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Query: TM0018 TM0018 281899 Purified-2001-08-24, from T.maritima

Results of FFAS03 search in PfamA32U
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MPVNIKQLAQEFDKKEIGITQGHRLCPGCGAPITVKFVMMIARHLGYEPVVGLATGCLEVSTSIYPYTAWSVPYIHNAFENVAATMSGVETAYKALKNKGKIPEDKKYAFIAFGGDGGTYDIGLQSLSGMLERGHKVLYVLYDNEGYMNTGNQRSGSTPPGSDTTTAPVGKKLPGKVQLKKNIVEIVAAHENVYAATASLSEPMDFFAKVEKALNFDGPSFLAVFSPCVRFWRVNDDKTVEISKLAVETKYWPLYEVERGVYRVTRKPRQFKPVEEFLKAQGRFRKLLSRPDAKEIVDELQEYVDRRWERLLTLEEVTKDKPIRLast
1 -17.300PF02775.21; Q6LZH8_METMP/393-541; Thiamine pyrophosphate enzyme, C-terminal TPP binding domain  ali follow..  16  1.....................................................DVGQNQMWMAHY--KSFLSSGGQGTMGFGFPAAIGAKFA------------RPDANVIAVTGDGG-FLMNSQELATIAEYEIPVIVVIFDNRTLGMVY----------QWQNLYYGKRQCAVHLGETPDFLKLAESYG---IGALRVEKPEDINEAFKTALNSGKPYLLDI.................................................................................................... 149
2 -12.500PF13292.6; DXS_HELMI/5-280; 1-deoxy-D-xylulose-5-phosphate synthase  ali follow..  14  12.RLSATELDQLAKEIREVIIQTTSKNGGLGVVELTLALHLVFQSPKDKIIWDVGHQSYVHKLLTGRYNHFHTVFNTGHSSTSISAALGFAFARDLKKE--------DGAVIAVIGDGALTGIALEALNHAGHAGNDMIVVLNDNEKSIADN-YLSRIRTDPRYFRNKEEVEKMKDSFKHLVVPGILFEELGFSYLGPIDGHNLSQLREVMTNACRLKGPILVHVLT.................................................................................................. 276
3 -9.570PF00676.20; ODBA_BACSU/20-321; Dehydrogenase E1 component  ali follow..  15  103...........................................................................SSPVTTQVPHAVGIALAGRMEKK--------DIAAFVTFGEGSS-NQG-EGANFAAVHKLPVIFMCENNK-YAISVPYDKQVACENISDRAIGYG--MPGVTVNGNDPLEVYQA----------------VKEARERARRGEGPTLIETISYRLTPHSSDDDDSSYRGREEVEE----------------KKSDPLLTYQAYLKETGLLS--------DEIEQTMLDEIMAIVNEATDEAENAPYAAPE 302
4 -7.250PF01058.22; Q31DZ5_HYDCU/551-699; NADH ubiquinone oxidoreductase, 20 Kd subunit  ali follow..  1.........................CTGNSEAFIIDELILKFISLDYHELLMAASGPHSLDQLIEEDQGDYILIVEGAVPLGMGGNFLRIGPQGETGEALLKRVAQHASAVMAVGSCAFDG-GVVAAAPNPTGAVGVSEALGRDDIINLPGCPVNPINVVGTLLHY.............................................................................................................................................................. 149
5 -6.980PF06057.11; Q8PB04_XANCP/266-453; Bacterial virulence protein (VirJ)  ali follow..  15  1..........................................................................................................DTFAIFVSGDGGWAGLDEEVADALVAQG--IPVVGLDSLRYFWSERTPQGF------ATDLDRIARFYAQRWQRRRVVLIGFSQGADVLPAAINKLPAPTKQNLRMTA.............................................................................................................. 100
6 -6.840PF00456.21; TKT_HAEIN/3-334; Transketolase, thiamine diphosphate binding domain  ali follow..  11  60........................LSNGHGSMLIYSLLHLTGYDLSIEDLKQFRQLHSKTPGHPEYGYAPGVETTTGPLGQGITNAVGMAIAEKTLAGQFNREGHEDHHTYVFLGDGCLMEISHEACSLAGTLGLGKLIAFYDDNNISIDGHVDGWFSD----------------------DTAERFEAYGWQVIRNVDGHDAEQIRAATILAQAEKGPTLIICKT-------IGFGSPNKSGSHDSHGAPLGDEEIDLTRKALGWEYAPFEIPAEYYAESAKEKGAAAEKSWEEKFAAYAKAYPELAAEFKRRVS........ 328
7 -6.540PF17034.5; YAG1_SCHPO/778-905; Zinc-ribbon like family  ali follow..  13  72...KPQNYVKEVNLQKSRFGLWFSFCLNCGHGAHASHASEWFSTHTICPV----PNCD.......................................................................................................................................................................................................................................................................... 122
8 -6.380PF04606.12; E0SAM4_DICD3/25-71; Ogr/Delta-like zinc finger  ali follow..  13  2.........................CPECGSKAVIRKTNRKHRQIADIYCACADVECGYTFVMNLTFS................................................................................................................................................................................................................................................................ 44
9 -6.250PF04216.12; B4EFM8_BURCJ/22-308; Protein involved in formate dehydrogenase formation  ali follow..  15  147LQVAWTDLASRVTPTDVPYLDQPGLCPVCGTHPVASVVRVGGQYQGYRFLQCG---CTTEWH----------------MVRTKCSHCD---------------STKGIAYHGIEGGSEAIKAESKTYRKIGYQEDDLASLTLD--LMNEAGYQRSSPNPLL................................................................................................................................................................... 286
10 -6.110PF00148.19; Q20XD3_RHOPB/20-446; Nitrogenase component 1 type Oxidoreductase  ali follow..  11  1.........................CQPAGAQFASIGIKDCI------GIVHGGQGCVMFVRLLISQHLKESFEIASSSVHEDGAVFG-DRVETAVDVLLMRYPHVKVVPIITTCSTEVIGDDVDGLITKLEEGREVHLLAIHSPSFVVSGYDVAVRDFVKKFAKKGEPSGRINTGWVNPGDVKELKHLVSELGIEANVLFEIESFDSPLGAGISHGNTTVLEATGSAIHTFALNRYEGGKAAQLLEKKFKIPSTIGP---------PIGIRNTDALLK---KLSQVTGKPIPASLVKERGIALDAISDVAHMFLADKK..... 296

FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Bossy-Wetzel E, Barsoum MJ, Godzik A., Schwarzenbacher R, Lipton SA. Mitochondrial fission in apoptosis, neurodegeneration and aging. Curr Opin Cell Biol. 2003 Dec;15(6):706-16. Review.