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Query: [L] COG0389 Nucleotidyltransferase/DNA polymerase involved in DNA repair, from VFDB

Results of FFAS03 search in H.sapiens
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MRKIIHVDMDCFFAAVEMRDNPALRDIPIAIGGSRERRGVISTANYPARKFGVRSAMPTGMALKLCPHLTLLPGRFDAYKEASNHIREIFSRYTSRIEPLSLDEAYLDVTDSVHCHGSATLIAQEIRQTIFNELQLTASAGVAPVKFLAKIASDMNKPNGQFVITPAEVPAFLQTLPLAKIPGVGKVSAAKLEAMGLRTCGDVQKCDLVMLLKRFGKFGRILWERSQGIDERDVNSERLRKSVGVERTMAEDIHHWSECEAIIERLYPELERRLAKVKPDLLIARQGVKLKFDDFQQTTQEHVWPRLNKADLIATARKTWDERRGGRGVRLVGLHVTLLDPQMERQLVLGLLast
1 -100.000sp|Q9UBZ9|REV1_HUMAN DNA repair protein REV1 OS=Homo sapiens GN=REV1 PE=1 SV=1  ali   32  4.RAPLRPGANPQL-EWQYYQNKILKGKAADIPDSSLSRAEIASCSYEARQLGIKNGMFFGHAKQLCPNLQAVPYDFHAYKEVAQTLYETLASYTHNIEAVSCDEALVDITEIAETKLTPDEFANAVRMEIKDQTKCAASVGIGSNILLARMATRKAKPDGQYHLKPEEVDDFIRGQLVTNLPGVGHSMESKLASLGIKTCGDLQYMTMAKLQKEFGKTGQMLYRFCRGLDDRPVRTEKERKSVSAEINYGIRFTQPKEAEAFLLSLSEEIQRRLEATG......................................................................... 297
2 -91.600sp|Q9UNA4|POLI_HUMAN DNA polymerase iota OS=Homo sapiens GN=POLI PE=1 SV=1  ali   34  28.RVIVHVDLDCFYAQVEMISNPELKDKPLGVQQ----KYLVVTCNYEARKLGVKKLMNVRDAKEKCPQLVLVNGDLTRYREMSYKVTELLEEFSPVVERLGFDENFVDLTELHIRLLVGSQIAAEMREAMYNQLGLTGCAGVASNKLLAKLVSGVFKPNQQTVLLPESCQHLIHSNHIKEIPGIGYKTAKCLEALGINSVRDLQTFSPKILEKELGSVAQRIQKLSFGEDNSPVILSGPPQ.............................................................................................................. 300
3 -81.600sp|Q9Y253|POLH_HUMAN DNA polymerase eta OS=Homo sapiens GN=POLH PE=1 SV=1  ali   38  7.RVVALVDMDCFFVQVEQRQNPHLRNKPCAVVQKSWKGGGIIAVSYEARAFGVTRSMWADDAKKLCPDLLLAQANLTKYREASVEVMEIMSRFAV-IERASIDEAYVDLTSAVQQLTVGAVIVEEMRAAIERETGFQCSAGISHNKVLAKLACGLNKPNRQTLVSHGSVPQLFSQMPIRKIRSLGKLGASVIEILGIEYMGELTQFTESQLQSHFGKNGSWLY................................................................................................................................ 299
4 -76.200sp|Q9UBT6|POLK_HUMAN DNA polymerase kappa OS=Homo sapiens GN=POLK PE=1 SV=1  ali   24  14.LIIVPPNFDKYRAVSKEVKEILADYDPNFMAMSLDEAYLNITWPEDKRRYFIKMGSSVENDNPGKEVNKLSEHERSISPLLFEESPSDVQPPGDPFQVNFEEQNNPQILQNSVVFGSAQEVVKEIRFRIEQKTTLTASAGIAPNTMLAKVCSDKNKPNGQYQILPQAVMDFIKDLPIRKVSGIGKVTEKMLKALGIITCTELYQQRALLSLLFSETSWHYFLHISLGLGSTHLTRDGERKSMSVERTFS-EINKAEEQYSLCQELCSELAQDLQKER......................................................................... 300
5 -75.000sp|Q9UBT6|POLK_HUMAN DNA polymerase kappa OS=Homo sapiens GN=POLK PE=1 SV=1  ali   32  101.NTIVHIDMDAFYAAVEMRDNPELKDKPIAVGS----MSMLSTSNYHARRFGVRAAMPGFIAKRLCPQLIIVPPNFDKYRAVSKEVKEILADYDPNFMAMSLDEAYLNITKHLEERQ----NWPEDKRRYFIKMGSSVE-NDNPGKEVNKLSEHERSISPLLFEEPSDVQPPGDPFQVNFEEQNNPQILQNSVVFGTSAQEVVKEI................................................................................................................................................. 297
6 -67.500sp|Q9UNA4|POLI_HUMAN DNA polymerase iota OS=Homo sapiens GN=POLI PE=1 SV=1  ali   23  1.........................................................................................VTVSGHVYNNQSIN--LLDVLHIRLLVGS--QIAAEMREAMYNQLGLTGCAGVASNKLLAKLVSGVFKPNQQTVLLPESCQHLIHSLHIKEIPGIGYKTAKCLEALGINSVRDLQTFSPKILEKELGSVAQRIQKLSFGEDNSPVILSGPPQSFSEEDSFKKCSSE-VEAKNKIEELLASLLNRVC--QDGRKPHTVRLIIRRYSSEKHYGRES-NYDVMTPMVDILMKLFRNMVNVKHLTLLSVCFCNLKALNTAKKGL.. 273
7 -66.200sp|Q9Y253|POLH_HUMAN DNA polymerase eta OS=Homo sapiens GN=POLH PE=1 SV=1  ali   22  3......................................................................................GPTTAEETVQKEGMRLDSLQIDNLTPDLQLTVGAVIVEEMRAAIERETGFQCSAGISHNKVLAKLACGLNKPNRQTLVSHGSVPQLFSQMPIRKIRSLGGKLASVIEILGIEYMGELTQFTESQLQSHFGKNGSWLYAMCRGIEHDPVKPRQLPKTIGCSKNFPTALATREQVQWWLLQLAQELEERLTKNDNDRVATQLVVSIRVQGDKRLSRCCALTRYDAHKMSHDAFTVIKNCNTSPPLTMLFLCATKFSASAPSS..... 286
