current user: public
If you have questions about the server, please let us know.

Query: d1tf5a3 c.37.1.19 (A:1-226,A:349-395) Translocation ATPase SecA, nucleotide-binding domains {Bacillus subtilis [TaxId: 1423]}, from SCOP207

Results of FFAS03 search in H.sapiens
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
    .   10    .   20    .   30    .   40    .   50    .   60    .   70    .   80    .   90    .  100    .  110    .  120    .  130    .  140    .  150    .  160    .  170    .  180    .  190    .  200    .  210    .  220    .  230    .  240    .  250    .  260    .  270
# Score Template Links and tools%idFirst MLGILNKMFDPTKRTLNRYEKIANDIDAIRGDYENLSDDALKHKTIEFKERLEKGATTDDLLVEAFAVVREASRRVTGMFPFKVQLMGGVALHDGNIAEMKTGEGKTLTSTLPVYLNALTGKGVHVVTVNEYLASRDAEQMGKIFEFLGLTVGLNLNSMSKDEKREAYAADITYSTNNELGFDYLRDNMVLYKEQMVQRPLHFAVIDEVDSILIDEARTPLIISGQXSMTLATITFQNYFRMYEKLAGMTGTAKTEEEEFRNIYNMQVVTIPTNLast
1 -12.200sp|Q9BYX4|IFIH1_HUMAN Interferon-induced helicase C domain-containing protein 1 OS=Homo sapiens GN=IFIH1 PE=1 SV=3  ali   12  106..........................SESDTSLAEGSVSCLDESLGHNSNMGSDSGTMGSDSDEENVAARASPEPELQLRPYQMEVAQPALEGKNIIICLPTGSGKTRVAVYIAKDHL-PGKVIVLVNKVLLVEQLFRKEFQPFLKKWYRVIGLSGDTQLKISFPEVVKSCDIIISTAQILENSLLNLENGEDAGVQLSDFSLIIIDEC................................................................. 295
2 -11.900sp|Q9BYX4|IFIH1_HUMAN Interferon-induced helicase C domain-containing protein 1 OS=Homo sapiens GN=IFIH1 PE=1 SV=3  ali   13  1.......................................................................SPEPELQLRPYQMEVAQPALEGKNIIICLPTGSGKTRVAVYIAK-KASEPGKVIVLVNKVLLVEQLFRKEFQPFLKKWYRVIGLSGDTQLKISPEVVKSCDIIISTAQILENSLLNLENGEDAGVQLSDFSLIIIDECHHTNKEAVYNNIMYLMQKLKNNRLKKENKPVIPLPQILGLTAS-AKAEEHILKLANLDAFTIKT. 220
3 -11.500sp|O15315|RA51B_HUMAN DNA repair protein RAD51 homolog 2 OS=Homo sapiens GN=RAD51L1 PE=1 SV=2  ali follow..  15  20...........SRHQILTCQDFLCLSPLELMKVTGLSYRGVHELLCMVSRACAPKMQTAYGIKAQRSADFSPAFLSTTLSALDEALHGG--VACGSLTEIPPGCGKTILATLPTNMGGLEGAVVYIDTESAFSAERLVE----------IAESRFPRYFNTEEKLLLTSSKVHLYRELTC--DEVLQRIESLEEEIISKGIKLVILDSVASVV----RKEFDAQLQGNLKERNKFLAREASSLKYLA----------------EEFSIPVILTN 257
4 -11.300sp|O43542|XRCC3_HUMAN DNA repair protein XRCC3 OS=Homo sapiens GN=XRCC3 PE=1 SV=1  ali follow..  14  17...........KKAKLKSVKEVLHFSGPDLKRLTNLSSPEVWHLLRTASLHLRGSLTALQLHQQKERFPTQHQRLSLGCPVLDALLRGG--LPLDGITELRSSAGKTLAVQFPRQHGGLEAGAVYICTEDAFPHKR-------LQQLMAQQPRLRTDVPGELLQKLRFGSQIFIEHVADV--TLLECVNKKVPVLLSRGMARLVVIDSVAAPFRCEFDSQASAPRARHLQSLGATLRELSSAFQSPVLCINQVTEAMEE............... 265
5 -10.900sp|Q96C10|DHX58_HUMAN Probable ATP-dependent RNA helicase DHX58 OS=Homo sapiens GN=DHX58 PE=1 SV=1  ali   11  1............................................................................MELRSYQWEVIMPALEGKNIIIWLPTGAGKTRAAAYVAHLETVDGAKVVVLVNRVHLVTQHGEEFRRMLDGRWTVTTLSGDMGPRAGFGHLARCHDLLICTAELLQMALTSP--EEEEHVELTVFSLIVVDECHHTHKDTVYNVIMSQYLELKLQRAQPLPQVLGLTASPGTGGASKLDGAINHVLCANLDTWCIMS. 199
