current user: public

If you have questions about the server, please let us know.

Query: [R] COG4624 Iron only hydrogenase large subunit, C-terminal domain, from VFDB

Results of FFAS03 search in CSGID
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
    .   10    .   20    .   30    .   40    .   50    .   60    .   70    .   80    .   90    .  100    .  110    .  120    .  130    .  140    .  150    .  160    .  170    .  180    .  190    .  200    .  210    .  220    .  230    .  240    .  250    .  260    .  270    .  280    .  290    .  300    .  310    .  320    .  330    .  340    .  350    .  360    .
# Score Template Links and tools%idFirst MDALIRPPMSFFADLPKDNKKCIKIGSPLALSLSDCLACSGCVSADEAGALSEDLSFVLDLSPQTSFVLSPQSKINIFNLYREDGMEYREFEAVLSSFLRSKFNIHRIVDTSYLRSKIYEETYREYMATNHLIVSACPGVVTYIERTAPYLIGYLSRVKSPQQMAFSLVKGSRTVSVMPCQDKKLENGRDGVKFDFILTTRGFCKALDSLGFRRPARASGKSLCSMEEAETTQWNIGTSSGGYAEFILGKHCVVETREIRNGIKEHLLDDGRTISQITGLENSINYFKSSKTKGPRHKMTEIFLCKNGCIGGPGQERVNDVEMDIREYDRNGREQPRIFYSSPGLEEKRVFREVKAKRVDLRVDWLast
1 -18.500IDP90516 gene: oorD; 2-oxoglutarate-acceptor oxidoreductase subunit OorD [Campylobacter jejuni subsp. jejuni NCTC 11168] Cj0535 [Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819]  ali follow..  15  3MTAPKDTPVWVDEHRCKACNICVSYCPAGVLAMRDCIGCTECEIHCPDFAIMVAKRDEFKFAKLTAEAKDRAVAVK................................................................................................................................................................................................................................................................................................. 95
2 -17.200IDP00452 electron transport complex protein RnfB YPO2245 [Yersinia pestis CO92]  ali follow..  14  111.........FIDEANCIGCTKCIQACPVDAIIGDLCTGCDLCVAPCPTDCIETTTANWKWDLNTIPVKNLPN..................................................................................................................................................................................................................................................................................................... 188
3 -16.100IDP06055 ferredoxin [Helicobacter pylori J99] NP_222983 [Helicobacter pylori J99]  ali follow..  19  4..........LVNDECIACDACREECPSEAIEEDRCTECPRCVSVCPVDAILPDPNNAESKEELKYEILKEQ..................................................................................................................................................................................................................................................................................................... 83
4 -15.100IDP02246 gene: rnfB; Iron-sulfur cluster-binding protein [Francisella tularensis subsp. tularensis SCHU S4] FTT0649c [Francisella tularensis subsp. tularensis SCHU S4]  ali follow..  10  75.......VAKIDESMCIGCEKCLLACPVDAIIEAECTGCELCVEPCPMDCISLVDLAADKQPNNLTNHAYTTQKNHYRDRYEYHKQRVSQTKAKQRDVYKNIATAQEIDKKAYIAASLAKFRNKKKSSPT........................................................................................................................................................................................................................................... 207
5 -15.000IDP02723 gene: nuoI; NADH dehydrogenase subunit I [Francisella tularensis subsp. tularensis SCHU S4] FTT0039 [Francisella tularensis subsp. tularensis SCHU S4]  ali follow..  14  60............EERCIACKLCEVVCPALAITINKCIFCGYCEESCPVDSIVETNILEYHFEERGENIMTKAKLLAIGDKYEA.......................................................................................................................................................................................................................................................................................... 149
6 -14.900IDP01812 ferredoxin [Francisella tularensis subsp. tularensis SCHU S4] FTT1764c [Francisella tularensis subsp. tularensis SCHU S4]  ali follow..  10  4..........VVTESCIKCKDCVEVCPVDCINPDECIDCALCEPECPVNAIKSSDDLSENEENRELAGIWPNIVEK................................................................................................................................................................................................................................................................................................. 85
7 -14.800IDP91439 ferredoxin [Vibrio vulnificus CMCP6] VV1_0471 [Vibrio vulnificus CMCP6]  ali follow..  16  1.......MALLITDKCINCDMCDPECPNGAISMGDCTECKTCQSVCPITKCIITDPNHIETEEQLLE.......................................................................................................................................................................................................................................................................................................... 75
