE--VRAADE--LTCSYDRLIDELSVDNQVMLADGSVTMVVESVTQDQA-TCRVISGGAIRSRQGVNLPGVALSLSAVTEKDKERARWAASVGADFVSQSFVRNAEEIIALKSMLTESGSDAAVIAKIEKREALEALEPIVEAADGVMVARGDLGVEIDVAETPVAQKRIIRVCQRLCKPVIVATQMLESMHDSRRPTRAEASDVANAILDGADACMLSGETAIGQYPVDAVNMMQRIMAATERMLEERPELDDVHIITSAVVNGAGKIAEDV-------NARLVVVATRSGATARVKSKQHSLIPTIGVSASEATLRRMCLYWGITP--LRGAPVM----DPPSLRNFIASWGKEHDVVQAKDRVVFVTGTGLVAGANNLLVVHEI 476
895 5.000e-79UniRef50_A0A1F5NUN8 Pyruvate kinase n=1 Tax=Candidatus Doudnabacteria bacterium RIFCSPHIGHO2_01_FULL_46_24 TaxID=1817825 RepID=A0A1F5NUN8_9BACT  ali  40  1.................MKRTKIIATIGPASYDKDTLKQMIKSGMNAGRLNFSHGTYASHAAMIKNIRL---LSPA--VGIMQDLSGPKLRLG------EFPEKTIVENSLVILGQHGIPV--------AQPIWQWIKPGQTILIDDGLVELVATKVHED-SLEAKVIFAGTIKSHKGISLPGINVSLPTLSKKDLTDLEFGLKMGVDFVAQSFVRAASDIQAMRRAMKKFGRLVPVIAKIETPQALKNIDAIIKISDAIMVARGDLALNIAQELVPIAQKNIVHKCLQAGKPVIVATQMLDSMIRNPRPTRAEISDVANAVIDHADALMLSGESAFGKYPVKAVETMAQIINETEES-----PWDDL------PYLQKNTVLANSLLHVSRHAHAQAIVVSDLRLACDLARFRSEQELIVFVSKKDAELRQASLTWGILPLAWQ....................................................... 397
896 6.000e-79UniRef50_A0A1F7DNR7 Pyruvate kinase n=1 Tax=Candidatus Peribacteria bacterium RIFOXYD2_FULL_58_15 TaxID=1801943 RepID=A0A1F7DNR7_9BACT  ali  37  9...............SPMRRTKIVCTLGPSSATLEGIRELAKAGMNVARINLSHGKREDRLKMIEMLRKE-----GLTIAIMFDTKGAEIRTG----EVPHPIAKGQEVIFSPN----RLENEKVISVNYSGFSQDVRETNRILLDNGEMIFDIVKIADDGTVLARSQNEGEIGSRRHITLPGADIDLPSLTQQDWDDIALGIEQNVDYFSLSFIRKAEELREVRDFLMKHKSAARIITKIETKQAVANIAEIIAASDGIMVARGDLGSDLPFEDLPSIQDEIVARCHDAGVPVIVATHMLESMIEHPSPTRAEVTDVAHAAMTRADATMLSGETANGKYPLKAVEAMDR----------ILRKTEDHLQRFPLPSTDREARAEAAVSLASATSAAALLVFTKSGQTAREVSKFRPKVPVIALTNSASTLYKLCLSYGVLPLVI---PFSDP----ESTVHEGLRAALASGIVSSDQSVVLLSDMQTKDAPVQSVQTRTI 475
897 7.000e-79UniRef50_A0A2M8ENU8 Pyruvate kinase (Fragment) n=4 Tax=root TaxID=1 RepID=A0A2M8ENU8_9BACT  ali  38  3..................RRTKIIATIGPASSSVTVLTRMIKAGMNVARLNFSHGDYKEHAILMRHIRQASK-KAGQPVAILQDLQGPKIRLGVLPVE-GVNIKKGEIVKFQTGIEHYKTGG--ALPVTYDNLHKDVKTGERLFLDDGLIETEI-TAIRGKVISAKVKNGGHLSSHKGINVPDSKISTSSFTEKDHEDLLFGLENEVDWVALSFVTTPAVVMKVRDIIRAKCRALKIVVKIERQEAVERFLDILNVADGVMIARGDLGVSLRPEEVPVIQKEFVEICRQTGKPVIVATHMLQSMTDNPRATRAEVSDVANAVIDHTDATMLSGESATGKYPDVSVQTMA--AVIDEAEASRLDDFYQIHDVGDIPTAIAQTLHVMVENGQIDLIASS----STYHAVADAVNIFRPNVPIILA--CPNVARQMLLRAGIYSVVLPDDP.................................................... 428
898 8.000e-79UniRef50_A0A1F4UPJ7 Pyruvate kinase n=1 Tax=candidate division WWE3 bacterium RIFCSPHIGHO2_01_FULL_35_17 TaxID=1802614 RepID=A0A1F4UPJ7_9BACT  ali  35  3..................QKTKIIATLGPASHSSRVLEDMIIAGASVFRFNLKHNNHEWHAELANRLRGIAKKL-NKNIALLADLQGPELRIGMLPNNIDLMLSEGGEVILSKKEQ------TKTTWIPFSNISKDLEKGHSIFIDDGKIELEVVSIKQDKIIAI-VKQGGGLGSRKSVSIPQANVDVPTLMPKDKKNVAFAVKENFEFVALSFVRNAADIATLRSHIQKLGGNQSIIAKIETLKSIENMSEIVEKSDGIMVARGDLGVEVPIEKVPRIQKELILASRIHFKPVIVATQMLLSMVNNPTPSRAEVADIANSVFDKTDAIMLSEETATGLHPVKVVNTMSKIA-------RYNETHEFVDDLVLKPTSFEEIVIAASIKFSKEEDIKGYIIFTESGKSARVLSRFRPPLPIYVFSSHPSVVRKLALSYGVIHMQLHKNPVNNIKSAVE------ILKKNKF--IDKGDKLISIFGNNVGVPESN....... 464
