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Query: d1edza1 c.2.1.7 (A:149-319) Methylenetetrahydrofolate dehydrogenase/cyclohydrolase {Baker`s yeast (Saccharomyces cerevisiae) [TaxId: 4932]}, from SCOP207

Results of FFAS03 search in SCOP207
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst PCTPLAIVKILEFLKIYNNLLPEGNRLYGKKCIVINRSEIVGRPLAALLANDGATVYSVDVNNIQKFTRGESLKLNKHHVEDLGEYSEDLLKKCSLDSDVVITGVPSENYKFPTEYIKEGAVCINFACTKNFSDDVKEKASLYVPMTGKVTIAMLLRNMLRLVRNVELSKELast
1 -91.700d1edza1 c.2.1.7 (A:149-319) Methylenetetrahydrofolate dehydrogenase/cyclohydrolase {Baker`s yeast (Saccharomyces cerevisiae) [TaxId: 4932]}  ali model 3D-neighbors  100  1PCTPLAIVKILEFLKIYNNLLPEGNRLYGKKCIVINRSEIVGRPLAALLANDGATVYSVDVNNIQKFTRGESLKLNKHHVEDLGEYSEDLLKKCSLDSDVVITGVPSENYKFPTEYIKEGAVCINFACTKNFSDDVKEKASLYVPMTGKVTIAMLLRNMLRLVRNVELSKE 171
2 -60.800d4cjxa2 c.2.1.0 (A:125-297) automated matches {Trypanosoma brucei [TaxId: 999953]}  ali model 3D-neighbors follow..  26  20PCTASAVMELLRCSGV---------EICGKRVVVLGRGDIAGLPVATLLANEDATVTVVHSAT-----------------------PLCDIADIVRASDIVVSAAGQPGL-VRGEWIKLGAAVIDVGTGDVCFDVARKRAAYITPVPGGVTVSMLLKNTLTMFKRSVRA.. 173
3 -59.300d4b4ua2 c.2.1.0 (A:122-282) automated matches {Acinetobacter baumannii [TaxId: 575584]}  ali model 3D-neighbors follow..  26  18SATPAGIMTILKENNI---------EIAGKHAVVVGRSAILGKPMAMMLLQANATVTICHSR-------------------------TQNLPELVKQADIIVGAVGKAEL-IQKDWIKQGAVVVDAGFGDIQLQGIEEIASAYTPVPGGVTITTLIRQTVEAAEKA..... 159
4 -57.700d3ngxa2 c.2.1.0 (A:116-276) automated matches {Thermoplasma acidophilum [TaxId: 2303]}  ali model 3D-neighbors follow..  22  18PATPRAVIDIMDYYGY-----------HENTVTIVNRSPVVGRPLSMMLLNRNYTVSVCHSK-------------------------TKDIGSMTRSSKIVVVAVGRPGF-LNREMVTPGSVVIDVGIGDANFEDLSEYVEAITPVPGGVTATNILENVVKAAEFQKNN.. 160
5 -16.800d1li4a1 c.2.1.4 (A:190-352) S-adenosylhomocystein hydrolase {Human (Homo sapiens) [TaxId: 9606]}  ali model 3D-neighbors follow..  15  6..CRESLIDGIKRA--------TDVMIAGKVAVVAGYGD-VGKGCAQALRGFGARVIITEIDPINALQAAME-------------YEVTTMDEACQEGNIFVTTTGCIDIILGRHFMKDDAIVCNIGHFDVEID..................................... 118
6 -14.200d1saya1 c.2.1.4 (A:136-303) L-alanine dehydrogenase {Phormidium lapideum [TaxId: 32060]}  ali model 3D-neighbors follow..  17  30..........................VKPGKVVILGGG-VVGTEAAKMAVGLGAQVQIFDINV----ERLSYLETLFGSRVELLYSNSAEIETAVAEADLLIGAVRRAPILVPASLVRTGSVIVDVAVDQGGCVETLHPTSHTQPT......................... 151
7 -13.800d3fr7a1 c.2.1.0 (A:86-307) automated matches {Oryza sativa [TaxId: 39947]}  ali model 3D-neighbors follow..  13  17.....GHEEYIVRGGRNLFPLLPEAFKGIKQIGVIGWG-SQGPAQAQNLRDSLAEAKSDIVVKIGLRKGSKSFDEARAAGFTEESGTLGDIWETVSGSDLVLLLISDAAQA--FSHMKPNSILGLSH............................................ 141
8 -13.000d1mv8a3 c.26.3.1 (A:301-436) GDP-mannose 6-dehydrogenase, GDP-binding domain {Pseudomonas aeruginosa [TaxId: 287]}  ali model 3D-neighbors follow..  17  10.........................SHDTRKVGLLGLSDLRESPLAEMLIGKGYELRIFDRNVEYARVHGANKEYIESKIPHVSSLLVSDLDEVVASSDVLVLGNGDELFVDLVNKTPSGKKLVD.............................................. 118
