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Query: d1z63a1 c.37.1.19 (A:432-661) Helicase of the SNF2/Rad54 hamily {Sulfolobus solfataricus [TaxId: 2287]}, from SCOP207

Results of FFAS03 search in PDB1018
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst FQLLEPYNIKANLRPYQIKGFSWMRFMNKLGFGICLADDMGLGKTLQTIAVFSDAKKENELTPSLVICPLSVLKNWEEELSKFAPHLRFAVFHEDRSKIKLEDYDIILTTYAVLLRDTRLKEVEWKYIVIDEAQNIKNPQTKIFKAVKELKSKYRIALTGTPIENKVDDLWSIMTFLNPGLLGSYSEFKSKFATPIKKGDNMAKEELKAIISPFILRRTKYDKAIINDLPLast
1 -96.4001z63_A mol:protein length:500 Helicase of the snf2/rad54 family  ali model follow..  100  21.QLLEPYNIKANLRPYQIKGFSWMRFMNKLGFGICLADDMGLGKTLQTIAVFSDAKKENELTPSLVICPLSVLKNWEEELSKFAPHLRFAVFHEDRSKIKLEDYDIILTTYAVLLRDTRLKEVEWKYIVIDEAQNIKNPQTKIFKAVKELKSKYRIALTGTPIENKVDDLWSIMTFLNPGLLGSYSEFKSKFATPIKKGDNMAKEELKAIISPFILRRTKYDKAIINDLP 249
2 -61.6001z3i_X mol:protein length:644 similar to RAD54-like  ali model follow..  27  44VHVVVDPVLSKVLRPHQREGVKFLWDCIENSYGCIMADEMGLGKTLQCITLIWTLLKQSPIDKVIVVSPSSLVRNWYNEVGKWLGGRVQPVAIDGGSKDEIDPTPILIISYETFRLHAELHKGKVGLVICDEGHRLKNSDNQTYLALNSMNAQRRVLISGTPIQNDLLEYFSLVHFVNSGILGTAQEFKKRFEIPILKGRDQKLQELISIVNRCLIRRTSDI--LSKYLP 308
3 -58.9005jxr_A mol:protein length:723 Chromatin-remodeling complex ATPase-like protein  ali model follow..  33  97...ESPPFIQGTMRDYQIAGLNWLISLHENGISGILADEMGLGKTLQTIAFLGYLRHIMGIGPHLVTVPKSTLDNWKREFEKWTPEVNVLVLQGAKEERHQENFDVCITSYEMILREKALKKFAWEYIIIDEAHRIKNEESSLAQVIRMFNSRNRLLITGTPLQNNLHELWALLNFLLPDVFGDSEAFDQWFSGQ-DRDQDTVVQQLHRVLRPFLLRRVKSD--VEKSLL 330
4 -57.9005x0x_O mol:protein length:735 Transcription regulatory protein SNF2  ali model follow..  36  100..........GTLKDYQIKGLQWMVSLFNNHLNGILADEMGLGKTIQTISLLTYLEMKNIRGPYLVIVPLSTLSNWSSEFAKWAPTLRTISFKGSPNERKAGEFDVVLTTFEYIIKERALSKVKWVHMIIDEGHRMKNAQSKLSLTLNTYHADYRLILTGTPLQNNLPELWALLNFVLPKIFNSVKSFDEWFNTPFEEETLLVIRRLHKVLRPFLLRRLKKD--VEKELP 339
5 -53.2005hzr_A mol:protein length:732 SNF2-family ATP dependent chromatin remodeling factor like protein  ali model follow..  34  108..........GTLKEYQLKGLQWMLSLYNNNLNGILADEMGLGKTIQTISLITYLEKKHQQGPYLVIVPLSTLTNWNLEFDKWAPSVAKVVYKGPPNARKMGKFQVLLTTYEYIIKDRPLSKIKWFHMIIDEGHRMKNANSKLSATIQQYSTRFRLILTGTPLQNNLAELWAMLNFVLPNIFKSAKTFDEWFNTPFEEEQILVIRRLHKVLRPFLLRRLKKD--VEKDLP 347
6 -51.5005vvr_M mol:protein length:1085 DNA repair and recombination protein RAD26  ali model follow..  37  286.QFKIPGEIYSLLFNYQKTCVQWLYELYQQNCGGIIGDEMGLGKTIQVIAFIAALHHSGLLGPVLIVCPATVMKQWCNEFQHWWPPLRTVILHSMGSGMASTDGHILITTYVGLRIHSDLLKVKWQYAVLDEGHKIRNPDSEISLTCKKLKTHNRIILSGTPIQNNLTELWSLFDFIFPGKLGTLPVFQQQFVIPINIGGYANAVALRDLISPYLLRRVKAD--VAKDLP 578
7 -49.7006etx_G mol:protein length:1290 DNA helicase INO80  ali model follow..  32  241.DIPQPTIFNGKLKGYQLKGMNWLANLYEQGINGILADEMGLGKTVQSIALLAHLAERENIGPFLIISPASTLNNWHQEFTRFVPKFKVLPYWGNPHDRKVAPFHVVITSYQLVVQDVKFQRVKWQYMVLDEAQALKSSSSVRWKILLQFQCRNRLLLTGTPIQNTMAELWALLHFIMPTLFDSHEEFNEWFSKDIESHDENQLSRLHMILKPFMLRRIKKD--VENELS 490
