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Query: TM0005 TM0005 281886 Purified-2001-01-30, from T.maritima

Results of FFAS03 search in PfamA32U
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MTVQQFIKKLVRLVELERNAEINAMLDEMKRLSGEEREKKGRAVLGLTGKFIGEELGYFLVRFGRRKKIDTEIGVGDLVLISKGNPLKSDYTGTVVEKGERFITVAVDRLPSWKLKNVRIDLFASDITFRRQIENLMTLSSEGKKALEFLLGKRKPEESFEEEFTPFDEGLNESQREAVSLALGSSDFFLIHGPFGTGKTRTLVEYIRQEVARGKKILVTAESNLAVDNLVERLWGKVSLVRIGHPSRVSSHLKESTLAHQIETSSEYEKVKKMKEELAKLIKKRDSFTKPSPQWRRGLSDKKILEYAEKNWSARGVSKEKIKEMAEWIKLNSQIQDIRDLIERKEEIIASRIVREAQVVLSTNSSAALEILSGIVFDVVVVDEASQATIPSILIPISKGKKFVLAGDHKQLPPTILSEDAKDLSRTLFEELITRYPEKSSLLDTQYRMNELLMEFPSEEFYDGKLKAAEKVRNITLFDLGVEIPNFGKFWDVVLSPKNVLVFIDTKNRSDRFERQRKDSPSRENPLEAQIVKEVVEKLLSMGVKEDWIGIITPYDDQVNLIRELIEAKVEVHSVDGFQGREKEVIIISFVRSNKNGEIGFLEDLRRLNVSLTRAKRKLIATGDSSTLSVHPTYRRFVEFVKKKGTYVIFLast
1 -71.000PF13086.6; B6HQI4_PENRW/1305-1589; AAA domain  ali follow..  30  1.........................................................................................................................................................................SINRAQARAIKSAVDNDAFTLIQGPPGSGKTKTITALVGSLLSDSKKLLLCAPSNAAVDELVMRLKDGVSVLRLGRSDAINTKVLDVTLEEMVNARLNQDPSKGNGVDLQKLYEEHKTTDTSFKELRARLDEKGLPPPEELEREFDLMKKKRSQLSTSIDKARDQNHTLARNADMHKRRIQEQIINESHVICTTLSGSGHEIFQNVEFETVIIDEAAQCIELSALIPLKYGSKCVLVGDPKQLPPTVLSK....................................................................................................................................................................................................................................... 285
2 -70.800PF13087.6; DNA2_RAT/805-1017; AAA domain  ali follow..  33  1.......................................................................................................................................................................................................................................................................................................................................................................................................................................MSESLFKRLER-NESAVVQLTIQYRMNRKIMSLSNKLTYEGKLECGSDRVANAVITLPNLKDVRLEFYADYSDPDNPVCFLNTDKVP---APEQIENGGVSNVTEARLIVFLTSTFIKAGCSPSDIGIIAPYRQQLRTITDLLARSVEVNTVDKYQGRDKSLILVSFVRSNEDGTLGLLKDWRRLNVAITRAKHKLILLGSVS........................ 213
3 -35.600PF01443.18; RDRP_TMV/829-1085; Viral (Superfamily 1) RNA helicase  ali follow..  14  1............................................................................................................................................................................................VLVDGVPGCGKTKEILSRV-----NFDEDLILVPGKQAAEMIRRRANSS----------------------------------------------------------------------------------------------------------------GIIVATKDNVKTVDSFMMNFGKSTRCQFKRLFIDEGLML-CVNFLVAMSLCEIAYVYGDTQQIPYINRVSGFPYPAHFAKLEVDE-----VETRRTTLRCPADVTHYLNRRYEGFVMSTSSVKKSVSQEMVGGA------------------------------------------------------AVINPISKPLHGKILTFTQSDKEALLSR--GYSDVHTVHEVQGETYSDVSL--VRLTPTPVSIIAGDSPHVLVALSRHTCSLKYY............................ 256
4 -17.800PF13245.6; B1YJE6_EXIS2/332-475; AAA domain  ali follow..  21  1..............................................................................................................................................................................QREAIELAVKAP-LMVLTGGPGTGKTTVIKGILHALQEEVYPYVLVAPTGRAAKRLSEATDVPAMTIH-------------------------------------------------------------------------------------------------------------------RLLKYDGTNFQLDEDQPIAGKVLIIDESSMILLSSLLRAVPNGMKILFVGDRDQLPSV........................................................................................................................................................................................................................................... 142
