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Query: TM0013 TM0013 281894 Purified-2001-08-24, from T.maritima

Results of FFAS03 search in PfamA32U
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MFENEILFDNGQHKFMFLGWEEKEEEIVQTNQYLILDGNEGILLDPGGAHVFPRVMSNVAEVVDLSSIRHIFYTHQDPDVTSGILLWLSICENAKIYISSLWVRFLPHFGIYDQKRIVPISDKGTKIKLLSGNELEILPAHFLHSTGNFVLYDPVAKILFSGDIGAAVFEKGKRYRYVDDFERHLPLMEAFHKRYMSSNAACKKWVDMVSKKKIDMIAPQHGAVFRGESVKKFLEWFRNLKCGVDLIDNLYSLLast
1 -31.900PF14597.6; K9Q9I8_9NOSO/1-199; Metallo-beta-lactamase superfamily  ali follow..  11  15.....................FNPARNIDFNGIAWIRPDGNILIDPVALSN-----HDWNHLESLGGVDWIILTN--SEHIRAAKEIAVQT-YAKVAGPAAEKECF--------PIACDRWLSDGDEFVSG---LTTIELQGSKTPGELALLLE-ETTLITGDLV---------------RAHKAGTLTILAKEKLLDPQAAIASVHRLAQLNVETVLVGDGWSVFRDGHLRLKELAATL............. 199
2 -25.700PF00753.27; PDLA_RHILO/30-244; Metallo-beta-lactamase superfamily  ali follow..  14  4...........................FPVYSILIEHAEGRFLIDTGYDYDHQTIPGALGLLLEPRDIDVVVNSHFHFDHCGGNKYF----PHAKKICHRSEVPQACNPQPFEHLGYSDLSFSDGDVDLARG--VKLISTP-GHSIGHYSLLVEFPRILFTIDAA----------------YTQKSLETLCQAAFHIDPVAGVNSMRKVKKLAED...................................... 214
3 -18.700PF14234.6; K8GHV6_9CYAN/48-368; Domain of unknown function (DUF4336 topsan)  ali follow..  10  18...........................VPIRMTIVKLAAGGLLV--APVAPTAECLQLVNELVE-GEVKYIILTVSGLEHKVFVGPFARYFPTAQVFIAPGQWSFPLNLSWLGFPIERTQILPEYSCNAPFGDEFEYAILGPIDLGAEVALYHPRSRTLLVTDSIVSVPDNPPEIIQLDPYAKDSAFDRVENTAENRRKGWHRMTLFAFFFRPSALEPVKTWQSIRDAFKAPDRSKRA............... 240
4 -15.900PF12706.7; I3ZD26_TERRK/61-263; Beta-lactamase superfamily domain  ali follow..  14  1.......................................RNLLVDP-ERLVLLRRQRPGILIDHLPPVDAVLLTHAHMDHLNLPSLRKRHATKLTVIVPKGVADLVENLGFRS-----VTELEWWQTTALADEPVSITMTPARHWGAGYVIAGAGHSVYHSGDTAYFGHEIGQRLQPQI---ALLPIGAYFPDSYRAVHTSPEEALQAFLDLGATTMVPMH................................ 186
5 -15.700PF16661.5; G0VCW5_NAUCC/19-212; Metallo-beta-lactamase superfamily domain  ali follow..  11  1.................................ILKFDNVTILIDPGWTSTEVSYVDCVKYWNLIPEIDVILISQPTIECLGAYTLLYENFLRIAVYATLPVANLGREDIEAAFDHIQILKYSQMIDLRSKFDGLTFFALNSGVNPGGSIISTYSEKLVYAPRW......................................................................................... 163
6 -12.600PF13483.6; B9JRY8_AGRVS/77-244; Beta-lactamase superfamily domain  ali follow..  8  5...........................LGHSTFEIETPQGLTIDTDYSGYLRSAR-----------TPDVVTMNKAHSSHYT-----LSPDPGIAQVLHGWNDA--------------QPGEPVHHNLVVGDAYIRNVATDIRSWGGDFIFEVAGLCIGHLGHL--------HHELTDKQFAAIGRLDVVMVPVDGGLTLGSDSMSRMVKRLRSALILPMH................................ 168
7 -10.300PF17030.5; I3EIZ1_NEMP3/1-217; Putative beta-lactamase-like family  ali follow..  12  10........................HNGTTQDGYLMESHETSLLFDPPSKVLDSDVELCGISDRGPPDITGIFITNSNSLSVFFVES------DVTIYLTDYIYLQMKSISEYKEISRRVKIIRHNQVINFTYLSITAQAA--GLSLGWIMYQDKEKICAYAYGI......................................................................................... 180
8 -10.000PF02112.15; Q5AGE4_CANAL/35-421; cAMP phosphodiesterases class-II  ali follow..  8  45..............................CETVSYYYHPNVTITTPFSNFQPGRPILHTQNI--NNLQNYLISHSHLDHVCSVAGFNKNMSNKILYGSHYTINAMQQHNMPSFKIVNLNYLESNRSERIGIYTVKMFDLS--HGEFNKLTEDKEDAQHHSNSN......................................................................................... 187
9 -7.330PF16285.5; Q81VH8_BACAN/8-251; Domain of unknown function (DUF4931 topsan)  ali follow..  5  43..............................NKFTLKDTFQTVLIETDNRSLIRFSVKHWLDLQKNEEFKSVILYKNHGPFSGGS-----HHAHMQIIGMKYVNYLDN---------VEQDNFQGVIVQKNKNIELNISDRPIIGFTEFNIIVKDIECIDEMANYIQQTVRY---------LTDFHKGCSSYNLFFYHVSGKII--CKVVPRFVVSPLYVGYKIPQVSTKLEDVKIQLAEY............. 243
10 -6.830PF09740.9; UVSSA_RAT/507-613; Uncharacterized conserved protein (DUF2043 topsan)  ali follow..  10  2..........................................................................................................................................RAPMVPFGVDLCYWGQEQLTA-SQHRFWKPHEVEEEVDSAHVSEMLHSRHITFSGKFEPVQHKCRALRPRLCERQDRLKCPFHGKIIPRDDKGQPLN.................. 106
FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Grynberg M, Topczewski J, Godzik A., Paszewski A. The Aspergillus nidulans cysA gene encodes a novel type of serine O-acetyltransferase which is homologous to homoserine O-acetyltransferases. Microbiology. 2000 Oct;146 ( Pt 10):2695-703.