8 -46.8006ftx_W mol:protein length:878 Chromatin-remodeling ATPase  ali model follow..  30  192..........GELRDFQLTGINWMAFLWSKGDNGILADEMGLGKTVQTVAFISWLFARRQNGPHIIVVPLSTMPAWLDTFEKWAPDLNCICYMGNQKSRDT-KFNVLLTTYEYILKDRALGSIKWQFMAVDEAHRLKNAESSLYESLNSFKVANRMLITGTPLQNNIKELAALVNFLMPGRFNQDEEQEEYI------------HDLHRRIQPFILRRLKKD--VEKSLP 416
9 -42.6006fml_G mol:protein length:1856 Ino80  ali model follow..  32  961.EVAQPKLLNCQLKEYQLKGLNWLVNLYEQGINGILADEMGLGKTVQSISVMAYLAERYDIGPFLVVAPASTLHNWQQEVSKFVPDFKVLPYWGTAADRKVSPFHVMITSYQLVVSDVAFQKMKWQYMILDEAQAIKSSQSSRWKCLLGFHCRNRLLLTGTPIQNNMQELWALLHFIMPSLFDSHDEFSEWFSKDIESHNEDQLKRLHMILKPFMLRRVKKH--VQKELG 1211
10 -40.9004s20_K mol:protein length:974 RNA polymerase-associated protein RapA  ali model follow..  16  143.PYSGLRGQRTSLIPHQLNIAHDV--GRRHAPRVLLADEVGLGKTIEAGMILHQQLLSGAAERVLIIVPETLQHQWLVEMRRFNLRFALFDDERYAEAQHFDTEQLVICSLDFARRSKQLCEAEWDLLVVDEAHHLVWSEDAPSREYQAIEVPGVLLLTATPEQLGMESHFARLRLLDPNRFHDFAQFVEEQKNYCPVADNDELNMLGEMIGEQDIEPLLQAANSDSE.. 394
11 -40.4005o9g_W mol:protein length:1468 Chromo domain-containing protein 1  ali model follow..  31  366...VQPPFIKGELRDFQLTGINWMAFLWSKGDNGILADEMGLGKTVQTVAFISWLFARRQNGPHIIVVPLSTMPAWLDTFEKWAPDLNCICYMGNQKSRDT-KFNVLLTTYEYILKDRALGSIKWQFMAVDEAHRLKNAESSLYESLNSFKVANRMLITGTPLQNNIKELAALVNFLMPGRFTIDQEIDFENQ---DEEQEEYIHDLHRRIQPFILRRLKKD--VEKSLP 607
12 -24.6005lfp_A mol:protein length:131 Bacterial proteasome activator  ali model follow..  19  72...EDAVPSDAELRIAQAQLVGWLEGLFHGIQTALFAQQMAARAQLQQMR.................................................................................................................................................................................... 118
13 -24.3005lzp_1 mol:protein length:180 Bacterial proteasome activator  ali model follow..  14  106...EDAVPSDAELRIAQAQLVGWLEGLFHGIQTALFAQQMAARAQLQQMRQGALPPGVGKSGQH...................................................................................................................................................................... 166
14 -21.0005tnu_A mol:protein length:459 DNA-dependent ATPase XPBII  ali model follow..  17  80.........KIELRDYQAEAVKAWLKEKR----GIIVLPTGAGKTQVALKIVSIMKVA-----TLIVVPTDLITQWKERINKYLD-FDPGIIGGGEDSLK----GITVITYDSAYTRAEELGNKFPLLIFDEVHHL--PSEGYSIMAQLFASPYRLGLTATPERDDGKHELYPIEELAGKYIAKYKIKK--LYVSLTNEEKKRYDGLRKKLKDFLSSRGLKLQN...... 288
15 -21.0002fwr_A mol:protein length:472 DNA repair protein RAD25  ali model follow..  17  83.......DAEISLRDYQEKALERWLVDKR----GCIVLPTGSGKTHVAMAAINELSTP-----TLIVVPTALAEQWKERLGIFGEE-YVGEFSGRIKELK----PLTVSTYDSAYVNAEKLGNRFMLLIFDEVHHL--PAESYVQIAQMSIAPFRLGLTATFEREDGRHE-LFPDSLAGKHLAKYTIKR--IFVPLAEDERVEYEKREKVYKQFLRAR............ 287
16 -18.4005hkx_A mol:protein length:392 E3 ubiquitin-protein ligase CBL  ali model follow..  14  22.......................................................................................KVVRLCQNPKLALKNSLDLLPDTYQHLRTILSLGENEYFRVFMENLMKKTKQTISLFKEGKERRNLTKLSLIFSHMLAELKGIFPSGLFQGDTFRDAAEFWRKAFGEKTWKSFRQALHEVHPISSGLEAMALKSTIDLTCN.. 190
