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Query: [S] COG5501 Predicted secreted protein, from VFDB

Results of FFAS03 search in COG1018
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MKLILALIPVTLTASLALAEPEKPNNPLADGTTWRDLKGDVVGEAAILDGSALFSVTAPYRANDAATVPVTIEQTDAAADPIESLKLVIDENPAPVAAEIRFGPAMAPLKFETRVRVNQYSNIRAIAETPRGIFMHGRFVKASGGCSAPATKDPVAALKDMGEMRLKLFGGKGEVQKARREAQIMIRHPNYSGLQRDQITQLFVSAKFITELVVKQGDELLFALDGGISISENPVFRFSYTDNGAPDFTVHAVDTDGNVFDRVLPKTPPALast
1 -111.000[S] COG5501 Predicted secreted protein  ali follow..  100  1MKLILALIPVTLTASLALAEPEKPNNPLADGTTWRDLKGDVVGEAAILDGSALFSVTAPYRANDAATVPVTIEQTDAAADPIESLKLVIDENPAPVAAEIRFGPAMAPLKFETRVRVNQYSNIRAIAETPRGIFMHGRFVKASGGCSAPATKDPVAALKDMGEMRLKLFGGKGEVQKARREAQIMIRHPNYSGLQRDQITQLFVSAKFITELVVKQGDELLFALDGGISISENPVFRFSYTDNGAPDFTVHAVDTDGNVFDRVLPKTPPA 270
2 -11.600[C] COG2033 Desulfoferrodoxin  ali follow..  12...........................................................................................................................................SLVHHKAKVIGMLKETIRSGDWKGEK-HVPVIEYEREGDLVKVEVSVPHPNT-------------PEHHIAWIELYFHPEGGQFPILHSDPLTEPRAVFFFKTSKKGKLYALSYCNIHGLWENEVQLE... 137
3 -6.280[Q] COG2132 Putative multicopper oxidases  ali follow..  4WTRRGLLKTAAVAGATGVGLSAIGRLGGLAATSPEPMVLQTAKIQARLMDIGP-AGMPPVLMKKGEPFAARLVNAIDDPTTIHGIRLPNKMDGVPFLVQPYVNTGD---HFDYAFTPPDAPHCNTLEQMGHGLT----------GVIVVENPNDPKFDAEFGQFIDQFRPRDAAKTGTYGTVRTA------NWLQYDAPAGGLVRLRVAITYAFRVDGAEAIVMALDGNPVPERF-ALLLGPGQRMELAIRMPDREGAVV.......... 283
4 -6.250[S] COG5608 Conserved secreted protein  ali follow..  10  1MGKVGAIIGIIFLSWLLYSAYFVMNFSPTVRGEWGPM------------EGNNVEIIFHVDLGNPSPIPVAVQ----------SLNLSLAGVEI-EQAKIGIFERSTNVVAVVNLDKIAEALVNHIKDKENSIAEINANIKVLG--EPRVYSLGMIPFKTPGIEGIYARWGKVSTKEIELVGTIKLYNPNSFPIPVTNL-----------KADMYMNNIKIGEGRTLKGTI--------LQPNSRGTVDVALTFDVEKLKEAFKEHIRNG 254
5 -6.050[R] COG2373 Large extracellular alpha-helical protein  ali follow..  861.....................................................LALETPAKMRPNQPLTVKIKASTKNGEKPKNVLVSAVDSGVLNITDYVTPDPWQAFFGQKRYGADIYDIYGQVIEGQGR----LAALRFGGDGDELKRGGKPPVN----HVNIVVQQALPVTLNEQGEGSVTLPIGDFNG---------------LRVMAQAWTADDFGSNESKVIVAAPPRF---MASGDTSRLTLDITNLTDKPQKLNVALTASG 1061
6 -5.870[O] KOG0714 Molecular chaperone (DnaJ superfamily)  ali follow..  176..............................SKKMKISRDVLDSSGRPTPVEEILTIEIKPGWKKGTKITFLEKGNEHRGVIPSDLVFIVDEKPHPVFK-----------------RDGNDLVVMQKISLVDALTGYTAQVTTLDGRTLTVPVNNVISPSYEEVVKGEMPIPKDPSRKGNLRIRFIIKFPSKLTTEQKSGIKRMLSP................................................................ 335
7 -5.860[M] COG5581 Predicted glycosyltransferase  ali follow..  36......................................HGQFISKILAVDPEKLIVDYGSQEYENSAVLVEFTLPQLVTGEYQRLPAFITPLPSSLWFV--------QRREYFRIGAPLYPPYYGVTTLPDTRTLRFRLFDLSLGGMGALLESAIPDGLIEGARFSQVE---NMGQWGIFHVDAQLISISERKVIDGKNETITTPRLSFRFLNVSPAVERELQ............................................... 225
8 -5.590[P] COG0715 ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components  ali follow..  8FSRRKFIFTAGASASAVFLKGCLGNPPETTGGTQSAPTAQPAANVSAEQAPEVTTVKLGYIP-ESAPLIIAKEKGFFAKYGLTNVELSKQASWGSARDNVEQMPMPHLITEGLITKGNQKIPMYVLCQLIHGNGIAIANKHQGSGIGLRLASAKSLFSKLKASPTPFTAAQTFPAVNQDFWIRYWLA---AGGIDPDAD---------VKLLTVPSAQANMKTGTMDAFSTGDPWPF-RIVKDKVGFMAALTAE................ 265
9 -5.530[M] COG3133 Outer membrane lipoprotein  ali follow..  1MIKRVLAVSLMGLSLAGCVNNDSLSGDVYTASEAKQVQNVTYG---TIVNVRPVQIQGGDDSNVIGAI--GFLGNTIGGGTGRSLATAAGAVAGGVAGQGVQSAMNKTQGVELEIRKDDGNTIMVVQKQGNTRFSAGQRVVLASNG............................................................................................................................ 147
10 -5.310[S] COG3126 Uncharacterized protein conserved in bacteria  ali follow..  12  6PKALWQIVGGAALAVSLTGCAHQSAEAPVAAPISTATVAASVAQSTV---HGTVNIRERVALPPDAVVTVTLSLADAPSRVIAQKAVRTEGKQAPFTYSLPFNPS--------DIQPNARVIVSAAITRNGQLFITDTIQEVINRG............................................................................................................................ 144

FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Lesley SA, Kuhn P, Godzik A., Deacon AM, Mathews I, Kreusch A, Spraggon G, Klock HE, McMullan D, Shin T, Vincent J, Robb A, Brinen LS, Miller MD, McPhillips TM, Miller MA, Scheibe D, Canaves JM, Guda C, Jaroszewski L, Selby TL, Elsliger MA, Wooley J, Taylor SS, Hodgson KO, Wilson IA, Schultz PG, Stevens RC. Structural genomics of the Thermotoga maritima proteome implemented in a high-throughput structure determination pipeline. Proc Natl Acad Sci U S A. 2002 Sep 3;99(18):11664-9. Epub 2002 Aug 22.