8 -14.800IDP06075 gene: nuoI; NADH dehydrogenase subunit I [Helicobacter pylori J99] NP_223907 [Helicobacter pylori J99]  ali follow..  12  79............SERCIGCGLCEKICTSNCIRIIRCIYCGLCAEVCPELAIVMGNRFENASTQRSQYGSKSEFLTS................................................................................................................................................................................................................................................................................................. 161
9 -13.800IDP04528 gene: napH; quinol dehydrogenase membrane component [Salmonella typhimurium LT2] STM2257_1_289 [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]  ali follow..  11  222...........KREKCNRCMDCFHVCPEAQVTHRDCMTCGRCVDVCSEDVFTITIRNIIRDASR............................................................................................................................................................................................................................................................................................................. 288
10 -12.800IDP00453 putative iron-sulphur protein YPO2969 [Yersinia pestis CO92]  ali follow..  20  135..........ICQNTYIYCDSCADYCEKQALIWELCDGCGECVFRCPARILEMQI...................................................................................................................................................................................................................................................................................................................... 189
11 -11.900IDP01308 iron-sulfur cluster-binding protein VC1516 [Vibrio cholerae O1 biovar El Tor str. N16961]  ali follow..  13  412.......TIECQTSDCTLCMSCVAVCPTRALHLAGCVQCGLCVKACPEQVLSATPQLNWNKAARQGVVTLHQEEPA----------------------KCLRCHKPFAPQSMITMLQTKLRGHSHFATPEALRIAMCED-VDMFEAMAHDPEQQL.................................................................................................................................................................................................................. 551
12 -10.800IDP02592 glycolate oxidase, iron-sulfur subunit, putative [Bacillus anthracis str. `Ames Ancestor`] GBAA1308 [Bacillus anthracis str. `Ames Ancestor`]  ali follow..  23.............LNCMRCGFCLPTCPTYIQSLNVCLGCRACEPVCPSG-----------------VNYGHLLEEARDIINQNKKFSMPVRAVRKVV-FEELFPHQNRMRTLTGLIGFYQRSGLQTITHKTGIMKLFPETLATMDLVLPKVPKMKAMKDRPTFLPAESTKKKQVAFFTGCLMDTMFLETNNATMKLLGHAGEKSGAKELAKRNIKAFEDLNIDYIITNAGGCGAYLVDYDYLLKDDPQWAGRAKQFVSKIKDITAILVELDFH-CHLRNVMRTSSEPRMLLEAIQGATYREM---ADRCCGSAGIYNIVHSELSMEFLDYKMDRVHETDAT........................ 399
13 -10.700IDP01930 gene: narY; nitrate reductase 2 beta subunit [Salmonella typhimurium LT2] STM1578 [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]  ali follow..  169.GQFENTFMMYLPRLCEHCLNCVATCPSGAIDQDKCRGWRLCISGCPYKKIYFNYPRIESGQPTVCSETCVGRIRYLGVLLYDADRIEEAASTEHETDLYERQC--DVFLNPHDPAVIEEALKQGIPQNVIDAAQRSPVYKMAMDW-------KLALPLHPEYRTLPMV--WYVPPLSPIQSYADAGGLP--------HNGNILPAVETLRIPVQYLAN-------------------LSAGDTGPVIRALKRMMAMRHYMRSQTVEGVTDTRAIEEVGLQQVEEMYRYLAIANYEDRFVDAFPERNGC-DGCHGSDTKFNLFNSSRIDAINITEVRDKAEGE...................... 514
14 -10.600IDP93838 nrfc protein [Yersinia enterocolitica subsp. palearctica Y11] YP_006003981 [Yersinia enterocolitica subsp. palearctica Y11]  ali follow..  11  78.GEFPAVKYQFYRHSCQHCDKCVDVCPTGAVNPDLCVGCQYCIAACPYRVRFIHKTNLKQGKQPACVLSCPTKALTFGNLDSPDCELVKLLHQRTVYRAKLHLGTQ................................................................................................................................................................................................................................................................... 208
15 -10.300IDP01082 gene: nrfC; putative formate-dependent nitrite reductase STM4279 [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]  ali follow..  11  78.GTFPDVKYRFFRHSCQHCDHCVDVCPTGAVNPDLCVGCQYCIAACPYRVRFIHKTNLKAGKQPACVESCPTKALTFGNLDDPNSDISRLLRQKTTYRYKLALGTK................................................................................................................................................................................................................................................................... 208