899 1.000e-78UniRef50_A0A2E7CI26 Pyruvate kinase n=3 Tax=Proteobacteria TaxID=1224 RepID=A0A2E7CI26_9PROT  ali  36  2.................LRKTKIVATIGPATSSIENMTNILEAGVDICRVNCSHCSPEQIRSTISTIRRAAN-HLQRSVGVLLDLQGPKIRTGV----IEPPLNLNKEDVLTVDQNYKPTNDERFIGTTWPTMVNDVAVGERVLFADGALSGTVIRTKEEGTIDITMINGGELKSRKGINLPESNIKAPALTPKDEADLITGVRAGADYVALSFVRHAEDMRIIKNQLSALGQNLPVIAKIEKPQAVENIEEILDLAEGIMVARGDLGVEIPIAQVPVVQKSLIKSASKKGRLVITATQMLESMTHNPFPTRAEVTDVANAILDGSDAVMLSGETSVGVNPALTVETMSQIAIETEQGASYLP-IDQIEPLQGKYMSVVR-----AACYIARNGNRPLVVFTWSGRTAILAAKTRPKCPIFAISPNVQVVDQLRLAWGVHALLVPQ------IASTEEMIIAAEQALMESDLAKEGDEVLILGGNTPLRGASNLLKIEIV 482
900 2.000e-78UniRef50_A0A1B0FCS2 Pyruvate kinase n=2 Tax=cellular organisms TaxID=131567 RepID=A0A1B0FCS2_GLOMM  ali  40  1............................................MNVARFNFSHGLHDEQKGRIDKLKEIRTRL-NKPVAALLDTKGPEIRI-CEFADGKITLKEGQEFTLTADEIEG---NEKIVSVTYKDLYKDVKPGNSILIDDGLIGLEVKKI-KGHDIVCTVINGGVLGNKKGVNLPGVELPLPEQQPMSKRSAISSKKNGGH-------------------------DIKIIAKIENQQGVDNIDSIIEAADGIMIARGDMGVEIPLEDVPVIQKDIISKVYSAGKQVITATQMLDSMIKNPRPTRAETTDVANAIYQGTSAIMLSGETAAGKYPIEALKTMVKIARRTEADVEY--NQQFSVRIKGDTTNVTTAISHATCMTAIDLNAKAIIAVTRSGNTARMVSKYRPGCQIIACTPDERTWRQLNMIWGVAP-ILTKEEYS-----MEILLLHATEAAEENGYVKKGDVVVLTVGVPLGSGNTNLLKATVV 424
901 2.000e-78UniRef50_A0A0D2LYE6 Pyruvate kinase n=1 Tax=Monoraphidium neglectum TaxID=145388 RepID=A0A0D2LYE6_9CHLO  ali  38  1................................................................................MMLDTKGPEIRTAMLRDHKNIQIDKGQEVAYTEFEGFKEATGETVIGLSYASLCQHVKPGGRILMADGSLAIEVRKILSDTELAGVALNSKSLGERKNCNLPGVHVDLPVLGEKDVDDVQFACKFGMDLIAVSFVQSADDVKFVRKTLDDAGQGIKIISKIESWHGLINYDEILAVSDGIMIARGDLAMEVPSEKVALAQKMMTTKANIAGKFVVTATQMLESMTSNPLPTRAEMTDVANAVFDGTDAVMLSGETAGGKFPIKAVETMAAIVANAEVGVNSYQTLSFIREFTDRPMTTLEASAGCAAKSVLDVDAGLVVLASRDPAYVRYVCKYRPRVPVLVVTDSPAVARACAPTYAAVPYIADSMPSGRRTFEGEMMLERAVVWAVQAGLCPAGHEVVVIEGVDVG............ 418
902 6.000e-78UniRef50_A0A2R6KYF4 Pyruvate kinase (Fragment) n=2 Tax=Halobacteria TaxID=183963 RepID=A0A2R6KYF4_9EURY  ali  37  1.................MRNAKIVCTLGPASDSRSTIESLAEAGMSVARMNASHGSPEHRRELIDRIR-TVDTATDRPVATMLDLPGPEVRTAP----LDEPV----ELAEGSTVAFVPGDEATPERVGLSHGIGAVEAGDVVLLDDGRIETTV-ESVDGDVVRARVENGGRLGGRKGVNVPGVDLGLPVITEQDERELDVAAETEVDFVAASFVRDGEDVYRVGAELEERGVDIPVVAKIERDVAVDNLEGIVDAAYGVMVARGDLGVECPLEDVPMIQKRIIRRCHEAGVPVITATEMLDSMVHERRPTRAEASDVANAVLDGTDAVMLSGETAVGDHPVRVVETMDRIVRDVEESPEYAENLE--RRVPAADQSRTDALARSARFLARDIDATAVVAASESGYTALKAAKFRPPIPVVAST............................................................................ 395