9 -12.900d3fi9a1 c.2.1.0 (A:2-147) automated matches {Porphyromonas gingivalis [TaxId: 431947]}  ali model 3D-neighbors follow..  12  3..........................LTEEKLTIVGAAGMIGSNMAQTAAMMRLTPNLCLYDPFAVGLEGVAEEIRHCGFEGLNLTFTSDIKEALTDAKYIVSSGGAPR-MTREDLLKGNAEIAAQLGKDIKSYCPDCKHVIIIFNPADITGLVTLI.............. 135
10 -12.800d1l7da1 c.2.1.4 (A:144-326) Nicotinamide nucleotide transhydrogenase dI component {Rhodospirillum rubrum [TaxId: 1085]}  ali model 3D-neighbors follow..  21  27..........................VPPARVLVFG-VGVAGLQAIATAKRLGAVVMATDVRAATK-TAETAGGYAKEMGEEFRKKQAEAVLKELVKTDIAITTAKPAPVLITEEMVKPGSVIIDLAVEA......................................... 154
11 -12.300d4ypoa1 c.2.1.0 (A:1-180) automated matches {Mycobacterium tuberculosis [TaxId: 1773]}  ali model 3D-neighbors follow..  14  1...............MFYDDDADLSIIQGRKVGVIGYG-SQGHAHSLSLRDSGVQVRVGLKQG-----------SRSRPKVEEQGLDVDTPAEVAKWADVVMVLAPDTAQA--EPNLKPGDALFFGH............................................ 105
12 -12.200d1e5qa1 c.2.1.3 (A:2-124,A:392-450) Saccharopine reductase {Fungus (Magnaporthe grisea) [TaxId: 148305]}  ali model 3D-neighbors follow..  15  1...........................ATKSVLMLG-SGFVTRPTLDVLTDSGIKVTVACRTLESA--KKLSAGVQHSTPISLDVNDDAALDAEVAKHDLVISLIPY-HATVIKSAIRQKKHVVTTSYVSPAMMELDQAA............................... 111
13 -12.100d4r3na1 c.2.1.3 (A:2-127,A:330-358) Aspartate beta-semialdehyde dehydrogenase {Pneumococcus (Streptococcus pneumoniae) [TaxId: 1313]}  ali model 3D-neighbors follow..  8  1............................GYTVAVVGATGAVGAQMIKMLEESTLPIDKIRYLASARSAGKSLKFKDQDITIEETT------ETAFEGVDIALFSAGSSSAKYAPYAVKAGVVVVDLVVPEVNAHALDAHNGIIA--PNXAAWNSVQ............... 134
14 -12.100d1gpja2 c.2.1.7 (A:144-302) Glutamyl tRNA-reductase middle domain {Methanopyrus kandleri [TaxId: 2320]}  ali model 3D-neighbors follow..  15  21.........................SLHDKTVLVVGAGEMGKTVAKSLVDRGVRAVLVAN--------RTYERAVELARDLGGEAVRFDELVDHLARSDVVVSATAAPHPVIHVDDVRE-ILIIDIANPRDVEEGVENIEDVEV........................... 140
15 -11.600d1qp8a1 c.2.1.4 (A:83-263) Putative formate dehydrogenase {Pyrobaculum aerophilum [TaxId: 13773]}  ali model 3D-neighbors follow..  16  37.......................IPLIQGEKVAVLGLGE-IGTRVGKILAALGAQVRGFS-----------------RTPKEGPWRFTNSLEEALREARAAVCALPHTRGLVKYQLMAEDAVFVNVGRAEVLDRDGVLRI............................... 141
16 -11.600d3tnla2 c.2.1.0 (A:113-291) automated matches {Listeria monocytogenes [TaxId: 169963]}  ali model 3D-neighbors follow..  9  1...........DGTGYMRALKEAGHDIIGKKMTICGAG--AATAICIQAALDGVKEISIFNRKDDFYANEKINSKTDCKAQLFDIEDHEQLRKEIAESVIFTNATGGETLLPSADMLRPELIVSDVVYKPTKTRLLEIAEEQGCQTLNGL--GMMLWQGAKAFE....... 162
17 -11.400d2pv7a2 c.2.1.6 (A:92-243) Prephenate dehydrogenase TyrA {Haemophilus influenzae [TaxId: 727]}  ali model 3D-neighbors follow..  17  10.............................HKIVIVGGYGKLGGLFARYLRASGYPISILDRED------------------------WAVAESILANADVVIVSVPINLTL--KPYLTENMLLADLTSVKREPLAKMLEVH---PMFG....................... 113
