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Query: TM0017 TM0017 281898 Purified-2003-03-05, from T.maritima

Results of FFAS03 search in H.sapiens
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MRMERVVERVAVTGAEAVANAMRQIEPDVVAAYPITPQTPIVEYFARFVADGVVRTEMIPVESEHSAMSAVVGAAAAGARAMTATSANGLALMHEIVYIAASYRLPIVMPVVNRALSGPINIHCDHSDAMAERDSGWIQLFAETNQEAYDFTILAVRLAEHEDVRLPVMVNLDGFILSHGVEPVEFYPDELVKKFVGELKPMYPLLDTEHPVTWGPLDLYDYYFEHKRQQIEAMENVKKVFPEIAKEFEETFGRKYWFVEPYRMEDAEHVMVALGSTNSTIKYVVDELREEGYKVGSLKIWMFRPFPKEQLQELLNGRKSVVVLDRAVSFGAEAPLYEAVKSALYEVAARPMLGSYVYGLGGRDIKPEHIRKAFEDAINGNLIADEQRYLGLRELast
1 -16.000sp|Q96HY7|DHTK1_HUMAN Probable 2-oxoglutarate dehydrogenase E1 component DHKTD1, mitochondrial OS=Homo sapiens GN=DHTKD1 PE=2 SV=2  ali   39..............................................................SEEAVLGFEYGMSIESPKLLPGDFFNGAQIIFDTFISGGEAKSGIVILLSSCRIERFLQMCDSAEEGVDGDTVNMFVVHPTTPAQYFHLLRRQMVRNF----RKPLIVASPKMLLRLPAAVSTLQEMAPGTTFNPVIGD----------------------------------------------------------SSVDPKKVKTLVFCSGKHFYSLVKQRESLGAKKHDFAIIRVEELCPFPLDSLQQEMSKYKHVKDHEEPQNMGPWSFVSPRFEKQL.................................................. 283
2 -15.600sp|P11177|ODPB_HUMAN Pyruvate dehydrogenase E1 component subunit beta, mitochondrial OS=Homo sapiens GN=PDHB PE=1 SV=3  ali follow..  14  40..............NQGMDEELERDEKVFLLGEEVAQYDGAYKVSRGLWKKYGDKRIIDTPISEMGFAGIAVGAAMAGLRPICEFMTFNFSMIDQVINSAAKTYVPIVFRGPNGASAGVAAQHSQCFAAWYGHCPGLKVVSPWNSEDAKGLIKSAIRDNN----PVVVLENELMYGVPFEFPPEAQSKDFLI------------------PIGKAKIER---------------------------------------------QGTHITVVSHSRPVGHCLEAAAVLSKEGVECEVINMRTIRPMDMETIEASVMKTNHLVTVEGGWPQFGVG---AEICARIMEGPAFNFLDAPAVRVTGADVQVKDIIFAIKKTLN............... 358
3 -14.600sp|P29401|TKT_HUMAN Transketolase OS=Homo sapiens GN=TKT PE=1 SV=3  ali   13  22.............GQALAKLG--HASDRIIALDGDTKNSTFSEIFKKEHPDRFIECYI----AEQNMVSIAVGCATRNRTVFCSTFAAFFTRAFDQIRMAAISESNINLCGSHCGVSEDGPSQMALEDLAMFRSVTSTVFYPSDGVATEKAVELAANTKGICFIRTS-----ENAIIYNNNEDFQVGQAKVVLK----------------------------------------------------------------------KDDQVTVIGAGVTLHEALAAAELLKKEKINIRVLDPFTIKPLDRKLILDSARATKRILTVEDHYYEGGIGEAVSSAVVG................................................... 278
4 -14.300sp|P21953|ODBB_HUMAN(removed signalp:1-19) 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial OS=Homo sapiens GN=BCKDHB PE=1 SV=2  ali follow..  13  64.NSLAKDPTAVIFGEDVAFGGVFRCTVGLRDKY--TPLC------------------------EQGIVGFGIGIAVTGATAIAEIQFADYIFFDQIVNEAAKYRGSLTIRSPWGCVGHGALYHSQSPEAFFAHCPGIKVVIPRSPFQAKGLLLSCIEDKN----PCIFFEPKILYRAAAEEVPIEPYNIPLSQAEVIQ------------------------------------------------------------------EGSDVTLVAWGTQVHVIREVASMAKEKGVSCEVIDLRTIIPWDVDTICKSVIKTGRLLISEAPLTGGFASEISSTVQEECFLN-----LEAPISRVCGYDTDKWKCYDALRKMIN............... 372
5 -14.000sp|Q9H0I9|TKTL2_HUMAN Transketolase-like protein 2 OS=Homo sapiens GN=TKTL2 PE=1 SV=1  ali   11  13YKVGDKIATQKTYGLALAKLG--RANERVIVLSGDTMNSTFSEIFRKEHPERFIECII----AEQNMVSVALGCATRGRTIFAGAFAAFFTRAFDQLRMGAISQANINLIGSHCGVGEDGVSQMALEDLAMFRSINCTVFYPSDAISTEHAIYLAANTKGMCFIRTS-----ETAVIYTPQENFEIGQAKVVRH----------------------------------------------------------------------VNDKVTVIGAGVTLHEALEAADHLSQQGISVRVIDPFTIKPLDAATIISSAKATGRVITVEDHYREGGIGEAVCAAVSR................................................... 282
