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Query: d2dapa1 c.2.1.3 (A:1-118,A:269-320) Diaminopimelic acid dehydrogenase (DAPDH) {Corynebacterium glutamicum [TaxId: 1718]}, from SCOP207

Results of FFAS03 search in SCOP207
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MTNIRVAIVGYGNLGRSVEKLIAKQPDMDLVGIFSRRATLDTKTPVFDVADVDKHADDVDVLFLCMGSATDIPEQAPKFAQFACTVDTYDNHRDIPRHRQVMNEAATAAGNVALVSTGXRNPDFTASSQIAFGRAAHRMKQQGQSGAFTVLEVAPYLLSPENLDDLIARDVLast
1 -79.800d2dapa1 c.2.1.3 (A:1-118,A:269-320) Diaminopimelic acid dehydrogenase (DAPDH) {Corynebacterium glutamicum [TaxId: 1718]}  ali model 3D-neighbors  100  1MTNIRVAIVGYGNLGRSVEKLIAKQPDMDLVGIFSRRATLDTKTPVFDVADVDKHADDVDVLFLCMGSATDIPEQAPKFAQFACTVDTYDNHRDIPRHRQVMNEAATAAGNVALVSTGXRNPDFTASSQIAFGRAAHRMKQQGQSGAFTVLEVAPYLLSPENLDDLIARDV 171
2 -43.500d1tlta1 c.2.1.3 (A:5-127,A:268-308) Virulence factor MviM {Escherichia coli [TaxId: 562]}  ali model 3D-neighbors follow..  11  1..KLRIGVVGLGGIAQAWLPVLAAASDWTLQGAWSKALPICESWRIPYADSLSSLAASCDAVFVHSSTASHFDVVSTLLNAGVHVCVDKPLAENLRDAERLVELAARKKLTLMVGFNRRFXFVARHFIECVQNQTVPQT................................ 144
3 -41.000d1lc0a1 c.2.1.3 (A:2-128,A:247-291) Biliverdin reductase {Norway rat (Rattus norvegicus) [TaxId: 10116]}  ali model 3D-neighbors follow..  10  5SGKFGVVVVGVGRAGSVRLRDLKDPRSAAFLNLIGFVSRRELGSDEVRQISLEDALREIDVAYICSESSSHEDYIRQFLQAGKHVLVEYPMTLSFAAAQELWELAAQKGRVLHEEHVELLXKNFLKDQDIFVQKLLDQV................................ 147
4 -40.700d1xeaa1 c.2.1.3 (A:4-122,A:267-312) Putative oxidoreductase VCA1048 {Vibrio cholerae [TaxId: 666]}  ali model 3D-neighbors follow..  12  1....KIAMIGLGDIAQAYLPVLAQWPDIELV-LCTRNPKVLGTLA-ATCTDYRDVLQGVDAVMIHAATDVHSTLAAFFLHLGIPTFVDKPLAASAQECENLYELAEKHHQPLYVGFNXGFDAMVQDWLQVAAAGKLPTH................................ 141
5 -38.700d1zh8a1 c.2.1.3 (A:4-131,A:276-328) Hypothetical protein TM0312 {Thermotoga maritima [TaxId: 2336]}  ali model 3D-neighbors follow..  13  1LRKIRLGIVGCGIAARLHLPALKNLSHFEITAVTSRTRSHAEEFA-AVFDSYEELLELVDAVDLTLPVELNLPFIEKALRKGVHVICEKPISTDVETGKKVVELSEKSEKTVYIAENFRYQKEFEDFYQVVAEGKPNDL................................ 152
6 -35.700d1h6da1 c.2.1.3 (A:51-212,A:375-433) Glucose-fructose oxidoreductase, N-terminal domain {Zymomonas mobilis [TaxId: 542]}  ali model 3D-neighbors follow..  13  32.RRFGYAIVGLGKYALQILPGFAGCQHSRIEALVSGNAEKAKIVKIYDYSNFDKIAKDIDAVYIILPNSLHAEFAIRAFKAGKHVMCEKPMATSVADCQRMIDAAKAANKKLMIGYRCHYXNQFSAQLDHLAEAVINN................................. 180
7 -34.000d2q4ea1 c.2.1.3 (A:6-133,A:305-360) Probable oxidoreductase At4g09670 {Thale cress (Arabidopsis thaliana) [TaxId: 3702]}  ali model 3D-neighbors follow..  12  1..QIRIGVMGCADIARKVSRAIHLAPNATISGVASRSLEKAKAFSTKIHGSYESLLEDIDALYVPLPTSLHVEWAIKAAEKGKHILLEKPVAMNVTEFDKIVDACEANGVQIMDGTMWVHXPQEACMVREF-ARLVGEIKNNGA........................... 151
8 -32.900d2nvwa1 c.2.1.3 (A:-11-154,A:374-457) Galactose/lactose metabolism regulatory protein GAL80 {Milk yeast (Kluyveromyces lactis) [TaxId: 28985]}  ali model 3D-neighbors follow..  10  28.RPIRVGFVGLTSVAKTHFLAIQQLSSFQIVALYNPTLKSSLQTHATGFDSLESFAQDIDMIVVSVKVPEHYEVVKNILEHSSYLYVEWALAASVQQAEELYSISQQRANLTIICLQGRXYNSVRIYESIADYHFLGKP................................ 191
