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Query: TM0005 TM0005 281886 Purified-2001-01-30, from T.maritima

Results of FFAS03 search in H.sapiens
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MTVQQFIKKLVRLVELERNAEINAMLDEMKRLSGEEREKKGRAVLGLTGKFIGEELGYFLVRFGRRKKIDTEIGVGDLVLISKGNPLKSDYTGTVVEKGERFITVAVDRLPSWKLKNVRIDLFASDITFRRQIENLMTLSSEGKKALEFLLGKRKPEESFEEEFTPFDEGLNESQREAVSLALGSSDFFLIHGPFGTGKTRTLVEYIRQEVARGKKILVTAESNLAVDNLVERLWGKVSLVRIGHPSRVSSHLKESTLAHQIETSSEYEKVKKMKEELAKLIKKRDSFTKPSPQWRRGLSDKKILEYAEKNWSARGVSKEKIKEMAEWIKLNSQIQDIRDLIERKEEIIASRIVREAQVVLSTNSSAALEILSGIVFDVVVVDEASQATIPSILIPISKGKKFVLAGDHKQLPPTILSEDAKDLSRTLFEELITRYPEKSSLLDTQYRMNELLMEFPSEEFYDGKLKAAEKVRNITLFDLGVEIPNFGKFWDVVLSPKNVLVFIDTKNRSDRFERQRKDSPSRENPLEAQIVKEVVEKLLSMGVKEDWIGIITPYDDQVNLIRELIEAKVEVHSVDGFQGREKEVIIISFVRSNKNGEIGFLEDLRRLNVSLTRAKRKLIATGDSSTLSVHPTYRRFVEFVKKKGTYVIFLast
1 -97.700sp|Q92900|RENT1_HUMAN Regulator of nonsense transcripts 1 OS=Homo sapiens GN=UPF1 PE=1 SV=2  ali   33  3..................................................................................................................................................................................................................................................................................................................................................EKRYRALKRTAERELLMNADVICCTCVGAGDPRLAKMQFRSILIDESTQATEPECMVPVVLGKQLILVGDHCQLGPVVMCKKAAGLSQSLFERLVVL-GIRPIRLQVQYRMHPALSAFPSNIFYEGSLQNGVTAADRVKKGFDFQWPQPD----------KPMFFYVTQG----QEEIASSGTSYLNRTEAANVEKITTKLLKAGAKPDQIGIITPYEGQRSYLVQYMQQEVEIASVDAFQGREKDFIILSCVRANEHQGIGFLNDPRRLNVALTRARYGVIIVGNPKALSKQPLWNHLL............ 300
2 -94.800sp|P38935|SMBP2_HUMAN DNA-binding protein SMUBP-2 OS=Homo sapiens GN=IGHMBP2 PE=1 SV=3  ali   37  5............................................................................................................................................................................................................................................................................................................................VKNKKTQDKREKSNFRNEIKLLRKELKEREEAAMLESLTSANVVLATNTGASAKLLPESYFDVVVIDECAQALEASCWIPLLKARKCILAGDHKQLPPTTVSHKAAGLSLSLMERLAEEYGRVVRTLTVQYRMHQAIMRWASDTMYLGQLTAHSSVARHLLRDLPGV--------AATEETGVPLLLVDTAGCG-LFELEEEDEQSKGNPGEVRLVSLHIQALVDAGVPARDIAVVSPYNLQVDLLRQSLVHELEIKSVDGFQGREKEAVILSFVRSNRKGEVGFLAEDRRINVA....................................... 300
3 -93.200sp|Q6ZU11|YD002_HUMAN Uncharacterized protein FLJ44066 OS=Homo sapiens PE=1 SV=1  ali   32  1................................................................................................................................................................................................................................................................................................................................................................LLKQVRVVGVTCAACPFPCMNDLKFPVVVLDECSQITEPASLLPIARCEKLILVGDPKQLPPTIQGSDAAGLEQTLFDRLCLM-GHKPILLRTQYRCHPAISAIANDLFYKGALMNGVTEIERS----------------PLLEWLPTLCFYNVKG-----LEQIERDNSFHNVAEATFTLKLIQSLIASGIAGSMIGVITLYKSQMYKLCHLLSATVQVSTVDAFQGAEKEIIILSCVRTR---QVGFIDSEKRMNVALTRGKRHLLIVGNLACLRKNQLWGRVIQHCEGREDGLQ. 286
4 -90.700sp|P51530|DNA2L_HUMAN DNA2-like helicase OS=Homo sapiens GN=DNA2 PE=1 SV=3  ali   33  1...................................................................................................................................................................................................................................................................................................................................................................................FSRKIFDFCIVDEASQISQPICLGPLFFSRRFVLVGDHQQLPPLVLNREARGMSESLFKRLEQ-NKSAVVQLTVQYRMNSKIMSLSNKLTYEGKLECGSDKVANAVINLRHFKDVKLELEMGVFEPNNPVCFLNTDKVP---APEQVEKGGVSNVTEAKLIVFLTSIFVKAGCSPSDIGIIAPYRQQLKIINDLLARMVEVNTVDKYQGRDKSIVLVSFVRSNKDGTVGLLKDWRRLNVAITRAKHKLILLGCVPSLNCYPPLEKLLNHLNSEKLIIDL 292
5 -81.100sp|P38935|SMBP2_HUMAN DNA-binding protein SMUBP-2 OS=Homo sapiens GN=IGHMBP2 PE=1 SV=3  ali   35  1......................................................................................................................................ALIALKKYHSGIEVLFGRSAPSPASEIHPLTFFNTCLDTSQKEAVLFALSQKELAIIHGPPGTGKTTTVVEIILQAVKQGLKVLCCAPSNIAVDNLVERLALKQRILRLGHPARLLESIQQHSLDAVLARSDSAQIVADIRKDIDQVFVKN----------------------------------KKTQDKREKSNFRNEIKLLRKELKEREEAAMLESLTSANVVLATNTGASAKLLPESYFDVVVIDECAQALEASCWIPLLKARKCILAGDHKQLPPTTVSHKAAGLSLSLMERLAEEYGARVRTLTVQYRMHQAIMR................................................................................................................................................................................................... 300
6 -79.400sp|P42694|HELZ_HUMAN Probable helicase with zinc finger domain OS=Homo sapiens GN=HELZ PE=1 SV=2  ali   29  5..........................................................................................................................................................................................................................................................................................................................................................QMPQKEDILKHRVVVVTLNTSQYLCLEPGFFTHILLDEAAQAMECETIMPLALATRIVLAGDHMQLSPFVYSEFARNLHVSLLDRLYEHYPAERILLCENYRSHEAIINYTSELFYEGKLMASGKQPAH--------------------KDFYPLTFFTARG----EDVQEKNSTAFYNNAEVFEVVERVEELRRKKLDDGSIGVVTPYADQVFRIRAELRKDVNVERVLNVQGKQFRVLFLSTVRTRHDLDYGFLSNYKLLNTAITRAQSLVAVVGD.......................... 300
7 -78.800sp|Q7Z333|SETX_HUMAN Probable helicase senataxin OS=Homo sapiens GN=SETX PE=1 SV=4  ali   25  2......................................................................................................................................................................................................................................................................................................................RGGREIQRQELDENISKVSKERQELASKIKEVQGRPQKTQSIIILESHIICCTLSTSGGLLLESAPFSCVIVDEAGQSCEIETLTPLIHRNKLILVGDPKQLPPTVISMKAQGYDQSMMARFCRLLRLPILQLTVQYRMHPDICLFPSNYVYNRNLKTNRQTEAIRCSS---------------DWPFQPYLVFDVGDG-----SERRDNDSYINVQEIKLVMEIIKLIKDKDVSFRNIGIITHYKAQKTMIQKDLDKEAEVDTVDAFQGRQKDCVIVTCVRANSQGSIG.................................................. 300
8 -78.700sp|Q6ZU11|YD002_HUMAN Uncharacterized protein FLJ44066 OS=Homo sapiens PE=1 SV=1  ali   26  2........................................................................................................................................................................MASHESIEEVKELQTHTFPITIIHGVFGAGKSYLLAVVILFFVQRPWKLLISSSTNVAVDRVLLGLLSLENFIRVGSVRKIAKPILPYSLHAGSENESE--------------------------------------------------QLKELHALMKEDLTPTERVYVRKSIEQHKLGTNRTLLKQVRVVGVTCAACPFPCMNDLKFPVVVLDECSQITEPASLLPIARCEKLILVGDPKQLPPTIQGSDAAGLEQTLFDRLCLM-GHKPILLRTQYRCHPAISAIANDLFYKGALMNGVTEIERS----------------PLLEWLPTLCFYNVKGLEQIER........................................................................................................................................ 300