18 -11.300d2hjsa1 c.2.1.3 (A:3-129,A:320-336) Usg-1 protein homolog PA3116 {Pseudomonas aeruginosa [TaxId: 287]}  ali model 3D-neighbors follow..  10  4..............................NVAVVGATGSVGEALVGLLDERDFPLHRLHLLASAESAGQRMGFAESSLRVGDVD------SFDFSSVGLAFFAAAAESRAHAERARAAGCSVIDLSMVSVNAERLASAAPFLLSSPXAALNAVLL............... 136
19 -11.200d1hwxa4 c.2.1.7 (A:209-501) Glutamate dehydrogenase {Cow (Bos taurus) [TaxId: 9913]}  ali model 3D-neighbors follow..  18  6.ATGRGVFHGIENF--YMSILGMTPGFGDKTFAVQGFGN-VGLHSMRYLHRFGAKCVAVGESDGSIWNPDGDFKLQHGTILGFPKAKIYEGSILEVDCDILIPAASEKQLRVKAKIIAEGA---NGPTTPQADKIFLERNIMVIP-AGGVTVSYFLKNL............ 181
20 -11.200d1sc6a1 c.2.1.4 (A:108-295) Phosphoglycerate dehydrogenase {Escherichia coli [TaxId: 562]}  ali model 3D-neighbors follow..  21  39.......................SFEARGKKLGIIGYGH-IGTQLGILAESLGMYVYFYDIENKLPLGNA---------------TQVQHLSDLLNMSDVVVPENPSTKNMMGAKLMKPGSLLINASRGTVVDIPALADALASKHLAGA...................... 154
21 -11.200d2hk8a2 c.2.1.7 (A:106-266) Shikimate 5-dehydrogenase AroE {Aquifex aeolicus [TaxId: 63363]}  ali model 3D-neighbors follow..  11  1...........DWIGFLKSLKSLIPEVKEKSILVLGAG--ASRAVIYALVKEGAKVFLWN----------RTKEKAIKLAQKFPLEVVNSPEEVIDKVQVIVNTTDEDPEIFNYDLIKKDHVVVDIIYKETKLLKKAKEKGAKL-LDG---LPMLLWQGIEAFK....... 143
22 -11.200d3dona2 c.2.1.7 (A:100-269) Shikimate 5-dehydrogenase AroE {Staphylococcus epidermidis [TaxId: 176279]}  ali model 3D-neighbors follow..  6  1...........DGIGYVNGLKQIYEGIEDAYILILGAGGASKGIANELYKIVRPTLTVAN----------RTMSRFNNWSLNINKINLSHAESHLDEFDIIINTTGNTDSVISLNRLASHTLVSDIVYNPYKTPILIEAEQRGNPIYNGL--DMFVHQGAESFK....... 146
23 -11.100d2egga2 c.2.1.7 (A:123-297) Shikimate 5-dehydrogenase AroE {Geobacillus kaustophilus [TaxId: 1462]}  ali model 3D-neighbors follow..  12  6...............VQALEEEMNITLDGKRILVIGAGGGARGIYFSLLSTAAERIDMANRT-----VEKAERLVREGDERRSAYFSLAEAETRLAEYDIIINTTSVEVQPLSLERLRPGVIVSDIIYNPLETKWLKEAKARGARVQNGV--GMLVYQGALAFE....... 153
24 -11.100d3hhpa1 c.2.1.0 (A:1-145) automated matches {Escherichia coli K-12 [TaxId: 83333]}  ali model 3D-neighbors follow..  14  2..............................KVAVLGAAGGIGQALALLLKTQLPSGSELSLYDIAPVTPGVAVDLSHIPTVKIKGFSGEDATPALEGADVVLISAGVAR-MDRSDLFNVNAGIV---------KNLVQQVAKTCP-----ACIGIITNPVNT......... 123
25 -11.000d1luaa1 c.2.1.7 (A:98-288) Methylene-tetrahydromethanopterin dehydrogenase {Methylobacterium extorquens [TaxId: 408]}  ali model 3D-neighbors follow..  19  5..TAAAGVALVVK--------AAGGSVKGKKAVVLAGTGPVGMRSAALLAGEGAEVVLCGRKLDKAQAAADSVNKRKVNVTAAETADDASRAEAVKGAHFVFTAGAIGLELLPQAAWQNESIVADYNA........................................... 126
26 -10.900d2naca1 c.2.1.4 (A:148-335) Formate dehydrogenase {Pseudomonas sp., strain 101 [TaxId: 306]}  ali model 3D-neighbors follow..  17  39.......................AYDLEAMHVGTVAAGR-IGLAVLRRLAPFDVHLHYTDRHRLPESVEKE-----------LNLTWHATREDMYPVCDVVTLNCPETEHMINDELFKRGAYIVNTARGKLCDRDAVARALESGRLAG....................... 157
27 -10.900d4jcoa1 c.2.1.5 (A:22-162) automated matches {Haloarcula marismortui [TaxId: 2238]}  ali model 3D-neighbors follow..  16  2..............................KVSVVGAAGTVGAAAGYNIALRDIEVVFVDIPDKEDDTVGQAADTNHGIAYDSNTRVRQGGYEDTAGSDVVVITAGIPR-QTRIDLAGDNAPIM---------EDIQSSLDEHND-----YISLTTSNPVDLL........ 125