9 -31.200d1nvmb1 c.2.1.3 (B:1-131,B:287-312) Acetaldehyde dehydrogenase (acylating) {Pseudomonas sp. [TaxId: 306]}  ali model 3D-neighbors follow..  17  1MQKLKVAIIGSGNIGTDLMKVLRNAKYLEMGAMVGIDAASAQRMGVTTTYAGVEGLADIDFVFDATSASAHVQNELRQAKPGIRLIDLTPAAIGPYCVPVVNLEEHLGKLNVNMVTXYAGNLDIMTSAAL......................................... 145
10 -30.100d1j5pa4 c.2.1.3 (A:1-108,A:220-241) Hypothetical protein TM1643 {Thermotoga maritima [TaxId: 2336]}  ali model 3D-neighbors follow..  11  1...MTVLIIGMGNIGKKLVELG----NFEKIYAYDRISKDIPGV---VRLDEFQVPSDVSTVVECASPEAVKEYSLQILKNPVNYIIISTSAFADEVRERFFSELKNSPARVFFPSGXSM-SILRTLRNLESKIIFG.................................. 131
11 -27.000d1cf2o1 c.2.1.3 (O:1-138,O:304-336) Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) {Methanothermus fervidus [TaxId: 2180]}  ali model 3D-neighbors follow..  18  1M--KAVAINGYGTVGKRVADAIAQQDDMKVIGVSKTRPDFEEKAGIEVAGTVDDMLDEADIVIDCTPEGIGAKNLKMYKEKGIKAIFEKHEDIGLSFNSLSNYEESYGKDYTRVVXIVPENVDAVRAILEMEEDKYKSI................................ 162
12 -26.900d3keoa2 c.2.1.0 (A:82-212) automated matches {Streptococcus agalactiae [TaxId: 216495]}  ali model 3D-neighbors follow..  17  2.STTNVMLVGCGNIGRALLHYRFDRNKMQISMAFDLDSNDLVGIPVYGISTINDHLIDIETAILTVPSTEAQEVADILVKAGIKILSFSPVHLTLPKDIIVQYVDLTSELQTLLYFMNQ.................................................... 129
13 -24.300d1oi7a1 c.2.1.8 (A:1-121) Succinyl-CoA synthetase, alpha-chain, N-terminal (CoA-binding) domain {Thermus thermophilus [TaxId: 274]}  ali model 3D-neighbors follow..  11  6.RETRVLVQGIGREGQFHTKQMLTYGTKIVAGVTPGKGMEVLGVPVYDTVKEAVAHHEVDASIIFVPAPAAADAALEAAHAGIPLIVLITEGIPTLDMVRAVEEIKALGSRL........................................................... 118
14 -16.600d1t4ba1 c.2.1.3 (A:1-133,A:355-367) Aspartate beta-semialdehyde dehydrogenase {Escherichia coli [TaxId: 562]}  ali model 3D-neighbors follow..  8  2...QNVGFIGWGMVGSVLMQRMVEERDFDAIRPVFFSTSQLGQAAPSFGGTTLEALKALDIIVTCQGGDYTNEIYPKLRESGWQGYWIDAASSLRMKDDAIIILDPVNQDVITDGL----NNGIRTFVGGXAAEPLRRMLR.............................. 144
15 -16.600d1drua1 c.2.1.3 (A:4-130,A:241-273) Dihydrodipicolinate reductase {Escherichia coli [TaxId: 562]}  ali model 3D-neighbors follow..  20  1.ANIRVAIAGAGRMGRQLIQAALALEGVQLGAALEREGSSLGKTGVTVQSSLDAVKDDFDVFIDFTRPEGTLNHLAFCRQHGKGMVI-----GTTGFDEAGKQAIRDAAADIAIVFAANFSXMTFANGAVRS....................................... 138
16 -16.400d1ebua1 c.2.1.3 (A:2-150,A:341-359) Homoserine dehydrogenase {Baker`s yeast (Saccharomyces cerevisiae) [TaxId: 4932]}  ali model 3D-neighbors follow..  12  3.KVVNVAVIGAGVVGSAFLDQLLAMKTYNLVLLAEAEASTTKTLPLDDLIAHLKTSPKPVILVDNTSSAYIAGFYTKFVENGISIATKKAFSSDLATWKALFSNKPTNGFVYHEATVGAGLXAAVTAAGVLGDV..................................... 162
17 -16.300d2g17a1 c.2.1.3 (A:1-153,A:309-334) N-acetyl-gamma-glutamyl-phosphate reductase ArgC {Salmonella typhimurium [TaxId: 90371]}  ali model 3D-neighbors follow..  21  2...LNTLIVGAGYAGAELVSYVNRHPHMTITALTVSAQSNDAGKLISDLSDVRDFSADVDVVFLATAHEVSHDLAPQFLQAGCVVFD.................................................................................... 101
