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Query: d3kx2a1 c.37.1.19 (A:1-270) Pre-mRNA splicing factor DEAH RNA helicase Prp43 {Baker`s yeast (Saccharomyces cerevisiae) [TaxId: 559292]}, from SCOP207

Results of FFAS03 search in SCOP207
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MGSKRRFSSEHPDPVETSIPEQAAEIAEELSKQHPLPSEEPLVHHDAGEFKGLQRHHTSAEEAQKLEDGKINPFTGREFTPKYVDILKIRRELPVHAQRDEFLKLYQNNQIMVFVGETGSGKTTQIPQFVLFDEMPHLENTQVACTQPRRVAAMSVAQRVAEEMDVKLGEEVGYSIRFENKTSNKTILKYMTDGMLLREAMEDHDLSRYSCIILDEAHERTLATDILMGLLKQVVKRRPDLKIIIMSATLDAEKFQRYFNDAPLLAVPGRLast
1 -107.000d3kx2a1 c.37.1.19 (A:1-270) Pre-mRNA splicing factor DEAH RNA helicase Prp43 {Baker`s yeast (Saccharomyces cerevisiae) [TaxId: 559292]}  ali model 3D-neighbors  100  1MGSKRRFSSEHPDPVETSIPEQAAEIAEELSKQHPLPSEEPLVHHDAGEFKGLQRHHTSAEEAQKLEDGKINPFTGREFTPKYVDILKIRRELPVHAQRDEFLKLYQNNQIMVFVGETGSGKTTQIPQFVLFDEMPHLENTQVACTQPRRVAAMSVAQRVAEEMDVKLGEEVGYSIRFENKTSNKTILKYMTDGMLLREAMEDHDLSRYSCIILDEAHERTLATDILMGLLKQVVKRRPDLKIIIMSATLDAEKFQRYFNDAPLLAVPGR 270
2 -53.000d1a1va1 c.37.1.14 (A:190-325) HCV helicase domain {Human hepatitis C virus (HCV), different isolates [TaxId: 11103]}  ali model 3D-neighbors follow..  20  3.......................................................................................................AVPQSFQVAHLHAPTGSGKSTKVPAAYAA------QGYKVLVLNPSVAATLGFGAYMSKAHGVDPNIRTGVRTITTG-----SPITYSTYGKFLAD--GGCSGGAYDIIICDECHSTDATSILGIGTVLDQAETAGARLVVLATAT..................... 135
3 -36.600d1yksa1 c.37.1.14 (A:187-324) YFV helicase domain {Yellow fever virus [TaxId: 11089]}  ali model 3D-neighbors follow..  21  1........................................................................................................MLKKGMTTVLDFHPGAGKTRRFLPQILAECA--RRRLRTLVLAPTRVVLSEMKEAFH-------GLDVKFHTQFSAHGSGREVIDAMCHATLTYRMLEPTRVVNWEVIIMDEAHFLDPASIAARGWAAHRA-RANESATILMTAT..................... 136
4 -35.300d5y4za1 c.37.1.14 (A:178-481) automated matches {Zika virus (strain mr 766) [TaxId: 64320]}  ali model 3D-neighbors follow..  18  5.......................................................................................................SMLKKKQLTVLDLHPGAGKTRRVLPEIVRE--AIKKRLRTVILAPTRVVAAEMEEALR-------GLPVRYTTAVNVTHSGTEIVDLMCHATFTSRLLQPIRVPNYNLNIMDEAHFTDPSSIAARGYISTRV-EMGEAAAIFMTATPPGTRDAFPDSNSPIMD.... 158
5 -14.400d1wp9a1 c.37.1.19 (A:1-200) putative ATP-dependent RNA helicase PF2015 {Pyrococcus furiosus [TaxId: 2261]}  ali model 3D-neighbors follow..  14  1.....................................................................................MVLRRDLIQPRIYQEVIYAKCKETNCLIVL-PTGLGKT--LIAMMIAEYRLTKYGGKVLMLAPTKPLVLQHAESFRRLFNLPPEKIVALT----SKAWARAKVIVATPQTIENDLLAG-SLEDVSLIVFDEAH-RAVGNYAYVFIAREYKRQAKNPLVIGLTAS-TPEKIMEVINNLGIEHIEYR 188