28 -10.900d1j4aa1 c.2.1.4 (A:104-300) D-lactate dehydrogenase {Lactobacillus helveticus [TaxId: 1587]}  ali model 3D-neighbors follow..  18  38.......................GREVRDQVVGVVGTGH-IGQVFMQIMEGFGAKVITYDIFRNPELEKKG--------------YYVDSLDDLYKQADVIVPDVPANVHMINDESIKQDVVIVNVSRGPLVDTDAVIRGLDSGKIFG....................... 153
29 -10.900d4hp8a_ c.2.1.0 (A:) automated matches {Agrobacterium tumefaciens [TaxId: 176299]}  ali model 3D-neighbors follow..  16  4.........................SLEGRKALVTGANTGLGQAIAVGLAAAGAEVVCAARRAPDETLDIIAKDGGNASALLIDFADPLAAKDSFTDADILVNNAGIIRRADSVEFSELD--VMDVNLKALFFTTQAFAKELLAKGRSGVNIASLL............... 139
30 -10.900d2ag5a1 c.2.1.2 (A:1-245) Dehydrogenase/reductase SDR family member 6, DHRS6 {Human (Homo sapiens) [TaxId: 9606]}  ali model 3D-neighbors follow..  13  3.........................RLDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEKYPGIQTRVLDVTKKKQIDQFANEVERLDVLFNVAGFVHHGTVLDCEEKD--SMNLNVRSMYLMIKAFLPKMLAQKSGNIINMSSVASSV........... 138
31 -10.800d1gdha1 c.2.1.4 (A:101-291) D-glycerate dehydrogenase {Hyphomicrobium methylovorum [TaxId: 84]}  ali model 3D-neighbors follow..  15  42.......................GEKLDNKTLGIYGFGS-IGQALAKRAQGFDMDIDYFDTHRASSSDEASYQATFH-----------DSLDSLLSVSQFFSLNAPETRYFFNKASLPQGAIVVNTARGDLVDNELVVAALEAGRLAYA...................... 161
32 -10.800d2r6ja_ c.2.1.0 (A:) automated matches {Ocimum basilicum [TaxId: 39350]}  ali model 3D-neighbors follow..  14  3............................KSKILIFGGTGYIGNHMVKGSLKLGHPTYVFTRPNSSKTTLLDEFQSLGAIIVKGELDEHEKLVELMKKVDVVISALAFPQILDQFKILEAIKVAGNI............................................. 100
33 -10.700d5unla_ c.2.1.0 (A:) automated matches {Burkholderia multivorans [TaxId: 87883]}  ali model 3D-neighbors follow..  13  8.........................PYDGLRVLVTGGASGIGLAIADAFAECGARVHVCDASQAAIAALADRPSRAAIGATLADVSDRAAVERVFADVDVLVNNAGIAGPTGGIDEIDPAQ-TVAINLNAQFEFARRAVPLLRESKHGGAIIAL................. 145
34 -10.700d3un1a1 c.2.1.0 (A:0-236) automated matches {Rhizobium meliloti (Sinorhizobium meliloti) [TaxId: 382]}  ali model 3D-neighbors follow..  10  2.........................RNQQKVVVITGASQGIGAGLVRAYRDRNYRVVATSRSIKPSADPDIHTVAGDISKPETADRIVREGIERFGRIDSLVNNAGVFLAKPFVEMTQED--NLGVNVAGFFHITQRAAAEMLKQGSGHIV.................... 128
35 -10.600d4h15a1 c.2.1.0 (A:1-259) automated matches {Sinorhizobium meliloti [TaxId: 266834]}  ali model 3D-neighbors follow..  15  6.........................NLRGKRALITAGTKGAGAATVSLFLELGAQVLTTARARPEGLPEELFVEADLTTKEGCAIVAEATRQRL--GVDVIVHMLG................................................................. 85
36 -10.600d4dlla1 c.2.1.0 (A:29-190) automated matches {Polaromonas sp. [TaxId: 296591]}  ali model 3D-neighbors follow..  15  2...........................YARKITFLGTG-SMGLPMARRLCEAGYALQVWNRTPARA-----------ASLAALGATIHEQARAAARDADIVVSMLENGAVVQDVAAMKPGSLFLDMAS--ITPREARDHAARLTPVSGGTVGA.................. 129
37 -10.500d2g17a1 c.2.1.3 (A:1-153,A:309-334) N-acetyl-gamma-glutamyl-phosphate reductase ArgC {Salmonella typhimurium [TaxId: 90371]}  ali model 3D-neighbors follow..  14  3..............................NTLIVGASGYAGAELVSYVNRHTITALTVSAQSNDAGKLISDLHPQLKGIVDLPLQPMSDVRDFSADVDVVFLATAHESHDLAPQFLQAGCVVFDLGLAEWNVDKLNT--ANLIAVPGXLLKGAAA............... 161