18 -15.700d1vkna1 c.2.1.3 (A:1-144,A:308-339) N-acetyl-gamma-glutamyl-phosphate reductase ArgC {Thermotoga maritima [TaxId: 2336]}  ali model 3D-neighbors follow..  21  2...IRAGIIGAGYTGLELVRLLKNHPEAKITYLSSRTYAGKKLEEIFSEFDPEKVSKNCDVLFTALPAGASYDLVRELKGVKI........................................................................................ 91
19 -15.600d1e5qa1 c.2.1.3 (A:2-124,A:392-450) Saccharopine reductase {Fungus (Magnaporthe grisea) [TaxId: 148305]}  ali model 3D-neighbors follow..  12  1.ATKSVLMLGSGFVTRPTLDVLTD-SGIKVT-VACRTLESAKKLDVNDDAALDAEVAKHDLVISLIPYTFHATVIKSAIRQKKHVVTTSYVSPAMMELDQAAKDAG-----ITVMNEIGXYSAMAKLVGVPCAVAVKFVLD.............................. 145
20 -15.600d1p9la1 c.2.1.3 (A:1-105,A:215-245) Dihydrodipicolinate reductase {Mycobacterium tuberculosis [TaxId: 1773]}  ali model 3D-neighbors follow..  14  1...MRVGVLGAGKVGTTMVRAVAAADDLTLSAELDAGDPLS-----------LLTDGNTEVVIDFTHPDVVMGNLEFLIDNGIHAVV---TTGFTAERFQQVESWLVAKPNTSVLIAPNFXTSFVPGVLLAVRRI.................................... 120
21 -15.500d2dt5a2 c.2.1.12 (A:78-211) Transcriptional repressor Rex, C-terminal domain {Thermus aquaticus [TaxId: 271]}  ali model 3D-neighbors follow..  11  2.RKWGLCIVGMGRLGSALADYPGFGESFELRGFFDVDPEKVGRGVIEHVDLLPQRVGRIEIALLTVPREAAQKAADLLVAAGIKGILNFAPVVLEVPKEVAVENVD................................................................. 111
22 -15.400d4ypoa1 c.2.1.0 (A:1-180) automated matches {Mycobacterium tuberculosis [TaxId: 1773]}  ali model 3D-neighbors follow..  13  12IQGRKVGVIGYGSQGHAHSLSLRDS-GVQVR-VGLKQGSRSRPKQGLDVDTPAEVAKWADVVMVLAPDTAQAEIFAGDIEPNLK....................................................................................... 96
23 -15.200d1i36a2 c.2.1.6 (A:1-152) Conserved hypothetical protein MTH1747 {Methanobacterium thermoautotrophicum [TaxId: 145262]}  ali model 3D-neighbors follow..  12  1...LRVGFIGFGEVAQTLASRLRS-RGVEVVTSLEGRSPSTIERTVGVTETSEEDVYSCPVVISAVTPGVALGAARRAGRHVRGIYVD--INNISPETVRMASSLIEKGGFVDAAIMGSVRRKGADIRIIASGRDAEEFMKLNRYG......................... 142
24 -14.900d3fr7a1 c.2.1.0 (A:86-307) automated matches {Oryza sativa [TaxId: 39947]}  ali model 3D-neighbors follow..  9  38KGIKQIGVIGWGSQGPAQAQNLRKSDIVVKIGLRKGSKSFDEARAAGTLGDIWETVSGSDLVLLLISDAAQADNYEKIMKPNSILGLSHGFLLGHLQSAGLD..................................................................... 154
25 -14.800d2i76a2 c.2.1.6 (A:2-154) Hypothetical protein TM1727 {Thermotoga maritima [TaxId: 2336]}  ali model 3D-neighbors follow..  17  2.....LNFVGTGTLTRFFLECLKD--RYEIGYILSRSIDRARNLAEVKAATLEKHPELNGVVFVIVPDRYIKTVANHLNLGDAVLV-----HCSGFLSSEIFKKSGRAS.............................................................. 101
26 -14.600d2hjsa1 c.2.1.3 (A:3-129,A:320-336) Usg-1 protein homolog PA3116 {Pseudomonas aeruginosa [TaxId: 287]}  ali model 3D-neighbors follow..  13  1.QPLNVAVVGAGSVGEALVGLLDERPLHRLHLLASAESAGQRESSLRVGDVDSFDFSSVGLAFFAAAAEVSRAHAERARAAGCSVIDLSG-ALEPSVAPPVMVSVNAERLASQAAPFLLSSPXAALNAVLL........................................ 136
27 -13.600d1li4a1 c.2.1.4 (A:190-352) S-adenosylhomocystein hydrolase {Human (Homo sapiens) [TaxId: 9606]}  ali model 3D-neighbors follow..  10  22IAGKVAVVAGYGDVGKGCAQALRGFGARVIITEIDPINALQAAMEGYEVTTMDEACQEGNIFVTTTGCID---------------IILGRHFEQMKDDAIVCNIGHFDVEI............................................................ 117