903 7.000e-78UniRef50_A0A2N1P7J7 Pyruvate kinase n=13 Tax=root TaxID=1 RepID=A0A2N1P7J7_9BACT  ali  42  4....................TGIICTIGPSSDKDNMLGEMIEAGMNVARLNFSHGNHGDHQKRIDALGRLNRESAGN-VRIMQDLEGFRIRIGSFEDRAADTIELKEKQIVFLSNQITKHDSDTI-PLDYQGSLQVIKAGDFIYIDDGNIALRATNVTEN-SVQCEVVNPGILKEHKGVNIPDARFPFKGLAEKDRHDLEFGIKNKVDFIAQSFVRSRQDITDIRDFISKTNFSCQLIAKIENKDGIENLDEILDVADGIMVARGDLGVSLPIYEVPILQKMIIKKCEQRGKTVITATQMLESMTENLRPTRAEVSDVANAILDGSNYVMLSGETAVGKHPVETISMMKKIIDFTEQSQA--PNKD...................................................................................................................................... 344
904 8.000e-78UniRef50_E8RE76 Pyruvate kinase n=5 Tax=Desulfobulbaceae TaxID=213121 RepID=E8RE76_DESPD  ali  35  127..................KKAKIVCTIGPASNSPEMLGRMILAGMDVARLNFSHGSYEAHETTLLAVREAEKVWE-KPIAVLQDLCGPKIRTGPMREGA---IQLHAGEVLIVQKEPVEGTPERISTI-APAILADLRLGDPVLLDDGLLELRVVKEGTDE-VHCEVIVGGTLKSSKGINLPLTALSLPSVTEKDWQDLDWGLNHSIDYVALSFVRSAEDVWRIKNYIKASGKNLKVVAKIEKPEAVQNIREIVEVADAIMIARGDMGVELPAARVPRIQERIIELCWELNTPVITATQMLDSMTINARPTRAEVTDVSMAIKEGTDAVMLSQETATGVDPVNVVRTMA--SIICEEERYAHPSAEHFRELE---ADTARYPALSVVAHL--GTTSATLLLDPDGTLYPILSKWNRKTPTLVVTKSLHVARHASLYNNIFPLIIREE-----LGRTEM-VFRSLAMAREWGYIHAGETVAVVEG................ 574
905 9.000e-78UniRef50_C3YEH8 Pyruvate kinase (Fragment) n=3 Tax=Bilateria TaxID=33213 RepID=C3YEH8_BRAFL  ali  69  11........................................................................................................................................................................NGGTLGSRKGVNLPRVAVDLPAVSEKDKGDLLFGVEQGVDMVFASFIRKAADVHAVREVLGEKGKNIKIISKLENHEGVRRFDEILEASDGIMVARGDLGIEIPAEKVFIAQKMMIGRCNRIGKPVICATQMLESMIGKPRPTRAEGSDVANAVLDGADCVMLSGETAKGLYPIPSVKMM........................................................................................................................................................ 190
906 9.000e-78UniRef50_A0A0G1LYE3 Pyruvate kinase n=1 Tax=Candidatus Collierbacteria bacterium GW2011_GWB1_44_6 TaxID=1618384 RepID=A0A0G1LYE3_9BACT  ali  37  6....................TKIVATLGPASDSEETIERLIESGVNVFRFNTKHGTSQWHEERIKRVQKIADKM-GKNIGILMDLQGPEIRLETYDK---LPVRVKSGEIVRFSPSFTQG--ESSICIPHELIFKALAKGDQILIDDGAVELRVENVSND-LIEAKALDDGEIGHRKGVNLPGVAIDLPSLIQEDLKKLDLASTNRVDFVALSFSRTKKDIELLREEMEKRKFRAMIVAKIESMQALKHLDELIESSDAIMVARGDLGVEVPIEQLAYWQKIIIAKCREANKPVITATQMLQSMTGSPRPTRAEATDVANAVLDGTDAVMLSGETASGKYPVKAVQAM----------------------------SSQTDIVVNATKELLNQKIKLILVFTSSGKTARSISRLRPHVPIVSVTSDQKVVEELTLSYGV------EGHISNLNEGVFKLPNKTTDELIASGRLQKGDTIIVVHGYKEGSTNAVAL..... 445
907 1.000e-77UniRef50_A0A2H0BGJ5 Pyruvate kinase n=4 Tax=candidate division WWE3 TaxID=422282 RepID=A0A2H0BGJ5_9BACT  ali  35  1.................MAKTKIVATIGPASESEEVLRSMIIAGVDVLRFNTKHNEPEWHGEVIERARKEEEI----PVGILVDLQGPEIRINT----------PDKKPIVVRKDQFSMTGENGAVQVPTKEIYGAITVGDVVLIDDGKYMFNIVEA-DKEFFVAKSVDDYEIGNRKGMNIPGVRIDLPSLTGRDFKMLDMAEKVQPDFVALSFVRDAHDIEILRNELKQRDINSHIVSKIEGKQAVENIEHIIDLSDAVMVARGDLGIELPLEQITYWQKLIIKRCRLASKPVITATEMLQSMVENPRPTRAEVSDVSNAVFDGTDATMLSGETATGMYPLKTVQMMETIA-----------TFNEGKNFVPSETANQTRAITHAVMDIVDQSKDAVVVFTETGRTARDLSRFRPHVPIYAITEDEKTRNQLNLSYGVIPYLVS------LPDGVVLEIDKVIAVLKERGIVLSGRRVIFVHGDHWKPGLTNTITIKEI 466
