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Query: d1gm5a3 c.37.1.19 (A:286-549) RecG helicase domain {Thermotoga maritima [TaxId: 2336]}, from SCOP207

Results of FFAS03 search in SCOP207
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst ETLPERILEKRKLLGVKDAYYGMHFPKTFYHLEKARERLAYEELFVLQLAFQKIRKEREKHGGIPKKIEGKLAEEFIKSLPFKLTNAQKRAHQEIRNDMISEKPMNRLLQGDVGSGKTVVAQLAILDNYEAGFQTAFMVPTSILAIQHYRRTVESFSKFNIHVALLIGATTPSEKEKIKSGLRNGQIDVVIGTHALIQEDVHFKNLGLVIIDEQHRFGVKQREALMNKGKMVDTLVMSATPIPRSMALAFYGDLDVTVIDEMPPLast
1 -117.000d1gm5a3 c.37.1.19 (A:286-549) RecG helicase domain {Thermotoga maritima [TaxId: 2336]}  ali model 3D-neighbors  100  1ETLPERILEKRKLLGVKDAYYGMHFPKTFYHLEKARERLAYEELFVLQLAFQKIRKEREKHGGIPKKIEGKLAEEFIKSLPFKLTNAQKRAHQEIRNDMISEKPMNRLLQGDVGSGKTVVAQLAILDNYEAGFQTAFMVPTSILAIQHYRRTVESFSKFNIHVALLIGATTPSEKEKIKSGLRNGQIDVVIGTHALIQEDVHFKNLGLVIIDEQHRFGVKQREALMNKGKMVDTLVMSATPIPRSMALAFYGDLDVTVIDEMPP 264
2 -68.000d2eyqa3 c.37.1.19 (A:546-778) Transcription-repair coupling factor, TRCF {Escherichia coli [TaxId: 562]}  ali model 3D-neighbors follow..  35  9....................................RQKAAEKVRDVAAELLDIYAQRAAKEGFAFKHDREQYQLFCDSFPFETTPDQAQAINAVLSDMCQPLAMDRLVCGDVGFGKTEVAMRAAFLAVDNHKQVAVLVPTTLLAQQHYDNFRDRFANWPVRIEMISRFRSAKEQTQILAEVAEGKIDILIGTHKLLQSDVKFKDLGLLIVDEEHRFGVRHKERIKAMRANVDILTLTATPIPRTLNMAMSGMRDLSIIAT... 233
3 -23.200d1yksa1 c.37.1.14 (A:187-324) YFV helicase domain {Yellow fever virus [TaxId: 11089]}  ali model 3D-neighbors follow..  19  8..........................................................................................................TVLDFHPGAGKTRRFLPQILACARRRLRTLVLAPTRVVLSEMKEAFH---------------GLDVKFHTQAFSAHGSGREVIDAMCHATLTYRMRVVNWEVIIMDEAHSIAARGWAAHRARANESATILMTATP-P..................... 138
4 -22.500d1wp9a1 c.37.1.19 (A:1-200) putative ATP-dependent RNA helicase PF2015 {Pyrococcus furiosus [TaxId: 2261]}  ali model 3D-neighbors follow..  21  18..................................................................................................YAKCKETNCLIVLPTGLGKTLIAMMIAEYRLTYGGKVLMLAPTKPLVLQHAESFRRLFNLPPEKIVALTGEKSPEERSKAWA-----RAKVIVATPQTIENDLSLEDVSLIVFDEAHR--VFIAREYKRQAKNPLVIGLTASPGSTPEKIEVINNLGIEHIE.... 186
5 -22.500d1rifa_ c.37.1.23 (A:) DNA helicase UvsW {Bacteriophage T4 [TaxId: 10665]}  ali model 3D-neighbors follow..  19  111................................................................................RIEPHWYQKDAVFEGLVN-------RRILNLPTSAGRSLIQALLARYYLENEGKILIIVPTTALTTQMADDFVDYRLFSHAMIKKIGGGASKDDKYKNDA-------PVVVGTWQTVVKQPKFSQFGMMMNDECHLAGKSISSIISGLNNCMFKFGLSGSL....................... 262
6 -21.400d2p6ra3 c.37.1.19 (A:1-202) Hel308 helicase {Archaeoglobus fulgidus [TaxId: 2234]}  ali model 3D-neighbors follow..  20  25..................................................................................ELFPPQAEAVEKVFSG-------NLLLAMPTAAGKTLLAEMAMVREAIKGGKSLYVVPLRALAGEKYESFKK-WEKIGLRIGISTGDYESRDEH--------GDCDIIVTTSEKADSLIRIKAVSCLVVDEIHLLDSEKRTKMRRMNKALRVIGLSAT-APNVTEIAEWLDADY........ 196
7 -19.900d1gkub1 c.37.1.16 (B:6-250) Helicase-like "domain" of reverse gyrase {Archaeoglobus fulgidus [TaxId: 2234]}  ali model 3D-neighbors follow..  20  26......................................................................KEFVEFFRKCVGEPRAIQKMWAKRILRKES-------AATAPTGVGKTSFGLAMSLFLALKGKRCYVIFPTSLLVIQAAETIRKYAEKAGVGTENLIGRIPKREKENFMQNLRN--FKIVITTTQFLSKHYRLGHFDFIFVDDVDAFHYDLKTKSWVGEARGCLMVSTAT-AKKGKKAELFRQL.......... 221
