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Query: [G] COG3958 Transketolase, C-terminal subunit, from VFDB

Results of FFAS03 search in CSGID
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MIKLAPAGLKDDIEMRKVYAGFIAGQIEAGSPIIALEADLMSSMAMDSVARDYPQHVINCGIMEANVIGTAAGLALTGRKPFVHTFTAFASRRCFDQLFMALDYQRNNVKVIASDAGVTACHNGGTHMSFEDMGIVRGLAHSVVLEVTDAVMFADILRQLMDLDGFYWLRTIRKQARSIYAPGSTFTIGKGNVLREGDDITLIANGIMVAEALEAARQLEQEGVSAAVIDMFTLKPIDRMLVKNYAEKTRRIVTCENHSIHNGLGSAVAEVLVENCPVPMRRVGVKERYGQVGTQDFLQKEYGLTAEAIVEAAKSLLLast
1 -110.000IDP02011 putative transketolase [Salmonella typhimurium LT2] STM2340 [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]  ali follow..  100  1MIKLAPAGLKDDIEMRKVYAGFIAGQIEAGSPIIALEADLMSSMAMDSVARDYPQHVINCGIMEANVIGTAAGLALTGRKPFVHTFTAFASRRCFDQLFMALDYQRNNVKVIASDAGVTACHNGGTHMSFEDMGIVRGLAHSVVLEVTDAVMFADILRQLMDLDGFYWLRTIRKQARSIYAPGSTFTIGKGNVLREGDDITLIANGIMVAEALEAARQLEQEGVSAAVIDMFTLKPIDRMLVKNYAEKTRRIVTCENHSIHNGLGSAVAEVLVENCPVPMRRVGVKERYGQVGTQDFLQKEYGLTAEAIVEAAKSLL 317
2 -102.000IDP90935 C-terminal region of transketolase [Yersinia pestis CO92] YPO3313 [Yersinia pestis CO92]  ali follow..  26  1........MSNAEHLASVMVEQFIKAVDNGVDLVPVVADSTSTAKIGPFITRFPDRVVNVGIAEQAMVGMAVGLSMGGKIAVTCNAAPFLISRANEQLKIDVCYNNSNVKLFGLNSGASYGPLASTHHCIDDIAILRGFGNIEIYAPADPQECRQIIDYALAHQGPVYIRLDGKALPPLHDEHYRFAPGQIDVLQEGRDIALVAMGSTVHEAVSAAAILADNNISAAVVNVSSIRPCDTQQLFAILQQSQRVITIEEHNINGGVGSLVAEVLAEAGGTPLVRLGIPDGYAIAADRAEMRAYHGFDAAGIVARALRFC 311
3 -84.200IDP02217 gene: dxs; 1-deoxy-D-xylulose-5-phosphate synthase [Francisella tularensis subsp. tularensis SCHU S4] FTT1018c [Francisella tularensis subsp. tularensis SCHU S4]  ali follow..  21  304..GENITTKISKPTYSNIFGDWICQKAAKDKRLVGITPAMKEGSDLIRFSQLYPHRYFDVAIAEQHAVTFAGGLACQGLKPVVAIYSTFL-QRAYDQVIHDIALQNLDVLYAVDRAGL-VGADGATHDGSFDLAFMRCIPNHVIMTPSDENEAYHMLEFGYEYNGPAMVRYPRGAGIGAITGSLDLELGKAKIVKQGSKIAILNFGTLLPLAKQLAE-----KYHATVIDMRFVKPLDEIMLDKVSQTHEIILTLEENCIAGGAGSAVNEYFVAKDKIIVRNFGLQDKFLNHGTKDLLLAQSKLCVENISQELDKLI 615
4 -84.200IDP90880 gene: dxs; 1-deoxy-D-xylulose-5-phosphate synthase [Yersinia pestis CO92] YPO3177 [Yersinia pestis CO92]  ali follow..  27  311....LPKSQSSLPTYSKIFGEWLCETAAKDSKLMAVTPAMREGSGMVRFSREYPQQYFDVAIAEQHAVTFAAGLAIGGYKPVVAIYSTFLQ-RAYDQLIHDVAIQNLPVLFAIDRGGL-VGADGQTHQGAFDLSFMRCIPNMVIMAPSDENECRQMLYTGYHHNGPAAVRYPRGNGTSALEPLEMLPIGKGVLRREGEKIAILCFGTLLAQAQLAAE-----NLNATLVDMRFVKPLDEELVLEMAAKHQVLVTVEENAIMGGAGSGVNELLMAKRWVPVLNIGLPDLFVPQGEQDEMRSELGLDAAGIQRQIEAWL 618