908 1.000e-77UniRef50_A0A2E1JMR1 Pyruvate kinase n=24 Tax=cellular organisms TaxID=131567 RepID=A0A2E1JMR1_9GAMM  ali  38  3.................FSRTKIICTIGPATKDLKTLKNLYNNGMNVARINMSHADHRSAKSIIDRIHKINADPKSRPIGILLDTQGPEIRTGDT--NITQDLKVGDEVTLTVRDQVD--VETSSIKINYKDLIESVNPGSKISVDNGLINFKVLKK-ESETLLCKVLDGGKLGSKRHVNLPGVRINLPSITSKDMDDINFGIKNKVDFIALSFVRDKEDLKKLQQILDKKKSYAKIIAKIENQDGLDNINDICKFSWGVMVARGDLGIETSLTDLPNIQRKIMHACAKWGRRSIVATHLLESMISNPTPTRAEVSDIANAIYEGADAIMLSGETSIGKYPKECVQFLKSIAIKTEK----FPTLGYEKNLI--STTDWEHIGVAAKNLAEATNADGIIAITRTGNTATYVANAKPNIPIYTFT............................................................................ 401
909 1.000e-77UniRef50_A0A1Y1LFI1 Pyruvate kinase n=1 Tax=Photinus pyralis TaxID=7054 RepID=A0A1Y1LFI1_PHOPY  ali  30  55...............SKKRLTSIICTVDRNTHSAENFQCMMEAGMCAIRIKIGDLTHIECNDVIQTIREAIDKYSTKSLPIGIEIKGSDIRIGTLKQNFEITLTKGNPVSLTVDPGYEELVTETMIYVDYPNMIELIAPEDRIYINNGKIRLSVTEIVGDE-VKCFVETSGKLVSNCNIRFPDFPVDVPEISEQDLSDIMFAINEKIDIMFVPGMKTRESVKKLKAFLGSEGQHIMIISKIDSFQALLNVQGIVDESDGVVINRIALAIDLPEEKVFLAQKSIVGYCNKVGKPVICSSQILESLTSGAQPSSSEICDIANAVMDGIDGFLLSREISMGEDPVQAISKLSSICREAEAAVYQKQVFSELSDTAVVPLEPIYSLAISAVQVSQKCNAAAIVVLTTSGRSAKIITRFRPRCPVIAITRLGHVARQLHLYRGIDPLQYIKPTHFCWCRDADDRMQYGITWGKVNGFIRVGDAIVILAAARPGVGFTNFIQV... 543
910 2.000e-77UniRef50_B8KL75 Pyruvate kinase n=3 Tax=Gammaproteobacteria TaxID=1236 RepID=B8KL75_9GAMM  ali  37  7..................RRTKIVATIGPASESAEAIGQLLEAGVDVFRLNFSHGSIDQHAAVAERIRKQSAIH-GRYVGILADLQGPKIRISSFSSD---SIKLSVGDRFRLDSGIAEGGDQRGVGFTYLPMLDSLQSGDILLLDDGRIRLRV-DDVEKSAVDCTVIVGGKLGSRKGINRLGGGIAAPALTDKDIEDIAGLDRIAPDYVAISFVSSLADIEHAKSLLEAQNLSVAVIAKIERAEVVADDDGILKASDGVMVARGDLGVEVGDAELIGIQKDLISRARRMDRLVITATQMMESMISNSMPTRAEVFDVANAVLDGTDAVMLSAETAVGEYPVEVVKAMADAALGAERHVARTSRYRLERQF----ASAQETIAMSAIAANHYGNVRGIASLTESGTTPLLMSRLSSGLPIFALSNKPRTLSRLSLCRGVIPLYFDAS--SFEHDDIEVS---AIEYLRDNDLLSKGDSLLLTRGEVMGTGDTNIMKI... 478
911 2.000e-77UniRef50_A0A2A5ABI6 Pyruvate kinase (Fragment) n=3 Tax=Bacteria TaxID=2 RepID=A0A2A5ABI6_9GAMM  ali  41  1.................MRRTKIICTIGPATSSFDMLKALYEAGMNVVRLNMSHGDHETHLKVI-KAIKTLNQQIEFPIPILLDTQGPEIRTGHLDSDLQLNEGDSISVSVIADTSEVGS-----IHIDYQDLIQSVNVGDRITVDNGLINLEV-QSKNQFNMQCKVIDGGLLKSKRHVNLPGIRVNLPALTKKDQYDIQFAAENEVDFIALSFVRRAEDIDELRELLGSRASKIKIIAKIEDQEGLANLDAIIEKADAIMVARGDLGVEVPIAQLPNLQRKIVRQCHESGKRVIVATHLLESMIENPIPTRAEATDVANAVYEEVDAIMLSGETTVGKYPIKCI........................................................................................................................................................... 321
