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Query: TM0005 TM0005 281886 Purified-2001-01-30, from T.maritima

Results of FFAS03 search in PDB1018
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MTVQQFIKKLVRLVELERNAEINAMLDEMKRLSGEEREKKGRAVLGLTGKFIGEELGYFLVRFGRRKKIDTEIGVGDLVLISKGNPLKSDYTGTVVEKGERFITVAVDRLPSWKLKNVRIDLFASDITFRRQIENLMTLSSEGKKALEFLLGKRKPEESFEEEFTPFDEGLNESQREAVSLALGSSDFFLIHGPFGTGKTRTLVEYIRQEVARGKKILVTAESNLAVDNLVERLWGKVSLVRIGHPSRVSSHLKESTLAHQIETSSEYEKVKKMKEELAKLIKKRDSFTKPSPQWRRGLSDKKILEYAEKNWSARGVSKEKIKEMAEWIKLNSQIQDIRDLIERKEEIIASRIVREAQVVLSTNSSAALEILSGIVFDVVVVDEASQATIPSILIPISKGKKFVLAGDHKQLPPTILSEDAKDLSRTLFEELITRYPEKSSLLDTQYRMNELLMEFPSEEFYDGKLKAAEKVRNITLFDLGVEIPNFGKFWDVVLSPKNVLVFIDTKNRSDRFERQRKDSPSRENPLEAQIVKEVVEKLLSMGVKEDWIGIITPYDDQVNLIRELIEAKVEVHSVDGFQGREKEVIIISFVRSNKNGEIGFLEDLRRLNVSLTRAKRKLIATGDSSTLSVHPTYRRFVEFVKKKGTYVIFLast
1 -135.0004b3f_X mol:protein length:646 DNA-BINDING PROTEIN SMUBP-2  ali model follow..  33  2AAVESFVTKQLDLLELERDAEVEERRSWQENISLKELQSRGVCLLKLQVSSQRTGLGRLLVTFEPAALPSNSFTSGDIVGLYDAANEGSQATGILTRVTQKSVTVAFDESHDDRENSYRLLKLANDVTYRRLKKALIALKKYHSGPASSLIESAPSPASEIHPLTFFNTCLDTSQKEAVLFALSQKELAIIHGPPGTGKTTTVVEIILQAVKQGLKVLCCAPSNIAVDNLVERLALKQRILRLGHPARLLESIQQHSLDAVLARSDSAQIVADIRKDIDQVFVKN----------------------------------KKTQDKREKSNFRNEIKLLRKELKEREEAAMLESLTSANVVLATNTGASAKLLPESYFDVVVIDECAQALEASCWIPLLKARKCILAGDHKQLPPTTVSHKAAGLSLSLMERLAEEYGARVRTLTVQYRMHQAIMRWASDTMYLGQLTAHSSVARHLLRDLPGV--------AATEETGVPLLLVDTAGCG-LFELEEEDEQSKGNPGEVRLVSLHIQALVDAGVPARDIAVVSPYNLQVDLLRQSLVHELEIKSVDGFQGREKEAVILSFVRSNRKGEVGFLAEDRRINVAVTRARRHVAVICDSRTVNNHAFLKTLVEYFTQHGEVRT. 636
2 -130.0002xzl_A mol:protein length:802 ATP-DEPENDENT HELICASE NAM7  ali model follow..  27  186.DAYEYQRSYGPLIKLEADYDKQLKESQALE-------------ISVSWSLALNNRHLASFTLSTFESNELKVAIGDEMILWYSGMQHPDWEGRLPNSFQDTFTLELKPSKTHLTTGFTAEFIWKGTSYDRMQDALKKFAIDKKSISGYLYYKSFDVPLPKEFSIPNFAQLNSSQSNAVSHVL-QRPLSLIQGPPGTGKTVTSATIVYHLSKIHKRILVCAPSNVAVDHLAAKLRDGLKVVRLTAKSRVESSVSNLALHNLVGRGAK---------------------------------------------------GELKNLLKLKDEVGELSASDTKRFVKLVRKTEAEILNKADVVCCTCVGAGDKRLDT-KFRTVLIDESTQASEPECLIPIVKGKQVILVGDHQQLGPVILERKAAGLKQSLFERLISL-GHVPIRLEVQYRMNPYLSEFPSNMFYEGSLQNGVTIEQRTVPNSKFPWPIRGI----------PMMFWANYG----REEISANGTSFLNRIEAMNCERIITKLFRDGVKPEQIGVITPYEGQRAYILQYMQMKVEVASVDAFQGREKDYIILSCVRANEQQAIGFLRDPRRLNVGLTRAKYGLVILGNPRSLARNTLWNHLLIHFREKGCLVE. 788
3 -123.0006ej5_A mol:protein length:637 Regulator of nonsense transcripts 1  ali model follow..  26  10.DAYQYQNIFGPLVKLEADYDKKLKESQTQDNITVRWDLG-----KRIAYFTLPKTDSGNEDLVIIWLRDMRLMQGDEICLRYKGDLAPLWKGIVPDNYGDEIAIELRSSVGEVTHNFQVDFVWKSTSFDRMQSALKTFAVDETSVSGYIYDVIIKCQLPKRFTAQGLPDLNHSQVYAVKTVL-QRPLSLIQGPPGTGKTVTSATIVYHLARQGNPVLVCAPSNIAVDQLTEKIHQGLKVVRLCAKSRIDSPVSFLALHNQIRNMDSMPELQKLQQ--------------------------------------------------LKDETGELSSADEKRYRALKRTAERELLMNADVICCTCVGAGDPRLAKMQFRSILIDESTQATEPECMVPVVLGKQLILVGDHCQLGPVVMCKKAAGLSQSLFERLVVL-GIRPIRLQVQYRMHPALSAFPSNIFYEGSLQNGVTAADRVKKGFDFQWP----------QPDKPMFFYVTQG----QEEIASSGTSYLNRTEAANVEKITTKLLKAGAKPDQIGIITPYEGQRSYLVQYMQQEVEIASVDAFQGREKDFIILSCVRANEHQGIGFLNDPRRLNVALTRARYGVIIVGNPKALSKQPLWNHLLNYYKEQKVLVE. 623
4 -119.0002wjv_A mol:protein length:800 REGULATOR OF NONSENSE TRANSCRIPTS 1  ali model follow..  26  183EDAYQYQNIFGPLVKLEADYDKKLKESQTQD--------------NITVRWDLGLNKKRIAYFTLPKTDDMRLMQGDEICLRYKGDLAPLWKGIVPDNYGDEIAIELRSSPVEVTHNFQVDFVWKSTSFDRMQSALKTFAVDETSVSGYIYDVIIKCQLPKRFTAQGLPDLNHSQVYAVKTVL-QRPLSLIQGPPGTGKTVTSATIVYHLARQGNPVLVCAPSNIAVDQLTEKIHQGLKVVRLCAKSRIDSPVSFLALHNQIRNMDSMPELQKLQQ--------------------------------------------------LKDETGELSSADEKRYRALKRTAERELLMNADVICCTCVGAGDPRLAKMQFRSILIDESTQATEPECMVPVVLGKQLILVGDHCQLGPVVMCKKAAGLSQSLFERLVVL-GIRPIRLQVQYRMHPALSAFPSNIFYEGSLQNGVTAADRVKKGFDFQWPQ----------PDKPMFFYVTQG----QEEIASSGTSYLNRTEAANVEKITTKLLKAGAKPDQIGIITPYEGQRSYLVQYMQQEVEIASVDAFQGREKDFIILSCVRANEHQGIGFLNDPRRLNVALTRARYGVIIVGNPKALSKQPLWNHLLNYYKEQKVLVE. 786
5 -116.0005mzn_A mol:protein length:749 Helicase SEN1,Helicase SEN1  ali model follow..  23  58.SPADYQKVMKPLLLLESWQGLCSSRDREDYKPFSII---------VGNRTAVSDFYDVYASVAKQVIQDCGISESDLIVMAYLPDFRPDKRLTLKNTKGGNVDVTLRSKFLTLRSEIYCVKVMQMTTIEREYSTLEGLEYYDLVGQILQAKPSPPVDAAEIETVKKSYKLNTSQAEAIVNSVSKEGFSLIQGPPGTGKTKTILGIIGYFLSTKNKILICAPSNAAVDEICLRLKSGVQLVRVGRSDVVNVAIKDLTLEELVDK----------------------------------------------------------RIGERNYGSGSKNSVNYRNRDLDRRNAQAHILAVSDIICSTLSGSAHDVLATMKFDTVIIDEACQCTELSSIIPLRYGKRCIMVGDPNQLPPTVLSGAASKYNQSLFVRMEK--NSSPYLLDVQYRMHPSISKFPSSEFYQGRLKDGPGMDILNKRPWHQL------------EPLAPYKFFDIISG---RQEQNAKTMSYTNMEEIRVAIELVDYLFRKFDNTGKIGIISPYREQMQKMRKEFARSIDFNTIDGFQGQEKEIILISCVRADDKSSVGFLKDFRRMNVALTRAKTSIWVLGHQRSLAKSKLWRDLIEDAKDRSCLAY. 700
6 -103.0005ean_A mol:protein length:1059 DNA replication ATP-dependent helicase/nuclease DNA2  ali model follow..  26  443....KYFSLWCLMLTLESQSDNRKTHQSIWLTPASELEESGNCVGNLVRTEPVSRVCDHNFQRKNGPMPATNLMAGDRIILSGEERKLFALKGYVKKMNKAAVTCLLDRNLSTATTVFRLDREERHGDISTPLGNLSKLMESTKRLRELIIDFREPQHDAKDTVANILKGLNKPQRQAMKRVLLSKDYTLIVGMPGTGKTTTICALVRILSACGFSVLLTSYTHSAVDNILLKLAKKVGFLRLGQSHKVHPDIQKFTEEEICRSRSIASLAH-----------------------------------------------------------------------------LEELYNSHPIVATTCMGINHPIFSRKTFDFCIVDEASQISQPVCLGPLFFSRRFVLVGDHQQLPPLVVNREARGMSESLFKRLER-NESAVVQLTVQYRMNRKIMSLSNKLTYAGKLECGSDRVANAVLALPNLKDARLSLQAGVLEPDNPVCFLNTDKVP---APEQVENGGVSNVTEARLIVFLTSTFIKAGCSPSDIGVIAPYRQQLRIISDLLARMVEVNTVDKYQGRDKSLILVSFVRSNEDGTLGLLKDWRRLNVALTRAKHKLILLGSVSSLKRFPPLGTLFDHLNAEQLILDL 1047
7 -80.1005wwp_B mol:protein length:600 ORF1ab  ali model follow..  18  100.TGSPSIVEFNRLATCDWTESGDYTLANTTTEPLKLFAAE-----TLRATEEASKQSYAIATIKEIVGERQLLLVWEAGKSKPPLNRNYVFTGYHITKNSK---VQLGEYIFERIDYSDAVSYKSSTTYKLTVGDIFVLTSHSVATL-TAPTIVNQERYVKITGLYPTITVPEEFASHVANFQKYSKYVTVQGPPGTGKSHFAIGLAIYY--PTARVVYTACSHAAVDALCEKAFKYLNI-------------------------------------------------------------------------------------------AKCSRIIPAKARVECYDRFKVNETNSQYLFSTINA-----LPETSADILVVDEVSMCTNYDLSIINARAKHIVYVGDPAQLPAPRTLLTRGPENFNSVTRLMCNLG-PDIFLSMCYRCPKEIVSTVSALVYNNKLLAKKELSGQCFKIL-------------------------------YKGNVTHDASSAINRPQLTFVKNFITANPA----WSKAVFISPYNSQNAVSRSML--GLTTQTVDSSQGSEYQYVIFCQTADT-----AHANNINRFNVAITRAQKGILCVMTSQALFESLEFTELSFTNYK....... 598
8 -79.7005mqf_U mol:protein length:1485 Intron-binding protein aquarius  ali model follow..  21  801.........................................................................................................................................................................QFTHTQIEAIRAGM-QPGLTMVVGPPGTGKTDVAVQIISNIYHNEQRTLIVTHSNQALNQLFEKIMAERHLLRLGHGEEELETEKDFSRYGRVNYVLARRRWEEYISKVKNKGSTLPDVTEVSTFFPFHEYFANAPQPIFKGRSYEEDMEIAEGCFRHIKKIFTQLEEFRELLRSGLDRSKYLLVKEAKIIAMTCTHAALKR-LGFKYDNILMEEAAQILEIETFIPLLLQKRWIMIGDHHQLPPVIKNMAFQNMEQSLFTRFVRV-GVPTVDLDAQGRARASLCNLYNWRYKN--LGNLPHVQLL------------PEFSTANAGLLYDFQLINVEDFQGVGESE-PNPYFYQNLGEAEYVVALFMYMCLLGYPADKISILTTYNGQKHLIRDIINRRNKVTTVDRFQGQQNDYILLSLVRTR---AVGHLRDVRRLVVAMSRARLGLYIFARVSLFQNCFELTPAFSQLTARPLHLHI 1332