28 -13.600d1bg6a2 c.2.1.6 (A:4-187) N-(1-D-carboxylethyl)-L-norvaline dehydrogenase {Arthrobacter, strain 1c [TaxId: 1663]}  ali model 3D-neighbors follow..  13  1..SKTYAVLGLGNGGHAFAAYLALK-----VLAWDIDAQRIKEIQDLLTSDIGLAVKDADVILIVVPAIHHASIAANIISEGQLIILNPGATGGALEFRKILRENGAPEVTIG.......................................................... 130
29 -13.100d2f1ka2 c.2.1.6 (A:1-165) Prephenate dehydrogenase TyrA {Synechocystis sp. PCC 6803 [TaxId: 1148]}  ali model 3D-neighbors follow..  16  1...MKIGVVGLGLIGASLAGDLRRR-GHYLIGVSRQQSTCEKAVEVDEAGQDLSLLQTAKIIFLCTP----IQLILPTLEKLIPHLSPTAIVTDVASVKTAIAEPASQ............................................................... 103
30 -12.900d4r3na1 c.2.1.3 (A:2-127,A:330-358) Aspartate beta-semialdehyde dehydrogenase {Pneumococcus (Streptococcus pneumoniae) [TaxId: 1313]}  ali model 3D-neighbors follow..  19  2...YTVAVVGAGAVGAQMIKMLEEST-DKIRYLASARSAGKSDQDITIEETTETAFEGVDIALFSAGSSTSAKYAPYAVKAGVVVVDNTSYFRQNPDVPLVVPEVNAHA.............................................................. 114
31 -12.700d2rcya1 c.2.1.0 (A:2-156) automated matches {Plasmodium falciparum [TaxId: 36329]}  ali model 3D-neighbors follow..  14  1MENIKLGFMGLGQMGSALAHGIANANIIKKENLF--YGPSKKNTTLNYMSSNEELARHCDIIVCAVK-----PDIAGSVLNNIKPYLSSKLLISICGGLNIGKLEEMVGSENKIVWVMPNTPCLV.............................................. 119
32 -12.600d1j4aa1 c.2.1.4 (A:104-300) D-lactate dehydrogenase {Lactobacillus helveticus [TaxId: 1587]}  ali model 3D-neighbors follow..  12  41VRDQVVGVVGTGHIGQVFMQIMEGF-GAKVIT-YDIFRNPELEKKGYYVDSLDDLYKQADVISLHVP-----------DVPANVHMINDESIAKMKQDVVIVNVSRGP---------------------LVDTDAVIRGLDSGKIFGYAM..................... 156
33 -12.600d2g6ta1 c.147.1.1 (A:1-305) Hypothetical protein CAC2185 {Clostridium acetobutylicum [TaxId: 1488]}  ali model 3D-neighbors follow..  7  1MY--KCLIWGVNDEYTLAYDKLLFKGNLSIEALISKDKYAKYIDGKEVIDKTEISNYEFDYIIIFNKE....................................................................................................... 69
34 -12.400d2naca1 c.2.1.4 (A:148-335) Formate dehydrogenase {Pseudomonas sp., strain 101 [TaxId: 306]}  ali model 3D-neighbors follow..  15  42LEAMHVGTVAAGRIGLAVLRRLAPF-DVHLHYTHRLPESVEKELNLTWHATREDMYPVCDVVTLNCP-----------LHPETEHMINDETLKLFKRGAYIVNTARGK---------------------LCDRDAVARALESGRLAGYAG..................... 160
35 -12.300d1qp8a1 c.2.1.4 (A:83-263) Putative formate dehydrogenase {Pyrobaculum aerophilum [TaxId: 13773]}  ali model 3D-neighbors follow..  12  40IQGEKVAVLGLGEIGTRVGKILAAL-GAQVRGF----SRTPKEGPWRFTNSLEEALREARAAVCALP-----------LNKHTRGLVKYQHLALMAEDAVFVNVGRAE---------------------VLDRDGVLRILKERPQFIFAS..................... 152
36 -11.900d1mx3a1 c.2.1.4 (A:126-318) Transcription corepressor CtbP {Human (Homo sapiens), Ctbp1 [TaxId: 9606]}  ali model 3D-neighbors follow..  11  47IRGETLGIIGLGRVGQAVALRAKAFGFNVLFYDPYLSDGVERALGLQRVSTLQDLLFHSDCVTLHCG-----------LNEHNHHLINDFTVKQMRQGAFLVNTARGG---------------------LVDEKALAQALKEGRIRGAAL..................... 164