9 -77.600sp|Q92900|RENT1_HUMAN Regulator of nonsense transcripts 1 OS=Homo sapiens GN=UPF1 PE=1 SV=2  ali   29  29.......................................................................................................................................................................LPDLNHSQVYAVKTVL-QRPLSLIQGPPGTGKTVTSATIVYHLARQGNPVLVCAPSNIAVDQLTEKIHQGLKVVRLCAKSREAIDSPVSFLALHNQIRNMDS------------------------------------------------MPELQKLQQLKDETGELSSADEKRYRALKRTAERELLMNADVICCTCVGAGDPRLAKMQFRSILIDESTQATEPECMVPVVLGKQLILVGDHCQLGPVVMCKKAAGLSQSLFERLVVL-GIRPIRLQVQYRMHPALSAFPSNIFYEGSLQNGVTAADRVKKGFDFQW...................................................................................................................................................................... 300
10 -75.700sp|Q7Z333|SETX_HUMAN Probable helicase senataxin OS=Homo sapiens GN=SETX PE=1 SV=4  ali   22  2.....................................................................................................................................................................................SPSVAKICLIHGPPGTGKSKTIVGLLYRLLTEQNRVLVCAPSNAAVDELMKKIILDINLVRLGPEKSINSEVLKFSLDSQVNHRMKKELPSHVQAMHKRKEFLDYQLDELSRQRALCRGGREIQR------------QELDENISKVSKERQELASKIKEVQGRPQKTQSIIILESHIICCTLSTSGGLLLESAPFSCVIVDEAGQSCEIETLTPLIHRNKLILVGDPKQLPPTVISMKAQGYDQSMMARFC--------RLLEENVEHNMISRLP................................................................................................................................................................................................. 300
11 -74.600sp|O60306|AQR_HUMAN Intron-binding protein aquarius OS=Homo sapiens GN=AQR PE=1 SV=4  ali   22  3.....................................................................................................................................................................................................................................................................................................................................................................................GFKYDNILMEEAAQILEIETFIPLLLQKRWIMIGDHHQLPPVIKNMAFQNMEQSLFTRFVRV-GVPTVDLDAQGRARASLCNLYNWRYKN--LGNLPHVQLL------------PEFSTANAGLLYDFQLINVEDFQG-VGESEPNPYFYQNLGEAEYVVALFMYMCLLGYPADKISILTTYNGQKHLIRDIINRRNKVTTVDRFQGQQNDYILLSLVRTR---AVGHLRDVRRLVVAMSRARLGLYIFARVSLFQNCFELTPAFSQLTARPLHLHI 282
12 -73.300sp|Q9HCE1|MOV10_HUMAN Putative helicase MOV-10 OS=Homo sapiens GN=MOV10 PE=1 SV=2  ali   28  10..............................................................................................................................................................................................................................................................................................................................................................KKKLQEYRVLITTLITAGRLVFPIDHFTHIFIDEAGHCMEPESLVAIAGGGQLVLAGDPRQLGPVLRSPLTQGLGYSLLERLLTY-PQFITKLLRNYRSHPTILDIPNQLYYEGELQACADVVDRERFCRWAGLPRQG-----------PIIFHGVMG----KDEREGNSPSFFNPEEAATVTSYLKLLLAPRLSPRSVGVISPYRKQVEKIRYCITKDLKVGSVEEFQGQERSVILISTVRSS----QSFVQLDLDFNLGFLK.................................... 300
13 -72.500sp|Q9BYK8|PR285_HUMAN Peroxisomal proliferator-activated receptor A-interacting complex 285 kDa protein OS=Homo sapiens GN=PRIC285 PE=1 SV=6  ali   21  24...................................................................................................................................................................................................................................................................................................................................................TDDRQAFRPPTRAELARHRVVVTTTSQARELRVPVGFFSHILIDEAAQMLECEALTPLAYATRLVLAGDHMQVTPRLFSVARAAAEHTLLHRLFLCYRQSRLVFHENYRCTDAIVSFISRHFYVAKGNPIHARGKVPPHP-----------------RHYPLMFCHVAG----SPDRDMSMASWLNLAEIAQVVEKVQEAYNTGGREQRCICVVSHGAQVSALRQELRRQVSVGSFEILPGRQFRVVVLSTVHTCQSLAPEFFTDARVLNT........................................ 300
14 -71.500sp|Q7Z333|SETX_HUMAN Probable helicase senataxin OS=Homo sapiens GN=SETX PE=1 SV=4  ali   31  1.......................................................................................................................................................................................................................................................................................................................................................................................................................................................ILQLTVQYRMHPDICLFPSNYVYNRNLKTNRQTEAIR----------------SSDWPFQPYLVFDVGDG-----SERRDNDSYINVQEIKLVMEIIKLIKDKDVSFRNIGIITHYKAQKTMIQKDLDKEAEVDTVDAFQGRQKDCVIVTCVRANSQGSIGFLASLQRLNVTITRAKYSLFILGHLRTLMENQHWNQLIQDAQKRGAIIK. 199
15 -71.500sp|Q9BXT6|M10L1_HUMAN(removed signalp:1-18) Putative helicase Mov10l1 OS=Homo sapiens GN=MOV10L1 PE=1 SV=1  ali   33  1...........................................................................................................................................................................................................................................................................................................................................................................................................................LGPVIKSRLAMGLNVSFLERLMSRNPLLVTKLVKNYRSHEALLMLPSRLFYHRELEVCADPTVVTSLLGWEKLPKKGF----------PLIFHGVRG----SEAREGKSPSWFNPAEAVQVLRYCCLLAHSQVSASDIGVITPYRKQVEKIRILLRNDIKVGSVEEFQGQEYLVIIISTVRSNDRYFLGFLSNSKRFNVAITRPKALLIVLGNPHVLVRDPCFGALLEYSITNGVYMG. 255
16 -71.400sp|P51530|DNA2L_HUMAN DNA2-like helicase OS=Homo sapiens GN=DNA2 PE=1 SV=3  ali   28  15...............................................................................................................................................................AKDTVACILKGLNKPQRQAMKKVLLSKDYTLIVGMPGTGKTTTICTLVRILYACGFSVLLTSYTHSAVDNILLKLAKKIGFLRLGQIQKVHPAIQQFTEQEICRSK-----------------------------------------------------------------------------SIKSLALLEELYNSQLIVATTCMGINHPIFSRKIFDFCIVDEASQISQPICLGPLFFSRRFVLVGDHQQLPPLVLNREARGMSESLFKRLEQN-KSAVVQLTVQYRMNSKIMSLSNKLTYEGKLECGSDKVANAVINLR-----------HFKDVKLELEFYADYSDNPWLMGVFEPNNPFLNTDKV......................................................................................................................... 300
