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Query: [S] COG2512 Uncharacterized membrane-associated protein/domain, from VFDB

Results of FFAS03 search in CSGID
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MDLLMEMNLRFYIICIAALLTLLASASLALGVPFLEDNNVTATVHGATYAKDTLELLNDTVISINSTPSQSMVAKDGIYSFELAPGDYAITARYYRNNTLIYSKETTFKIEGEGNYVFDLLLYPVSEYPVTEPIQDSYSIDPPETIGIGPSTTDYLPISYLSIVFVLILLLGGGYKFSSKHKNTNKNKFQERKFDIPGILVKVPGRSTGLGVRSESSGGAVSLTEPIIEPAGNPDIETAALNRIPLSPELCEVLDIIRGHKGRITQKDLRSKLDYSEVKVSLMLSELEKRGLIRKLRNGRENILVLVDEEHLast
1 -14.900IDP00626 gene: sarT; staphylococcal accessory regulator T SACOL2506 [Staphylococcus aureus subsp. aureus COL]  ali follow..  22  32.....................................................................................................................................................................................................................................................LTLDNYLVLAYLKNDEGKYFMRDIISYIGIDQSRIVKSVKDLSKKGYLNKCR--RNVIIVVSVKQH 103
2 -14.500IDP00827 gene: sarU; staphylococcal accessory regulator U SACOL2507 [Staphylococcus aureus subsp. aureus COL]  ali follow..  21  32.....................................................................................................................................................................................................................................................LSLKELLILAYFYKNEHSISLKEIIGDILYKQSDVVKNIKSLSKKGFINKSR--RRIFVSVTPIQR 101
3 -14.500IDP00098 gene: slyA; transcriptional regulator NT01SF2011 [Shigella flexneri 2a str. 2457T]  ali follow..  19  31.....................................................................................................................................................................................................................................................LTQTHWVTLHNIHQLPPDQSQIQLAKAIGIEQPSLVRTLDQLEEKGLISRQT--RAKRIKLTEKAE 99
4 -14.300IDP00871 gene: slyA; transcriptional regulator SlyA STM1444 [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]  ali follow..  19  29.....................................................................................................................................................................................................................................................LTQTHWVTLHNIHQLPPDQSQIQLAKAIGIEQPSLVRTLDQLEDKGLISRQT--RAKRIKLTEKAD 97
5 -12.900IDP00642 gene: sarZ; staphylococcal accessory protein Z SACOL2384 [Staphylococcus aureus subsp. aureus COL]  ali follow..  19  36.....................................................................................................................................................................................................................................................LTYTGYIVLMAIENDEK-LNIKKLGERVFLDSGTLTPLLKKLEKKDYVVRTR--RNLQISLTEQGK 103
6 -12.700IDP90424 predicted OMP [Chlamydia trachomatis D/UW-3/CX] CT_546 [Chlamydia trachomatis D/UW-3/CX]  ali follow..  14  135....................................................................................................................................................................................................................................................KAGKQDVQLMQVLAGMGGSASREVLSQALSMRNVRADRVIRACQKKKLIFTHDNLIYSHFQQPQ... 198
7 -12.300IDP91319 transcriptional regulator [Vibrio vulnificus CMCP6] VV2_0325 [Vibrio vulnificus CMCP6]  ali follow..  22  50.....................................................................................................................................................................................................................................................LKMGEFDVVATLRRSGARLTPSELLGSLMLTSGAMTNRLDKLEQKGLISRQH-RRSVTVELTEHGL 120
8 -12.300IDP93833 DNA-binding transcriptional repressor ArsR [Yersinia enterocolitica subsp. enterocolitica 8081] YP_001007538 [Yersinia enterocolitica subsp. enterocolitica 8081]  ali follow..  25  10...................................................................................................................................................................................................................................................KNLSDETRGIVLLLKEM-GELCVCDLCTALDESQPKISRHLAMLRESGLLLDRKQGKWVHYRLSPH.. 75
9 -12.200IDP00724 gene: arsR; arsenical resistance operon repressor SACOL1822 [Staphylococcus aureus subsp. aureus COL]  ali follow..  21  2..........................................................................................................................................................................................................................................TYKELATFLKVLSDSSREILDLLSC--GELCACDLLAHFQFSQPTLSYHMKALVKTNLVTTRKIGNKHLYQLNHN.. 75
10 -12.100IDP02193 arsenical restistance operon repressor [Francisella tularensis subsp. tularensis SCHU S4] FTT0868c [Francisella tularensis subsp. tularensis SCHU S4]  ali follow..  17  2..........................................................................................................................................................................................................................................KLANIVDFQKALGDETRRILMVIYQ--HQLCLCHLAHIFKLANSTLSKHLDILRRNGFIHKRKQGRFHYFYFNSA.. 75
11 -10.700IDP00125 gene: lrp; leucine-responsive transcriptional regulator NT01ST1183 [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]  ali follow..  15  2...........................................................................................................................................................................................................................................VDSKKRPGKDLDRIDRNILNEL-QKDGRISNVELSKRVGLSPTPCLERVRRLERQGFIQGYYLDAS--ITLNRGAP 87