8 -64.400sp|Q9UBT6|POLK_HUMAN DNA polymerase kappa OS=Homo sapiens GN=POLK PE=1 SV=1  ali   29  1.................................................................................................................................IEQKTTLTASAGIAPNTMLAKVCSDKNKPNGQYQILPQAVMDFIKDLPIRKVSGIGKVTEKMLKALGIITCTELYQQRALLSLLFSETSWHYFLHISLGLGSTHLTRDGERKSMSVERTF-SEINKAEEQYSLCQELCSELAQDLQ--KERLKGRTVTIKLKNVNFEVKTRASTVVVSTAEEIFAIAKELLKTEIDALRLRLMGVRISSFPNEEDQQRSI.. 229
9 -61.600sp|Q9UBZ9|REV1_HUMAN DNA repair protein REV1 OS=Homo sapiens GN=REV1 PE=1 SV=1  ali   28  1....................................................................................................................................QTKCAASVGIGSNILLARMATRKAKPDGQYHLKPEEVDDFIRGQLVTNLPGVGHSMESKLASLGIKTCGDLQYMTMAKLQKEFGKTGQMLYRFCRGLDDRPVRTEKERKSVSAEINYGIRFTQPKEAEAFLLSLSEEIQRRLE--ATGMKGKRLTLKIMHGICDNIARTVTLATDNAKIIGKAMLNMFHTMKNISDMRGVGIHVNQLVPTNLNPSTC.. 234
10 -53.800sp|Q9UBZ9|REV1_HUMAN DNA repair protein REV1 OS=Homo sapiens GN=REV1 PE=1 SV=1  ali   37  117.SCIMHVDMDCFFVSVGIRNRPDLKGKPVAVTSNRLSRAEIASCSYEARQLGIKNGMFFGHAKQLCPNLQAVPYDFHAYKEVAQTLYETLASYTHNIEAVSCDEALVDITEIAETKLTPDEFANAVRMEIKD........................................................................................................................................................................................................................... 300
11 -23.300sp|Q9Y253|POLH_HUMAN DNA polymerase eta OS=Homo sapiens GN=POLH PE=1 SV=1  ali   15  1................................................................................................................................................................................................................................MCRGIEHDPVKPRQLPKTIGCSKNFPTALATREQVQWWLLQLAQELEERLTKDRNDRVATQLVVSIRVQG-SSLRRCCALTRYDAHKMSHDAFTVIKNCNTSGPLTMLFLCATKFSASAPSS..... 136
12 -20.300sp|Q9UBZ9|REV1_HUMAN DNA repair protein REV1 OS=Homo sapiens GN=REV1 PE=1 SV=1  ali   47  267.SCIMHVDMDCFFVSVGIRNRPDLKGKPVAVTSNR............................................................................................................................................................................................................................................................................................................................ 300
13 -17.700sp|Q9UBT6|POLK_HUMAN DNA polymerase kappa OS=Homo sapiens GN=POLK PE=1 SV=1  ali   13  1........................................................................................................................................................................................................................................................................................LKGRTVTIKLKNVNFEVKTRASTVSVSTAEEIFAIAKELLKTEIDADFPHPLRLRLMGVRISSFPN..... 68
14 -13.300sp|Q9UNA4|POLI_HUMAN DNA polymerase iota OS=Homo sapiens GN=POLI PE=1 SV=1  ali   12  1.................................................................................................................................................................................................................................................SFSEEDSFKK-CSSEVEAKNKIEELLASLLNRVC--QDGRKPHTVRLIIRRYSYGRESRQCPIPYDVMTPMVDILMKLFRNMVNVKHLTLLSVCFCNLKALNTAKKGL.. 123

FFAS is supported by the NIH grant R01-GM087218-01
1 4 6 6 1 8   jobs submitted since Jan 1, 2011
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Plewczynski D, Tkacz A, Godzik A., Rychlewski L. A support vector machine approach to the identification of phosphorylation sites. Cell Mol Biol Lett. 2005;10(1):73-89.