17 -71.200sp|Q9BYK8|PR285_HUMAN Peroxisomal proliferator-activated receptor A-interacting complex 285 kDa protein OS=Homo sapiens GN=PRIC285 PE=1 SV=6  ali   26  2...................................................................................................................................................................................................................................................................................................................................................................................................................................QNLGLDRSLFERYHED----AHMLDTQYRMHEGICAFPSVAFYKSKLKTWQGLRRPPSVLGHAG------------KESCPVIFGHVQGHERSVSTDEGNENSKANLEEVAEVVRITKQLTLGTVEPQDIAVLTPYNAQASEISKALRRGVAVSSITKSQGSEWRYVLVSTVRTCAKSDLGFVVDPNQVNVAVTRAQEGLCLIGDHLLLRCCPLWRSLLDFCEAQQTLVP. 235
18 -69.700sp|P38935|SMBP2_HUMAN DNA-binding protein SMUBP-2 OS=Homo sapiens GN=IGHMBP2 PE=1 SV=3  ali   36  1.......................................................................................................................................................................................................................................................................................................................................................................................................................................................................WASDTMYLGQLTAHSSVARHLLRDLPGVA--------ATEETGVPLLLVDTAGCG-LFELEEEDEQSKGNPGEVRLVSLHIQALVDAGVPARDIAVVSPYNLQVDLLRQSLVHELEIKSVDGFQGREKEAVILSFVRSNRKGEVGFLAEDRRINVAVTRARRHVAVICDSRTVNNHAFLKTLVEYFTQHGEVRT. 188
19 -66.800sp|Q9BYK8|PR285_HUMAN Peroxisomal proliferator-activated receptor A-interacting complex 285 kDa protein OS=Homo sapiens GN=PRIC285 PE=1 SV=6  ali   25  12......................................................................................................................................................................................................................RKLLRKSPREGRPNQSLRSI----------------------TLHHRIRQ------------------------------------------------APNPYSSEIKAFDTRLQRGELFSREDLVWYKKVLWEARKFELDRHEVILCTCSCAASASLKILDVRQILVDEAGMATEPETLIPLVQAEKVVLLGDHKQLRPVVKNERLQGLDRSLFERYHED----AHMLDTQYRMHEGICAFPSVAFYKSKLKTWQGLRRPPSVLGHAG------------KESCPVIFGHVQGHERSVSTDEGNENSKANLEEVAEVVRITKQLTLGTVEPQDIAVLTPYNAQASEISKALRRGVAVSSIT.......................................................................... 299
20 -66.300sp|Q9BYK8|PR285_HUMAN Peroxisomal proliferator-activated receptor A-interacting complex 285 kDa protein OS=Homo sapiens GN=PRIC285 PE=1 SV=6  ali   22  2..................................................................................................................................RKEEAVRGLEEASPLVTSIALGRPVPQERQTYNIPGGRHKLNPSQNVAVREAL-EKPFTVIQGPPGTGKTIVGLHIVFWFHKGGPCILYCGPSNKSVDVLAGLLLRELKPLRVYSEQAEASEFPVPRVGSRKLLRKSPREGRPNQSLRSITLHH------------------------RIRQAPNPYSSEIKAFDTRLQRGELFSREDLVWYKKVLWEARKFELDRHEVILCTCSCAASASLKILDVRQILVDEAGMATEPETLIPLVQFEKVVLLGDHKQLRPVVKNER...................................................................................................................................................................................................................................... 300
21 -59.900sp|Q6ZU11|YD002_HUMAN Uncharacterized protein FLJ44066 OS=Homo sapiens PE=1 SV=1  ali   33  1.......................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................DNSFHNVAEATFTLKLIQSLIASGIAGSMIGVITLYKSQMYKLCHLLSATVQVSTVDAFQGAEKEIIILSCVRTR---QVGFIDSEKRMNVALTRGKRHLLIVGNLACLRKNQLWGRVIQHCEGREDGLQ. 136
22 -59.400sp|Q92900|RENT1_HUMAN Regulator of nonsense transcripts 1 OS=Homo sapiens GN=UPF1 PE=1 SV=2  ali   39  3................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................PDKPMFFYVTQG----QEEIASSGTSYLNRTEAANVEKITTKLLKAGAKPDQIGIITPYEGQRSYLVQYMQQEVEIASVDAFQGREKDFIILSCVRANEHQGIGFLNDPRRLNVALTRARYGVIIVGNPKALSKQPLWNHLLNYYKEQKVLVE. 161
23 -58.000sp|P51530|DNA2L_HUMAN DNA2-like helicase OS=Homo sapiens GN=DNA2 PE=1 SV=3  ali   35  3..................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................PEQVEKGGVSNVTEAKLIVFLTSIFVKAGCSPSDIGIIAPYRQQLKIINDLLARMVEVNTVDKYQGRDKSIVLVSFVRSNKDGTVGLLKDWRRLNVAITRAKHKLILLGCVPSLNCYPPLEKLLNHLNSEKLIIDL 142
24 -57.800sp|Q9BXT6|M10L1_HUMAN(removed signalp:1-18) Putative helicase Mov10l1 OS=Homo sapiens GN=MOV10L1 PE=1 SV=1  ali   28  2................................................................................................................................................................................................GPPGTGKTVTIIEAVLQVHFADSRILVCAPSNSAADLVCLRLHES-TMVRVNATCRFEEIVIDAVKPYCRDGED------------------------------------------------------------------------------------IWKASRFRIIITTCSSSGQIGVRVGHFTHVFVDEAGQASEPECLIPLGISGQIVLAGDPMQLGPVIKSRLAMGLNVSFLERLMSR-PLLVTKLVKNYRSHEALLMLPSRLFYHRELEVCADPTVVTSLLGWEKLPKKG-----------PLIFHGVRG----SEAREGKSPSWFNPAEAVQVLRYCCLLAHSQVSASDIGVITP................................................................................................ 300
25 -57.200sp|Q9BYK8|PR285_HUMAN Peroxisomal proliferator-activated receptor A-interacting complex 285 kDa protein OS=Homo sapiens GN=PRIC285 PE=1 SV=6  ali   20  1......................................................................................................................................................................................................................................................................................................................................................................................................................................................................SFISRHFYVAKGNPIHARGKVPPHP-----------------RHYPLMFCHVAG----SPDRDMSMASWLNLAEIAQVVEKVQEAYNTGGREQRCICVVSHGAQVSALRQELRRQVSVGSFEILPGRQFRVVVLSTVHTCQSLAPEFFTDARVLNTVLTRAQSQLVVVGDAVALCSGKLWESFIRECVERHSVCP. 193
26 -56.000sp|P38935|SMBP2_HUMAN DNA-binding protein SMUBP-2 OS=Homo sapiens GN=IGHMBP2 PE=1 SV=3  ali   32  5.AVESFVTKQLDLLELERDAEVEERRSWQENISLKELQSRGVCLLKLQVSSQRTGLGRLLVTFEPRRLPSNSFTSGDIVGLYDAANEGSQATGILTRVTQKSVTVAFDESHDDRENSYRLLKLANDVTYRRLKKALIALKKYHSGIEVLFGRSAPSPASEIHPLTFFNTCLDTSQKEAVLFALSQKELAIIHGPPGTGKTTTVVEIILQAVKQGLKVLCCAPSNIAVDNLVERLALKQRILRLGHPARLLESIQQHSLDAVLARSDSAQIVADIRKDI.................................................................................................................................................................................................................................................................................................................................................................................... 300