37 -11.800d2ahra2 c.2.1.6 (A:1-152) Pyrroline-5-carboxylate reductase ProC {Streptococcus pyogenes [TaxId: 1314]}  ali model 3D-neighbors follow..  12  1...MKIGIIGVGKMASAIIKGLKQTPHELIIS--ERSKEIAEQLALPYAMSHQDLIDQVDLVILGIKP--------QLFETVLKPLHFKQPIISMAAGISLQRLATFVGQDLPLLRI...................................................... 108
38 -11.400d2g5ca2 c.2.1.6 (A:30-200) Prephenate dehydrogenase TyrA {Aquifex aeolicus [TaxId: 63363]}  ali model 3D-neighbors follow..  11  3....NVLIVGVGFMGGSFAKSLRRSGKGKIYGYDINPESISKAVDLGIIDEGKVEDFSPDFVMLSSP----VRTFREIAKKLSYILSEDATVTDQGSVKGKLVYDLEN............................................................... 108
39 -11.300d3cmco1 c.2.1.3 (O:0-148,O:313-333) Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) {Bacillus stearothermophilus, nca 1503 [TaxId: 1422]}  ali model 3D-neighbors follow..  14  1..AVKVGINGFGRIGRNVFRAALKNPDIEVVAVNDLTDANTLAHLLKYDSVHGRLDAEVDIVVESTGRFTKREDAAKHLEAG---------------AKKVIISAPAKNEDITIVMGVNQDKYDPKAHHVISNAS.................................... 150
40 -11.200d1txga2 c.2.1.6 (A:1-180) Glycerol-3- phosphate dehydrogenase {Archaeoglobus fulgidus [TaxId: 2234]}  ali model 3D-neighbors follow..  16  1...MIVSILGAGAMGSALSVPLVDNGDTEILKSISAGREHPRGVEIFWPEQLEKCLENAEVVLLGVSTD...................................................................................................... 82
41 -11.100d1z82a1 c.2.1.0 (A:2-166) automated matches {Thermotoga maritima [TaxId: 243274]}  ali model 3D-neighbors follow..  11  1..EMRFFVLGAGSWGTVFAQMLHENGE---VILWARRKEIVDLINVSRATNDLEEIKKEDILVIAIPVQYIREHLLRLPVKPSMVL..................................................................................... 95
42 -11.100d2cvza2 c.2.1.6 (A:2-157) Hydroxyisobutyrate dehydrogenase {Thermus thermophilus [TaxId: 274]}  ali model 3D-neighbors follow..  16  2....KVAFIGLGAMGYPMAGHLARR-FPTLVWNRTFEKALRHQEEFGSEAVPLERVAEARVIFTCLPTTREVYEVAEALYPYLRTYWVDATSGEPEASRRLAERLREKG.............................................................. 107
43 -11.000d2izza1 c.2.1.0 (A:1-164) automated matches {Human (Homo sapiens) [TaxId: 9606]}  ali model 3D-neighbors follow..  14  1...MSVGFIGAGQLAFALAKGFTAAGVLAAHKIMLATVSALRKMGVKLTPHNKETVQHSDVLFLAVKPHIIPFILDESCAAGVTISSIEKKLSAFRPAPRVIRCMTNTPVVV........................................................... 128
44 -11.000d1yjqa2 c.2.1.6 (A:1-167) Ketopantoate reductase PanE {Escherichia coli [TaxId: 562]}  ali model 3D-neighbors follow..  12  1...MKITVLGCGALGQLWLTALCKQ-GHEVQGWLRVPQPYCSIFNESLTANDPDFLATSDLLLVTLKAWQ----VSDAVKSLASTLPVTTPILLIHNGMGTIEELQNIQQPL........................................................... 113
45 -10.900d1x7da_ c.2.1.13 (A:) Ornithine cyclodeaminase {Pseudomonas putida [TaxId: 303]}  ali model 3D-neighbors follow..  8  130....KMALIGNGAQSEFQALAFHKHLGIEEIVAYDTDPLATAKLTIRRASSVAEAVKGVDIITTVTADKAYATITPDMLEPGMHLNAVGGDCPGKTELHADVLRNAR................................................................ 243
46 -10.800d1sc6a1 c.2.1.4 (A:108-295) Phosphoglycerate dehydrogenase {Escherichia coli [TaxId: 562]}  ali model 3D-neighbors follow..  11  42ARGKKLGIIGYGHIGT---QLGILAESLGMYVYFYDIENKLPLGNATQVQHLSDLLNMSDVVSLHVP-----------ENPSTKNMMGAKEISLMKPGSLLINASRGT---------------------VVDIPALADALASKHLAGAAI..................... 156