9 -69.3003jb9_X mol:protein length:1284 Pre-mRNA-splicing factor cwf11  ali model follow..  14  726.........................................................................................................................................................................TYNDKQLESILRGS-QPGLTMVNGPTRCGKHVLVCKLLEVLQDTNDRTVVLSDSNFSMNTLFTLLEKQGHLLYLSDEGKDETLERYGTLSSWISKLPG-REIGRLAASIQAPGSHDASPDTALYFRDAYIKRLDKSKRPIETYNKDNFFDYATKLYGELEYMFQQLEEIRGLLRYYEDQELYALCQQSRIIGCTWTSLSTRL--GFCFNNLIVMNSQNISESSITSILLSNDRLVLLGNQYLTSGNQDIN--NTSNGSLFKRLRYL-KSRIIDLNTQYNVRESISSL--SSIYPLDIKTVDSSPNKRLDY-------------GNSGFAHEVQFINVGAFKGSQETE-PVSGYKQNLGEAEYAVALFQYMRMLGYPTNEIVICTLYESQVSLLNEIISVRAFVGTVEKLPSDKRNFVIFTTVESKE---ASDHWNPKTFYKAFSACSYGLYVLCNRDLFRSTRGLEKLWNEIEKTPDKLLL 1242
10 -36.1004n0n_A mol:protein length:423 Replicase polyprotein 1ab  ali model follow..  16  153...........................................................................................................................................................................TLKGVVVNKALKNAAASEYVEGPPGSGKTFHLVKDVLAV---VGSATLVVPTHASMLDCINKLKQAGADPYFVVPKYTVLDFPRPGSGNITVRLPQ---------------------------------------------------------------------------------------------------------VGTSEGETFVDEVAY-FSPVDLARILTQGRVKGYGDLNQLGCVGPA--------SVPRNLWLRHFVSLEPLRVCHRFGAAVCDLIKG-IYPYYEPAPHTTK----------------------------------------------------------------VVFVPNPDFEKGVVITAYHKD---------RGLGHRTIDSIQGCTFPVVTLRLPTPQS-------LTRPRAVVAVTRASQELYIYDPFDQLSG.................... 413
11 -34.4003wrx_C mol:protein length:451 Replicase large subunit  ali model follow..  13  148............................................................................................................................................................................RRLLKDGEPHVSSAKVVLVDGVPGCGKTKEILSRV-----NFEEDLILVPGRQAAEMIRRRA----------------------------------------------------------------------------------------------------------------NASGIIVATKDNVRTVDSFLMNYGKGARCQFKRLFIDEGLML-CVNFLVEMSLCDIAYVYGDTQQIPYINRVTGF-----PYPAHFAKLEVDEVETRRTTLRCPADVTHFLNQRYEGHVMCTSSEKKSVSQEMVSGA------------------------------------------------------ASINPVSKPLKGKILTFTQSDKEALLSR--GYADVHTVHEVQGETYADVSL--VRLTPTPVSIIARDSPHVLVSLSRHTKSLKYY----TVVMDPLVSIIRDLERVSSYLLD. 442
12 -26.4005ld2_D mol:protein length:609 RecBCD enzyme subunit RecD  ali model follow..  14  150.........................................................................................................................................................................DEINWQKVAAAVALTRR-ISVISGGPGTGKTTTVAKLLAALIQMADRIRLAAPTGKAAARLTESLGKALRQLPLTDEQKKRIPEDASTLHRLLGAQPGSQRLRHHAGN------------------------------------------------------------------------------------------------PLHLDVLVVDEASMPMMSRLIDALPDHARVIFLGDRDQLASVICAYANAGFTAERARQLSRLTGDSLCLLQKSYRFGSDIGQL-AAAINRGDKTAVKTVFQQDFTDIEKRLLQSGEDYIAMLEEALA--YLDLLQARAEPDREGPFGVAGLNERIEQFMVMIARNDSALGLFNGDIGIALDRGQGTRVWFAMPDGNIK--TVHKSQGSEFDHAALILPSQRTP-----VVTRELVYTAVTRARRRLSLYADERILSA.................... 589
13 -23.4003upu_A mol:protein length:459 ATP-dependent DNA helicase dda  ali model follow..  12  19.........................................................................................................................................................................DLTEGQKNAFNIVMKKKHHVTINGPAGTGATTLTKFIIEALISTGEGIILAAPTHAAKKILSKLSGKEASTIH--------------ILKINPVTYEENVLFEQKEVP-----------------------------------------------------------------------------------------------DLAKCRVLICDEVSM-YDRKLFKILLSWCTIIGIGDNKQIRPV-----DPGENTAYISPFFTHKDFYQCELTEVKRSNAPIIDVATDNYFSIVKSLDDLFENRVMAFTNKSVDKLNSIIRKKIFETDKIIVMQEPLFKTYKIDGKPVSEIIFNNGQLVRIIEAVETYGDDEYYREKIKIISSFNLFLGKTAETYKNKVKALTFHKAQGMSVDRAFIYTPCIHYADV---ELAQQLLYVGVTRGRYDVFYV............................ 453
14 -21.2003e1s_A mol:protein length:574 Exodeoxyribonuclease V, subunit RecD  ali model follow..  16  189.........................................................................................................................................................................GLSEEQASVLDQLAGHR-LVVLTGGPGTGKSTTTKAVADLAESLGLEVGLCAPTGKAARRLGEVTGRTASTVH-------------------------------------------------------------------------------------------------------------------RLLGYGPQGFRHNHLEPAPYDLLIVDEVSMMLMLSLLAAVPPGARVLLVGDTDQLPPVDAGLPLLALAQA----------APTIKLTQVYRQKNPIIQAAHGLLHGEAPAWGDKRLNLTEIEPDGGARRVALMVRELGGPGAVQVLTPMRKGPLGMDHLNYHLQALFNPGEGGVRVVQTKNDYNNEIFNGTLGMVLKFDGNVVELTGAELFNLQLGTVHRAQGSEWGTVLGVLHEAHM-----PMLSRNLVYTALTRARDRFFSAGSASAWQI.................... 546
15 -18.5002is1_A mol:protein length:680 DNA helicase II  ali model follow..  15  2..................................................................................................................................................................DVSYLLDSLNDKQREAVAAP--RSNLLVLAG-AGSGKTRVLVHRIAWLMSVENSIMAVTFTNKAAAEMRHRIGQ------MGTSQGGMWVGTFHGLAHRLLRAHHMDANLPQDFQILDSEDQLRLLKRLIKAMNLDEKQWPPRQAMWYINSQKDEGLRPHHIQSYGNPVEQTWQKVYQAYQEACDRAGLVDFAELLLRAHELWLNKPHILQRERFTNILVDEFQDTNNIQAWIRLLAGGKVMIVGDDDQ---SIYGWRGAQVENIQFLN--DFPGAETIRLEQNYRSTSNILSAANALIENNNGRLGKKL------------------------------------TDGADGEPISLYCAFNELDEARFVVNRIKTWQDNGGALAECAILYRSNAQSRVLEEALQASMPYRIYGGFERQEKDALSYLRLIVNRNDDAAF---ERVVNTP-TRG------IGDRTL-------DVVRQTSRDRQLTL.. 437
16 -18.4004c2t_A mol:protein length:745 DNA HELICASE II  ali model follow..  14  2...............................................................................................................................................................TSSAGPDLLQALNPTQAQAADHF--TGPALVIAG-AGSGKTRTLIYRIAHLIGHYGEILAVTFTNKAAAEMRERLVPGAGDLWMSTFHSAGVRILRTYGEHIGLRRGFVIYDDDDQLDIIKEVMGSIPGIGAETQPRVIRGIIDRAKSNLWTPDDLDRSREPFISGLPRDAAAEAYRRYEVRKKGQNAIDFGDLITETVRLFKEVPGVLDKV--QNKAKFIHVDEYQDTNRAQELTRLLASRNLLVVGDPDQ---SIYKFRGADIQNILFQK--DYPDAKVYMLEHNYRSSARVLEAANKLIENNTERLDKTL------------------------------------PVKEAGQPVTFHRATDHRAEGDYVADWLTRLHGEGRAWSEMAILYRTNAQSRVIEESLRVQIPARIVGGYDRRERDILAYARLALNPADDVAL---RRIIGRP-RRG------IGDTAL-------QKLMEWARTHHTSV.. 444
17 -17.2001pjr_A mol:protein length:724 PCRA  ali model follow..  16  8......................................................................................................................................................................LLAHLNKEQQEAVRTT--EGPLLIMAG-AGSGKTRVLTHRIAYLMAEKHNILAITFTNKAAREMRERVQSAAEDVWISTFHSMCVRILRRDIDRILDPTDQLSVMKTILKEKN-----IDPKKFEPRTILGTISAAKNELLPPEQFAKRASTYYEKVVSDVYQEYQQRLLR-------------NHSLDFDDLIMTTLFDRVPDVLHQYKFQYIHIDEYQDTNRAQTLVKKLAEQNICAVGDADQ---SIYRWRGADIQNILFER--DYPNAKVILLEQNYRSTKRILQAANEVIEHNVNRKPKRI------------------------------------TENPEGKPILYYEAMNEADEAQFVAGRIREAVERGRRYRDFAVLYRTNAQSRVMEEMLKANIPYQIVGGYDRKEKDILAYLRVIANPDDDLSL---LRIINVP-KRG------IGASTI-------DKLVRYAADHELSL.. 441
18 -16.7001uaa_A mol:protein length:673 PROTEIN (ATP-DEPENDENT DNA HELICASE REP.)  ali model follow..  13  2.........................................................................................................................................................................RLNPGQQQAVEFV--TGPCLVLAG-AGSGKTRVITNKIAHLIRGCGHIAAVTFTNKAAREMKERVGQ------LGRKEARGLMISTFTLGLDIIKREYAALGMKANFSLFDDTDQLALLKELTEGLIEDDKVLLQQLISTISNWKNDLKTPSQAAASAIGERDRIFAHCYGLYDAHLKACNVLDFDDLILLPTLLLQANEEVRKQNKIRYLLVDEYQDTNTSQELVKLLVGARFTVVGDDDQ---SIYSWRGARPQNLVLSQ-----ALKVIKLEQNYRSSGRILKAANILIANNPHVFEKRL------------------------------------SELGYGAELKVLSANNEEHEAERVTGELIAHHVNKTQYKDYAILYRGNHQSRVFEKFLQNRIPYKISGGFSRPEKDLLAYLRVLTNPDDDSAFL---RIVNTP-KRE------IGPATL-------KKLGEWAMTRNKSM.. 432