5 -83.500IDP00089 gene: dxs; 1-deoxyxylulose-5-phosphate synthase; flavoprotein NT01ST0526 [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]  ali follow..  27  311....LPKSSGGLPGYSKIFGDWLCETAAKDSKLMAITPAMREGSGMVEFSRKFPDRYFDVAIAEQHAVTFAAGLAIGGYKPVVAIYSTFL-QRAYDQVIHDVAIQKLPVMFAIDRAGI-VGADGQTHQGAFDLSYLRCIPDMVIMTPSDENECRQMLFTGYHYDGPTAVRYPRGNAQGVLTPLEKLPIGKGLVKRHGEKLAILNFGTLMPEAAKVAE-----ALNATLVDMRFVKPLDDTLILEMAAQHDALVTLEENAIMGGAGSGVNEVLMAHRPVPVLNIGLPDFFIPQGTQEEARAELGLDAAGIEAKIKAWL 619
6 -60.900IDP90564 gene: tkt; transketolase [Campylobacter jejuni subsp. jejuni NCTC 11168] Cj1645 [Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819]  ali follow..  17  328..IAYPDFKGKDLATRDSNGEILNVLAKNLEGFLGGSADLGPSTELHSMGDFVEGKNIHFGIREHAMAAINNAFARYGFLPFSATFFIFSE-YLKPAARIA-ALMKIKHFFIFTHDSIGVGEDGPTHQPIEQLSTFRAMPNFLTFRPADGVENVKAWQIALNADIPSAFVLSRQKLKALNEPVFGDVKNGAYLLKESKKFTLLASGSEVWLCLESANELEKQGFACNVVSMPCFELFEKQDKAYQERLLGEVIGVEAAHSNELYKFCHK------------VYGI-ESFGESGKDKDVFERFGFSVSKLVNFILS.. 631
7 -57.000IDP02743 gene: bfmbAb; 3-methyl-2-oxobutanoate dehydrogenase, beta subunit [Bacillus anthracis str. `Ames Ancestor`] GBAA4383 [Bacillus anthracis str. `Ames Ancestor`]  ali follow..  19  2..........AVMSYIDAITLAMREEMERDEKVFVLGEDVGKKGGVGLYDQFGEDRALDTPLAESAIAGVAIGAAMYGMRPIAEMQFADFIMPAVNQIVSEAAKIRYRSN-ITVRAPFGGGVHGALYHSQSVEAMFANQPGLKIVIPSTPYDAKGLLKAAIRDEDPVLFRAYRLIKGEVPEDDYVLPIGKADVKREGDDITVITYGLCVHFALQAAEKLAQDGISAHILDLRTVYPLDKEAIIEAASKTGKVLLVTEDNKEGSIMSEVAAIIAENCDAPIARLAGPDVPAMPYAPT-MEKFFMVNPDKVEKAMRELA 325
8 -56.300IDP02703 gene: tkt-1; transketolase [Bacillus anthracis str. `Ames Ancestor`] GBAA3432 [Bacillus anthracis str. `Ames Ancestor`]  ali follow..  22  353..DILSFDSEKTISTRVASGEAINHYVKSIPSIFGGSADLSHSTMTDIKVESYAGRNIYFGVREHAMGAAANGLALHGVKPFVSTFFVFND-YLRPSIRLA-ALQKLPVTYVFTHDSIAVGEDGPTHEPIEHLAALRAIPGLTVIRPSDANETASAWAYALQTEGPVVLVLSRQNLPVFHETKANIENLSKTQTNENPDVILIATGSEVSLAASAKAKLEEDNVSVRIVAMPSWELFDRQSK-EYKESVLPSSVTKRVSLEMGVSLGWERYVGQEG----NILSI-ETFGASGTGAEVMNLFGFTTENVVQITKNVL 672
9 -53.500IDP02454 gene: tkt-2; transketolase [Bacillus anthracis str. `Ames Ancestor`] GBAA3744 [Bacillus anthracis str. `Ames Ancestor`]  ali follow..  20  345..NLPTYELGSKAATRNSSGAVINAIAESVPSFFGGSADLAGSNKTDFTRDDYSGKNIWYGVREFAMGAAMNGIALHGLKTYGGTFFVFSD-YLRPAIRLA-ALMQLPVTYVFTHDSIAVGEDGPTHEPIEQLAALRAMPNVSVIRPADGNESVAAWRLALETNKPTALVLTRQDLPTLEGAKDDTYEKVAASKKETADVILLATGSEVSLAVEAQKALAVDGVDASVVSMPSMDRFEAQTA-EYKESVLPKAVTKRFAIEMGATFGWHRYVGLEG----DVLGI-DTFGASAPGEKIMEEYGFTVENVVRKVKEML 666