12 -10.700IDP00094 gene: lrp; regulator for leucine (or lrp) regulon and high-affinity branched-chain amino acid transport system NT01SF0993 [Shigella flexneri 2a str. 2457T]  ali follow..  15  2...........................................................................................................................................................................................................................................VDSKKRPGKDLDRIDRNILNEL-QKDGRISNVELSKRVGLSPTPCLERVRRLERQGFIQGYYLDAS--ITLNRGAP 87
13 -10.600IDP92553 gene: fadR; fatty acid metabolism transcriptional regulator FadR [Vibrio vulnificus CMCP6] VV1_2233 [Vibrio vulnificus CMCP6]  ali follow..  10  13.........................................................................................................................................................................................................................................................EKYIIESIWNGGSILAERELSELIGVTRTTLREVLQRLARDGWLT-IQHGKPTKV....... 71
14 -10.400IDP01032 gene: yhgG; putative cytoplasmic protein STM3507 [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]  ali follow..  20  5..........................................................................................................................................................................................................................................................IQVRDLLALR-GRMEATQISHTLHAPQPMIDAMLNQLEIMGKAVRIPEEPD.......... 54
15 -10.200IDP00779 gene: sirR; iron-dependent repressor SACOL0691 [Staphylococcus aureus subsp. aureus COL]  ali follow..  21  1.................................................................................................................................................................................................................................................MLTEEKEDYLKAILTNNGDKNFVTNKILSQFLNIKPPSVSEMVGRLEKAGYVETKPDGLTHTLDIIKRHR 78
16 -9.680IDP95129 DNA-binding transcriptional repressor AllR [Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044] YP_002918201 [Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044]  ali follow..  12  2...........................................................................................................................................................................................................................TEVRRRGRPGQQEPSAQKGAQALERGI-----AILQYLEKSGGSSSVSDISLNLDLPLSTTFRLLKVLEGADFVYQDSQLGWWHIGLG.... 84
17 -9.570IDP00113 gene: blaI; PENICILLINASE REPRESSOR NT01SAA0015 [Staphylococcus aureus subsp. aureus N315]  ali follow..  15  7....................................................................................................................................................................................................................................................EISMAEWDVMNIIWDKKSVSANVEIQKYKEVSDKTIRTLITRLYKKEIIKRYKSENIYF........ 68
18 -9.560IDP01622 gene: ytfB; putative cell envelope opacity-associated protein A [Salmonella typhimurium LT2] STM4396 [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]  ali follow..  52.................................................................................................................................................................................ETSDSPVVTREAQLDLQSQSQPPTEAQLQAQLVAPQNDPDQVAPVAPEPIQEGQPEEQNQPQTQPFQQDSGIGQQWRSYRVESGKTL--AQLFRDHGLPPTDVYAMAQVEGAGKPLSNLKNGQMIKIRQNASGV 183
19 -9.550IDP92027 DNA-directed RNA polymerases III, 39 kDa polypeptide, putative [Toxoplasma gondii ME49] TGME49_017580 [Toxoplasma gondii ME49]  ali follow..  11  88...........................................................................................................................................................................................................................................PSNVIGKLKTLDAFDYKVYCAIEQAGTTVWTADLRKSTGLQTHIIQRSVKQLDFLKLIKPVKHVKNRKMYILAHLE 167
20 -9.480IDP00219 probable deoR-family transcriptional regulatory protein YPO1938 [Yersinia pestis CO92]  ali follow..  17  5.......................................................................................................................................................................................................................................................ERHQKILALVAER-GVVSIAELTERLGVSHMTIRRDVQKLEEQGAVLSVSGG............ 55
21 -9.360IDP91880 hypothetical protein lmo0753 [Listeria monocytogenes EGD-e] NP_464280 [Listeria monocytogenes EGD-e]  ali follow..  14  151....................................................................................................................................................................................................................................................SEDSVRAKISNYLFGIQDDETREEIADYLDITRPSLSRELGRMQKENIIR-----EGSSVIILDAII 220
22 -9.220IDP01519 hypothetical protein VC2149 VC2149 [Vibrio cholerae O1 biovar El Tor str. N16961]  ali follow..  12...........................................................................................................................................................................................................................................................YLALLV-ESLERPNVPKLIEKTGWPRRTIQDVIKAMPGIGIELN................ 54
23 -9.090IDP90992 DNA-binding transcriptional regulator IscR [Yersinia pestis KIM 10] y1333 [Yersinia pestis KIM10+]  ali follow..  17  23....................................................................................................................................................................................................................................................RLTSKGRYAVTAMLDQDGPVPLADISERQGISLSYLEQLFSRLRKNGLVASVR-GPGGGYLLGKDAS 93

FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Li W, Godzik A. Discovering new genes with advanced homology detection. Trends Biotechnol. 2002 Aug;20(8):315-6.