38 -10.500d1bg6a2 c.2.1.6 (A:4-187) N-(1-D-carboxylethyl)-L-norvaline dehydrogenase {Arthrobacter, strain 1c [TaxId: 1663]}  ali model 3D-neighbors follow..  21  2.............................KTYAVLGLGN-GGHAFAAYLALKGQSVLAWDIDAQRQDRGAIIAEGPGLAGTAHPDLLTSDIGLAVKDADVILIVVPAIHHA--ASYISEGQLII............................................... 103
39 -10.300d1jaya_ c.2.1.6 (A:) Coenzyme F420H2:NADP+ oxidoreductase (FNO) {Archaeoglobus fulgidus [TaxId: 2234]}  ali model 3D-neighbors follow..  10  2..............................RVALLGGTGNLGKGLALRLATLGHEIVVGSRRE----EKAEAKAAEYRRIAGDASITGMKNEDAAEACDIAVLTIPWEHAIDTARDLKREKIVVSPGAKGFTYSSERSAAEIVAEVLESEKVVSALHTI............ 135
40 -10.300d3t4xa1 c.2.1.0 (A:1-264) automated matches {Anthrax bacillus (Bacillus anthracis) [TaxId: 1392]}  ali model 3D-neighbors follow..  16  4.........................QLKGKTALVTGSTAGIGKAIATSLVAEGANVLINGRREENVNETIKEIRAQYPDAILQPVVADLGTEQGCQDVDILINNLG................................................................. 91
41 -10.300d1ooea_ c.2.1.2 (A:) Dihydropteridin reductase (pteridine reductase) {Nematode (Caenorhabditis elegans) [TaxId: 6239]}  ali model 3D-neighbors follow..  14  1...........................SSGKVIVYGGKGALGSAILEFFKKNGYTVLNIDLSANDQADSNILVDGNKNWTEQEQSILETASSLQGSQVDGVFCVAG----KLATTHLKPGGLLQLTGAAAAMGPTTSSLAAKDSGLPDNSAVLTIMPVTLDTPMNRKWMPN 188
42 -10.200d3pk0a1 c.2.1.0 (A:1-258) automated matches {Mycobacterium smegmatis [TaxId: 246196]}  ali model 3D-neighbors follow..  12  3.........................DLQGRSVVVTGGTKGIGRGIATVFARAGANVAVAGRSTADIDACVADLDQLGSGKVIGVQTDVSDRAQCDALAGRAVEEFGGIDVVCANAGVFPDAPLATMTPEQ......................................... 107
43 -10.200d5je8a1 c.2.1.0 (A:1-163) automated matches {Bacillus cereus [TaxId: 226900]}  ali model 3D-neighbors follow..  25  2.............................KKIGFIGLG-NMGLPMSKNLVKSGYTVYGVDLNKEAE-----------ASFEKEGGIIGLSISKLAETCDVVFTSLPSPRAVEAVENGHSNVVFIDTSTVSPQLNKQLEEAAK-APVSGGVIGA.................. 128
44 -10.200d4h7pa1 c.2.1.0 (A:1-155) automated matches {Leishmania major [TaxId: 347515]}  ali model 3D-neighbors follow..  11  1..........................MSAVKVAVTGAAGQIGYALVPLIARGALELRLLDIEPALKALAGVEAELEDCAFPLLDKVVTADPRVAFDGVAIAIMCGAFPR-MERKDLLEMNARIFKEQGEAIAAVAASDCRVVVVGNPANTNALILLKSAQGKLNPRH.... 151
45 -10.200d2fwmx_ c.2.1.0 (X:) automated matches {Escherichia coli [TaxId: 562]}  ali model 3D-neighbors follow..  13  2.........................DFSGKNVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQEQYPFATEVMDVADAAQVAQVCQRLLAET-ERLDALVNAAGILRMGATDQLSKED--TFAVNVGGAFNLFQQTMNQFRRQRGGAIV.................... 127
46 -10.200d1mx3a1 c.2.1.4 (A:126-318) Transcription corepressor CtbP {Human (Homo sapiens), Ctbp1 [TaxId: 9606]}  ali model 3D-neighbors follow..  18  44.......................AARIRGETLGIIGLGR-VGQAVALRAKAFGFNVLFYDPY------------LSDGVERALGLQRVSTLQDLLFHSDCVTLHCGHNHHLINDFQMRQGAFLVNTARGGLVDEKALAQALKEGRIRGA...................... 162