19 -16.6003u44_A mol:protein length:1232 ATP-dependent helicase/nuclease subunit A  ali model follow..  13  5....................................................................................................................................................................KPADSTWTDDQWNAIVSTGQD---ILVAAAAGSGKTAVLVERMIRKITAEERLLVVTFTNASAAEMKHRIAEALQVLK-TEGELIGDEVLDELFEDLVDRYTTDRHDLDLQFLVKQVYEYSRSHPNPEAWLESFVHLYDVSEKSAIEPAVSFKRAKAVKGDEFDPALLDEATDLRNGAKKLAAKQEKSIIDFSDLILTAENDKGEREPSEAQFHEVLVDE-TNLVQESILQLVTSTGNLFMVGDVKQAEPLLFLSKYKRFTES------GEGTGRKIDLNKNFRSRADILDSTNFLF--------KQLMGGKIGEVDYDEQAELKLGAAYPDNDETETELLLIDNAEDTDASEEAEELETVQFEAKAIAKEIRKLISSPIQYRDIVILLRSMPWAPQIMEELRAQVYANLTSGYFEAVEVAVALSVLKDNPYQDIPLASVLRSPIVGADENELSLIRLEN----KKAPYYEAMKDYLAAGD..... 682
20 -16.3005mbv_B mol:protein length:1181 RecBCD enzyme subunit RecB  ali model follow..  13  1.........................................................................................................................................................................GMSDVAETLDPLRLPLQGERLIEASAGTGKTFTIAALYLRLLLGLEELLVVTFTEAATAELRGRIRSNIRMLN-KGPQALLRDINRYLQGEAPVIKAPPPDDETLASRHAQIVARIDTVKQQWRDAVGELDALIESSGIDRRKFNRSNQAKWIDKISAWAEEETNRETVAREKRRRGELGFDDMLSRLDSALRSESGEVLAAAIRTRFPVAMIDE--QDTDPRRIWHHQPETALLLIGDPKQ---AIYAFRGADIFTYMKAR---SEVHAHYTLDTNWRSAPGMVNSVNKLF--SQTDDAFMFREIPFIPVKSAGKNQALRFVFKGETQPAMKMWLM--------EGESCGVGDYQSTMAQVCAAQIRDWLQAGVRASDISVLVRSRQEAAQVRDALTLL----EIPSVYLSNRDSVFETLEAQEMLWLLQAVERENTLRSALATSMMGLNALDIETLNNDEHAWDVVVEEFDG....... 648
21 -16.1005fhd_A mol:protein length:433 Uncharacterized protein  ali model follow..  15  5.........................................................................................................................................................................ILTEEMQKIMNLIQDDENNVFVTGKAGSGKTTFLKYLIEKS---GKNCIVAAPTGIAAINAGGVTLHSLFGIPFGPITP------------------------------------------------------------------------------------------YDRLENKFSEYKVELLLKMELL--------------------IIDEISM-VRPDILDTIDRGVQVVMFGDLFQLPPVTKKQEREILSDFFNALVFKRTGFHIVELTKIFRQTEPLNNIRNYQVTSDELDLLSELKDRKISSSYDNEYIHICTHKADVEKINADKLGEQEIRNYDIVIKDKFPESSIPCDLHLKLVMSLVNDSLKGYYNGMLGIVTALEDNVITVRMDNGRTIKFETIHKSQGLTFDKIIIHVSHTFCPG---------QLYVALSRCRTGIVSDATKQMIIPEYALIDFERAYKSEG..... 425
22 -14.4005fhh_A mol:protein length:442 ATP-dependent DNA helicase PIF1  ali model follow..  13  7.........................................................................................................................................................................QLSEEQAAVLRAVLKGQSI-FFTGSAGTGKSYLLKRILGSL--PPTGTVATASTGVAACHIGGTTLHAFAGIGSGQ------------------------------------------------------------------------------------------APLAQCVALAQRPGVRQGWLNCQRL--------------------VIDEISM-VEADLFDKLEAGIQLIICGDFLQLPPVTKGSQPPRFCFQ--SKSWKRCVPVTLELTKVWRQADQLQAVRLGRCSDEVTRQLQATASHKVGRDGIVATRLCTHQDDVALTNE----LQELPGKVHRFEAMDSNPELASTLDAQCPVSQLLQLKSRGLVNGARGVVVGFEAEGGQLLSRQQLPLQLASIHKSQGMTLDCVEISLGRVFASGQA----------VALSRARSGLRVLDDPMAVRCDPRVLHFYATLRRG...... 418
23 -13.4004a15_A mol:protein length:620 ATP-DEPENDENT DNA HELICASE TA0057  ali model follow..  11  3.........................................................................................................................................................................ENRQYQVEFLRSSLQKSYGVALESPTGSGKTMALKSALQYSSERKLKVLYLVRTNSQEEQVIKELRSLSSTMKI--RAIPMQGRVNMCILYRMVDDLHEINAESLAKFCNMKKREVMAGNEAACPYFNFKIRSDETKRFLFDELPTA----------------EEFYDYGERNNVCPYESMKAALPDADIVIAPYAYFLNRSVAEKFLSVIILDEA------------------------HNLPDIGRSIGSFRISVESLNRADREASQKIHVSDLIEMIRSALQSMVSERCGKGDMRIMNKRSEREIRSLLNYLYLFGEYVENEKEKVGKVPFSYCSSVASRIIAFSDQDEEKYDGGYMQAACLDPSGILEVLKESKTIGTLDPFDFYSDITPENRYIAYYDGVSSKYDTLDEKELIEDIILKVKKNTIVYFPSYSLMDRVENRVSFEHMK--EYRGIDQKELYSMLKKFRRDHGTIFAV 501
24 -12.6005n8o_A mol:protein length:1756 DNA helicase I  ali model follow..  15  928.................................................................................................................................TGLLVSRASYEAEKSILRHILEGKEAVTPLMERVPGELMETLTSGQRAATRMILETSDFTVVQGYAGVGKTTQFRAVMSAV-SERPRVVGLGPTHRAVGEMRS------------------AGVDAQTLASFLHDTQLQQRSGETPDFSNTL--------------------------------------------------------------------------------------------------FLLDESSMNTEMARAYALIAGGRAVASGDTDQLQAI-----APG---QSFRLQQTRSAADVVIMKEIVRQTPELRE-AVYSLINRDVERALSGLESV---------KPSQVPRLEGAWAPEHSVTEFSHSQEAKLAEAQQKAMLKGEAFPDIPMTLYEAIVRDYTGREQTLIVTHLNEDRRVLNSMIHDARE-------AGEKEQVMVPVLNTANKNPDALALVDNVYHRIAGISKDDGLITLGNTRLISPREAVAEGVTLYTPDKIRVG. 1340
25 -12.5003crv_A mol:protein length:551 XPD/Rad3 related DNA helicase  ali model follow..  11  2........................................................................................................................................................................VKLRDWQEKKVIEGLRNNFLVALNAPTGSGKT---LFSLLVSLEVKPKVLFVVRTHNEFYPIYRDLTKNITFSFLVGKPSSYAEKGAESEDIPCKYCELKGSIVEVKTDDSPLSLV------------------------------------------------KKLKKDGLQDKFCPYYSLLNSLYKADVIALTYPYFFIDRYRDLREYMIVIDEAHNLDKVNELEERSLSEITI-----QMAIKQSKSEESRRILSKLLNQLREVVLPVIKNPEISYYLNLLNDNELSIILMSGTLPPREYMEKVWGIKRNMLYLDVERE-------------IQKRVSGSYECYIGVDVTSKYDMRSDNMWKRYADYLLKYFQAKANVLVVFPSYEIMDRVMSRISLPSEDSSVEDLYSANNKVLIGSVGKGKLAEGIELRNNDRSL--------SDVVIVG........................... 470
26 -12.5003dmn_A mol:protein length:174 Putative DNA helicase  ali model follow..  16  2...........................................................................................................................................................................................................................................................................................................................................................................................................................................................NASYRSTQQITDFTKE-------------------------------------------ILVNGEAVTAFDRQGDLPNVVVTPNFEAGVDQVVDQLAMNDSERDTTAIIGKSLAECEALTKALKARVIVVPSFLAKGLEFDAVIVWNANQENYQR----DERQLLYTICSRAMHELTLVAVGSL-------SPLLARVNHA...... 166
27 -12.3005h8w_A mol:protein length:597 ATP-dependent DNA helicase Ta0057  ali model follow..  11  1......................................................................................................................................................................................MQKSYGVALESPTGSGKTMALKSALQYSSERKLKVLYLVRTNSQEEQVIKELRSLSSTMKI----------------IPMQGRVNMCILYRMVDDLHEINAESLAKFCNMKKREVMAGNEAACPYFNFKIRSDETKRFLFDELPTA----EEFYDYGERNNVCPYESMKAALPDADIVIAPYAYFLNRSVAEKFLIVIILDEA------------------------HNLPDIGRSIGSFRISVESLNRADREASQKIHVSDLIEMIRSALQSMVSERIMNKRSEREIRSLLNALYLFGEYVENEKEKVGKVPFSYASSVASRIIAFSDQDEEKYAAILSPEDGGYMQAAALDPSGILEVLKESKTIGTLDPFD----FYSDITGFEIPFKKIGEFPPENRYIAIEDIILKVKKNTIVYFPSYSLMDRVENRVSFEHMK---EYRGIDQKELYSMLKKFRRDHGTI.. 480
28 -12.1004gl2_A mol:protein length:699 Interferon-induced helicase C domain-containing protein 1  ali model follow..  10  7.........................................................................................................................................................................QLRPYQMEVAQPALEGKN-IIICLPTGCGKTRVAVYIAKDHLDKPGKVIVLVNKVLLVEQLFRKEFQPFLKK--------------------------------------------------------------------------------------------WYRVIGLSGDTQLKISFPEVVKSCDIIIST-ENGEDAGVQLSDFSLIIIDECHHTNKEAVYNNIMRNNRLKKENKPVIPLPQILGLTAS--QAKAEEHILKLCANDAFTIKTVKENLDQLKNQIQEPCKKRMIDAYTHLETFYNEEKDKKFAVIEDDLKKPLKLDETDRFLMTLFFENNKMLKRLAENPEYENEKLTKLRNTIMEQYTRTEESARGIIFTKTRQSAYALSQWITENEQKEVISKFRTGKINLLIATTVAEE-----GL--DIKECNIVIRRARADYVLVAHSGSGVIERETVNDFREKMMYKAIHCV 543