10 -53.400IDP00790 gene: pdhB; pyruvate dehydrogenase complex E1 component, beta subunit SACOL1103 [Staphylococcus aureus subsp. aureus COL]  ali follow..  21  2..........AQMTMVQAINDALKTELKNDQDVLIFGEDVGVNGGVFRVTEGLEDRVFDTPLAESGIGGLAMGLAVEGFRPVMEVQFLGFVFEVFDAIAGQIARTRFRSG-VTIRGPFGGGVHTPELHADNLEGILAQSPGLKVVIPSGPYDAKGLLISSIRSNDPVVYKLYRSFREEVPEEEYTIDIGKANVKKEGNDISIITYGAMVQESMKAAEELEKDGYSVEVIDLRTVQPIDVDTIVASVEKTGRAVVVQEAQRQAGVGAAVVAELSERAEAPIGRVAAADTIYPFTQ---AENVWLPNKNDIIEKAKETL 323
11 -53.300IDP02310 gene: tktA; transketolase [Francisella tularensis subsp. tularensis SCHU S4] FTT1369c [Francisella tularensis subsp. tularensis SCHU S4]  ali follow..  15  343DYIASQLSNPVKVATRKASQMVLEVLCKNMPEMFGGSADLTGSNNTNWSNTQEGANYLSYGVREFGMAAIMNGLSLYGIKPYGGTFLVFSD-YSRNAIRMS-ALMKQPVVHVMSHDSIGLGEDGPTHQPIEHVPSLRLIPNLSVWRPADTIETMIAWKEAVKSDTPSVMVLTRQNLMPVVQTQHQVA-GYLVKDNPDAKLTIVATGSEVELAVKVANEFEKKGIKLNVASIPCVEVFATQYKKTVIKDDIPAVFVEMAQPD-MWYKYMPK-------AGGEVKGI-YSFGESAPAEDLFKRFGFTVENISNIVAKYV 663
12 -51.100IDP02496 gene: pdhB; pyruvate dehydrogenase complex E1 component, beta subunit [Bacillus anthracis str. `Ames Ancestor`] GBAA4183 [Bacillus anthracis str. `Ames Ancestor`]  ali follow..  19  2..........AQMTMIQAITDALRVEMKNDPNVLVFGEDVGVNGGVFRATEGLEDRVMDTPLAESGIGGLAVGLALEGFRPVPEIQFFGFVYEVMDSISGQLARMRYRSG-VTVRSPFGGGVHTPELHADSLEGLVAQQPGLKVVIPSTPYDAKGLLISAIRDNDPVIYKLYRSFRQDVPEGEYTIDLGKADIKREGTDVSVIAYGAMVHAALKAAEELEKEGISLEVVDLRTVQPLDIETIIASVEKTGRVVVVQEAQKQAGIAANVVAEINDRAEAPVVRVAAADTVFPFSQ---AESVWLPNHKDIVEAVNKVM 323
13 -50.200IDP00613 gene: tkt; transketolase SACOL1377 [Staphylococcus aureus subsp. aureus COL]  ali follow..  19  343..ELPRFELGHNGASRADSGTVIQAISKTVPSFFGGSADLAGSNKSDYSSETPEGKNVWFGVREFAMGAAVNGMAAHGLHPYGATFFVFSD-YLKPALRLS-SIMGLNATFIFTHDSIAVGEDGPTHEPIEQLAGLRAIPNMNVIRPADGNETRVAWEVALSESTPTSLVLTRQNLPVLDVPEEGVRKGAYTVYGETPEFLLLASGSEVSLAVEAAKDLEKQGKSVRVVSMPNWNAFEQQSEE-IPSSVTKRVAIEMASPLG---------WHKYVGTAGKVIAI-DGFGASAPGDLVVEKYGFTKENILNQVMSL. 662
14 -49.800IDP02425 gene: acoB; TPP-dependent acetoin dehydrogenase E1 beta-subunit [Bacillus anthracis str. `Ames Ancestor`] GBAA2775 [Bacillus anthracis str. `Ames Ancestor`]  ali follow..  19  1........MTRTVSMSTAINEAMKISMRRDENVILIGEDVAGGAQVDHLQDD-RNRILDTPISEAGYMGAAMAAAATGLRPIAELMFNDFIGSCLDQVLNQGAKFRYMFG-VTVRTMHGAGFSAAAQHSQSLYALFTSIPGIKVVVPSTPYDAKGLLLAAIEDDDPVIFFEDKNMKGEVPEGYYTIPLGKADIKREGSDVTIVAIGKQVHTALAAAEQLAKKGLEVEVIDPRSLSPLDEDTILSSVEKTNRLIVIDEANPRCSIATDIAAIVADRGDAPIKRITAPHTPVPFSPP--LEKLYLPTPEKVIETVSEMI 336