912 2.000e-77UniRef50_UPI00073F823A pyruvate kinase n=1 Tax=Eggerthellaceae bacterium AT8 TaxID=1720315 RepID=UPI00073F823A  ali  37  3..................KKTKIICTIGPAVDSESTLRNLIESGMDIARYNFSHGSHAAHRARMLRLKKVRREMQA-PTAIMMDISGPDIRTGRLAGNEPIRLQAGRHITLTERDVEGT---DRLVTQSHKGLWRQVEPGTSILIDDGLIELAVDEARADGDILCTVQNTGMLANHKSINLPGTPLNRPALTPKDQDDIRFGIEMGVDFICVPFARSAKDMRIVRSFLAENGADVALIAKIENAEGVDHVEEIVEASDGVVIARGDLGVEVGPERVPHVQKSIVRLCNQHRTPVIIANQMLDSMMRHPRPARADAADVANAVYDGADALMLTGETAVGKYPVPSVRMMVKIATASEPYVKANPNVEDFPTDEERCAS---MVGRSAVHTAEAIHARCLVTPTTSGRTARLISNLRPSMPIYAVTQRERVMHRMQLLWGVEPMLAAVENAS-MSETIEA.......................................... 436
913 2.000e-77UniRef50_G4VF74 Pyruvate kinase n=1 Tax=Schistosoma mansoni TaxID=6183 RepID=G4VF74_SCHMA  ali  33  627..........................LGELWDSDEKIDQMIKGGMNILRLNLSMGSKEKYAEVIRRVRSLEKSYGHNPVGIALDLSAPPVRTGLVNQSVDGIIVLQKQMVLTIDSQYEDKTTSSIIWINFPSVFQSIATGDRIYIDEGIISLIVRDVVDSISCFVEQ--GGEVGSYKRVQFPCERMYEATFNSIYKSDLEFAVQCQVDYVFTGYSTNVDHIIQAKNILG---KDILLFAKIETKNSVKNLDDIMACSDGIIIGRGSLSLCYPNEKVFQLQKQIIAKCNIFQKPVFVITHLLESMRFKPRATRAEISDVANAVLDGADGLILTVETSKGLFPKESLTVLHKICREAESTIFHERFWIDLKTARERGLSTWDPAYFACLAAVTTSNSSAIFVVTTSGRSALAIASFHPSCPVVAIMRRPEIARKCHSIRGIHPFVYTGEKLCEWSHDMDVRLNAALDFAKMRGFVGAGDQIIVVTGQKAGSGSTNTVRICEV 1106
914 2.000e-77UniRef50_UPI000D737F60 LOW QUALITY PROTEIN: pyruvate kinase PKM-like n=1 Tax=Pomacea canaliculata TaxID=400727 RepID=UPI000D737F60  ali  44  1................................................................................................................................................................................................................MIFASWVWSESIIKEIRSMLGDKGAKMKIIANIENYMGVKNFNEIVEAADGVMVARGDLGMDLPPEKVFLAQKNMIGRANVAGKPMFNVTQMLDSMVKNPRPTRAEAGDVANAILDGADCIMLSRETAAGRYPVLALKYACAIAREAEMAVHHDRVYRQLRASTPLPVDSTHCTAISAVEASIRCQASAIIVVTNSGRSAGVVARYRPPCLIVAVTKSQHTVKLLHLHRGIYPVLHDAASCGEWIDDIDFRINHALIICKRRGYVKAGVTVXLVTGSMEGPGWTNTVRTISV 296
915 2.000e-77UniRef50_A0A1F2V513 Pyruvate kinase n=5 Tax=unclassified Acidobacteria (miscellaneous) TaxID=305072 RepID=A0A1F2V513_9BACT  ali  37  1.................MRHTKIIATVGPATSEPAVLDALIAAGVDIIRLNFSHGSQSDHAFRFHQVREAAK-RADRHVAILQDLSGPKIRTGRLEGGKPIALRPGDALVIAIGDDAGRPGR---VFTTFGELAAKVSKGDRLLLDDGKIEL-VVESASAAEIQTRVIDGGELGEHKGINAPHVPLR-SGMTEKDRRDLEFGLALGVDLIALSFVQSAADITRARALIADAGRTVPIIAKLERPEAIDHLDEILAASDAVMVARGDLGLEIPLERVPRVQKEILRKARARGVPAVVATQVLESMRLEPRPTRAEASDAAGAVDGGADAIMLSGETATGLYPVRCVEVLDAIIRDAES----MPVWTD-----PGPRSTVDHMLALSEAAVMRAGAHAIVAVTREGKTAKRLSASRPQAPILAATDRADVARRLSLWRGVVPM------VCDLTGDIETVISRVVDGA................................. 434
916 6.000e-77UniRef50_C1MT92 Pyruvate kinase n=1 Tax=Micromonas pusilla (strain CCMP1545) TaxID=564608 RepID=C1MT92_MICPC  ali  40 1026...........................................................................GTNCGVLLDTKGPEIRTAMLKDHEPIELEAGQDIIV-----YAAGPEEYLTYEGYKNETETVHPGNKLLFADGSVVIEVTEILDERNLKGKVLNNKKLGERKNGNLPGVKVDLDVLQPKDVDDIKFCCKNKMDYVAVSFVQTGEDVKYVRSILDENGENVQIICKIENEEGMRNFDDILKYTDGIMVARGDLGMEIPSEKVALAQKMMITKCNIAGKFVICATQMLESMCENPLPTRGEMTDVANAVFDGADATMLSGETANGAFPDKAVATMAAIVRNAEEGVNRTQVWNFIRDFTPAPVSSIEAVTSCAAKVCIDPEISCIVCFSRGGFRGNLVSKYRPAVPIVVVTSSAASAVHTNAEYGQYAYLI-SEPGTPETESLADALKFAVDE----GLAKPGTPVAVISGTSA............. 1444