47 -10.100d5vpsa1 c.2.1.0 (A:1-259) automated matches {Burkholderia ambifaria [TaxId: 398577]}  ali model 3D-neighbors follow..  14  4.........................GIAGKTALVCAASKGLGRGCAEALAAEGVNLVIVAEETAEEIRAASNVSVTAVACDITTPDGRAAALAACPQPDILVNNAGGP............................................................... 92
48 -10.100d3vpxa2 c.2.1.0 (A:145-363) automated matches {Sporosarcina psychrophila [TaxId: 1476]}  ali model 3D-neighbors follow..  16  4PVTAYGIYYGMKAA----KEAFGDDSLAGKTVAVQGVGN-VAYALCEYLHEEGAKLIITDINEEAVQRAVDAFGATAVGINEI----------YSQEADIFACALGAIINDETIPQLK--KVIAGSANNQLKETRIHEMGIVYAP-SGGVINV.................. 150
49 -10.000d4iuya_ c.2.1.0 (A:) automated matches {Acinetobacter baumannii [TaxId: 405416]}  ali model 3D-neighbors follow..  8  4.........................DVKDKYILITGASSGLGHHIAELFAKEGANIVICARRLERLKELESHIKNEYGVQVYTFALDVNDRSAVKDMLSSLEAEGVTIDVLINNAGVSDTKRFLDYNDED......................................... 108
50 -9.990d3d3wa_ c.2.1.2 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}  ali model 3D-neighbors follow..  13  4.........................FLAGRRVLVTGAGKGIGRGTVQALHATGARVVAVSRTQADLDSLVRECPGIEPVCVDLGDEATERALGSVGPVDLLVNNAAVALLQPFLEVTKEA--SFEVNLRAVIQVSQIVARGLIARGVPGAIVNV................. 134
51 -9.990d1h5qa_ c.2.1.2 (A:) Mannitol dehydrogenase {Mushroom (Agaricus bisporus) [TaxId: 5341]}  ali model 3D-neighbors follow..  8  6.........................SFVNKTIIVTGGNRGIGLAFTRAVAAAGANVAVIYRSAADAVEVTEKVGKEFGVKTKAYQCDVSNTDIVTKTIQQIDADLGPISGLIANAGVSVVKPATELTHED......................................... 110
52 -9.960d1nyta1 c.2.1.7 (A:102-271) Shikimate 5-dehydrogenase AroE {Escherichia coli [TaxId: 562]}  ali model 3D-neighbors follow..  16  1...........DGVGLLSDLERLSFIRPGLRILLIGAG--ASRGVLLPLLSLDCAVTITN----RTVSRAEELAKLFAHTGSIQALSMDELE--GHEFDLIISGISGDIPAIPSSLIHPGIYCYDMQKGKTPFLAWCEQRGSKRNADG---LGMLVAQAAHAFL....... 149
53 -9.820d3ai2a_ c.2.1.0 (A:) automated matches {Gluconobacter frateurii [TaxId: 38308]}  ali model 3D-neighbors follow..  14  4.........................GISGKVAVITGSSSGIGLAIAEGFAKEGAHIVLVARQVDRLHEAARSLKEKFGVRVLEVAVDVATPEGVDAVVESVRSSFGGADILVNNAGTGSNETIMEAADEK......................................... 108
54 -9.770d2ekpa_ c.2.1.0 (A:) automated matches {Thermus thermophilus HB8 [TaxId: 300852]}  ali model 3D-neighbors follow..  14  1............................ERKALVTGGSRGIGRAIAEALVARGYRVAIASRNPEEAAQSLGAVPLPTDLEKDDPKGLVKRALEALGGLHVLVHAAAVNVRKPALELSYEE--VLYLHLDVAFLLAQAAAPHMAEAGWGRVLFIGSVTTFT........... 133
55 -9.770d2gf2a1 c.2.1.0 (A:41-201) automated matches {Human (Homo sapiens) [TaxId: 9606]}  ali model 3D-neighbors follow..  18  1..............................PVGFIGLG-NMGNPMAKNLMKHGYPLIIYDVFPDAC-----------KEFQDAGEQVVSSPADVAEKADRIITMLPTSINAIEAKKVKKGSLLIDSSTIDPAVSKELAKEVE-APVSGGVGAA.................. 126
56 -9.760d1ja9a_ c.2.1.2 (A:) 1,3,6,8-tetrahydroxynaphthalene reductase {Fungus (Magnaporthe grisea) [TaxId: 148305]}  ali model 3D-neighbors follow..  10  3.........................PLAGKVALTTGAGRGIGRGIAIELGRRGASVVVNYGSSSKAAEEVVAELKKLGAQGVAIQADISKPSEVVALFDKAVSHFGGLDFVMSNSGMEVWCDELEVTQEL......................................... 107
