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Query: [R] COG4624 Iron only hydrogenase large subunit, C-terminal domain, from VFDB

Results of FFAS03 search in H.sapiens
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MDALIRPPMSFFADLPKDNKKCIKIGSPLALSLSDCLACSGCVSADEAGALSEDLSFVLDLSPQTSFVLSPQSKINIFNLYREDGMEYREFEAVLSSFLRSKFNIHRIVDTSYLRSKIYEETYREYMATNHLIVSACPGVVTYIERTAPYLIGYLSRVKSPQQMAFSLVKGSRTVSVMPCQDKKLENGRDGVKFDFILTTRGFCKALDSLGFRRPARASGKSLCSMEEAETTQWNIGTSSGGYAEFILGKHCVVETREIRNGIKEHLLDDGRTISQITGLENSINYFKSSKTKGPRHKMTEIFLCKNGCIGGPGQERVNDVEMDIREYDRNGREQPRIFYSSPGLEEKRVFREVKAKRVDLRVDWLast
1 -85.800sp|Q9UHQ1|NARF_HUMAN Nuclear prelamin A recognition factor OS=Homo sapiens GN=NARF PE=1 SV=1  ali follow..  21  2..............KCEHCTRKECSKKTKTIFLSDCLACDSCMTAEEGVQLSQQNACDTSKHKVLVVSVCPQSLPYFAAKFNL----SVTDASRRLCGFLKSLGVHYVFDTTIAADFSILESQKEFVRRLPMLTSACPGWVRYAERVLGRITAHLCTAKSPQQVMGSLVKKIFHVIVAPCYDKKLEALQESLGADCVLTSGEIAQIMEQGDLSVRDAAVDTLFGDL-KEDKVTRHDGASSDGHLAHIFRHAAKELFNEDVEEVTYRALEVVLRFAAAYGFRNIQNMILKLKKGKFPFHFVEVLACAGGCLNGRGQAQTPDGHADKALLRQMEGADIPVRRPESSAHVQELYQEWLEGINSLDIKW 456
2 -84.600sp|Q9H6Q4|NARFL_HUMAN Cytosolic Fe-S cluster assembly factor NARFL OS=Homo sapiens GN=NARFL PE=1 SV=1  ali follow..  24  14LDDFIGP-----SQECIKPVKVEKRAGSGVVSLNDCLACSGCITSAETVLITQQSHAAPSQQRLVVVSVSPQSRASLAARFQL----NPTDTARKLTSFFKKIGVHFVFDTAFSRHFSLLESQREFVRRLPLLASACPGWICYAEKTHSFILPHISTARSPQQVMGSLVKKIYHVTVMPCYDKKLEASRPDFDVDCVLTTGEVFRLLEEEGVSLPDLEPAPLDSLCSGASAEESHRGGGSGGYLEHVFRHAARELFGIHVAEVTYKPLQVLLHFAMAYGFRNIQNLVQRLKRGRCPYHYVEVMACPSGCLNGGGQLQAPDRPSRELQHVERLYGMVRAEAPEDAPGVQELYTHWLQGTDSLGIRW 476
3 -14.900sp|O00217|NDUS8_HUMAN(removed signalp:1-19) NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial OS=Homo sapiens GN=NDUFS8 PE=1 SV=1  ali follow..  16  88...........GEERCIACKLCEAICPAQAITIEKCIYCGFCQEACPVDAIVEGPNFEFSTETHEELLYNKEKLLNNGDKWEA.......................................................................................................................................................................................................................................................................................... 178
4 -14.000sp|Q16134|ETFD_HUMAN Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial OS=Homo sapiens GN=ETFDH PE=1 SV=2  ali   10  90....RDDSIPVNRNLSIYDGPEQRFCPAGVINAQNCVHCKTCDIKDPSQNIN......................................................................................................................................................................................................................................................................................................................... 152
5 -9.860sp|P28331|NDUS1_HUMAN NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial OS=Homo sapiens GN=NDUFS1 PE=1 SV=3  ali   9  12.DKNIGPLVKTIMTRCIQCTRCIRFASEIA-KMFMSELSGNIIDICPVGALTSKPYAFTARP---------------------------ETRKTESIDVMDAVGSNIVVSTRTGEVMRILPRMHEDINE---------EWISDKTRFAYDGLKRQRLTEPMVRNEKGLLTYTSWEDALSRVAGMLQSFQGKDVAAIAGGLVDAEALVALKDL......................................................................................................................................................... 207
6 -9.780sp|Q12882|DPYD_HUMAN Dihydropyrimidine dehydrogenase [NADP+] OS=Homo sapiens GN=DPYD PE=1 SV=2  ali   15  197.........MIDEEMCINCGKCYMTCNDSGYQADTCTGCTLCLSVCP.............................................................................................................................................................................................................................................................................................................................. 247
7 -8.990sp|P21912|DHSB_HUMAN(removed signalp:1-15) Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial OS=Homo sapiens GN=SDHB PE=1 SV=3  ali follow..  8  170..............ECILCACCSTSCPSYWWNGDKCHTIMNCTRTCPKGLNPGKAIAEIKKMMATYKEKKASV.................................................................................................................................................................................................................................................................................................... 265
8 -8.720sp|P52943|CRIP2_HUMAN Cysteine-rich protein 2 OS=Homo sapiens GN=CRIP2 PE=1 SV=1  ali follow..  10  2............ASKCPKCDKTVYFAEKVSSL-KFCLKCERCSKTLTPGGHAEHDGKPFCHKPCYATLFGPK--VNIGGAGSYIYEKPLAEGPQVTGPIEVPAARAEERKASGPPKGPSRASSVTTFTGEPNTCPRCSKKVYFAEKWHRPCL-RCERCGKTLTPGGHAEHDGQPYCHKPCYGILF.................................................................................................................................................................................... 183
9 -8.590sp|Q9H2H0|CXXC4_HUMAN CXXC-type zinc finger protein 4 OS=Homo sapiens GN=CXXC4 PE=2 SV=1  ali follow..  11  136............RKRCGVCVPCKRL--------INCGVCSSCRQICKFRKCEELKKKPGTSLERTPVPSAEAFRWFF................................................................................................................................................................................................................................................................................................ 198
10 -8.390sp|Q04656|ATP7A_HUMAN Copper-transporting ATPase 1 OS=Homo sapiens GN=ATP7A PE=1 SV=3  ali   13  38..........................SKCYIQVTG-MTCASCVANIERNLRREE---------------IYSILVALMAGKAEVRYNPAVIQPPMIAEFIRELGFG--------ATVIENADEGDGVLELVVRGMTCASCVHKIESS-------LTKHRGILYCSVALATNKAHIKYDP-----------------IIGPRDIIHTIESLGFEASLVKKDRSASHLDHKRE...................................................................................................................................... 196
FFAS is supported by the NIH grant R01-GM087218-01
1 4 6 8 2 5   jobs submitted since Jan 1, 2011
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Luz JG, Hassig CA, Pickle C, Godzik A., Meyer BJ, Wilson IA. XOL-1, primary determinant of sexual fate in C. elegans, is a GHMP kinase family member and a structural prototype for a class of developmental regulators. Genes Dev. 2003 Apr 15;17(8):977-90. Epub 2003 Apr 02.