917 5.000e-58UniRef50_A0A074Z5Q7 Pyruvate kinase (Fragment) n=3 Tax=Opisthorchis viverrini TaxID=6198 RepID=A0A074Z5Q7_9TREM  ali  47  31.SHLEHVVNLDIDGETAVRNTGIICTIGPACRSVEMLQKMIESGMNIARLNFSHGTHEYHAETIKLIREAADSMTSRPVAIALDTKGPEIRTGLMFGSAEASLEVGMALRVTTDPKYADNCSEKLVYVDYPNIVHVLQVGSKIFLDDGLLSLVVRSKGPD-FLDCEVENGGKLGSRKGVNLPGAMVDLPAVSEKDKADLRFAIEHHVDIVFASFIRNPQAVIEIRELLGEAGSYIKLIAKIENHEGV............................................................................................................................................................................................................................................................. 280
918 3.000e-52UniRef50_A0A2V0PJE0 Pyruvate kinase n=1 Tax=Raphidocelis subcapitata TaxID=307507 RepID=A0A2V0PJE0_9CHLO  ali  32  706.................FRATKIVATIGPATRDAAAMASLIDAGVNVARFNVKHNTQEWRTVVAEKARANDVLSPESAMGTWVSIRGHEVRSARSGEPVAVAAGEEVVVVGLGDEEYFGSWRGGTIGISYERVGEAVKEGDTVLIDDGNLRLEVLRIEGPTRIVGRALSGHTLSELALLHLPRAHKGGPSLSPRDIEDLRLAVEFSADYVSVPFVRGAADLEQVRSVLDEAGAPLKIIAQIDCADAIAAFDEILGACDGVMVSRINLGMDIPASKVPLAQKWLIQKANLVAKPAFVAGQVMEGMATNVRPSRPEITDTVNSVYDGADGLVLMQETSTGRFAGLCVRTMAKIITDAEAGLSSSANYGFVRNFTPKPMSLLEAQASNVAKTIIDCMGSVAVVMTDRTEPVRLVAKYKPGVPLLVITTKQRVATQCSLLHGAVPVV......................................................... 1159
919 1.000e-51UniRef50_A0A061RDT8 Pyruvate kinase (Fragment) n=1 Tax=Tetraselmis sp. GSL018 TaxID=582737 RepID=A0A061RDT8_9CHLO  ali  31  158..................RLTKVVCSLGPKCWSGQGMLTLLRAGADAARLDMTVGSHSDLQEVVDQWNSACQQYPTKRHGLILHLKSPTIRTSMLWEHKRIALEEGDVVLVAVGETYAQGFKDETSATIGLSLSKIVQEGDEVLLSDGQIIIVITATPSETEVHGVCQSSKKLGERKTCNIPLAKQDTGRLWEEIGEDIQFALKNRAEYI-SVFAQTREDVQAARDLLDEGGRATKVLARVENAEALRNYDEILELADGVVISRGLLGREIRPEKVALAQKWCTTKARLAGKTVLVSDEVMESVISNPRPTRAEMTDAANSVLDGADAIVLARETSIGMFPESAVSTIGDIARDVELGLDTWQGLRWLHNLTPKPMLSLEGVAYSAVSAAVGMSACLMGITTNSIVPARLLSKYRPGIPIIVATTDPNVAAHASLIHGLFPLQLE....................................................... 603
920 3.000e-38UniRef50_A0A2J8ADH4 Pyruvate kinase (Fragment) n=1 Tax=Tetrabaena socialis TaxID=47790 RepID=A0A2J8ADH4_9CHLO  ali  37 1031...............................................................................................................................................................................HSAVPAPG---DLQALSE-------FALTNQVEFV-AVGVNNRNDVAAVRGFLDDNGGEIKLIAKIESEDSLRNLDEIIDAADAVMLARGKLGMVVTPEKVALAQSVVVTKANVAGKPVIISRQMLESMVSNPRPTRAEMTDVANAVLDGASCLMLCSETASGAFPADSLLTAASIVRNAEHATSYASMLSFIRDFSAKPFNTVEAAALALAKACMDAKLNLCVVVSDNGEAANLVSKYHPPVPLVVVSSQPPVVSQRELYFGQVGYPASEGAVMGPVGDVRGLVAEVVAFARMKGLCDSGRIKVAV.................. 1356
