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Query: d1z3ix2 c.37.1.19 (X:92-389) Rad54-like, Rad54L {Zebrafish (Danio rerio) [TaxId: 7955]}, from SCOP207

Results of FFAS03 search in COG1018
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst LGLRRAGVRKALHDPFEDGALVLYEPPAISAHDLIKADKEKLPVHVVVDPVLSKVLRPHQREGVKFLWDCVTGRRIENSYGCIMADEMGLGKTLQCITLIWTLLKQSPDCKPEIDKVIVVSPSSLVRNWYNEVGKWLGGRVQPVAIDGGSKDEIDSKLVNFISQQGMRIPTPILIISYETFRLHAEVLHKGKVGLVICDEGHRLKNSDNQTYLALNSMNAQRRVLISGTPIQNDLLEYFSLVHFVNSGILGTAQEFKKRFEIPILKGRDADASDKDRAAGEQKLQELISIVNRCLIRRLast
1 -49.700[KL] KOG0387 Transcription-coupled repair protein CSB/RAD26 (contains SNF2 family DNA-dependent ATPase domain)  ali follow..  25  257...................................SKKGQTFEGGFTIPGDIRPHLFRYQVTCVQWLWEL------CQEAGGIIGDEMGLGKTIQIVSFLSSLHHSGKFQ----KPALIVCPATLMKQWVNEFHTWWAPLRVVVLHATGSGQRASREKRQYELVESVFTRGHILITTYAGLRIYGDLILPREWGYCVLDEGHKIRNPDSEISISCKQIRTVNRIILSGTPIQNNLTELWNLFDFVFPGRLGTLPVFQNQFALPINIGGYANASNVQVQTAYKCACMLRDLISPYLLRR 540
2 -48.500[B] KOG0389 SNF2 family DNA-dependent ATPase  ali follow..  28  288......................................................QLADYQIIGLNWL------VMHKQEMNGILADEMGLGKTIQVIAFLAYLKENGLSQAA-----LIVVPSSTLDNWEAEISRWCPELVVEKYH-----SQDERRRMRGRFAKDGFTGFDVLLTTYHIVGSTPEMFRVCKLDYVIFDEAHMLKNMTTQRYANLITINARMRILLTGTPLQNNLLELISLLCFVMPKFFKSIEDIKSLFAKKGKSDGDQDEVSQFQE---TQIQRAKRIMKPFVLRR 519
3 -41.800[KL] COG0553 Superfamily II DNA/RNA helicases, SNF2 family  ali follow..  25  677..............................IEIQKQIRGEIEFDFQDVPQQIQATLRSYQTEGVHWL-----ERLRKMHLNGILADDMGLGKTLQAIIAVTQSKLEKGS-----GCSLIVCPTSLVYNWKEEFRKFNPE--FRTLVIDGVPSQRRKQLTAL-------ADRDVAITSYNLLQKDVELYKSFRFDYVVLDEAHHIKNRTTRNAKSVKMIQSDHRLILTGTPIENSLEELWSLFDFLMPGLLSSYDRFVGKYIRTGNYMGNK----------ADNMVALKKKVSPFILRR 915
4 -28.100[L] KOG1002 Nucleotide excision repair protein RAD16  ali follow..  21  110..........................EHMSEDVDLDQHNAVIAETAEPPSDLIMPLLRYQKEFLAWATK-----QEQSVAGGILADEMGMGKTIQAISLVLARREDRAQFGEAAGCTLVLCPLVAVSQWLNEIARFTSPGSTKVLVYHGAKRAKNIK----------FMNYDFVLTTYSTVESEYRRLHSVKWNRIILDEAHYIKERRSNTARAVFALEATYRWALSGTPLQNRVGELYSLIRFLQPNAVRHFCWWNKYVAKPITVYGSFGLGK------RAMILLKHKVLKDILLRR 482
5 -19.900[KL] COG1061 DNA or RNA helicases of superfamily II  ali follow..  22  60....................................IDEAKQFYPIDLVPSLEMEPYPHQSEALAAWKL--------AGRQGVVVLPTAAGKTYLAQLAMQAT-----------RTTLIVVPTLLMHQWYAHLVAAFPDAEVGLL-------------------GGSRDKSPVLVATYDSAAIHAEALGN-QYALIVFDECHHL--PTDFSKVIAEYAIAPYRLGLSATPERTD................................................................ 219
6 -19.600[KL] COG4646 DNA methylase  ali follow..  17  489......................................................VLYGHQKRGI---------WRIISAGSTYLAHAVGAGKTMTMAASIMEQRRLG-----LVAKAMQVVPGHCLAQAAREFLALYPTARILVA----DETNFSKDKRARFLSRAATATWDAIIITHSAFRFIG-TIAEIGVDQIIVDEAQEFRKGSQRAWDLYVKSRFIETVLASGTPITNTLGEMFSVQRLMGHPALHEFDAWASTFGDTTTELELQPSRKYKPVSRFASFVNVPELIAMF.... 794