6 -13.500sp|P29401|TKT_HUMAN Transketolase OS=Homo sapiens GN=TKT PE=1 SV=3  ali   12  49........................................................................................................................................................................................................................................................................KDDQVTVIGAGVTLHEALAAAELLKKEKINIRVLDPFTIKPLDRKLILDSARATKRILTVEDHYYEGGIGEAVSSAVVGEPGITVTHLAVNRVPRSGKPAIDRDAIAQAVRGLITKA............. 173
7 -13.500sp|Q9H0I9|TKTL2_HUMAN Transketolase-like protein 2 OS=Homo sapiens GN=TKTL2 PE=1 SV=1  ali   15  53........................................................................................................................................................................................................................................................................VNDKVTVIGAGVTLHEALEAADHLSQQGISVRVIDPFTIKPLDAATIISSAKATGRVITVEDHYREGGIGEAVCAAVSREPDILVHQLAVSGVPQRGKTSISTRHIIAAVTLTLMK.............. 176
8 -13.100sp|P51854|TKTL1_HUMAN Transketolase-like protein 1 OS=Homo sapiens GN=TKTL1 PE=1 SV=2  ali follow..  13  283YRVGDKIATRKACGLALAKLG--YANNRVVVLDGDTRYSTFSEIFNKEYPERFIECFM----AEQNMVSVALGCASRGRTIFASTFAAFLTRAFDHIRIGGLAESNINIIGSHCGVGDDGASQMALEDIAMFRTIKCTIFYPTDAVS----TEHAVALAANAKGMCFITTRPETMVIYTPQERFEIGQAKVLRH---------------------------------------------------------------------CVSDKVTVIGAGITVYEALAAADELSKQDIFIRVIDLFTIKPLDVATIVSSAKATERIITVEDHYPQGGIGEAVCAAVSMDPDIQVHSLAVSGVPQSGKSEISARHIIVAVKCMLLN.............. 596
9 -13.000sp|A1L0T0|ILVBL_HUMAN(removed signalp:1-28) Acetolactate synthase-like protein OS=Homo sapiens GN=ILVBL PE=1 SV=2  ali   15  15..LHKVDKASVRHGGENVAAVLRAHGVRFIFTLVGGHISPLLVACEK------LGIRVVDTRHEVTAVFAADAARLSGTVGVAVTAGPGLTNTVTAVKNAQMAQSPILLLGGAASTLLQNRGALQAVDQLSLRPLCKFCVSVRRVRDIVPTLRAAMAAAQSGT-PGPVFVELPVDVLYPYFMVQKEMVPAKPPKGLVGRVVSWYLENYLANLFAGAWEPQPEGPLPLDIPQASPQQVQRCVEIL--------------------SRAKRPLMVLGSQALLTPTSADKLRAAVETLGV-------PC........................................................................................ 287
10 -8.800sp|Q96HY7|DHTK1_HUMAN Probable 2-oxoglutarate dehydrogenase E1 component DHKTD1, mitochondrial OS=Homo sapiens GN=DHTKD1 PE=2 SV=2  ali   11  50........................................................................................................................................................................................................................................................................KKVKTLVFCSGKHFYSLVKQRESLGAKKHDFAIIRVEELCPFPLDSLQQEMSKYKHVKDHEEPQNMGPWSFVSPRFEKQLACKLRLVRPPLPVPAVGIGTVHLHQHEDILAKTFA............... 169

FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Doctor KS, Reed JC, Godzik A., Bourne PE. The apoptosis database. Cell Death Differ. 2003 Jun;10(6):621-33. Review.