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Query: TM0008 TM0008 281889 Crystal|NMR-2001-04-01, from T.maritima

Results of FFAS03 search in COG1018
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MFIELSYPIEERMLTYPDNPPDYFEPKSRIEQGDAANTMMIHHFSHTGTHVDAPYHFCEEGWTLDQIPLEYFIFEKPLLVDREKKPMELFTIEDIEELDLNGVDLLMFRSGFAKLRRTDPATYRYMFPGISKELARFLRESVLSLKAVMLDFLSADPIVLGEKENYPAHRWLLSKKFSSKRPIIIFEDVNLEPVAGKKIKRVIALPLRFKGLDGGPVSVLAEVELast
1 -80.900[R] COG1878 Predicted metal-dependent hydrolase  ali follow..  31  6RYFDLTAPIYPYMPVWPSNPPVELKPIVTVPK-DGYLAEIIEASTHTGTHIDAPAHMIEGGTTVDDLDLASLIGTGYCLKVLP--DGHTIRSTHLAEKGIYNNSILLIETGWYKKRG-YTREFQYDFPGLSEDAADFLIQK--HVKAVGIDTLGIEP---YENTDFRVHKKLLRSG------IPIIEDLGLDSLEEGRPYLIIALPLRLKGTSGSMARVVAAET 217
2 -6.420[C] KOG0535 Sulfite oxidase, molybdopterin-binding component  ali follow..  2................PWSQEPQRHALLKPASKRPFNAEPPIGLLAEQFYTPNELFYVRNHLPVPVINPEDY------LEIEGGAKDKTLTLDGIKALPKHSVTAAIMCGGNRRSEMTKVKA---------VKGLSWGAGAVGNAKWSGARLCDI--LREQGVQPDETKHVIFEGADLDPTSHPYGASIPLAKALDPRGDVILAYEMNLSRDHGFPIRVIV... 193
3 -6.040[J] COG1727 Ribosomal protein L18E  ali follow..  13  49...................................INLYKIDKFAKDGDVIVVPGSVLGVGKITKKVTIGAVHFSRAATEKLVRSGCAFMSLSDVAKANPKGTNVKIMR................................................................................................................... 122
4 -4.920[J] KOG1416 tRNA(1-methyladenosine) methyltransferase, subunit GCD10  ali follow..  80..........................................................KTNQELNDCRGNQLMTQEEIDELRANIKAGGLRAEEAIKQLTNSSKTFEQKTLFAKYVTRKGEKYLQRFQVLRPCVEVMIEHDPYKILDLTAECIS---------------LMLTLGNVKPGGRYLVVDETG----------MFLGSLIDRVAGDCKITLV..... 222
5 -4.770[G] KOG0523 Transketolase  ali follow..  535............................AMRISALSEAGVIYVMTHDSIGLDGPTH-----QPIEHIASFRAMPNTLMFRPADGNETAGAYKIAVTKRK-NKPDVILIGTGSE--------------LEIAAQAAEVLRKDGKTVRVVSFVCWEL------DEQSDEYKESVLPSDV---SARVSIEAASTFGWGKIVGGKGKSIGINSFGASAPAPLLY.... 736
6 -4.720[E] KOG2964 Arginase family protein  ali follow..  18  170..............SLGGDHTIVLPILRALHRVYGQPISVIHFDSHLDTHGSYFYFASQEGDANIHAGIRTPISSFSDYDDDVDCGFKIIEAREIDDLGIDG-DIDVLDPAFAPATGTPET-------GWSSREMRAILRGLQGLKFVGADLVEVAPAYDVAEITSLAGAQLL................................................... 359
7 -4.680[H] COG0303 Molybdopterin biosynthesis enzyme  ali follow..  11  99.....AVRIMTGAQIPEGADAVVMIELTQAFEENGKSFMSLKRRFQTGDNISKTGEDAQKGSVL--------LTKGTRVTPGVTALLATFGYASVPVV--RKPVVGIIATGTELLNVSDPLEPGKIRNSNASMVYAQAIEAGATPLYLGKISDELDKSFAAVKEAMKKVDFLITTGGVSVGDFDFLPAIYEKLGADVLFNKVAMRPGSLFGLSGNPSACYVGFE 318
8 -4.620[R] KOG1108 Predicted heme/steroid binding protein  ali follow..  68.........................................ELAKFNGEEEGRPLYLALLGSVFDVSRGIKHYGSGCSYNFVGRDASVSFISGDFETYDPETADDV-LKPDDLIGLAGWRDFYQKDYVYKGRVIGRFYDEKGALTTYHHKFLELLEQARDAKRQVEELRARYPGCNIEWSEE---TRVWCTTTSGDGKERSWIGYPRKLYSRGNKSFQCACVPD 251
9 -4.600[L] COG3145 Alkylated DNA repair protein  ali follow..  103.................................EACLINFYTADAKMGLHQD------RDEADFSAPVVSVSLGDDCLFRVGQTTRD-----GATKSFRLKSGDVVVLGGEGRLAFHGVDRIYPSTSALLKNGGRINLTLRR.................................................................................. 200
10 -4.470[R] COG2872 Predicted metal-dependent hydrolases related to alanyl-tRNA synthetase HxxxH domain  ali follow..  15  70........ISHEITPVDGNAALGLKAGDRVRGIIDWDRRYRHMRMHTATHVIANVIEKEAGAQITGNQLGL---DKSRVDFSL----EAFDRDKFAEYEKIANKVITENHPVNLYLVSRKEA--EEKLSRLTTLAKGFSEEISEVRLVEIEGITIEA................................................................... 209

FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Reed JC, Doctor K, Rojas A, Zapata JM, Stehlik C, Fiorentino L, Damiano J, Roth W, Matsuzawa S, Newman R, Takayama S, Marusawa H, Xu F, Salvesen G, Godzik A.; RIKEN GER Group; GSL Members. Comparative analysis of apoptosis and inflammation genes of mice and humans. Genome Res. 2003 Jun;13(6B):1376-88.