8 -19.400d2fz4a1 c.37.1.19 (A:24-229) DNA repair protein RAD25 {Archaeoglobus fulgidus [TaxId: 2234]}  ali model 3D-neighbors follow..  24  69.................................................................................ISLRDYQEKALERWLVD-------RGCIVLPTGSGKTHVAMAAI---NELSTPTLIVVPTLALAEQWKERLGIFGEE---YVGEFSGRIKELK-------------PLTVSTYDSAYVNAEKNRFMLLIFDEVHHLPAESYVQIAQMSIAPFRLGLTATF....................... 205
9 -16.900d1a1va1 c.37.1.14 (A:190-325) HCV helicase domain {Human hepatitis C virus (HCV), different isolates [TaxId: 11103]}  ali model 3D-neighbors follow..  16  12...........................................................................................................HLHAPTGSGKSTKVPAAYA---AQGYKVLVLNPSVAATLGFGAYMSK---AHGVDPNIRTGVRTI---------TTGSPITYSTYGKFLADGGCSGGAYDIIICDECHSLGIGTVLDQAETAGARLVVLATATP....................... 136
10 -16.500d2pl3a1 c.37.1.0 (A:47-278) automated matches {Human (Homo sapiens) [TaxId: 9606]}  ali model 3D-neighbors follow..  22  45..................................................................................LVTEIQKQTIGLALKDV--------LGAAKTGSGKTLAFLVPVLEALTDGLGVLIISPTRELAYQTFEVLRKVGKNHDFSAGLIIGGKDLKHEAERINN-----INILVCTHMDETVSFHATDLQMLVLDEADRFADTMNAVIENLPKKRQTLLFSATQTKSVKDLA............... 218
11 -16.300d1gm5a4 c.37.1.19 (A:550-755) RecG helicase domain {Thermotoga maritima [TaxId: 2336]}  ali model 3D-neighbors follow..  14  2........................................................................................RKEVQTMLVPMDRVNEVYEFVRQEVMRGGQAFIVYPLIEESDKLNVKSAVEMYEYLSKEVFP---------EFKLGLMHGRLSQEEKDRVMLEFAEGRYDILVST-TVIEVGIDVPRANVMVIENPERFGLAQLHQLRGR.................................... 131
12 -15.600d1qdea_ c.37.1.19 (A:) Initiation factor 4a {Baker`s yeast (Saccharomyces cerevisiae) [TaxId: 4932]}  ali model 3D-neighbors follow..  20  34....................................................................................SAIQQRAIMPIIEG------HDVLAQAQSGTGKTGTFSIAALQRIDTS-QALMLAPTRELALQIQKVVMALAFHMDIKVHACIGGTSFVEDAEGLRD-----AQIVVGTPGRVRRRFRTDKIKMFILDEADEFKEQIYQIFTLLPPTTQVVLLSATMPNDVLEVT............... 200
13 -15.400d3bera_ c.37.1.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}  ali model 3D-neighbors follow..  20  38....................................................................................TKIQIEAIPLALQG------RDIIGLAETGSGKTGAFALPILNALLQRLFALVLTPTRELAFQISEQFEALGSSIGVQSAVIVGGIDSMSQSLALAK----KPHIIIATHLENTKGFNLRALKYLVMDEADRFETEVDKILKVIPRDRKTFLFSATMTKKVQKLQ............... 206
14 -15.100d3dkpa1 c.37.1.0 (A:139-378) automated matches {Human (Homo sapiens) [TaxId: 9606]}  ali model 3D-neighbors follow..  16  51....................................................................................TPIQMQAIPVMLHG------RELLASAPTGSGKTLAFSIPILMQLKQGFRALIISPTRELASQIHRELIKISEGTGFRIHMIHKAAVAAKK---FGPKSSKKFDILVTTPNRLIYGIDLASVEWLVVDESDKFRDQLASIFLACTSHKVRRAMFSATFAYDV.................. 222
