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Query: [S] COG3592 Uncharacterized conserved protein, from VFDB

Results of FFAS03 search in H.sapiens
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MEEETLLEQGYRKYRGADVDIYFNTNICAHSGNCVKGNAELFNLDRKPWIMPDNVPKEEAKRVIHTCPSGALQYIEKLast
1 -12.000sp|P28331|NDUS1_HUMAN NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial OS=Homo sapiens GN=NDUFS1 PE=1 SV=3  ali   20  1....SRFLEGKRAVEDKNIGVKTIMTRCIQCTRCIRFASEIAGVDDLGTTGRGNDMSELSGNIIDICPVGALT.... 82
2 -10.100sp|O00217|NDUS8_HUMAN(removed signalp:1-19) NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial OS=Homo sapiens GN=NDUFS8 PE=1 SV=1  ali follow..  11  88.......................GEERCIACKLCEAICPQAITIEAEPRADGSRRTTRYDIDCQEACPVDAIVEGPN 151
3 -9.230sp|P28331|NDUS1_HUMAN NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial OS=Homo sapiens GN=NDUFS1 PE=1 SV=3  ali   22  169....................VKTIMTRCIQCTRCIRFASEIAGVDDLGTTGRGNDMSELSGNIIDICPVGALT.... 232
4 -8.820sp|P21912|DHSB_HUMAN(removed signalp:1-15) Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial OS=Homo sapiens GN=SDHB PE=1 SV=3  ali follow..  14  145.KDESQEGKQQYLQSIEEREKLDGLYECILCACCSTSCP-SYWWNGDKYLGPDDFTEERLAKLTRTCPKGL...... 242
5 -8.780sp|Q16134|ETFD_HUMAN Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial OS=Homo sapiens GN=ETFDH PE=1 SV=2  ali   18  117........EFVPVEQGDGFRLQINAQNCVHCKTCDI-----------------------------KDPSQNINWV.. 154
6 -7.510sp|Q12882|DPYD_HUMAN Dihydropyrimidine dehydrogenase [NADP+] OS=Homo sapiens GN=DPYD PE=1 SV=2  ali   10  180....QYLGTFGELSNVEQVVAMIDEEMCINCGKCYMTCNQAIQFDPETHLPTITDTCTGCTLCLSVCPVDCIKMVSR 257
7 -6.920sp|O43396|TXNL1_HUMAN Thioredoxin-like protein 1 OS=Homo sapiens GN=TXNL1 PE=1 SV=3  ali follow..  11  7VGSDPDFQPELSGAGSRLAVVKFTMRGC---GPCLRIAPAFSSMSNK-FLEVDVHQCQGTAATISATPT........ 78
8 -6.820sp|Q99466|NOTC4_HUMAN(removed signalp:1-23) Neurogenic locus notch homolog protein 4 OS=Homo sapiens GN=NOTCH4 PE=1 SV=2  ali   11  1.........TDSLSAGFVVVMGVDLSRCGPASRCPWDPGLLLRF----------AAMAAVGALEPLLPGPLLAVHPH 62
9 -6.310sp|Q6A555|TXND8_HUMAN Thioredoxin domain-containing protein 8 OS=Homo sapiens GN=TXNDC8 PE=1 SV=2  ali follow..  14  5IKDTNEFKTFLTAAGHKLAVVQFSSKRC---GPCKRMFPVFHAMSVK--VDVNNSPELAETCHIKTIPT........ 76
10 -6.100sp|P10599|THIO_HUMAN Thioredoxin OS=Homo sapiens GN=TXN PE=1 SV=3  ali follow..  15  5IESKTAFQEALDAAGDKLVVVDFSATWC---GPCKMIKPFFHSLSEK--VDVDDCQDVASECEVKCMPT........ 76

FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Friedberg I. and Godzik A Connecting the Protein Structure Universe by Using Sparse Recurring Fragments. Structure (Camb.) (2005) Aug;13(8):1213-24