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Query: TM0017 TM0017 281898 Purified-2003-03-05, from T.maritima

Results of FFAS03 search in CSGID
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MRMERVVERVAVTGAEAVANAMRQIEPDVVAAYPITPQTPIVEYFARFVADGVVRTEMIPVESEHSAMSAVVGAAAAGARAMTATSANGLALMHEIVYIAASYRLPIVMPVVNRALSGPINIHCDHSDAMAERDSGWIQLFAETNQEAYDFTILAVRLAEHEDVRLPVMVNLDGFILSHGVEPVEFYPDELVKKFVGELKPMYPLLDTEHPVTWGPLDLYDYYFEHKRQQIEAMENVKKVFPEIAKEFEETFGRKYWFVEPYRMEDAEHVMVALGSTNSTIKYVVDELREEGYKVGSLKIWMFRPFPKEQLQELLNGRKSVVVLDRAVSFGAEAPLYEAVKSALYEVAARPMLGSYVYGLGGRDIKPEHIRKAFEDAINGNLIADEQRYLGLRELast
1 -86.000IDP06147 gene: oorA; 2-oxoglutarate-acceptor oxidoreductase subunit OorA [Helicobacter pylori J99] NP_223255 [Helicobacter pylori J99]  ali follow..  19  1......MREIISDGNELVAKAAIEVGCRFFGGYPITPSSDIMHAMSVALPK--CGGHFIQMEDEISGISVSLGASMSGTKSMTASSGPGISLKVEQIGYSFMAEIPLVIADVMRSGPSTGPTRVAQGDVNIHGDFKAVALAPANLEEAYTETVRAFNLAEMLMTPVFLLMDE---TVGHMYGKVQIPDLEEVQKMTINRKEFAGDKKVLNPFFKGYRYHVSGLHHGPIGFPTEDAKIGGDLIDRLFHKIESKQDIINENEEMDLEGTEIVIIAYGSVSLAVKEALKDYKESKQKVGFFRPKTLWPSPAKRLKEIGDKYEKILVIELNK-----GQYLEEIERVMQRK------VHFFGQANGRTISPKQIIAKLKEL................. 375
2 -83.300IDP90568 gene: oorA; 2-oxoglutarate-acceptor oxidoreductase subunit OorA [Campylobacter jejuni subsp. jejuni NCTC 11168] Cj0536 [Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819]  ali follow..  20  1......MREVIATGNVLIAKAAIDCGCKFFGGYPITPSSEIAHELSHMLPAN--DGTFIQMEDEISGISVAIGAAMSGVKSMTASSGPGISLKAEQIGLAFIAEIPLVIVNVMRGGPSTGPTRVAQGDLFTHGDFASIAIAPASLEEAYTETIRAFNLAEKYMTPVFLLMDETVGHMNGKAVLPDLKDIKVYNRKKKDYKPYAAGENEPATLNPFFTGYRYHVTGLHHGDIGFPTEDGVIVKKNMERLIGKIQEDICTYEEYMLDDAEFLIIAYGSVSRSAKEAIQRLREQGIKVGLFRPITLYPVAEKKIAEVVSKFKKVMVSELNM-----GQYLEEIERVT-----SRRDFISLHRANGRPITPSEIIAKVKENI................ 374
3 -82.400IDP90660 pyruvate ferredoxin/flavodoxin oxidoreductase [Campylobacter jejuni subsp. jejuni NCTC 11168] Cj1476c [Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819]  ali follow..  30  2.....GKIMKTMDGNEAAAYAAY-AFTEVAGIYPITPSSPMADYTDMWAAAGKKNLKIVEMQSEAGAAGSVHGSLQAGALTTTYTASQGLLLKIPNMYKIAGQLLPCVIHVAARSLAAQASIFGDHQDIYAARQIGFAMLCSHSVQETMDLAGVAHLAAIKGRVPF--LHFFDGFRTSHEIQKVEVMDYAHFDRLLDREALRNNALNPENPKTRGTAQNDDIYFQTREVSNRFYDALPDVVNEYMQEISKITGREYKPFTYYGHKEPECVIVAMGSVTQALEEVVDYLNAKGEKVGILKVYLYRPFSLKYFFDVMKSVKKIAVLDRTKEPGSLEPLYLDVKSAFYGRENAPVIVGGRYGLSSKDVDPAQMIAVFENLKLDNPKDG......... 389
4 -16.600IDP02743 gene: bfmbAb; 3-methyl-2-oxobutanoate dehydrogenase, beta subunit [Bacillus anthracis str. `Ames Ancestor`] GBAA4383 [Bacillus anthracis str. `Ames Ancestor`]  ali follow..  15  11..............TLAMREEMERDEKVFVLGEDVGKKGGVFKATHGLYDQFGEDRALDTPLAESAIAGVAIGAAMYGMRPIAEMQFADFIMVNQIVSEAAKIRCPITVRAPFGGGVHGALYHSQSVEAMFANQPGLKIVIPSTPYDAKGLLKAAIRDED----PVLFFEHKRAYRLIKGEVPEDDYVLPIGKADVKR------------------------------------------------------------------EGDDITVITYGLCVHFALQAAEKLAQDGISAHILDLRTVYPLDKEAIIEAASKTGKVLLVEDNKEGSIMSEVAAIIAENCLFD-----LDAPIARLAGPDVNPDKVEKAMRELAE............... 326