47 -10.700d2v6ba1 c.2.1.0 (A:22-164) automated matches {Deinococcus radiodurans [TaxId: 1299]}  ali model 3D-neighbors follow..  14  1...MKVGVVGTGFVGSTAAFALVLRGSCSELVLVDRDEDRAQAEAERVWHGGHSELADAQVVILTA......................................................................................................... 75
48 -10.600d4dlla1 c.2.1.0 (A:29-190) automated matches {Polaromonas sp. [TaxId: 296591]}  ali model 3D-neighbors follow..  7  2.YARKITFLGTGSMGLPMARRLCEA-ALQVWNRTPARAASLAALGATIHEQARAAARDADIVVSMLENGAVVQ----------DVLFAQGVAAAMKPGSLFLDMASITPREARDHAARLGALGIAHLDTPVSGGTVGA................................. 129
49 -10.500d3g0oa1 c.2.1.0 (A:6-169) automated matches {Salmonella typhimurium [TaxId: 602]}  ali model 3D-neighbors follow..  14  1..DFHVGIVGLGSMGMGAARSCLRA-GLSTWGA-QACANLLAEGACGAAASAREFAGVVDALVILVVNAAQVRQV---------LFGEDGVAHLMKPGSAVMVSSTISSADAQEIAAALTALNLNMLDAPVSGGAVKA................................. 129
50 -10.500d3fefa1 c.2.1.0 (A:7-171) automated matches {Bacillus subtilis [TaxId: 1423]}  ali model 3D-neighbors follow..  15  1LDQIKIAYIGGGSQGSLMSDLSIDERMSGTVALYDLDFEAAQRWRYEAVSTLKKALSAADIVIISI......................................................................................................... 81
51 -10.400d1gdha1 c.2.1.4 (A:101-291) D-glycerate dehydrogenase {Hyphomicrobium methylovorum [TaxId: 84]}  ali model 3D-neighbors follow..  13  45LDNKTLGIYGFGSIGQALAKRAQGF-DMDIDY-HRASSSDEASYQATFHDSLDSLLSVSQFFSLNAP-----------STPETRYFFNKATIKSLPQGAIVVNTARGD---------------------LVDNELVVAALEAGRLAYAGF..................... 163
52 -10.400d1t2da1 c.2.1.5 (A:1-150) Lactate dehydrogenase {Malaria parasite (Plasmodium falciparum) [TaxId: 5833]}  ali model 3D-neighbors follow..  16  2.PKAKIVLVGSGMIGGVMATLIVQKNLGDVVLFTSHTNVMAYSNCKVSGSNTYDDLAGADVVIVTA......................................................................................................... 79
53 -10.400d1ygya1 c.2.1.4 (A:99-282) Phosphoglycerate dehydrogenase {Mycobacterium tuberculosis [TaxId: 1773]}  ali model 3D-neighbors follow..  13  42IFGKTVGVVGLGRIGQLVAQRIAAF-GAYVVAYDPYVSPARAAQLGIELLSLDDLLARADFISVHLP-----------KTPETAGLIDKEALAKTKPGVIIVNAARGG---------------------LVDEAALADAITGGHVRAAGL..................... 158
54 -10.400d5bsea1 c.2.1.0 (A:3-169) automated matches {Medicago truncatula [TaxId: 3880]}  ali model 3D-neighbors follow..  9  6ADSYTLGFIGAGKMAESIAKGAVRSGVLSPSRIKPARRTAFESIGITVLSSNDDVVRDSNVVVFSVKP----QLLKDVVLKLKPLLTKDKLLVSVAAGIKMKDLQEWAGHERFI......................................................... 121
55 -10.300d2x5oa1 c.5.1.0 (A:1-93) automated matches {Escherichia coli [TaxId: 668369]}  ali model 3D-neighbors follow..  16  3YQGKNVVIIGLGLTGLSCVDFFLARG----PRVMDTRMTPPGLDKLPEAVERDEWLMAADLIVASPGIALAHPSLSAAADAGIEIV..................................................................................... 92
56 -10.300d2csua1 c.2.1.8 (A:1-129) Acetate-CoA ligase alpha chain, AcdA, N-terminal domain {Pyrococcus horikoshii [TaxId: 53953]}  ali model 3D-neighbors follow..  10  6FNPKGIAVIGAKKLGYEVFKNLKEYKKGKVYPV---NIKEEEVQGVKAYKSVKDIPDEIDLAIIVVPKRFVKDTLIQCGEKGVKVIITAGFGETGEEGKELVEIAHKYGMRI........................................................... 124