29 -12.1002vl7_A mol:protein length:540 XPD  ali model follow..  10  1...................................................................................................................................................................MEVLKLQLRQWQAEEAINALKHGKTLLLNAKPGLGKT---VFVEVLGMQLKKKVLIFTRTHSQLDSIYKNAKLGLKTGFLIGKSAS----------------------------------------------------YAQGDEEPDEINCSKCRLKDKIKTIEDKEPSKLIEEFKDAVDYCPYYSLRANLKDKDVIAMTYPYLFQKPIRNSVFYLIVIDEAHNLLEADKWFTRKISRKML---EIVERLNRIDAKKVKDYINLLIDYMSKLIKDVKVPSDVNQLIEDALNVKTFKVLMSGTLPESLTLTNSYKIVVNESYGRGEYYY-----------------------CPNVTSELRKRNSNIPIYSILLKRIYEN--SSKSVLVFFPSYEMLESVRIHLSGIPVIEENKKTR-KTGKYLVMLVMRAKESEGVEFREKENLFES--------LVLAGLPYPNVSDDMVRKRIERLSKL...... 481
30 -11.8005jaj_A mol:protein length:681 LGP2  ali model follow..  12  9.........................................................................................................................................................................ELHGYQLEAVAPALRGRN-SIVWLPTGAGKTRAAVHVCRRHLERGGRVAVLVNKVHLVQQHLEKEFHVLRD---------------------------------------------------------------------------------------------AFKVTAVSGDSSHKCFFGQLAKGSDVVICTLSGEEEARVELTDFSLLVIDECHHTQKEAVYNKIMLSYLQKKLSGQRDL-PQILGLTAS--FEGAVEHILQICANDTEVIASAQEHAQHLQSHVPQPTKQYDLCQEREQDPDTVRMMDAFQCLQQFYADKRDTKDPTERFLATTFEENRATLQALAGDQRYENPRLSKLEEILQEHFQPPGSSRGI-VFTKTRQSAHSLLSWLQDNEQQDVITLFRYGELNLLFSTSVAEE-----GL--DIPECNIVVARAQNSMYSV............................ 486
31 -11.7005jc3_A mol:protein length:701 Melanoma differentiation associated protein-5  ali model follow..  12  7.........................................................................................................................................................................TLRDYQMEVAKPALNGEN-IIICLPTGSGKTRVAVYITKDHLDKQGKVIVLVNKVPLVEQHLRKEFNPFLKHWYQVIGLSGDSELKISFPEVVKRYD--------------------------------------------------------------------------------------IICTAQILENSLLNAEDESVRLSDFSLIIIDQCHHTQKEGVYNNIMR-RKQAKENKPLIPQPQILGLTAS--NSKAEEHILKICANDACRIMTVKEHASQLKNQVKE--YEQWVIREERRAAKEEKRKERVCAEHLKKYNDALQINDTIRMVDAYN-AKKKQLKELARKPEYDNEKLMKLRNTLMEEFTKTEEPRGI-IFTKTRQSALALYHWIMDNEQREVIDKFRGGSINLLIATTVAEE-----GL--DIKECNIVIRRARADALVASSGSGAVEREDVNIFRENMMYK...... 537
32 -11.6005vha_A mol:protein length:870 DEAH (Asp-Glu-Ala-His) box polypeptide 36  ali model follow..  11  64.............................................................................................................................................................................GMQKELVNMIDNHQVTVISGETGCGKTTQVTQFILDNYIERGKIVCTQPRRISAISVAERVAAERA--SCGNGNSTGYQIR---LQSRLPR------------------------------------------------------------------------------------------KQGSILYCT-TGIILQWLQSSSVSHIVLDEIHENLQSDVLMTVVK-----LLSYRPDLKVVLMS---ATLNAEKFSEYFGNCP----MIHIPGFTFPVVEYLLEDIIEKIRYVPEQKEHRSQFKKGFMQGHVNRQEKYYYEAIYKERWPGYLRELRQRYSASTVDVVEMMDDEKVNLIAALIRYIVLEE-EDGAILVFLPGWDNISTLHDLLMSQVMFKS-----DKFIIIPLHSLMPTVNQTQV-F-PGVRKIVIATNIAETSITIDDVVYVIDGGKIKETHFDTQNNISTMSA. 441
33 -11.6004q2c_A mol:protein length:949 CRISPR-associated helicase Cas3  ali model follow..  13  309...........................................................................................................................................................................TTVQAAALAGEVKSPSITIIEAPMGEGKTEAAMLLADTFSTAHSGCYFALPTMATSNQMFGRVTD--------------------YLRHRYPEDVVVVNLVHGHSDLSALLQELRQKGEEIFQLQGVYDEALGDEQLGAVVAGQWFTRGKRALL-------------------------------PPYGVGTVDQALLAVLQALSTKTVIVDEV-HAYDVYMTTLLHRSVPVVVLS--ATLPSARRRELVKAYARGA------GWQAERDLPPAGY---PRITYAAAEDVRGIHFAPSEASRRKVALRWVSAPEHEALGQLLAEAL-----------------SQGGCAAIICNTPRAQALYSALREVFPGLAEDGMPELDLLHARYPYEEREVREART-LGRFSRNGRRPHRAILVATQVIEQSLDLDFVTDLAPVDLVLQRMGR................................. 698
34 -11.5004s20_K mol:protein length:974 RNA polymerase-associated protein RapA  ali model follow..  153.........................................................................................................................................................................SLIPHQLNIAHDVGRRHAPVLLADEVGLGKTIEAGMILHQQLLSGERVLIIVPETLQ-VEMLRRFNLRFALFDDERYAEAQHD-------------------------------------------------------------------------------------------------AYNPFDTEQLVICSLDFARRSHLCEAEWDLLVVDEASREYQAIEQLAEHVPGVLLLTATPEQLDPNRFHDELNMLGEMIGEQDIEPLLQAANSDSQELVSMLMDRHGTSRVLFRNTRNGVKGFPKRELHTIKLPLPTQYQTAIKVSGIMGARKSAEDRARDMLYPEEGDNATWWNFDPRVEWLMGYLTSH-----RSQKVLVICAKAATALQLEQVLREREGIRAAAWFAEEDTGAQVLLCSEIGSEG-VMF--NPDLLEQRIGRLDR----IGQAHDILEKTAQSVLVRWYHEG...... 628
35 -11.4004ats_A mol:protein length:293 STRUCTURAL PROTEIN ORF273  ali model follow..  10  1......................................................................................................................................................................................MGSSSSGLVPRGSHMGEKITEEREFQSISEPEEEIDATNDEEKLADIVENEIEKEIRKSKTRKCKTIEN-LRDGKIYPASDYDIEVEKGKRSANDIYAFVETDVTRDFDEFLFDIDYGLPSISDILKFYLEKAGFRIANEVPTPNLKYYIHAVVEFGEDRPQ------YLAVNIYDIDSLARALRIPQIVEQKKPRTITADEFNDIERIV-EQPILAGAYLQLFPTPYQ---VCYEWKARWFNKIDCLKLERLKPSS................................................................................................................................................................................................................... 287
36 -11.4001z3i_X mol:protein length:644 similar to RAD54-like  ali model follow..  12  54........................................................................................................................................................................KVLRPHQREGVKFLWDC---CIMADEMGLGKTLQCITLIWTLLKQSDKVIVVSPSSL-VRNWYNEVGK--------------------------------------------------------------------------------LGGRVQPVAIDGGSKDEIDSKLVNFISQQGMRIPTPIL----IISYETFRLHAEVLHKGKVGLVICDEGSDNQTYLALNSMNAQRRVLISGTPIQVNSGILGTDASDKDRAAGEQKLQELISIVNRCLIR-RTSDILSKY-QKELYKLFLKQ--AKPVESLQTGKISVSSLSSITSLKKLCNHPALIYEKCLTDLFPQNYSTKAVEPQLSGKMLVLDYILAMTRTT--TSDKVVLVSNYTQTLDLFEKLCRRRYLYVRLDGTMSIKKRAKIVERFNNPSSPEFIFMLSSK-CGLNLIGANRLVMFDPDWNPANDEQAMARVWRDGQKKTCYI.. 521
37 -11.3003b85_A mol:protein length:208 Phosphate starvation-inducible protein  ali model follow..  18  9...........................................................................................................................................................................TLGQKHYVD-AIDTNTIVFGLGPAGSGKTYLAMAKAVQALQSKSRIILTRPAVEAGEKL---------------PGTLNEKIDPY--------------LRPLHDALRDMVEPEV---------------------------------------------------------------IPKLMEAGIVEVAPLAYMRGRTLND---AFVILDEAQNTTPAQMKMFLTRGSKMVVTGDITQVDLPGGQKSGLRLVRHILR............................................................................................................................................................................................................................ 179