17 -18.0005sva_Z mol:protein length:843 DNA repair helicase RAD25  ali model follow..  20  353...DIDLKPSTQIRPYQEKSLSKMFGNGRARSG-IIVLPCGAGKTLVGITAACTIKK-----SVIVLCTSSSVMQWRQQFLQWCQPENCAVFTSDNKEMFQTESGLVVSTYSMVANTDFLTGREWGFIILDEVHVV--PAAMFRRVVSTIAAHAKLGLTATLVDDKIGDLNFLIELSQKGHIANVQCAEVWCPMTAEFYQEYLRETARKRMLLYIMNPTKFQ........ 589
18 -17.9005ivw_V mol:protein length:782 TFIIH basal transcription factor complex helicase XPB subunit  ali model follow..  19  307...NIDLKPTAVLRPYQEKSLRKMFGNGRARSG-VIVLPCGAGKSLVGVTAACTVRK-----RCLVLGNSASVEQWKAQFKMWSDDSQICRFTSDAKDKP-IGCSVAISTYSMLGHTTKLKTQEWGLMILDEVHTI--PAKMFRRVLTIVQAHCKLGLTATLVDDKIVDLNFLIELQNNGYIAKVQCAEVWCPMSPEFYREYVAIKTKKRILLYTMNPNK.......... 540
19 -15.7002oca_A mol:protein length:510 ATP-dependent DNA helicase uvsW  ali model follow..  10  109.......NKRIEPHWYQKDAVFEGLVNRR----RILNLPTSAGRSLIQALLARYYLENYEGKILIIVPTTALTTQMADDFVDYRLMIKKIGGGASKDDKYKNDAPVVVGTWQTVVKQPKEWFSQFGMMMNDECHLA--TGKSISSIISGLNCMFKFGLSGSLRDGKANIM-TTSKLMEDGQVTELKINSIFLRYPDEFTTKLKGKTYQEEIK-IITGLSKRNKWIAKLA. 340
20 -14.5005jaj_A mol:protein length:681 LGP2  ali model follow..  12  9...........ELHGYQLE----AVAPALRGRNSIVWLPTGAGKTRAAVHVCRRHLEGRRGGRVAVLVNKVHLVQQHLEKHVLRDAFKVTAVSGDSFGQLAKGSDVVICTAQILQNALLVELTDFSLLVIDECHHTEAVYNKIMLSYLQKKLSGQLGLTASPGTGGETSFEGAVEHILQ-----CANLDTEVIASAQEHAQHLQSHVPQPTKQYDLCQEREQDPFGQRL. 240
21 -13.9003h1t_A mol:protein length:590 Type I site-specific restriction-modification system, R (Restriction) subunit  ali model follow..  14  178...........SPRYYQQIAINRAVQSVLQG--SLITMATGTGKTVVAFQISWKLWSARWNRTGFLADRNVLVDDPKDKTFTPFGDARHKIEGGKVVK----SREIYFAIYQSIASDEEFPQDFFDLIIIDECRGSARDNSNWREILEYFEPAFQIGMTATPLREDNRDTYRYFG-IDDGFLAPYRVHR......................................... 378
22 -13.4003b6e_A mol:protein length:216 Interferon-induced helicase C domain-containing protein 1  ali model follow..  20  33...........QLRPYQME----VAQPALEGKNIIICLPTGSGKTRVAVYIAKDKKKASEPGKVIVLVNKVLLVEQLFRKWYRVIGLSGDTQLKISFPEVVKSCDIIISTAQILENSLLVQLSDFSLIIIDECHHTNKEAVYNNIMRHYLMQKLKLGLTAS..................................................................... 216
23 -13.2004zni_A mol:protein length:274 Phage terminase large subunit  ali model follow..  10  19........LGYKPHHVQLA------IHRSTAKRRVACLGRQSGKSEAASVEAVFELFARPGSQGWIIAPTIIFGRVVEKVERLAEVFPATEVQLQRRRLRLLAPGAKRVATSEFRRPDNLRGATLDFVILDEAAMIPFSVWSEAIEPTLSVRDGWALIISTP-LNWFYEFFL.......................................................... 196
24 -12.9002kbe_A mol:protein length:226 ATP-dependent RNA helicase DBP5  ali model follow..  18  34............LKGIYAMKFQKPSKIQERALPLLLHNQSGTGKTAASLTMLTRVNPEDASPQAICLAPSRELARQTLEMGKFTKITSQLIVPDSFEKNKQINAQVIVGTPGTVLRRKLMQLQKIKIFVLDEADNMLDQQDQCIRVKRFLPKDTQLVLFSATFADAVRQY............................................................ 211