6 -14.300d2fz4a1 c.37.1.19 (A:24-229) DNA repair protein RAD25 {Archaeoglobus fulgidus [TaxId: 2234]}  ali model 3D-neighbors follow..  17  47......................................................................SNGIEFVDNAADPIPTPYFDAEISLRDYQEKALERWLVDKRGCIVLPTGSGKTH----VAMAAINELSTPTLI-------VPTLALAEQWKERLGIFGEEYVG---EFSGRIKELKPLTVSTYDSAYVN--AEKLGNRFMLLIFDEVHHLPAES------YVQIAQMSIAPFRLGLTATFE................... 206
7 -13.800d1gkub1 c.37.1.16 (B:6-250) Helicase-like "domain" of reverse gyrase {Archaeoglobus fulgidus [TaxId: 2234]}  ali model 3D-neighbors follow..  14  40...............................................................................................RAIQKMWAKRILRKESFAATAPTGVGKTS----GLAMSLFLALKGKRCYVIFPTSLLVIQAAETIRK-IGYYHGRIPKREKENFMQNLRNFKIVITTTQFLSKHYRE---LGHFDFIFVDDVDKASKNVDKLLHLLTKSWVGEARGCLMVSTATAKKGKKAELFRQLLNFDI... 226
8 -13.800d2p6ra3 c.37.1.19 (A:1-202) Hel308 helicase {Archaeoglobus fulgidus [TaxId: 2234]}  ali model 3D-neighbors follow..  16  26..............................................................................................LFPPQAEAVEKVFSGKNLLLAMPTAAGKTLLAEMAMVRE---AIKGGKSLYVVPLRALAGEKYESFKEKIGLRIGISTG-DYESRDEHLGDCDIIVTTDSLIRNR---ASWIKAVSCLVVDEIHKRGATLEILVTKMRRM---NKALRVIGLSATAPNVTEIAEWLDADYYVSDWR 202
9 -13.100d3bera_ c.37.1.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}  ali model 3D-neighbors follow..  21  27.................................................................................EACDQLGWTKPTKI---QIEAIPLALQGRDIIGLAETGSGKTGAFALPILNALLETPQRLFALVLTPTRELAFQISEALGSSIGVQSAVIVG-----SLALAKKPHIIIATPGRLIDHLENTKNLRALKYLVMDEA-DRILNMDFETEVDKILKVIPRDRKTFLFSATMKVQKLQRAALKNPV...... 214
10 -13.000d2pl3a1 c.37.1.0 (A:47-278) automated matches {Human (Homo sapiens) [TaxId: 9606]}  ali model 3D-neighbors follow..  19  50..................................................................................................QKQTIGLALQGKDVLGAAKTGSGKTLALEALYRLQWTSTDGLGVLIISPTRELAYQEVLRKVGKNHDFSAGLIIG-DLKHEAERINNINILVCTPGRLLQHMDETVHATDLQMLVLDEA-DRILDMGFADTMNAVIENLPKKRQTLLFSATQTKS................. 213
11 -12.800d1qdea_ c.37.1.19 (A:) Initiation factor 4a {Baker`s yeast (Saccharomyces cerevisiae) [TaxId: 4932]}  ali model 3D-neighbors follow..  16  37..................................................................................................QQRAIMPIIEGHDVLAQAQSGTGKTGTFSIAALQRIDTSVKAPQALMLAPTRELALQIQKVV-MALAFHMDIKVGTSFVEDAEGLRDAQIVVGTPGRVFDNIQRRRRTDKIKMFILDEA-DEMLSSGFKEQIYQIFTLLPPTTQVVLLSATMDVLEVTTKFMRNPV...... 208
12 -12.700d1rifa_ c.37.1.23 (A:) DNA helicase UvsW {Bacteriophage T4 [TaxId: 10665]}  ali model 3D-neighbors follow..  69.................................................KKFCDNFGYKAWIDPQINEKEELSRKDFDEWLSKLEIYSGNKRIEPHWYQKDAVFEGLVNRRRILNLPTSAGRSLIQALLARYYLENYEGKILI-------VPTTALTTQMADDFVDYRLKKIGGGASKDDKYKNDAPVVVGTWQTVVKQP--KEWFSQFGMMMNDECHL--ATGKSISSIISGLNNCMFKFGLSGSLRDGKANIMQYVGMFGEIFK.... 281