57 -9.730d2cvza2 c.2.1.6 (A:2-157) Hydroxyisobutyrate dehydrogenase {Thermus thermophilus [TaxId: 274]}  ali model 3D-neighbors follow..  16  1.............................EKVAFIGLG-AMGYPMAGHLARRFPTLVWNRTFEKALRHQEEF-------------GSEAVPLERVAEARVIFTCLPTTREVYEVPYLREGTYWVDATSGEPEASRRLAERLR-APVSGGTSGA.................. 122
58 -9.710d5u2wa_ c.2.1.0 (A:) automated matches {Burkholderia cenocepacia [TaxId: 216591]}  ali model 3D-neighbors follow..  16  3.........................RLQGKRALVTGGSRGIGAAIAKRLAADGADVAITYEKSAERAQAVVAGIEALGRRAIAIQADSADPVAVRNAVDRVAEAFGGLDILVNNAGIFRAGSLDDLTLDD......................................... 107
59 -9.670d1txga2 c.2.1.6 (A:1-180) Glycerol-3- phosphate dehydrogenase {Archaeoglobus fulgidus [TaxId: 2234]}  ali model 3D-neighbors follow..  15  2..............................IVSILGAGA--GSALSVPLVDNGNEVRIFDTEILKSISAGREHPRLGVKLNGVEIFWPEQLEKCLENAEVVLLGVSTDGVL--LPYLKDQYIVLISKVPEAVWRLKHDLRERTVAITGPAIAREVAKRMPTTVVFSSPSES 160
60 -9.660d1ygya1 c.2.1.4 (A:99-282) Phosphoglycerate dehydrogenase {Mycobacterium tuberculosis [TaxId: 1773]}  ali model 3D-neighbors follow..  17  38......................SGTEIFGKTVGVVGLGR-IGQLVAQRIAAFGAYVVAYDPYVSPARAAQLGIELL-------------SLDDLLARADFILPKTPETAGLIDKEKTKPGVIIVNAARGGLVDEAALADAITGGHVRAA...................... 156
61 -9.620d1geea_ c.2.1.2 (A:) Glucose dehydrogenase {Bacillus megaterium [TaxId: 1404]}  ali model 3D-neighbors follow..  9  4.........................DLEGKVVVITGSSTGLGKSMAIRFATEKAKVVVNYRSKEDEANSVLEEIKKVGGEAIAVKGDVTVESDVINLVQSAIKEFGKLDVMINNAGLENPVSSHEMSLSD......................................... 108
62 -9.550d2uyya1 c.2.1.0 (A:262-429) automated matches {Human (Homo sapiens) [TaxId: 9606]}  ali model 3D-neighbors follow..  14  5...........................TDKKIGFLGLG-LMGSGIVSNLLKMGHTVTVWNRTAEKC-----------DLFIQEGARLGRTPAEVVSTCDITFACVSDPKAAKDLQGIRPGKCYVDMST--VDADTVTELAQVIAPVSGNQQLS.................. 133
63 -9.530d3ws7a1 c.2.1.0 (A:1-161) automated matches {Pyrobaculum calidifontis [TaxId: 410359]}  ali model 3D-neighbors follow..  16  2..............................RVGFIGLG-IMGGPMATHLLKAGFLAAVYNRTREKT-----------KPFAEAGVYVAESPADLAKRVDVVIVMVSDAPDVEQVEGARPGLIVVDMSTNSPDWARKFAERLA-APVTGGQKGA.................. 127
64 -9.500d2x5oa1 c.5.1.0 (A:1-93) automated matches {Escherichia coli [TaxId: 668369]}  ali model 3D-neighbors follow..  12  1........................ADYQGKNVVIIGLGL-TGLSCVDFFLARGVTPRVMDTRMTPPGLDKLP--------EAVERHTGSLNDEWLMAADLIVASPGIALAHPSLSAAADAGIEI............................................... 91
65 -9.470d3r1ia_ c.2.1.0 (A:) automated matches {Mycobacterium marinum [TaxId: 216594]}  ali model 3D-neighbors follow..  13  7.........................DLSGKRALITGASTGIGKKVALAYAEAGAQVAVAARHSDALQVVADEIAGVGGKALPIR-TQPDQVRGMLDQMDIAVCNAGIVSVQAMLDMPLEE--IQDTNVTGVFLTAQAAARAMVDQGLGGTIITT................. 145
66 -9.470d1hyea1 c.2.1.5 (A:1-145) MJ0490, lactate/malate dehydrogenase {Methanococcus jannaschii [TaxId: 2190]}  ali model 3D-neighbors follow..  17  2..............................KVTIIGASGRVGSATALLLAKEPKDLVLIGREHSINKLEGLREDIYDTRSDANIYVESDENLRIIDESDVVIITSGVPR-MSRMDLAKTNAKIVGKYAKKIAEICDTKIFVITNPV......................... 125