27 -55.700sp|P42694|HELZ_HUMAN Probable helicase with zinc finger domain OS=Homo sapiens GN=HELZ PE=1 SV=2  ali   24  2..................................................................................................................................EMHYALDRIKDNGVLFPDISMTPTIPWSPNRQWDEQLDPRLNAKQKEAVLAITTPLAIVLIIGPYGTGKTFTLAQAVKHILQQQERILICTHSNSAADLYIKDYLHQARPLRVYFRNRWVKTVHPVVHQY----------------------------------------------------------------------------CLISSAHSTFQMPQKEDILKHRVVVVTLNTSQQLDLEPGFFTHILLDEAAQAMECETIMPLALATRIVLAGDHMQLSPFVYSEFARNLHVSLLDRLYEHYPAERILLCENYRSHEAIINYTSELFYEGKLMASGKQPAHK.............................................................................................................................................................................. 295
28 -54.000sp|Q9HCE1|MOV10_HUMAN Putative helicase MOV-10 OS=Homo sapiens GN=MOV10 PE=1 SV=2  ali   36  25...................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................PIIFHGVMG----KDEREGNSPSFFNPEEAATVTSYLKLLLAPSLSPRSVGVISPYRKQVEKIRYCITKDLKVGSVEEFQGQERSVILISTVRSSQSFNLGFLKNPKRFNVAVTRAKALLIIVGNPLLLGHDPDWKVFLEFCKENGGYTG. 196
29 -52.900sp|Q9P2E3|ZNFX1_HUMAN NFX1-type zinc finger-containing protein 1 OS=Homo sapiens GN=ZNFX1 PE=1 SV=2  ali   28  1.......................................................................................................................................................................................................................................................................................................................................................................................................................................LEVSLFERLVKV-NIPFVRLNYQHRMCPEIARLLTPHIYQ-DLENHPSVLKY----------------EKIKGVSSNLFFVE----HNFPEQEIQEGKSHQNQHEAHFVVELCKYFLCQEYLPSQITILTTYTGQLFCLRKLMPAKVRVHVVDKYQGEENDIILLSLVRSNQEGKVGFLQISNRICVALSRAKKGMYCIGNMQMLAKVPLWSKIIHTLRENNQI... 206
30 -50.800sp|Q9BYK8|PR285_HUMAN Peroxisomal proliferator-activated receptor A-interacting complex 285 kDa protein OS=Homo sapiens GN=PRIC285 PE=1 SV=6  ali   22  13.................................................................................................................ARLVLEVQFQIDPMTFRLWHQAVDTLPEEQ-----LVVPDLPTCALPRPWSVPPLRRGNRKQELAVALIAGWGPGDLIYGPFGTGKTYTLAMASLEVIRRPEKVLICTHTNSAADIYIREYFHEATPLRVMYTDRPLSQTDPVTLQYCCLTDDRQAFRPPTRAE----------------------------------------------------------------------------LARHRVVVTTTSQARELRVPVGFFSHILIDEAAQMLECEALTPLAYATRLVLAGDHMQVTPRLFSVARAAAEHTLLHRLFLCYQQERLVFHENYRCTDAIV.................................................................................................................................................................................................... 300
31 -50.700sp|P42694|HELZ_HUMAN Probable helicase with zinc finger domain OS=Homo sapiens GN=HELZ PE=1 SV=2  ali   28  1.....................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................TFFTARG----EDVQEKNSTAFYNNAEVFEVVERVEELRRKWLDDGSIGVVTPYADQVFRIRAELRKDVNVERVLNVQGKQFRVLFLSTVRTRHDLDYGFLSNYKLLNTAITRAQSLVAVVGDPIALCSRKFWERFIALCHENSSLHGI 180
32 -50.500sp|Q9HCE1|MOV10_HUMAN Putative helicase MOV-10 OS=Homo sapiens GN=MOV10 PE=1 SV=2  ali   24  2..............................................................................................................................QPLRVQHRALELTGRWLLWPMLFPRDVPLLPSDVKLKLYDRSLESNPEQLQAMRHIVTGTT-YIIFGPPGTGKTVTLVEAIKQVVKHKAHILACAPSNSGADLLCQRLRVPSSIYRLLAPSRDIRMVPEDIKPCCNWDAKKGEYVFPAKKK----------------------------------------------------------------------------LQEYRVLITTLITAGR--FPIDHFTHIFIDEAGHCMEPESLVAIAPGGQLVLAGDPRQLGPVLRSPLTQGLGYSLLERLLTYNPQFITKLLRNYRSHPTILDIPNQLYYEGE......................................................................................................................................................................................... 300
33 -46.700sp|Q9P2E3|ZNFX1_HUMAN NFX1-type zinc finger-containing protein 1 OS=Homo sapiens GN=ZNFX1 PE=1 SV=2  ali   25  38............................................................................................................................................................................................................................................................................................................................LQLYQADTRRKILSYERQYRTSAERMAELRLQEDLHILKDAQVVGMTTTGAARQILQKVEPRIVIVEEAAEVLEAHTIATLSKAQHLILIGDHQQLRPSANVYDLANLEVSLFERLVKV-NIPFVRLNYQHRMCPEIARLLTPHIYQ-DLENHPSVLKY----------------EKIKGVSSNLFFVE----HNFPEQEIQEGKSHQNQHEAHFVVELCKYFLCQEYLPSQITILTTYTGQLFCLRKLMPAKVRVHVVDKYQGEENDIILLSLV........................................................... 300
34 -46.400sp|P51530|DNA2L_HUMAN DNA2-like helicase OS=Homo sapiens GN=DNA2 PE=1 SV=3  ali   22  2................SQSKDNKKNHQNIWLMPASEMEKSGSCIGNLIRMEHVKIDGQYLHNFQCKAIPVTNLMAGDRVIVSGEERSLALSRGYVKEINMTTVTCLLDRNLSVESTLFRLDQEEKNCDIDTPLGNLSKLMENTKKLRDLIIDFREPQHDAKDTVACILKGLNKPQRQAMKKVLLSKDYTLIVGMPGTGKTTTICTLVRILYACGFSVLLTSYTHSAVDNILLKLAKKIGFLRLGQIQKVHPAIQQFTEQEICRSKSIKSLAL-----------------------------------------------------------------------------LEELYNSQLIVATTCMGINHPI....................................................................................................................................................................................................................................................................................... 300
35 -45.300sp|O60306|AQR_HUMAN Intron-binding protein aquarius OS=Homo sapiens GN=AQR PE=1 SV=4  ali   28  3...............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................EAEYVVALFMYMCLLGYPADKISILTTYNGQKHLIRDIINRRNKVTTVDRFQGQQNDYILLSLVRTR---AVGHLRDVRRLVVAMSRARLGLYIFARVSLFQNCFELTPAFSQLTARPLHLHI 132
36 -41.900sp|Q92900|RENT1_HUMAN Regulator of nonsense transcripts 1 OS=Homo sapiens GN=UPF1 PE=1 SV=2  ali   21  1....QYQNIFGPLVKLEADYDKKL--------------KESQTQDNITVRWDLGLNKKRIAYFTLPKLRDMRLMQGDEICLRYKGDLAPLWKGIGPDNYGDEIAIELRSSPVEVTHNFQVDFVWKSTSFDRMQSALKTFAVDETSVSGYIYHKIIKCQLPKRFTAQGLPDLNHSQVYAVKTVL-QRPLSLIQGPPGTGKTVTSATIVYHLARQGNPVLVCAPSNIAVDQLTEKIHQGLKVVRLCAKSRIDSPVSFLALHNQIRNMDSMPELQKLQQLKDETGELSS............................................................................................................................................................................................................................................................................................................................................................................ 300