57 -10.300d3nepx1 c.2.1.0 (X:22-163) automated matches {Salinibacter ruber [TaxId: 309807]}  ali model 3D-neighbors follow..  19  1...MKVTVIGAGNVGATVAECVARQDVAKEVVMVDIKDGMPQFDTRVTGTNDYGPTEDSDVCIITA......................................................................................................... 77
58 -10.200d3ws7a1 c.2.1.0 (A:1-161) automated matches {Pyrobaculum calidifontis [TaxId: 410359]}  ali model 3D-neighbors follow..  11  1...MRVGFIGLGIMGGPMATHLLKA-LAAVYNRTREKTKPFAEAGVYVAESPADLAKRVDVVIVMVSDAPDVEQV---------LFGPSGVVEGARPGLIVVDMSTNSPDWARKFAERLAQYGIEFLDAPVTGGQKGA................................. 127
59 -10.200d4m1qa1 c.2.1.0 (A:3-144) automated matches {Bacillus selenitireducens [TaxId: 439292]}  ali model 3D-neighbors follow..  16  2.KTSRVVIIGTGAVGSSYAFSMINQNVTDEMVLIDLDKRKTEGDAMKVWAGDYGDCKSADIVVITA......................................................................................................... 78
60 -10.200d2gf2a1 c.2.1.0 (A:41-201) automated matches {Human (Homo sapiens) [TaxId: 9606]}  ali model 3D-neighbors follow..  10  1....PVGFIGLGNMGNPMAKNLMKH-PLIIYDVFPDACKEFQDAGEQVVSSPADVAEKADRIITMLPTSINAIEA---------YSGANGILKKVKKGSLLIDSSTIDPAVSKELAKEVEKMGAVFMDAPVSGGVGAA................................. 126
61 -10.200d1y81a1 c.2.1.8 (A:6-121) Hypothetical protein PF0725 {Pyrococcus furiosus [TaxId: 2261]}  ali model 3D-neighbors follow..  11  3....KIALVGASKNPAKYGNIILKDLLSKGFEVLPVNPNYDEIEGLKCYRSVRELPKDVDVIVFVVPPKVGLQVAKEAVEAGFKKLWFQP-----AESEEIRRFLEKAGVEY........................................................... 106
62 -10.100d1llda1 c.2.1.5 (A:7-149) Lactate dehydrogenase {Bifidobacterium longum, strain am101-2 [TaxId: 216816]}  ali model 3D-neighbors follow..  15  1..PTKLAVIGAGAVGSTLAFAAAQRGIAREIVLEDIAKERVEPTVSIDGSDDPEICRDADMVVITA......................................................................................................... 77
63 -10.100d1vm6a3 c.2.1.3 (A:1-96,A:183-214) Dihydrodipicolinate reductase {Thermotoga maritima [TaxId: 2336]}  ali model 3D-neighbors follow..  14  1...MKYGIVGYGRMGQEIQKVFSEKGHELVLKVDV---------------NGVEELDSPDVVIDFSSPEALPKTVDLCKKYRAGLVL----TTALKEEHLQMLRELSKEVPVVQAYXSRTVFAIGALKAAEFLVG.................................... 115
64 -10.000d1hyha1 c.2.1.5 (A:21-166) L-2-hydroxyisocapronate dehydrogenase, L-HICDH {Lactobacillus confusus [TaxId: 1583]}  ali model 3D-neighbors follow..  19  3....KIGIIGLGNVGAAVAHGLIAQGVADDYVFIDANEAKVKEAHGNIVINDWAALADADVVISTL......................................................................................................... 77
65 -10.000d5je8a1 c.2.1.0 (A:1-163) automated matches {Bacillus cereus [TaxId: 226900]}  ali model 3D-neighbors follow..  11  3....KIGFIGLGNMGLPMSKNLVKS-TVYGVDLNKEAEASFEKEGGIIGLSISKLAETCDVVFTSLPSPRAVEAV---------YFGAEGLFENGHSNVVFIDTSTVSPQLNKQLEEAAKEKKVDFLAAPVSGGVIGA................................. 128
66 -10.000d1dlja2 c.2.1.6 (A:1-196) UDP-glucose dehydrogenase (UDPGDH) {Streptococcus pyogenes [TaxId: 1314]}  ali model 3D-neighbors follow..  10  1...MKIAVAGSGYVGLSLGVLLSLQNEVTIVDILPSKVDKSKQLSIKATLDSKAAYKEAELVIIATPTNYNSRINYFDTQH---VETVIKEVLSVNSHATLIIKSTIPIGFITEMRQKFQTDRIIFSPEFLRESKA................................... 148
