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Query: [S] COG3111 Uncharacterized conserved protein, from VFDB

Results of FFAS03 search in H.sapiens
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
    .   10    .   20    .   30    .   40    .   50    .   60    .   70    .   80    .   90    .  100    .  110    .  120    .  130
# Score Template Links and tools%idFirst MKKFAAVIAVMALCSAPVMAAEQGGFSGPSATQSQAGGFQGPNGSVTTVESAKSLRDDTWVTLRGNIVERISDDLYVFKDASGTINVDIDHKRWNGVTVTPKDTVEIQGEVDKDWNSVEIDVKQIRKVNPLast
1 -20.100sp|Q96E14|RMI2_HUMAN RecQ-mediated genome instability protein 2 OS=Homo sapiens GN=RMI2 PE=1 SV=2  ali follow..  11  2....................AAAADSFSGGPAGVRLPRSPPLKVLAEQLRRDAEGGPGAAVWMQGRVVM-ADRGEARLRDPSGDFSVRGERVPRGRPCLVPGKYVMVMGVVQACSPEPCLQAVKMTDLS. 126
2 -19.100sp|P15927|RFA2_HUMAN Replication protein A 32 kDa subunit OS=Homo sapiens GN=RPA2 PE=1 SV=1  ali follow..  16  21..................TQSPGGFGSPAPSQAEKKSRARAQHIVPCTISQLLSATLVSQVTIVGIIRHAEKAPTYKIDDMTAAPMDDTDDTSSENTVVPPETYVKVAGHLRSFQNKKSLVAFKIMPLE. 150
3 -18.800sp|Q13156|RFA4_HUMAN Replication protein A 30 kDa subunit OS=Homo sapiens GN=RPA4 PE=1 SV=2  ali follow..  12  24.....................QLCERDATPAIKTQRPKVRIQDVVPCNVNQLLSSTVFSQVSIVGVIRGAEKASNYKIDDMTAKPIEFGREKVKQVTPLSVGVYVKVFGILKCPTGTKSLEVLKIHVLE. 149
4 -17.600sp|Q9H668|STN1_HUMAN CST complex subunit STN1 OS=Homo sapiens GN=OBFC1 PE=1 SV=2  ali follow..  14  1..................MQPGSSRCEEETPSLLWGLDPVFLAFAKLYIRDILDMKESKQVDVLGTVIGVRERDAYGVDDSTGVINCKLQETIEQKTKIEIGDTIRVRGSIRTYREEREIHATTYYKVD. 156
5 -15.400sp|Q6PI48|SYDM_HUMAN Aspartyl-tRNA synthetase, mitochondrial OS=Homo sapiens GN=DARS2 PE=1 SV=1  ali   25  53...............................................TCGELRSSHLGQEVTLCGWIQYRRQNTFLVLRDFDGLVQVIIPQDESAACEAPVESVVQVSGTVKMPTGEIEIKVKTAELLNA 151
6 -14.400sp|O14862|AIM2_HUMAN Interferon-inducible protein AIM2 OS=Homo sapiens GN=AIM2 PE=1 SV=1  ali follow..  11  245.........................................KAGETPKINTLQTQPLGTIVNGLFVVQKVTEKKKFDLSDNTGKMEVLGVRN--DTMKCKEGDKVRLT-TLSKNGEKLQLTSSTIKVIKA 339
7 -13.800sp|P14868|SYDC_HUMAN Aspartyl-tRNA synthetase, cytoplasmic OS=Homo sapiens GN=DARS PE=1 SV=2  ali follow..  13  41.........................................PDRVLVRVRDLTIQKADEVVWVRARVSRAKGKQCFLLRQQQFNVQALVAVGDHASKQINKESIVDVEGVVSCTQQDVELHVQKIYVISL 147
8 -13.700sp|P41218|MNDA_HUMAN Myeloid cell nuclear differentiation antigen OS=Homo sapiens GN=MNDA PE=1 SV=1  ali follow..  12  277.........VMEIKEASSVSDFNQNFEVPNRIIEIAN-------KTPKISQLYKQASGTMVYGLFMLQKKSVHKKYEIQDNTGSMDVVGSGK--HNIKCEKGDKLRLF-QLRTVDRKLKLVCSFIKVIKA 396