38 -11.1004qqw_A mol:protein length:964 CRISPR-associated helicase, Cas3 family  ali model follow..  14  295........................................................................................................................................................................NGLQASLAKHLPCLCTGPGLVLITAPMGEGKTEAAYHVADLLGKATPGRFLALPTMATADQMHTRLKEYARYRVENTDLPRSSTLA-------------------------------------------------LHSMAWLNPDYAPADLPGVSKVLSNLGHRDPFAATDWLMGRKRGLLAPWAVGTIDQALMAVLRAKHNALRLFGLKVVVVDEA-HAVDPYMQVLLEQDVPVVL------LSATLHHSIANSLVKAYLEGARGRRWNRSEPQPVSEVSYPGWLHVDARIGKVTRSSDVDPLPIATTPRKPLEVRLVDVPVKEGALNRSTVLA------KELTPLVKQGGCAAIICTTVAEAQGVYDLLSQWGEDAPDLYLLHS-NRQRTEITATIVDLFGKEGAQSGRRPTRGAVLVATQVVEQSLDLDVISDLAPVSLLLQRAGR................................. 703
39 -11.1005o6b_A mol:protein length:545 ATP-dependent DNA helicase PIF1  ali model follow..  16  1.........................................................................................................................................................................GLSKEQESIIKLAENGHNI-FYTGSAGTGKSILLREMIKVLKGIRENVAVTASTGLAACNI------------------------GITIHSFAGIGLGKGDADKLYKKVRRSRKHLRRWENI--------------------------------------------------------------------------------------GALVVDEISM-LDAELLDKLDFGIQLIFCGDFFQLPP-VSKDPNRPTKFAFESKAWKEGVKMTIMLQKVFRQRGD------VKFIDNRMRLG-NIDDETEREFKKLSRPLPDDEIIPAELYSTRMEVERANNSRLSKLPGQVHIFNAIDGGALEDEELKERLLQNFLAPKELHL----GAQVMMVKN-----LDATLVNGSLGK-----VIEFMDPETYFCYEALTNDPSMPPEKLETWAEN............................... 336
40 -11.0005vhe_A mol:protein length:933 DEAH (Asp-Glu-Ala-His) box polypeptide 36  ali model follow..  11  127.............................................................................................................................................................................GMQKELVNMIDNHQVTVISGETGCGKTTQVTQFILDNYIERGKIVCTQPRRISAISVAERVAAERA--SCGNGNSTGYQIR---LQSRLPR------------------------------------------------------------------------------------------KQGSILYCT-TGIILQWLQSSSVSHIVLDEIHENLQSDVLMTVVK-----LLSYRPDLKVVLMS---ATLNAEKFSEYFGNCP----MIHIPGFTFPVVEYLLEDIIEKIRYVPEQKEHRSQFKKGFMQGHVNRQEKYYYEAIYKERWPGYLRELRQRYSASTVDVVEMMDDEKVNLIAALIRYIVLEE-EDGAILVFLPGWDNISTLHDLLMSQVMFKS-----DKFIIIPLHSLMPTVNQTQV-F-PGVRKIVIATNIAETSITIDDVVYVIDGGKIKETHFDTQNNISTMSA. 504
41 -11.0005wx1_A mol:protein length:733 Serine protease NS3  ali model follow..  13  250.............................................................................................................................................................................TEMVKKITTMNRGEFRQITLATGAGKTTELPRSVIEEIGRHKRVLVLIPLRAAAESVYQYMRQKHPSIAFN------GEMKEGDMATGITYASYGYFCQMPQPKLRAAMVE--------------------------------------------------------------------------------------------YSFIFLDEYHCATPEQLAIRFSENLRVVAM---TATPAGTVTTTGQKHPIEEFIAVEEMKSNMLVFVPTRNMAVETAKKLKAKGYNSGYYYSGEDPSNLRV-----------------VTSQSPYVVVAT------------------NAIESGVTLPDLDVVVDTGLKCEK--RIRLSSKMPFIVTGLKRMAVTIGEQAQRRGRDYHYDLLQAQRYGIEDGINITKSFREMNYDWSLYEEDSLMITQLEILNN.................... 618
42 -10.9005jpq_i mol:protein length:1073 Kre33  ali model follow..  13  257..........................................................................................................................................................................RTVDQAKALLTFVTLRNTVTLTAARGRGKSAAMGVAIAAAVAYGSNIFITSPSPENLKTLFEFVFKGFDALD-------------------YKDHADYTIIQSTNPEFNKAIVRVNIHRNHRQTIQ----------------------------------------------------------------------RPQDAHVLGQAELVVIDEAA-AIPLPLVKKLMGPYLVFMA-------STISGYEGTGLSLKLIKQLREQSRAGANPNGGNAVEVDRSTL--------KATKETTSVGGRSLKEITLSEPIRYAQGDNVEKWLNTLLCLDATLPRSKISTTGCPDPSQCELLHVNRDTLFSFHPVSEKFLQQMVALYSHYKNSPNDLQLMSDAPVIQVSLEGLSRGQQDLIPWLVSQQFQDDEFASLSGARIVRIATNPDYMSM--YGS-------KALQLLVDYYEGKFA.... 666
43 -10.9003h1t_A mol:protein length:590 Type I site-specific restriction-modification system, R (Restriction) subunit  ali model follow..  14  180...........................................................................................................................................................................RYYQQIAINRAVQSKKRSLITMATGTGKTVVAFQISWKLWSARPRILFLADRNVLVDDPKDKTFTPFG-------------------------------------------------------------------------------------------------------DARHKIEGGKVVKSREIYFAIYQSIASKEFPQDFFDLIIIDECHRGSARD----LEYFEPAFQIG----MTATPLREDNRDT-YRYFGNPI-----------YTYSLRQGIDDVISEVDAAGWRPSKGDVDRFGREIPDGEYQTKDFERVIALKARTDAFAKHLTDFMKRTDRFAKTIVFCVDQEHADEMRRALNNLNSDLSRKHPARVTSEEGKIGKGHLSRFQELETLTTSQLLTGVDKNVVLARVVNSMSKQIVG-----RGTRLREDYGKLWFNIIGSATQNFADPDFDG.............. 572
44 -10.9004a2w_A mol:protein length:936 RETINOIC ACID INDUCIBLE PROTEIN I  ali model follow..  11  248.........................................................................................................................................................................KARSYQIELAQPAINGKN-ALICAPTGSGKTFVSILICEHHFQRKAKVVFLATKVPVYEQQKNVFKHHFERQGYSVQGISGENFSNVSVEKVIEDSD--------------------------------------------------------------------------------------IVVTPQILVNSFEDGTLTSLSI--FTLMIFDECHNTTGNHPYNVLMTSQLPQILG----LTASVGVGNAKNIEETIEHICSLCSYLDIQAISTVRENIQELQRFMNK--LMRTIAYVDTLSQNSKKDFGTQNYEHWIVVEHLRKYNDALIISEDARIIDALSYLTEFFTNVKNNPKLEELVCILDDAYRYNPQTRTL-LFAKTRALVSALKKCMEEPSQKGVLDAFKSKDNRLLIATSVADE-----GI--DIVQCNLVVLRGRAAILVTSKTEVVENEKCNRYKEEMMNK....... 767
45 -10.8005gqh_A mol:protein length:1090 CRISPR-associated nuclease/helicase Cas3 subtype I-F/YPEST  ali model follow..  12  408............................................................................................................................................................................DCAMACREQAMEHGFFGLNLASTGCGKTLANGRILYALADPQRRFSIALGLRSLTLQTGQAYRERL-------------GLGDDDLAILVGGSAARELFEKQQERLER----------------------------SGSESAQELLAENSHVHFAGTLEDGPLREWLGRNSAGNRLLQAPILACTHLMPASESLRGGHQIAPL--SDLVLDEDFDIDDLPALSRLVHGSRVLLSS--ATLPPALVQGEAYRSGREIFQRHRGAPGRATEIRSSQSSAHGAVTSFSEAH---AKLEQLPPRRQAQLCTVHAAGEARPALCRELAGQMNTWM--DLHRCHHTEHQGRRISFGLLRLANIEPLIELAQAILAQGAPEGLHVHLCVYHSRHPLLRSAIERQLD-KALQASTERDHLFVVLASPVAEVGRDHDYIVEPSSMRSIIQLAGRNLYLLS........................... 877
46 -10.6003u44_B mol:protein length:1166 ATP-dependent helicase/deoxyribonuclease subunit B  ali model follow..  12  2..........................................................................................................................................................................................GAEFLVGRSGSGKTKLIINSIQDELRRGKPIIFLVPDQMTFLELAKTPMGGMIRAQVFSFSRLAWRVLQHTGGMSRPFLTSTGVQMLLRKLIEEHKQEFKVYQKASDAQVERMLTEFKRYCLEPEDIRRMAESGTASEYRGERVLSEKLHDLSILYQQMEKSLADQYLHSEDYLTLLAEHIPLA--EDIKGAHIYVDGPQEFRVLEQLMVHAEHITFSLTADKPSYEREPHELELFRMTGKTYYRLHQ------KAKELNLDITYKELSGTERHTKTPELAHLEA-------------------------------YEARPAIPYAEKQEALTVMQAANRAELEGIAREIHALVEKGYRYKDVAILA---RQPEDYKDMVKEVFADYEIPYFIDGKASMLLIEFIRS-----LDVLKGNWRYEAVFRCVKTELLFPLNEPKAKVREQVDQLENYCIAYGI.... 438
47 -10.5005tnu_A mol:protein length:459 DNA-dependent ATPase XPBII  ali model follow..  17  82.........................................................................................................................................................................ELRDYQAEAVK-AWLKEKRGIIVLPTGAGKTQVALKIVSIM---KVATLIVVPTIDLITQWKERINKDFDPGIIGGGED----------------------------------------------------------------------------------------------------------SLKGITVITYDSAYTRAELGNKFPLLIFDEVHHLPSEGYSIMAQLFASPYRLG----LTATPERDDGKHELYPILVGPIVYRKSVEELAGAKYKIKKLYVSLTNEE-YDGLRKKLKDFLSSRGLKLQNLDDFHR-------------LVKLAAKDKEAREALLAWHESLNIAVNSQSKIEKLREILQEYKNEKII-VFTRDTQMAYRISKTFLIPVVTYKTDK---DEREEILQKF----RDGEYRVIVASTVFDVDVPDATLAIVMGGYGTKRQFLQRLGRILRKKDKEALLIEI 437