5 -17.100PF13604.6; Q3L956_RHOE4/579-769; AAA domain  ali follow..  21  1.........................................................................................................................................................................ALGNDQIAMIEHFLTAKTVAVAVGAAGAGKTTAAKVVARAWEQTNGKVIALGPSAKAADVLGAEI-----------------DVEGRTIADILTRDQHGLATG---------------------------------------------------------------------------------IEKGDLL--------------------LVDEAGMARNLADLTRIASGAVVRLLGDPLQLASV----ESGGVLRDLAERT------DAPFLSKIHRFKTVGEAAASLQLRDGDESA...................................................................................................................................................................................... 176
6 -16.500PF09848.9; A1A222_BIFAA/236-699; Uncharacterized conserved protein (DUF2075 topsan)  ali follow..  10  1.........................................................................................................................................................................................SRLIFVQGVAGTGKTVLLSHLFYRIATEMDINGRINDEDDEDILETDS--------------SLKISKEDRRKAYILVNHNQQMHVYNQIASKLGLQKHFGEVALKPSQFINRFSEKTTSNRAIADKPRG------------------------------------------------------------KADVVLVDEAHLLLTQGDQ--LRRAKVVIAVFDPNQITAAGYSGQLERFVPLNMWG--DHYLLSRICLHRQFRIADATIRWIDDFADGKRIGRIPQDIGEK-----------DRKTGEYVREPFEIRVFDSPVGKAIKEKAYLKASGVDGCGLSRVVATYDWEYKGGKINDSSPYFCHPWNYEIKVGDKGLSLD-EVGSTFSIQGFDLNYVIIG--NGSISYAQSNLRNELN--VLLKRGVHGLYL............................. 460
7 -12.700PF07652.14; Q32ZD8_9FLAV/1675-1822; Flavivirus DEAD domain  ali follow..  20  1......................................................................................................................................................................................FKKKQLIVLDPHPGAGKTRKVLEFIRQAVERRLWTLALAPTRVVAAEMAEALNG-------------------------------------------------------------------------------------------------------LPVRYLTPAVIQQHTGKEIVDLMCHATFTMRLLSGPNYNMFIMDEA-HFTDPSSIAARGYISTKVDMGEASAV---FMTATPPGSREP............................................................................................................................................................................................................................... 142
8 -12.200PF02399.15; OBP_VZVD/13-828; Origin of replication binding protein  ali follow..  11  29......................................................................................................................................................................LELQLDVPVKLIKPGMSQTRPVTVVRAPMGSGKTTALLEWLQHALKADISVLVVSCRRSFTQTLIQRF-----------------------------------------------------------------------------------------------------NDAGLSGFVTYLTSETYIMGFKRLIVQLESLHRVSSEAIDSYDVLILDEVMSVIG--------------------------LYSPTMRRLSAVDSLLYRLLNRCSQIIAMDATVNSQFIDL-------SGLRGDENIH------------TIVCTYAGVGFSGRTCTILRDMGIDTLVRVIKRSPEHEDVRTIHQLRGTFFDELALRLQCGHNICIFSSTLSFSELVAQFCAIFTD-PLCNVNEWKHFRVLVYTTV------TVG-------LSFDMAHFHSMFAYIKPMSYGPDMVSVYQSLGRVRL....... 357