25 -12.7003tbk_A mol:protein length:555 RIG-I Helicase Domain  ali model follow..  14  4...........KPRNYQLE----LALPAKKGKNTIICAPTGCGKTFVSLLICLKKFPCGQKGKVVFFANQIPVYEQQATVGYNIASISGATSDSVSVQHIIEDNDIIILTPQILVNNLNPSLSVFTLMIFDECHNTNHPYNQIMFRYLDHKLGESVGLTASVAEEAMQHICKLCAALDASVIATVRDNVAELEQVVYKPQKISRKVASRTSNTF................ 233
26 -12.4004gl2_A mol:protein length:699 Interferon-induced helicase C domain-containing protein 1  ali model follow..  17  7...........QLRPYQME----VAQPALEGKNIIICLPTGCGKTRVAVYIAKDKKKASEPGKVIVLVNKVLLVEQLFRKWYRVIGLSGDTQLKISFPEVVKSCDIIISTAQILENSLLVQLSDFSLIIIDECHHTEAVYNNIMRHYLMQKLKNNLGLTASPGVGGATKQAKAEEHI----LKLCANLDAFTIKTVKENLDQLKNQIQEPCKKFAIADATREDPFKEKL. 254
27 -12.4001wp9_A mol:protein length:494 ATP-dependent RNA helicase, putative  ali model follow..  17  9...........QPRIYQEVIYA-----KCKETNCLIVLPTGLGKTL-IAMMIAEYRLTKYGGKVLMLAPTKPLVLQHAESFRRLFNLPPEKIVAEERSKAWARAKVIVATPQTIENDLLISLEDVSLIVFDEAHRANYAYVFIAREYKRQAKNPLVGLTASPGST................................................................. 169
28 -12.4004on9_A mol:protein length:580 Probable ATP-dependent RNA helicase DDX58  ali model follow..  13  23...........KPRNYQLE----LALPAMKGKNTIICAPTGCGKTFVSLLICLKKFPQGQKGKVVFFANQIPVYEQQKSVFSKYFERHGYRVTGVPVEQIVENNDIIILTPQILVNNLKKGTIIFTLMIFDECHNTSKQHPYNMIMFNYLDQKLGIGLTASVGVGDAKNTDEALDYIC.................................................... 209
29 -12.3005ffj_A mol:protein length:1406 Endonuclease and methylase LlaGI  ali model follow..  16  13...........KLRDYQQTAKENALAHFKENDRGQLIMAPGTGKTFTSLKISEALSKDKNGP-VLYLVPSQTLRGWNNDTELTITSMAVQNWHDFESLPKQTDMLVVFSTYEVIGEAQKEGFPEFDFIISDEAHRTTGAHEAAKEA-NNVKGLKRMYQTATPAKKNAKDKSILLSSMDDESKYGEVFFRMGFGQAVSRDILTDYKVMVLAVDEAAIQKDMQRTLADPE.. 285
30 -12.3005jc3_A mol:protein length:701 Melanoma differentiation associated protein-5  ali model follow..  18  7...........TLRDYQME----VAKPALNGENIIICLPTGSGKTRVAVYITKDKRKASEQGKVIVLVNKVPLVEQHLRKEFNPFLKHWYQVIGISFPEVVKRYDVIICTAQILENSLLVRLSDFSLIIIDQCHHTEGVYNNIMRRYLKEKIKNRLGLTASPGSKAEEHILKICANLDACRIMTVKEHASQLKNQVKEPFKKTVIADDKRRDPF................ 249
31 -12.3004bpb_A mol:protein length:698 PROBABLE ATP-DEPENDENT RNA HELICASE DDX58  ali model follow..  14  13...........KPRNYQLE----LALPAMKGKNTIICAPTGCGKTLLICEHHLKKFPQGQKGKVVFFANQIPVYEQNKSVFSKYFERHGYRVTGVPVEQIVENNDIIILTPQILVNNLKPSLSIFTLMIFDECHNTQHPYNMIMFNYLDQKLGGSIGLTASVTDEALDYICKLCASLDASVIATVKHNLEELEQVVYKPQKFFRKVESRISDKF................ 242
32 -12.2004a2w_A mol:protein length:936 RETINOIC ACID INDUCIBLE PROTEIN I  ali model follow..  17  248...........KARSYQIE----LAQPAINGKNALICAPTGSGKTFVSILICFQNMPAGRKAKVVFLATKVPVYEQQKNVFKHHFERQGYSVQGVSVEKVIEDSDIIVVTPQILVNSFETSLSIFTLMIFDECHNTNHPYNVLMTRYLEQKFNSALGLTASVIEETIEHICSLCSYLDIQAISTVRENIQELQRFMNKPEIDVRLVKRRIHNPF................ 476
33 -12.0002oxc_A mol:protein length:230 Probable ATP-dependent RNA helicase DDX20  ali model follow..  13  44..FERPSPVQLKAIPLGRCGLDLIVQAKS-----------GTGKTCVSTIALDSLVLENLSTQILILAPTR-IHSVITAIGIKMEGLECHVFIGSQDKTRLKKCHIAVGSPGRIKELDYLNPGSIRLFILDEADKLLEEGSQINWIYSSLPASKQMLAVSATYPEFLANALTKY........................................................ 219