48 -10.4003rvb_A mol:protein length:493 RNA helicase  ali model follow..  11  35.............................................................................................................................................................................TDNSSPPAVPQTFQVAHLHAPTGSGKST---KVPAAYAAQGYKVLVLNPSVAATLGFGVYMSKAHGIIRTGV---------------------------------------------------------------------------------------------------------RAITTGGPITYSTFLADGGCSGGA--YDIIICDEC-HSTDSTSILGIGTVLDQAETAGARLV--VLATATPPGSVTVPHPNIEEVALSNTGEIPFYKAIPIEVIRGGRHLIFCHSKKKCDELAAKLSALGLNAVAYYRGLDVSVIPTSGDVVVVAT------------------DALMTGYTGD-FDSVIDCNTCVTQT-----VDFSLDPTFTIDTTTVPQDAVSRSQGRGRRGIYRFVTPGERPSGM................................................... 335
49 -10.4005ivw_V mol:protein length:782 TFIIH basal transcription factor complex helicase XPB subunit  ali model follow..  14  315.........................................................................................................................................................................VLRPYQEKSLRKMFGNGR-GVIVLPCGAGKSLVGVTAACTV---RKRCLVLGNSAVSVEQWKAQFKMWSTI-QICRFTS-----------------------------------------------------------------------------------------------------AKDKPIGCSVAISTYSMLGHEWLKTQEWGLMILDEVHTIPAKMFRRVLTIVQAHCKLG----LTATLVRED--DKIVDLNFLI-----------PKLYEANWM------------ELQNNGYIAKVQCAEVWCPMSPEFYREYVA------------------IKTKKRILLYTMNPNKFRACQFLIKFHERRN---DKIIVFADNVFALKEYAIRLNKPYRMQILQNFKNPKINTIFISKVGDT-----SF--DLPEANVLIGGSRRQEA-LGRVLRAKKGMVAEEYNAFFYS....... 661
50 -10.2006bu9_A mol:protein length:1724 Dicer-2, isoform A  ali model follow..  10  11...........................................................................................................................................................................RGYQLRLVDHLTKSNGIVYL--PTGSGKTFVAILVLKRFSQDGKRALFMCNTVELARQQAMAVRRCTNF-----------KVGFYVGEQGVDD---------------------------------------------------------------------------------TRGMWSDEIKKNQVLVGTLDMVTQTYVALSSLSVVIIDECHHGTGHHPFREFMRTKLPRVVG----LTGVLIKGNEKELEITYRGNIITVSDTKEMENVMLYATKPEYGIYAASIAIISLIVEFDIKRRQAETLSVKLMHRTALTLCEKIRHLLVQKLQDMTYDDDDDNVNTEEVIMNFSTPKVQRFLMSLKVSFADKDPKDICCLVVERRYTCKCIYGLLLNKWQKSAIQQFRDGNANLMICSSVLEE-----GI--DVQACNHVFIRARTTVLFTADKEREKTIQQIYQY............. 523
51 -10.1004d2i_A mol:protein length:500 HERA  ali model follow..  10  20.....................................................................ERPVRLGTYVVL---EYDNVKALGLITNVTRGSPLLDDNMNDIEIVQRLKQFNNSIPVYTKAKVKLLCDMNNHFLMPDIPPFAGTPAREAEDEELKSIYSQIGSLIGKNVEVKLNINSFAAILAATGSGKSNTVAVLSQRISELGGSVLI-------FDYHGEYYDSDIKNLNRIEPKLNPLYMTPREFSTLLEIRENAIIQYRILRRAFIKVTNGIRAALAAGQIPFSTLNSQFYELMADALETQGNSDKKSSAKDEVLNKFEEFMDRYSNVIDLTSSDIIEKVKRGKVNVVSLTQLDEDSYLRRILDIAVIEEAENTLTKYWASRIAREGRLTIV---SQRPKGLDENILSQMTNKIILKIIEPTDKKYILESSDNLSEDLAEQLSS-------LDVGEAI.................................................................................................................................................................................. 446
52 -10.1002zjo_A mol:protein length:482 Genome polyprotein  ali model follow..  10  30.............................................................................................................................................................................TDNSSPPAVPQAFQVAHLHAPTGSGKST---KVPAAYAAQGYKVLVLNPSVAATLGFGAYMSKAHGVIRTGV---------------------------------------------------------------------------------------------------------RTITTGAPITYSTFLADGGCSGGA--YDIIMCDEC-HSTDSTTILGIGTVLDQAETAGARLV--VLATATPPGSVTVPHPNIEEIALSNTGEIPFYGKAIPIETIKGGRHLFCHSKKKCDELAAKLSALGIHAVAYYRGLDVSVIPASGNVVVVAT------------------DALMTGFTGD-FDSVIDCNTC-----VTQTVDFSLDPTFTIETTTMPQDAVSRSQSRGRRGIYRFVTPGERPSGM................................................... 330
53 -10.0002oca_A mol:protein length:510 ATP-dependent DNA helicase uvsW  ali model follow..  14  113.........................................................................................................................................................................EPHWYQKDAVFEGLVNRR-RILNLPTSAGRSLIQALLARYYLENEGKILIIVPTTALTTQMADDFVDYRLF-------------------------------------------------------------------------------------------HAMIKKIGGGASKDDKY------NDAPVVVGTWQTVVKQPKEWFQFGMMMNDECHLATGKSISSIISGLNNCFKFG----LSGSLRDGKANIMQYVGMFGEIFKPVTTSKLMEDGQVTELKINSIFLRYPDEFTTKLKGKTYQEEIKII------------------------------------------TGLSKRNKWIAKLAIKLAQKDENA----VMFKHVSHGKAIFDLIKNEDKVYYVSGEVDTETRNIMKTLAENGKGIIIGI--SVKNLHHVVVKSKIIVLTIGRVLRKHGSKTIATVWDLIDD....... 457
54 -9.9904wxp_A mol:protein length:451 NS3-4 protease  ali model follow..  11  6.............................................................................................................................................................................TDNSSPPAVPQSFQVAHLHAPTGSGKST---KVPAAYAAQGYKVLVLNPSVAATLGFGVYMSK-----AHGIDPNIRTGVRAITTGGPITYSTYGKFLADGGCSGGA------------------------------------------------------------------------------------------------YDIIICDEC-HSTDSTSILGIGTVLDQAETAGARLV--VLATATPPGSVTVSHPNIEEVALSNTGEIPFYKAIPIEVIRGGRHLIFCHSKKKCDELAAKLSALGLNAVAYYRGLDVSVIPTSGDVVVVAT------------------DALMTGYTGD-FDSVIDCNTCVTQT-----VDFSLDPTFTIDTTTVPQDAVSRSQGRGRRGIYRFVTPGERPSGM................................................... 306
55 -9.9606c90_A mol:protein length:734 Exosome RNA helicase MTR4,Exosome RNA helicase MTR4  ali model follow..  11  72.........................................................................................................................................................................ILDAFQREAIQCVDNNQSV-LVSAHTSAGKTVCAEYAIALALREKQRVIFTSPIKALSNQKYREMYEEFQDVGL------------MTGDVTINP-------------------------------------------------------------------------------------------TASCLVMTTEILRSMLYRGSEVAWVIFDEIHYMRDSETIILLPDNVHYVF------LSATIPNAR------QFAEWICHLHKQPCHVIYTDYRLQHYIFPAGGDGLHLVVDENGDFREDNFNTAMQVLRDAGDLAKGDQKGRKGPVIIFSFSKKDCEAYALQMTKLDFNTDEEKKMVEEVFSNLLKRGIGIHHGGLLPILKETIEILEGLIKALFATETFAMGINMPARTVLFTNARKFDGKDFRWISSGEYIQMSGRAGRRGMDDRGIVILMVDEK.................. 475
56 -9.8505d0u_A mol:protein length:714 Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP43  ali model follow..  13  42.............................................................................................................................................................................KQRQEFLDLYHNNQILVFVGETGSGKTTQIPQYVLYD-QTGKLIACTQPRRVAAMSVAQRVADELDV-EVGYSIRFENKTSSKTLLKYMTDGQ----------------------------------------------------------------------------------LLREAMHDRDM---------------SRYSCIILDEAHETLATDILMALLK-----LSERRKDLKIIVMS---ATLDAQKFQSYFFNAP----LLAVPGRTHPVEIFYAERDYVEAAIRTGEEEIEDACRRISLEVDEMIRESDAGPMSVYPLIFEKAPQPFRPGGRPGRKCIVATNIAETSLTIDGIVYVVDPGFSK-----QKIYNPRTR-VESLLVSPISKASAQQRAGRAGRTRPGKCFRLYTEEAF--YPEILRSNLSNTVLELKKLGVEDPETMMRALEELNYLACLDDDGELTPL 460