13 -12.700d2oxca_ c.37.1.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}  ali model 3D-neighbors follow..  16  28..................................................................................................QLKAIPLGRCGLDLIVQAKSGTGKTCVFSTIALDSLVLENLSTQILILAPTREIAVQIHSVITAIGIKMEGLECGTPLSQDKTRLKKCHIAVGSPGRIKQLIELDYNPGSIRLFILDEA-DKLLEEGSFQEQINWIYSSLPSKQMLAVSATYFLANALTKYMRDPT...... 201
14 -12.400d3iuya1 c.37.1.0 (A:213-439) automated matches {Human (Homo sapiens) [TaxId: 9606]}  ali model 3D-neighbors follow..  19  32.................................................................................KSIIRVGILKPTPI---QSQAWPIILQGIDLIVVAQTGTGKTLSMPGFI-PISREQRNGPGMLVLTPTRELALHVEAECSKYSYKGLGRNRNGQIE---DISKGVDIIIATPGRLNDLQMNNSNLRSITYLVIDEA-DKMLDMEFEPQIRKILLDVRPDRQTVMTSATWTVRQLALSYLKDPM...... 223
15 -12.200d3dkpa1 c.37.1.0 (A:139-378) automated matches {Human (Homo sapiens) [TaxId: 9606]}  ali model 3D-neighbors follow..  17  40.................................................................................QNILDAGFQMPTPI---QMQAIPVMLHGRELLASAPTGSGKTLAFSIPILMQLKQPANKGFRALISPTRELASQILIKISEGTGFRIHMIHK-AKKFGPKSSKKFDILVTTPNRLIYLLKQDPDLASVEWLVVDES-DKLFEDG--TGFRDQLASTSHKVRRAMFSATFDVEQWCKLNLDNVISVSIG. 239
16 -12.100d1q0ua_ c.37.1.19 (A:) Probable DEAD box RNA helicase YqfR {Bacillus stearothermophilus [TaxId: 1422]}  ali model 3D-neighbors follow..  18  28..................................................................................................QERIIPGALRGESMVGQSQTGTGKTHAYLLPIMEKIKPERAEVQAVITAPTRELATQIYHETLK------GTDKQKALE---KLNVQPHIVIGTPGRINDFIREQADVHTAHILVVDEA-DLMLDMGFITDVDQIAARMPKDLQMLVFSATIKLKPFLKKYMENPT...... 204
17 -12.000d4ct4b1 c.37.1.0 (B:95-301) automated matches {Human (Homo sapiens) [TaxId: 9606]}  ali model 3D-neighbors follow..  19  29..................................................................................................QEESIPIALSGRDILARAKNGTGKSGAYLIPLLERLDLKKDNIQAMVIVPTRELALQVSQICIQ-MATTGGTNLRDDIM---RLDDTVHVVIATPGRILDLIKKGVKVDHVQMIVLDEA-DKLLSQDFVQIMEDIILTLPKNRQILLYSATFSVQKFMNSHLQKPY...... 202
18 -11.900d1ls1a2 c.37.1.10 (A:89-295) GTPase domain of the signal sequence recognition protein Ffh {Thermus aquaticus [TaxId: 271]}  ali model 3D-neighbors follow..  18  1...................................................................................................EARLPVLKDRNLWFLVGLQGSGKTTTAAKLALYYK-GKGRRPLLVAADTQRPAAREQLRLLGEKVGVPV---------LEVMDGESPE--------IRRRVEEKARLEARDLILVDTAGRLQIDEPLMGELARLKEVLGPDEVLLVLDAMTGQEALSVARAFDEKVGVTG. 153
19 -11.800d5gvra_ c.37.1.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}  ali model 3D-neighbors follow..  18  26.................................................................................RGLKKKGIHHPTPI---QIQGIPTILSGRDMIGIAFTGSGKTLVLPVIMFCLEFSKREGPYGLIICPSRELARQT-HGILEYYCRLLQEDSSPLLR--ETIRHGVHMMVATPGRLMDLLQKKMSLDICRYLALDEA-DRMIDMGFEGDIRTIFSYFKGQRQTLLFSATMKIQNFAKSALVKPVTINVGR 232