6 -10.800sp|Q8N8A6|DDX51_HUMAN ATP-dependent RNA helicase DDX51 OS=Homo sapiens GN=DDX51 PE=1 SV=3  ali   19  50......................................EDIPDVHPDLQKQLRAHG-----ISSYFPVQAAVIPALLESAACGFLVGRGGYRPSDLCVSAPTGSGKTLAFVIPV-VQALLSRRALVVLPTKELAQQVSKVFNIYTDATPLRVSLVTGQKSLAKEQESLVQDIVVATPGR-----LVDHI-DQTPGFSLQQLRFLIIDEADRMI............................................................. 227
7 -10.700sp|Q8IYD8|FANCM_HUMAN Fanconi anemia group M protein OS=Homo sapiens GN=FANCM PE=1 SV=2  ali   11  89............................................................................CPVRDYQLHISRA-ALFCNTLVCLPTGLGKTFIAAVVMFYRWFPSGKVVFMAPTKPLVTQQIEACYQVMGIPQSHMAEMTGSTQASTRKEIWCSKRVLFLTPQVMVNDLSRGACP------AAEIKCLVIDEVVRELVKYTNHFRILALSATPGSDIKAVQQVITLLIGQIELRSEDSPDILTYSHERKVEKLIVPLG 294
8 -10.700sp|Q9NVP1|DDX18_HUMAN ATP-dependent RNA helicase DDX18 OS=Homo sapiens GN=DDX18 PE=1 SV=2  ali   17  1.........................VEKPDNDEDESEVPSLPLGLTGAFEDTSFASLCNLVNENTLKAIKEMGFTN--MTEIQHKSIRPLLEGRDLLAAAKTGSGKTLAFLIPAV-MPRNGTGVLILSPTRELAMQTFGVLKELMTHHVHTYGLIMGGSNRSAEAQKLGNGINIIVAT------LLDHM-QNTPGFMYKNLQCLVIDEADRILLPTRRQTMLFSATQTRKVEDLA....................................... 225
9 -10.300sp|P17844|DDX5_HUMAN Probable ATP-dependent RNA helicase DDX5 OS=Homo sapiens GN=DDX5 PE=1 SV=1  ali   15  41........LVKKKWNLDELPKFEKNFYQEHPDLARRTAQEVETYRRSKEITVRGHNCPKPVLNFYEANFPANVMDVIARQNFTIQAQGWPVALSGLVGVAQTGSGKTLSYLLPAIVHINHGPICLVLAPTRELAQQVQQVAAEYCRACRLKSTCIYGGAPKGPQIRDLEVEICIATPGRL-IDFLECGKTN------LRRTTYLVLDEAD-RMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPKEVRQLAEDFLKD.................. 296
10 -10.200sp|Q9UPY3|DICER_HUMAN Endoribonuclease Dicer OS=Homo sapiens GN=DICER1 PE=1 SV=3  ali   13  1...................................MKSPALQPLSMAGLQLMTPASSPMGPFFGLPWQQEAIHDNIYTPRKYQVELL--AALDHNTIVCLNTGSGKTFIAVLLTK-FSRNGKRTVFLVNSANQVA---QQVSAVRTHSDLKVGEYSNLETKERWNQEFTKHQVLIMTCYVALNVLKNGYLS------LSDINLLVFDEIMKLCENCPSCPRILGLTASILNGKCDPEELEEKIQKLEKILKSNAETATDLVVL........... 243
11 -10.100sp|Q8TDG4|HELQ_HUMAN Helicase POLQ-like OS=Homo sapiens GN=HELQ PE=1 SV=2  ali   12  19.............................................................LPSKVRDLYAQFKGIEKLYEWQHTCLTLNSVQERKIYSLPTSGGKTLVAEILMLQELLCCRKDVLMIL-VAIVQEKISGLSSFGIELGFFVEEYAGSKGRFPPTKRREKKSLYIATIEKGHSLVNSLIETGRIDSL----GLVVVDELH-MIGEGSRGATL--------EMTLAKILYTSKTTQIIGMSATNVEDLQKFLQAEYYTSQFRPV. 222
12 -9.900sp|P19447|ERCC3_HUMAN TFIIH basal transcription factor complex helicase XPB subunit OS=Homo sapiens GN=ERCC3 PE=1 SV=1  ali   13  166..............................................................................LRPYQEKSLRKMFGNRSGVIVLPCGAGKSLVGV---TAACTVRKRCLVLGNSAVSVE---QWKAQFKMWSTIDDSQI-CRFTSDAKDKPIGCSVAISTYSMLGHTTKRSWEAERVMEWLKQEWGLMILDEVHTI.............................................................. 296