5 -16.000IDP00790 gene: pdhB; pyruvate dehydrogenase complex E1 component, beta subunit SACOL1103 [Staphylococcus aureus subsp. aureus COL]  ali follow..  11  11..............NDALKTELKNDQDVLIFGEDVGVNGGVFRVTEGLQKEFGEDRVFDTPLAESGIGGLAMGLAVEGFRPVMEVQFLGFVFFDAIAGQIARTRAPVTIRGPFGGGVHTPELHADNLEGILAQSPGLKVVIPSGPYDAKGLLISSIRSND----PVVYLEHMKLYRSFREEVPEEEYTIDIGKANVKK------------------------------------------------------------------EGNDISIITYGAMVQESMKAAEELEKDGYSVEVIDLRTVQPIDVDTIVASVEKTGRAVVVEAQRQAGVGAAVVAELSERAILS-----LEAPIGRVAAADTNKNDIIEKAKETLE............... 324
6 -15.800IDP02496 gene: pdhB; pyruvate dehydrogenase complex E1 component, beta subunit [Bacillus anthracis str. `Ames Ancestor`] GBAA4183 [Bacillus anthracis str. `Ames Ancestor`]  ali follow..  15  11..............TDALRVEMKNDPNVLVFGEDVGVNGGVFRATEGLQAEFGEDRVMDTPLAESGIGGLAVGLALEGFRPVPEIQFFGFVYMDSISGQLARMRAPVTVRSPFGGGVHTPELHADSLEGLVAQQPGLKVVIPSTPYDAKGLLISAIRDND----PVIYLEHMKLYRSFRQDVPEGEYTIDLGKADIKR------------------------------------------------------------------EGTDVSVIAYGAMVHAALKAAEELEKEGISLEVVDLRTVQPLDIETIIASVEKTGRVVVVEAQKQAGIAANVVAEINDRAILN-----LEAPVVRVAAADTNHKDIVEAVNKVMN............... 324
7 -15.200IDP02425 gene: acoB; TPP-dependent acetoin dehydrogenase E1 beta-subunit [Bacillus anthracis str. `Ames Ancestor`] GBAA2775 [Bacillus anthracis str. `Ames Ancestor`]  ali follow..  13  17.ISMRRDENVILIGEDGAQVDHLQDDEAWGGVLGVTKG-----LVQEFGRNRILDTPI----SEAGYMGAAMAAAATGLRPIAELMFNDFIGLDQVLNQGAKFRVPVTVRTMHGAGFSAAAQHSQSLYALFTSIPGIKVVVPSTPYDAKGLLLAAIEDDD----PVIFFEDKTLYNMKGEVPEIPLGKADIKR-----------------------------------------------------------------------EGSDVTIVAIGKQVHTALAAAEQLAKKGLEVEVIDPRSLSPLDEDTILSSVEKTNRLIVIEANPRCSIATDIAAIVADRGFDL-----LDAPIKRITAPHTTPEKVIETVSEMIGDQSLLH......... 343
8 -14.700IDP90935 C-terminal region of transketolase [Yersinia pestis CO92] YPO3313 [Yersinia pestis CO92]  ali follow..  14  1..MSNAEHLASVMVEQFIKAV--DNGVDLVPVVADSTSTAKIGPFITRFPDRVVNVGI----AEQAMVGMAVGLSMGGKIAVTCNAAPFLISRAQLKIDVCYNNSNVKLFGLNSGAGPLASTHHCIDDIAILRGFNIEIYAPADPQECRQIIDYALAHQGPVYIRLD-----ALPPLHDEHYRFAPGQIDVLQ-----------------------------------------------------------------------EGRDIALVAMGSTVHEAVSAAAILADNNISAAVVNVSSIRPCDTQQLFAILQQSQRVITIEEHNINGGVGSLVAEVEAGSGTPLVRLGIPDGGYAIAADRFDAAGIVARALRFCRGE............. 314
9 -14.400IDP02011 putative transketolase [Salmonella typhimurium LT2] STM2340 [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]  ali follow..  11  2IKLAPAGLKDDIEMRKVYAGFIAGQI-PIIALEADLMSSMAMDSVARDYPQHVINCGI----MEANVIGTAAGLALTGRKPFVHTFTAFASRRCQLFMALDYQRNNVKVIASDAGVTHNGGTHMSFEDMGIVRGLHSVVLEVTDAVMFADILRQLMDLDGFYWLRTI-----QARSIYAPGSTFTIGKGNVLR-----------------------------------------------------------------------EGDDITLIANGIMVAEALEAARQLEQEGVSAAVIDMFTLKPIDRMLVKNYAEKTRRIVTCENHSIHNGLGSAVAEVLVENCPVPMRRVGVKERYGQVGTQLTAEAIVEAAKSLL................ 317