7 -15.900[S] COG3421 Uncharacterized protein conserved in bacteria  ali follow..  9  47...............................................VERNLKYPFFEWQKSALENFVIFDFPDIKNRPTHLLFNMATGAGKTMMMAALILYYFEKG------YRHFLFFVNNNIVDKTENNFID--PAHAKFLFTEKILQGDTVIPIRKVEMFSPHSDGIEIKFTSIQKLYNDIHTERENQ--VMLGDEAHHLNAQTKGLLNKNGNPGQNVLLEFTATLPENKIITKFGLKEFLQKGYTKEINLVSSTLNKKERVLHALLFAWYRHQIALK................ 332
8 -15.700[KL] KOG1123 RNA polymerase II transcription initiation/nucleotide excision repair factor TFIIH, 3`-5` helicase subunit SSL2  ali follow..  13  315......................................NDTNNPDINIDLKPAAVLRPYQEKSLRKMFG------NGRARSGVIVLPCGAGKSLVGVTACCTV-----------KRALVLCNSGSVEQWKQQFKMWSTADDSMICRFTSEAKDKPMG-------------CGILVTTYSMIEQTMRWLQEQEWGIMVLDEVHTI--PAKMFRRVLTIVQSHCKLGLTATLLRED-ADLNFLIELQKKGYIARVQCAEVWCPMSPEFYREYLTTKTSKKMNPSKFRSCQFLIK...... 565
9 -15.500[R] COG4889 Predicted helicase  ali follow..  17  174.....................................................YSPRPHQQTAIE---KAIEGFQTHDRGKLIMA--CGTGKTFTALRLSEEVARLNGNK----ARILFLVPSQTLKEWTAQKTM--AAEDIAAYDLEVPVSTDGALIAEKLEHRKRAAGLTVVFSTYQSLPAVHAAQEAEPFDLVICDEAHRLAGEDPSNFTRISYIKAAKRLYMTATPAADHSAEVSSMDD---EAIYGPE--HRLGFGEAVEKGLLTD........................... 416
10 -13.400[V] COG3587 Restriction endonuclease  ali follow..  14  11.........................................................PHQMRAVSAVLGVFDGATPKYRTADEISMETGTGKTYTYTQTMFELHRW------GVFKFIVVVPTLSIKHFEQDFGGDYEGVRLKTYVVESAKKNKGKKSNAPITIEQFVKAENVLLINAGMVDNPVDALAAVRP-FMIVDEPHKFPTRDSAKTGNIKRLKPQYILRYGATFNDEYYNLLYR---------LTAVDAFNDGLVKGVRVFQEEMQGGMDAAVKLVSSDGKEAKFE...... 306
11 -13.100[V] COG4096 Type I site-specific restriction-modification system, R (restriction) subunit and related helicases  ali follow..  13  434..........................PEELLEMLGSEPQKQNQWFADNPGMSELGLRYYQEDAVRAVEKAIVKGQQE----ILLAMATGTGKTRTAIAMMFRLIQSQ-----RFKRILFLV-RSLGEQALGAFEDTRINGDTFNSIFDIKGLTDKFP----------EDSTKIHVATVQSLVKRTEPMPVARYDCIVVDEAH--RGYILDKEQTEGELQFRRRILLTATPALHTVQIFYTYRTAVIDGFL................................................ 665
12 -12.500[R] KOG0354 DEAD-box like helicase  ali follow..  16  73.......................................................FRDYQFNIVQ----------KALFENVLVALPTGLGKTFIAAVVMMNYLRWFPK-----SYIVFMAPTPLVTQQMEACYKITGIPKSQTAELSGHVPVTTR--------NQYYQSRNVFFVTPQTILNDIGICDRTRISCLVIDEAHRSTGNYVEVVHLLSLSNKNFRILLSATP--NKLEAIQNVIDSLHISRIEIRTENSIDISQYVQKKEVDFFPVDLSAEITDIRDRFSSILEPMLQK. 296
13 -12.200[L] COG1111 ERCC4-like helicases  ali follow..  13  16......................................................EARTYQQLLAA---------DVIRKGNSMIVAPTALGKTVVAVLVAAERLRKYRG-----SKVLILSPSPLAIQHEESFREFMLATCTSLTGSIKPEERKER------------IKSQIISATPQTVESDILRYDLRDVSLIVFDECHRAVGSYVFLASNYIQNARHPLILLTASP--ADEDKIKTVCENLFMNEVVVKTEGDPDVRPYLKPIKIEWVKVRMTPELEDIRELLRKVLKNRLKM. 238