13 -9.880sp|Q9GZR7|DDX24_HUMAN ATP-dependent RNA helicase DDX24 OS=Homo sapiens GN=DDX24 PE=1 SV=1  ali   15  5...............................ESEALPSDIAAEARAKTGGTVSDQALLFGDDDAGEGPSSLIREKPVPK------QNEN---EEENLDKEQTGNLKQELDDKSATCKAYPKRPLLVLTPTRELAVQVKQHIDAVARFTGIKTAILVGGMSTQKQQRMLNREIVVATPGRL-WELIKEKHYHLRN---LRQLRCLVVDEADRMV............................................................. 177
14 -9.870sp|Q13206|DDX10_HUMAN Probable ATP-dependent RNA helicase DDX10 OS=Homo sapiens GN=DDX10 PE=1 SV=2  ali   19  54..............................SRLMQNYEKINVNEITRFSDFPLSKKTLKGLQEAQYRLVTEIQKQTIGLALQGKDVLGA----------AKTGSGKTLAFLVPVL-TSTDGLGVLIISPTRELAYQTFEVLRKVGKNHDFSAGLIIGGKDLKHEAERINNNILVCTPGRL-------QHMDETVSFHATDLQMLVLDEADRILLPKKRQTLLFSATQTKSVKDLA....................................... 264
15 -9.840sp|O95786|DDX58_HUMAN Probable ATP-dependent RNA helicase DDX58 OS=Homo sapiens GN=DDX58 PE=1 SV=2  ali   9  44.............................DVETEDLEDKMETSDIQIFYQEDPECQNLSENSCPPSEVSDTNLYSPFKPRNYQLELALPAMKGKNTIICAPTGCGKTFVSLLICE-QGQKGKVVFFANQIPVYEQQKSVFSKYFERHGYRVTGISGATAENVPVEQIVENNDIIILTPQILVNNLKKGTIPS-----LSIFTLMIFDECHNTSKQHPYNMIM------FNYLDQKLGGSSGPLPQVIGLTASVGVGDAKNTDEALDYICKLCAS 283
16 -9.810sp|Q86XP3|DDX42_HUMAN ATP-dependent RNA helicase DDX42 OS=Homo sapiens GN=DDX42 PE=1 SV=1  ali   16  59.................DYPPFEKNFYNEHEEITNLTPQQLIDLRHKLNLRVSGAAPPRPGSSFAHFGFDEQLMHQIRKSEYTIQCQGVPVALSGRIGIAKTGSGKTAAFIWPMLIHIMDGPIAVIVCPTRELCQQIHAECKRFGKAYNLRSVAVYGGGSMWEQAKALQAEIVVCTPGRL-IDHVKKKATN------LQRVSYLVFDEAD-RMFDMGFEYQVRSIASHVRPDRQTLLFSATFRKKIEKLA........................ 299
17 -9.720sp|Q8IY21|DDX60_HUMAN Probable ATP-dependent RNA helicase DDX60 OS=Homo sapiens GN=DDX60 PE=2 SV=3  ali   12  143.........................................................MGHYLIRDERKDPDPRVQDFIPDTWQRELLDVVDKNESAVIVAPTSSGKTYASCMEKVLKESDDGVVVYVAPTKALVNQVAATVQNRFTKNLPSGEVLCGVFTREYRHDALNCQVLITVPACFEI------LLAPHRQNWVKKIRYVIFDEV---CLGGEI........................................................ 298
18 -9.600sp|Q7L014|DDX46_HUMAN Probable ATP-dependent RNA helicase DDX46 OS=Homo sapiens GN=DDX46 PE=1 SV=2  ali   15  27.................EYEPFRKNFYVEVPELAKMSQEEVNVFRLEMEGITVKGKGCPKPIKS--MKILNSLKKHGYEKPTPIQTQAIPAIMSGRIGIAKTGSGKTIAFLLPMFRHIMDQRSLEIMTPTRELALQITKECKKFSKTLGLRVVCVYGGTGISEQIAELKRGAEIIVCTP-----MIDMLAANSGRVTLRRVTYVVLDEADRMFVRPDRQTVMFSATFPRAMEALARRILSKPIEVQVGGRSVVCSDVEQQVIV........... 299
19 -9.550sp|Q9BUQ8|DDX23_HUMAN Probable ATP-dependent RNA helicase DDX23 OS=Homo sapiens GN=DDX23 PE=1 SV=3  ali   15  42............KLRKKEAKQRWDDRHWSQKKLDEMTDRDWRIFREDYSITTKGGKIPNPIRSWKDSSLPPHILEVIDKCGYKIQRQAIPIGLQNRIGVAETGSGKTAAFLIPLLVWITTGPYAIILAPTRELAQQIEEETIKFGKPLGIRTVAVIGGISREDQGFRLRCEIVIATPGRL-IDVLENRYLV------LSRCTYVVLDEADRMI............................................................. 255