15 -14.800d3peya1 c.37.1.0 (A:91-286) automated matches {Baker`s yeast (Saccharomyces cerevisiae) [TaxId: 4932]}  ali model 3D-neighbors follow..  19  26....................................................................................SKIQERALPLLLHN----PPRNMIAQSQSGTGKTAAFSLTMLTRVNPEDQAICLAPSRELARQTLEVVQEMGKFTKITSQLIVPDSFEKNKQI--------NAQVIVGTPGTVRKLMQLQKIKIFVLDEADNLGDQCIRVKRFLPKDTQLVLFSATFADAVRQYA............... 192
16 -14.700d1t6na_ c.37.1.19 (A:) Spliceosome RNA helicase BAT1 (UAP56) {Human (Homo sapiens) [TaxId: 9606]}  ali model 3D-neighbors follow..  21  25....................................................................................SEVQHECIPQAILG------MDVLCQAKSGMGKTAVFVLATLQQLEGQVSVLVMCHTRELAFQISKEYERFSKYMNVKVAVFFGGLSIKKD---EEVLKKNCPHIVVGTPGRINKSLNLKHIKHFILDECDKMRRDVQEIFRMTPHEKQVMMFSATLSKEIRPVC............... 195
17 -14.700d2z0ma1 c.37.1.0 (A:1-192) automated matches {Sulfolobus tokodaii [TaxId: 111955]}  ali model 3D-neighbors follow..  20  18....................................................................................TEVQSKTIPLMLQG------KNVVVRAKTGSGKTAAYAIPIL---ELGMKSLVVTPTRELTRQVASHIRDIGRYMDTKVAEVYGGMPYKAQINRVRN-----ADIVVATPGRLKGVIDLSSFEIVIIDEADLFIDDIKIILAQTSNRKITGLFSATIPEEIRKVV............... 178
18 -14.500d2oxca_ c.37.1.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}  ali model 3D-neighbors follow..  20  25....................................................................................SPVQLKAIPLGRCG------LDLIVQAKSGTGKTCVFSTIALDSLVLSTQILILAPTREIAVQIHSVITAIGIKMGLECHVFIGGTPLSQDKTRLKK-----CHIAVGSQLIELDYLNPGSIRLFILDEADKFQEQINWIYSSLPASKQMLAVSAT-YPEFLA................. 190
19 -14.000d1q0ua_ c.37.1.19 (A:) Probable DEAD box RNA helicase YqfR {Bacillus stearothermophilus [TaxId: 1422]}  ali model 3D-neighbors follow..  22  25....................................................................................TEIQERIIPGALRG------ESMVGQSQTGTGKTHAYLLPIMEKIKPE-QAVITAPTRELATQIYHETLKITKFCMIVARCLIGGTDKQKALEKLNV----QPHIVIGTPGRINDALDVHTAHILVVDEADLFITDVDQIAARMPKDLQMLVFSATKLKPFLKKYMENPTFVHVL..... 209
20 -13.500d4ct4b1 c.37.1.0 (B:95-301) automated matches {Human (Homo sapiens) [TaxId: 9606]}  ali model 3D-neighbors follow..  17  26....................................................................................SPIQEESIPIALSG------RDILARAKNGTGKSGAYLIPLLERLDDNIQAMVIVPTRELALQVSQICIQVSKHMGAKVMATTGGTNLRDDIMRLDD----TVHVVIATPGRIKGVAKVDHVQMIVLDEADKFVQIMEDIILTLPKNRQILLYSATSVQKFMNSHLQKPYEINLM..... 207
21 -13.100d1z63a1 c.37.1.19 (A:432-661) Helicase of the SNF2/Rad54 hamily {Sulfolobus solfataricus [TaxId: 2287]}  ali model 3D-neighbors follow..  16  7.............................................................................YNIKANLRPYQIKGFSWMR--FMNKLGFGICLADDMGLGKTLQTIAVFSDAKKEN-PSLVICPLSVLKNWEEELSK------HLRFAVFHEDRSKIKLE---------DYDIILTTYAVLLRDTRLKEVKYIVIDEAQNI--TKIFKAVKELKSKYRIALTGTPIENKVD................. 168
22 -13.000d2i4ia3 c.37.1.0 (A:168-406) automated matches {Human (Homo sapiens) [TaxId: 9606]}  ali model 3D-neighbors follow..  20  37....................................................................................TPVQKHAIPIIKEK------RDLMACAQTGSGKTAAFLLPILSQIYSYPISLVLAPTRELAVQIYEEARKFSYRSRVRPCVVYGGADIGQQ---IRDLERG-CHLLVATPGRLVDKIGLDFCKYLVLDEADRFEPQIRRIVEQDTMPPHTMMFSAT-FPKEI.................. 222