67 -9.980d1gr0a1 c.2.1.3 (A:14-200,A:312-367) Myo-inositol 1-phosphate synthase {Mycobacterium tuberculosis [TaxId: 1773]}  ali model 3D-neighbors follow..  15  1.TEVRVAIVGVGNCASSLVQGVEYYYNADDPGLMHVRPYHVRDVKFVAAFDVDAKKVGFDLSDAIFASENNTIKIADVAPTNVIVQRGPTLDGIGKYYADTIELSDAEPV------------DVVQALKEAKVDVLVSYLPVGSEEADKFY.................... 144
68 -9.970d1bgva1 c.2.1.7 (A:195-449) Glutamate dehydrogenase {Clostridium symbiosum [TaxId: 1512]}  ali model 3D-neighbors follow..  14  34LVGKTVALAGFGNVAWGAAKKLAEL-GAKAVTLSGPDQDYADKFGVQFFPGEKPWGQKVDIIMCATQNDVDLEQAKKIVANNVKYYIEVANMPTTNEALRFLMQQPN................................................................ 169
69 -9.900d1gtma1 c.2.1.7 (A:181-419) Glutamate dehydrogenase {Pyrococcus furiosus [TaxId: 2261]}  ali model 3D-neighbors follow..  18  30LKGKTIAIQGYGNAGYYLAKIMSEDFGMKVVAVSDEHGSVKDFPGATNITNEELLELEVDVLAPAAIEEVITKKNADNIKA--KIVAEVANGPVTPEADEILFE................................................................... 152
70 -9.890d1omoa_ c.2.1.13 (A:) Archaeal alanine dehydrogenase {Archaeoglobus fulgidus [TaxId: 2234]}  ali model 3D-neighbors follow..  12  127....VFGFIGCGTQAYFQLEALRRVFDIGEVKAYDVREKAAKKFGISASVQPAEEASRCDVLVTTTPSRKPV-VKAEWVEEGTHINAIGADGPGKQELDVEILKKAK................................................................ 235
71 -9.880d1jaya_ c.2.1.6 (A:) Coenzyme F420H2:NADP+ oxidoreductase (FNO) {Archaeoglobus fulgidus [TaxId: 2234]}  ali model 3D-neighbors follow..  17  1...MRVALLGTGNLGKGLALRLATLGHEIVVGSRREEKAEAKAAEYITGMKNEDAAEACDIAVLTIPWEHAIDTARDLKNILREKIV.................................................................................... 93
72 -9.870d4ajjc1 c.2.1.0 (C:1-159) automated matches {Norway rat (Rattus norvegicus) [TaxId: 10116]}  ali model 3D-neighbors follow..  13  17VPQNKITVVGVGAVGMACAISILMKDLADELALVDVIEDKLKKTPKIVSSKDYSVTANSKLVIITA......................................................................................................... 95
73 -9.830d1evya2 c.2.1.6 (A:9-197) Glycerol-3- phosphate dehydrogenase {Trypanosome (Leishmania mexicana) [TaxId: 5665]}  ali model 3D-neighbors follow..  11  5LYLNKAVVFGSGAFGTALAMVLSKKCNEEEVRLVNEKRENVLFLKITFTSDVEKAYNGAEIILFVIPTQ...................................................................................................... 88
74 -9.750d3fi9a1 c.2.1.0 (A:2-147) automated matches {Porphyromonas gingivalis [TaxId: 431947]}  ali model 3D-neighbors follow..  13  3LTEEKLTIVGAGMIGSNMAQTAAMMRLTPNLCLYDPFAVGLEGVAETFTSDIKEALTDAKYIVSSGGAPRKEGMTRDLLKGNAEIAAQKDIKSYCPDCKHVIIIFNPADITGLVT........................................................ 133
75 -9.740d3k96a1 c.2.1.0 (A:3-180) automated matches {Coxiella burnetii [TaxId: 227377]}  ali model 3D-neighbors follow..  17  2FKH-PIAILGAGSWGTALALVLARKGESDHVDEMQAEGVNNRYLPLKAYCDLKASLEGVTDILIVVPSF...................................................................................................... 84
FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Li W, Godzik A. Discovering new genes with advanced homology detection. Trends Biotechnol. 2002 Aug;20(8):315-6.