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Query: d1e8ca3 c.72.2.1 (A:104-337) UDP-N-acetylmuramyl tripeptide synthetase MurE {Escherichia coli [TaxId: 562]}, from SCOP207

Results of FFAS03 search in PfamA32U
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst PSDNLRLVGVTGTNGKTTTTQLLAQWSQLLGEISAVMGTVGNGLLGKVIPTENTTGSAVDVQHELAGLVDQGATFCAMEVSSHGLVQHRVAALKFAASVFTNLSRDHLDYHGDMEHYEAAKWLLYSEHHCGQAIINADDEVGRRWLAKLPDAVAVSMEDHINPNCHGRWLKATEVNYHDSGATIRFSSSWGDGEIESHLMGAFNVSNLLLALATLLALGYPLADLLKTAARLQPLast
1 -88.900PF08245.12; MURE_THEMA/108-304; Mur ligase middle domain  ali follow..  31  1.........VTGTNGKTTTTMMIYHMLTSLGERGSVLTTAVKRILGNSYYDDITTPDAITILSAMKENREGGGKFFALEVSSHALVQQRVEGVRFDVGIFTNISRDHLDFHGTFENYLKAKLHLFDLLKDGVAVLNESLADAFN----RKSRKITFGTS------KNADYRLGNIEVSWEGTQFVLETPDGLLKVFTRAIGDFNAYNAAAAIAAL................... 197
2 -31.000PF16292.5; A9WF69_CHLAA/4-305; Domain of unknown function (DUF4938 topsan)  ali follow..  16  175...RILIIAVTGERYRQQAIAEQAARHQGIILDQANRASVIT-------------------------LADPACTALIVGFDTDSLIREGLPFDRCDLAIITDRAGSRPPTAADDDEWLRALG-LPMLCSVAPTLINLTDPALHPLLSYAPNGVIGW.............................................................................. 302
3 -9.460PF07755.11; Q3J5L7_RHOS4/129-327; Domain of unknown function (DUF1611_C) P-loop domain  ali follow..  18  1PIANGRRMLAVGTDGKMYTALCVDREMRERGLKSSFRATTGILITGDGVPLDAVIADFMAGSIEYLTPDNEADHWDLIEGQG-GVTLALIHGGQPDALVICEPTRSHMRGLPSIEQVRDAALAMARVAVAVGCSINLSDEEALAYCAEIEART................................................................................. 179
4 -8.860PF07724.14; Q7PAG5_RICSI/595-759; AAA domain (Cdc48 subfamily)  ali follow..  18  2PLGSFLFLGPTGV-GKTELTKALAGFL--FDDRNAILGYIGYDQGGVLTEAVRRRPYQVILFDEVEKAHPDIFNIMLQILDEGRLTDSQGITVDFKNTIISNLGAEILVNQKEDEDTYKVKDEVMEYVKAVFKFLNRLDEI............................................................................................. 165
5 -8.430PF01591.18; F262_BOVIN/27-250; 6-phosphofructo-2-kinase  ali follow..  14  16....IVMIGLPAR-GKTYVSKKLTRYLNWIGVPTKVFNLGVYRRSGQIAVFDATNTTRERRDLILNFAEENSFKVFFVESDDPDVIAANILEVKVSSPDYPERNRENVDFLKRIECYKVTYQPL-DSHDKDLSFIKVINVGQRFLVNKVQDYIQS............................................................................... 211
6 -8.180PF01583.20; PAPS1_HUMAN/51-209; Adenylylsulphate kinase  ali follow..  16  5....VWLTGLSGA-GKTTVSMALEEYLVCHGIPCYTLDNIRQGLNKNLGFSPEDREENVRIAEVAKLFADAGLVCITSFISPYTQDRNNARQI---FEVFVDAPLHVCEQRDVKGLYKKARA................................................................................................................ 129
7 -8.090PF03029.17; O01426_CAEEL/6-251; Conserved hypothetical ATP binding protein  ali follow..  12  1......VIGAPGA-GKSTFCAGLTDIFSQTKRPFLTI-NLDPANDTMAYAPDVNITEMITVNDVMDRLGPNGALKYCIETLGANCNW---------LQKIEANHKKYLDCPGQLELYKSEGERFLEKSGVRLCALHLADS.............................................................................................. 133
8 -7.970PF13238.6; A0B5Y2_METTP/3-117; AAA domain  ali follow..  16  1....IALTGTPGT-GKTT----VSGLLPFRVVNLNDLIRDGMSAGFDPERECLEADMDALEEKIEEIERSCGADEAIVLRLHPNVLRRRLEARGYSASIRENVEAEAID............................................................................................................................. 115
9 -7.710PF13671.6; B2JHT3_PARP8/20-178; AAA domain  ali follow..  13  2....VFICGHAGT-GKTTLAKRLIGPLMKATGEACCLDTLYGVYSAAAIGALTGDPNDRD-SPLFLQHFRDPEYRGLFDTAAENLRLGI--GVIAVGPLSREVRERRLFDHVWLGVPKDAKISVV............................................................................................................. 121
10 -7.670PF13500.6; B1XHZ8_SYNP2/6-216; AAA domain  ali follow..  9  1..QHIVVASTEPYSGKSAVLLGLVQSLKQKGISVAYSKPIGTVWHDEQNGRFTRIEDDLRFLGEAFGLKETEVRSPVLTVAQRLTGQDQTDYPQKLKDDLGAIASDITFIEAP-----------------SLWEGSLFNLSAGEIAATLGAKILLVIPYHHKLLVDSLLTIYRFLGDRLMGVVINKIPPEALETAEIDVYGLVPADRILRSVT..................... 211
FFAS is supported by the NIH grant R01-GM087218-01
1 4 8 0 6 0   jobs submitted since Jan 1, 2011
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Damiano JS, Stehlik C, Pio F, Godzik A., Reed JC. CLAN, a novel human CED-4-like gene. Genomics. 2001 Jul;75(1-3):77-83.