23 -13.000d1oywa2 c.37.1.19 (A:1-206) RecQ helicase domain {Escherichia coli [TaxId: 562]}  ali model 3D-neighbors follow..  17  25..................................................................................QFRPGQEEIIDTVLSG------RDCLVVMPTGGGKSLCYQIPALLL------TVVVSPLISLMKDQVDQLQA----NGVAAACLNSTQTREQQLEVMTGCRTGQIRLLYIAPERLMLDLAHWNPVLLAVDEAHRPEYAALGQLRQRFPTLPFMALTATADDTT................... 188
24 -12.900d3iuya1 c.37.1.0 (A:213-439) automated matches {Human (Homo sapiens) [TaxId: 9606]}  ali model 3D-neighbors follow..  19  63..............................................................................................................AQTGTGKTLSYLMPGFIHLDSGPGMLVLTPTRELALHVEAECSK-YSYKGLKSICIYGGRNRNGQ---IEDISKG-VDIIIATPGRLNDSVNLRSITYLVIDEADKFEPQIRKILLDVRPDRQTVMTSAT-WPDTV.................. 211
25 -12.800d1z3ix2 c.37.1.19 (X:92-389) Rad54-like, Rad54L {Zebrafish (Danio rerio) [TaxId: 7955]}  ali model 3D-neighbors follow..  17  51..............................................................................VLSKVLRPHQREGVKDCVTGRRIENSYGCIMADEMGLGKTLQCITLIWTLLKQS-KVIVVSPSSLV-RNWYNEVGKWLGGRVQPVAIDGGSKDEIDSKLVNFISQQGPTPILIISYETFREVLHKGKVGLVICDEGHRLSDNQTYLALNSMNAQRRVLISGTPIQNDLL---------SLVHFVNS 247
26 -12.600d3mwja_ c.37.1.0 (A:) automated matches {Thermus thermophilus [TaxId: 262724]}  ali model 3D-neighbors follow..  19  25....................................................................................TPIEAAALPLALEG------KDLIGQARTGTGKTLAFALPIAERLAPS-RALVLTPTRELALQVASELTAVAP--HLKVVAVYGGTGYGKQKEALLR----GADAVVATPGRAQGVLDLSRVEVAVLDEADEFEEEVEALLSATPPSRQTLLFSATLPSWAKRLA............... 193
27 -12.600d1c4oa2 c.37.1.19 (A:410-583) Nucleotide excision repair enzyme UvrB {Thermus thermophilus [TaxId: 274]}  ali model 3D-neighbors follow..  15  1....................................................................................TGLLDPLVRVKPTENQILDLMEGIRERAARGERTLV----------------------VLTVRMAEELTSFLVEHGIRARYLHHELDAFKRQALIRDLRLGHYDCLVGIN-LLREGLDIPEVSLVAILDADKEGFLR........................................... 115
28 -12.400d5gvra_ c.37.1.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}  ali model 3D-neighbors follow..  23  57..............................................................................................................AFTGSGKTLVFTLPVIMFCLEGPYGLIICPSRELARQTHGILEYYCRLLQLRCALCIGGMSVKEQ---METIRHG-VHMMVATPGRLMDMVSLDICRYLALDEADRFEGDIRTIFSYFKGQRQTLLFSAT-MPKKI.................. 214
29 -12.100d5y4za1 c.37.1.14 (A:178-481) automated matches {Zika virus (strain mr 766) [TaxId: 64320]}  ali model 3D-neighbors follow..  19  14...........................................................................................................VLDLHPGAGKTRVLPEIVREAIKKRLRTVILAPTRVVAAEMEEAL---------------RGLPVRYMTTAVNVTHSGTEIVDLMCHATLLQPIRVPNYNLNIMDEAHFTDPSSIAARRVEMGEAAAIFMTATP....................... 142
30 -11.500d2eyqa5 c.37.1.19 (A:779-989) Transcription-repair coupling factor, TRCF {Escherichia coli [TaxId: 562]}  ali model 3D-neighbors follow..  17  2.......................................................................................................PARRLVKTFVREYDSMVVREAILREILRGGQVYYLYNDVENIQKAAERLAELVPE--ARIAIGHGQMRERELERVMNDFHHQRFNVLVCT-TIIETGIDIPTANTIIIERADHFGLAQLHQLRGRVGRSHHQAYAWLLTPHPKAMTTDAQKRLEAIASL.. 158