34 -11.9006gpg_A mol:protein length:714 Probable ATP-dependent RNA helicase DDX58  ali model follow..  14  25...........KPRNYQLE----LALPAMKGKNTIICAPTGFGKTLLICEHHLKKFPQGQKGKVVFFANQIPVYEQQKSVFSKYFERHGYRVTGVPVEQIVENNDIIILTPQILVNNLKPSLSIFTLMIFDECHNTQHPYNMIMFNYLDQKLGGSIGLTASVTDEALDYICKLCASLDASVIATVKHNLEELEQVVYKPQKFFRKVESRISDKF................ 254
35 -11.3004xqk_A mol:protein length:1578 LlaBIII  ali model follow..  16  175.........PKKLRDYQQTAKENALAHFKENDRGQLIMAPGTGKTFTSLKISEALSKDKDPFKVLYLVPSQTLRGWNNDTEL-SSKKILQNWHDFESLPKQTDMLVVFSTYEVIGEAQKEGFPEFDFIISDEAHRTTGAHEAAKEA-NNVKGLKRMYQTATPAKKNAKDKSILLSSMDDESKYGEVFFRMGFGQAVSRDILTDYKVMVLAVDEAAIQKDMQRTLADPE.. 449
36 -11.1004zcf_C mol:protein length:970 Restriction endonuclease EcoP15I, restriction subunit  ali model follow..  15  81..................................DVSMETGTGKTYTYIKTIFDLNKSFGINKFIIIVPTGTVNFLKSDALKYKRELRTYVVESQKNAGNKKYIHVLVINSGMINSKSLTDTYDTGFIIIDEPHRFPT-GKKTWENIEKFNAQYIIRYGATFSEGYKNLVYR---------LTAVDAFNDDLVKGID................................. 282
37 -10.8003kql_A mol:protein length:437 Serine protease/NTPase/helicase NS3  ali model follow..  16  13..................................HLHAPTGSGKSTKVPAAYAAQGYK-----VLVLNPSVAAT--LGFGAYMSKAHGIDPNIRTGVRTITTGAPITYSTYGKFLADGGCSGGAYDIIICDECHSTDSTTILGIGTVLDQAETAGVLATATP.................................................................... 137
38 -10.8006bu9_A mol:protein length:1724 Dicer-2, isoform A  ali model follow..  16  11.............RGYQLRLVD-----HLTKSNGIVYLPTGSGKTFVAILVLFDKPIESGGKRALFMCNTVELARQQAMAVRRCTNFKVGFYVGEQGSDEIKKNQVLVGTAQVFLDMVTVALSSLSVVIIDECHHGHHPFREFMRLFTIANQTKLVGLTGVLVATKLKELEITYR....................................................... 198
39 -10.6003rvb_A mol:protein length:493 RNA helicase  ali model follow..  16  51..................................HLHAPTGSGKSTKVPAAYAAQGYK-----VLVLNPSVAAT--LGFGVYMSKAHGIDPNIRTGVRAITTGGPITYSTYGKFLADGGCSGGAYDIIICDECHSTDSTSILGIGTVLDQAETAGVLATATP.................................................................... 175
40 -10.5002f55_A mol:protein length:435 polyprotein  ali model follow..  16  12..................................HLHAPTGSGKSTKVPAAYAAQGYK-----VLVLNPSVAAT--LGFGAYMSKAHGIDPNIRTGVRTITTGGSITYSTYGKFLADGGCSGGAYDIIICDECHSTDSTTILGIGTVLDQAETAGVLATATP.................................................................... 136
41 -10.3004wxp_A mol:protein length:451 NS3-4 protease  ali model follow..  15  22..................................HLHAPTGSGKSTKVPAAYAAQGYK-----VLVLNPSVAAT--LGFGVYMSKAHGIDPNIRTGVRAITTGGPITYSTYGKFLADGGCSGGAYDIIICDECHSTDSTSILGIGTVLDQAETAGVLATATPPGSVTVSHPNI......................................................... 157
42 -10.2003ly5_A mol:protein length:262 ATP-dependent RNA helicase DDX18  ali model follow..  21  57.........ENTLKAIKEMGFTNMTEIQHKSIRPLLAAKTGSGKTLAFLIPAVELIVKLRFMPVLILSPTR-TFGVLKELMTHHVHTYGLIMGGSNRSAEAQKLNIIVATPGRLQNTPGFMYKNLQCLVIDEADRILD-EEELKQIIKLLPTRRQTMLFSATQTRKVEDLARISLKKEPLYVG............................................... 256