37 -40.800sp|P42694|HELZ_HUMAN Probable helicase with zinc finger domain OS=Homo sapiens GN=HELZ PE=1 SV=2  ali   17  1LTKSNYQSRLHDLLYIEEIAQYKEISKFNLKVQLQILASFMLTGVSGGAKYAQNGQLFGRFKLTETLSEDTLMTKVNAVYLLTQGTKEKVYEATIEEKTKEYIFLRLSRERPDCDTQVELQFQLNRLPLCEMHYALDRIKDNGVLFPDISMTPTIPWSPNRQWDEQLDPRLNAKQKEAVLAITTPLA-VLIIGPYGTGKTFTLAQAVKHILQQETRILICTHSNSAADLYIKDYLHQARPLRVYFRNRWVKTVHPVVHQ....................................................................................................................................................................................................................................................................................................................................................................................................... 293
38 -39.400sp|Q9BXT6|M10L1_HUMAN(removed signalp:1-18) Putative helicase Mov10l1 OS=Homo sapiens GN=MOV10L1 PE=1 SV=1  ali   19  29.............................................................................LEHVIHLGVKVLFPEEIILQSPQVTGNWNHAQSSGQSTSKKNRKTMTDQAEHGTEERRVGDKDLPVLAPFTAEMSDDEIQTPKARKMEFFNPVLNENQKLAVKRILSGDCRPILFGPPGTGKTVTIIEAVLQVHFADSRILVCAPSNSAADLVCLRLHES-TMVRVNATCRFEEIVIDAVKPYCRDGEDIWK------------------------------------------------------------------------------------ASRFRIIITTCSSSGQIGVRVGHFTHVFVDEAGQASEPECLIPLGISGQIVLAGDPMQ............................................................................................................................................................................................................................................... 300
39 -39.400sp|Q7Z333|SETX_HUMAN Probable helicase senataxin OS=Homo sapiens GN=SETX PE=1 SV=4  ali   22  1....................................................................KQLYPKENDLVFLAPERINHEYHSGYVHKFRRTSVMRNGENFPANLNELVNCIVISSLVTTQRKLKAMSLLGSRNQLARAVLFCTKDLLTTTSERIIAYLRDFNEDQKKAIETAYAVAKICLIHGPPGTGKSKTIVGLLYRLLTENQRVLVCAPSNAAVDELMKKIILDINLVRLGPEKSINSEVLKFSLDSQVNHR--------MKKELPSHVQAMHKRKEFLDYQLDELSRQRAL......................................................................................................................................................................................................................................................................................................................................................... 300
40 -38.900sp|O60306|AQR_HUMAN Intron-binding protein aquarius OS=Homo sapiens GN=AQR PE=1 SV=4  ali   17  2.....................................................................................................................................................................................................................................LARRIELLEEVKRLQKSLGVPGDASYTCETAGFFLYQVMSRWEEYISKVKNKGSTLPDVTEVSTFFPFHEYFANAPQPIFKGRSYEEDMEIAEGCFRHIKKIFTQLEEFRELLRSGLDRSKYLLVKEAKIIAMTCTHAALKRHDGFKYDNILMEEAAQILEIETFIPLLLQKRWIMIGDHHQLPPVIKNMAFQNMEQSLFTRFVRV-GVPTVDLDAQGRARASLCNLYNWRYKN--LGNLPHVQLL------------PEFSTANAGLLYDFQLINV-------EDFQGVGESEPNPYFYQ........................................................................................................................ 299
41 -37.000sp|Q9HCE1|MOV10_HUMAN Putative helicase MOV-10 OS=Homo sapiens GN=MOV10 PE=1 SV=2  ali   18  31LKWRNYEVKLRLLLHLEELQMEHDIRH--------------YDLESVPMTWDPVDQNPRLLTLEVPGVTESRVLRGDHLFAETHQEDPITYKGFVHKVELDRVKLSFSMSRFVDGLTFKVNFTFNRQPLRVQHRALELTGRWLLWPMLFPRDVPLLPSDVKLKLYDRSLESNPEQLQAMRHIVTGTT-YIIFGPPGTGKTVTLVEAIKQVVKHKAHILACAPSNSGADLLCQRLRVPSSIYRLLAPSRDIRMVPEDIKP....................................................................................................................................................................................................................................................................................................................................................................................................... 294
42 -34.600sp|Q9BYK8|PR285_HUMAN Peroxisomal proliferator-activated receptor A-interacting complex 285 kDa protein OS=Homo sapiens GN=PRIC285 PE=1 SV=6  ali   18  37ISPTNYRQRMHQFLYEEEAAQQQLVAKLTLRGQVFLKTALQTPALNMLFAPP----GALYAEVPVPSSLMPDTDQGFLLGRAVSAPDNTVFEVRLERRASSEQALWLLGLQPEARLVLEVQFQIDPMTFRLWHQAVDTLPEEQ-----LVVPDLPTCALPRPWSVPPLRRGNRKQELAVALIAGWGPGDLIYGPFGTGKTYTLAMASLEVIRRPEKVLICTHTNSAADIYIREYFH--SHVSGGHPEA.................................................................................................................................................................................................................................................................................................................................................................................................................. 298
43 -33.900sp|Q9BYK8|PR285_HUMAN Peroxisomal proliferator-activated receptor A-interacting complex 285 kDa protein OS=Homo sapiens GN=PRIC285 PE=1 SV=6  ali   17  25.ASRTPQGQLQGAFRLEAAFLEENCADINFSCCYLCIRLEGLPAPTASPRPGPSSLG---PGLNVDPGTYTWVAHGQTQDWDQERRADRQEAPRVHLFVHHMGMEKVPEEVLRPGTLFTVELLPKQLPDLRKEEAVRGLEEASPLVTSIALGPSRFLERQTYNIPGGRHKLNPSQNVAVREAL-EKPFTVIQGPPGTGKTIVGLHIVFWFHKSNQCILYCGPSNKSVDVLAGLLLRELKPLRVYSEQA.................................................................................................................................................................................................................................................................................................................................................................................................................. 299
44 -33.600sp|Q6ZU11|YD002_HUMAN Uncharacterized protein FLJ44066 OS=Homo sapiens PE=1 SV=1  ali   24  153.........................................................................................................................................................................ASHESIEEVKELQTHTFPITIIHGVFGAGKSYLLAVVILFFVQRPWKLLISSSTNVAVDRVLLGLLS-ENFIRVGSVRKIAKPILPYSLHAGSENESEQLKELHALMKEDLTPTERVYVRKSIEQHKLGTNRT............................................................................................................................................................................................................................................................................................................................................................ 300
45 -29.500sp|O60306|AQR_HUMAN Intron-binding protein aquarius OS=Homo sapiens GN=AQR PE=1 SV=4  ali   19  51.........................................................................................................................................................................QFTHTQIEAIRAGM-QPGLTMVVGPPGTGKTDVAVQIISNIYHNEQRTLIVTHSNQALNQLFEKIMAERHLLRLGHGEE--ELETEKDFSRYGRVNYVLARRIELLEEVKRLQKSLGVPGDASYTCETAGYFFLYQVMSRWEEYISKVKNKGSTLFRHIKKIFTQLEEFRELLRSGLDRSKYLLVKEAKIIAMTCTHAA.......................................................................................................................................................................................................................................................................................... 293