921 5.000e-36UniRef50_A0A0F4YIS3 Pyruvate kinase n=1 Tax=Rasamsonia emersonii CBS 393.64 TaxID=1408163 RepID=A0A0F4YIS3_TALEM  ali  50  312..........................................................................................................................................................................................................................................................................................................................................................................PRSSSPRSLCPRPADTVEAIAMAAVGASLELNAGAILVLTTSGNTARLLSKYRPACPIIMVTRNPIASRYSHLYRGVYPFLFEAKPVKIWQEDVDRRLKWGIQQGIKLGIINRGENVVCVQGWRGGMGHTNTIRV... 450
922 3.000e-31UniRef50_L5MJ90 Pyruvate kinase n=2 Tax=Laurasiatheria TaxID=314145 RepID=L5MJ90_MYODS  ali  39  557..............................................................................................................................................................................................................................................................................................................................................................IAREAEAAIYHLQLFEELRRLAPITSDPTEATAVGAVEASFKCCSGAIIVLTKSGRSAHQVARYRPRAPIIAVTRNHQTARQAHLYRGIFPVVCKDPVQDAWAEDVDLRVNLAMNVALQRDLLLQGRLYI.................... 690
923 4.000e-26UniRef50_A0A0B2VBE3 Pyruvate kinase n=2 Tax=Toxocara canis TaxID=6265 RepID=A0A0B2VBE3_TOXCA  ali  34  393........................................................................................................................................................................................................................................................................GDLIRVIPKP------------TDMAQTIAIAATSAVESCQANGIICRQWIT-LDKSFLTGTSHLMASGETAKGDYPIEALLMMHQVCREAESTVVYPKYFGDLIRVIPKPTDMAQTIAIAATSAVESCQANGIICVTNNGRAARMISHCRPAVPIYAVTCDGSVARQLHLHRGVFPLVFEGEMSDNKMDDLEKLLDYAIGVGKECGYMQSGDLLIVVTGANEGDGRTNALRI... 624
924 4.000e-25UniRef50_D8TKZ4 Pyruvate kinase n=3 Tax=Chlamydomonadales TaxID=3042 RepID=D8TKZ4_VOLCA  ali  29  1..........................................................................................................................................................................................................................................................................................................................MTDVANAVYDGVDCVMLSGESANGDFPDTAVRTMAAIVANAEVGVDYYSQYSFIRYWATKAMEPAECMLSSAASMARSTAVTLVVVLTENGRAANLISKYRPPCLVVVASTNAQVLRQASVSFGQVPLLLESLEIESEELA-----EKALEKVRSLGLLPPHDRMIVARGRHTGS........... 202
925 1.000e-18UniRef50_A0A061QIU7 Pyruvate kinase (Fragment) n=1 Tax=Tetraselmis sp. GSL018 TaxID=582737 RepID=A0A061QIU7_9CHLO  ali  34  398..................RKTKIVCTMGPKCWSEDMIGKLIDAGMNVARLNFSHGDHAAHFSVLERLRKVAA-EKSSPVACFLDTKGPEIRTAMLREDLEAGQPIVVEAVYTEFEGYKTEAETRI-GLSYAKLCQSIAPGNTILLADGTISIRVEEILSETELRGTVMNSKSLGERKNCNLPGVKVDIPVL..................................................................................................................................................................................................................................................................................................................... 575