10 -14.100IDP90880 gene: dxs; 1-deoxy-D-xylulose-5-phosphate synthase [Yersinia pestis CO92] YPO3177 [Yersinia pestis CO92]  ali follow..  12  326.............GEWLCETA--AKDSKLMAVTPAMREGSGMVRFSREYPQQYFDVAI----AEQHAVTFAAGLAIGGYKPVVAIYSTFLQRAYDQLIHDVAIQNLPVLFAIDRGGGADGQTHQGAFDLSFMRCINMVIMAPSDENECRQMLYTGYHHNGPAAVRYP---GNGTSAVLEPLEMLPIGKGVLRR-----------------------------------------------------------------------EGEKIAILCFGTLLAQAQLA-----AENLNATLVDMRFVKPLDEELVLEMAAKHQVLVTVEENAIMGGAG---SGVNELLMAKRRWVPVLNIGLPRSELGLDAAGIQRQIEAWLA............... 619
11 -13.200IDP02217 gene: dxs; 1-deoxy-D-xylulose-5-phosphate synthase [Francisella tularensis subsp. tularensis SCHU S4] FTT1018c [Francisella tularensis subsp. tularensis SCHU S4]  ali follow..  15  321.............GDWICQKA--AKDKRLVGITPAMKEGSDLIRFSQLYPHRYFDVAI----AEQHAVTFAGGLACQGLKPVVAIYSTFLQRAYDQVIHDIALQNLDVLYAVDRAGGADGATHDGSFDLAFMRCINHVIMTPSDENEAYHMLEFGYEYNGPAMVRYP---GAGIGAEITGSLDLELGKAKIVK-----------------------------------------------------------------------QGSKIAILNFGTLLPLAKQL-----AEKYHATVIDMRFVKPLDEIMLDKVSQTHEIILTLEENCIAGGAG---SAVNEYFVAKDLSNKIIVRNFGLQDK-LCVENISQELDKLI................ 615
12 -12.800IDP00089 gene: dxs; 1-deoxyxylulose-5-phosphate synthase; flavoprotein NT01ST0526 [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]  ali follow..  11  326.............GDWLCETA--AKDSKLMAITPAMREGSGMVEFSRKFPDRYFDVAI----AEQHAVTFAAGLAIGGYKPVVAIYSTFLQRAYDQVIHDVAIQKLPVMFAIDRAGGADGQTHQGAFDLSYLRCIDMVIMTPSDENECRQMLFTGYHYND---TAVRYPRGNAQGVALTPLEKLPIGKGLVKR-----------------------------------------------------------------------HGEKLAILNFGTLMPEAAKVA-----EALNATLVDMRFVKPLDDTLILEMAAQHDALVTLEENAIMGGAG---SGVNEVLMAHRKPVPVLNIGLPRAELGLDAAGIEAKIKAWLA............... 620
13 -10.100IDP91019 gene: poxB; pyruvate dehydrogenase [Yersinia pestis KIM 10] y2821 [Yersinia pestis KIM10+]  ali follow..  9  1.........MKQTVATLIAKTLEQAGVKRIWGVTGDSLNGLSDSLHR-----MGTIEWLGTRHEEVAAFAAGAAQLTGQLAVCGSCGPGNLHLINGLFDCHRNHVPVLAIAAHIPSSEIGSGYFQETHPQELRECSHYCELVSNPEQLPRVLEIAMRQAILNRGVSVIVLPGDVALQPAPEDAAVIWQTPKLPLVQPPMSELTLLADAKNITLMCGSGCADAHDEVVKLAERHALRGKEHIEWDNPYSVGMTGLIGFSSGYQAMLNAD-TLILLGTQFPYRAFYPTHANIIQIDINPGSLGAHCPVNMALVGDIKTTLTALLQLDAKSDRAFLDKALEHYRTTRQDLDALAT------ANDNQPIHPQYLAQQISHYATEDA............ 375
14 -9.920IDP02310 gene: tktA; transketolase [Francisella tularensis subsp. tularensis SCHU S4] FTT1369c [Francisella tularensis subsp. tularensis SCHU S4]  ali follow..  11  362..............QMVLEVLCKNMPEMFGGSADLTGSNNTNWSGSVWLNNTQEGANYLSY-REFGMAAIMNGLSLYGIKPYGGTFLVFSDYSRNAIRMSALMKQPVVHVMSHDSIGEDGPTHQPIEHVPSLRLINLSVWRPADTIE----TMIAWKEAVKSKDTPSVMV------------------------------------------------------------------TRQNLMPVVQTQHQVANIARGGYLVKDNPDAKLTIVATGSEVELAVKVANEFEKKGIKLNVASIPCVEVFATQAKKTVIKDDIPAVFVEMAQPDMWYKYMPKAEVKGIYSFGESAPAEDLFKRFG---FTVENISNIVAKYV................ 663