57 -9.7705mz4_A mol:protein length:752 Genome polyprotein,Genome polyprotein  ali model follow..  13  258.............................................................................................................................................................................TEMVKKITTMNRGEFRQITLATGAGKTTELPRSVIEEIGRHKRVLVLIPLRAAAESVYQYMRQKHPSIAFN------GEMKEGDMATGITYASYGYFCQMSQPKLRAAMVE--------------------------------------------------------------------------------------------YSFIFLDEYHCATPEQLAIRFSENLRVVAM---TATPAGTVTTTGQKHPIEEFIAVEEMKNNMLVFVPTRNMAVEAAKKLKAKGYNSGYYYSGEDPSNLRV-----------------VTSQSPYVVVAT------------------NAIESGVTLPDLDVVVDTGLKCEK--RIRLSPKMPFIVTGLKRMAVTIGEQAQRRGRDYHYDLLQAQRYGIEDGINITKSFREMNYDWSLYEEDSLMITQLEILNN.................... 626
58 -9.7304bpb_A mol:protein length:698 PROBABLE ATP-DEPENDENT RNA HELICASE DDX58  ali model follow..  15...........................................................................................................................................................................RNYQLELALPAMKGKN-TIICAPTGCGKTFVSLLICEHHLKQKGKVVFFANQIPVYEQNKSVFSKYFERHGYRVTGISGATAENVPVEQIVENND--------------------------------------------------------------------------------------IILTPQILVNNLKKGTIPSLSI--FTLMIFDECHNTSKQHPYNMIMFNYLDQKLGGSSGPLPQVIGLTASKTTDEALDYICKLCASDASVIATVKHNLEELEQVPQKFFRKVESRISDKFKYIIAQLMRDTESLAKRICKDLENLNDALIISEHARMKDALDYLKDFFSNVRAAGKLEDLCFILQEEYHLNPETITI-LFVKTRALVDALKNWIEGNPKLCILDAFKG-DHNILIATSVADE-----GI--DIAQCNLVILRGRARFLLTSNAGVIEKEQINMYKEKMMND....... 536
59 -9.6905ffj_A mol:protein length:1406 Endonuclease and methylase LlaGI  ali model follow..  12  3...............................................................................................................................................................PENVVVKKPKKLRDYQQTAKENAFKENDRGQLIMAPGTGKTFTSLKISEALSKDKNKVLYLVPSIQLLTQTLRGWNNDITSMAVTSDRDASRG--------------------------------------------------------TDGTEDIKASDIGYPATTSSKKILQNWHDFESLPKQTDMLVVFSTYQSIEVIGEAQKEGFPE------FDFIISDEAHRTT--GAHEAAKEASAFSKVHSNNNVK------GLKRMYQTATPKIYGESAKKNA------DKSILLSSMDDESKYG-RMGFGQAVSRDILTDYKVM-----------------VLAVDEAAIQKDMQRTLADPENGLNIDDVGRIVGIWNGMMRRNGYKRTIEESKKVSSQFEEVVNEYISHLSMRHADGKMNALQKGEILDWLADPPADEARIVSNVRFLTEGIDIPTLDAVIFLSPK--------KSQVDIVQAVGRIM.. 434
60 -9.6002wzq_A mol:protein length:619 NS3 PROTEASE-HELICASE  ali model follow..  11  173...........................................................................................................................................................................EGPDYEVDEDIFRKKRLTIMDLHPGAGKTKRIPSIVREALKRRLRTLILAPTRVVAAEMEEALRG-------------------------------------------------------------------------------------------------------LPIRYQTPAVKSDHTGREIVDLMCHATFTTRLLSSPNYNLIVMDEA-HFTDPCSVAARGYISTRVEMGEAAAIPGSTDPFPQSNSPIEDIEREIPERSWNTGFDWITDYQGKTVWFVPSIKAGN---DIANCLRKSGKRVIQLSRKTFDTEYPKTKLTDWDFVV--------------------TDISEMGANFR-AGRVIDPRRCLKPVILTDGPERVILA------GPIPVTPASAAQGRNPA-MLLDNIYQAIDGEFRLRGEQRKTFVELMRRGDLPVWLSKVASAGISYKDREWCFTGERNNQILE. 575
61 -9.5402fwr_A mol:protein length:472 DNA repair protein RAD25  ali model follow..  16  87.........................................................................................................................................................................SLRDYQEKALE-RWLVDKRGCIVLPTGSGKTHVAMAAINEL---STPTLIVVPTLALAEQWKERLGIEEYVGEFSGRIK----------------------------------------------------------------------------------------------------------ELKPLTVSTYDSAYVNAKLGNRFMLLIFDEVHHLPAESYVQIAQMSIAPFRLG----LTATFEREDGRHVGGKVFELFPDSLAGKHL---AKYTIKRIFVPLAEDERYEKREKVYKQFLRARGITLRRAEDFNK-------------IVMASGYDERAYEALRAWEEARRIAFNSKNKIRKLREILERHRKDKII-IFTRHNELVYRISKVFLREEREEILEGFRTGRFRAIVSSQVLDE-----GI--DVPDANVGVSGSAREYI-LGRILRPSKGKKEAVLYELISRGTGEVNT 454
62 -9.5405wdx_A mol:protein length:649 JFH-1 NS3  ali model follow..  12  203.............................................................................................................................................................................SDNSTPPAVPQTYQVGYLHAPTGSGKST---KVPVAYAAQGYKVLVLNPSVAATLGFGAYLSKAHGIIRTGVRTV---------------------------------------------------------------------------------------------------------MTGEAITYST---YGKFLADGGAYDIIICDEC-HAVDATSILGIGTVLDQAETAGVRLT--VLATATPPGSVTTPHPDIEEVGLGREGEIPFYGRAIPLSCIKGGRHLFCHSKKKCDELAAALRGMGLNAVAYYRGLDVSIIPAQGDVVVVAT------------------DALMTGYTGD-FDSVIDCNVAVTQA-----VDFSLDPTFTITTQTVPQDAVSRSQGRGRQGTYRYVSTGERASGM--LCECYDAGAAW...................................... 519
63 -9.4503pg5_A mol:protein length:361 Uncharacterized protein  ali model follow..  12  2.........................................................................................................................................................................................RTISFFNNKGGVGKTTLSTNVAHYFALQGKRVLYVPQCNATQ---------------MLTEEQTESIYLDGLNDEVAERNSLAKTVYAIFVPLREGESQIAAEITPMRSERFGVD-PGHPALSQIEDLMSDSWQSALGRQTGPFRRIHWAGQLAHAMERDDR-----------------------------YDVIFFD-----VGPSL----PFNRTVLLGCDAFVTPTDLFSFHAFGNLARWFDAWVTQYAEIHEGNMAEWKKYSADVEAKTRPLRLGGFDGEGLR-------------------------YLGYTTLEYVKRRANGQEQLVGAFERFRGRFAAEAERISNSLSKH-SNSTLLGHVPHMHSMPATAQDVHAPIMELSSSDRVRGAQINQR------NAYAEKINSVAANVYKALFPNELE.................................. 355
64 -9.4405sva_Z mol:protein length:843 DNA repair helicase RAD25  ali model follow..  13  361.........................................................................................................................................................................QIRPYQEKSLSKMFGNGR-GIIVLPCGAGKTLVGITAACTI---KKSVIVLCTSSVSVMQWRQQFLQWCTL-NCAVFTSDNKEMFQTESGLVVSTYSMVANTRNRSHDSQKVMDF---------------------------------------------------------------------------------------LTGREWGFIILDEVHVVPAAMFRRVVSTIAAHAKLG----LTATL--VREDDKIGDLNFLI-----------PKLYEANWM------------ELSQKGHIANVQCAEVWCPMTA------------------EFYQEYLRETARKRMLLYIMNPTKFQACQFLIQYHERRG---DKIIVFSDNVYALQEYALKMGKPFRMNILQNFQNDQINTIFLSKVGDT-----SI--DLPEATCLIYGSRRQEA-LGRILRAKRRN.................. 697
65 -9.4305vvr_M mol:protein length:1085 DNA repair and recombination protein RAD26  ali model follow..  13  296.........................................................................................................................................................................LLFNYQKTCVQWLYEL---GIIGDEMGLGKTIQVIAFIAALHHSGLPVLIVCPATVMKQ--FQHWWPPLRTVILHSMGSGMASDQKFKMDE--------------------------------------------------NDLENLIMNSKPSDFSYEDWKNSTRTKKALESSYHLDKLIDKVVTDGHILITTGLRIHSDKLLKVKWQYAVLDEGHKIRNPDSEI-LKTHNRIILSGTPIQIFPGKLGTNATNIQVQTGYKCAVALRDSPYLLR---RVKADVKDLPQKSKYLEFLHSSDLNQIQ-----NGKRNVLFGIDILRKICNHPDLL------DRDTKRHNPDYGDPKRSGKMQVVKQLLLLWHKQG---YKALLFTQSRQMLDILEEFISSHLNYLRMDG-NIKGRQSLV----RFNNESFDVFLLTTR-LGVNLTGANRIIIFIGQKREVS---IYRLMVGGSIEEKIY... 789
66 -9.3702f55_A mol:protein length:435 polyprotein  ali model follow..  11  3....................................................................................................................................................................................AVPQTFQVAHLHAPTGSGKST---KVPAAYAAQGYKVLVLNPSVAATLGFGAYMSK-----AHGIDPNIRTGVRTITTGGSITYSTYGKFLADGGCSGGA------------------------------------------------------------------------------------------------YDIIICDEC-HSTDSTTILGIGTVLDQAETAGARLV--VLATATPPGSVTVPHPNIEEIGLSNNGEIPFYGKAIPIEAIKGGRHLFCHSKKKCDELAAKLTGLGLNAVAYYRGLDVSVIPPIGDVVVVAT------------------DALMTGFTGD-FDSVIDCNTC-----VTQTVDFSLDPTFTIETTTVPQDAVSRSQGRGRSGIYRFVTPGERPSGM--LCECYDAGCAWYELT.................................. 316