20 -11.700d2z0ma1 c.37.1.0 (A:1-192) automated matches {Sulfolobus tokodaii [TaxId: 111955]}  ali model 3D-neighbors follow..  19  21..................................................................................................QSKTIPLMLQGKNVVVRAKTGSGKTAAYAIPILELGM------KSLVVTPTRELTRQVASHI-RDIGRYMDTKVGMPYKAQINRVRNADIVVATPGRLLDLWSKGVDLSSFEIVIIDEA-DLMFEMGFIDDIKIILAQTSNRKITGLFSATIEIRKVVKDFITNYE...... 186
21 -11.500d1t6na_ c.37.1.19 (A:) Spliceosome RNA helicase BAT1 (UAP56) {Human (Homo sapiens) [TaxId: 9606]}  ali model 3D-neighbors follow..  18  28..................................................................................................QHECIPQAILGMDVLCQAKSGMGKTAVFVLATLQQLEPVTGQVSVLVMCHTRELAFQISKEYERKVAVFFGG-LSIKKDEEVLKKNCPHIVVGTPGRILALARNKSNLKHIKHFILDECDKMLEQLDMRRDVQEIFRMTPHEKQVMMFSATLEIRPVCRKFMQDPM...... 203
22 -11.400d1w36d1 c.37.1.19 (D:2-360) Exodeoxyribonuclease V alpha chain (RecD) {Escherichia coli [TaxId: 562]}  ali model 3D-neighbors follow..  17  153..................................................................................................QKVAAAVALTRRISVISGGPGTGKTTTVAKLLALIQMADGERCRIRLAAPTGKAA----ARLTESLGKALRQ-----LPLTDEQKKRIPEDASTLHRLLGAQPGSQRLRHLDVLVVDEA--SMIDLPMMSRLIDAL---PDHARVIFLG---DRDQLASVEAGAVLGDI... 312
23 -11.300d2i4ia3 c.37.1.0 (A:168-406) automated matches {Human (Homo sapiens) [TaxId: 9606]}  ali model 3D-neighbors follow..  20  26.................................................................................GNIELTRYTRPTPV---QKHAIPIIKEKRDLMACAQTGSGKTAALPILSQIYSDGRKQYPISLVLAPTRELAVQIARKFSYRSRVRPGADIGQQIR---DLERGCHLLVATPGRLVDMMERGKGLDFCKYLVLDEA-DRMLDMGFEPQIRRIVMPPKGVRHTMMFSATFEIQMLARDFLDEYIFLAVG. 239
24 -11.200d3peya1 c.37.1.0 (A:91-286) automated matches {Baker`s yeast (Saccharomyces cerevisiae) [TaxId: 4932]}  ali model 3D-neighbors follow..  19  29........................................................................................QERALPLL--------LHNPPRNMIAQSQSGTGKTAAFSLTMLTRVNPEDASPQAICLAPSRELARQTLEEMGKFTKITSQLIVPDSFEKNKQINAQVIV---TPGTVLDLMRRKLQLQKIKIFVLDEADNMLDQQGLGDQCIRVKRFLPKDTQLVLFSATFADA................. 187
25 -11.100d3mwja_ c.37.1.0 (A:) automated matches {Thermus thermophilus [TaxId: 262724]}  ali model 3D-neighbors follow..  18  14.................................................................................EALHGRGLTTPTPI---EAAALPLALEGKDLIGQARTGTGKTLAFALPIAERSQERGRKPRALVLTPTRELALQVASELTA------GTGYGKQKE---ALLRGADAVVATPGRALDYLRQGVDLSRVEVAVLDEA-DEMLSMGFEEEVEALLSATPPSRQTLLFSATLWAKRLAERYMKNPV...... 201
