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Query: gi|16758996|ref|NP_454613.1| homoserine kinase (STY0003) [Salmonella enterica subsp. enterica serovar Typhi str. CT18], from S.typhi

Results of FFAS03 search in CSGID
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MVKVYAPASSANMSVGFDVLGAAVTPVDGTLLGDVVSVEAADHFRLHNLGRFADKLPPEPRENIVYQCWERFCQALGKTIPVAMTLEKNMPIGSGLGSSACSVVAALVAMNEHCGKPLNDTRLLALMGELEGRISGSIHYDNVAPCFLGGMQLMIEENGIISQQVPGFDEWLWVLAYPGIKVSTAEARAILPAQYRRQDCIAHGRHLAGFIHACYSRQPQLAAALMKDVIAEPYRARLLPGFSQARQAVSEIGALASGISGSGPTLFALCDKPETAQRVADWLSKHYLQNQEGFVHICRLDTAGARVVGLast
1 -85.400IDP90702 gene: thrB; homoserine kinase [Campylobacter jejuni subsp. jejuni NCTC 11168] Cj0134 [Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819]  ali follow..  23  1.MKILVPATSANLGPGFDCLGLSLKLFNET------QIQKSGVFSISIGGEGSDNIF-LKKNNIFVNIFYEIYEKLSGKDNFRFIFQNNIPLSRGLGSSSAVIVGAIASAYYMSGFKVEKECILDEALIYEN------HPDNIAPATLGGFVCSLEKNKVYSIKKEIDKDLAAVVVIPNLAMSTEQSRQALAKNLSFNDAVFNLSHASFLTACFLEKKYEFLKFASQDKLHEINRMKNLPELFEVQKFALENKALMSTLSGSGSSFFSLAFK-DDALALAKKIQTKFKD---FRVQYLEFDDNGFEIC. 292
2 -83.500IDP02093 gene: thrB; homoserine kinase [Bacillus anthracis str. `Ames Ancestor`] GBAA1970 [Bacillus anthracis str. `Ames Ancestor`]  ali follow..  25  4.LSIRVPASTANVGPGFDSVGIALSLYLHVVV-------KEKSDKWQVIHSFEDSIP-TDDKNLIVSTACKVCPSLS---PHIIEVTSNIPLTRGLGSSASAIVAGIELANQLGKLNLTIDQKVQIATNFEG------HPDNVAASILGGTVIGALDGKNVSVVRIESKELGVISLIPNEELNTDESRSVLPDVFPFHEAVKASAISNVLVAALCQKKWKVVGEMMRDHFHEPYRLELVPLLPSIRKCAKEFGAYGTALSGAGPSIFILTPY-EKRQEIAEQLARVFTS---MKVCELEIDHRGITVNK 291
3 -49.800IDP05324 putative cobalamin biosynthesis kinase [Clostridium difficile 630] CD3431 [Peptoclostridium difficile 630]  ali follow..  12  1...MKSYGI-CPASCGEFVQGIIDDEEYLC----SYAIDMYSKVYIE-----EKLVDINLGRYKSRLAIEKVFEKFNLPKNISLNINSKIPVGKGMASSTADIGATIKATLSLIDKDLSSEEISKLAAEIEPTD----------SIFIDKNSIFNPLNGTVIKYLGNLTNAKVVILEPNKVLDTMKIRLRQDYNKLKVENKEVIKKFALLEEGLKKNNLSLVGEACTLSSLANENIEKKEYLNEIIKISKKYGAYGVNIAHSGTVVGILIDKFMNDKKMIDALCESNINSVYNKIYTQNIINGGIKG.. 289
4 -47.900IDP90543 gene: ipk; 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [Vibrio cholerae O1 biovar eltor str. N16961] VC2182 [Vibrio cholerae O1 biovar El Tor str. N16961]  ali follow..  20  10TTVWPSPA---KLNLFLYITGRRANGYHDLQHGDELTITANNSGNITLSPALAD---VALEDNLIYKAAMALKNAAQSPLGADIQLHKVLPMGGGIGGGSSNAATTLVALNYLWQTGLSDDQLAEIGLALGADV----------PVFTRGFAAFAEGVGEELSAVEP-EEKWYLVVRPAVSIATKDIFTHPQLMRNTPK-----RDLASLLTTPYENDC------------EKIVRSLYPEVDKQLSWLLQYAP--SRLTGTGSCVFAEFSSRKDAQAVFAQLSDNVL..................... 268