9 -12.800sp|Q6K0P9|IFIX_HUMAN Pyrin and HIN domain-containing protein 1 OS=Homo sapiens GN=PYHIN1 PE=1 SV=1  ali follow..  10  307.........................................RAKKIPKINILHKQTSGYIVYGLFMLHTKIVNRKYEIQDKTGSMAVVG--GECHNIPCEKGDKLRLFCRLRKRENMSKLMSEMHSFIQ. 397
10 -12.400sp|Q16666|IF16_HUMAN Gamma-interferon-inducible protein 16 OS=Homo sapiens GN=IFI16 PE=1 SV=3  ali   7  147.........................................RAKETLKIDILHKQASGNIVYGVFMLHKKTVNQKYEIQDDRGKMDVVG--GQCHNIPCEEGDKLQLFCRLRKKNQMSKLISEMHSFIQ. 237
11 -12.400sp|Q96AH0|SOSB2_HUMAN SOSS complex subunit B2 OS=Homo sapiens GN=OBFC2A PE=1 SV=1  ali follow..  11  2.......................................NRVNDPLIFIRDIKPGLKN--LNVVFIVLEIGRVTSCKVADKTGSITISVWDE--IGGLIQPGDIIRLTGYASMWKGCLTLYTGRGGELQ. 97
12 -12.300sp|Q96I59|SYNM_HUMAN(removed signalp:1-16) Probable asparaginyl-tRNA synthetase, mitochondrial OS=Homo sapiens GN=NARS2 PE=1 SV=3  ali follow..  17  9...........................................SAKLSVRDALGAQNGERIKIQGWIVRSQKEVLFLVNDGSSLESLQV-DSGLDSRELNFGSSVEVQGQLPSKRQNVELKAEKIKVIGN 104
13 -11.700sp|O43776|SYNC_HUMAN Asparaginyl-tRNA synthetase, cytoplasmic OS=Homo sapiens GN=NARS PE=1 SV=1  ali follow..  11  111...........................................EPKCVKIGALEGYRGQRVKVFGWVHRLRRQGKLVLRDGTGYLQCVLADELCQCVLLSTESSVAVYGMLKQAPGGHELSCDFWELIG. 209
14 -10.900sp|Q9BQ15|SOSB1_HUMAN SOSS complex subunit B1 OS=Homo sapiens GN=OBFC2B PE=1 SV=1  ali follow..  14  2...........................................TTETFVKDIKPGLKN--LNLIFIVLETGRVTTCKVADKTGSINISVWDD--VGNLIQPGDIIRLTGYASVFKGCLTLYTGRGGDLQK 94
15 -10.600sp|P56282|DPOE2_HUMAN(removed signalp:1-25) DNA polymerase epsilon subunit 2 OS=Homo sapiens GN=POLE2 PE=1 SV=2  ali follow..  15  151.......................................................TKIGDAIVLGMITQL-KEGKFFLEDPTGTVQLDLSKAQFHSGLYTEACFVLAEGWFEDQ----VFHVNAF..... 215
16 -10.200sp|Q8N163|K1967_HUMAN Protein KIAA1967 OS=Homo sapiens GN=KIAA1967 PE=1 SV=2  ali   10  10..............NPLPGGRNFSGTASTSLLGPPPGLLTPPVATELSQNARHLQGGEKQRVFTGIVTS--------LHDYFGVVEVFFQLSVVKGRLPQLGEKVLVKA-AYNPGQAVPWNAVKVQTLSN 118
17 -10.100sp|Q16666|IF16_HUMAN Gamma-interferon-inducible protein 16 OS=Homo sapiens GN=IFI16 PE=1 SV=3  ali   9  3...............................................KIDILHKQASGNIV--YGMLHKKTVNQKYEIQDDRGKMDVVGTGQ--HNIPCEEGDKLQLF-RLRKKNQMSKLISEMHSFIQI 88
FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Damiano JS, Stehlik C, Pio F, Godzik A., Reed JC. CLAN, a novel human CED-4-like gene. Genomics. 2001 Jul;75(1-3):77-83.