20 -9.430sp|Q92841|DDX17_HUMAN Probable ATP-dependent RNA helicase DDX17 OS=Homo sapiens GN=DDX17 PE=1 SV=1  ali   15  38........LRKKKWDLSELPKFEKNFYVEHPEVARLTPYEVDELRRKKEITVRGGDVCPKPVFAFHHAVMDVLMDQHFTEPTPIQCQGFPLALSGRVGIAQTGSGKTLAYLLPAIVHINHGPICLVLAPTRELAQQVQQVADDYGKCSRLKSTCIYGGAPKGPQIRDLEVEICIATPGRL-IDFLESGKTN------LRRCTYLVLDEAD-RMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPKEVRQLAEDFLRD.................. 294
21 -9.330sp|Q8N3C0|HELC1_HUMAN Activating signal cointegrator 1 complex subunit 3 OS=Homo sapiens GN=ASCC3 PE=1 SV=3  ali   18  91.....................ILPERHPPHTELLDLQPLPITALGCKAYEALYNFSHFNPVQTQIFHTLYHTDCNVL----------------------APTGSGKTVAAELAVFNKYPTSKAVYIAPLKALVRERMDDWKVRIEEKLGKKVIELTGDVT-PDMKSIAKADLIVTTPEKW------DGVSRSWQNRYVQQVTILIIDEIH--LLGEERGPVIVSRTNFISSHTEKPVRIVGLSTALANARDLA..................... 300
22 -9.290sp|Q5T1V6|DDX59_HUMAN Probable ATP-dependent RNA helicase DDX59 OS=Homo sapiens GN=DDX59 PE=1 SV=1  ali   15  9.................ESPLNASYVYKEHPFILNLQEDQIENLKQQLGILVQGQEVTRPIIDFEHCSLPEVLNHNLKKSGYEIQMQMIPVGLLGRLASADTGSGKTAAFLLPVIMRALKTPSALILTPTRELAIQIERQAKELMSGLRMKTVLLVGGLPLPPQLYRLQVKVIIATPGRL-LDIIKQSSVE------LCGVKIVVVDEADTMLIPNDCQTILVSATIPTSIEQLASQLLHNPVRIITGEKNLPCANVRQIILW........... 273
23 -9.100sp|P19447|ERCC3_HUMAN TFIIH basal transcription factor complex helicase XPB subunit OS=Homo sapiens GN=ERCC3 PE=1 SV=1  ali   14  16..............................................................................LRPYQEKSLRKMFGNGRAVIVLPCGAGKSLVG---VTAACTVRKRCLVLGNSAVSVEQWKAQFKMWSTIDDSQICRFTSD----AKDKPIGCSVAISTYSMLGHTTKRSWEAERVMEWLKQEWGLMILDEV................................................................. 143
24 -9.090sp|Q15477|SKIV2_HUMAN Helicase SKI2W OS=Homo sapiens GN=SKIV2L PE=1 SV=3  ali   13  105.......................SSLEDLVLKEASTAVSTPEAPEPPSQEQWAIPVDATSPVGDFYRLIPQPAFQ-FEPDVFQKQAILHLERHDSVFVAAHTSAGKTVVAEYAIALAQKHMTRTIYTSPIKALSNQKFRDFRNTFGDVGLLTGDVQLHPEAS-----------------MTTEILRSMLYSGSD--VIRDLEWVIFDEVH--INDVER........................................................ 283
25 -9.040sp|Q06609|RAD51_HUMAN DNA repair protein RAD51 homolog 1 OS=Homo sapiens GN=RAD51 PE=1 SV=1  ali follow..  19  42...........EEAGFHTVEAVAYAPKKELINIKGISEAKADKILAEAAKLVPMGFTTAT---EFHQRRSEIIQITTGSKELDKLLQGG--IETGSITEMEFRTGKTVTCQLPIDRGGGEGKAMYIDTEGTFRPER----LLAVAERYGLSGSDVLD---------------NVAYARAFNTDHQTQLLYQASAMMVESRYALLIVDSATALYRTD------YSGRGELSARQMHLARFLRMLLRLA----------------DEFGVAVVITN 267
FFAS is supported by the NIH grant R01-GM087218-01
1 4 7 6 0 7   jobs submitted since Jan 1, 2011
Comments and questions to: webmaster
Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Li W, Pio F, Pawlowski K, Godzik A. Saturated BLAST: an automated multiple intermediate sequence search used to detect distant homology. Bioinformatics. 2000 Dec;16(12):1105-10.