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Query: [K] COG2378 Predicted transcriptional regulator, from VFDB

Results of FFAS03 search in H.sapiens
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MPTDNVVSVVSPYHMEMYNMRKASRLFEIIQILRLARRPVTAQTIADMLEVTARSVYRDIAALQTMRVPIEGERGVGYILRPGFNLPPLMFSIEETEAIVLALAMVDRSGDAELRQAAKKVSDKIAASLPEPLSKTLSANALHAWGSIAPAPAGIDLATVRRAVRDEERLDLCYSDESGVETQRRIRPIAVIYYSETVNIVAWCELRHAIRNFRSDRVLDCAATGSFFKMEGEKLRRLWMSGWQSGQPGGELGRPISGVTLPLast
1 -8.840sp|Q9H171|ZBP1_HUMAN Z-DNA-binding protein 1 OS=Homo sapiens GN=ZBP1 PE=1 SV=2  ali follow..  10  1.........MAQAPADPGREGHLEQ--RILQVLTEAGSPVKLAQLVKECQAPKRELNQVLYRMKKELK-VSLTSPATWCLGGTDPEGEGPAELALSSPAERPQQHAATIPETPGPQFSQQREEDIYRFLKDNGPQRALVIAQAL-----GMRTAKDVNRDLYRMKSRHLLDMD--------------------QSKAWTIYR............................................................ 166
2 -8.180sp|P55265|DSRAD_HUMAN Double-stranded RNA-specific adenosine deaminase OS=Homo sapiens GN=ADAR PE=1 SV=4  ali   18  119.PQRGVDCLSSHFQELSIYQDQEQRILKFLEELGEGK-ATTAHDLSGKLGTPKKEINRVLYSLAKKG-----------KLQKEAGTPPLWKIAVSTQA.................................................................................................................................................................... 203
3 -7.520sp|Q12789|TF3C1_HUMAN General transcription factor 3C polypeptide 1 OS=Homo sapiens GN=GTF3C1 PE=1 SV=4  ali   13  161..................TYRLLKRRNLIIEAVTNLRLIESLFTIQKMIKCCKKSIVRLVRNLSEEGYRTTVIQDGIKKKVDLVVHPSMDQNDPLVRSAIEQVR.............................................................................................................................................................. 261
4 -7.250sp|Q13401|PM2L3_HUMAN Postmeiotic segregation increased 2-like protein 3 OS=Homo sapiens GN=PMS2L3 PE=2 SV=2  ali follow..  18  1................................MNTLQGPVSFKDVARQLDPDEKIAYGDVSHLVSVGYDY................................................................................................................................................................................................ 51
5 -7.250sp|P51814|ZNF41_HUMAN Zinc finger protein 41 OS=Homo sapiens GN=ZNF41 PE=1 SV=2  ali   11  30TPEARIHSVKRYPDLSPGPKGRSSADHAALNSIVSLQASVSFEDVTQHLDPAQRRLYWDVSHLLSVGYQI-PKSEAAFKLEQG---GPWMLEGEAPHQSCSGEAIGKMQQQGIPGGIFFHCERFDQPIGEDSLCSILEELWQDNDQLEQRQENQNNLLSHVKVLIKERGYEHKNIEKIIHVTTKLVPSIKRLHNCDT-ILKHTLNSHNHNRNSATKNLGKIFGNGNNFPHSPSSTKNENAKTGANSCEHDHYEKHLSHKQAP 300
6 -7.220sp|Q12789|TF3C1_HUMAN General transcription factor 3C polypeptide 1 OS=Homo sapiens GN=GTF3C1 PE=1 SV=4  ali   13  3..........SGQDKPHETYRLLKRRNLIIEAVTNLRLIESLFTIQKMIKCCKKSIVRLVRNLSEEGYRTTVIQDGIKKKVDLVVHPSMDQNDPLVRSAIEQVR.............................................................................................................................................................. 111
7 -6.980sp|O00716|E2F3_HUMAN Transcription factor E2F3 OS=Homo sapiens GN=E2F3 PE=1 SV=1  ali follow..  10  170.............PKSPSEKTRYDTSLGLLLLSQSPDGVLDLNKAAEVLKVQKRRIY-DITNVLE-GIHLIKKKSKNNVQWMGCSLSEDGGMLAQCQGLSKEVTELSQE-EKKLDELIQSCTLDLKLLTEDSENQRLAYVTYQDIRKISGLKDQTVI-----VVKAPPETRLEVPDSIESLQASTQGPIEVYL..................................................................... 350
8 -6.970sp|Q14209|E2F2_HUMAN Transcription factor E2F2 OS=Homo sapiens GN=E2F2 PE=1 SV=1  ali follow..  12  121.............PKSPGEKTRYDTSLGLLLLSESEDGVLDLNWAAEVLDVQKRRIY-DITNVLE-GIQLIRKKAKNNIQWVGRGMFEDPTRPGKQQQLGQELKELMNT-EQALDQLIQSCSLSFKHLTEDKANKRLAYVTYQDIRAVGNFKEQTVITRLEVPDRTEDNLQIYLKSTQG--------PIEVYL..................................................................... 302
9 -6.860sp|P78347|GTF2I_HUMAN General transcription factor II-I OS=Homo sapiens GN=GTF2I PE=1 SV=2  ali   12  1............................................LKQAVKVPFALFESFPEDFYVEGLP-------GVPFRR-----PSTFGIPRLEKILRNKAKIKINSSPNVNTTASGVEDLNIIQVTIPDDDNERLSKVEKARQLREQVNDLFSRKFGEAIGMGFPVKVPYRKITINPGCVVVDPPGVSFKAPSYLMRRILDSAEFIK-FTVIR............................................. 192
10 -6.810sp|Q96HY6|DDRGK_HUMAN(removed signalp:1-28) DDRGK domain-containing protein 1 OS=Homo sapiens GN=DDRGK1 PE=1 SV=2  ali follow..  15  165...KEAFVVEEEGVGETMTEEQSQSFLTEFINYIKQSKVVLLEDLASQVGLRTQDTINRIQDLLAEGT-VIDDRG-------------IYITPEELAAVANFIRQRGRVSIAELAQASNSLIA........................................................................................................................................... 275
FFAS is supported by the NIH grant R01-GM087218-01
1 4 6 8 3 2   jobs submitted since Jan 1, 2011
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Grynberg M, Erlandsen H, Godzik A. HEPN: a common domain in bacterial drug resistance and human neurodegenerative proteins. Trends Biochem Sci. 2003 May;28(5):224-6. Review.