46 -27.300sp|Q7Z333|SETX_HUMAN Probable helicase senataxin OS=Homo sapiens GN=SETX PE=1 SV=4  ali   34  1........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................FLASLQRLNVTITRAKYSLFILGHLRTLMENQHWNQLIQDAQKRGAIIK. 49
47 -26.400sp|O60306|AQR_HUMAN Intron-binding protein aquarius OS=Homo sapiens GN=AQR PE=1 SV=4  ali   24  201.........................................................................................................................................................................QFTHTQIEAIRAGM-QPGLTMVVGPPGTGKTDVAVQIISNIYHNEQRTLIVTHSNQALNQLFEKIMAERHLLRLGHGEEELETEKDFSRYGRVN................................................................................................................................................................................................................................................................................................................................................................................................... 299
48 -23.300sp|Q68D06|SLN13_HUMAN Schlafen family member 13 OS=Homo sapiens GN=SLFN13 PE=2 SV=1  ali   12  1..................................................................................................................................................................................................PGSGKTIMAMKIMEKIRNEAHRILYVCENQPLRNFISDRNICRAETRETFLREKFE-----------------------------------------------------------------------------------------------------------------------------HIQHIVIDEAQRKAKTITQREKDCPGVLWIFLDYFQ---------------TSHLG---SAQYPREELTRVVRNADEIAEYIQQEMQLIIENPPINIPHGYLAILSEAKWVPG------------------------VPGNTKIIKNFTLEQIVTYVADTCRCFFERGYSPKDVAVLVSTVTEVEQYQSKLGVHIVLDSVRRFSGLERSIVFGIHPRTADPA-----ILPNILICLASRAKQHLYIF............................ 296
49 -23.300sp|P0C7P3|SLN14_HUMAN Schlafen family member 14 OS=Homo sapiens GN=SLFN14 PE=2 SV=2  ali   14  41............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................TEQIANYVARKCHSLFQCGYLPKDIAILCRRGEDRGRYRLALGSHIVLDSIQQFSGLERTVVFGLSPECDQS-------EEFHKLCFASRAIKHLYLLYEKRA....................... 160
50 -22.700sp|Q7Z7L1|SLN11_HUMAN Schlafen family member 11 OS=Homo sapiens GN=SLFN11 PE=1 SV=2  ali   12  1..................................................................................................................................................................................................PGSGKTIMAMKIMEKIRNEAHRILYVCENQPLRNFISDRNICRAETRKTFLRENFE-----------------------------------------------------------------------------------------------------------------------------HIQHIVIDEA-QNFRTEDGDWYGKAKSITIFLDYFQ---------------TSHLDCSGLPP-PREELTRIVRNADPIAKYLQKEMQVIRSNPSFNIPTGCLEVFPEAEWSQG------------------------VQGTLRIKKYLTVEQIMTCVADTCRRFFDRGYSPKDVAVLVSTAKEVEHYKYELLKAIVLDSVRRFSGLERSIVFGIHPRTADPA-----ILPNVLICLASRAKQHLYIFPWGG........................ 300
51 -22.600sp|Q9P2E3|ZNFX1_HUMAN NFX1-type zinc finger-containing protein 1 OS=Homo sapiens GN=ZNFX1 PE=1 SV=2  ali   20  1.............................................................................................................................................................................SQMEALQFAL-TRELAIIQGPPGTGKTYVGLKIVQALLTNESVILVVCYTNHALDQFLEGIYN--SIVRVGGRSN-SEILKQFTLRELRNKREFRRAYMSIMTQMKESEQELHEGAKTLECTMRGVLREQYLQKYISPQHWESLDEEEEGEEESSLIEIAEEADLIQADRVIEEEEVVRPQRRKKEESGADQELAKMLMRLDHCGTGTAAGQEQATGEWQT................................................................................................................................................................................................................................................................ 289
52 -22.300sp|Q08AF3|SLFN5_HUMAN Schlafen family member 5 OS=Homo sapiens GN=SLFN5 PE=1 SV=1  ali   9  12.........................................................................................................................................................................................................................................................................................................................................................NQPLKKLVSFSKKNICQPVTRKTFMKNNFEHIQHIIIDDAQGKAKFITQTARDGPGVLWIFLDYFQ---------------TYHLSCSGSDQYPREEINRVVRNAGPIANYLQQVMQEARQNPPPNLPPGSLVMLYEPKWAQG------------------------VPGNLEIIEDLNLEEILIYVANKCRFLLRNGYSPKDIAVLFTKASEVEKYKDRLLTAIVLDSVCRFSGLERNIVFGINPGVAPPA-----GAYNLLLCLASRAKRHLYILKAS......................... 290
53 -21.900sp|Q9P2E3|ZNFX1_HUMAN NFX1-type zinc finger-containing protein 1 OS=Homo sapiens GN=ZNFX1 PE=1 SV=2  ali   20  1...........................................................................GSLVCMSK-DNFETFLFATVSNLCRGIVQLCFNEQSQQSDSFLMVETTAYFEAYRHVLEGLQEVQEEDVPFQRNIVECNSHVKEPRYLLMG-ALKLDDSQMEALQFAL-TRELAIIQGPPGTGKTYVGLKIVQALLTNESVILVVCYTNHALDQFLEGIYN--SIVRVGGRSN-SEILKQFTLRELRNKREFRRAYMSIMTQMKESEQELHEGAKTLECTMRGVLREQYLQ........................................................................................................................................................................................................................................................................................................................................................ 300
54 -21.000sp|Q9P2E3|ZNFX1_HUMAN NFX1-type zinc finger-containing protein 1 OS=Homo sapiens GN=ZNFX1 PE=1 SV=2  ali   29  1...............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................RSNQEGKVGFLQISNRICVALSRAKKGMYCIGNMQMLAKVPLWSKIIHTLRENN..... 54
55 -20.100sp|Q8NFZ0|FBX18_HUMAN F-box only protein 18 OS=Homo sapiens GN=FBXO18 PE=1 SV=2  ali   13  3......................................................................................................................................................................................MEPLQVVKIMAFAGTGKTSTLVKYAEKW--SQSRFLYVTFNKSIAKQAERVFPSNVIC-------KTFHSMAYGHIGRKYQSKKKLNLFKLTPFMVNSVLAEGKGGFIRAKLVCKTLENFFASADEELTIDHVPIWCKNSQGQRVMVEQSEKLNGVLEASRLWDNMRKLGECTEEAHQMTHDGYLKLWQLSK-SFDAIFVDEAQDCTPAIMNIVLSQPCGKIFVGDPHQ---QIYTFRGA------VNALFTVPHTHVFYLTQSFRFGVEIAYVGATIL............................................................................................................................................................................................. 266