26 -10.400d1ye8a1 c.37.1.11 (A:1-178) Hypothetical kinase-like protein Aq_1292 {Aquifex aeolicus [TaxId: 63363]}  ali model 3D-neighbors follow..  14  3...............................................................................................................IIITGEPGVGKTTLVKKIV--ERLGKRAIGFWGFRIITTEGKKKIFSSKFFTSKKLVGSYGVNVQYFEELAIP-----------ILERAYREAKKDRRKVIIIDEIGKMELFSKKFRDLVRQIMHDPNVNVVATIPIRDVHPLVKEI-PGAVLIELT.. 161
27 -10.200d2yhsa2 c.37.1.10 (A:285-495) automated matches {Escherichia coli K-12 [TaxId: 83333]}  ali model 3D-neighbors follow..  15  11..............................................................................................................VILMVGVNGVGKTTTIGKLARQFE-QQGKSVMLAAGDTFRAAAV--------EQLQVWGQRNNIPVIAQHTGADSASVIF--------DAIQAAKARNIDVLIADTAGRLQNKSHLM--VMKKLDVEAPHEVMLTIDASTGQNAVSQAKLFHEAVGLTG. 158
28 -9.910d2i3ba1 c.37.1.11 (A:1-189) Cancer-related NTPase, C1orf57 {Human (Homo sapiens) [TaxId: 9606]}  ali model 3D-neighbors follow..  12  2.............................................................................................................RHVFLTGPPGVGKTTLIHKAS----------------EVLKSSGVPVDGFYTEEVRQG-GRRIGFDVVTLSGTRGPLSRVGLEPALPVLRNADCSSGPGQRVCVIDEIGKMELFSQLFIQAVRQTLSTPGTIILGTIPVP..................... 146
29 -9.620d1oywa2 c.37.1.19 (A:1-206) RecQ helicase domain {Escherichia coli [TaxId: 562]}  ali model 3D-neighbors follow..  21  30..................................................................................................QEEIIDTVLSGRDCLVVMPTGGGKSLQIPALLLNSPLISLMKDQVDQLQANGVAAACLNSTQTREQQLEV---------MTGCRTGQIRLLYIAPERLMLDNFLEHLAHNPVLLAVDEAH-HDFRPEYA---LGQLRQRFPTLPFMALTATADDT................. 187
30 -9.490d2gk6a1 c.37.1.19 (A:295-324,A:416-702) Upf1 {Human (Homo sapiens) [TaxId: 9606]}  ali model 3D-neighbors follow..  17  87..............................................................................................LNHSQVYAVKTVLQRPLSLIQGPPGTGKTVTSATIVY--HLARQGNGPVLVCAPSNIAVDQLTEKIHQT--VRLCAALHNQIRNMDSMPELQKLQQLKDETAERELLMNADVMQFRSILIDESTQ-ATEPECMVPVVLGLVGDHCQLGPVVMCKKLSQSLFERLV........... 305
31 -9.050d1wb9a2 c.37.1.12 (A:567-800) DNA repair protein MutS, the C-terminal domain {Escherichia coli [TaxId: 562]}  ali model 3D-neighbors follow..  12  3...................................................................................CPTFIDKPGIRITEGRHPVVEQVPQRRMLIITGPNMGGKSTYMRQTALIALMAY-----IGSYVPAQKVEIGPIDRIFTRVGAADDLASGRSTFMVEMTETANILHNATEYSL---------------VLMDEIGRGTSTYD-LAWACAENLANKIKALTLFATHYFELTQLPEKMEGVANVHLD.. 182

FFAS is supported by the NIH grant R01-GM087218-01
1 4 6 2 1 7   jobs submitted since Jan 1, 2011
Comments and questions to: webmaster

Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Pawlowski K, Jaroszewski L, Rychlewski L, Godzik A. Sensitive sequence comparison as protein function predictor. Pac Symp Biocomput. 2000;:42-53.