43 -10.2004ojq_A mol:protein length:464 Serine protease NS3  ali model follow..  16  29..................................HLHAPTGSGKSTKVPAAYAAQGYK-----VLVLNPSVAAT--LGFGAYMSKAHGVDPNIRTGVRTITTGSPITYSTYGKFLADGGCSGGAYDIIICDECHSTDATSILGIGTVLDQAETAGVLATATP.................................................................... 153
44 -10.2001gm5_A mol:protein length:780 RECG  ali model follow..  14  363......KSLPFKLTNAQKRAHQEIRMISEKPMNRLLQGDVGSGKTVVAQLAILDNYEAG---QTAFMVPTSILAHYRRTVESFSKNIHVALLIGATTPSEKEQIDVVIGTHALIQEDVHFKNL--GLVIIDEQHRF----KQREALMNKGKMVDTLVMSATPIPRSMA---AFYGDLDVTVIDEMPPGRKEVQTMLVPMDR------VNEVYEFVRQEVMRGGQAFIVYP 586
45 -10.1004b6e_A mol:protein length:683 NON-STRUCTURAL PROTEIN 4A, SERINE PROTEASE NS3  ali model follow..  15  230..................................HLHAPTGSGKSTKVPAAYAAQGYK-----VLVLNPSVAAT--LGFGAYMSKAHGIDPNIRTGVRTITTGAPVTYSTYGKFLADGGCSGGAYDIIICDECHSTDSTTILGIGTVLDQAETAGVLATATP.................................................................... 354
46 -10.0001a1v_A mol:protein length:476 PROTEIN (NS3 PROTEIN)  ali model follow..  16  36..................................HLHAPTGSGKSTKVPAAYAAQGYK-----VLVLNPSVAAT--LGFGAYMSKAHGVDPNIRTGVRTITTGSPITYSTYGKFLADGGCSGGAYDIIICDECHSTDATSILGIGTVLDQAETAGVLATATP.................................................................... 160
47 -9.9702zjo_A mol:protein length:482 Genome polyprotein  ali model follow..  16  46..................................HLHAPTGSGKSTKVPAAYAAQGYK-----VLVLNPSVAAT--LGFGAYMSKAHGVDPNIRTGVRTITTGAPITYSTYGKFLADGGCSGGAYDIIMCDECHSTDSTTILGIGTVLDQAETAGVLATATP.................................................................... 170
48 -9.9601t6n_A mol:protein length:220 Probable ATP-dependent RNA helicase  ali model follow..  17  26............LRAIVDCGFEHPSEVQHECIPQAILGKSGMGKTAVVLATLQQLEPVTGQVSVLVMCHTR-ISKEYERFSKYMPNVKVAVFFGGLEVLKKNCPHIVVGTPGRILRNKSLNLKHIKHFILDECDKMLEQRRDVQEIFRMTPHEKQVMMFSATLSKEIRPV............................................................ 207
49 -9.9103fmp_B mol:protein length:479 ATP-dependent RNA helicase DDX19B  ali model follow..  20  104............LQGVYAMGFNRPSKIQENALPLMLAEQSGTGKTAAVLAMLSQVEPANKYPQCLCLSPTY-TGKVIEQMGKFYPELKLAYAVRGNERGQKISEQIVIGTPGWCSKLKFIDPKKIKVFVLDEADVMIATQDQSIRIQRMLPRNCQMLLFSATFEDSVWKF............................................................ 284
50 -9.7803ber_A mol:protein length:249 Probable ATP-dependent RNA helicase DDX47  ali model follow..  18  55LGWTKPTKIQIEAIPLALQGRDIIGLAET-----------GSGKTGAALPILNALLETPQRLFALVLTPTELAFQISEQFEALGSSIGVVIVGGIDSMSQSLALHIIIATPGHLENTKGFNLRALKYLVMDEADRILNMDTEVDKILKVIPRDRKTFLFSATMTKKVQKL............................................................ 228