5 -47.700IDP90649 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [Campylobacter jejuni subsp. jejuni NCTC 11168] Cj1104 [Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819]  ali follow..  15  3........AYAKANIFLKLTGFDSRKYHLLESRFILLKDVFDELELVDKESDEIISNFKCENNIIQKAYLLLSRRYNNESKKSLKLTKNIPVCAGLGGGSSDCASFLLLINETLNLKLNLQELINLSIQLGSDIAFF---------LSGFHSANVSSCGEIIEEFED-DIPNLKWTFPQISCQTKAVYDEFDRGIF--DFQKNNNQAQIYKKLSTKELLQNFKNKELNDL-FTPCATLYPKMKSY-------LQEDFFLSGSGSSVFKVDR...................................... 255
6 -47.500IDP90560 gene: ipk; 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [Yersinia pestis CO92] YPO2014 [Yersinia pestis CO92]  ali follow..  19  13.AKWPSPA---KLNLFLYITGQRADGYHQLQYGDQLTIEPRDDNQIRLLTPIAG---VENEQNLIVRAAKMLQKHPGVPRGADISIDKCLPMGGGLGGGSSNAATVLVALNLLWQCGLTDEQLADLGLTLGADV----------PVFVRGHAAFAEGIGEKLQPAEPVE-KWYLVIHPGVNIPTPIIFSDPELKRNTP----------------IRPLAALLSTPYANDC-EPIARKRFREVEQALSWLLEYAP--SRLTGTGACVFAEFDTESSARQVLSIAPEWLH..................... 273
7 -34.800IDP90942 gene: ispE; 4-diphosphocytidyl-2C-methyl-D-erythritol kinase [Vibrio cholerae 1587] A55_2372 [Vibrio cholerae O1 biovar El Tor str. N16961]  ali follow..  21  1...........................................................................................MGGGIGGGSSNAATTLVALNYLWQTGLSDDQLAEIGLALGADV----------PVFTRGFAAFAEGVGEELSAVEP-EEKWYLVVRPAVSIATKDIFTHPQLVRNTPK----------------RDLASLLATPYENDC-EKIVRSLYPEVDKQLSWLLQYAP--SRLTGTGSCVFAEFSSRKDAQAVFAQLSDNVL..................... 167
8 -28.700IDP01943 putative sugar kinase [Campylobacter jejuni subsp. jejuni NCTC 11168] Cj1425c [Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819]  ali follow..  16  3TIRTQTPLRLGLAGGGTDVLNATISLYIHCTLIKREDGKDSPDTNSYCEYESKEFLGNDGKLDIFKSIYNRIVKDFKKPLSFSLHTYSDVPSGSGLGGSSTLVVGVIKAFAEWLNLPLGEYEIAKLAYEIEREDLGIV-QDQYA-ATFGGFNFMEFYNNKRVIVNPLR-EARTVLYFTNITREAKDIEEHKKGKLGDEKSLEAMHAIKQDAEALFRADFGTLAQILGKSKKIISEIVSNDELERIYKLAIDNGAYSGKTSGAG-GFMFFFVDPTKKYNLIKALRKEQGYVQD-----FSFTKEGVKS.. 336
9 -6.960IDP01221 gene: fabD; malonyl CoA-acyl carrier protein transacylase BA_3990 [Bacillus anthracis str. Ames]  ali follow..  10.............GQGSQAVGMGKQLAENNKEVANVFAKADEVLQDSLSEVIFEGSQEKLTLTTNAQPALLTTSFAILTALKEYDITPDFVAGHSLGEYSALVAAGALTFEDAVYAVRKRGEYMEEAVP-EGYAVQIANMNSTKQIVISGTKQGVEIASQRAKENGAKRAIPLKVSGPFHSALMKPAAEKFQSVLNEITIQDTNIPVIANVTADVITSGAHIQEKLIEQLYSPVL------WYPSIEYMVNQGVDTFIEIGPGKVLAGLMKSIDSSVKAYA............................ 296
10 -6.890IDP00956 gene: fabD; acyl carrier protein S-malonyltransferase STM1194 [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]  ali follow..  10.............GQGSQSVGMLAEMAANYPIVEETFAEASAALGYDLQGPAEELNKTWQTQPALLTASVALWRVWQQQGG----KMPALMAGHSLGEYSALVCAGVINFADAVRLVEMRGKFMQEAVSIAKACEESAEGQVVSPVVIAGHKEAVERAGAACKAAGAKRALPLPVSVPSHCALMKPAADKLAVELAKITFSAPTVPVVNNVDVKCETDAAAIRDALVRQLYNPVQ------WTKSVEFIAAQGVEHLYEVGPGKVLTGLTKRIVDTLTASA............................ 296

FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Ye Y, Godzik A. Comparative analysis of protein domain organization. Genome Res. 2004 Mar;14(3):343-53.