14 -11.500[V] COG0610 Type I site-specific restriction-modification system, R (restriction) subunit and related helicases  ali follow..  12  258.......................................................MRSYQIQATREILQRMKEMEASQKEGGYIWHTTGSGKTVTSFKVAQLLASA-----PRIKNVLFIVD-------RIDLIDQTLENFKSFAYAHFKNRIKKVNGRELKRELKRKGSSQILLISVQGLTKAVKKGLENDDWNIIMDEAHRSASGESV-KLIKKALKKTTWFGFTGTPNFYSRLHTYTIKDAIGDGNVLGFDVTYFKPHWVVEHPQEDFSEKDYEKEVYQSDVYRQEVVKDILDN. 510
15 -11.200[R] COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster  ali follow..  15  22FPLNSPLFNGENNDNVSMLEQFLAQPETLLKGPYLSARKSDLPLNFFPNLTLPFPPHAHQARAFQRL-------GSDAPQPTLVATGTGSGKT----CFMFPLLNHCAGASQAGVKAIIIYPMNLATDQASRFAKTIAHGKVTVGLFVGDSEIEPSKKMSTCKHTLRESPPDILLTNYKMLRPGDQPLQPGSLRYLVVDELHTFDGAQSDLACLVRRLKHH-ACVGTSATVGDELGQ---LLDYAK-TIFDQPFT-----DDAVIREDRYTAAEYLQNYAIAYSQY............ 320
16 -10.400[LK] COG1200 RecG-like helicase  ali follow..  13  217...KHPAQQRLIFEELLAHNLAMQKVRLGTQQFSALPLHYQTDLKQRFLATLPFQPTNAQKRVVS---DIEQDLIKDYPMMRLVQGDVGSGKTLVAALAALTAIDNG--------QVALMAPTEILAE-ANNFRRWFKPFGIEVGWLAGKVKGKSRQAELEKIKTG---AVQMVVGTHALFQ---EEVEFSDLALVIIDEQHRVHQRLMLREKGEKAGFYPHQLIMTATPIPRTLA---SIIDELPPG---RAEIVMRVKNACVNEKRQAESEVLEAQAAEAIWEDLTKALPMLNI.. 520
17 -9.700[R] COG1202 Superfamily II helicase, archaea-specific  ali follow..  14  201...............................................IPESFKNVLKLEGITELLPVQVLAIKNGLLKGENLLVVSATASGKTLIGLAGIPKALEG--------KKMLFLVPLALANQKYEDFKRRYSKLGLKVAIRVGMSRIKTR---EEPVVVDTGIDADIIVGTYEGVDYLLRSGKKIGVGTVVIDEIHMIDDEEDGLIARLRKLYPKAQFILSAT-----VGNPQELARSLGMKLVLYDER---DLERHLIIARNESEKWRIIAKLCKAEVMRKSSKGFFTYSR 449
18 -9.670[T] COG1702 Phosphate starvation-inducible protein PhoH, predicted ATPase  ali follow..  12  138..................................................................................FGLGPAGSGKTYLAMAKAVQALQSK-----QVSRIILTRPAVLPGTLNEKIDPYLRPLHDAL-----------RDMVEPEVIPKLMEAGIVEVAPLAYMR------RTLNDAFVILDEAQNTTPAQMKM--FLTRLGFGSKMVVTGDITQVDVRHILRGVDDVHFSELTSSDVVRHQLVGHIVDAYEDYEEREARELKRKRQE............. 336
19 -9.090[L] COG4098 Superfamily II DNA/RNA helicase required for DNA uptake (late competence protein)  ali follow..  14  94......................................................QLTPFQEKVSEGLLQVV-----DKQKPTLVHAVTGAGKTEMIYQVVAKVINAG-------GAVCLASPIDVCLELYKRLQQDFSCGIALLHGESEPYFRTP-----------------VVATTHQLLKFYQA------FDLLIVDEVDAFPYVDNPMLYHAVKNSVKENIFLTATSTNELDKK-------VRLGELKRLNLPRRFHGNPLIIPKPIWLSDFNRYLDKNRLPKLKSYIEKQRKT. 300
20 -9.080[R] COG1201 Lhr-like helicases  ali follow..  15  24.....................................................TRPTEPQERAFPHILD---------GKHTLLIAPTGSGKTESAVLPVFNAILKKKPEKRSGISALYITPLALNRDMLSRIEVMGKLLDIKVQVRHGDTPQSERQ-------RQSRNPPDLLITTPETLQAMFSG---ETVTHVVVDEIHELASSKAQLAIGLERLVE-QRIGLSAT-----VGNPWEIAKFLAGA--ALLKLLEFDVISPQVSGEAEDREVMEIARTVGCEPEFASHLSLIR... 262
FFAS is supported by the NIH grant R01-GM087218-01
1 4 7 4 6 8   jobs submitted since Jan 1, 2011
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Rychlewski L, Zhang B, Godzik A. Functional insights from structural predictions: analysis of the Escherichia coli genome. Protein Sci. 1999 Mar;8(3):614-24.