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Query: [H] COG0007 Uroporphyrinogen-III methylase, from VFDB

Results of FFAS03 search in H.sapiens
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MSKADEAAACVIAKSKVALPVMEPGHVWLVGAGPGDPGLLTLHAVNALQQADVIVYDALVDDSCLSLKNATATLEYAGKRGGKPSPRQRDISLRLVELARQGKKVLRLKGGDPFVFGRGAEEALTLVEYHVPFRIVPGVTAGVGGLAYAGIAATHRDINQAVTFLTGHDATGAMPDGVDWAGIARSSPVIVMYMAMKHIGLIAGRLIEAGRSPDEPVAFVCNASLPDQTVLETTLGRAAIEVEAAGLQPPAIVVVGEVVRLRAGLDWIGAMAGKSLVSDPLGKRTQQGVQSALast
1 -50.900sp|Q9H2P9|DPH5_HUMAN Diphthine synthase OS=Homo sapiens GN=DPH5 PE=1 SV=2  ali follow..  14  2..........................LYLIGLGLGDAKDITVKGLEVVRRCSRVYLEAYTS---VLTVGKEALEEFYGRKLVVADREEVEQEADNILKDADISDVAFLVVGDPFGATTHSDLVLRATKLGIPYRVIHNASIMNAV-GCCGLQLYKFGETVSIVFWTDTWRPESFFDKVKGRKIYEPPRYMSVNQAAQQLLEIVQNQRIRGETEETLCVGLARVGADDQKIAAGTLRQMCT--VDLGEPLHSLIITGGSIHPMEMLSLFS....................... 271
2 -5.650sp|P12956|XRCC6_HUMAN X-ray repair cross-complementing protein 6 OS=Homo sapiens GN=XRCC6 PE=1 SV=2  ali   17....EEEQEENLEASGDYKYSGRDSLIFLVDASKAMFESQSEDELTPFDMSIQCIQS-VYISKIISSDRDLLAVVFYGTEKDKNSVNFKNIYVLQELDNPGAKRILELDQ---FKGQQGQKRFQDMMGHGSDYSLSEVLWVCANLFSDV----QFKMSHKRIMLFTNEDNPHGNDSAKASRARTKAGDLRDTGIFLDLMHLKKPGGFDISLFYRDIISIAEDEDLRVHFEESSKLEDLLRKVRAKETRKRALLKLNKDIVI--------SVGIYNLVQKALKPPPIKLYRET 292
3 -5.380sp|Q8NHU2|CT026_HUMAN Uncharacterized protein C20orf26 OS=Homo sapiens GN=C20orf26 PE=2 SV=3  ali   14  5..............................................VLSTDEIVPYDHLI--------------LCTGQQYQVPCPTEADISQHLTNREVPNSSQRRYTGKVPIVYGNT-TTVETLLNLGVSGSRIHLVSAVADALGAAGVTMYRDAILAQWNDGLHPDPIYSASFTTPTKPFRLQCSMFFSFCEKNVDYETFKALNDACLVYDSRLVI-----------------------TNFHTNDIAIRAAGSLTKFSNRY........................... 237
4 -5.280sp|P24928|RPB1_HUMAN DNA-directed RNA polymerase II subunit RPB1 OS=Homo sapiens GN=POLR2A PE=1 SV=2  ali   21  181......................................................................................................................................AHPGEMVGALAAQSLGEPATQ------MTLNTFH-----------YAGVSAKNVT----LGVPRL----KELINISKKPKTPSLTVERAKDILCRLEHTTLRKVTANTAIYYDPNPQSTVVQEWVNVYYEM........................... 299
5 -5.270sp|Q9UKF6|CPSF3_HUMAN Cleavage and polyadenylation specificity factor subunit 3 OS=Homo sapiens GN=CPSF3 PE=1 SV=1  ali   12  8...........................HVLGAA-----MIEIAGVKLLYTGDF---DRHLMAAEIPNIKPDIESTYGTHIHEKREEREARFCNTVHDIVNRGGRGL-----PVFALGRAQELLLILDEYWQNHPELHDIPIYYASSLAKKCMAVYQTYVNAMQININNPFVFKHISNLKSMDHFDDIGPSVVMAGMMQSGLSRELFESWCTDKRNGVIIAVEGTLAKHTTMSGQKLPLKMSVDYISFSAHT--------DYQQTSEFIRALKPPHVILVHGEQNEMARLKAA 280