51 -9.7102pl3_A mol:protein length:236 Probable ATP-dependent RNA helicase DDX10  ali model follow..  19  34.........KKTLKGLQEAQYRLVTEIQKQTIGLALQGKTGSGKTLAFLVPVLEALYRLQWTSVLIISPTR-TFEVLRKVGKNHDFSAGLIIGGKDEAERINNINILVCTPGRLDETVSFHATDLQMLVLDEADRILDMGDTMNAVIENLPKKRQTLLFSATQTKSVKDL............................................................ 219
52 -9.6805wdx_A mol:protein length:649 JFH-1 NS3  ali model follow..  15  219..................................YLHAPTGSGKSTKVPVAYAAQGYK-----VLVLNPSVAAT--LGFGAYLSKAHGINPNIRTGVRTVMTGEAITYSTYGKFLADGGCASGAYDIIICDECHAVDATSILGIGTVLDQAETAGVLATATP.................................................................... 343
53 -9.6103b85_A mol:protein length:208 Phosphate starvation-inducible protein  ali model follow..  16  2.........NAVIRPKTLGQKHYVDAIDTNTI--FGLGPAGSGKTYLAMAKAVQALQSKQVSRIILTRPAVEAGE--TLNEKIDPYLRPLMVEPEVIPKLMEAGIVEVAPLAYMR-----RTLNDAFVILDEAQNTTPAQMKM--FLTRLGFGSKMVVTGDITQVDL............................................................... 163
54 -9.6103bor_A mol:protein length:237 Human initiation factor 4A-II  ali model follow..  17  36............LRGIYAYGFEKPSAIQQRAIIPCIKGQSGTGKTATAISILQQLEIEFKETQALVLAPTELAQQIQKVILALGDYMGATCVRNEMQKLQAEAPHIVVGTPGRVFNRRYLSPKWIKMFVLDEADEMLSRGDQIYEIFQKLNTSIQVVLLSATMPTDVLEVTKKF........................................................ 219
55 -9.4405wx1_A mol:protein length:733 Serine protease NS3  ali model follow..  19  266..................................QITLATGAGKTTELPRSVI--EEIGRHKRVLVLIPLRAAASVYQYMRQKHPSIAFNLRIGEMKEGDMATG-ITYASYGYFCQMPQPKLVEYSFIFLDEYHCATPEQLAIMGKIHRFSENLRVAMTATP.................................................................... 396
56 -9.3101yks_A mol:protein length:440 Genome polyprotein [contains: Flavivirin protease NS3 catalytic subunit]  ali model follow..  20  1...................GSHML----KKGMTTVLDFHPGAGKTRRFLPQIL-AECARRRLRTLVLAPTRVV---LSEMKEAFHGLDVKFHTQAFSAHGSGREVIDAMCHATLTYRMLEPTVNWEVIIMDEAHFLDPASIAARGWAAHRARANEILMTATP.................................................................... 140
57 -9.2903vgo_A mol:protein length:394 E3 ubiquitin-protein ligase CBL-B  ali model follow..  14  9....................................ADRRTVEKTWKLMDKV-----------------VRLCQNPKLQLKNSPPYI----------------LDILPDTYQHLRLILSLSENEYFKIYIDSLMKKSKRAIRLFKESQDRRNLTKLSLIFSHMLAEIKAIFPNGQFQGDNFRITKADAAEFWRKFFGDK-RQCLHEVHQISSGLEAMALKSTIDLTCN.. 193
58 -9.2802eyq_A mol:protein length:1151 Transcription-repair coupling factor  ali model follow..  15  625...............................MDRLVCGDVGFGKT---VAMRAAFLAVDNHKQVAVLVPTTLLANFRDRFANWPVRIEMISRFRSAKEQT-GKIDILIGTHKLLQSDVKFKDL--GLLIVDEEHRF---GVRHKERIKAMRAN--LTLTATPIPRTLN--MAMSGMRDLSIIATPPARRLAVKTFVREYDSM-------VVREAILREILRGGQV..... 815
59 -9.2702bhr_A mol:protein length:451 RNA HELICASE  ali model follow..  14  23..................................IMDLHPGAGKTKRYLPAIV-REAIKRGLRTLILAPTRVV---AAEMEEALRGLPIRYQTPAIRAEHTGREIVDLMCHATFTMRLPIRVPNYNLIIMDEAHFTDPASIAARGYISTRVEMGEIFMTATP.................................................................... 151