56 -19.700sp|Q9P2E3|ZNFX1_HUMAN NFX1-type zinc finger-containing protein 1 OS=Homo sapiens GN=ZNFX1 PE=1 SV=2  ali   23  188............................................................................................................................................................................................................................................................................................................................LQLYQADTRRKILSYERQYRTSAERMAELRLQEDLHILKDAQVVGMTTTGAAKQILQKVEPRIVIVEEAAEVLEAHTIATLSKAQHLILIGDHQQLRPSANVYD----------------------LAKNFN.......................................................................................................................................................................................................... 300
57 -19.600sp|Q9BXT6|M10L1_HUMAN(removed signalp:1-18) Putative helicase Mov10l1 OS=Homo sapiens GN=MOV10L1 PE=1 SV=1  ali   11  57LNMSNYKEKFSTLLWLEEIYAEMELKE-----------------YNMSGIILRRNGDLLVLEVPGLAEGRPSLYAGDKLILKTYNGHAIEYISYVTEIHEEDVTLKINPEQAYNFEPMDVEFTYNRTTSRRCHFALEHVIHLGVKVL-FPEEIILQSPQVTGNWNHAQDTKSSGQSTSKKNRKTMTD-GTEERRVGDKDLPVLAPFTAEMSDQTPKARKMEFFNPVLNENQKLAVKRI............................................................................................................................................................................................................................................................................................................................................................................................................................ 288
58 -19.500sp|P0C7P3|SLN14_HUMAN Schlafen family member 14 OS=Homo sapiens GN=SLFN14 PE=2 SV=2  ali   11  4.....................................................................................................................................................................................................................................................................................................................................................IKIMEKIKDLFHCKPKEILYVCESDSLKDFVTQQKIKHIVMDET-ENFCSKYGNWYMKAKNITLFLDPFQ---------------IHHAD---SAQFPRKTITSGIHCALEIAKVMKEEMKRIKENPPSNMSPDTLALFSETAYEEATCAQALPGVCETKTNLT-------------------TEQIANYVARKCHSLFQCGYLPKDIAILCRRGEDRGRYRLALLKAIVLDSIQQFSGLERTVVFGLSPECDQS-------EEFHKLCFASRAIK................................. 300
59 -18.900sp|Q7Z7L1|SLN11_HUMAN Schlafen family member 11 OS=Homo sapiens GN=SLFN11 PE=1 SV=2  ali   13  36.............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................EQIMTCVADTCRRFFDRGYSPKDVAVLVSTAKEVEHYKYELGDHIVLDSVRRFSGLERSIVFGIHPRTADPAI-----LPNVLICLASRAKQHLYIFPWGG........................ 150
60 -18.000sp|Q8NG08|HELB_HUMAN DNA helicase B OS=Homo sapiens GN=HELB PE=1 SV=2  ali   13  3.........................................................................................................................................................................PLDRDQVAALEMICSNP-VTVISGKGGCGKTTIVSRLFKHIEQKAIEVLLTAPTGKAAGLLRQK-----------------TGLHAYTLCQVNYSFYSWTQTMMTTNK----------------------------------------------------------------------------------------------WKFSSVRVLVVDEGSL-VSVGIFKSVLNLSKLIILGDIRQLPSI-----------NLLKDLFETLKSRNCAIELKNHRAES----------QLIVDNATRISRRQFPKFDAELNISDNPTLPISIQDKTFIFVRL--------PEEDASSQSSKTNHHSCLYSAVKTLLQEN-NAKTSQFIAFRRQD............................................................................................ 298
61 -16.300sp|O15050|TRNK1_HUMAN TPR and ankyrin repeat-containing protein 1 OS=Homo sapiens GN=TRANK1 PE=2 SV=4  ali   14  5........................................................................................................................................................................................................................................................................................................................................................QQIRSQKGYFDEEDVLYNISRRLSKLRVLPWSIHELYGDEIQDFTQAELAL-INDPNSMFLTGDTAQ---SIMKGVAFRFSRSLFKQCAVRKPKKIHQLYQNYRSHSGILNLASGVVDLLQFYFPESFDRLPRD-------------SGLFDGPKPTVL------------------ESCSVSDLAILLRGNKRKTQPIEFGAHQVILVANETAKEKIPEELGLAL-VLTIYEAKGLEDDVLLYNFFTDSEAYK--LNGELKQLYTAITRA................................... 300
62 -13.900sp|Q7Z333|SETX_HUMAN Probable helicase senataxin OS=Homo sapiens GN=SETX PE=1 SV=4  ali   11  89.NYGDYFNVFFPLMVLNTFETVAQEWLNSPNRENFYQLQ-----VRKFPADYIKYWEFAVYLEECELAKQLYPKENDLVFLAPERINEEKHSGYVHKFRRTSVM-TQENFPANLNELVNCIVISSLVTTQRKLKAMSLLGSRNQLARAVLFCTKDLLTTTSERIIAYLRDFNEDQKKAIETAY-----AMVK.......................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 300
63 -13.400sp|Q8NFZ0|FBX18_HUMAN F-box only protein 18 OS=Homo sapiens GN=FBXO18 PE=1 SV=2  ali   11  1.............................................................................................................................................................................................................................................................................................................................................EASRLWDNMRKLGECTEEAHQMTHDGYLKLWQLSKPSL----SFDAIFVDEAQDCTPAIMNIVLSQPCGKIFVGDPHQ---QIYTFRGA------VNALFTVPHTHVFYLTQSFRFGVEIAYVGATILDVCKRVRKKTLVGGNHQSGIRGDAKGQVALLSRTNANVFDEAVRVTEGEFPSRIHLIGGIKSFGLDRIIDIWILLQTAAEDKELEAKIAVVEKYNIRIPELVQRIFAEYILGTVHKAKGLEFDTVHVL............................................................. 286
64 -13.200sp|Q8NG08|HELB_HUMAN DNA helicase B OS=Homo sapiens GN=HELB PE=1 SV=2  ali   19  153.........................................................................................................................................................................PLDRDQVAALEMICSNP-VTVISGKGGCGKTTIVSRLFKHIEQLEEEVLLTAPTGKAAGLLRQKTGLHAYTLC........................................................................................................................................................................................................................................................................................................................................................................................................................ 259
65 -11.900sp|Q68D06|SLN13_HUMAN Schlafen family member 13 OS=Homo sapiens GN=SLFN13 PE=2 SV=1  ali   15  127..........................................................................................................................................................................LTAQQYEIFSRSLRKNRELFVHGLPGSGKTIMAMKIMEKIRNEAHRILYVCENQPLRNFISDRNICRAETRETFLREKFE-----------------------------------------------------------------------------------------------------------------------------HIQHIVIDEAQNFRT-RKAKTITQPGVLWIFLDYFQ-----SHLGHSGLPPLSAQ-------YPREELTRVVRNADEIAEYIQQEM............................................................................................................................................................................................. 295