15 -45.600IDP02700 gene: aceE; pyruvate dehydrogenase subunit E1 [Yersinia pestis CO92] YPO3419 [Yersinia pestis CO92]  ali follow..  15  488.......EQNKEISTTIAFVRALNVMLKNKSRIVPIIADEARTFGMEGLKEDEKGQILQEGINELGAASSWLAAATSYMIPFYIYYSMFGFQRIGDLCWAAGDQQARGFLIGGTSGRTTLNGEGLQHEDGHSHIQSLTIPNCISYDPAYAYEVAVIMHDGLERQENVYYYLTTLNENYHMPAMPQ---GIYKLEGSKGKVQLMSSGAILRHVREAAQILAKDGVGSDVYSVTSFTELARDGQDCERWNMHPTETPRVPYVAQVMNDAPAVASTDYMKLEFRVLGT-DGFGRSDSRENLRHHFEVDSSYVVVAALGEL 857
16 -14.400IDP90568 gene: oorA; 2-oxoglutarate-acceptor oxidoreductase subunit OorA [Campylobacter jejuni subsp. jejuni NCTC 11168] Cj0536 [Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819]  ali follow..  13  9...............NVLIAKAAIDCGCKFFGGYPITPSSEIAHELSHMLPANDGTFIQM--DEISGISVAIGAAMSGVKSMTASSGPGISLKA-EQIGLAFIAEIPLVIVNVMRGGPSTGLPTRVAQG--DLFQAKAPTHSIAIAPASLEETIRAFNLAEKYMTPVFLLMDETEDGVIVKKNMERLIGKIKNNQDDAEFLIIAYGSVSRSAKEAIQRLREQGIKVGLFRPITLYPVAEKKIAEVVSKFKKVMVSELN--MGQYLEEIERVTSRRDFISLHRAN--------GRP--------ITPSEIIAKVKENI 374
17 -12.700IDP06147 gene: oorA; 2-oxoglutarate-acceptor oxidoreductase subunit OorA [Helicobacter pylori J99] NP_223255 [Helicobacter pylori J99]  ali follow..  14  9...............NELVAKAAIEVGCRFFGGYPITPSSDIMHAMSVALPKCGGHFIQM--DEISGISVSLGASMSGTKSMTASSGPGISLKV-EQIGYSFMAEIPLVIADVMRSGPSTGMPTRVAQG--DVNFLRHPIHAVALAPANLEETVRAFNLAEMLMTPVFLLMDETEDAKIGGDLIDRLFHKIESKQEGTEIVIIAYGSVSLAVKEALKDYKESKQKVGFFRPKTLWPSPAKRLKEIGDKYEKILVIELNK--GQYLEEIERVMQRKVHFFGQANGRT-----------------ISPKQIIAKLKEL. 375
18 -10.300IDP90660 pyruvate ferredoxin/flavodoxin oxidoreductase [Campylobacter jejuni subsp. jejuni NCTC 11168] Cj1476c [Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819]  ali follow..  10  11...................NEAAAYAAYAFTEVAGIYPITPSSPMADYTDMWAAAGKKNL--SEAGAAGSVHGSLQAGALTTTYTASQGLLLKI--PNMYKIAGQLLPCVIHVAARSLA-AQALSIFGDHQDIYAARQI-GFAMLCSHSVQETMDLALAAIKGRVPFLFRTSHEIQKVEVMDYAHFDTGREYKPHKEPECVIVAMGSVTQALEEVVDYLNAKGEKVGILKVYLYRPFSLKYFFDVMKSVKKIAVLDRTKEPGSLGEPLYLDVKSAFYGRENAPVIVGGRYGLSSKD-------VDPAQMIAVFENLK 382
FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Li W, Godzik A. cd-hit: a fast program for clustering and comparing large sets of protein or nucleotide sequences. Bioinformatics. 2006 May 26;