60 -9.2002v6i_A mol:protein length:431 RNA HELICASE  ali model follow..  12  6..................................VLDLHPGAGKTRRVLPQLV-REAVKKRLRTVILAPTRVVA---SEMYEALRGEPIRYMTPAVQSERTGNEIVDFMCHSTFTMKLGVRVPNYNLYIMDEAHFLDPASVAARGYIETRVSMGDIFMTATP.................................................................... 134
61 -9.1603ews_A mol:protein length:445 ATP-dependent RNA helicase DDX19B  ali model follow..  20  68............LQGVYAMGFNRPSKIQENALPLMLAEQSGTGKTAAVLAMLSQVEPANKYPQCLCLSPTY-TGKVIEQMGKFYPELKLAYAVRGNERGQKISEQIVIGTPGWCSKLKFIDPKKIKVFVLDEADVMIATQDQSIRIQRMLPRNCQMLLFSATFEDSVWKF............................................................ 248
62 -9.1405z3g_Y mol:protein length:505 ATP-dependent RNA helicase HAS1  ali model follow..  20  51.........QPTLKAIEKMGFTTMTSVQARTIPPLLAGKTGSGKTLAFLIPAIELLHSLKFKPIIVITPTR-IFGVARELMEFHSQTFGIVIGGANRRQEAEKLNMLIATPGRLQNTKGFVFKNLKALIIDEADRILE-EDEMRQIIKILPNEDRSMLFSATQTTKVEDLARISLRPGPLFINVVPETDNSTADGLEQGYVVCDSDKRFLLLFSFLKRNQKKKIIV.... 294
63 -9.1004kbf_A mol:protein length:365 Heat resistant RNA dependent ATPase  ali model follow..  16  13............LEALHGRGLTTPTPIQAAALPLALEGRTGTGKTLPIAERLAPSQERGRKPRALVLTPTELALQVASELTAVAPHLKVVAVYGKQKEALLRGADAVVATPGRALRQGVLDLSRVEVAVLDEADEMLSMGEEVEALLSATPPSRQTLLFSATLPSWAKRLAERYMKNPVLINVIKDEPVTYEEEAVPAPVRGRLEVLSDLLRAMVFTRTKAETEEIAQ.. 256
64 -9.0902z83_A mol:protein length:459 Helicase/Nucleoside Triphosphatase  ali model follow..  15  25..................................VLDLHPGSGKTRKILPQII-KDAIQQRLRTAVLAPTRVVA---AEMAEALRGLPVRYQTSAVQREHQGNEIVDVMCHATLTHRLMSPNRNYNLFVMDEAHFTDPASIAARGYIATKVELGEIFMTATP.................................................................... 153
65 -9.0902wzq_A mol:protein length:619 NS3 PROTEASE-HELICASE  ali model follow..  15  191..................................IMDLHPGAGKTKRILPSIV-REALKRRLRTLILAPTRVVA---AEMEEALRGLPIRYQTPAVKSDHTGREIVDLMCHATFTTRLLSSTRNYNLIVMDEAHFTDPCSVAARGYISTRVEMGEIFMTATP.................................................................... 319
66 -9.0905gju_A mol:protein length:205 ATP-dependent RNA helicase DeaD  ali model follow..  15  13............LEALNDLGYEKPSPIQAECIPHLLNGQTGSGKTAASLPLLQNLDPELKAPQILVLAPTR-VAEAMTDFSKHMRGVNVVALYGGQRYDV-QGPQIVVGTPGRLLKRGTLDLSKLSGLVLDEADEMLRMGEDVETIMAQIPEGHQTALFSATMPEAIRRI............................................................ 192
67 -9.0805mz4_A mol:protein length:752 Genome polyprotein,Genome polyprotein  ali model follow..  19  274..................................QITLATGAGKTTELPRSVI--EEIGRHKRVLVLIPLRAAASVYQYMRQKHPSIAFNLRIGEMKEGD-MATGITYASYGYFCQMSQPK-VEYSFIFLDEYHCATPEQLAIMGKIHRFSENLRVAMTATP.................................................................... 404
FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Luz JG, Hassig CA, Pickle C, Godzik A., Meyer BJ, Wilson IA. XOL-1, primary determinant of sexual fate in C. elegans, is a GHMP kinase family member and a structural prototype for a class of developmental regulators. Genes Dev. 2003 Apr 15;17(8):977-90. Epub 2003 Apr 02.