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Query: [L] COG1039 Ribonuclease HIII, from VFDB

Results of FFAS03 search in COG1018
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MNIVLKLETKERQQLAEKYKSYEQVSKNPYITFFAKVGKTSISVYTSGKVVFQGNEAEKLASDFGHIAQVVPQKQTNLIGTDEVGNGSYFGGLMVTASFVSEENLNFLKEIGVADSKKLTDEKICQIAPKLIDRIPHVALVVEPAKYNEVIASGYNAVSIKVALHNQAIYLLEKQLGHKPENIVIDAFTTEANYKKYVNKEQNHPLTKVTLLTKAEDQFLAVAVSSIISRYLFLENLKKLSKESGFTLPSGAGNLSDKIAAQIIKSQGVDALNQLAKLHFANTQKAIKIAQLLast
1 -108.000[L] COG1039 Ribonuclease HIII  ali follow..  100  1MNIVLKLETKERQQLAEKYKSYEQVSKNPYITFFAKVGKTSISVYTSGKVVFQGNEAEKLASDFGHIAQVVPQKQTNLIGTDEVGNGSYFGGLMVTASFVSEENLNFLKEIGVADSKKLTDEKICQIAPKLIDRIPHVALVVEPAKYNEVIASGYNAVSIKVALHNQAIYLLEKQLGHKPENIVIDAFTTEANYKKYVNKEQNHPLTKVTLLTKAEDQFLAVAVSSIISRYLFLENLKKLSKESGFTLPSGAGNLSDKIAAQIIKSQGVDALNQLAKLHFANTQKAIKIAQL 292
2 -61.900[L] KOG2299 Ribonuclease HI  ali follow..  18  2........................................................SLKCETERSKTWNNFGNGIPCVLGIDEAGRGPVLGPMVYAAAISPLDQNVELKNLGVDDSKALNEAKREEIFNKMNEDIAYALRCLSPELISCSMLKRQKYS-LNEVSHEAAITLIRDALNVNVVEIKVDTVGPKATYQAKLEKL--FPGISICVTEKADSLFPIVSAASIAAKVTRDSRLRNWQFREKPDAGYGSGYPGDPNTKKFLQLSPVFGFCSLVRSSWKTASTIVEKRCV 248
3 -55.400[L] COG0164 Ribonuclease HII  ali follow..  16  2..................................................................SETFIYPQANLIAGVDEVGRGPLVGAVVTAAVILDPNRPIV----GLADSKKLSEKRRLSLYDEITEKASWSLGRAEPEEIDQL-----NILHATMLAMQRAVSGL----HIVPDYVLIDGNRCPK------------LQMPSLAVVKGDSRVAEISAASILAKVTRDREMTELFPEYGFAQHKGYPT---AFHLEKLAALGATVHH---RRSFGPVKRVLGL... 197
4 -6.940[S] COG2410 Uncharacterized conserved protein  ali follow..  8  2.............................................................................YCGIDVGLKKCHAALISDRLEFVGELDLDNVRVTGIDAPLSFPAKGSLRECERLLLKMGIRLFPSGAPFFRGIALRGMEIAEELRSKGVEVYEVYPYAT----VILNIAPKAKKHTKSGLEEIRAELSRWVEIPELSHDEVDAVIAA--LTVKLFSEGMGVKLEGIDGS.............................................. 168
5 -5.490[L] COG0389 Nucleotidyltransferase/DNA polymerase involved in DNA repair  ali follow..  10  8.......................................................DMDCFFAAVEMRDNPALRDIPIAIGGSRERRG-----VISTANY-------PARKFGVRSAMPTGMALKL--------------LTLLPGRFDAYKE------------ASNHIREIFSRYTSRIEPLSLDEAYLDVTDSVHCHGSATLIAQEIRQTIFNETASAGVAPVKFLAKIASDAEVPAFLQTLPLAKIPGVG----KVSAAKLEAMGLRTCGDVQKCDLVMLLKRFGK... 217
6 -5.320[H] COG0321 Lipoate-protein ligase B  ali follow..  14  15........................................EIWLVEHYPVFTQGQAGK--------AEHILMPGDIPVVQSDRGGQVTYHGPQVMYVLLLEQTVVNTLAEIGIEAHPRVGEKKICSLGLRIRRGCSFHGLALN-LRINPCGYAGMEMAKITQWKEDATTDNIAPRLLANILALL............................................................................................................ 181
7 -5.270[U] KOG0077 Vesicle coat complex COPII, GTPase subunit SAR1  ali follow..  11  25.............................................................................FLGLDNAGKTTLLHMLKDERLVQHQPTQHTSEELSIGKIK--GHQIARRVWKDYYAKVDAVVYLVDAYDKERFAESKRELDALLSDEALATVPFLILGNKIDIPYAA-----SEDELRYHLGLTNFTTGKGKVTLGDSGVRPLEVFMCSIVRKMGYGEGFKWLSQYIN............................................... 193
8 -5.220[R] COG3596 Predicted GTPase  ali follow..  11  43.............................................................................IMGKTGAGKSSLCNALLRFRLQIGEHFMTIVDLPGVGESGVRDTEYAALYREQLPRL----ILWLIKADDRALATDEHFYRQVIGEAYRHKMLFVISQ---------SDKAEPTSGGNILSTEQKQNISRKICLLHELFQPVHPVCAVSVRLQWGLRVMAERMIKCL................................................ 216
9 -5.150[S] COG4121 Uncharacterized conserved protein  ali follow..  14  1MFIMSSISHAQLG------DAGTPVSDQFDDVYFSNVNGLA----ETRYVFLEQNHLPQRWHNDDQRR----------FVIAETGFGTGLNFLAVWQAFVPDAKLKELHFISF-EKYPLSKSDLIQAHQAWPELAQFAQKLHKPLAIPECQRIVLNDGLVTLDLWKDCLPKVATQEQGLVDAWFLDGFAPSKNPEMWNQNLFA----GMAKLAKHGCTCATFTSAGFVRRGL---------IDAGFAMKKVKGFGTKREMIA.............................. 242
10 -5.060[DL] KOG1434 Meiotic recombination protein Dmc1  ali follow..  14  54LCKIKGLSEVKVEKIKEAAGKIIQVGFIPATVQLDIRQRLSTGSKQLDSILGGGIMTMSITE---------------VFGEFRCGKTQMSHTLCVTTQLPREMGGGEGKVAYIDTEGTFRPERIKQIAEGYELDPESCLANVSYARALNSEHQMELVEQLGEELSSGDYRLI-----------VVDSIMA-CGRGELSERQQKLNQHLFKLNRLAEEFNVAVFLTNQVQS.............................................................. 265
FFAS is supported by the NIH grant R01-GM087218-01
1 4 7 5 9 7   jobs submitted since Jan 1, 2011
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Alonso A, Rahmouni S, Williams S, van Stipdonk M, Jaroszewski L, Godzik A, Abraham RT, Schoenberger SP, Mustelin T. Tyrosine phosphorylation of VHR phosphatase by ZAP-70. Nat Immunol. 2003 Jan;4(1):44-8. Epub 2002 Nov 25.