15 -9.460IDP02703 gene: tkt-1; transketolase [Bacillus anthracis str. `Ames Ancestor`] GBAA3432 [Bacillus anthracis str. `Ames Ancestor`]  ali follow..  16  370..............GEAINHYVKSIPSIFGGSADLSHSTMTDIKGEAVYAVESYAGRNIYF-REHAMGAAANGLALHGVKPFVSTFFVFNDYLRPSIRLAALQKLPVTYVFTHDSIGEDGPTHEPIEHLAALRAIGLTVIRPSDANE----TASAWAYALQQTEGPVVLV--------------------------------------------------------------LSRQNLPVFHETKANIENLSKGAYVLTQT--NENPDVILIATGSEVSLAASAKAKLEEDNVSVRIVAMPSWELFDRQSKEYKESVLPSSVTKRVSLEMGVSLGWERYVGQSIETFGASGTGAEVMNLFG---FTTENVVQITKNVLNS.............. 674
16 -9.290IDP90564 gene: tkt; transketolase [Campylobacter jejuni subsp. jejuni NCTC 11168] Cj1645 [Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819]  ali follow..  12  391...............................................................EHAMAAINNAFARYGFLPFSATFFIFSEYLKPAARIAALMKIKHFFIFTHDSIGEDGPTHQPIEQLSTFRAMNFLTFRPADGVE----NVKAWQIALNADIPSAFVL------SRQKLKALNEPVFGDVKN--------------------------------------------------------------GAYLLKESKEAKFTLLASGSEVWLCLESANELEKQGFACNVVSMPCFELFEKQDKAYQERLLGEVIGVEAAHSNELYKFCHKVYGIESFGESGKDKDVFERFG-----FSVSKLVNFILS.................. 631
17 -9.270IDP01792 gene: alsS; acetolactate synthase [Bacillus anthracis str. `Ames Ancestor`] GBAA0866 [Bacillus anthracis str. `Ames Ancestor`]  ali follow..  11  4.GVKANDVKTKTKGADLVVDCLIKQGVTHVFGIPGAKIDSVFDVLQER------GPELIVCRHEQNAAFMAAAGRLTGK-VCLVTSGPGTSNLATGLVTANAESDPVVALAGAVPRTDRLKRTHQSMDNAALEPITKYSVEVEHPDNVPEALSNAFRSATSTN-PGATLVSLPQDVMTAETTVESIGALSKPQLGIAPTHDITYVVEAKLPVILLG-------------MRASTNEVTKAVRALIADTELPVVETYQAAGAISRELEDHFFGRVGQPGDILLEEADLVISIGYDPIEYDPKFWNKLGDRTIIHL-ADIDHDYQPERELIGDIALTV-NSIAERLPKLVLSTKSEAVLERLSEGVTHPLQVIRTLRSLISDDT............ 391
18 -9.020IDP02454 gene: tkt-2; transketolase [Bacillus anthracis str. `Ames Ancestor`] GBAA3744 [Bacillus anthracis str. `Ames Ancestor`]  ali follow..  12  362..............GAVINAIAESVPSFFGGSADLAGSNKTYMNNEKDFTRDDYSGKNIWY-REFAMGAAMNGIALHGLKTYGGTFFVFSDYLRPAIRLAALMQLPVTYVFTHDSIGEDGPTHEPIEQLAALRAMNVSVIRPADGNE----SVAAWRLALESTNKPTALV--------------------------------------------------------------LTRQDLPTLEGAKDDTYEKVAKGAYVVSASKKETADVILLATGSEVSLAVEAQKALAVDGVDASVVSMPSMDRFEAQTAEYKESVLPKAVTKRFAIEMGATFGWHRYVGLGIDTFGASAPGEKIMEEYG---FTVENVVRKVKEML................ 666
FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Schwarzenbacher R, Godzik A, Jaroszewski L. The JCSG MR pipeline: optimized alignments, multiple models and parallel searches. Acta Crystallogr D Biol Crystallogr. 2008 Jan;64(Pt 1):133-40. Epub 2007 Dec 5.