926 2.000e-16UniRef50_D8UIN9 Pyruvate kinase n=1 Tax=Volvox carteri f. nagariensis TaxID=3068 RepID=D8UIN9_VOLCA  ali  22  676...LQITPQLIIDRISMFRSTKIIATLGPSSFAAAKLDAMLDLGVSLVRFFF----HEEYQGLLERIREQLKRRAGHPVGLMATIKGPEVRTTQLRSHAPLELSAGQQVTLVPTKGYSTPEGDHVVGIHFPALTRKLRVGDVVVLSEGAVTIKVTEV....................................................................................................................................................................................................................................................................................................................................................... 843
927 3.000e-16UniRef50_D2V449 Pyruvate kinase n=1 Tax=Naegleria gruberi TaxID=5762 RepID=D2V449_NAEGR  ali  50  18.......SQLKIPQGDYARRTKIVATIGPKTQTVEALCKLIKAGVNTIRMNFSHGSHDFHKQTVVNTRIAASQCDNAIVALMLDTKGPEIRTG....................................................................................................................................................................................................................................................................................................................................................................................................................... 103
928 6.000e-14UniRef50_A0A2J8AE03 Pyruvate kinase (Fragment) n=1 Tax=Tetrabaena socialis TaxID=47790 RepID=A0A2J8AE03_9CHLO  ali  32  207..................RKTKVVCTLGPGCWSEEGLAGLLDAGMDVARFNFSHGTHATHQEVLDRLRKVAAAKKSH-VAFLLDTKGPEIRTAMLRGGKDITLEAGQEVVVAAGEDYVKATGETKIGLSYARLCQSMKPGGIILIADGAISIEVVRILNDTEL................................................................................................................................................................................................................................................................................................................................................. 358
929 3.000e-08UniRef50_A0A0V0Y2G6 Pyruvate kinase n=1 Tax=Trichinella pseudospiralis TaxID=6337 RepID=A0A0V0Y2G6_TRIPS  ali  42  461...............................................................................................................................................................................................................................................................................................................................................................................................................................................................RDADWPTDVDKRITFGIKAGKERGFIHGGDMLVVVTGWRQGAGFTNTMRVIE. 512
FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Ye Y, Godzik A. Multiple flexible structure alignment using partial order graphs. Bioinformatics. 2005 Mar 3;