67 -9.3506gpg_A mol:protein length:714 Probable ATP-dependent RNA helicase DDX58  ali model follow..  27...........................................................................................................................................................................RNYQLELALPAMKGKN-TIICAPTGFGKTFVSLLICEHHLKQKGKVVFFANQIPVYEQQKSVFSKYFERHGYRVTGISGATAENVPVEQIVENND--------------------------------------------------------------------------------------IILTPQILVNNLKKGTIPSLSI--FTLMIFDECHNTSKQHPYNMIMFNYLDQKLGGSSGPLPQVIGLTAS--TDEALDYICKLCASDASVIATVKHNLEELEQVVYKQWIVTVQKACMVFQMPDKDEESRICKALFLYTSHLRKYNDALIISEHARMKDALDYLKDFFSNVRAAGKLEDLCFILQEEYHLNPETITI-LFVKTRALVDALKNWIEGNPKLCILDAFKASDHNILIATSVADE-----GI--DIAQCNLVILRGRARFLLTSNAGVIEKEQINMYKEKMMND....... 546
68 -9.3405n8r_A mol:protein length:944 CG9323, isoform A  ali model follow..  12  157.............................................................................................................................................................................KYADDIIQAVRENQVILIVGSTGCGKTTQVPQILLDDAISRGCIICTQPRRISAIAIAEWVSYERC--SVGYQIRLESRKAR---------------------------------------------------------------------------------------------------ERASITYCT-TGVLLQQLQSHNLSVLILDEIHESVETDLLMGLLK-----ILPHRPDLKVILMS---ATVREQDFCDYFNNCP----MFRIEGVM------FPVKMLYLEDVLS--KTNYEFQKFRDRRPKRDPPERRMKHEAMIEPYLRRIRNSYDSRVLDKLRLPESEGCEDIDFIADLVYYICENE-PEGAILVFLPGYDKISQLYNILDKPKTSKGQR----WRDHMAVFSLMQSGEQQAV-F-AGQRKVIISTIIAETSVTIDDVVYVINSGRTKATNYDIETNIQSLDE. 526
69 -9.3101a1v_A mol:protein length:476 PROTEIN (NS3 PROTEIN)  ali model follow..  11  20.............................................................................................................................................................................TDNSSPPAVPQSFQVAHLHAPTGSGKST---KVPAAYAAQGYKVLVLNPSVAATLGFGAYMSK-----AHGVDPNIRTGVRTITTGSPITYSTYGKFLADGGCSGGA------------------------------------------------------------------------------------------------YDIIICDEC-HSTDATSILGIGTVLDQAETAGARLV--VLATATPPGSVTVPHPNIEEVALSTTGEIPFYKAIPLEVIKGGRHLIFCHSKKKCDELAAKLVALGINAVAYYRGLDVSVIPTSGDVVVVAT------------------DALMTGFTGD-FDSVIDCN-----TCVTQTVDFSLDPTFTIETTTLPQDAVSRTQGRGKPGIYRFVAPGERPSGM................................................... 320
70 -9.2906dcr_A mol:protein length:694 Primosomal protein N`  ali model follow..  12  30..............................................................FDYLLPEGMTVKAGCRVRVP---GKQQERIGIVVSVSDKAVVEVLDSEPVFTHSVWRLLLWAADYYHHPIGDVLFHAAANAPDIDLASETPEFSDWRTNYAVSGERLRLNTEQATAIHSAADTFSAWLLAGVTGSGKTEVYLSVLENVLAQGKQALVMVPEIGLTPQTIARFRE-----RFNAPVEV--------LHSGLNDSERLSAWLKAKNGEAAI-----------------------------------------------------------------------VIGTRSALFTPFKNLG----------VIVIDEEHDSSYKQQEGWRYHARDLAVYRAHSEQIPIILGSATPALETRLTRRAGNARPAIQHVLDLKGQKVQAGLAPALITRMRQHLQADNQV----------------------------ILFLNRRGFAPALLCHDCGWIAECPRCDHYYTLHQAQHHLRCH-GSTHLVPVGLGTEQLEQTLAPLFPGVPISRIDRVHRGGARILIGTQMLAKGHH-VALLDVDGALFSADFRSAERFAVAGRA......................... 541
71 -9.2505gvu_A mol:protein length:476 NS3 helicase  ali model follow..  13  1..............................................................................................................................................................................EMVKKITSMNRGDFKQITLATGAGKTTELPKAVIEEIGRHKRVLVLIPLRAAAESVYQYMRLKHPSISFN------GDMKEGDMATGITYASYGYFCQMPQPKLRAAMVE--------------------------------------------------------------------------------------------YSYIFLDEYHCATPEQ----------LAIIGKIHRFSESI--------------RVVAMTATPAGSVTTTGQKHPIEEFIAPEVMKGEDLGSQFLDIAGLKIPVDEMKGNMLVFVPTRNMAVEVAKKLKAKGYNSGYYYSGEDPANLRVVTSQSPYVIVATNAIESGVTLPDLDTVIDVSSKIPFIVTGL-KRMAVTVGEQAQGRVKHYDLLQAQRYGIEDGINVTKSFREMNYLLITQLEILNNLLISEDLPAHPEPIQLAYNSYEVQVPVLF 407
72 -9.2003b6e_A mol:protein length:216 Interferon-induced helicase C domain-containing protein 1  ali model follow..  15  33.........................................................................................................................................................................QLRPYQMEVAQPALEGKN-IIICLPTGSGKTRVAVYIAKDHLDKPGKVIVLVNKVLLVEQLFRKEFQPFLKKWYRVIGLSGDTQLKISFPEVVKSCD--------------------------------------------------------------------------------------IISTAQILENSLLNLEDAGVQLSDFSLIIIDECHHTNKEAVYNNIMRNNRLKKENKPVIPLPQILGLTAS.................................................................................................................................................................................................................................... 216
73 -9.2004ojq_A mol:protein length:464 Serine protease NS3  ali model follow..  11  13.............................................................................................................................................................................TDNSSPPAVPQSFQVAHLHAPTGSGKST---KVPAAYAAQGYKVLVLNPSVAATLGFGAYMSK-----AHGVDPNIRTGVRTITTGSPITYSTYGKFLADGGCSGGA------------------------------------------------------------------------------------------------YDIIICDEC-HSTDATSILGIGTVLDQAETAGARLV--VLATATPPGSVTVSHPNIEEVALSTTGEIPFYKAIPLEVIKGGRHLIFCHSKKKCDELAAKLVALGINAVAYYRGLDVSVIPTNGDVVVVST------------------DALMTGFTGD-FDSVIDCN-----TCVTQTVDFSLDPTFTIETTTLPQDAVSRTQGRGKPGIYRFVAPGERPSGM................................................... 313
74 -9.1705aor_A mol:protein length:1293 DOSAGE COMPENSATION REGULATOR  ali model follow..  12  388.............................................................................................................................................................................AMRSEILTAINDNPVVIIRGNTGCGKTTQIAQILDDYICSGQNIYVTQPRRISAISVAERVARERC--TVGYSVRFESVFPR---------------------------------------------------------------------------------------------------PYGAILFCT-VGVLLRKLEARGVSHIIVDEIHEDVNSDFLLVILR-----MVDTYPDLHVILMS---ATIDTTKFSKYFGICP----VLEVPGRA------FPVQQFFLEDIIQMTDFVPSAESRRKRKEVEDEEQLLSEDKDEAEINYNKVCEDKYSQKTRNAMAMLSESDVSFELLEALLMHIKSKN-IPGAILVFLPGWNLIFALMKFLQNTNIFGDTSQYQ-----LPCHSQIPRDEQRKV-F-EGVTKIILSTNIAETSITIDDIVFVIDICKARMKLFTSHNNLTSYAT. 754
75 -9.1601wp9_A mol:protein length:494 ATP-dependent RNA helicase, putative  ali model follow..  11  11...........................................................................................................................................................................RIYQEVIYAKCKETNCLIVL--PTGLGKTLIAMMIAEYRLTKGGKVLMLAPTKPLVLQHAESFRRLFNL---------------------------------------------------------------------------------------------PPEKIVALTGEKSPEERSKAWARAKVIVATENDLLAGRISLEDVSLIVFDEAHRAVGNYAYVFIARAKNPLVIGNSPDVRPYVKGIRFEWVRVDLPEIYKEVRKLLREMLRLKPLAETGLLESSSPDIPKKEVLRAGQIINEEMAKGNHDLRGLLLYHAMALKLHHAIELLETQG-EEAKAGSTKASKEIFSDKRMKKAISLLVQAKEIGLDHPKM-VFTNYRETAKKIVNELVKREQKLILDEFARGEFNVLVATSV-----GEEGL--DVPEVDLVVGRHMPGRVII----LMAKGTRDEAYYWSSRQKEKIMQ. 493

FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Li W, Wooley JC, Godzik A. Probing metagenomics by rapid cluster analysis of very large datasets. PLoS ONE. 2008;3(10):e3375. Epub 2008 Oct 10.