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Query: [DL] KOG3999 Checkpoint 9-1-1 complex, HUS1 component, from VFDB

Results of FFAS03 search in COG1018
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MRFKTRISNLYTLTRLVQALDKIGRFCWLRLMPETVNFVIVPDFRMTQVWSVLEVETIFEDYVVQSNADNVINLEVPIDNFYKALRSAANASDSTVRLSKKNNQPLLSLSTTWSGRAFGSNIVTHNIPVRVLSQSYVSVIKEPTAPEPDCHIFLPQLNFLRHVVDKYKSLSDRIIMSANMSGELQLSVNIPSARVSTKWKGLENPELDPSQVEDISRHPSQTRAPEEFVHMRLDSKDLVNMLKISSVAKRVIACFCEGHALVLYVYITDPEDEHTAVLTYYISTYVDLast
1 -110.000[DL] KOG3999 Checkpoint 9-1-1 complex, HUS1 component  ali follow..  100  1MRFKTRISNLYTLTRLVQALDKIGRFCWLRLMPETVNFVIVPDFRMTQVWSVLEVETIFEDYVVQSNADNVINLEVPIDNFYKALRSAANASDSTVRLSKKNNQPLLSLSTTWSGRAFGSNIVTHNIPVRVLSQSYVSVIKEPTAPEPDCHIFLPQLNFLRHVVDKYKSLSDRIIMSANMSGELQLSVNIPSARVSTKWKGLENPELDPSQVEDISRHPSQTRAPEEFVHMRLDSKDLVNMLKISSVAKRVIACFCEGHALVLYVYITDPEDEHTAVLTYYISTYVD 287
2 -49.900[L] KOG1636 DNA polymerase delta processivity factor (proliferating cell nuclear antigen)  ali follow..  11  2..LELRLVQGSLLKKVLESIKDLVNDANFDCSSTGFSLQAMDSSHVALVSLLLRSE-GFEHYRC----DRNLSMGMNLGNMSKMLKCAGNDDIITIKADDGGDTVTFMFESPTQDKIADFEMKLMDIDSEHLGIPDAE----------YHSIVRMPSNEFSRICKDLSSIGDTVVISVTKE-GVKFSTAGDIGTANIVLR---------QNTTVDKPEDAIVIEMKEPVSLSFALRYMNSFTKATPLSDTVTISLSSELPVVVEYKVAE-----MGYIRYYLAPKIE 256
3 -37.400[DL] KOG3194 Checkpoint 9-1-1 complex, RAD1 component  ali follow..  7  2..FQAETVCLKQIQSTLRCID-FSKECTIEITSRGLRFAVEE-SQSLQAHAFLDKSLFQTFNFQGDSDGDTYMFQTMISPLLQSLSIYTDGKERISTSAWDQPTVNIICKVQYNGPGCPFIWEVEETACELLTMECEDDVDINRLASTLCTKIIMKSNWLYDALVELDNNMGENLI-SSQKSTFLLRCVGALSTTEIEYPN--------------EKSVLESFETDSENTYSYRFSLIRHALKALQVGSKVNLRIDENGTLSIQIML-VGQEGLCTFVDFCIVPLDL 282
4 -27.500[DL] KOG2810 Checkpoint 9-1-1 complex, RAD9 component  ali follow..  11  1MKYTLEGSNARVIAKAVQSLSKVGKEMFIEIDQQSLQMRAINATQSAVGSISFKRS-MFEVYDMPP--HSDFYCKISMKGCLAVFRNMNEVEYCELNLLDNQTNLQVNLRCKLETTKEAT-----------ISIIDDQNINTNINTDQMPNIIRGDHKLLTDISNNFNSSEEELTLEANS----------GSVVAKNYIEGARVNDKFMRTQLKLKPSEFEQYQVTKETVITFCIKEFRAFLLAECLNASLTLEFDEGMPFLLKI-----KKHGEIECLLIMSTLSP 260
5 -5.260[S] COG1710 Uncharacterized protein conserved in archaea  ali follow..  14  43VRILDNAPNVKVIGCPPSLYPKVSKKVLRALEQMGIKVIPVEKGRGRPRKYSYKTLMMIEELLKKGKTPREISLGIPIRTLYYLLKKREVSE................................................................................................................................................................................................... 136
6 -4.690[M] COG5581 Predicted glycosyltransferase  ali follow..  8  9.....LKKNPLAILGVLRDLNKNQVPLRISWAHGQFI-------------------------KILAVDPEKLIVDYGSQE--YENSAVLRAGQVAIIAETQGAKVEFTLPQLVTGEYQRLPAFITPLPLWFVQRREYFRIGAPLYPPYYGVTTLPDTRTLRFRLFDLSLGGMGALLESAIPDGLIEGARFSQVELNM.......................................................................................... 176
7 -4.630[R] COG3607 Predicted lactoylglutathione lyase  ali follow..  7  1MRMIFVNLPVKNIEVSKSFFTALGFSFNPEYSDDRTLCMIVEENIFVMLLQEDRFRDFINGDIADAKQSTEVLTCLSAEEIDEMIATALASGGSSWK.............................................................................................................................................................................................. 100
8 -4.360[R] COG0220 Predicted S-adenosylmethionine-dependent methyltransferase  ali follow..  12  1MRVRNRKGAGEMLAENAHIVVENPADFKGRWSE------RFGNDHPIHIEVGCGKGAFITGMAALHPEINYIAIDMQLSVLSYALDKAIEADLPNVQMMLVDGAALSEYFADGE---------IDQVYL---------NFSDPWPKGRHEKRRLTYKSFLATYEKILR-----------PEGEIHFKTDNR................................................................................................ 156
9 -4.360[L] COG0592 DNA polymerase sliding clamp subunit (PCNA homolog)  ali follow..  6  136.....TMLQRTSFAVSREESRYVLTGVLLAIANGVATIVGTDGKRLAKIDAEVTLDK-----------SFSGEYIIPIKAVEEIIKMCSDEGEAAIFLDQDK------IAVECDNTLLITKLLSGEFP-------------SPVISTESNVKLDLHREELITLLKQVALFTN------ESSHSVKFSFLPGELTLTA-----------NCTKVGEGKVSMAVNYSGELLEIAFNPFFFLDILKHSKDELVSLGISDSYNPGII--------TDSASGLFVIMPMRLH 364
10 -4.150[S] COG1931 Uncharacterized protein conserved in archaea  ali follow..  8  8VEVEAYVYPTEDINKVKKAMLNLVPGLKFEAFDKGLVGKTRDKRALQRLYELFRGQQILDMMLEEGYFGEEIIIKVHKQVAYANFNEESPLGPITITIRTKEPQKLM.................................................................................................................................................................................... 124
FFAS is supported by the NIH grant R01-GM087218-01
1 4 7 7 1 8   jobs submitted since Jan 1, 2011
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Bossy-Wetzel E, Barsoum MJ, Godzik A., Schwarzenbacher R, Lipton SA. Mitochondrial fission in apoptosis, neurodegeneration and aging. Curr Opin Cell Biol. 2003 Dec;15(6):706-16. Review.