6 -5.230sp|Q8WZA9|IRGQ_HUMAN Immunity-related GTPase family Q protein OS=Homo sapiens GN=IRGQ PE=1 SV=1  ali   14  27..........................................RLLPPAQDGFEVLGAAELEAVREAFETGGLEAALSWVRSGLERLGSARLDLAVAGKADVGLVVDMLLGGDPGAAPASVPTAPT-ERPNVVLWTVPLGHTGTATTAAAASHPTHYDA---LILVTPGA----TEKDWAQVQALLLPDAPLVCVRTDGEGEDPECLGEGKMENPKGESLKNAGGGGLENALSKGREKCSAGSQKAGSGEGPGKAGSEGLQQVVGMKKSGGGDSERAAALSPEDETWEVLEEA 277
7 -5.210sp|O60423|AT8B3_HUMAN Probable phospholipid-transporting ATPase IK OS=Homo sapiens GN=ATP8B3 PE=2 SV=4  ali   15  38....................NSTRKRMSVLVRKPEGAICLYTKG------ADTVIFERLHRRGAMEFATEEALAAFAQETLRTLCLAYREVAEDIYEDWQQ-----RHQEASLLLQNRAQALQQLLGATAIEDRLQDGVPETIKCLKKSNIKI----------VLTGDKQETAVNIGFACELLSENMLILEE.................................................................................................... 189
8 -5.150sp|P83859|OX26_HUMAN(removed signalp:1-18) Orexigenic neuropeptide QRFP OS=Homo sapiens GN=QRFP PE=2 SV=1  ali follow..  40  88........................................................................................EKTSGPLGNLAEELNGYSRKKGGFSFRFGR.............................................................................................................................................................................. 117
9 -5.150sp|Q9Y5R4|HEMK1_HUMAN HemK methyltransferase family member 1 OS=Homo sapiens GN=HEMK1 PE=2 SV=1  ali follow..  17  142.....EWVLEEVAQRSHAVGSPGSPLILEVGCGSG---AISLSLLSQLPQSRVIAVD--KREAAISLTHENAQRLRLQDR----WIIHLDMTSERSWTHLPWGPMDLIVSNPPYV---FHQDMEQLAPEIRSYEDPAALDGG-------GMDIITHILALAPRLL-------------------KDSGSIFLEVDPRHPELVSSWLQSRPDLYLNLVAVRR....................................................................... 322
10 -5.130sp|P42898|MTHR_HUMAN Methylenetetrahydrofolate reductase OS=Homo sapiens GN=MTHFR PE=1 SV=3  ali   2.....................................NIMALRGDPIGDQWEEEEGGFNYAVDLVKHIRSFGDYFDICVAGYPKGHPEAGSFEADLKHLKE-----KVSAGADFIITQ--RFVKACTDMGITCPIVPGI-----------FPIQGYHSLRQLVKLSKLEVPQEIKDVIE----IKDNDAAIRNYGIELAVSLCQELLASGREMATTEVLKRLGMWTEDPRRPLPWALSAHPKRREEDVRPIFWASRPKSYIYRTQEWDEFPNGR.................. 238

FFAS is supported by the NIH grant R01-GM087218-01
1 4 6 6 2 8   jobs submitted since Jan 1, 2011
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Plewczynski D, Tkacz A, Godzik A., Rychlewski L. A support vector machine approach to the identification of phosphorylation sites. Cell Mol Biol Lett. 2005;10(1):73-89.