67 -9.450d2g5ca2 c.2.1.6 (A:30-200) Prephenate dehydrogenase TyrA {Aquifex aeolicus [TaxId: 63363]}  ali model 3D-neighbors follow..  12  2.............................QNVLIVGVG-FMGGSFAKSLRRSGFKGKIY-------YDINPESISKAVDLGIIDEGTTSIAKVEDFSPDFVMLSSPVRTFR--SYILSEDATVTDQGSVKGKLVYDLENI----PIAGT...................... 123
68 -9.430d5en4a_ c.2.1.2 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}  ali model 3D-neighbors follow..  14  1.......................GTRYAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPGAVFILCDVTQEDDSETIRRFGRLDCVVAGHHPPPQRPEETSAQGFRQLLELNLLGT-YTLTKLALPYLRKSQGNVINISSLVGAI........... 143
69 -9.430d4onea_ c.2.1.0 (A:) automated matches {Brucella melitensis [TaxId: 224914]}  ali model 3D-neighbors follow..  11  1.........................SRQRPVALVTGGRRGIGLGIARALAAKGFDLAITDRESDEAVIHELRGLGGKVAFFKSDLAAVKTHEATVFAVDCLVNNAG................................................................. 88
70 -9.420d4u8ga_ c.2.1.0 (A:) automated matches {Streptococcus agalactiae [TaxId: 211110]}  ali model 3D-neighbors follow..  14  10.........................SLEGKVALITGASYGIGFSIATAFARAGATIVFNDIKQELVDKGISAYKKLGIKAHGYVNEMVDKISQDVGVIDILVNNAGIIKRTPMLEMSAAD--VIDIDLNAPFIVSKAVLPGMIQKGHGKIINICAMMSEL........... 154
71 -9.410d3awda_ c.2.1.0 (A:) automated matches {Gluconobacter oxydans [TaxId: 442]}  ali model 3D-neighbors follow..  14  7.........................RLDNRVAIVTGGAQNIGLACVTALAEAGARVIIADLDEAMATKAVEDLRMEGHDVSSVV-TNTESVQNAVRSVDILVACAGICISEVKAEDMTDGQ-QVDINLNGMFRSCQAVGRIMLEQKQGVIVAIGSMSGLI........... 152
72 -9.410d1xu9a1 c.2.1.2 (A:24-289) 11-beta-hydroxysteroid dehydrogenase 1 {Human (Homo sapiens) [TaxId: 9606]}  ali model 3D-neighbors follow..  14  8.........................MLQGKKVIVTGASKGIGREMAYHLAKMGAHVVVTARSKETLQKVVSHCLELGAASAHYIAGTMEDMTFAEQFVAQAGKLMGGLDMLILNHITNTSLNLFHDDIHEVNFLSYVVLTVAALPM-GSIVVVSSLAGKV........... 152
73 -9.390d4e6pa_ c.2.1.2 (A:) automated matches {Sinorhizobium meliloti [TaxId: 266834]}  ali model 3D-neighbors follow..  15  2.........................RLEGKSALITGSARGIGRAFAEAYVREGATVAIADIDIERARQAAAEIGPAAYAVQ-MDVTRQDSIDAAIAATDILVNNAALFDLAPIVEITRES--LFAINVAGTLFTLQAAARQMIAQGRGGKIINM................. 137
74 -9.340d3sx2a_ c.2.1.0 (A:) automated matches {Mycobacterium avium [TaxId: 262316]}  ali model 3D-neighbors follow..  16  2.........................PLTGKVAFITGAARGQGRAHAVRLAADGADIIAVDLEELAATVKLVEDIGSRIVARQADVRDRESLSAALQAGDIVVANAGIAPMSAGDDGWHD---VIDVNLTGVYHTIKVAIPTLVKQGTGGSIVLI................. 148
75 -9.280d3oida1 c.2.1.0 (A:3-250) automated matches {Bacillus subtilis [TaxId: 1423]}  ali model 3D-neighbors follow..  10  1...........................QNKCALVTGSSRGVGKAAAIRLAENGYNIVINYARSKKAALETAEEIEKLGVKVLVVKANVGQPAKIKEMFQQIDETFGRLDVFVNNAASGVLRPVMELEETH......................................... 103
FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Li W, Godzik A. Discovering new genes with advanced homology detection. Trends Biotechnol. 2002 Aug;20(8):315-6.