9 -11.500PF00580.21; REP_HAEIN/3-266; UvrD/REP helicase N-terminal domain  ali follow..  14  1..........................................................................................................................................................................LNPQQQQAVEYV--TGPCLVLAG-AGSGKTRVIINKIAHLIEKCKQIAAVTFTNKAAREMKERVAH------IGKEQSKGLLVSTFTLGFDILKREYKALGFKSNMTLFDEHDQFALLKELTADVLKEDKDLLRELISVISNWKNDLISPKQAFALARDAKYQTFAKCYERYATQIRTYNALDFDDLIMLPTLLFKQNEEVRSQAKIRYLLVDEYQDTNTSQYELIKLLVACFTVVGDDDQ---SIYSWRGARPENMVLRD........................................................................................................................................................................................................................... 261
10 -10.000PF02562.16; A0LK93_SYNFM/124-328; PhoH-like protein  ali follow..  17  6...........................................................................................................................................................................SVKQKEYIE-AIRHYDIVFGVGPAGTGKTYLAMAMAVAAMTKDRRIVLVRPAVEAGEKL---------------PGDLAEKVNPY--------------LRPLYDALHDMMDFER---------------------------------------------------------------ATGLLQRGAIEVAPLAFMRGRTLND---AFVILDEAQNTTTEQMKMFLTRGSKAVITGDITQIDLPENKPSGLIEAIDLLQGI.......................................................................................................................................................................................................................... 178
11 -9.630PF05127.14; A2EVG1_TRIVA/302-494; Helicase  ali follow..  13  2..............................................................................................................................................................................................ITAARGRGKSAAIGLSLAAALALGSNIFVTAPSIANLTALFEFVIVGLTALGFREGESEDFEV---------------------------------------------------------------------------------VKSNPTSSKERPYVTRVNVHLSHGRRQTVQYVRPNMTQYLGQCEILAIDEAA-AIPLPIVRQLMGPYTTLFS-------STVDGYEGTGLSLKLFKEFQRTMKSRFTQTTIRYAEGDPIEAWLHNLL............................................................................................................................................................................................. 190
12 -9.100PF05872.12; Q2YMR9_BRUA2/13-501; Bacterial protein of unknown function (DUF853 topsan)  ali follow..  10  2...........................................................................................................................................................................KPDDTYQQPEYLALQYGGLVTGATGTGKTVSLQVLAESFSAAGVPVFCADIKGATISEMGPLLLS-----RLMNLTDAQEGVLNIAFRLADEEGLLLLDLKDLQAILTEMAGRSDELSAKYGNVNK-----ASVGAIQRSLLVLDQQGGSKFFGEPALRIADLMRTTTDGRGVVSVLAADKLMMNPRLYSTFLLWLMSELFEELP--VFFFDEAAPKALIDRVEQVVRLIRIYFV---TQNPLDVPETVLAQLGNRVQHALRAYTPRETNAVKTAADTFRPNPDFNTFQAIT-SLGTGEAL------------------VSTLQAKGVPSMVQRTLMRPPSSRIGPLTPEERAQIIAASPVAGQYDQPLDRDSAFEMLA--QQKTGQEEEGGGGLLGDIIGTALGTGRRSGRQTVAEAAMKS--VRSVG-----SSLGRALVRG-----ILGG.......................... 488
13 -9.000PF07693.14; Q87KS6_VIBPA/37-380; KAP family P-loop domain  ali follow..  13  2........................................................................................................................................................................GKYAKFLHNYLVDNSSQRGYVLLNAQWGAGKTYFINRWIDSIKDAHPVVYIDAWKQDYSDDPMLTVV-----------SSIIDALEEHLPAGNKKAIALKNKATRFFKAAAPLLMKGLIKKATGMNIDDVEPETEKKEGSDLYNLTGEASAALAKCLDDHNEKLKTVEHLRSDIKSLIEALDPKKKLKLPAF-------------------IFIDELDRC-RPSYAVEMLEVIKFVVATDTEQLQHAVKAVYGEGFDQTYLGRFFR........................................................................................................................................................................................................................ 248

FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Doctor KS, Reed JC, Godzik A., Bourne PE. The apoptosis database. Cell Death Differ. 2003 Jun;10(6):621-33. Review.