66 -11.600sp|Q8NFZ0|FBX18_HUMAN F-box only protein 18 OS=Homo sapiens GN=FBXO18 PE=1 SV=2  ali   20  140.........................................................................................................................................................................QLTHEQQLILNHKMEPLQVVKIMAFAGTGKTSTLVKYAEKW--SQSRFLYVTFNKSIAKQAERVFPSNVIC.......................................................................................................................................................................................................................................................................................................................................................................................................................... 208
67 -11.500sp|Q8NG08|HELB_HUMAN DNA helicase B OS=Homo sapiens GN=HELB PE=1 SV=2  ali   13  73.................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................KRDFESNVRLCN-GEIFFITNDVTD--VTFGKRRSLTINNMAGLEVTVDFKKLMKYCRIKTIHTFQGSEEQTVVYVVGKAG-------RQHWQHVYTAVTRGRCRVYVIAEESQLRN.................... 184
68 -11.400sp|Q7Z7L1|SLN11_HUMAN Schlafen family member 11 OS=Homo sapiens GN=SLFN11 PE=1 SV=2  ali   15  127..........................................................................................................................................................................LTAQQYEIFSRSLRKNRELFVHGLPGSGKTIMAMKIMEKIRNEAHRILYVCENQPLRNFISDRNICRAETRKTFLRENFE-----------------------------------------------------------------------------------------------------------------------------HIQHIVIDEAQNFRTED-----GGPGILWIFLDYFQ-----SHLDCSGLPPLS--------QYPREELTRIVRNADPIAKYLQKEMQVIR......................................................................................................................................................................................... 299
69 -11.300sp|Q9H611|PIF1_HUMAN ATP-dependent DNA helicase PIF1 OS=Homo sapiens GN=PIF1 PE=1 SV=2  ali   15  39........................................................................................................................................................PRWPLPVKRLSLPSTKPQLSEEQAAVLRAVLKGQSI-FFTGSAGTGKSYLLKRILGSL--PPTGTVATASTGVAACHIGGTTLHAFAGIGSGQ------------------------------------------------------------------------------------------APLAQCVALAQRPGVRQGWLNCQRL--------------------VIDEISM-VEADLFDKLEAGIQLIICGDFLQLPPVTKGSQPPRF---CFQKSWKRCVPVTLELTKVWRQADQTFISLLQAVRLGRCSDEV.................................................................................................................................................................................... 253
70 -11.100sp|Q08AF3|SLFN5_HUMAN Schlafen family member 5 OS=Homo sapiens GN=SLFN5 PE=1 SV=1  ali   12  106..........................................................................................................................................................................LTNKQYELLSKNLRKTRELFVHGLPGSGKTILALRIMEKIRNEPANILYICENQPLKKLVSFSKKNICQPVTRKTFMKNNFEHIQHII---------IDDAQNFRTEDGDWYGKAK---------------------------------------------------------------------------------------------FITQTARDG-----------PGVLWIFLDYFQ-----YHLSCSGLPPPS--------QYPREEINRVVRNAGPIANYLQQVMQEARQNPPPNLPPGSLV............................................................................................................................................................................ 293
71 -11.000sp|P18074|ERCC2_HUMAN TFIIH basal transcription factor complex helicase XPD subunit OS=Homo sapiens GN=ERCC2 PE=1 SV=1  ali   11  21...........................................................................................................................................................................QFSYMRELKRTLDAKGHGVLEMPSGTGKTVSLLALIMAYQRAYTKLIYCSRTVPEIEKVIEELRKLLNFYEKQEGEKLPFLGLALSSRKNLCIHPEVTPLRFGKDVDGKCHSLTASYVRAQYQHDTSLPHCRFYEEFDAHGREVPLPAGIYNL--------DDLKALGRRQGWCPYFLARYSILHANVVVYS-------------YHYLLDPKIADLVSKE-----LARKAVVVFDEAHNIDNVCIDSMSVNLTRRTLDRCQGNLETLQKTVL.............................................................................................................................................................................................................. 271
72 -10.700sp|Q9H0A0|NAT10_HUMAN N-acetyltransferase 10 OS=Homo sapiens GN=NAT10 PE=1 SV=2  ali   17  108...........................................................................................................................................................................LDQAKAVLKFIEGLRSTVALTAARGRGKSAALGLAIAGAVAFGYNIFVTSPSPDNLHTLFEFVFKGFDALQ-------------------YQEHLDYEIIQSLNPEFNKAVIRVNVFREHRQTIQ----------------------------------------------------------------------HPADAVKLGQAELVVIDEAA-AIPLPLVKSLLGPYLVFMA-------STINGYEGTGLSLKLIQQLRQQSAQSQVSTTAENKTT........................................................................................................................................................................................................ 299
73 -10.600sp|P0C7P3|SLN14_HUMAN Schlafen family member 14 OS=Homo sapiens GN=SLFN14 PE=2 SV=2  ali   15  121..........................................................................................................................................................................LIMEQSQLLSESLQKTRELFIYCFPGVRKTALAIKIMEKIKDKPKEILYVCESDSLKDFVTQQTT-------------------------------------------------------------------------------------------------CQAVTRKTFMQGEFLKIKHIVMDETENFCSKYGNW-------MKAKNITHPKAKGTGSEN-----LHHGILWLFLDPFQ----IHHADVNGLPPPSAQ-------FPRKTITSGIHCALEIAKVMKEEMKR........................................................................................................................................................................................... 298
74 -10.300sp|P51530|DNA2L_HUMAN DNA2-like helicase OS=Homo sapiens GN=DNA2 PE=1 SV=3  ali   17  139....EYFSLWCLMLTLEQSKDNKKNHQNIWLMPASEMEKSGSCIGNLIRMEHVKIVCDHNFQCKHGAIPVTNLMAGDRVIVSGEERSLFALRGYVKEINMTTVTCLLDRNLSVESTLFRLDQEEKNCDIDTPLGNLSKL............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 281
75 -10.300sp|Q8NFZ0|FBX18_HUMAN F-box only protein 18 OS=Homo sapiens GN=FBXO18 PE=1 SV=2  ali   19  60........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................RRWVHKEGFSGFKRYVTAAEDKELE-AKIAVVEKYNIRIPELVQRIFAEYILGTVHKAKGLEFDTVHVNLPQLPHFRVESFSEDEWNL-VAVTRAKKRLIM............................. 181
FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Liu T, Rojas A, Ye Y, Godzik A. Homology modeling provides insights into the binding mode of the PAAD/DAPIN/pyrin domain, a fourth member of the CARD/DD/DED domain family. Protein Sci. 2003 Sep;12(9):1872-81.