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Query: [K] COG1522 Transcriptional regulators, from VFDB

Results of FFAS03 search in COG1018
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MSKVELDKIDRKILEVLQSNGRLTNLEVAERVNLSPSPCLRRIRRLEESGVIRQYAALLDPGKIGLGLSAYINVRLEKQGGAPKGKAPSDIFRAAVATWPEVVTCYAMTGEMDYLLKVFVEDMDHFARFIRDQLLAHPAVIDVKSSFALERIKDTTALPVVVLast
1 -86.600[K] COG1522 Transcriptional regulators  ali follow..  100  1MSKVELDKIDRKILEVLQSNGRLTNLEVAERVNLSPSPCLRRIRRLEESGVIRQYAALLDPGKIGLGLSAYINVRLEKQGGAPKGKAPSDIFRAAVATWPEVVTCYAMTGEMDYLLKVFVEDMDHFARFIRDQLLAHPAVIDVKSSFALERIKDTTALPVVV 162
2 -16.600[K] COG3355 Predicted transcriptional regulator  ali follow..  20  20AFMYGLSKSDVEVLHILLQNGKMTTDDLSQKLNVTKASISKALNNLLDKGLIQREKAPAEKEE................................................................................................... 82
3 -14.000[S] COG4344 Uncharacterized protein conserved in archaea  ali follow..  9  8IDELINDYDMLRVLKHFTIAHVDYAKNITRYTEIPQMRVREYLKRLKDLGLLDY............................................................................................................ 61
4 -13.700[K] COG1654 Biotin operon repressor  ali follow..  16  1...MKDTTVPLTLISLLADGEFHSGEQLGERLGMSRAAINKHIQTLRDWGV............................................................................................................... 48
5 -13.600[K] COG1846 Transcriptional regulators  ali follow..  16  35GRAGALTPSEIHTIDAIGTDEGLLMKELAERLGVTKGAVSQLVDRLEAKALVRRTAHPKVSRGIQVVLT--MHAAFYEELQQSFTKEEIAIFEQCVSKLRDILS.......................................................... 148
6 -13.300[K] COG2345 Predicted transcriptional regulator  ali follow..  25  15......GDTRRKILLILLERAPVIASDIAEQLQLSTVGVRRHLDNLVEENLAE............................................................................................................. 61
7 -12.900[S] COG3388 Uncharacterized protein conserved in archaea  ali follow..  13  12.NDMDTLKRHISVINVLLREQPIGIIKLSQETGIPEHKIRYSLRILEQENIIS............................................................................................................. 63
8 -12.700[K] COG4190 Predicted transcriptional regulator  ali follow..  18  67.....LTPRVLELIEAIRQEEPASINETARVVDRDVKNVHEELSRLAHLGIIF............................................................................................................. 114
9 -12.700[KH] COG1339 Transcriptional regulator of a riboflavin/FAD biosynthetic operon  ali follow..  26  1.....MKMKTLFLLIKLAKMGTVTMRELSRELDVSPQTVLRWLEELKEQGYIHK............................................................................................................ 55
10 -12.500[S] COG4519 Uncharacterized protein conserved in bacteria  ali follow..  11  1MELSPVFARRLYLALLVESLERPNVPKLIEKTGWPRRTIQDVIKAMPGIGIE.............................................................................................................. 52
11 -12.300[K] COG5625 Predicted transcription regulator containing HTH domain  ali follow..  13  14LKAIGLKKNEIRIRLLVEKRRGMRIREIQRELGISERSVRTHVLNLYRRGLLK............................................................................................................. 67
12 -12.300[K] COG1777 Predicted transcriptional regulators  ali follow..  23  14......NSTRREIIRMLTQFERSYALELSRSIGLSQQAILKQLEMLERANLVT............................................................................................................. 60
13 -11.600[K] COG4738 Predicted transcriptional regulator  ali follow..  9  29LRRLNINRPVALTLACLSKGDEISSQRIEMVSGLRQPEVSIAMRYLRENEWVDMREEKKNHGK-GRPVKLYKLTVQMETIIDTIEENVIAESKTILQNIERLKS.......................................................... 131
14 -10.900[J] COG4901 Ribosomal protein S25  ali follow..  23  47......EKVFQAIAKEVQNMRVITPYEIASKYGIKMSVAFKVLRNLKERGDLV............................................................................................................. 93
15 -10.600[K] COG1497 Predicted transcriptional regulator  ali follow..  12  9......ELTRFQILSEIMRQPYVRQKDIADKLGVTVQAVSENIKSLIAEGLVE............................................................................................................. 56
16 -10.300[S] COG2512 Uncharacterized membrane-associated protein/domain  ali follow..  19  245....PLSPELCEVLDIIGHKGRITQKDLRSKLDYSEVKVSLMLSELEKRGLIRKL-------RNGRE------LVLVDEEH................................................................................. 311
17 -9.610[S] COG3398 Uncharacterized protein conserved in archaea  ali follow..  23  185......NATNQRIISEIQNGKCNTNLALAREIGVSRATISWYVKNLKETGLID............................................................................................................. 231
18 -9.430[K] COG4742 Predicted transcriptional regulator  ali follow..  21  6IDVVFRSQKRRDLLLLLG-EEPRTMEDIKVLLDVSPTAILPQIKRLTDSNLVIQKNGSYELTDMG................................................................................................. 69
19 -9.400[K] COG1802 Transcriptional regulators  ali follow..  13  13LRYQVENVLRQAIMSRFTPGERLIERELCETLGVSRTSIREALRRLEAEKLVS-IVAIISRQEA-FALRGLLEGFAAREFAQRATDVAIVHFAQAIQALRMAGM.......................................................... 125
20 -9.040[J] KOG1767 40S ribosomal protein S25  ali follow..  30  50...........KLLTEAPKFKLITPSILSDRMRINGSLARRAIRELMAKGVIR............................................................................................................. 91
21 -9.020[K] COG1510 Predicted transcriptional regulators  ali follow..  12  24MHTFGMPSTVGRVLGII-NRKPMTLSELSEATGMSKTRMSQVVREMIDANIAEK............................................................................................................ 78
FFAS is supported by the NIH grant R01-GM087218-01
1 4 6 8 2 5   jobs submitted since Jan 1, 2011
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Luz JG, Hassig CA, Pickle C, Godzik A., Meyer BJ, Wilson IA. XOL-1, primary determinant of sexual fate in C. elegans, is a GHMP kinase family member and a structural prototype for a class of developmental regulators. Genes Dev. 2003 Apr 15;17(8):977-90. Epub 2003 Apr 02.