31 -10.300d1tf5a3 c.37.1.19 (A:1-226,A:349-395) Translocation ATPase SecA, nucleotide-binding domains {Bacillus subtilis [TaxId: 1423]}  ali model 3D-neighbors follow..  15  54....................................................................KGATTDDLLVEAFAVVREASRRVTGMFPFKVQLMGGVGNIAEMKTGEGKTLTSTLPVYLNALTGKGVHVVTVNEYLASRDAEQMGKIFEFLGLTVGLNLNSMSKDEKREAYAANNELGFDYLRDNMVLYKEQMVQRPLHFAVIDE---------SILIDEARTPLIISMTGTAKTEEEEFRNIYNMQVVTI..... 271
32 -10.100d2gk6a1 c.37.1.19 (A:295-324,A:416-702) Upf1 {Human (Homo sapiens) [TaxId: 9606]}  ali model 3D-neighbors follow..  15  86..................................................................................DLNHSQVYAVKTVLQR---------LIQGPPGTGKTVTSATIVYHLARQGNGPVLVAPSNIAVD----QLTEKIHQTGLKVVRLCAKSREAIDSPVSFLALHMNADVICCT-GAGDPRLAKMQFRSILIDE------------STQATEPECMVPVVLGAKQ---LILVGD------CQLGP 284
33 -9.790d2g2jc_ c.37.1.0 (C:) automated matches {Human (Homo sapiens) [TaxId: 9606]}  ali model 3D-neighbors follow..  17  13................................................................................................................CEHRKDKYQALCNIYGSITIGQAIIFCQTRRNAKW----LTVEMIQDGHQVSLLSGELTVEQRASIIQRFRDGKEKVLITTN-VCARGIDVKQVTIVVNFD-HRIGRTGRF---KKGLAFNMIEVDELPSLMKIQDHFNSSIKQLNAED... 168
34 -9.520d2j0sa2 c.37.1.19 (A:244-411) automated matches {Human (Homo sapiens) [TaxId: 9606]}  ali model 3D-neighbors follow..  20  14...............................................................................................................AVEREEWKFDTLCDLYDTLTITQAVIFCNTKRKVDW----LTEKMREANFTVSSMHGDMPQKERESIMKEFRSGASRVLISTD-VWARGLDVPQVSLIINYD-HRIGRSGRY......................................... 128
35 -9.430d3peya2 c.37.1.0 (A:287-481) automated matches {Baker`s yeast (Saccharomyces cerevisiae) [TaxId: 4932]}  ali model 3D-neighbors follow..  18  24...............................................................................................................DCKNEADKFDVLTELYGLMTIGSSIIFVATKKTANV----LYGKLKSEGHEVSILHGDLQTQERDRLIDDFREGRSKVLITTN-VLARGIDIPTVSMVVADPAHRIGRTGRF......................................... 144
36 -9.260d1w36d1 c.37.1.19 (D:2-360) Exodeoxyribonuclease V alpha chain (RecD) {Escherichia coli [TaxId: 562]}  ali model 3D-neighbors follow..  14  90......................VSRGDEPTPMILCGDRLYLNRMWCNERTVARFFNEVNHAIEVDEALLAQTLDKLFPVS--DEINWQKVAAAVALTR---------VISGGPGTGKTVAKLLAALIQMGERCRIRLAAPTGKAAARLTESLGKALRQLPLTDEQKKRIPEDASTLHRLLGAQPGSQRLRHHAGNPLHLDV-------LVVDEASMIDLPMMSRLIDA-------------LPDHARVIFLGDRD-AVLGDI.. 312
37 -9.010d2hjva_ c.37.1.0 (A:) automated matches {Bacillus subtilis [TaxId: 1423]}  ali model 3D-neighbors follow..  14  19........................................................................................................................SLLKDVLMTENPDSCIIFCRTKEHVNQ----LTDELDDLGYPCDKIHGGMIQEDRFDVMNEFKRGEYRYLVATD-VAARGIDIENISLVI-SYVHRTGRTGRA......................................... 124
FFAS is supported by the NIH grant R01-GM087218-01
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Comments and questions to: webmaster
Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Rychlewski L, Zhang B, Godzik A. Functional insights from structural predictions: analysis of the Escherichia coli genome. Protein Sci. 1999 Mar;8(3):614-24.