16 -10.300IDP00930 putative hydrogenase protein STM0612 [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]  ali follow..  14  43.DIYPHEERAFYSLACNHCEHCVAACPVEAHNPERCIGCKNCIRNCPYGAPRFNYERLDIGMNPACVNACPVGALSIID.............................................................................................................................................................................................................................................................................................. 144
17 -10.200IDP01006 putative anaerobic dimethylsulfoxide reductase STM2529 [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]  ali follow..  14  68.....NVFAYTLSISCNHCADCTKNCPTTAVDTDKCVGCGYCAWSCPYGAPQLNVDLLAKGEPPVCVATCPLEAIKFGP.............................................................................................................................................................................................................................................................................................. 166
18 -10.200IDP00878 putative anaerobic dimethylsulfoxide reductase subunit B STM4306 [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]  ali follow..  16  56.....DTFTYYLSIACNHCDECVSGCPTGAVDDSVCVGCRYCEMRCPYGAPQFDLDRLENNLRPICVDSCPQRALDFGP.............................................................................................................................................................................................................................................................................................. 154
19 -10.000IDP01518 formate dehydrogenase, iron-sulfur subunit VC1512 [Vibrio cholerae O1 biovar El Tor str. N16961]  ali follow..  47.....EPGENSISVACMHCTDCMAVCPADCHNKDLCIGCGYCLFACPFGAPQFPKQAAFGERGKM------------------------------------TFCAGGPETEPGSEEERRKYGANRIAEKLPMCASLCSTKALL-----------AGDAEKISDIFRQRVVERGAKGAGWTNGED..................................................................................................................................................................................... 194
20 -9.920IDP00983 gene: phsB; thiosulfate reductase electron transport protein STM2064 [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]  ali follow..  12  50.ASNALTHFQFVRVSCQHCENCVSVCPTGAVDKSRCIGCDYCVAACPFHVRYLNPQTLAAGQSPACVSVCPTDALKFGR.............................................................................................................................................................................................................................................................................................. 152
21 -9.370IDP02074 gene: hybA; hydrogenase 2 protein HybA [Salmonella typhimurium LT2] STM3149 [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]  ali follow..  98.KDQEENGYAYIKKQCMHCVDCVSVCPVSAYDKDVCTGCRYCMVACPYNVPKYDYNNPFGALHK----------CELCNQKGVERLDKGGLPGCVEVCPAGAVIFGTREELMAEAKKRLALKPGSEYHYPRQTLKTDDTYLHTVPKYYPHL...................................................................................................................................................................................................................... 250
22 -9.210IDP00961 gene: ttrB; tetrathionate reductase complex subunit B STM1385 [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]  ali follow..  16  96.....EVTNVLLPRLCNHCDNCVPVCPVQAVDNKRCVGCAYCVQACPYDARFINHETQTADKHRLEAGLLPACVESCVGGARIIG........................................................................................................................................................................................................................................................................................ 192
23 -9.180IDP00543 gene: fdoH; formate dehydrogenase-O, iron-sulfur subunit YPO4057 [Yersinia pestis CO92]  ali follow..  11  88.EESGKLEWLIRKDGCMHCADCLKACPSEGFQSEHCIGCGYCIAGCPFDVPRMNVDRVGVGQEPACVKTCPTGAIHFGT.............................................................................................................................................................................................................................................................................................. 190

FFAS is supported by the NIH grant R01-GM087218-01
1 4 6 8 3 2   jobs submitted since Jan 1, 2011
Comments and questions to: webmaster

Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Grynberg M, Erlandsen H, Godzik A. HEPN: a common domain in bacterial drug resistance and human neurodegenerative proteins. Trends Biochem Sci. 2003 May;28(5):224-6. Review.